Publications by Geir Christensen
226 publications found
Original articles
Temporal expression and spatial distribution of the proteoglycan versican during cardiac fibrosis development
Matrix Biol Plus, 19-20, 100135
DOI 10.1016/j.mbplus.2023.100135, PubMed 38076279
Inhibition of the extracellular enzyme A disintegrin and metalloprotease with thrombospondin motif 4 prevents cardiac fibrosis and dysfunction
Cardiovasc Res, 119 (10), 1915-1927
DOI 10.1093/cvr/cvad078, PubMed 37216909
BIN1, Myotubularin, and Dynamin-2 Coordinate T-Tubule Growth in Cardiomyocytes
Circ Res, 132 (11), e188-e205
DOI 10.1161/CIRCRESAHA.122.321732, PubMed 37139790
Beneficial effects of exercise initiated before development of hypertrophic cardiomyopathy in genotype-positive mice
Am J Physiol Heart Circ Physiol, 324 (6), H881-H892
DOI 10.1152/ajpheart.00701.2022, PubMed 37115627
Inflammation and Syndecan-4 Shedding from Cardiac Cells in Ischemic and Non-Ischemic Heart Disease
Biomedicines, 11 (4)
DOI 10.3390/biomedicines11041066, PubMed 37189684
Cardiac Troponin T and NT-proBNP for Prediction of 30-Day Readmission or Death in Patients with Acute Dyspnea: Data from the Akershus Cardiac Examination 2 Study
Cardiology, 148 (6), 506-516
DOI 10.1159/000533266, PubMed 37544298
ADAMTSL3 knock-out mice develop cardiac dysfunction and dilatation with increased TGFβ signalling after pressure overload
Commun Biol, 5 (1), 1392
DOI 10.1038/s42003-022-04361-1, PubMed 36539599
Lumican accumulates with fibrillar collagen in fibrosis in hypertrophic cardiomyopathy
ESC Heart Fail, 10 (2), 858-871
DOI 10.1002/ehf2.14234, PubMed 36444917
Calcineurin-NFAT dynamics correspond to cardiac remodeling during aortic banding and debanding, mimicking aortic valve replacement
Front Mol Med, 2, 1-14
DOI 10.3389/fmmed.2022.980717, PublikaID 435
Cardiomyocyte-specific overexpression of syndecan-4 in mice results in activation of calcineurin-NFAT signalling and exacerbated cardiac hypertrophy
Mol Biol Rep, 49 (12), 11795-11809
DOI 10.1007/s11033-022-07985-y, PubMed 36205855
The female syndecan-4-/- heart has smaller cardiomyocytes, augmented insulin/pSer473-Akt/pSer9-GSK-3β signaling, and lowered SCOP, pThr308-Akt/Akt and GLUT4 levels
Front Cell Dev Biol, 10, 908126
DOI 10.3389/fcell.2022.908126, PubMed 36092718
Integrin α11β1 and syndecan-4 dual receptor ablation attenuate cardiac hypertrophy in the pressure overloaded heart
Am J Physiol Heart Circ Physiol, 322 (6), H1057-H1071
DOI 10.1152/ajpheart.00635.2021, PubMed 35522553
Prognostic value of cardiac biomarkers and National Early Warning Score 2 in acute dyspnoea
Open Heart, 9 (1)
DOI 10.1136/openhrt-2021-001938, PubMed 35387863
Extreme altitude induces divergent mass reduction of right and left ventricle in mountain climbers
Physiol Rep, 10 (3), e15184
DOI 10.14814/phy2.15184, PubMed 35146955
AKAP18δ Anchors and Regulates CaMKII Activity at Phospholamban-SERCA2 and RYR
Circ Res, 130 (1), 27-44
DOI 10.1161/CIRCRESAHA.120.317976, PubMed 34814703
Biological variation of secretoneurin; a novel cardiovascular biomarker implicated in arrhythmogenesis
Clin Biochem, 98, 74-77
DOI 10.1016/j.clinbiochem.2021.09.014, PubMed 34624255
