RSS feed

Publications by Antonia P. Sagona

35 publications found

Original articles

Sánchez Romano J, Simón-Santamaría J, McCourt P, Smedsrød B, Mortensen KE, Sagona AP, Sørensen KK, Larsen AK (2024)
Liver sinusoidal cells eliminate blood-borne phage K1F
mSphere, 9 (3), e0070223
DOI 10.1128/msphere.00702-23, PubMed 38415633

Marton HL, Bhatt A, Sagona AP, Kilbride P, Gibson MI (2023)
Screening of Hydrophilic Polymers Reveals Broad Activity in Protecting Phages during Cryopreservation
Biomacromolecules, 25 (1), 413-424
DOI 10.1021/acs.biomac.3c01042, PubMed 38124388

Williams J, Kerven J, Chen Y, Sagona AP (2023)
Genetic Engineering of Bacteriophage K1F with Human Epidermal Growth Factor to Enhance Killing of Intracellular E. coli K1
ACS Synth Biol, 12 (7), 2094-2106
DOI 10.1021/acssynbio.3c00135, PubMed 37318278

Sitthisak S, Manrueang S, Khongfak S, Leungtongkam U, Thummeepak R, Thanwisai A, Burton N, Dhanoa GK, Tsapras P, Sagona AP (2023)
Antibacterial activity of vB_AbaM_PhT2 phage hydrophobic amino acid fusion endolysin, combined with colistin against Acinetobacter baumannii
Sci Rep, 13 (1), 7470
DOI 10.1038/s41598-023-33822-8, PubMed 37156803

Marton HL, Kilbride P, Ahmad A, Sagona AP, Gibson MI (2023)
Anionic Synthetic Polymers Prevent Bacteriophage Infection
J Am Chem Soc, 145 (16), 8794-8799
DOI 10.1021/jacs.3c01874, PubMed 37067192

Williams J, Burton N, Dhanoa G, Sagona AP (2023)
Host-phage interactions and modeling for therapy
Prog Mol Biol Transl Sci, 200, 127-158
DOI 10.1016/bs.pmbts.2023.03.010, PubMed 37739552

Liyanagedera SBW, Williams J, Wheatley JP, Biketova AY, Hasan M, Sagona AP, Purdy KJ, Puxty RJ, Feher T, Kulkarni V (2022)
SpyPhage: A Cell-Free TXTL Platform for Rapid Engineering of Targeted Phage Therapies
ACS Synth Biol, 11 (10), 3330-3342
DOI 10.1021/acssynbio.2c00244, PubMed 36194543

Dhanoa GK, Kushnir I, Qimron U, Roper DI, Sagona AP (2022)
Investigating the effect of bacteriophages on bacterial FtsZ localisation
Front Cell Infect Microbiol, 12, 863712
DOI 10.3389/fcimb.2022.863712, PubMed 35967845

Styles KM, Locke RK, Cowley LA, Brown AT, Sagona AP (2022)
Transposable Element Insertions into the Escherichia coli Polysialic Acid Gene Cluster Result in Resistance to the K1F Bacteriophage
Microbiol Spectr, 10 (3), e0211221
DOI 10.1128/spectrum.02112-21, PubMed 35467398

Tsapras P, Petridi S, Chan S, Geborys M, Jacomin AC, Sagona AP, Meier P, Nezis IP (2022)
Selective autophagy controls innate immune response through a TAK1/TAB2/SH3PX1 axis
Cell Rep, 38 (4), 110286
DOI 10.1016/j.celrep.2021.110286, PubMed 35081354

Marton HL, Styles KM, Kilbride P, Sagona AP, Gibson MI (2021)
Polymer-Mediated Cryopreservation of Bacteriophages
Biomacromolecules, 22 (12), 5281-5289
DOI 10.1021/acs.biomac.1c01187, PubMed 34846863

Avramucz Á, Møller-Olsen C, Grigonyte AM, Paramalingam Y, Millard A, Sagona AP, Fehér T (2021)
Analysing Parallel Strategies to Alter the Host Specificity of Bacteriophage T7
Biology (Basel), 10 (6)
DOI 10.3390/biology10060556, PubMed 34202963

Leungtongkam U, Thummeepak R, Kitti T, Tasanapak K, Wongwigkarn J, Styles KM, Wellington EMH, Millard AD, Sagona AP, Sitthisak S (2020)
Genomic analysis reveals high virulence and antibiotic resistance amongst phage susceptible Acinetobacter baumannii
Sci Rep, 10 (1), 16154
DOI 10.1038/s41598-020-73123-y, PubMed 32999368

Møller-Olsen C, Ross T, Leppard KN, Foisor V, Smith C, Grammatopoulos DK, Sagona AP (2020)
Bacteriophage K1F targets Escherichia coli K1 in cerebral endothelial cells and influences the barrier function
Sci Rep, 10 (1), 8903
DOI 10.1038/s41598-020-65867-4, PubMed 32483257

Styles KM, Thummeepak R, Leungtongkam U, Smith SE, Christie GS, Millard A, Moat J, Dowson CG, Wellington EMH, Sitthisak S, Sagona AP (2020)
Investigating Bacteriophages Targeting the Opportunistic Pathogen Acinetobacter baumannii
Antibiotics (Basel), 9 (4)
DOI 10.3390/antibiotics9040200, PubMed 32331271

Grigonyte AM, Harrison C, MacDonald PR, Montero-Blay A, Tridgett M, Duncan J, Sagona AP, Constantinidou C, Jaramillo A, Millard A (2020)
Comparison of CRISPR and Marker-Based Methods for the Engineering of Phage T7
Viruses, 12 (2)
DOI 10.3390/v12020193, PubMed 32050613

