Publication list - Publika - Scientific publications from Oslo University Hospital

Publications by Øygunn Aass Utheim

48 publications found

Original articles

Gundersen M, Jensen P, Nilsen C, Yazdani M, Utheim Ø, Sandås EM, Rootwelt H, Gundersen KG, Elgstøen KBP (2024)
Method Development for Omics Analyses using Schirmer Strips
Curr Eye Res, 1-9 (in press)
DOI 10.1080/02713683.2024.2335271, PubMed 38567868

Jensen P, Nilsen C, Gundersen M, Gundersen KG, Potvin R, Gazerani P, Chen X, Utheim TP, Utheim ØA (2024)
A Preservative-Free Approach - Effects on Dry Eye Signs and Symptoms After Cataract Surgery
Clin Ophthalmol, 18, 591-604
DOI 10.2147/OPTH.S446804, PubMed 38435373

Graae Jensen P, Gundersen M, Nilsen C, Gundersen KG, Potvin R, Gazerani P, Chen X, Utheim TP, Utheim ØA (2023)
Prevalence of Dry Eye Disease Among Individuals Scheduled for Cataract Surgery in a Norwegian Cataract Clinic
Clin Ophthalmol, 17, 1233-1243
DOI 10.2147/OPTH.S407805, PubMed 37138823

Pedersen HR, Gilson SJ, Landsend ECS, Utheim ØA, Utheim TP, Baraas RC (2023)
Rod and Cone Dark Adaptation in Congenital Aniridia and Its Association With Retinal Structure
Invest Ophthalmol Vis Sci, 64 (4), 18
DOI 10.1167/iovs.64.4.18, PubMed 37067366

Nilsen C, Graae Jensen P, Gundersen M, Utheim ØA, Gjerdrum B, Gundersen KG, Jahanlu D, Potvin R (2023)
The Significance of Inter-Eye Osmolarity Difference in Dry Eye Diagnostics
Clin Ophthalmol, 17, 829-835
DOI 10.2147/OPTH.S402556, PubMed 36937165

Badian RA, Utheim TP, Chen X, Utheim ØA, Ræder S, Ystenæs AE, Aakre BM, Sundling V (2021)
Meibomian gland dysfunction is highly prevalent among first-time visitors at a Norwegian dry eye specialist clinic
Sci Rep, 11 (1), 23412
DOI 10.1038/s41598-021-02738-6, PubMed 34862425

Olafsson J, Lai X, Landsend ECS, Olafsson S, Parissi E, Utheim ØA, Raeder S, Badian RA, Lagali N, Dartt DA, Utheim TP (2021)
TheraPearl Eye Mask and Blephasteam for the treatment of meibomian gland dysfunction: a randomized, comparative clinical trial
Sci Rep, 11 (1), 22386
DOI 10.1038/s41598-021-01899-8, PubMed 34789807

Chen X, Badian RA, Hynne H, Amdal CD, Herlofson BB, Utheim ØA, Westgaard KL, Fineide F, Jensen JL, Utheim TP (2021)
Alterations in meibomian glands in patients treated with intensity-modulated radiotherapy for head and neck cancer
Sci Rep, 11 (1), 22419
DOI 10.1038/s41598-021-01844-9, PubMed 34789830

Yazdani M, Fiskådal J, Chen X, Utheim ØA, Ræder S, Vitelli V, Utheim TP (2021)
Tear Film Break-Up Time and Dry Eye Disease Severity in a Large Norwegian Cohort
J Clin Med, 10 (4)
DOI 10.3390/jcm10040884, PubMed 33671667

Tellefsen Nøland S, Badian RA, Utheim TP, Utheim ØA, Stojanovic A, Tashbayev B, Raeder S, Dartt DA, Chen X (2020)
Sex and age differences in symptoms and signs of dry eye disease in a Norwegian cohort of patients
Ocul Surf, 19, 68-73
DOI 10.1016/j.jtos.2020.11.009, PubMed 33246035

Pedersen HR, Baraas RC, Landsend ECS, Utheim ØA, Utheim TP, Gilson SJ, Neitz M (2020)
PAX6 Genotypic and Retinal Phenotypic Characterization in Congenital Aniridia
Invest Ophthalmol Vis Sci, 61 (5), 14
DOI 10.1167/iovs.61.5.14, PubMed 32396632

Tashbayev B, Utheim TP, Utheim ØA, Ræder S, Jensen JL, Yazdani M, Lagali N, Vitelli V, Dartt DA, Chen X (2020)
Utility of Tear Osmolarity Measurement in Diagnosis of Dry Eye Disease
Sci Rep, 10 (1), 5542
DOI 10.1038/s41598-020-62583-x, PubMed 32218518