The extracellular matrix glycoprotein ADAMTSL2 is increased in heart failure and inhibits TGFβ signalling in cardiac fibroblasts
Sci Rep, 11 (1), 19757
DOI 10.1038/s41598-021-99032-2, PubMed 34611183
Circulating MicroRNA-210 Concentrations in Patients with Acute Heart Failure: Data from the Akershus Cardiac Examination 2 Study
Clin Chem, 67 (6), 889-898
DOI 10.1093/clinchem/hvab030, PubMed 33783502
Sacubitril/valsartan ameliorates cardiac hypertrophy and preserves diastolic function in cardiac pressure overload
ESC Heart Fail, 8 (2), 918-927
DOI 10.1002/ehf2.13177, PubMed 33497525
Performance of a Novel Research-Use-Only Secretoneurin ELISA in Patients with Suspected Acute Coronary Syndrome: Comparison with an Established Secretoneurin Radioimmunoassay
Cardiology, 146 (5), 566-574
DOI 10.1159/000517444, PubMed 34284402
High-sensitivity cardiac troponin T and N-terminal pro-B-type natriuretic peptide in acute heart failure: Data from the ACE 2 study
Clin Biochem, 88, 30-36
DOI 10.1016/j.clinbiochem.2020.11.009, PubMed 33245872
The Cardiac Syndecan-2 Interactome
Front Cell Dev Biol, 8, 792
DOI 10.3389/fcell.2020.00792, PubMed 32984315
Syndecan-4-/- Mice Have Smaller Muscle Fibers, Increased Akt/mTOR/S6K1 and Notch/HES-1 Pathways, and Alterations in Extracellular Matrix Components
Front Cell Dev Biol, 8, 730
DOI 10.3389/fcell.2020.00730, PubMed 32850844
Generation of a novel mouse strain with fibroblast-specific expression of Cre recombinase
Matrix Biol Plus, 8, 100045
DOI 10.1016/j.mbplus.2020.100045, PubMed 33543038
Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin
J Am Heart Assoc, 9 (3), e013518
DOI 10.1161/JAHA.119.013518, PubMed 32000579
Moderate Loss of the Extracellular Matrix Proteoglycan Lumican Attenuates Cardiac Fibrosis in Mice Subjected to Pressure Overload
Cardiology, 145 (3), 187-198
DOI 10.1159/000505318, PubMed 31968347
The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload
Sci Rep, 9 (1), 9206
DOI 10.1038/s41598-019-45651-9, PubMed 31235849
Circulating secretoneurin concentrations in patients with moderate to severe aortic stenosis
Clin Biochem, 71, 17-23
DOI 10.1016/j.clinbiochem.2019.06.008, PubMed 31228433
Circulating Secretoneurin Concentrations After Cardiac Surgery: Data From the FINNish Acute Kidney Injury Heart Study
Crit Care Med, 47 (5), e412-e419
DOI 10.1097/CCM.0000000000003670, PubMed 30730440
The cardiac syndecan-4 interactome reveals a role for syndecan-4 in nuclear translocation of muscle LIM protein (MLP)
J Biol Chem, 294 (22), 8717-8731
DOI 10.1074/jbc.RA118.006423, PubMed 30967474
Secretoneurin Is an Endogenous Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor That Attenuates Ca2+-Dependent Arrhythmia
Circ Arrhythm Electrophysiol, 12 (4), e007045
DOI 10.1161/CIRCEP.118.007045, PubMed 30943765
Caspase-1 induces smooth muscle cell growth in hypoxia-induced pulmonary hypertension
Am J Physiol Lung Cell Mol Physiol, 316 (6), L999-L1012
DOI 10.1152/ajplung.00322.2018, PubMed 30908936
Regional diastolic dysfunction in post-infarction heart failure: role of local mechanical load and SERCA expression
Cardiovasc Res, 115 (4), 752-764
DOI 10.1093/cvr/cvy257, PubMed 30351410
Cardiomyocyte substructure reverts to an immature phenotype during heart failure
J Physiol, 597 (7), 1833-1853
