Publication list - Publika - Scientific publications from Oslo University Hospital

Publications by Erlend Arnulf Nagelhus

75 publications found

Original articles

Bojarskaite L, Nafari S, Ravnanger AK, Frey MM, Skauli N, Åbjørsbråten KS, Roth LC, Amiry-Moghaddam M, Nagelhus EA, Ottersen OP, Bogen IL, Thoren AE, Enger R (2024)
Role of aquaporin-4 polarization in extracellular solute clearance
Fluids Barriers CNS, 21 (1), 28
DOI 10.1186/s12987-024-00527-7, PubMed 38532513

Hjukse JB, Puebla MFDL, Vindedal GF, Sprengel R, Jensen V, Nagelhus EA, Tang W (2023)
Increased membrane Ca²⁺ permeability drives astrocytic Ca²⁺ dynamics during neuronal stimulation at excitatory synapses
Glia, 71 (12), 2770-2781
DOI 10.1002/glia.24450, PubMed 37564028

Bordoni L, Thoren AE, Gutiérrez-Jiménez E, Åbjørsbråten KS, Bjørnstad DM, Tang W, Stern M, Østergaard L, Nagelhus EA, Frische S, Ottersen OP, Enger R (2023)
Deletion of aquaporin-4 improves capillary blood flow distribution in brain edema
Glia, 71 (11), 2559-2572
DOI 10.1002/glia.24439, PubMed 37439315

Åbjørsbråten KS, Skaaraas GHES, Cunen C, Bjørnstad DM, Binder KMG, Bojarskaite L, Jensen V, Nilsson LNG, Rao SB, Tang W, Hermansen GH, Nagelhus EA, Ottersen OP, Torp R, Enger R (2022)
Impaired astrocytic Ca²⁺ signaling in awake-behaving Alzheimer's disease transgenic mice
Elife, 11
DOI 10.7554/eLife.75055, PubMed 35833623

Henneberger C, Bard L, Panatier A, Reynolds JP, Kopach O, Medvedev NI, Minge D, Herde MK, Anders S, Kraev I, Heller JP, Rama S, Zheng K, Jensen TP, Sanchez-Romero I, Jackson CJ, Janovjak H, Ottersen OP, Nagelhus EA, Oliet SHR, Stewart MG, Nägerl UV, Rusakov DA (2020)
LTP Induction Boosts Glutamate Spillover by Driving Withdrawal of Perisynaptic Astroglia
Neuron, 108 (5), 919-936.e11
DOI 10.1016/j.neuron.2020.08.030, PubMed 32976770

Harrison IF, Ismail O, Machhada A, Colgan N, Ohene Y, Nahavandi P, Ahmed Z, Fisher A, Meftah S, Murray TK, Ottersen OP, Nagelhus EA, O'Neill MJ, Wells JA, Lythgoe MF (2020)
Impaired glymphatic function and clearance of tau in an Alzheimer's disease model
Brain, 143 (8), 2576-2593
DOI 10.1093/brain/awaa179, PubMed 32705145

Bojarskaite L, Bjørnstad DM, Pettersen KH, Cunen C, Hermansen GH, Åbjørsbråten KS, Chambers AR, Sprengel R, Vervaeke K, Tang W, Enger R, Nagelhus EA (2020)
Astrocytic Ca²⁺ signaling is reduced during sleep and is involved in the regulation of slow wave sleep
Nat Commun, 11 (1), 3240
DOI 10.1038/s41467-020-17062-2, PubMed 32632168

Caglayan S, Hashim A, Cieslar-Pobuda A, Jensen V, Behringer S, Talug B, Chu DT, Pecquet C, Rogne M, Brech A, Brorson SH, Nagelhus EA, Hannibal L, Boschi A, Taskén K, Staerk J (2020)
Optic Atrophy 1 Controls Human Neuronal Development by Preventing Aberrant Nuclear DNA Methylation
iScience, 23 (6), 101154
DOI 10.1016/j.isci.2020.101154, PubMed 32450518

