Publication list - Publika - Scientific publications from Oslo University Hospital

Publications by Jarle Vaage

56 publications found

Original articles

Chaban V, de Boer E, McAdam KE, Vaage J, Mollnes TE, Nilsson PH, Pischke SE, Islam R (2023)
Escherichia coli-induced inflammatory responses are temperature-dependent in human whole blood ex vivo
Mol Immunol, 157, 70-77
DOI 10.1016/j.molimm.2023.03.006, PubMed 37001293

Baysa A, Maghazachi AA, Sand KL, Campesan M, Zaglia T, Mongillo M, Giorgio M, Di Lisa F, Gullestad L, Mariero LH, Vaage J, Valen G, Stensløkken KO (2022)
Toll-like receptor 9 signaling after myocardial infarction: Role of p66ShcA adaptor protein
Biochem Biophys Res Commun, 644, 70-78
DOI 10.1016/j.bbrc.2022.12.085, PubMed 36634584

Semenova D, Zabirnyk A, Lobov A, Boyarskaya N, Kachanova O, Uspensky V, Zainullina B, Denisov E, Gerashchenko T, Kvitting JP, Kaljusto ML, Thiede B, Kostareva A, Stensløkken KO, Vaage J, Malashicheva A (2022)
Multi-omics of in vitro aortic valve calcification
Front Cardiovasc Med, 9, 1043165
DOI 10.3389/fcvm.2022.1043165, PubMed 36407442

de Boer E, Sokolova M, Quach HQ, McAdam KE, Götz MP, Chaban V, Vaage J, Fageräng B, Woodruff TM, Garred P, Nilsson PH, Mollnes TE, Pischke SE (2022)
Synthetic Oligodeoxynucleotide CpG Motifs Activate Human Complement through Their Backbone Structure and Induce Complement-Dependent Cytokine Release
J Immunol, 209 (9), 1760-1767
DOI 10.4049/jimmunol.2101191, PubMed 36104112

Kaljusto ML, Bautin A, Jakobsen Ø, Wilimski R, Brunborg C, Wennemo M, Karpova L, Nergaard Aas K, Arendarczyk A, Landsverk SA, Galagudza M, Næsheim T, Czub P, Gordeev M, Vaage J (2022)
Effects of ischaemic postconditioning in aortic valve replacement: a multicenter randomized controlled trial
Eur J Cardiothorac Surg, 61 (5), 1144-1152
DOI 10.1093/ejcts/ezab500, PubMed 34849659

Torp MK, Ranheim T, Schjalm C, Hjorth M, Heiestad CM, Dalen KT, Nilsson PH, Mollnes TE, Pischke SE, Lien E, Vaage J, Yndestad A, Stensløkken KO (2022)
Intracellular Complement Component 3 Attenuated Ischemia-Reperfusion Injury in the Isolated Buffer-Perfused Mouse Heart and Is Associated With Improved Metabolic Homeostasis
Front Immunol, 13, 870811
DOI 10.3389/fimmu.2022.870811, PubMed 35432387

Chaban V, Nakstad ER, Stær-Jensen H, Schjalm C, Seljeflot I, Vaage J, Lundqvist C, Benth JŠ, Sunde K, Mollnes TE, Andersen GØ, Pischke SE (2021)
Complement activation is associated with poor outcome after out-of-hospital cardiac arrest
Resuscitation, 166, 129-136
DOI 10.1016/j.resuscitation.2021.05.038, PubMed 34126135

Li Y, Khanal P, Norheim F, Hjorth M, Bjellaas T, Drevon CA, Vaage J, Kimmel AR, Dalen KT (2021)
Plin2 deletion increases cholesteryl ester lipid droplet content and disturbs cholesterol balance in adrenal cortex
J Lipid Res, 62, 100048
DOI 10.1016/j.jlr.2021.100048, PubMed 33582145

Li Y, Torp MK, Norheim F, Khanal P, Kimmel AR, Stensløkken KO, Vaage J, Dalen KT (2020)
Isolated Plin5-deficient cardiomyocytes store less lipid droplets than normal, but without increased sensitivity to hypoxia
Biochim Biophys Acta Mol Cell Biol Lipids, 1866 (4), 158873
DOI 10.1016/j.bbalip.2020.158873, PubMed 33373698

