Publication list - Publika - Scientific publications from Oslo University Hospital

Publications by Lars Krogvold

51 publications found

Original articles

Buschard K, Josefsen K, Krogvold L, Gerling I, Dahl-Jørgensen K, Pociot F (2024)
Influence of sphingolipid enzymes on blood glucose levels, development of diabetes, and involvement of pericytes
Diabetes Metab Res Rev, 40 (3), e3792
DOI 10.1002/dmrr.3792, PubMed 38517704

Svalastoga P, Kaci A, Molnes J, Solheim MH, Johansson BB, Krogvold L, Skrivarhaug T, Valen E, Johansson S, Molven A, Sagen JV, Søfteland E, Bjørkhaug L, Tjora E, Aukrust I, Njølstad PR (2023)
Characterisation of HNF1A variants in paediatric diabetes in Norway using functional and clinical investigations to unmask phenotype and monogenic diabetes
Diabetologia, 66 (12), 2226-2237
DOI 10.1007/s00125-023-06012-4, PubMed 37798422

Krogvold L, Mynarek IM, Ponzi E, Mørk FB, Hessel TW, Roald T, Lindblom N, Westman J, Barker P, Hyöty H, Ludvigsson J, Hanssen KF, Johannesen J, Dahl-Jørgensen K (2023)
Pleconaril and ribavirin in new-onset type 1 diabetes: a phase 2 randomized trial
Nat Med, 29 (11), 2902-2908
DOI 10.1038/s41591-023-02576-1, PubMed 37789144

Buschard K, Jensen MH, Krogvold L, Gerling IC, Dahl-Jørgensen K, Pedersen K, Haupt-Jorgensen M (2023)
Type 1 diabetes could begin with alterations in innate anti-viral immunity, which are already at this stage associated with HLA risk haplotypes
Diabetes Metab Res Rev, 39 (7), e3678
DOI 10.1002/dmrr.3678, PubMed 37395313

Josefsen K, Krogvold L, Gerling IC, Pociot F, Dahl-Jørgensen K, Buschard K (2022)
Development of Type 1 Diabetes may occur through a Type 2 Diabetes mechanism
Front Endocrinol (Lausanne), 13, 1032822
DOI 10.3389/fendo.2022.1032822, PubMed 36589856

Tekin H, Josefsen K, Krogvold L, Dahl-Jørgensen K, Gerling I, Pociot F, Buschard K (2022)
PDE12 in type 1 diabetes
Sci Rep, 12 (1), 18149
DOI 10.1038/s41598-022-22890-x, PubMed 36307540

Krogvold L, Genoni A, Puggioni A, Campani D, Richardson SJ, Flaxman CS, Edwin B, Buanes T, Dahl-Jørgensen K, Toniolo A (2022)
Live enteroviruses, but not other viruses, detected in human pancreas at the onset of type 1 diabetes in the DiViD study
Diabetologia, 65 (12), 2108-2120
DOI 10.1007/s00125-022-05779-2, PubMed 35953727

Krogvold L, Leete P, Mynarek IM, Russell MA, Gerling IC, Lenchik NI, Mathews C, Richardson SJ, Morgan NG, Dahl-Jørgensen K (2022)
Detection of Antiviral Tissue Responses and Increased Cell Stress in the Pancreatic Islets of Newly Diagnosed Type 1 Diabetes Patients: Results From the DiViD Study
Front Endocrinol (Lausanne), 13, 881997
DOI 10.3389/fendo.2022.881997, PubMed 35957810

Välikangas T, Lietzén N, Jaakkola MK, Krogvold L, Eike MC, Kallionpää H, Tuomela S, Mathews C, Gerling IC, Oikarinen S, Hyöty H, Dahl-Jorgensen K, Elo LL, Lahesmaa R (2022)
Pancreas Whole Tissue Transcriptomics Highlights the Role of the Exocrine Pancreas in Patients With Recently Diagnosed Type 1 Diabetes
Front Endocrinol (Lausanne), 13, 861985
DOI 10.3389/fendo.2022.861985, PubMed 35498413