DOI 10.1113/JP277273, PubMed 30707448
STIM1 R304W causes muscle degeneration and impaired platelet activation in mice
Cell Calcium, 76, 87-100
DOI 10.1016/j.ceca.2018.10.001, PubMed 30390422
A novel method for high precision aortic constriction that allows for generation of specific cardiac phenotypes in mice
Cardiovasc Res, 114 (12), 1680-1690
DOI 10.1093/cvr/cvy141, PubMed 29878127
Prognostic and diagnostic significance of mid-regional pro-atrial natriuretic peptide in acute exacerbation of chronic obstructive pulmonary disease and acute heart failure: data from the ACE 2 Study
Biomarkers, 23 (7), 654-663
DOI 10.1080/1354750X.2018.1474258, PubMed 29733687
The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling
PLoS One, 13 (7), e0201422
DOI 10.1371/journal.pone.0201422, PubMed 30052659
Diagnostic and prognostic properties of procalcitonin in patients with acute dyspnea: Data from the ACE 2 Study
Clin Biochem, 59, 62-68
DOI 10.1016/j.clinbiochem.2018.07.006, PubMed 30028971
Prognostic Value of Secretoneurin in Patients With Severe Sepsis and Septic Shock: Data From the Albumin Italian Outcome Sepsis Study
Crit Care Med, 46 (5), e404-e410
DOI 10.1097/CCM.0000000000003050, PubMed 29481425
Sweet, yet underappreciated: Proteoglycans and extracellular matrix remodeling in heart disease
Matrix Biol, 75-76, 286-299
DOI 10.1016/j.matbio.2018.01.001, PubMed 29337052
Prognostic and diagnostic significance of copeptin in acute exacerbation of chronic obstructive pulmonary disease and acute heart failure: data from the ACE 2 study
Respir Res, 18 (1), 184
DOI 10.1186/s12931-017-0665-z, PubMed 29100503
Fibroblast growth factor 23 in patients with acute dyspnea: Data from the Akershus Cardiac Examination (ACE) 2 Study
Clin Biochem, 52, 41-47
DOI 10.1016/j.clinbiochem.2017.10.015, PubMed 29074091
Overexpression of integrin α11 induces cardiac fibrosis in mice
Acta Physiol (Oxf), 222 (2)
DOI 10.1111/apha.12932, PubMed 28771943
Wnt5a is associated with right ventricular dysfunction and adverse outcome in dilated cardiomyopathy
Sci Rep, 7 (1), 3490
DOI 10.1038/s41598-017-03625-9, PubMed 28615692
The Notch Ligands DLL1 and Periostin Are Associated with Symptom Severity and Diastolic Function in Dilated Cardiomyopathy
J Cardiovasc Transl Res, 10 (4), 401-410
DOI 10.1007/s12265-017-9748-y, PubMed 28474304
Wnt5a is elevated in heart failure and affects cardiac fibroblast function
J Mol Med (Berl), 95 (7), 767-777
DOI 10.1007/s00109-017-1529-1, PubMed 28357477
Glycosylated Chromogranin A in Heart Failure: Implications for Processing and Cardiomyocyte Calcium Homeostasis
Circ Heart Fail, 10 (2)
DOI 10.1161/CIRCHEARTFAILURE.116.003675, PubMed 28209766
Mid-regional pro-adrenomedullin in patients with acute dyspnea: Data from the Akershus Cardiac Examination (ACE) 2 Study
Clin Biochem, 50 (7-8), 394-400
DOI 10.1016/j.clinbiochem.2016.12.010, PubMed 28065681
Circulating chromogranin B levels in patients with acute respiratory failure: data from the FINNALI Study
Biomarkers, 22 (8), 775-781
DOI 10.1080/1354750X.2016.1269200, PubMed 28049363
NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture
Cell Rep, 18 (1), 82-92
DOI 10.1016/j.celrep.2016.12.009, PubMed 28052262