Zabirnyk A, Perez MDM, Blasco M, Stensløkken KO, Ferrer MD, Salcedo C, Vaage J (2020)
A Novel Ex Vivo Model of Aortic Valve Calcification. A Preliminary Report
Front Pharmacol, 11, 568764
DOI 10.3389/fphar.2020.568764, PubMed 33390945

Mariero LH, Torp MK, Heiestad CM, Baysa A, Li Y, Valen G, Vaage J, Stensløkken KO (2019)
Inhibiting nucleolin reduces inflammation induced by mitochondrial DNA in cardiomyocytes exposed to hypoxia and reoxygenation
Br J Pharmacol, 176 (22), 4360-4372
DOI 10.1111/bph.14830, PubMed 31412132

Bogdanova M, Zabirnyk A, Malashicheva A, Enayati KZ, Karlsen TA, Kaljusto ML, Kvitting JP, Dissen E, Sullivan GJ, Kostareva A, Stensløkken KO, Rutkovskiy A, Vaage J (2019)
Interstitial cells in calcified aortic valves have reduced differentiation potential and stem cell-like properties
Sci Rep, 9 (1), 12934
DOI 10.1038/s41598-019-49016-0, PubMed 31506459

Rutkovskiy A, Lund M, Siamansour TS, Reine TM, Kolset SO, Sand KL, Ignatieva E, Gordeev ML, Stensløkken KO, Valen G, Vaage J, Malashicheva A (2019)
Mechanical stress alters the expression of calcification-related genes in vascular interstitial and endothelial cells
Interact Cardiovasc Thorac Surg, 28 (5), 803-811
DOI 10.1093/icvts/ivy339, PubMed 30602018

Zabirnyk A, Ferrer MD, Bogdanova M, Pérez MM, Salcedo C, Kaljusto ML, Kvitting JP, Stensløkken KO, Perelló J, Vaage J (2019)
SNF472, a novel anti-crystallization agent, inhibits induced calcification in an in vitro model of human aortic valve calcification
Vascul Pharmacol, 122-123, 106583
DOI 10.1016/j.vph.2019.106583, PubMed 31437530

Baysa A, Fedorov A, Kondratov K, Ruusalepp A, Minasian S, Galagudza M, Popov M, Kurapeev D, Yakovlev A, Valen G, Kostareva A, Vaage J, Stensløkken KO (2018)
Release of Mitochondrial and Nuclear DNA During On-Pump Heart Surgery: Kinetics and Relation to Extracellular Vesicles
J Cardiovasc Transl Res, 12 (3), 184-192
DOI 10.1007/s12265-018-9848-3, PubMed 30542983

Bogdanova M, Kostina A, Zihlavnikova Enayati K, Zabirnyk A, Malashicheva A, Stensløkken KO, Sullivan GJ, Kaljusto ML, Kvitting JP, Kostareva A, Vaage J, Rutkovskiy A (2018)
Inflammation and Mechanical Stress Stimulate Osteogenic Differentiation of Human Aortic Valve Interstitial Cells
Front Physiol, 9, 1635
DOI 10.3389/fphys.2018.01635, PubMed 30524301

Kimose HH, Randsbæk F, Christensen TD, Valen G, Bøtker HE, Vaage J (2018)
A dose-response study of glutamate supplementation in isolated, perfused rat hearts undergoing ischaemia and cold cardioplegia
Eur J Cardiothorac Surg, 53 (3), 664-671
DOI 10.1093/ejcts/ezx368, PubMed 29069350

Kostina A, Shishkova A, Ignatieva E, Irtyuga O, Bogdanova M, Levchuk K, Golovkin A, Zhiduleva E, Uspenskiy V, Moiseeva O, Faggian G, Vaage J, Kostareva A, Rutkovskiy A, Malashicheva A (2017)
Different Notch signaling in cells from calcified bicuspid and tricuspid aortic valves
J Mol Cell Cardiol, 114, 211-219
DOI 10.1016/j.yjmcc.2017.11.009, PubMed 29158034