Hasan-Olive MM, Enger R, Hansson HA, Nagelhus EA, Eide PK (2019)
Pathological mitochondria in neurons and perivascular astrocytic endfeet of idiopathic normal pressure hydrocephalus patients
Fluids Barriers CNS, 16 (1), 39
DOI 10.1186/s12987-019-0160-7, PubMed 31849332

Hasan-Olive MM, Hansson HA, Enger R, Nagelhus EA, Eide PK (2019)
Blood-Brain Barrier Dysfunction in Idiopathic Intracranial Hypertension
J Neuropathol Exp Neurol, 78 (9), 808-818
DOI 10.1093/jnen/nlz063, PubMed 31393574

Eilert-Olsen M, Hjukse JB, Thoren AE, Tang W, Enger R, Jensen V, Pettersen KH, Nagelhus EA (2019)
Astroglial endfeet exhibit distinct Ca²⁺ signals during hypoosmotic conditions
Glia, 67 (12), 2399-2409
DOI 10.1002/glia.23692, PubMed 31350866

Rosic B, Dukefoss DB, Åbjørsbråten KS, Tang W, Jensen V, Ottersen OP, Enger R, Nagelhus EA (2019)
Aquaporin-4-independent volume dynamics of astroglial endfeet during cortical spreading depression
Glia, 67 (6), 1113-1121
DOI 10.1002/glia.23604, PubMed 30791140

Ohene Y, Harrison IF, Nahavandi P, Ismail O, Bird EV, Ottersen OP, Nagelhus EA, Thomas DL, Lythgoe MF, Wells JA (2018)
Non-invasive MRI of brain clearance pathways using multiple echo time arterial spin labelling: an aquaporin-4 study
Neuroimage, 188, 515-523
DOI 10.1016/j.neuroimage.2018.12.026, PubMed 30557661

Aryal S, Hussain S, Drevon CA, Nagelhus E, Hvalby Ø, Jensen V, Walaas SI, Davanger S (2018)
Omega-3 fatty acids regulate plasticity in distinct hippocampal glutamatergic synapses
Eur J Neurosci, 49 (1), 40-50
DOI 10.1111/ejn.14224, PubMed 30367533

Heuser K, Nome CG, Pettersen KH, Åbjørsbråten KS, Jensen V, Tang W, Sprengel R, Taubøll E, Nagelhus EA, Enger R (2018)
Ca2+ Signals in Astrocytes Facilitate Spread of Epileptiform Activity
Cereb Cortex, 28 (11), 4036-4048
DOI 10.1093/cercor/bhy196, PubMed 30169757

Hasan-Olive MM, Enger R, Hansson HA, Nagelhus EA, Eide PK (2018)
Loss of perivascular aquaporin-4 in idiopathic normal pressure hydrocephalus
Glia, 67 (1), 91-100
DOI 10.1002/glia.23528, PubMed 30306658

Eidsvaag VA, Hansson HA, Heuser K, Nagelhus EA, Eide PK (2018)
Cerebral microvascular abnormalities in patients with idiopathic intracranial hypertension
Brain Res, 1686, 72-82
DOI 10.1016/j.brainres.2018.02.017, PubMed 29477544

Eidsvaag VA, Hansson HA, Heuser K, Nagelhus EA, Eide PK (2017)
Brain Capillary Ultrastructure in Idiopathic Normal Pressure Hydrocephalus: Relationship With Static and Pulsatile Intracranial Pressure
J Neuropathol Exp Neurol, 76 (12), 1034-1045
DOI 10.1093/jnen/nlx091, PubMed 29040647

Holter KE, Kehlet B, Devor A, Sejnowski TJ, Dale AM, Omholt SW, Ottersen OP, Nagelhus EA, Mardal KA, Pettersen KH (2017)
Interstitial solute transport in 3D reconstructed neuropil occurs by diffusion rather than bulk flow
Proc Natl Acad Sci U S A, 114 (37), 9894-9899
DOI 10.1073/pnas.1706942114, PubMed 28847942

Eidsvaag VA, Enger R, Hansson HA, Eide PK, Nagelhus EA (2017)
Human and mouse cortical astrocytes differ in aquaporin-4 polarization toward microvessels
Glia, 65 (6), 964-973
DOI 10.1002/glia.23138, PubMed 28317216