Toll-Like Receptor 9 Promotes Survival in SERCA2a KO Heart Failure Mice
Mediators Inflamm, 2017, 9450439
DOI 10.1155/2017/9450439, PubMed 28490840
The Heparan Sulfate Proteoglycan Glypican-6 Is Upregulated in the Failing Heart, and Regulates Cardiomyocyte Growth through ERK1/2 Signaling
PLoS One, 11 (10), e0165079
DOI 10.1371/journal.pone.0165079, PubMed 27768722
Prognostic Value of Secretoneurin in Critically Ill Patients With Infections
Crit Care Med, 44 (10), 1882-90
DOI 10.1097/CCM.0000000000001832, PubMed 27414477
Prognostic Value of Secretoneurin in Patients with Acute Respiratory Failure: Data from the FINNALI Study
Clin Chem, 62 (10), 1380-9
DOI 10.1373/clinchem.2016.258764, PubMed 27540029
Prevalence and Prognostic Significance of Hyponatremia in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Data from the Akershus Cardiac Examination (ACE) 2 Study
PLoS One, 11 (8), e0161232
DOI 10.1371/journal.pone.0161232, PubMed 27529844
The influence of heart failure co-morbidity on high-sensitivity troponin T levels in COPD exacerbation in a prospective cohort study: data from the Akershus cardiac examination (ACE) 2 study
Biomarkers, 21 (2), 173-9
DOI 10.3109/1354750X.2015.1126645, PubMed 26754170
Seasonal variation in accumulation of persistent organic pollutants in an Arctic marine benthic food web
Sci Total Environ, 542 (Pt A), 108-20
DOI 10.1016/j.scitotenv.2015.10.092, PubMed 26519572
[Diagnostic accuracy for heart failure – data from the Akershus Cardiac Examination 2 Study]
Tidsskr Nor Laegeforen, 135 (19), 1738-44
DOI 10.4045/tidsskr.14.1174, PubMed 26486668
Sustained Toll-Like Receptor 9 Activation Promotes Systemic and Cardiac Inflammation, and Aggravates Diastolic Heart Failure in SERCA2a KO Mice
PLoS One, 10 (10), e0139715
DOI 10.1371/journal.pone.0139715, PubMed 26461521
Shedding of syndecan-4 promotes immune cell recruitment and mitigates cardiac dysfunction after lipopolysaccharide challenge in mice
J Mol Cell Cardiol, 88, 133-44
DOI 10.1016/j.yjmcc.2015.10.003, PubMed 26449522
Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure
Nat Commun, 6, 7229
DOI 10.1038/ncomms8229, PubMed 26068603
Absence of the inflammasome adaptor ASC reduces hypoxia-induced pulmonary hypertension in mice
Am J Physiol Lung Cell Mol Physiol, 309 (4), L378-87
DOI 10.1152/ajplung.00342.2014, PubMed 26071556
Influence of glycosylation on diagnostic and prognostic accuracy of N-terminal pro-B-type natriuretic peptide in acute dyspnea: data from the Akershus Cardiac Examination 2 Study
Clin Chem, 61 (8), 1087-97
DOI 10.1373/clinchem.2015.239673, PubMed 26056354
Current status, between-year comparisons and maternal transfer of organohalogenated compounds (OHCs) in Arctic char (Salvelinus alpinus) from Bjørnøya, Svalbard (Norway)
Sci Total Environ, 521-522, 421-30
DOI 10.1016/j.scitotenv.2015.03.104, PubMed 25864154
Lack of collagen VIII reduces fibrosis and promotes early mortality and cardiac dilatation in pressure overload in mice
Cardiovasc Res, 106 (1), 32-42
DOI 10.1093/cvr/cvv041, PubMed 25694587
Secretoneurin is a novel prognostic cardiovascular biomarker associated with cardiomyocyte calcium handling
J Am Coll Cardiol, 65 (4), 339-351
DOI 10.1016/j.jacc.2014.10.065, PubMed 25634832