Rutkovskiy A, Sagave J, Czibik G, Baysa A, Zihlavnikova Enayati K, Hillestad V, Dahl CP, Fiane A, Gullestad L, Gravning J, Ahmed S, Attramadal H, Valen G, Vaage J (2017)
Connective tissue growth factor and bone morphogenetic protein 2 are induced following myocardial ischemia in mice and humans
Scand J Clin Lab Invest, 77 (5), 321-331
DOI 10.1080/00365513.2017.1318447, PubMed 28460577

Sonin D, Papayan G, Pochkaeva E, Chefu S, Minasian S, Kurapeev D, Vaage J, Petrishchev N, Galagudza M (2016)
In vivo visualization and ex vivo quantification of experimental myocardial infarction by indocyanine green fluorescence imaging
Biomed Opt Express, 8 (1), 151-161
DOI 10.1364/BOE.8.000151, PubMed 28101408

Bliksøen M, Rutkovskiy A, Vaage J, Stensløkken KO (2016)
Mode of perfusion influences infarct size, coronary flow and stress kinases in the isolated mouse heart
Acta Physiol (Oxf), 220 (1), 36-46
DOI 10.1111/apha.12773, PubMed 27543941

Bliksøen M, Mariero LH, Torp MK, Baysa A, Ytrehus K, Haugen F, Seljeflot I, Vaage J, Valen G, Stensløkken KO (2016)
Extracellular mtDNA activates NF-κB via toll-like receptor 9 and induces cell death in cardiomyocytes
Basic Res Cardiol, 111 (4), 42
DOI 10.1007/s00395-016-0553-6, PubMed 27164906

Malashicheva A, Kostina D, Kostina A, Irtyuga O, Voronkina I, Smagina L, Ignatieva E, Gavriliuk N, Uspensky V, Moiseeva O, Vaage J, Kostareva A (2016)
Phenotypic and Functional Changes of Endothelial and Smooth Muscle Cells in Thoracic Aortic Aneurysms
Int J Vasc Med, 2016, 3107879
DOI 10.1155/2016/3107879, PubMed 26904289

Reine TM, Vuong TT, Rutkovskiy A, Meen AJ, Vaage J, Jenssen TG, Kolset SO (2015)
Serglycin in Quiescent and Proliferating Primary Endothelial Cells
PLoS One, 10 (12), e0145584
DOI 10.1371/journal.pone.0145584, PubMed 26694746

Risøe PK, Rutkovskiy A, Ågren J, Kolseth IB, Kjeldsen SF, Valen G, Vaage J, Dahle MK (2015)
Higher TNFα responses in young males compared to females are associated with attenuation of monocyte adenylyl cyclase expression
Hum Immunol, 76 (6), 427-30
DOI 10.1016/j.humimm.2015.03.018, PubMed 25959651

Bliksøen M, Baysa A, Eide L, Bjørås M, Suganthan R, Vaage J, Stensløkken KO, Valen G (2014)
Mitochondrial DNA damage and repair during ischemia-reperfusion injury of the heart
J Mol Cell Cardiol, 78, 9-22
DOI 10.1016/j.yjmcc.2014.11.010, PubMed 25446179

Stensløkken KO, Ellefsen S, Vasieva O, Fang Y, Farrell AP, Olohan L, Vaage J, Nilsson GE, Cossins AR (2014)
Life without oxygen: gene regulatory responses of the crucian carp (Carassius carassius) heart subjected to chronic anoxia
PLoS One, 9 (11), e109978
DOI 10.1371/journal.pone.0109978, PubMed 25372666

Nilsson GE, Vaage J, Stensløkken KO (2014)
Oxygen- and temperature-dependent expression of survival protein kinases in crucian carp (Carassius carassius) heart and brain
Am J Physiol Regul Integr Comp Physiol, 308 (1), R50-61
DOI 10.1152/ajpregu.00094.2014, PubMed 25377478

