Publication list - Publika - Scientific publications from Oslo University Hospital

Publications by Anette Weyergang

45 publications found

Original articles

Longva AS, Berg K, Weyergang A (2023)
Light-enhanced VEGF₁₂₁/rGel induce immunogenic cell death and increase the antitumor activity of αCTLA4 treatment
Front Immunol, 14, 1278000
DOI 10.3389/fimmu.2023.1278000, PubMed 38173721

Weisheit S, Wegner CS, Ailte I, Radulovic M, Weyergang A, Selbo PK, Brech A (2021)
Inhibiting autophagy increases the efficacy of low-dose photodynamic therapy
Biochem Pharmacol, 194, 114837
DOI 10.1016/j.bcp.2021.114837, PubMed 34780750

Engebraaten O, Yau C, Berg K, Borgen E, Garred Ø, Berstad MEB, Fremstedal ASV, DeMichele A, Veer LV', Esserman L, Weyergang A (2021)
RAB5A expression is a predictive biomarker for trastuzumab emtansine in breast cancer
Nat Commun, 12 (1), 6427
DOI 10.1038/s41467-021-26018-z, PubMed 34741021

Berstad MEB, Cheung LH, Weyergang A (2020)
Production of Recombinant Gelonin Using an Automated Liquid Chromatography System
Toxins (Basel), 12 (8)
DOI 10.3390/toxins12080519, PubMed 32823678

Wong JJW, Berstad MB, Fremstedal ASV, Berg K, Patzke S, Sørensen V, Peng Q, Selbo PK, Weyergang A (2020)
Photochemically-Induced Release of Lysosomal Sequestered Sunitinib: Obstacles for Therapeutic Efficacy
Cancers (Basel), 12 (2)
DOI 10.3390/cancers12020417, PubMed 32053965

Olsen CE, Cheung LH, Weyergang A, Berg K, Vallera DA, Rosenblum MG, Selbo PK (2019)
Design, Characterization, and Evaluation of scFvCD133/rGelonin: A CD133-Targeting Recombinant Immunotoxin for Use in Combination with Photochemical Internalization
J Clin Med, 9 (1)
DOI 10.3390/jcm9010068, PubMed 31888091

Weyergang A, Fremstedal AS, Skarpen E, Peng Q, Mohamedali KA, Eng MS, Cheung LH, Rosenblum MG, Waltenberger J, Berg K (2018)
Light-enhanced VEGF₁₂₁/rGel: A tumor targeted modality with vascular and immune-mediated efficacy
J Control Release, 288, 161-172
DOI 10.1016/j.jconrel.2018.09.005, PubMed 30217739

Eng MS, Kaur J, Prasmickaite L, Engesæter BØ, Weyergang A, Skarpen E, Berg K, Rosenblum MG, Mælandsmo GM, Høgset A, Ferrone S, Selbo PK (2018)
Enhanced targeting of triple-negative breast carcinoma and malignant melanoma by photochemical internalization of CSPG4-targeting immunotoxins
Photochem Photobiol Sci, 17 (5), 539-551
DOI 10.1039/C7PP00358G, PubMed 29565434

Norum OJ, Fremstedal ASV, Weyergang A, Golab J, Berg K (2017)
Photochemical delivery of bleomycin induces T-cell activation of importance for curative effect and systemic anti-tumor immunity
J Control Release, 268, 120-127
DOI 10.1016/j.jconrel.2017.10.015, PubMed 29042319

Olsen CE, Weyergang A, Edwards VT, Berg K, Brech A, Weisheit S, Høgset A, Selbo PK (2017)
Development of resistance to photodynamic therapy (PDT) in human breast cancer cells is photosensitizer-dependent: Possible mechanisms and approaches for overcoming PDT-resistance
Biochem Pharmacol, 144, 63-77
DOI 10.1016/j.bcp.2017.08.002, PubMed 28784290

Bull-Hansen B, Berstad MB, Berg K, Cao Y, Skarpen E, Fremstedal AS, Rosenblum MG, Peng Q, Weyergang A (2015)
Photochemical activation of MH3-B1/rGel: a HER2-targeted treatment approach for ovarian cancer
Oncotarget, 6 (14), 12436-51
DOI 10.18632/oncotarget.3814, PubMed 26002552

Berstad MB, Cheung LH, Berg K, Peng Q, Fremstedal AS, Patzke S, Rosenblum MG, Weyergang A (2015)
Design of an EGFR-targeting toxin for photochemical delivery: in vitro and in vivo selectivity and efficacy
Oncogene, 34 (44), 5582-92
DOI 10.1038/onc.2015.15, PubMed 25684137