Syndecan-4 is a key determinant of collagen cross-linking and passive myocardial stiffness in the pressure-overloaded heart
Cardiovasc Res, 106 (2), 217-26
DOI 10.1093/cvr/cvv002, PubMed 25587045
Psychological distress and mortality in patients with acute dyspnea: data from the Akershus Cardiac Examination (ACE) 2 Study
Gen Hosp Psychiatry, 37 (6), 548-53
DOI 10.1016/j.genhosppsych.2015.07.007, PubMed 26298205
The homeostatic chemokine CCL21 predicts mortality in aortic stenosis patients and modulates left ventricular remodeling
PLoS One, 9 (11), e112172
DOI 10.1371/journal.pone.0112172, PubMed 25398010
IL-18 neutralization during alveolar hypoxia improves left ventricular diastolic function in mice
Acta Physiol (Oxf), 213 (2), 492-504
DOI 10.1111/apha.12376, PubMed 25182570
Attenuated development of cardiac fibrosis in left ventricular pressure overload by SM16, an orally active inhibitor of ALK5
J Mol Cell Cardiol, 76, 148-57
DOI 10.1016/j.yjmcc.2014.08.008, PubMed 25169971
In active juvenile dermatomyositis, elevated eotaxin and MCP-1 and cholesterol levels in the upper normal range are associated with cardiac dysfunction
Rheumatology (Oxford), 53 (12), 2214-22
DOI 10.1093/rheumatology/keu256, PubMed 24996906
Identifying pathogenic processes by integrating microarray data with prior knowledge
BMC Bioinformatics, 15, 115
DOI 10.1186/1471-2105-15-115, PubMed 24758699
A dominant STIM1 mutation causes Stormorken syndrome
Hum Mutat, 35 (5), 556-64
DOI 10.1002/humu.22544, PubMed 24619930
Increased levels of eotaxin and MCP-1 in juvenile dermatomyositis median 16.8 years after disease onset; associations with disease activity, duration and organ damage
PLoS One, 9 (3), e92171
DOI 10.1371/journal.pone.0092171, PubMed 24647150
Prognostic value of circulating microRNA-210 levels in patients with moderate to severe aortic stenosis
PLoS One, 9 (3), e91812
DOI 10.1371/journal.pone.0091812, PubMed 24626394
Pentosan polysulfate decreases myocardial expression of the extracellular matrix enzyme ADAMTS4 and improves cardiac function in vivo in rats subjected to pressure overload by aortic banding
PLoS One, 9 (3), e89621
DOI 10.1371/journal.pone.0089621, PubMed 24595230
Impaired left ventricular mechanical and energetic function in mice after cardiomyocyte-specific excision of Serca2
Am J Physiol Heart Circ Physiol, 306 (7), H1018-24
DOI 10.1152/ajpheart.00741.2013, PubMed 24486508
Reduced visfatin levels in aortic stenosis increase after aortic valve replacement and may contribute to reverse left ventricular remodelling
J Cardiovasc Surg (Torino), 56 (3), 483-92
PubMed 24429804
The cardiokine secreted Frizzled-related protein 3, a modulator of Wnt signalling, in clinical and experimental heart failure
J Intern Med, 275 (6), 621-30
DOI 10.1111/joim.12175, PubMed 24330105
Prominent heart organ-level performance deficits in a genetic model of targeted severe and progressive SERCA2 deficiency
PLoS One, 8 (11), e79609
DOI 10.1371/journal.pone.0079609, PubMed 24223976
Long-term levosimendan treatment improves systolic function and myocardial relaxation in mice with cardiomyocyte-specific disruption of the Serca2 gene
J Appl Physiol (1985), 115 (10), 1572-80
DOI 10.1152/japplphysiol.01044.2012, PubMed 24072410
