Publication list - Publika - Scientific publications from Oslo University Hospital

Publications by Rosmarie Friemann

38 publications found

Original articles

Currie MJ, Davies JS, Scalise M, Gulati A, Wright JD, Newton-Vesty MC, Abeysekera GS, Subramanian R, Wahlgren WY, Friemann R, Allison JR, Mace PD, Griffin MDW, Demeler B, Wakatsuki S, Drew D, Indiveri C, Dobson RCJ, North RA (2024)
Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter
Elife, 12
DOI 10.7554/eLife.92307, PubMed 38349818

Davies JS, Currie MJ, North RA, Scalise M, Wright JD, Copping JM, Remus DM, Gulati A, Morado DR, Jamieson SA, Newton-Vesty MC, Abeysekera GS, Ramaswamy S, Friemann R, Wakatsuki S, Allison JR, Indiveri C, Drew D, Mace PD, Dobson RCJ (2023)
Structure and mechanism of a tripartite ATP-independent periplasmic TRAP transporter
Nat Commun, 14 (1), 1120
DOI 10.1038/s41467-023-36590-1, PubMed 36849793

Bozzola T, Scalise M, Larsson CU, Newton-Vesty MC, Rovegno C, Mitra A, Cramer J, Wahlgren WY, Radhakrishnan Santhakumari P, Johnsson RE, Schwardt O, Ernst B, Friemann R, Dobson RCJ, Indiveri C, Schelin J, Nilsson UJ, Ellervik U (2022)
Sialic Acid Derivatives Inhibit SiaT Transporters and Delay Bacterial Growth
ACS Chem Biol, 17 (7), 1890-1900
DOI 10.1021/acschembio.2c00321, PubMed 35675124

Currie MJ, Manjunath L, Horne CR, Rendle PM, Subramanian R, Friemann R, Fairbanks AJ, Muscroft-Taylor AC, North RA, Dobson RCJ (2021)
N-acetylmannosamine-6-phosphate 2-epimerase uses a novel substrate-assisted mechanism to catalyze amino sugar epimerization
J Biol Chem, 297 (4), 101113
DOI 10.1016/j.jbc.2021.101113, PubMed 34437902

Horne CR, Venugopal H, Panjikar S, Wood DM, Henrickson A, Brookes E, North RA, Murphy JM, Friemann R, Griffin MDW, Ramm G, Demeler B, Dobson RCJ (2021)
Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism
Nat Commun, 12 (1), 1988
DOI 10.1038/s41467-021-22253-6, PubMed 33790291

Coombes D, Davies JS, Newton-Vesty MC, Horne CR, Setty TG, Subramanian R, Moir JWB, Friemann R, Panjikar S, Griffin MDW, North RA, Dobson RCJ (2020)
The basis for non-canonical ROK family function in the N-acetylmannosamine kinase from the pathogen Staphylococcus aureus
J Biol Chem, 295 (10), 3301-3315
DOI 10.1074/jbc.RA119.010526, PubMed 31949045

Sainas S, Pippione AC, Lupino E, Giorgis M, Circosta P, Gaidano V, Goyal P, Bonanni D, Rolando B, Cignetti A, Ducime A, Andersson M, Järvå M, Friemann R, Piccinini M, Ramondetti C, Buccinnà B, Al-Karadaghi S, Boschi D, Saglio G, Lolli ML (2019)
Correction to Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors
J Med Chem, 62 (3), 1696
DOI 10.1021/acs.jmedchem.9b00057, PubMed 30694669

Lolli ML, Carnovale IM, Pippione AC, Wahlgren WY, Bonanni D, Marini E, Zonari D, Gallicchio M, Boscaro V, Goyal P, Friemann R, Rolando B, Bagnati R, Adinolfi S, Oliaro-Bosso S, Boschi D (2019)
Bioisosteres of Indomethacin as Inhibitors of Aldo-Keto Reductase 1C3
ACS Med Chem Lett, 10 (4), 437-443
DOI 10.1021/acsmedchemlett.8b00484, PubMed 30996776