Nigi L, Brusco N, Grieco GE, Fignani D, Licata G, Formichi C, Aiello E, Marselli L, Marchetti P, Krogvold L, Jorgensen KD, Sebastiani G, Dotta F (2022)
Increased Expression of Viral Sensor MDA5 in Pancreatic Islets and in Hormone-Negative Endocrine Cells in Recent Onset Type 1 Diabetic Donors
Front Immunol, 13, 833141
DOI 10.3389/fimmu.2022.833141, PubMed 35359976

Oikarinen S, Krogvold L, Edwin B, Buanes T, Korsgren O, Laiho JE, Oikarinen M, Ludvigsson J, Skog O, Anagandula M, Frisk G, Hyöty H, Dahl-Jørgensen K (2021)
Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study
Diabetologia, 64 (11), 2491-2501
DOI 10.1007/s00125-021-05525-0, PubMed 34390364

Pedersen K, Haupt-Jorgensen M, Krogvold L, Kaur S, Gerling IC, Pociot F, Dahl-Jørgensen K, Buschard K (2021)
Genetic predisposition in the 2'-5'A pathway in the development of type 1 diabetes: potential contribution to dysregulation of innate antiviral immunity
Diabetologia, 64 (8), 1805-1815
DOI 10.1007/s00125-021-05469-5, PubMed 33973017

Reddy S, Krogvold L, Martin C, Sun KX, Martin O, Al-Ani A, Dahl-Jørgensen K (2021)
Expression of immunoreactive inducible nitric oxide synthase in pancreatic islet cells from newly diagnosed and long-term type 1 diabetic donors is heterogeneous and not disease-associated
Cell Tissue Res, 384 (3), 655-674
DOI 10.1007/s00441-020-03340-4, PubMed 33427953

Rodriguez-Calvo T, Krogvold L, Amirian N, Dahl-Jørgensen K, von Herrath M (2021)
One in Ten CD8⁺ Cells in the Pancreas of Living Individuals With Recent-Onset Type 1 Diabetes Recognizes the Preproinsulin Epitope PPI_15-24
Diabetes, 70 (3), 752-758
DOI 10.2337/db20-0908, PubMed 33414250

Sever D, Hershko-Moshe A, Srivastava R, Eldor R, Hibsher D, Keren-Shaul H, Amit I, Bertuzzi F, Krogvold L, Dahl-Jørgensen K, Ben-Dov IZ, Landsman L, Melloul D (2021)
NF-κB activity during pancreas development regulates adult β-cell mass by modulating neonatal β-cell proliferation and apoptosis
Cell Death Discov, 7 (1), 2
DOI 10.1038/s41420-020-00386-9, PubMed 33414444

Nigi L, Brusco N, Grieco GE, Licata G, Krogvold L, Marselli L, Gysemans C, Overbergh L, Marchetti P, Mathieu C, Dahl Jørgensen K, Sebastiani G, Dotta F (2020)
Pancreatic Alpha-Cells Contribute Together With Beta-Cells to CXCL10 Expression in Type 1 Diabetes
Front Endocrinol (Lausanne), 11, 630
DOI 10.3389/fendo.2020.00630, PubMed 33042009

Colli ML, Ramos-Rodríguez M, Nakayasu ES, Alvelos MI, Lopes M, Hill JLE, Turatsinze JV, Coomans de Brachène A, Russell MA, Raurell-Vila H, Castela A, Juan-Mateu J, Webb-Robertson BM, Krogvold L, Dahl-Jorgensen K, Marselli L, Marchetti P, Richardson SJ, Morgan NG, Metz TO, Pasquali L, Eizirik DL (2020)
An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells
Nat Commun, 11 (1), 2584
DOI 10.1038/s41467-020-16327-0, PubMed 32444635