Tashbayev B, Garen T, Palm Ø, Chen X, Herlofson BB, Young A, Hove LH, Rykke M, Singh PB, Aqrawi LA, Utheim ØA, Utheim TP, Jensen JL (2020)
Patients with non-Sjögren's sicca report poorer general and oral health-related quality of life than patients with Sjögren's syndrome: a cross-sectional study
Sci Rep, 10 (1), 2063
DOI 10.1038/s41598-020-59078-0, PubMed 32034249

Xiao J, Adil MY, Olafsson J, Chen X, Utheim ØA, Ræder S, Lagali NS, Dartt DA, Utheim TP (2019)
Diagnostic Test Efficacy of Meibomian Gland Morphology and Function
Sci Rep, 9 (1), 17345
DOI 10.1038/s41598-019-54013-4, PubMed 31758085

Landsend ECS, Pedersen HR, Utheim ØA, Rueegg CS, Baraas RC, Lagali N, Bragadóttir R, Moe MC, Utheim TP (2019)
Characteristics and Utility of Fundus Autofluorescence in Congenital Aniridia Using Scanning Laser Ophthalmoscopy
Invest Ophthalmol Vis Sci, 60 (13), 4120-4128
DOI 10.1167/iovs.19-26994, PubMed 31574536

Xiao J, Adil MY, Chen X, Utheim ØA, Ræder S, Tønseth KA, Lagali NS, Dartt DA, Utheim TP (2019)
Functional and Morphological Evaluation of Meibomian Glands in the Assessment of Meibomian Gland Dysfunction Subtype and Severity
Am J Ophthalmol, 209, 160-167
DOI 10.1016/j.ajo.2019.09.005, PubMed 31526799

Aqrawi LA, Galtung HK, Guerreiro EM, Øvstebø R, Thiede B, Utheim TP, Chen X, Utheim ØA, Palm Ø, Skarstein K, Jensen JL (2019)
Proteomic and histopathological characterisation of sicca subjects and primary Sjögren's syndrome patients reveals promising tear, saliva and extracellular vesicle disease biomarkers
Arthritis Res Ther, 21 (1), 181
DOI 10.1186/s13075-019-1961-4, PubMed 31366407

Chen X, Aqrawi LA, Utheim TP, Tashbayev B, Utheim ØA, Reppe S, Hove LH, Herlofson BB, Singh PB, Palm Ø, Galtung HK, Jensen JCL (2019)
Elevated cytokine levels in tears and saliva of patients with primary Sjögren's syndrome correlate with clinical ocular and oral manifestations
Sci Rep, 9 (1), 7319
DOI 10.1038/s41598-019-43714-5, PubMed 31086200

Yazdani M, Chen X, Tashbayev B, Utheim ØA, Ræder S, Hua Y, Eidet JR, Stojanovic A, Dartt DA, Utheim TP (2019)
Evaluation of the Ocular Surface Disease Index Questionnaire as a Discriminative Test for Clinical Findings in Dry Eye Disease Patients
Curr Eye Res, 44 (9), 941-947
DOI 10.1080/02713683.2019.1604972, PubMed 30955380

Utheim OA, Pasovic L, Raeder S, Eidet JR, Fostad IG, Sehic A, Roald B, de la Paz MF, Lyberg T, Dartt DA, Utheim TP (2019)
Effects of explant size on epithelial outgrowth, thickness, stratification, ultrastructure and phenotype of cultured limbal epithelial cells
PLoS One, 14 (3), e0212524
DOI 10.1371/journal.pone.0212524, PubMed 30861002

Pedersen HR, Neitz M, Gilson SJ, Landsend ECS, Utheim ØA, Utheim TP, Baraas RC (2019)
The Cone Photoreceptor Mosaic in Aniridia: Within-Family Phenotype-Genotype Discordance
Ophthalmol Retina, 3 (6), 523-534
DOI 10.1016/j.oret.2019.01.020, PubMed 31174676

Adil MY, Xiao J, Olafsson J, Chen X, Lagali NS, Ræder S, Utheim ØA, Dartt DA, Utheim TP (2018)
Meibomian Gland Morphology Is a Sensitive Early Indicator of Meibomian Gland Dysfunction
Am J Ophthalmol, 200, 16-25
DOI 10.1016/j.ajo.2018.12.006, PubMed 30578784

