Publication list - Publika - Scientific publications from Oslo University Hospital

Publications by Terhi Kärpänen

27 publications found

Original articles

Giannakopoulou E, Lehander M, Virding Culleton S, Yang W, Li Y, Karpanen T, Yoshizato T, Rustad EH, Nielsen MM, Bollineni RC, Tran TT, Delic-Sarac M, Gjerdingen TJ, Douvlataniotis K, Laos M, Ali M, Hillen A, Mazzi S, Chin DWL, Mehta A, Holm JS, Bentzen AK, Bill M, Griffioen M, Gedde-Dahl T et al. (2023)
A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo
Nat Cancer, 4 (10), 1474-1490
DOI 10.1038/s43018-023-00642-8, PubMed 37783807

Jha SK, Rauniyar K, Karpanen T, Leppänen VM, Brouillard P, Vikkula M, Alitalo K, Jeltsch M (2017)
Efficient activation of the lymphangiogenic growth factor VEGF-C requires the C-terminal domain of VEGF-C and the N-terminal domain of CCBE1
Sci Rep, 7 (1), 4916
DOI 10.1038/s41598-017-04982-1, PubMed 28687807

Karpanen T, Padberg Y, van de Pavert SA, Dierkes C, Morooka N, Peterson-Maduro J, van de Hoek G, Adrian M, Mochizuki N, Sekiguchi K, Kiefer F, Schulte D, Schulte-Merker S (2017)
An Evolutionarily Conserved Role for Polydom/Svep1 During Lymphatic Vessel Formation
Circ Res, 120 (8), 1263-1275
DOI 10.1161/CIRCRESAHA.116.308813, PubMed 28179432

Helker CS, Schuermann A, Karpanen T, Zeuschner D, Belting HG, Affolter M, Schulte-Merker S, Herzog W (2013)
The zebrafish common cardinal veins develop by a novel mechanism: lumen ensheathment
Development, 140 (13), 2776-86
DOI 10.1242/dev.091876, PubMed 23698350

Bos FL, Caunt M, Peterson-Maduro J, Planas-Paz L, Kowalski J, Karpanen T, van Impel A, Tong R, Ernst JA, Korving J, van Es JH, Lammert E, Duckers HJ, Schulte-Merker S (2011)
CCBE1 is essential for mammalian lymphatic vascular development and enhances the lymphangiogenic effect of vascular endothelial growth factor-C in vivo
Circ Res, 109 (5), 486-91
DOI 10.1161/CIRCRESAHA.111.250738, PubMed 21778431

Zheng W, Tammela T, Yamamoto M, Anisimov A, Holopainen T, Kaijalainen S, Karpanen T, Lehti K, Ylä-Herttuala S, Alitalo K (2011)
Notch restricts lymphatic vessel sprouting induced by vascular endothelial growth factor
Blood, 118 (4), 1154-62
DOI 10.1182/blood-2010-11-317800, PubMed 21566091

Karpanen T, Schulte-Merker S (2011)
Zebrafish provides a novel model for lymphatic vascular research
Methods Cell Biol, 105, 223-38
DOI 10.1016/B978-0-12-381320-6.00009-6, PubMed 21951532

Pedrioli DM, Karpanen T, Dabouras V, Jurisic G, van de Hoek G, Shin JW, Marino D, Kälin RE, Leidel S, Cinelli P, Schulte-Merker S, Brändli AW, Detmar M (2010)
miR-31 functions as a negative regulator of lymphatic vascular lineage-specific differentiation in vitro and vascular development in vivo
Mol Cell Biol, 30 (14), 3620-34
DOI 10.1128/MCB.00185-10, PubMed 20479124

Nykänen AI, Sandelin H, Krebs R, Keränen MA, Tuuminen R, Kärpänen T, Wu Y, Pytowski B, Koskinen PK, Ylä-Herttuala S, Alitalo K, Lemström KB (2010)
Targeting lymphatic vessel activation and CCL21 production by vascular endothelial growth factor receptor-3 inhibition has novel immunomodulatory and antiarteriosclerotic effects in cardiac allografts
Circulation, 121 (12), 1413-22
DOI 10.1161/CIRCULATIONAHA.109.910703, PubMed 20231530

Karpanen T, Bry M, Ollila HM, Seppänen-Laakso T, Liimatta E, Leskinen H, Kivelä R, Helkamaa T, Merentie M, Jeltsch M, Paavonen K, Andersson LC, Mervaala E, Hassinen IE, Ylä-Herttuala S, Oresic M, Alitalo K (2008)
Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy
Circ Res, 103 (9), 1018-26
DOI 10.1161/CIRCRESAHA.108.178459, PubMed 18757827

Keskitalo S, Tammela T, Lyytikka J, Karpanen T, Jeltsch M, Markkanen J, Yla-Herttuala S, Alitalo K (2007)
Enhanced capillary formation stimulated by a chimeric vascular endothelial growth factor/vascular endothelial growth factor-C silk domain fusion protein
Circ Res, 100 (10), 1460-7
DOI 10.1161/01.RES.0000269042.58594.f6, PubMed 17478734