Rutkovskiy A, Mariero LH, Vaage J (2014)
Deletion of the aquaporin-4 gene alters expression and phosphorylation of protective kinases in the mouse heart
Scand J Clin Lab Invest, 74 (6), 500-5
DOI 10.3109/00365513.2014.905698, PubMed 24792367

Wu X, Sagave J, Rutkovskiy A, Haugen F, Baysa A, Nygård S, Czibik G, Dahl CP, Gullestad L, Vaage J, Valen G (2014)
Expression of bone morphogenetic protein 4 and its receptors in the remodeling heart
Life Sci, 97 (2), 145-54
DOI 10.1016/j.lfs.2013.12.030, PubMed 24398041

Rutkovskiy A, Bliksøen M, Hillestad V, Amin M, Czibik G, Valen G, Vaage J, Amiry-Moghaddam M, Stensløkken KO (2012)
Aquaporin-1 in cardiac endothelial cells is downregulated in ischemia, hypoxia and cardioplegia
J Mol Cell Cardiol, 56, 22-33
DOI 10.1016/j.yjmcc.2012.12.002, PubMed 23238222

Troitskaya M, Baysa A, Vaage J, Sand KL, Maghazachi AA, Valen G (2012)
Interleukin-17 (IL-17) expression is reduced during acute myocardial infarction: role on chemokine receptor expression in monocytes and their in vitro chemotaxis towards chemokines
Toxins (Basel), 4 (12), 1427-39
DOI 10.3390/toxins4121427, PubMed 23202375

Rutkovskiy A, Mariero LH, Nygård S, Stensløkken KO, Valen G, Vaage J (2012)
Transient hyperosmolality modulates expression of cardiac aquaporins
Biochem Biophys Res Commun, 425 (1), 70-5
DOI 10.1016/j.bbrc.2012.07.052, PubMed 22820194

Rutkovskiy A, Stensløkken KO, Mariero LH, Skrbic B, Amiry-Moghaddam M, Hillestad V, Valen G, Perreault MC, Ottersen OP, Gullestad L, Dahl CP, Vaage J (2012)
Aquaporin-4 in the heart: expression, regulation and functional role in ischemia
Basic Res Cardiol, 107 (5), 280
DOI 10.1007/s00395-012-0280-6, PubMed 22777185

Mariero LH, Rutkovskiy A, Stensløkken KO, Vaage J (2012)
Hyperoxia during early reperfusion does not increase ischemia/reperfusion injury
Eur J Cardiothorac Surg, 41 (1), 149-53
DOI 10.1016/j.ejcts.2011.04.022, PubMed 21636285

Kaljusto ML, Rutkovsky A, Stensløkken KO, Vaage J (2010)
Postconditioning in mouse hearts is inhibited by blocking the reverse mode of the sodium-calcium exchanger
Interact Cardiovasc Thorac Surg, 10 (5), 743-8
DOI 10.1510/icvts.2009.217083, PubMed 20139199

Våge J, Wade C, Biagi T, Fatjó J, Amat M, Lindblad-Toh K, Lingaas F (2010)
Association of dopamine- and serotonin-related genes with canine aggression
Genes Brain Behav, 9 (4), 372-8
DOI 10.1111/j.1601-183X.2010.00568.x, PubMed 20132314

Stensløkken KO, Rutkovskiy A, Kaljusto ML, Hafstad AD, Larsen TS, Vaage J (2009)
Inadvertent phosphorylation of survival kinases in isolated perfused hearts: a word of caution
Basic Res Cardiol, 104 (4), 412-23
DOI 10.1007/s00395-009-0780-1, PubMed 19198917

Stensløkken KO, Ellefsen S, Stecyk JA, Dahl MB, Nilsson GE, Vaage J (2008)
Differential regulation of AMP-activated kinase and AKT kinase in response to oxygen availability in crucian carp (Carassius carassius)
Am J Physiol Regul Integr Comp Physiol, 295 (6), R1803-14
DOI 10.1152/ajpregu.90590.2008, PubMed 18922957