Bisignano P, Ghezzi C, Jo H, Polizzi NF, Althoff T, Kalyanaraman C, Friemann R, Jacobson MP, Wright EM, Grabe M (2018)
Inhibitor binding mode and allosteric regulation of Na⁺-glucose symporters
Nat Commun, 9 (1), 5245
DOI 10.1038/s41467-018-07700-1, PubMed 30532032

Davies JS, Coombes D, Horne CR, Pearce FG, Friemann R, North RA, Dobson RCJ (2018)
Functional and solution structure studies of amino sugar deacetylase and deaminase enzymes from Staphylococcus aureus
FEBS Lett, 593 (1), 52-66
DOI 10.1002/1873-3468.13289, PubMed 30411345

Pippione AC, Sainas S, Goyal P, Fritzson I, Cassiano GC, Giraudo A, Giorgis M, Tavella TA, Bagnati R, Rolando B, Caing-Carlsson R, Costa FTM, Andrade CH, Al-Karadaghi S, Boschi D, Friemann R, Lolli ML (2018)
Hydroxyazole scaffold-based Plasmodium falciparum dihydroorotate dehydrogenase inhibitors: Synthesis, biological evaluation and X-ray structural studies
Eur J Med Chem, 163, 266-280
DOI 10.1016/j.ejmech.2018.11.044, PubMed 30529545

Sainas S, Pippione AC, Lupino E, Giorgis M, Circosta P, Gaidano V, Goyal P, Bonanni D, Rolando B, Cignetti A, Ducime A, Andersson M, Järvå M, Friemann R, Piccinini M, Ramondetti C, Buccinnà B, Al-Karadaghi S, Boschi D, Saglio G, Lolli ML (2018)
Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors
J Med Chem, 61 (14), 6034-6055
DOI 10.1021/acs.jmedchem.8b00373, PubMed 29939742

North RA, Wahlgren WY, Remus DM, Scalise M, Kessans SA, Dunevall E, Claesson E, Soares da Costa TP, Perugini MA, Ramaswamy S, Allison JR, Indiveri C, Friemann R, Dobson RCJ (2018)
The Sodium Sialic Acid Symporter From Staphylococcus aureus Has Altered Substrate Specificity
Front Chem, 6, 233
DOI 10.3389/fchem.2018.00233, PubMed 30023356

Wahlgren WY, Dunevall E, North RA, Paz A, Scalise M, Bisignano P, Bengtsson-Palme J, Goyal P, Claesson E, Caing-Carlsson R, Andersson R, Beis K, Nilsson UJ, Farewell A, Pochini L, Indiveri C, Grabe M, Dobson RCJ, Abramson J, Ramaswamy S, Friemann R (2018)
Substrate-bound outward-open structure of a Na⁺-coupled sialic acid symporter reveals a new Na⁺ site
Nat Commun, 9 (1), 1753
DOI 10.1038/s41467-018-04045-7, PubMed 29717135

Pippione AC, Carnovale IM, Bonanni D, Sini M, Goyal P, Marini E, Pors K, Adinolfi S, Zonari D, Festuccia C, Wahlgren WY, Friemann R, Bagnati R, Boschi D, Oliaro-Bosso S, Lolli ML (2018)
Potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the benzoisoxazole moiety: application of a bioisosteric scaffold hopping approach to flufenamic acid
Eur J Med Chem, 150, 930-945
DOI 10.1016/j.ejmech.2018.03.040, PubMed 29602039

Bairy S, Gopalan LN, Setty TG, Srinivasachari S, Manjunath L, Kumar JP, Guntupalli SR, Bose S, Nayak V, Ghosh S, Sathyanarayanan N, Caing-Carlsson R, Wahlgren WY, Friemann R, Ramaswamy S, Neerathilingam M (2018)
Automation aided optimization of cloning, expression and purification of enzymes of the bacterial sialic acid catabolic and sialylation pathways enzymes for structural studies
Microb Biotechnol, 11 (2), 420-428
DOI 10.1111/1751-7915.13041, PubMed 29345069