Enger R, Dukefoss DB, Tang W, Pettersen KH, Bjørnstad DM, Helm PJ, Jensen V, Sprengel R, Vervaeke K, Ottersen OP, Nagelhus EA (2017)
Deletion of Aquaporin-4 Curtails Extracellular Glutamate Elevation in Cortical Spreading Depression in Awake Mice
Cereb Cortex, 27 (1), 24-33
DOI 10.1093/cercor/bhw359, PubMed 28365776

Pavlin T, Nagelhus EA, Brekken C, Eyjolfsson EM, Thoren A, Haraldseth O, Sonnewald U, Ottersen OP, Håberg AK (2016)
Loss or Mislocalization of Aquaporin-4 Affects Diffusion Properties and Intermediary Metabolism in Gray Matter of Mice
Neurochem Res, 42 (1), 77-91
DOI 10.1007/s11064-016-2139-y, PubMed 28039592

Vindedal GF, Thoren AE, Jensen V, Klungland A, Zhang Y, Holtzman MJ, Ottersen OP, Nagelhus EA (2016)
Removal of aquaporin-4 from glial and ependymal membranes causes brain water accumulation
Mol Cell Neurosci, 77, 47-52
DOI 10.1016/j.mcn.2016.10.004, PubMed 27751903

Eide PK, Eidsvaag VA, Nagelhus EA, Hansson HA (2016)
Cortical astrogliosis and increased perivascular aquaporin-4 in idiopathic intracranial hypertension
Brain Res, 1644, 161-75
DOI 10.1016/j.brainres.2016.05.024, PubMed 27188961

Enger R, Tang W, Vindedal GF, Jensen V, Johannes Helm P, Sprengel R, Looger LL, Nagelhus EA (2015)
Dynamics of Ionic Shifts in Cortical Spreading Depression
Cereb Cortex, 25 (11), 4469-76
DOI 10.1093/cercor/bhv054, PubMed 25840424

Szokol K, Heuser K, Tang W, Jensen V, Enger R, Bedner P, Steinhäuser C, Taubøll E, Ottersen OP, Nagelhus EA (2015)
Augmentation of Ca(2+) signaling in astrocytic endfeet in the latent phase of temporal lobe epilepsy
Front Cell Neurosci, 9, 49
DOI 10.3389/fncel.2015.00049, PubMed 25762896

Tang W, Szokol K, Jensen V, Enger R, Trivedi CA, Hvalby Ø, Helm PJ, Looger LL, Sprengel R, Nagelhus EA (2015)
Stimulation-evoked Ca2+ signals in astrocytic processes at hippocampal CA3-CA1 synapses of adult mice are modulated by glutamate and ATP
J Neurosci, 35 (7), 3016-21
DOI 10.1523/JNEUROSCI.3319-14.2015, PubMed 25698739

Haj-Yasein NN, Bugge CE, Jensen V, Østby I, Ottersen OP, Hvalby Ø, Nagelhus EA (2014)
Deletion of aquaporin-4 increases extracellular K(+) concentration during synaptic stimulation in mouse hippocampus
Brain Struct Funct, 220 (4), 2469-74
DOI 10.1007/s00429-014-0767-z, PubMed 24744149

Rangroo Thrane V, Thrane AS, Wang F, Cotrina ML, Smith NA, Chen M, Xu Q, Kang N, Fujita T, Nagelhus EA, Nedergaard M (2013)
Ammonia triggers neuronal disinhibition and seizures by impairing astrocyte potassium buffering
Nat Med, 19 (12), 1643-8
DOI 10.1038/nm.3400, PubMed 24240184

Nagelhus EA, Amiry-Moghaddam M, Bergersen LH, Bjaalie JG, Eriksson J, Gundersen V, Leergaard TB, Morth JP, Storm-Mathisen J, Torp R, Walhovd KB, Tønjum T (2013)
The glia doctrine: addressing the role of glial cells in healthy brain ageing
Mech Ageing Dev, 134 (10), 449-59
DOI 10.1016/j.mad.2013.10.001, PubMed 24141107