Rajendran S, Anquetil F, Quesada-Masachs E, Graef M, Gonzalez N, McArdle S, Chu T, Krogvold L, Dahl-Jørgensen K, von Herrath M (2019)
IL-6 is present in beta and alpha cells in human pancreatic islets: Expression is reduced in subjects with type 1 diabetes
Clin Immunol, 211, 108320
DOI 10.1016/j.clim.2019.108320, PubMed 31809899

Seiron P, Wiberg A, Kuric E, Krogvold L, Jahnsen FL, Dahl-Jørgensen K, Skog O, Korsgren O (2019)
Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced
J Pathol Clin Res, 5 (4), 248-255
DOI 10.1002/cjp2.140, PubMed 31493350

Russell MA, Redick SD, Blodgett DM, Richardson SJ, Leete P, Krogvold L, Dahl-Jørgensen K, Bottino R, Brissova M, Spaeth JM, Babon JAB, Haliyur R, Powers AC, Yang C, Kent SC, Derr AG, Kucukural A, Garber MG, Morgan NG, Harlan DM (2019)
HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of Islet β-Cells From Donors With Type 1 Diabetes
Diabetes, 68 (5), 988-1001
DOI 10.2337/db18-0686, PubMed 30833470

Colli ML, Hill JLE, Marroquí L, Chaffey J, Dos Santos RS, Leete P, Coomans de Brachène A, Paula FMM, Op de Beeck A, Castela A, Marselli L, Krogvold L, Dahl-Jorgensen K, Marchetti P, Morgan NG, Richardson SJ, Eizirik DL (2018)
PDL1 is expressed in the islets of people with type 1 diabetes and is up-regulated by interferons-α and-γ via IRF1 induction
EBioMedicine, 36, 367-375
DOI 10.1016/j.ebiom.2018.09.040, PubMed 30269996

Vecchio F, Lo Buono N, Stabilini A, Nigi L, Dufort MJ, Geyer S, Rancoita PM, Cugnata F, Mandelli A, Valle A, Leete P, Mancarella F, Linsley PS, Krogvold L, Herold KC, Elding Larsson H, Richardson SJ, Morgan NG, Dahl-Jørgensen K, Sebastiani G, Dotta F, Bosi E, DRI_Biorepository Group, Type 1 Diabetes TrialNet Study Group, Battaglia M (2018)
Abnormal neutrophil signature in the blood and pancreas of presymptomatic and symptomatic type 1 diabetes
JCI Insight, 3 (18)
DOI 10.1172/jci.insight.122146, PubMed 30232284

Horwitz E, Krogvold L, Zhitomirsky S, Swisa A, Fischman M, Lax T, Dahan T, Hurvitz N, Weinberg-Corem N, Klochendler A, Powers AC, Brissova M, Jörns A, Lenzen S, Glaser B, Dahl-Jørgensen K, Dor Y (2018)
β-Cell DNA Damage Response Promotes Islet Inflammation in Type 1 Diabetes
Diabetes, 67 (11), 2305-2318
DOI 10.2337/db17-1006, PubMed 30150306

Anquetil F, Mondanelli G, Gonzalez N, Rodriguez Calvo T, Zapardiel Gonzalo J, Krogvold L, Dahl-Jørgensen K, Van den Eynde B, Orabona C, Grohmann U, von Herrath MG (2018)
Loss of IDO1 Expression From Human Pancreatic β-Cells Precedes Their Destruction During the Development of Type 1 Diabetes
Diabetes, 67 (9), 1858-1866
DOI 10.2337/db17-1281, PubMed 29945890

Kuric E, Krogvold L, Hanssen KF, Dahl-Jørgensen K, Skog O, Korsgren O (2018)
No Evidence for Presence of Mucosal-Associated Invariant T Cells in the Insulitic Lesions in Patients Recently Diagnosed with Type 1 Diabetes
Am J Pathol, 188 (8), 1744-1748
DOI 10.1016/j.ajpath.2018.04.009, PubMed 29803829

