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Publications by Alicia Cabezas

21 publications found

Original articles

Ribeiro JM, Canales J, Costas MJ, Cabezas A, Pinto RM, García-Díaz M, Martín-Cordero P, Cameselle JC (2023)
Genomic Distribution of Pro-Virulent cpdB-like Genes in Eubacteria and Comparison of the Enzyme Specificity of CpdB-like Proteins from Salmonella enterica, Escherichia coli and Streptococcus suis
Int J Mol Sci, 24 (4)
DOI 10.3390/ijms24044150, PubMed 36835561

Cabezas A, Costas MJ, Canales J, Pinto RM, Rodrigues JR, Ribeiro JM, Cameselle JC (2022)
Enzyme Characterization of Pro-virulent SntA, a Cell Wall-Anchored Protein of Streptococcus suis, With Phosphodiesterase Activity on cyclic-di-AMP at a Level Suited to Limit the Innate Immune System
Front Microbiol, 13, 843068
DOI 10.3389/fmicb.2022.843068, PubMed 35391727

Ribeiro JM, Costas MJ, Cabezas A, Meunier B, Onoufriadis A, Cameselle JC (2022)
The TKFC Ala185Thr variant, reported as 'null' for fructose metabolism, is fully active as triokinase
FEBS Lett, 596 (11), 1453-1457
DOI 10.1002/1873-3468.14309, PubMed 35114011

Cabezas A, López-Villamizar I, Costas MJ, Cameselle JC, Ribeiro JM (2021)
Substrate Specificity of Chimeric Enzymes Formed by Interchange of the Catalytic and Specificity Domains of the 5^'-Nucleotidase UshA and the 3^'-Nucleotidase CpdB
Molecules, 26 (8)
DOI 10.3390/molecules26082307, PubMed 33923386

López-Villamizar I, Cabezas A, Pinto RM, Canales J, Ribeiro JM, Rodrigues JR, Costas MJ, Cameselle JC (2021)
Molecular Dissection of Escherichia coli CpdB: Roles of the N Domain in Catalysis and Phosphate Inhibition, and of the C Domain in Substrate Specificity and Adenosine Inhibition
Int J Mol Sci, 22 (4)
DOI 10.3390/ijms22041977, PubMed 33671286

Rodrigues JR, Cameselle JC, Cabezas A, Ribeiro JM (2019)
Closure of the Human TKFC Active Site: Comparison of the Apoenzyme and the Complexes Formed with Either Triokinase or FMN Cyclase Substrates
Int J Mol Sci, 20 (5)
DOI 10.3390/ijms20051099, PubMed 30836629

Ribeiro JM, Canales J, Cabezas A, Rodrigues JR, Pinto RM, López-Villamizar I, Costas MJ, Cameselle JC (2018)
Specific cyclic ADP-ribose phosphohydrolase obtained by mutagenic engineering of Mn²⁺-dependent ADP-ribose/CDP-alcohol diphosphatase
Sci Rep, 8 (1), 1036
DOI 10.1038/s41598-017-18393-9, PubMed 29348648

López-Villamizar I, Cabezas A, Pinto RM, Canales J, Ribeiro JM, Cameselle JC, Costas MJ (2016)
The Characterization of Escherichia coli CpdB as a Recombinant Protein Reveals that, besides Having the Expected 3´-Nucleotidase and 2´,3´-Cyclic Mononucleotide Phosphodiesterase Activities, It Is Also Active as Cyclic Dinucleotide Phosphodiesterase
PLoS One, 11 (6), e0157308
DOI 10.1371/journal.pone.0157308, PubMed 27294396

Cabezas A, Ribeiro JM, Rodrigues JR, López-Villamizar I, Fernández A, Canales J, Pinto RM, Costas MJ, Cameselle JC (2015)
Molecular bases of catalysis and ADP-ribose preference of human Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase and conversion by mutagenesis to a preferential cyclic ADP-ribose phosphohydrolase
PLoS One, 10 (2), e0118680
DOI 10.1371/journal.pone.0118680, PubMed 25692488