Gundersen GA, Vindedal GF, Skare O, Nagelhus EA (2013)
Evidence that pericytes regulate aquaporin-4 polarization in mouse cortical astrocytes
Brain Struct Funct, 219 (6), 2181-6
DOI 10.1007/s00429-013-0629-0, PubMed 23982198

Thrane AS, Takano T, Rangroo Thrane V, Wang F, Peng W, Ottersen OP, Nedergaard M, Nagelhus EA (2013)
In vivo NADH fluorescence imaging indicates effect of aquaporin-4 deletion on oxygen microdistribution in cortical spreading depression
J Cereb Blood Flow Metab, 33 (7), 996-9
DOI 10.1038/jcbfm.2013.63, PubMed 23611872

Rangroo Thrane V, Thrane AS, Plog BA, Thiyagarajan M, Iliff JJ, Deane R, Nagelhus EA, Nedergaard M (2013)
Paravascular microcirculation facilitates rapid lipid transport and astrocyte signaling in the brain
Sci Rep, 3, 2582
DOI 10.1038/srep02582, PubMed 24002448

Thrane AS, Rangroo Thrane V, Zeppenfeld D, Lou N, Xu Q, Nagelhus EA, Nedergaard M (2012)
General anesthesia selectively disrupts astrocyte calcium signaling in the awake mouse cortex
Proc Natl Acad Sci U S A, 109 (46), 18974-9
DOI 10.1073/pnas.1209448109, PubMed 23112168

Enger R, Gundersen GA, Haj-Yasein NN, Eilert-Olsen M, Thoren AE, Vindedal GF, Petersen PH, Skare Ø, Nedergaard M, Ottersen OP, Nagelhus EA (2012)
Molecular scaffolds underpinning macroglial polarization: an analysis of retinal Müller cells and brain astrocytes in mouse
Glia, 60 (12), 2018-26
DOI 10.1002/glia.22416, PubMed 22987438

Heuser K, Eid T, Lauritzen F, Thoren AE, Vindedal GF, Taubøll E, Gjerstad L, Spencer DD, Ottersen OP, Nagelhus EA, de Lanerolle NC (2012)
Loss of perivascular Kir4.1 potassium channels in the sclerotic hippocampus of patients with mesial temporal lobe epilepsy
J Neuropathol Exp Neurol, 71 (9), 814-25
DOI 10.1097/NEN.0b013e318267b5af, PubMed 22878665

Iliff JJ, Wang M, Liao Y, Plogg BA, Peng W, Gundersen GA, Benveniste H, Vates GE, Deane R, Goldman SA, Nagelhus EA, Nedergaard M (2012)
A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β
Sci Transl Med, 4 (147), 147ra111
DOI 10.1126/scitranslmed.3003748, PubMed 22896675

Rangroo Thrane V, Thrane AS, Chang J, Alleluia V, Nagelhus EA, Nedergaard M (2012)
Real-time analysis of microglial activation and motility in hepatic and hyperammonemic encephalopathy
Neuroscience, 220, 247-55
DOI 10.1016/j.neuroscience.2012.06.022, PubMed 22728097

Haj-Yasein NN, Jensen V, Østby I, Omholt SW, Voipio J, Kaila K, Ottersen OP, Hvalby Ø, Nagelhus EA (2012)
Aquaporin-4 regulates extracellular space volume dynamics during high-frequency synaptic stimulation: a gene deletion study in mouse hippocampus
Glia, 60 (6), 867-74
DOI 10.1002/glia.22319, PubMed 22419561

Eilert-Olsen M, Haj-Yasein NN, Vindedal GF, Enger R, Gundersen GA, Hoddevik EH, Petersen PH, Haug FM, Skare Ø, Adams ME, Froehner SC, Burkhardt JM, Thoren AE, Nagelhus EA (2011)
Deletion of aquaporin-4 changes the perivascular glial protein scaffold without disrupting the brain endothelial barrier
Glia, 60 (3), 432-40
DOI 10.1002/glia.22277, PubMed 22131281