Holm LJ, Krogvold L, Hasselby JP, Kaur S, Claessens LA, Russell MA, Mathews CE, Hanssen KF, Morgan NG, Koeleman BPC, Roep BO, Gerling IC, Pociot F, Dahl-Jørgensen K, Buschard K (2018)
Abnormal islet sphingolipid metabolism in type 1 diabetes
Diabetologia, 61 (7), 1650-1661
DOI 10.1007/s00125-018-4614-2, PubMed 29671030

Reddy S, Krogvold L, Martin C, Holland R, Choi J, Woo H, Wu F, Dahl-Jørgensen K (2018)
Distribution of IL-1β immunoreactive cells in pancreatic biopsies from living volunteers with new-onset type 1 diabetes: comparison with donors without diabetes and with longer duration of disease
Diabetologia, 61 (6), 1362-1373
DOI 10.1007/s00125-018-4600-8, PubMed 29589071

Lundberg M, Lindqvist A, Wierup N, Krogvold L, Dahl-Jørgensen K, Skog O (2017)
The density of parasympathetic axons is reduced in the exocrine pancreas of individuals recently diagnosed with type 1 diabetes
PLoS One, 12 (6), e0179911
DOI 10.1371/journal.pone.0179911, PubMed 28628651

Kosfeld A, Brand F, Weiss AC, Kreuzer M, Goerk M, Martens H, Schubert S, Schäfer AK, Riehmer V, Hennies I, Bräsen JH, Pape L, Amann K, Krogvold L, Bjerre A, Daniel C, Kispert A, Haffner D, Weber RG (2017)
Mutations in the leukemia inhibitory factor receptor (LIFR) gene and Lifr deficiency cause urinary tract malformations
Hum Mol Genet, 26 (9), 1716-1731
DOI 10.1093/hmg/ddx086, PubMed 28334964

Kuric E, Seiron P, Krogvold L, Edwin B, Buanes T, Hanssen KF, Skog O, Dahl-Jørgensen K, Korsgren O (2017)
Demonstration of Tissue Resident Memory CD8 T Cells in Insulitic Lesions in Adult Patients with Recent-Onset Type 1 Diabetes
Am J Pathol, 187 (3), 581-588
DOI 10.1016/j.ajpath.2016.11.002, PubMed 28212742

Martin C, Krogvold L, Farik S, Amirapu S, Wu F, Reddy S, Dahl-Jørgensen K (2017)
An immunohistochemical study of nitrotyrosine expression in pancreatic islets of cases with increasing duration of type 1 diabetes and without diabetes
Histochem Cell Biol, 147 (5), 605-623
DOI 10.1007/s00418-016-1533-5, PubMed 28154952

Rodriguez-Calvo T, Zapardiel-Gonzalo J, Amirian N, Castillo E, Lajevardi Y, Krogvold L, Dahl-Jørgensen K, von Herrath MG (2017)
Increase in Pancreatic Proinsulin and Preservation of β-Cell Mass in Autoantibody-Positive Donors Prior to Type 1 Diabetes Onset
Diabetes, 66 (5), 1334-1345
DOI 10.2337/db16-1343, PubMed 28137793

Hodik M, Anagandula M, Fuxe J, Krogvold L, Dahl-Jørgensen K, Hyöty H, Sarmiento L, Frisk G, POD-V Consortium (2016)
Coxsackie-adenovirus receptor expression is enhanced in pancreas from patients with type 1 diabetes
BMJ Open Diabetes Res Care, 4 (1), e000219
DOI 10.1136/bmjdrc-2016-000219, PubMed 27933184

Richardson SJ, Rodriguez-Calvo T, Gerling IC, Mathews CE, Kaddis JS, Russell MA, Zeissler M, Leete P, Krogvold L, Dahl-Jørgensen K, von Herrath M, Pugliese A, Atkinson MA, Morgan NG (2016)
Islet cell hyperexpression of HLA class I antigens: a defining feature in type 1 diabetes
Diabetologia, 59 (11), 2448-2458
DOI 10.1007/s00125-016-4067-4, PubMed 27506584