Karpanen T, Wirzenius M, Mäkinen T, Veikkola T, Haisma HJ, Achen MG, Stacker SA, Pytowski B, Ylä-Herttuala S, Alitalo K (2006)
Lymphangiogenic growth factor responsiveness is modulated by postnatal lymphatic vessel maturation
Am J Pathol, 169 (2), 708-18
DOI 10.2353/ajpath.2006.051200, PubMed 16877368

Kärpänen T, Heckman CA, Keskitalo S, Jeltsch M, Ollila H, Neufeld G, Tamagnone L, Alitalo K (2006)
Functional interaction of VEGF-C and VEGF-D with neuropilin receptors
FASEB J, 20 (9), 1462-72
DOI 10.1096/fj.05-5646com, PubMed 16816121

Jeltsch M, Karpanen T, Strandin T, Aho K, Lankinen H, Alitalo K (2006)
Vascular endothelial growth factor (VEGF)/VEGF-C mosaic molecules reveal specificity determinants and feature novel receptor binding patterns
J Biol Chem, 281 (17), 12187-95
DOI 10.1074/jbc.M511593200, PubMed 16505489

Petrova TV, Karpanen T, Norrmén C, Mellor R, Tamakoshi T, Finegold D, Ferrell R, Kerjaschki D, Mortimer P, Ylä-Herttuala S, Miura N, Alitalo K (2004)
Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis
Nat Med, 10 (9), 974-81
DOI 10.1038/nm1094, PubMed 15322537

Uutela M, Wirzenius M, Paavonen K, Rajantie I, He Y, Karpanen T, Lohela M, Wiig H, Salven P, Pajusola K, Eriksson U, Alitalo K (2004)
PDGF-D induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis
Blood, 104 (10), 3198-204
DOI 10.1182/blood-2004-04-1485, PubMed 15271796

Laakkonen P, Akerman ME, Biliran H, Yang M, Ferrer F, Karpanen T, Hoffman RM, Ruoslahti E (2004)
Antitumor activity of a homing peptide that targets tumor lymphatics and tumor cells
Proc Natl Acad Sci U S A, 101 (25), 9381-6
DOI 10.1073/pnas.0403317101, PubMed 15197262

He Y, Kozaki K, Karpanen T, Koshikawa K, Yla-Herttuala S, Takahashi T, Alitalo K (2002)
Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling
J Natl Cancer Inst, 94 (11), 819-25
DOI 10.1093/jnci/94.11.819, PubMed 12048269

Mattila MM, Ruohola JK, Karpanen T, Jackson DG, Alitalo K, Härkönen PL (2002)
VEGF-C induced lymphangiogenesis is associated with lymph node metastasis in orthotopic MCF-7 tumors
Int J Cancer, 98 (6), 946-51
DOI 10.1002/ijc.10283, PubMed 11948478

Zhou Y, McMaster M, Woo K, Janatpour M, Perry J, Karpanen T, Alitalo K, Damsky C, Fisher SJ (2002)
Vascular endothelial growth factor ligands and receptors that regulate human cytotrophoblast survival are dysregulated in severe preeclampsia and hemolysis, elevated liver enzymes, and low platelets syndrome
Am J Pathol, 160 (4), 1405-23
DOI 10.1016/S0002-9440(10)62567-9, PubMed 11943725

Review articles

Kärpänen T (2021)
A Literature Review on Cognitive Accessibility
Stud Health Technol Inform, 282, 259-270
DOI 10.3233/SHTI210402, PubMed 34085974

Karpanen T, Olweus J (2017)
The Potential of Donor T-Cell Repertoires in Neoantigen-Targeted Cancer Immunotherapy
Front Immunol, 8, 1718
DOI 10.3389/fimmu.2017.01718, PubMed 29321773

Karpanen T, Olweus J (2015)
T-cell receptor gene therapy--ready to go viral?
Mol Oncol, 9 (10), 2019-42
DOI 10.1016/j.molonc.2015.10.006, PubMed 26548533

Karpanen T, Alitalo K (2008)
Molecular biology and pathology of lymphangiogenesis
Annu Rev Pathol, 3, 367-97
DOI 10.1146/annurev.pathmechdis.3.121806.151515, PubMed 18039141

Karpanen T, Mäkinen T (2005)
Regulation of lymphangiogenesis--from cell fate determination to vessel remodeling
Exp Cell Res, 312 (5), 575-83
DOI 10.1016/j.yexcr.2005.10.034, PubMed 16343484

He Y, Karpanen T, Alitalo K (2004)
Role of lymphangiogenic factors in tumor metastasis
Biochim Biophys Acta, 1654 (1), 3-12
DOI 10.1016/j.bbcan.2003.07.003, PubMed 14984763