RSS feed

Publications by Agnete Brunsvik Fredriksen

21 publications found

Original articles

Kuczkowska K, Bjerkan L, Stubsrud E, Husbyn HC, Chellappa S, Hauge A, Skarshaug R, Torgersen ML, Heim JB, Jørgensen MJ, Wold CW, Schleimann MH, Tolstrup M, Granum S, Fredriksen AB, Pedersen MW, Norheim G (2023)
A novel SARS-CoV-2 Beta RBD DNA vaccine directly targeted to antigen-presenting cells induces strong humoral and T cell responses
Sci Rep, 13 (1), 18902
DOI 10.1038/s41598-023-46223-8, PubMed 37919366

Hillemanns P, Denecke A, Woelber L, Böhmer G, Jentschke M, Schjetne KW, Bruins Slot KMH, Fredriksen AB (2022)
A Therapeutic Antigen-Presenting Cell-Targeting DNA Vaccine VB10.16 in HPV16-Positive High-Grade Cervical Intraepithelial Neoplasia: Results from a Phase I/IIa Trial
Clin Cancer Res, 28 (22), 4885-4892
DOI 10.1158/1078-0432.CCR-22-1927, PubMed 36129459

Braathen R, Spång HCL, Lindeberg MM, Fossum E, Grødeland G, Fredriksen AB, Bogen B (2018)
The Magnitude and IgG Subclass of Antibodies Elicited by Targeted DNA Vaccines Are Influenced by Specificity for APC Surface Molecules
Immunohorizons, 2 (1), 38-53
DOI 10.4049/immunohorizons.1700038, PubMed 31022690

Grodeland G, Fredriksen AB, Løset GÅ, Vikse E, Fugger L, Bogen B (2016)
Antigen Targeting to Human HLA Class II Molecules Increases Efficacy of DNA Vaccination
J Immunol, 197 (9), 3575-3585
DOI 10.4049/jimmunol.1600893, PubMed 27671110

Lambert L, Kinnear E, McDonald JU, Grodeland G, Bogen B, Stubsrud E, Lindeberg MM, Fredriksen AB, Tregoning JS (2016)
DNA Vaccines Encoding Antigen Targeted to MHC Class II Induce Influenza-Specific CD8(+) T Cell Responses, Enabling Faster Resolution of Influenza Disease
Front Immunol, 7, 321
DOI 10.3389/fimmu.2016.00321, PubMed 27602032

Øynebråten I, Hinkula J, Fredriksen AB, Bogen B (2014)
Increased generation of HIV-1 gp120-reactive CD8+ T cells by a DNA vaccine construct encoding the chemokine CCL3
PLoS One, 9 (8), e104814
DOI 10.1371/journal.pone.0104814, PubMed 25122197

Grødeland G, Mjaaland S, Tunheim G, Fredriksen AB, Bogen B (2013)
The specificity of targeted vaccines for APC surface molecules influences the immune response phenotype
PLoS One, 8 (11), e80008
DOI 10.1371/journal.pone.0080008, PubMed 24244595

Grodeland G, Mjaaland S, Roux KH, Fredriksen AB, Bogen B (2013)
DNA vaccine that targets hemagglutinin to MHC class II molecules rapidly induces antibody-mediated protection against influenza
J Immunol, 191 (6), 3221-31
DOI 10.4049/jimmunol.1300504, PubMed 23956431

Frøyland M, Ruffini PA, Thompson KM, Gedde-Dahl T, Fredriksen AB, Bogen B (2011)
Targeted idiotype-fusion DNA vaccines for human multiple myeloma: preclinical testing
Eur J Haematol, 86 (5), 385-95
DOI 10.1111/j.1600-0609.2011.01590.x, PubMed 21332794

Ruffini PA, Grødeland G, Fredriksen AB, Bogen B (2010)
Human chemokine MIP1α increases efficiency of targeted DNA fusion vaccines
Vaccine, 29 (2), 191-9
DOI 10.1016/j.vaccine.2010.10.057, PubMed 21055498

Hestvik AL, Vartdal F, Fredriksen AB, Thompson KM, Kvale EO, Skorstad G, Bogen B, Holmoy T (2007)
T cells from multiple sclerosis patients recognize multiple epitopes on Self-IgG
Scand J Immunol, 66 (4), 393-401
DOI 10.1111/j.1365-3083.2007.01955.x, PubMed 17850583

Fredriksen AB, Bogen B (2007)
Chemokine-idiotype fusion DNA vaccines are potentiated by bivalency and xenogeneic sequences
Blood, 110 (6), 1797-805
DOI 10.1182/blood-2006-06-032938, PubMed 17540847

Tunheim G, Thompson KM, Fredriksen AB, Espevik T, Schjetne KW, Bogen B (2007)
Human receptors of innate immunity (CD14, TLR2) are promising targets for novel recombinant immunoglobulin-based vaccine candidates
Vaccine, 25 (24), 4723-34
DOI 10.1016/j.vaccine.2007.04.004, PubMed 17499405

Schjetne KW, Fredriksen AB, Bogen B (2007)
Delivery of antigen to CD40 induces protective immune responses against tumors
J Immunol, 178 (7), 4169-76
DOI 10.4049/jimmunol.178.7.4169, PubMed 17371973

Fredriksen AB, Sandlie I, Bogen B (2006)
DNA vaccines increase immunogenicity of idiotypic tumor antigen by targeting novel fusion proteins to antigen-presenting cells
Mol Ther, 13 (4), 776-85
DOI 10.1016/j.ymthe.2005.10.019, PubMed 16414309

Schjetne KW, Thommesen JE, Fredriksen AB, Lunde E, Sandlie I, Bogen B (2005)
Induction of central T cell tolerance: recombinant antibodies deliver peptides for deletion of antigen-specific (CD4+)8+ thymocytes
Eur J Immunol, 35 (11), 3142-52
DOI 10.1002/eji.200425947, PubMed 16184515

Holmøy T, Fredriksen AB, Thompson KM, Hestvik AL, Bogen B, Vartdal F (2005)
Cerebrospinal fluid T cell clones from patients with multiple sclerosis: recognition of idiotopes on monoclonal IgG secreted by autologous cerebrospinal fluid B cells
Eur J Immunol, 35 (6), 1786-94
DOI 10.1002/eji.200425417, PubMed 15864781

Tunheim G, Schjetne KW, Fredriksen AB, Sandlie I, Bogen B (2004)
Human CD14 is an efficient target for recombinant immunoglobulin vaccine constructs that deliver T cell epitopes
J Leukoc Biol, 77 (3), 303-10
DOI 10.1189/jlb.0804480, PubMed 15576418

Review articles

Fredriksen AB, Sandlie I, Bogen B (2012)
Targeted DNA vaccines for enhanced induction of idiotype-specific B and T cells
Front Oncol, 2, 154
DOI 10.3389/fonc.2012.00154, PubMed 23115759

Bogen B, Ruffini PA, Corthay A, Fredriksen AB, Frøyland M, Lundin K, Røsjø E, Thompson K, Massaia M (2006)
Idiotype-specific immunotherapy in multiple myeloma: suggestions for future directions of research
Haematologica, 91 (7), 941-8
PubMed 16818282

Theses

Fredriksen AB (2007)
Targeting vaccines to antigen presenting cells
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 491, 1 b. (flere pag.)
BIBSYS 070870268, ISBN 978-82-8072-699-5