Haj-Yasein NN, Vindedal GF, Eilert-Olsen M, Gundersen GA, Skare Ø, Laake P, Klungland A, Thorén AE, Burkhardt JM, Ottersen OP, Nagelhus EA (2011)
Glial-conditional deletion of aquaporin-4 (Aqp4) reduces blood-brain water uptake and confers barrier function on perivascular astrocyte endfeet
Proc Natl Acad Sci U S A, 108 (43), 17815-20
DOI 10.1073/pnas.1110655108, PubMed 21990350

Kerty E, Heuser K, Indahl UG, Berg PR, Nakken S, Lien S, Omholt SW, Ottersen OP, Nagelhus EA (2011)
Is the brain water channel aquaporin-4 a pathogenetic factor in idiopathic intracranial hypertension? Results from a combined clinical and genetic study in a Norwegian cohort
Acta Ophthalmol, 91 (1), 88-91
DOI 10.1111/j.1755-3768.2011.02231.x, PubMed 21914143

Haj-Yasein NN, Jensen V, Vindedal GF, Gundersen GA, Klungland A, Ottersen OP, Hvalby O, Nagelhus EA (2011)
Evidence that compromised K+ spatial buffering contributes to the epileptogenic effect of mutations in the human Kir4.1 gene (KCNJ10)
Glia, 59 (11), 1635-42
DOI 10.1002/glia.21205, PubMed 21748805

Thrane AS, Rappold PM, Fujita T, Torres A, Bekar LK, Takano T, Peng W, Wang F, Rangroo Thrane V, Enger R, Haj-Yasein NN, Skare Ø, Holen T, Klungland A, Ottersen OP, Nedergaard M, Nagelhus EA (2010)
Critical role of aquaporin-4 (AQP4) in astrocytic Ca2+ signaling events elicited by cerebral edema
Proc Natl Acad Sci U S A, 108 (2), 846-51
DOI 10.1073/pnas.1015217108, PubMed 21187412

Heuser K, Hoddevik EH, Taubøll E, Gjerstad L, Indahl U, Kaczmarek L, Berg PR, Lien S, Nagelhus EA, Ottersen OP (2010)
Temporal lobe epilepsy and matrix metalloproteinase 9: a tempting relation but negative genetic association
Seizure, 19 (6), 335-8
DOI 10.1016/j.seizure.2010.05.003, PubMed 20605480

Heuser K, Nagelhus EA, Taubøll E, Indahl U, Berg PR, Lien S, Nakken S, Gjerstad L, Ottersen OP (2009)
Variants of the genes encoding AQP4 and Kir4.1 are associated with subgroups of patients with temporal lobe epilepsy
Epilepsy Res, 88 (1), 55-64
DOI 10.1016/j.eplepsyres.2009.09.023, PubMed 19864112

Østby I, Øyehaug L, Einevoll GT, Nagelhus EA, Plahte E, Zeuthen T, Lloyd CM, Ottersen OP, Omholt SW (2009)
Astrocytic mechanisms explaining neural-activity-induced shrinkage of extraneuronal space
PLoS Comput Biol, 5 (1), e1000272
DOI 10.1371/journal.pcbi.1000272, PubMed 19165313

Heuser K, Taubøll E, Nagelhus EA, Cvancarova M, Petter Ottersen O, Gjerstad L (2009)
Phenotypic characteristics of temporal lobe epilepsy: the impact of hippocampal sclerosis
Acta Neurol Scand Suppl (189), 8-13
DOI 10.1111/j.1600-0404.2009.01205.x, PubMed 19566491

Puwarawuttipanit W, Bragg AD, Frydenlund DS, Mylonakou MN, Nagelhus EA, Peters MF, Kotchabhakdi N, Adams ME, Froehner SC, Haug FM, Ottersen OP, Amiry-Moghaddam M (2005)
Differential effect of alpha-syntrophin knockout on aquaporin-4 and Kir4.1 expression in retinal macroglial cells in mice
Neuroscience, 137 (1), 165-75
DOI 10.1016/j.neuroscience.2005.08.051, PubMed 16257493