SERCA2 activity is involved in the CNP-mediated functional responses in failing rat myocardium
Br J Pharmacol, 170 (2), 366-79
DOI 10.1111/bph.12282, PubMed 23808942
Effect of short- and long-term physical activities on circulating granin protein levels
Regul Pept, 185, 14-9
DOI 10.1016/j.regpep.2013.06.003, PubMed 23816467
Synchrony of cardiomyocyte Ca(2+) release is controlled by T-tubule organization, SR Ca(2+) content, and ryanodine receptor Ca(2+) sensitivity
Biophys J, 104 (8), 1685-97
DOI 10.1016/j.bpj.2013.03.022, PubMed 23601316
The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury
Cardiovasc Res, 99 (1), 164-74
DOI 10.1093/cvr/cvt091, PubMed 23580606
Lumican is increased in experimental and clinical heart failure, and its production by cardiac fibroblasts is induced by mechanical and proinflammatory stimuli
FEBS J, 280 (10), 2382-98
DOI 10.1111/febs.12235, PubMed 23480731
Beta-adrenergic stimulation maintains cardiac function in Serca2 knockout mice
Biophys J, 104 (6), 1349-56
DOI 10.1016/j.bpj.2013.01.042, PubMed 23528094
Innate immune signaling induces expression and shedding of the heparan sulfate proteoglycan syndecan-4 in cardiac fibroblasts and myocytes, affecting inflammation in the pressure-overloaded heart
FEBS J, 280 (10), 2228-47
DOI 10.1111/febs.12161, PubMed 23374111
Lack of pro-inflammatory cytokine mobilization predicts poor prognosis in patients with acute heart failure
Cytokine, 61 (3), 962-9
DOI 10.1016/j.cyto.2013.01.006, PubMed 23415671
Decorin, lumican, and their GAG chain-synthesizing enzymes are regulated in myocardial remodeling and reverse remodeling in the mouse
J Appl Physiol (1985), 114 (8), 988-97
DOI 10.1152/japplphysiol.00793.2012, PubMed 23412898
Differential regulation of extracellular matrix constituents in myocardial remodeling with and without heart failure following pressure overload
Matrix Biol, 32 (2), 133-42
DOI 10.1016/j.matbio.2012.11.011, PubMed 23220517
Syndecan-4 signaling via NFAT regulates extracellular matrix production and cardiac myofibroblast differentiation in response to mechanical stress
J Mol Cell Cardiol, 54, 73-81
DOI 10.1016/j.yjmcc.2012.11.006, PubMed 23178899
IL-18 and IL-12 synergy induces matrix degrading enzymes in the lung
Exp Lung Res, 38 (8), 406-19
DOI 10.3109/01902148.2012.716903, PubMed 22908875
MO-F-BRA-02: Evaluation of 4D CT to 4D Cone-Beam CT Deformable Image Registration for Lung Cancer Adaptive Radiation Therapy
Med Phys, 39 (6Part21), 3875
DOI 10.1118/1.4735821, PubMed 28518270
SU-E-J-192: Static Breath-Hold MRI Based Measurement of Change in Pulmonary Function Following a Course of Radiation Therapy
Med Phys, 39 (6Part9), 3697
DOI 10.1118/1.4735033, PubMed 28519030
SU-E-J-82: Improvement in Reproducibility of Lung Expansion Measures with Respiratory Effort Correction
Med Phys, 39 (6Part7), 3671
DOI 10.1118/1.4734917, PubMed 28519786
SU-D-BRB-05: Small Animal Lung Compliance Imaging: Assessment System for Tissue Sensitivity to Radiation Induced Lung Injury
Med Phys, 39 (6Part3), 3615
DOI 10.1118/1.4734677, PubMed 28517399
Sodium accumulation in SERCA knockout-induced heart failure
Biophys J, 102 (9), 2039-48
DOI 10.1016/j.bpj.2012.03.045, PubMed 22824267
Dephosphorylation of cardiac proteins in vitro - a matter of phosphatase specificity