Bostad M, Kausberg M, Weyergang A, Olsen CE, Berg K, Høgset A, Selbo PK (2014)
Light-triggered, efficient cytosolic release of IM7-saporin targeting the putative cancer stem cell marker CD44 by photochemical internalization
Mol Pharm, 11 (8), 2764-76
DOI 10.1021/mp500129t, PubMed 24960585

Bull-Hansen B, Cao Y, Berg K, Skarpen E, Rosenblum MG, Weyergang A (2014)
Photochemical activation of the recombinant HER2-targeted fusion toxin MH3-B1/rGel; Impact of HER2 expression on treatment outcome
J Control Release, 182, 58-66
DOI 10.1016/j.jconrel.2014.03.014, PubMed 24637464

Weyergang A, Cheung LH, Rosenblum MG, Mohamedali KA, Peng Q, Waltenberger J, Berg K (2014)
Photochemical internalization augments tumor vascular cytotoxicity and specificity of VEGF(121)/rGel fusion toxin
J Control Release, 180, 1-9
DOI 10.1016/j.jconrel.2014.02.003, PubMed 24531010

Olsen CE, Berg K, Selbo PK, Weyergang A (2013)
Circumvention of resistance to photodynamic therapy in doxorubicin-resistant sarcoma by photochemical internalization of gelonin
Free Radic Biol Med, 65, 1300-1309
DOI 10.1016/j.freeradbiomed.2013.09.010, PubMed 24076428

Weyergang A, Selbo PK, Berg K (2013)
Sustained ERK [corrected] inhibition by EGFR targeting therapies is a predictive factor for synergistic cytotoxicity with PDT as neoadjuvant therapy
Biochim Biophys Acta, 1830 (3), 2659-70
DOI 10.1016/j.bbagen.2012.11.010, PubMed 23671927

Vikdal M, Weyergang A, Selbo PK, Berg K (2013)
Vascular endothelial cells as targets for photochemical internalization (PCI)
Photochem Photobiol, 89 (5), 1185-92
DOI 10.1111/php.12126, PubMed 23819771

Berstad MB, Weyergang A, Berg K (2012)
Photochemical internalization (PCI) of HER2-targeted toxins: synergy is dependent on the treatment sequence
Biochim Biophys Acta, 1820 (12), 1849-58
DOI 10.1016/j.bbagen.2012.08.027, PubMed 22981913

Selbo PK, Weyergang A, Eng MS, Bostad M, Mælandsmo GM, Høgset A, Berg K (2012)
Strongly amphiphilic photosensitizers are not substrates of the cancer stem cell marker ABCG2 and provides specific and efficient light-triggered drug delivery of an EGFR-targeted cytotoxic drug
J Control Release, 159 (2), 197-203
DOI 10.1016/j.jconrel.2012.02.003, PubMed 22349185

Weyergang A, Selbo PK, Berstad ME, Bostad M, Berg K (2011)
Photochemical internalization of tumor-targeted protein toxins
Lasers Surg Med, 43 (7), 721-33
DOI 10.1002/lsm.21084, PubMed 22057500

Selbo PK, Weyergang A, Høgset A, Norum OJ, Berstad MB, Vikdal M, Berg K (2010)
Photochemical internalization provides time- and space-controlled endolysosomal escape of therapeutic molecules
J Control Release, 148 (1), 2-12
DOI 10.1016/j.jconrel.2010.06.008, PubMed 20600406

Berg K, Weyergang A, Prasmickaite L, Bonsted A, Høgset A, Strand MT, Wagner E, Selbo PK (2010)
Photochemical internalization (PCI): a technology for drug delivery
Methods Mol Biol, 635, 133-45
DOI 10.1007/978-1-60761-697-9_10, PubMed 20552345

Weyergang A, Berg K, Kaalhus O, Peng Q, Selbo PK (2009)
Photodynamic therapy targets the mTOR signaling network in vitro and in vivo
Mol Pharm, 6 (1), 255-64
DOI 10.1021/mp800156e, PubMed 19125612

Weyergang A, Kaalhus O, Berg K (2008)
Photodynamic targeting of EGFR does not predict the treatment outcome in combination with the EGFR tyrosine kinase inhibitor Tyrphostin AG1478
Photochem Photobiol Sci, 7 (9), 1032-40
DOI 10.1039/b806209a, PubMed 18754049

Weyergang A, Kaalhus O, Berg K (2008)
Photodynamic therapy with an endocytically located photosensitizer cause a rapid activation of the mitogen-activated protein kinases extracellular signal-regulated kinase, p38, and c-Jun NH2 terminal kinase with opposing effects on cell survival
Mol Cancer Ther, 7 (6), 1740-50
DOI 10.1158/1535-7163.MCT-08-0020, PubMed 18566245