Rodrigues JR, Couto A, Cabezas A, Pinto RM, Ribeiro JM, Canales J, Costas MJ, Cameselle JC (2014)
Bifunctional homodimeric triokinase/FMN cyclase: contribution of protein domains to the activities of the human enzyme and molecular dynamics simulation of domain movements
J Biol Chem, 289 (15), 10620-10636
DOI 10.1074/jbc.M113.525626, PubMed 24569995

Rodrigues JR, Fernández A, Canales J, Cabezas A, Ribeiro JM, Costas MJ, Cameselle JC (2012)
Characterization of Danio rerio Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase, the structural prototype of the ADPRibase-Mn-like protein family
PLoS One, 7 (7), e42249
DOI 10.1371/journal.pone.0042249, PubMed 22848751

Costas MJ, Pinto RM, Cordero PM, Cabezas A, Alves-Pereira I, Cameselle JC, Ribeiro JM (2010)
CGDEase, a Pseudomonas fluorescens protein of the PLC/APase superfamily with CDP-ethanolamine and (dihexanoyl)glycerophosphoethanolamine hydrolase activity induced by osmoprotectants under phosphate-deficient conditions
Mol Microbiol, 78 (6), 1556-76
DOI 10.1111/j.1365-2958.2010.07425.x, PubMed 21143324

Canales J, Fernández A, Rodrigues JR, Ferreira R, Ribeiro JM, Cabezas A, Costas MJ, Cameselle JC (2009)
Hydrolysis of the phosphoanhydride linkage of cyclic ADP-ribose by the Mn(2+)-dependent ADP-ribose/CDP-alcohol pyrophosphatase
FEBS Lett, 583 (10), 1593-8
DOI 10.1016/j.febslet.2009.04.023, PubMed 19379742

Alves-Pereira I, Canales J, Cabezas A, Cordero PM, Costas MJ, Cameselle JC (2008)
CDP-alcohol hydrolase, a very efficient activity of the 5'-nucleotidase/UDP-sugar hydrolase encoded by the ushA gene of Yersinia intermedia and Escherichia coli
J Bacteriol, 190 (18), 6153-61
DOI 10.1128/JB.00658-08, PubMed 18641143

Canales J, Fernández A, Ribeiro JM, Cabezas A, Rodrigues JR, Cameselle JC, Costas MJ (2008)
Mn2+-dependent ADP-ribose/CDP-alcohol pyrophosphatase: a novel metallophosphoesterase family preferentially expressed in rodent immune cells
Biochem J, 413 (1), 103-13
DOI 10.1042/BJ20071471, PubMed 18352857

Cabezas A, Pattni K, Stenmark H (2006)
Cloning and subcellular localization of a human phosphatidylinositol 3-phosphate 5-kinase, PIKfyve/Fab1
Gene, 371 (1), 34-41
DOI 10.1016/j.gene.2005.11.009, PubMed 16448788

Cabezas A, Costas MJ, Pinto RM, Couto A, Cameselle JC (2005)
Identification of human and rat FAD-AMP lyase (cyclic FMN forming) as ATP-dependent dihydroxyacetone kinases
Biochem Biophys Res Commun, 338 (4), 1682-9
DOI 10.1016/j.bbrc.2005.10.142, PubMed 16289032

Canales J, Cabezas A, Pinto RM, Cameselle JC (2005)
Fluorimetric HPLC detection of endogenous riboflavin 4',5'-cyclic phosphate in rat liver at nanomolar concentrations
Anal Biochem, 341 (2), 214-9
DOI 10.1016/j.ab.2005.01.060, PubMed 15907866

Cabezas A, Bache KG, Brech A, Stenmark H (2005)
Alix regulates cortical actin and the spatial distribution of endosomes
J Cell Sci, 118 (Pt 12), 2625-35
DOI 10.1242/jcs.02382, PubMed 15914539

Hoepfner S, Severin F, Cabezas A, Habermann B, Runge A, Gillooly D, Stenmark H, Zerial M (2005)
Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B
Cell, 121 (3), 437-50
DOI 10.1016/j.cell.2005.02.017, PubMed 15882625

Bache KG, Slagsvold T, Cabezas A, Rosendal KR, Raiborg C, Stenmark H (2004)
The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation
Mol Biol Cell, 15 (9), 4337-46
DOI 10.1091/mbc.e04-03-0250, PubMed 15240819