Proteomics, 12 (7), 973-8
DOI 10.1002/pmic.201100116, PubMed 22522803
Extreme sarcoplasmic reticulum volume loss and compensatory T-tubule remodeling after Serca2 knockout
Proc Natl Acad Sci U S A, 109 (10), 3997-4001
DOI 10.1073/pnas.1120172109, PubMed 22355118
Chemokines regulate small leucine-rich proteoglycans in the extracellular matrix of the pressure-overloaded right ventricle
J Appl Physiol (1985), 112 (8), 1372-82
DOI 10.1152/japplphysiol.01350.2011, PubMed 22345433
The homeostatic chemokine CCL21 predicts mortality and may play a pathogenic role in heart failure
PLoS One, 7 (3), e33038
DOI 10.1371/journal.pone.0033038, PubMed 22427939
Endothelin-1 in the human myocardium and circulating plasma: evaluation before, during and after correction of aortic stenosis with aortic valve replacement
Cardiology, 123 (1), 1-10
DOI 10.1159/000339756, PubMed 22907118
Secretogranin II; a protein increased in the myocardium and circulation in heart failure with cardioprotective properties
PLoS One, 7 (5), e37401
DOI 10.1371/journal.pone.0037401, PubMed 22655045
Cardiac O-GlcNAc signaling is increased in hypertrophy and heart failure
Physiol Genomics, 44 (2), 162-72
DOI 10.1152/physiolgenomics.00016.2011, PubMed 22128088
Inhibition of SMAD2 phosphorylation preserves cardiac function during pressure overload
Cardiovasc Res, 93 (1), 100-10
DOI 10.1093/cvr/cvr294, PubMed 22049534
A mouse model of reverse cardiac remodelling following banding-debanding of the ascending aorta
Acta Physiol (Oxf), 205 (1), 92-102
DOI 10.1111/j.1748-1716.2011.02369.x, PubMed 21974781
Slowed relaxation and preserved maximal force in soleus muscles of mice with targeted disruption of the Serca2 gene in skeletal muscle
J Physiol, 589 (Pt 24), 6139-55
DOI 10.1113/jphysiol.2011.211987, PubMed 21946846
Lack of chemokine signaling through CXCR5 causes increased mortality, ventricular dilatation and deranged matrix during cardiac pressure overload
PLoS One, 6 (4), e18668
DOI 10.1371/journal.pone.0018668, PubMed 21533157
Lack of CCR7 induces pulmonary hypertension involving perivascular leukocyte infiltration and inflammation
Am J Physiol Lung Cell Mol Physiol, 301 (1), L50-9
DOI 10.1152/ajplung.00048.2010, PubMed 21498626
Cortisol response to stress is associated with myocardial remodeling in salmonid fishes
J Exp Biol, 214 (Pt 8), 1313-21
DOI 10.1242/jeb.053058, PubMed 21430209
Angiotensin II and norepinephrine activate specific calcineurin-dependent NFAT transcription factor isoforms in cardiomyocytes
J Appl Physiol (1985), 111 (5), 1278-89
DOI 10.1152/japplphysiol.01383.2010, PubMed 21474694
Calcium dynamics in the ventricular myocytes of SERCA2 knockout mice: A modeling study
Biophys J, 100 (2), 322-31
DOI 10.1016/j.bpj.2010.11.048, PubMed 21244828
Ca(2+) wave probability is determined by the balance between SERCA2-dependent Ca(2+) reuptake and threshold SR Ca(2+) content
Cardiovasc Res, 90 (3), 503-12
DOI 10.1093/cvr/cvr013, PubMed 21242164
Syndecan-4 is essential for development of concentric myocardial hypertrophy via stretch-induced activation of the calcineurin-NFAT pathway
PLoS One, 6 (12), e28302
DOI 10.1371/journal.pone.0028302, PubMed 22164265