Weyergang A, Selbo PK, Berg K (2007)
Y1068 phosphorylation is the most sensitive target of disulfonated tetraphenylporphyrin-based photodynamic therapy on epidermal growth factor receptor
Biochem Pharmacol, 74 (2), 226-35
DOI 10.1016/j.bcp.2007.04.018, PubMed 17531956

Yip WL, Weyergang A, Berg K, Tønnesen HH, Selbo PK (2007)
Targeted delivery and enhanced cytotoxicity of cetuximab-saporin by photochemical internalization in EGFR-positive cancer cells
Mol Pharm, 4 (2), 241-51
DOI 10.1021/mp060105u, PubMed 17263556

Selbo PK, Weyergang A, Bonsted A, Bown SG, Berg K (2006)
Photochemical internalization of therapeutic macromolecular agents: a novel strategy to kill multidrug-resistant cancer cells
J Pharmacol Exp Ther, 319 (2), 604-12
DOI 10.1124/jpet.106.109165, PubMed 16902053

Weyergang A, Selbo PK, Berg K (2006)
Photochemically stimulated drug delivery increases the cytotoxicity and specificity of EGF-saporin
J Control Release, 111 (1-2), 165-73
DOI 10.1016/j.jconrel.2005.12.002, PubMed 16466823

Dietze A, Selbo PK, Prasmickaite L, Weyergang A, Bonsted A, Engesaeter B, Hogset A, Berg K (2006)
Photochemical internalization (PCI): a new modality for light activation of endocytosed therapeuticals
J Environ Pathol Toxicol Oncol, 25 (1-2), 521-36
DOI 10.1615/jenvironpatholtoxicoloncol.v25.i1-2.330, PubMed 16566739

Berg K, Selbo PK, Weyergang A, Dietze A, Prasmickaite L, Bonsted A, Engesaeter BØ, Angell-Petersen E, Warloe T, Frandsen N, Høgset A (2005)
Porphyrin-related photosensitizers for cancer imaging and therapeutic applications
J Microsc, 218 (Pt 2), 133-47
DOI 10.1111/j.1365-2818.2005.01471.x, PubMed 15857375

Review articles

Jerjes W, Theodossiou TA, Hirschberg H, Høgset A, Weyergang A, Selbo PK, Hamdoon Z, Hopper C, Berg K (2020)
Photochemical Internalization for Intracellular Drug Delivery. From Basic Mechanisms to Clinical Research
J Clin Med, 9 (2)
DOI 10.3390/jcm9020528, PubMed 32075165

Weyergang A, Berstad ME, Bull-Hansen B, Olsen CE, Selbo PK, Berg K (2015)
Photochemical activation of drugs for the treatment of therapy-resistant cancers
Photochem Photobiol Sci, 14 (8), 1465-75
DOI 10.1039/c5pp00029g, PubMed 25849953

Selbo PK, Bostad M, Olsen CE, Edwards VT, Høgset A, Weyergang A, Berg K (2015)
Photochemical internalisation, a minimally invasive strategy for light-controlled endosomal escape of cancer stem cell-targeting therapeutics
Photochem Photobiol Sci, 14 (8), 1433-50
DOI 10.1039/c5pp00027k, PubMed 25805311

Berg K, Berstad M, Prasmickaite L, Weyergang A, Selbo PK, Hedfors I, Høgset A (2010)
Photochemical internalization: a new tool for gene and oligonucleotide delivery
Top Curr Chem, 296, 251-81
DOI 10.1007/128_2010_63, PubMed 21504105

Norum OJ, Selbo PK, Weyergang A, Giercksky KE, Berg K (2009)
Photochemical internalization (PCI) in cancer therapy: from bench towards bedside medicine
J Photochem Photobiol B, 96 (2), 83-92
DOI 10.1016/j.jphotobiol.2009.04.012, PubMed 19467605

Berg K, Folini M, Prasmickaite L, Selbo PK, Bonsted A, Engesaeter BØ, Zaffaroni N, Weyergang A, Dietze A, Maelandsmo GM, Wagner E, Norum OJ, Høgset A (2007)
Photochemical internalization: a new tool for drug delivery
Curr Pharm Biotechnol, 8 (6), 362-72
DOI 10.2174/138920107783018354, PubMed 18289045

Berg K, Høgset A, Prasmickaite L, Weyergang A, Bonsted A, Dietze A, Lou PJ, Bown S, Norum OJ, Møllergard HM, Selbo PK (2006)
Photochemical internalization (PCI): A novel technology for activation of endocytosed therapeutic agents.
Med Laser Appl, 21, 239-251
DOI 10.1016/j.mla.2006.08.004, PublikaID 73