Nagelhus EA, Mathiisen TM, Bateman AC, Haug FM, Ottersen OP, Grubb JH, Waheed A, Sly WS (2005)
Carbonic anhydrase XIV is enriched in specific membrane domains of retinal pigment epithelium, Muller cells, and astrocytes
Proc Natl Acad Sci U S A, 102 (22), 8030-5
DOI 10.1073/pnas.0503021102, PubMed 15901897

Nagelhus EA, Mathiisen TM, Ottersen OP (2004)
Aquaporin-4 in the central nervous system: cellular and subcellular distribution and coexpression with KIR4.1
Neuroscience, 129 (4), 905-13
DOI 10.1016/j.neuroscience.2004.08.053, PubMed 15561407

Amiry-Moghaddam M, Williamson A, Palomba M, Eid T, de Lanerolle NC, Nagelhus EA, Adams ME, Froehner SC, Agre P, Ottersen OP (2003)
Delayed K+ clearance associated with aquaporin-4 mislocalization: phenotypic defects in brains of alpha-syntrophin-null mice
Proc Natl Acad Sci U S A, 100 (23), 13615-20
DOI 10.1073/pnas.2336064100, PubMed 14597704

Fujita A, Horio Y, Nielsen S, Nagelhus EA, Hata F, Ottersen OP, Kurachi Y (1999)
High-resolution immunogold cytochemistry indicates that AQP4 is concentrated along the basal membrane of parietal cell in rat stomach
FEBS Lett, 459 (3), 305-9
DOI 10.1016/s0014-5793(99)01256-9, PubMed 10526154

Bergersen L, Jóhannsson E, Veruki ML, Nagelhus EA, Halestrap A, Sejersted OM, Ottersen OP (1999)
Cellular and subcellular expression of monocarboxylate transporters in the pigment epithelium and retina of the rat
Neuroscience, 90 (1), 319-31
DOI 10.1016/s0306-4522(98)00427-8, PubMed 10188957

Wen H, Nagelhus EA, Amiry-Moghaddam M, Agre P, Ottersen OP, Nielsen S (1999)
Ontogeny of water transport in rat brain: postnatal expression of the aquaporin-4 water channel
Eur J Neurosci, 11 (3), 935-45
DOI 10.1046/j.1460-9568.1999.00502.x, PubMed 10103087

Nagelhus EA, Horio Y, Inanobe A, Fujita A, Haug FM, Nielsen S, Kurachi Y, Ottersen OP (1999)
Immunogold evidence suggests that coupling of K+ siphoning and water transport in rat retinal Müller cells is mediated by a coenrichment of Kir4.1 and AQP4 in specific membrane domains
Glia, 26 (1), 47-54
DOI 10.1002/(sici)1098-1136(199903)26:1<47::aid-glia5>3.0.co;2-5, PubMed 10088671

Takumi Y, Nagelhus EA, Eidet J, Matsubara A, Usami S, Shinkawa H, Nielsen S, Ottersen OP (1998)
Select types of supporting cell in the inner ear express aquaporin-4 water channel protein
Eur J Neurosci, 10 (12), 3584-95
DOI 10.1046/j.1460-9568.1998.00360.x, PubMed 9875338

Huster D, Hjelle OP, Haug FM, Nagelhus EA, Reichelt W, Ottersen OP (1998)
Subcellular compartmentation of glutathione and glutathione precursors. A high resolution immunogold analysis of the outer retina of guinea pig
Anat Embryol (Berl), 198 (4), 277-87
DOI 10.1007/s004290050184, PubMed 9764542

Hamann S, Zeuthen T, La Cour M, Nagelhus EA, Ottersen OP, Agre P, Nielsen S (1998)
Aquaporins in complex tissues: distribution of aquaporins 1-5 in human and rat eye
Am J Physiol, 274 (5), C1332-45
DOI 10.1152/ajpcell.1998.274.5.C1332, PubMed 9612221

Jóhannsson E, Nagelhus EA, McCullagh KJ, Sejersted OM, Blackstad TW, Bonen A, Ottersen OP (1997)
Cellular and subcellular expression of the monocarboxylate transporter MCT1 in rat heart. A high-resolution immunogold analysis
Circ Res, 80 (3), 400-7
DOI 10.1161/01.res.0000435856.47954.71, PubMed 9048661