Cardiomyocyte-specific disruption of Serca2 in adult mice causes sarco(endo)plasmic reticulum stress and apoptosis
Cell Calcium, 49 (4), 201-7
DOI 10.1016/j.ceca.2010.09.009, PubMed 20965565
Exercise training before cardiac-specific Serca2 disruption attenuates the decline in cardiac function in mice
J Appl Physiol (1985), 109 (6), 1749-55
DOI 10.1152/japplphysiol.00282.2010, PubMed 20864565
Cre-loxP DNA recombination is possible with only minimal unspecific transcriptional changes and without cardiomyopathy in Tg(alphaMHC-MerCreMer) mice
Am J Physiol Heart Circ Physiol, 299 (5), H1671-8
DOI 10.1152/ajpheart.01155.2009, PubMed 20802136
Collagen isoform shift during the early phase of reverse left ventricular remodelling after relief of pressure overload
Eur Heart J, 32 (2), 236-45
DOI 10.1093/eurheartj/ehq166, PubMed 20525982
Chromogranin B in heart failure: a putative cardiac biomarker expressed in the failing myocardium
Circ Heart Fail, 3 (4), 503-11
DOI 10.1161/CIRCHEARTFAILURE.109.867747, PubMed 20519641
Plasma IL-18 and IL-18BP are altered differently in reverse remodeling following aortic valve replacement
Scand Cardiovasc J, 44 (2), 113-8
DOI 10.3109/14017430903426902, PubMed 19961286
Circulating cytokine levels in mice with heart failure are etiology dependent
J Appl Physiol (1985), 108 (5), 1357-64
DOI 10.1152/japplphysiol.01084.2009, PubMed 20224000
High-intensity exercise training in mice with cardiomyocyte-specific disruption of Serca2
J Appl Physiol (1985), 108 (5), 1311-20
DOI 10.1152/japplphysiol.01133.2009, PubMed 20167673
Separate mechanisms cause anemia in ischemic vs. nonischemic murine heart failure
Am J Physiol Regul Integr Comp Physiol, 298 (3), R808-14
DOI 10.1152/ajpregu.00250.2009, PubMed 20032264
Reduced SERCA2 abundance decreases the propensity for Ca2+ wave development in ventricular myocytes
Cardiovasc Res, 86 (1), 63-71
DOI 10.1093/cvr/cvp401, PubMed 20019150
Sodium accumulation promotes diastolic dysfunction in end-stage heart failure following Serca2 knockout
J Physiol, 588 (Pt 3), 465-78
DOI 10.1113/jphysiol.2009.183517, PubMed 20008467
Increased production of CXCL16 in experimental and clinical heart failure: a possible role in extracellular matrix remodeling
Circ Heart Fail, 2 (6), 624-32
DOI 10.1161/CIRCHEARTFAILURE.108.821074, PubMed 19919988
Mice carrying a conditional Serca2(flox) allele for the generation of Ca(2+) handling-deficient mouse models
Cell Calcium, 46 (3), 219-25
DOI 10.1016/j.ceca.2009.07.004, PubMed 19692123
Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure
Eur Heart J, 30 (10), 1229-36
DOI 10.1093/eurheartj/ehp088, PubMed 19329498
Moderate heart dysfunction in mice with inducible cardiomyocyte-specific excision of the Serca2 gene
J Mol Cell Cardiol, 47 (2), 180-7
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In memory of Guro Valen (1960-2014)
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Internprising for bedre økonomisk styring: internprisingspraksis i fire bilfirma sammenlignet med teorien på området
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Atrial natriuretic factor: an experimental study on release mechanisms and on cardiovascular and renal effects
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