Wollman AJ, Shashkova S, Hedlund EG, Friemann R, Hohmann S, Leake MC (2017)
Transcription factor clusters regulate genes in eukaryotic cells
Elife, 6
DOI 10.7554/eLife.27451, PubMed 28841133

Caing-Carlsson R, Goyal P, Sharma A, Ghosh S, Setty TG, North RA, Friemann R, Ramaswamy S (2017)
Crystal structure of N-acetylmannosamine kinase from Fusobacterium nucleatum
Acta Crystallogr F Struct Biol Commun, 73 (Pt 6), 356-362
DOI 10.1107/S2053230X17007439, PubMed 28580924

Sainas S, Pippione AC, Giorgis M, Lupino E, Goyal P, Ramondetti C, Buccinnà B, Piccinini M, Braga RC, Andrade CH, Andersson M, Moritzer AC, Friemann R, Mensa S, Al-Kadaraghi S, Boschi D, Lolli ML (2017)
Design, synthesis, biological evaluation and X-ray structural studies of potent human dihydroorotate dehydrogenase inhibitors based on hydroxylated azole scaffolds
Eur J Med Chem, 129, 287-302
DOI 10.1016/j.ejmech.2017.02.017, PubMed 28235702

Eriksson UK, Fischer G, Friemann R, Enkavi G, Tajkhorshid E, Neutze R (2013)
Subangstrom resolution X-ray structure details aquaporin-water interactions
Science, 340 (6138), 1346-1349
DOI 10.1126/science.1234306, PubMed 23766328

Allerbring EB, Duru AD, Uchtenhagen H, Madhurantakam C, Tomek MB, Grimm S, Mazumdar PA, Friemann R, Uhlin M, Sandalova T, Nygren PÅ, Achour A (2012)
Unexpected T-cell recognition of an altered peptide ligand is driven by reversed thermodynamics
Eur J Immunol, 42 (11), 2990-3000
DOI 10.1002/eji.201242588, PubMed 22837158

Talavera A, Mackenzie J, Garrido G, Friemann R, López-Requena A, Moreno E, Krengel U (2011)
Structure of the Fab fragment of the anti-murine EGFR antibody 7A7 and exploration of its receptor binding site
Mol Immunol, 48 (12-13), 1578-85
DOI 10.1016/j.molimm.2011.03.016, PubMed 21592580

Uchtenhagen H, Friemann R, Raszewski G, Spetz AL, Nilsson L, Achour A (2011)
Crystal structure of the HIV-2 neutralizing Fab fragment 7C8 with high specificity to the V3 region of gp125
PLoS One, 6 (4), e18767
DOI 10.1371/journal.pone.0018767, PubMed 21541316

Friemann R, Larsson DS, Wang Y, van der Spoel D (2009)
Molecular dynamics simulations of a membrane protein-micelle complex in vacuo
J Am Chem Soc, 131 (46), 16606-7
DOI 10.1021/ja902962y, PubMed 19877613

Talavera A, Friemann R, Gómez-Puerta S, Martinez-Fleites C, Garrido G, Rabasa A, López-Requena A, Pupo A, Johansen RF, Sánchez O, Krengel U, Moreno E (2009)
Nimotuzumab, an antitumor antibody that targets the epidermal growth factor receptor, blocks ligand binding while permitting the active receptor conformation
Cancer Res, 69 (14), 5851-9
DOI 10.1158/0008-5472.CAN-08-4518, PubMed 19584289