Czibik G, Wu Z, Berne GP, Tarkka M, Vaage J, Laurikka J, Järvinen O, Valen G (2008)
Human adaptation to ischemia by preconditioning or unstable angina: involvement of nuclear factor kappa B, but not hypoxia-inducible factor 1 alpha in the heart
Eur J Cardiothorac Surg, 34 (5), 976-84
DOI 10.1016/j.ejcts.2008.07.066, PubMed 18842422

Chen F, Eriksson P, Whatling C, Vaage J, Valen G (2008)
Surgical handling of saphenous vein grafts induces expression of matrix metalloproteinase 9
Scand Cardiovasc J, 42 (5), 327-36
DOI 10.1080/14017430801919540, PubMed 18609045

Bliksøen M, Kaljusto ML, Vaage J, Stensløkken KO (2008)
Effects of hydrogen sulphide on ischaemia-reperfusion injury and ischaemic preconditioning in the isolated, perfused rat heart
Eur J Cardiothorac Surg, 34 (2), 344-9
DOI 10.1016/j.ejcts.2008.03.017, PubMed 18455926

Kaljusto ML, Stensløkken KO, Mori T, Panchenko A, Frantzen ML, Valen G, Vaage J (2008)
Preconditioning effects of steroids and hyperoxia on cardiac ischemia-reperfusion injury and vascular reactivity
Eur J Cardiothorac Surg, 33 (3), 355-63
DOI 10.1016/j.ejcts.2007.12.017, PubMed 18221880

Vaage J (1994)
Microvascular injury induced by intravascular platelet aggregation. An experimental study
Scand J Thorac Cardiovasc Surg, 28 (3-4), 127-33
DOI 10.3109/14017439409099117, PubMed 7792557

Vaage J, Valen G (1991)
Could treatment with scavengers of oxygen free radicals minimize complications in cardiac surgery?
Klin Wochenschr, 69 (21-23), 1066-72
DOI 10.1007/BF01645160, PubMed 1798281

Vaage J, Semb AG (1989)
Myocardial reperfusion injury: an inflammatory reaction?
Biomed Biochim Acta, 48 (2-3), S63-8
PubMed 2786416

Vaage J (1982)
Intravascular platelet aggregation and pulmonary injury
Ann N Y Acad Sci, 384, 301-18
DOI 10.1111/j.1749-6632.1982.tb21380.x, PubMed 6953827

Vaage J (1976)
Vagal reflexes in the bronchoconstriction occurring after induced intravascular platelet aggregation
Acta Physiol Scand, 97 (1), 94-103
DOI 10.1111/j.1748-1716.1976.tb10239.x, PubMed 5852

Review articles

Torp MK, Stensløkken KO, Vaage J (2024)
When Our Best Friend Becomes Our Worst Enemy: The Mitochondrion in Trauma, Surgery, and Critical Illness
J Intensive Care Med, 8850666241237715 (in press)
DOI 10.1177/08850666241237715, PubMed 38505947

Torp MK, Vaage J, Stensløkken KO (2023)
Mitochondria-derived damage-associated molecular patterns and inflammation in the ischemic-reperfused heart
Acta Physiol (Oxf), 237 (3), e13920
DOI 10.1111/apha.13920, PubMed 36617670

Bogdanova M, Zabirnyk A, Malashicheva A, Semenova D, Kvitting JP, Kaljusto ML, Perez MDM, Kostareva A, Stensløkken KO, Sullivan GJ, Rutkovskiy A, Vaage J (2022)
Models and Techniques to Study Aortic Valve Calcification in Vitro, ex Vivo and in Vivo. An Overview
Front Pharmacol, 13, 835825
DOI 10.3389/fphar.2022.835825, PubMed 35721220

Rutkovskiy A, Malashicheva A, Sullivan G, Bogdanova M, Kostareva A, Stensløkken KO, Fiane A, Vaage J (2017)
Valve Interstitial Cells: The Key to Understanding the Pathophysiology of Heart Valve Calcification
J Am Heart Assoc, 6 (9)
DOI 10.1161/JAHA.117.006339, PubMed 28912209

Rutkovskiy A, Valen G, Vaage J (2013)
Cardiac aquaporins
Basic Res Cardiol, 108 (6), 393
DOI 10.1007/s00395-013-0393-6, PubMed 24158693