Nielsen S, Nagelhus EA, Amiry-Moghaddam M, Bourque C, Agre P, Ottersen OP (1997)
Specialized membrane domains for water transport in glial cells: high-resolution immunogold cytochemistry of aquaporin-4 in rat brain
J Neurosci, 17 (1), 171-80
DOI 10.1523/JNEUROSCI.17-01-00171.1997, PubMed 8987746

Nagelhus EA, Lehmann A, Ottersen OP (1996)
Neuronal and glial handling of glutamate and glutamine during hypoosmotic stress: a biochemical and quantitative immunocytochemical analysis using the rat cerebellum as a model
Neuroscience, 72 (3), 743-55
DOI 10.1016/0306-4522(96)00003-6, PubMed 9157320

Amiry-Moghaddam M, Nagelhus EA, Agre P, Nielsen S, Ottersen OP (1996)
Taurine and water channels are co-localized in renal tubule cells and other tissues. Immunocytochemical studies in rats
Adv Exp Med Biol, 403, 165-71
DOI 10.1007/978-1-4899-0182-8_19, PubMed 8915354

Nagelhus EA, Amiry-Moghaddam M, Lehmann A, Ottersen OP (1994)
Taurine as an organic osmolyte in the intact brain: immunocytochemical and biochemical studies
Adv Exp Med Biol, 359, 325-34
DOI 10.1007/978-1-4899-1471-2_33, PubMed 7887272

Amiry-Moghaddam M, Nagelhus E, Ottersen OP (1994)
Light- and electronmicroscopic distribution of taurine, an organic osmolyte, in rat renal tubule cells
Kidney Int, 45 (1), 10-22
DOI 10.1038/ki.1994.2, PubMed 8126997

Nagelhus EA, Lehmann A, Ottersen OP (1993)
Neuronal-glial exchange of taurine during hypo-osmotic stress: a combined immunocytochemical and biochemical analysis in rat cerebellar cortex
Neuroscience, 54 (3), 615-31
DOI 10.1016/0306-4522(93)90233-6, PubMed 8332252

Lehmann A, Carlström C, Nagelhus EA, Ottersen OP (1991)
Elevation of taurine in hippocampal extracellular fluid and cerebrospinal fluid of acutely hypoosmotic rats: contribution by influx from blood?
J Neurochem, 56 (2), 690-7
DOI 10.1111/j.1471-4159.1991.tb08204.x, PubMed 1899110

Zhang NH, Laake J, Nagelhus E, Storm-Mathisen J, Ottersen OP (1991)
Distribution of glutamine-like immunoreactivity in the cerebellum of rat and baboon (Papio anubis) with reference to the issue of metabolic compartmentation
Anat Embryol (Berl), 184 (3), 213-23
DOI 10.1007/BF01673257, PubMed 1686533

Review articles

Nagelhus EA, Ottersen OP (2013)
Physiological roles of aquaporin-4 in brain
Physiol Rev, 93 (4), 1543-62
DOI 10.1152/physrev.00011.2013, PubMed 24137016

Binder DK, Nagelhus EA, Ottersen OP (2012)
Aquaporin-4 and epilepsy
Glia, 60 (8), 1203-14
DOI 10.1002/glia.22317, PubMed 22378467

Nagelhus EA, Veruki ML, Torp R, Haug FM, Laake JH, Nielsen S, Agre P, Ottersen OP (1998)
Aquaporin-4 water channel protein in the rat retina and optic nerve: polarized expression in Müller cells and fibrous astrocytes
J Neurosci, 18 (7), 2506-19
DOI 10.1523/JNEUROSCI.18-07-02506.1998, PubMed 9502811

Ottersen OP, Chaudhry FA, Danbolt NC, Laake JH, Nagelhus EA, Storm-Mathisen J, Torp R (1997)
Molecular organization of cerebellar glutamate synapses
Prog Brain Res, 114, 97-107
DOI 10.1016/s0079-6123(08)63360-9, PubMed 9193140