Uchtenhagen H, Sourial S, Friemann R, Ehnlund M, Spetz AL, Harris RA, Madhurantakam C, Achour A (2009)
Production, purification, crystallization and preliminary X-ray diffraction analysis of the HIV-2-neutralizing V3 loop-specific Fab fragment 7C8
Acta Crystallogr Sect F Struct Biol Cryst Commun, 65 (Pt 7), 705-8
DOI 10.1107/S1744309109020685, PubMed 19574645

Friemann R, Lee K, Brown EN, Gibson DT, Eklund H, Ramaswamy S (2008)
Structures of the multicomponent Rieske non-heme iron toluene 2,3-dioxygenase enzyme system
Acta Crystallogr D Biol Crystallogr, 65 (Pt 1), 24-33
DOI 10.1107/S0907444908036524, PubMed 19153463

Brown EN, Friemann R, Karlsson A, Parales JV, Couture MM, Eltis LD, Ramaswamy S (2008)
Determining Rieske cluster reduction potentials
J Biol Inorg Chem, 13 (8), 1301-13
DOI 10.1007/s00775-008-0413-4, PubMed 18719951

Dai S, Friemann R, Glauser DA, Bourquin F, Manieri W, Schürmann P, Eklund H (2007)
Structural snapshots along the reaction pathway of ferredoxin-thioredoxin reductase
Nature, 448 (7149), 92-6
DOI 10.1038/nature05937, PubMed 17611542

Lee KS, Parales JV, Friemann R, Parales RE (2005)
Active site residues controlling substrate specificity in 2-nitrotoluene dioxygenase from Acidovorax sp. strain JS42
J Ind Microbiol Biotechnol, 32 (10), 465-73
DOI 10.1007/s10295-005-0021-z, PubMed 16175409

Parales RE, Huang R, Yu CL, Parales JV, Lee FK, Lessner DJ, Ivkovic-Jensen MM, Liu W, Friemann R, Ramaswamy S, Gibson DT (2005)
Purification, characterization, and crystallization of the components of the nitrobenzene and 2-nitrotoluene dioxygenase enzyme systems
Appl Environ Microbiol, 71 (7), 3806-14
DOI 10.1128/AEM.71.7.3806-3814.2005, PubMed 16000792

Lee K, Friemann R, Parales JV, Gibson DT, Ramaswamy S (2005)
Purification, crystallization and preliminary X-ray diffraction studies of the three components of the toluene 2,3-dioxygenase enzyme system
Acta Crystallogr Sect F Struct Biol Cryst Commun, 61 (Pt 7), 669-72
DOI 10.1107/S1744309105017549, PubMed 16511124

Friemann R, Ivkovic-Jensen MM, Lessner DJ, Yu CL, Gibson DT, Parales RE, Eklund H, Ramaswamy S (2005)
Structural insight into the dioxygenation of nitroarene compounds: the crystal structure of nitrobenzene dioxygenase
J Mol Biol, 348 (5), 1139-51
DOI 10.1016/j.jmb.2005.03.052, PubMed 15854650

Friemann R, Schmidt H, Ramaswamy S, Forstner M, Krauth-Siegel RL, Eklund H (2003)
Structure of thioredoxin from Trypanosoma brucei brucei
FEBS Lett, 554 (3), 301-5
DOI 10.1016/s0014-5793(03)01173-6, PubMed 14623083

Johansson K, El-Ahmad M, Friemann R, Jörnvall H, Markovic O, Eklund H (2002)
Crystal structure of plant pectin methylesterase
FEBS Lett, 514 (2-3), 243-9
DOI 10.1016/s0014-5793(02)02372-4, PubMed 11943159

Review articles

North RA, Horne CR, Davies JS, Remus DM, Muscroft-Taylor AC, Goyal P, Wahlgren WY, Ramaswamy S, Friemann R, Dobson RCJ (2017)
"Just a spoonful of sugar...": import of sialic acid across bacterial cell membranes
Biophys Rev, 10 (2), 219-227
DOI 10.1007/s12551-017-0343-x, PubMed 29222808