Chang K, Kang P, Liu Y, Huang K, Miao T, Sagona AP, Nezis IP, Bodmer R, Ocorr K, Bai H (2019)
TGFB-INHB/activin signaling regulates age-dependent autophagy and cardiac health through inhibition of MTORC2
Autophagy, 16 (10), 1807-1822
DOI 10.1080/15548627.2019.1704117, PubMed 31884871

Vinner GK, Richards K, Leppanen M, Sagona AP, Malik DJ (2019)
Microencapsulation of Enteric Bacteriophages in a pH-Responsive Solid Oral Dosage Formulation Using a Scalable Membrane Emulsification Process
Pharmaceutics, 11 (9)
DOI 10.3390/pharmaceutics11090475, PubMed 31540028

Møller-Olsen C, Ho SFS, Shukla RD, Feher T, Sagona AP (2018)
Engineered K1F bacteriophages kill intracellular Escherichia coli K1 in human epithelial cells
Sci Rep, 8 (1), 17559
DOI 10.1038/s41598-018-35859-6, PubMed 30510202

Tsapras P, Sagona AP, Nezis IP (2016)
Immuno-Gold Labeling of Drosophila Follicles for Transmission Electron Microscopy
Methods Mol Biol, 1457, 97-103
DOI 10.1007/978-1-4939-3795-0_7, PubMed 27557575

Palara A, Sagona AP, Nezis IP (2016)
Preparation of Drosophila Follicles for Transmission Electron Microscopy
Methods Mol Biol, 1457, 105-10
DOI 10.1007/978-1-4939-3795-0_8, PubMed 27557576

Sagona AP, Nezis IP, Stenmark H (2014)
Association of CHMP4B and autophagy with micronuclei: implications for cataract formation
Biomed Res Int, 2014, 974393
DOI 10.1155/2014/974393, PubMed 24741567

Sagona AP, Nezis IP, Bache KG, Haglund K, Bakken AC, Skotheim RI, Stenmark H (2011)
A tumor-associated mutation of FYVE-CENT prevents its interaction with Beclin 1 and interferes with cytokinesis
PLoS One, 6 (3), e17086
DOI 10.1371/journal.pone.0017086, PubMed 21455500

Nezis IP, Shravage BV, Sagona AP, Johansen T, Baehrecke EH, Stenmark H (2010)
Autophagy as a trigger for cell death: autophagic degradation of inhibitor of apoptosis dBruce controls DNA fragmentation during late oogenesis in Drosophila
Autophagy, 6 (8), 1214-5
DOI 10.4161/auto.6.8.13694, PubMed 20935512

Nezis IP, Shravage BV, Sagona AP, Lamark T, Bjørkøy G, Johansen T, Rusten TE, Brech A, Baehrecke EH, Stenmark H (2010)
Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis
J Cell Biol, 190 (4), 523-31
DOI 10.1083/jcb.201002035, PubMed 20713604

Sagona AP, Nezis IP, Pedersen NM, Liestøl K, Poulton J, Rusten TE, Skotheim RI, Raiborg C, Stenmark H (2010)
PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody
Nat Cell Biol, 12 (4), 362-71
DOI 10.1038/ncb2036, PubMed 20208530

Nezis IP, Simonsen A, Sagona AP, Finley K, Gaumer S, Contamine D, Rusten TE, Stenmark H, Brech A (2008)
Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain
J Cell Biol, 180 (6), 1065-71
DOI 10.1083/jcb.200711108, PubMed 18347073

Review articles

Khambhati K, Bhattacharjee G, Gohil N, Dhanoa GK, Sagona AP, Mani I, Bui NL, Chu DT, Karapurkar JK, Jang SH, Chung HY, Maurya R, Alzahrani KJ, Ramakrishna S, Singh V (2022)
Phage engineering and phage-assisted CRISPR-Cas delivery to combat multidrug-resistant pathogens
Bioeng Transl Med, 8 (2), e10381
DOI 10.1002/btm2.10381, PubMed 36925687

Styles KM, Brown AT, Sagona AP (2021)
A Review of Using Mathematical Modeling to Improve Our Understanding of Bacteriophage, Bacteria, and Eukaryotic Interactions
Front Microbiol, 12, 724767
DOI 10.3389/fmicb.2021.724767, PubMed 34621252

Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM et al. (2021)
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)¹
Autophagy, 17 (1), 1-382
DOI 10.1080/15548627.2020.1797280, PubMed 33634751

Nezis IP, Sagona AP, Schink KO, Stenmark H (2010)
Divide and ProsPer: the emerging role of PtdIns3P in cytokinesis
Trends Cell Biol, 20 (11), 642-9
DOI 10.1016/j.tcb.2010.08.010, PubMed 20880709

Sagona AP, Stenmark H (2010)
Cytokinesis and cancer
FEBS Lett, 584 (12), 2652-61
DOI 10.1016/j.febslet.2010.03.044, PubMed 20371245

Other articles

Lewis JM, Sagona AP (2023)
Armed phages are heading for clinical trials
Nat Microbiol, 8 (7), 1191-1192
DOI 10.1038/s41564-023-01415-w, PubMed 37308593

Nezis IP, Shravage BV, Sagona AP, Johansen T, Baehrecke EH, Stenmark H (2010)
Autophagy as a trigger for cell death Autophagic degradation of inhibitor of apoptosis dBruce controls DNA fragmentation during late oogenesis in Drosophila
Autophagy, 6 (8), 1214-+
DOI 10.4161/auto.6.8.13694

Sagona AP, Stenmark H (2010)
Cytokinesis and cancer (vol 584, pg 2652, 2010)
FEBS Lett., 584 (18), 4128
DOI 10.1016/j.febslet.2010.08.016