Aqrawi LA, Chen X, Jensen JL, Morthen MK, Thiede B, Utheim ØA, Palm Ø, Tashbayev B, Utheim TP, Galtung HK (2018)
Severity of clinical dry eye manifestations influences protein expression in tear fluid of patients with primary Sjögren's syndrome
PLoS One, 13 (10), e0205762
DOI 10.1371/journal.pone.0205762, PubMed 30312344

Yazdani M, Chen X, Tashbayev B, Utheim ØA, Ræder S, Lagali N, Stojanovic A, Dartt DA, Utheim TP (2018)
Tear Production Levels and Dry Eye Disease Severity in a Large Norwegian Cohort
Curr Eye Res, 43 (12), 1465-1470
DOI 10.1080/02713683.2018.1514055, PubMed 30183390

Utheim OA, Lyberg T, Eidet JR, Raeder S, Sehic A, Roald B, Messelt E, de la Paz MF, Dartt DA, Utheim TP (2018)
Effect of Transportation on Cultured Limbal Epithelial Sheets for Worldwide Treatment of Limbal Stem Cell Deficiency
Sci Rep, 8 (1), 10502
DOI 10.1038/s41598-018-28553-0, PubMed 30002380

Landsend ECS, Utheim ØA, Pedersen HR, Aass HCD, Lagali N, Dartt DA, Baraas RC, Utheim TP (2018)
The Level of Inflammatory Tear Cytokines is Elevated in Congenital Aniridia and Associated with Meibomian Gland Dysfunction
Invest Ophthalmol Vis Sci, 59 (5), 2197-2204
DOI 10.1167/iovs.18-24027, PubMed 29801153

Pedersen HR, Hagen LA, Landsend ECS, Gilson SJ, Utheim ØA, Utheim TP, Neitz M, Baraas RC (2018)
Color Vision in Aniridia
Invest Ophthalmol Vis Sci, 59 (5), 2142-2152
DOI 10.1167/iovs.17-23047, PubMed 29801149

Landsend ECS, Pedersen HR, Utheim ØA, Xiao J, Adil MY, Tashbayev B, Lagali N, Dartt DA, Baraas RC, Utheim TP (2018)
Meibomian gland dysfunction and keratopathy are associated with dry eye disease in aniridia
Br J Ophthalmol, 103 (1), 119-124
DOI 10.1136/bjophthalmol-2017-310927, PubMed 29519880

Chen X, Utheim ØA, Xiao J, Adil MY, Stojanovic A, Tashbayev B, Jensen JL, Utheim TP (2017)
Meibomian gland features in a Norwegian cohort of patients with primary Sjögren´s syndrome
PLoS One, 12 (9), e0184284
DOI 10.1371/journal.pone.0184284, PubMed 28886085

Tashbayev B, Rusthen S, Young A, Herlofson BB, Hove LH, Singh PB, Rykke M, Aqrawi LA, Chen X, Utheim ØA, Utheim TP, Palm Ø, Jensen JL (2017)
Interdisciplinary, Comprehensive Oral and Ocular Evaluation of Patients with Primary Sjögren's Syndrome
Sci Rep, 7 (1), 10761
DOI 10.1038/s41598-017-10809-w, PubMed 28883442

Aqrawi LA, Galtung HK, Vestad B, Øvstebø R, Thiede B, Rusthen S, Young A, Guerreiro EM, Utheim TP, Chen X, Utheim ØA, Palm Ø, Jensen JL (2017)
Identification of potential saliva and tear biomarkers in primary Sjögren's syndrome, utilising the extraction of extracellular vesicles and proteomics analysis
Arthritis Res Ther, 19 (1), 14
DOI 10.1186/s13075-017-1228-x, PubMed 28122643

Utheim TP, Salvanos P, Utheim ØA, Ræder S, Pasovic L, Olstad OK, de la Paz MF, Sehic A (2016)
Transcriptome Analysis of Cultured Limbal Epithelial Cells on an Intact Amniotic Membrane following Hypothermic Storage in Optisol-GS
J Funct Biomater, 7 (1)
DOI 10.3390/jfb7010004, PubMed 26901233

Eidet JR, Utheim ØA, Islam R, Lyberg T, Messelt EB, Dartt DA, Utheim TP (2014)
The impact of storage temperature on the morphology, viability, cell number and metabolism of cultured human conjunctival epithelium
Curr Eye Res, 40 (1), 30-9
DOI 10.3109/02713683.2014.909497, PubMed 24750037

Fostad IG, Eidet JR, Shatos MA, Utheim TP, Utheim OA, Raeder S, Dartt DA (2012)
Biopsy harvesting site and distance from the explant affect conjunctival epithelial phenotype ex vivo
Exp Eye Res, 104, 15-25
DOI 10.1016/j.exer.2012.09.007, PubMed 23022405

Eidet JR, Fostad IG, Shatos MA, Utheim TP, Utheim ØA, Raeder S, Dartt DA (2012)
Effect of biopsy location and size on proliferative capacity of ex vivo expanded conjunctival tissue
Invest Ophthalmol Vis Sci, 53 (6), 2897-903
DOI 10.1167/iovs.11-8269, PubMed 22491407

Eidet JR, Utheim OA, Raeder S, Dartt DA, Lyberg T, Carreras E, Huynh TT, Messelt EB, Louch WE, Roald B, Utheim TP (2011)
Effects of serum-free storage on morphology, phenotype, and viability of ex vivo cultured human conjunctival epithelium
Exp Eye Res, 94 (1), 109-16
DOI 10.1016/j.exer.2011.11.015, PubMed 22154551

Utheim TP, Raeder S, Olstad OK, Utheim ØA, de La Paz M, Cheng R, Huynh TT, Messelt E, Roald B, Lyberg T (2009)
Comparison of the histology, gene expression profile, and phenotype of cultured human limbal epithelial cells from different limbal regions
Invest Ophthalmol Vis Sci, 50 (11), 5165-72
DOI 10.1167/iovs.08-2884, PubMed 19578011

Utheim TP, Raeder S, Utheim ØA, de la Paz M, Roald B, Lyberg T (2009)
Sterility control and long-term eye-bank storage of cultured human limbal epithelial cells for transplantation
Br J Ophthalmol, 93 (7), 980-3
DOI 10.1136/bjo.2008.149591, PubMed 19211610

Utheim ØA, Ritland JS, Utheim TP, Espeseth T, Lydersen S, Rootwelt H, Semb SO, Elsås T (2008)
Apolipoprotein E genotype and risk for development of cataract and age-related macular degeneration
Acta Ophthalmol, 86 (4), 401-3
DOI 10.1111/j.1600-0420.2007.01070.x, PubMed 18498549

Raeder S, Utheim TP, Utheim OA, Nicolaissen B, Roald B, Cai Y, Haug K, Kvalheim A, Messelt EB, Drolsum L, Reed JC, Lyberg T (2007)
Effects of organ culture and Optisol-GS storage on structural integrity, phenotypes, and apoptosis in cultured corneal epithelium
Invest Ophthalmol Vis Sci, 48 (12), 5484-93
DOI 10.1167/iovs.07-0494, PubMed 18055796

Ritland JS, Utheim TP, Utheim OA, Espeseth T, Lydersen S, Semb SO, Rootwelt H, Elsås T (2007)
Effects of APOE and CHRNA4 genotypes on retinal nerve fibre layer thickness at the optic disc and on risk for developing exfoliation syndrome
Acta Ophthalmol Scand, 85 (3), 257-61
DOI 10.1111/j.1600-0420.2006.00824.x, PubMed 17488453

Raeder S, Utheim TP, Utheim OA, Cai Y, Roald B, Lyberg T, Kjeldsen-Kragh J, Ramstad H, Messelt E, Nicolaissen B (2007)
Effect of limbal explant orientation on the histology, phenotype, ultrastructure and barrier function of cultured limbal epithelial cells
Acta Ophthalmol Scand, 85 (4), 377-86
DOI 10.1111/j.1600-0420.2006.00873.x, PubMed 17263847

Review articles

Yazdani M, Elgstøen KBP, Rootwelt H, Shahdadfar A, Utheim ØA, Utheim TP (2019)
Tear Metabolomics in Dry Eye Disease: A Review
Int J Mol Sci, 20 (15)
DOI 10.3390/ijms20153755, PubMed 31374809

Landsend ES, Utheim ØA, Pedersen HR, Lagali N, Baraas RC, Utheim TP (2017)
The genetics of congenital aniridia-a guide for the ophthalmologist
Surv Ophthalmol, 63 (1), 105-113
DOI 10.1016/j.survophthal.2017.09.004, PubMed 28923585

Utheim TP, Utheim ØA, Khan QE, Sehic A (2016)
Culture of Oral Mucosal Epithelial Cells for the Purpose of Treating Limbal Stem Cell Deficiency
J Funct Biomater, 7 (1)
DOI 10.3390/jfb7010005, PubMed 26938569

Sehic A, Utheim ØA, Ommundsen K, Utheim TP (2015)
Pre-Clinical Cell-Based Therapy for Limbal Stem Cell Deficiency
J Funct Biomater, 6 (3), 863-88
DOI 10.3390/jfb6030863, PubMed 26343740