Lundberg M, Krogvold L, Kuric E, Dahl-Jørgensen K, Skog O (2016)
Expression of Interferon-Stimulated Genes in Insulitic Pancreatic Islets of Patients Recently Diagnosed With Type 1 Diabetes
Diabetes, 65 (10), 3104-10
DOI 10.2337/db16-0616, PubMed 27422384

Leete P, Willcox A, Krogvold L, Dahl-Jørgensen K, Foulis AK, Richardson SJ, Morgan NG (2016)
Differential Insulitic Profiles Determine the Extent of β-Cell Destruction and the Age at Onset of Type 1 Diabetes
Diabetes, 65 (5), 1362-9
DOI 10.2337/db15-1615, PubMed 26858360

Krogvold L, Wiberg A, Edwin B, Buanes T, Jahnsen FL, Hanssen KF, Larsson E, Korsgren O, Skog O, Dahl-Jørgensen K (2015)
Insulitis and characterisation of infiltrating T cells in surgical pancreatic tail resections from patients at onset of type 1 diabetes
Diabetologia, 59 (3), 492-501
DOI 10.1007/s00125-015-3820-4, PubMed 26602422

Krogvold L, Skog O, Sundström G, Edwin B, Buanes T, Hanssen KF, Ludvigsson J, Grabherr M, Korsgren O, Dahl-Jørgensen K (2015)
Function of Isolated Pancreatic Islets From Patients at Onset of Type 1 Diabetes: Insulin Secretion Can Be Restored After Some Days in a Nondiabetogenic Environment In Vitro: Results From the DiViD Study
Diabetes, 64 (7), 2506-12
DOI 10.2337/db14-1911, PubMed 25677915

Skog O, Korsgren S, Wiberg A, Danielsson A, Edwin B, Buanes T, Krogvold L, Korsgren O, Dahl-Jørgensen K (2015)
Expression of human leukocyte antigen class I in endocrine and exocrine pancreatic tissue at onset of type 1 diabetes
Am J Pathol, 185 (1), 129-38
DOI 10.1016/j.ajpath.2014.09.004, PubMed 25524212

Krogvold L, Edwin B, Buanes T, Frisk G, Skog O, Anagandula M, Korsgren O, Undlien D, Eike MC, Richardson SJ, Leete P, Morgan NG, Oikarinen S, Oikarinen M, Laiho JE, Hyöty H, Ludvigsson J, Hanssen KF, Dahl-Jørgensen K (2014)
Detection of a low-grade enteroviral infection in the islets of langerhans of living patients newly diagnosed with type 1 diabetes
Diabetes, 64 (5), 1682-7
DOI 10.2337/db14-1370, PubMed 25422108

Krogvold L, Henrichsen T, Bjerre A, Brackman D, Dollner H, Gudmundsdottir H, Syversen G, Næss PA, Bangstad HJ (2011)
Clinical aspects of a nationwide epidemic of severe haemolytic uremic syndrome (HUS) in children
Scand J Trauma Resusc Emerg Med, 19, 44
DOI 10.1186/1757-7241-19-44, PubMed 21798000

Fluge S, Kaspersen T, Knudsen EC, Krogvold L, Sigstad E, Try K, Førde R (1994)
[Children and health. A questionnaire survey of 12-year-old children]
Tidsskr Nor Laegeforen, 114 (17), 1938-40
PubMed 8079321

Tveten Y, Ahlquist J, Krogvold L, Bruu AL, Størvold G, Orstavik I (1994)
Restriction endonuclease analysis of adenovirus type 3 isolated in Norway from 1970 to 1991
APMIS, 102 (3), 215-8
DOI 10.1111/j.1699-0463.1994.tb04867.x, PubMed 8185888

Review articles

Deeb A, Elbarbary N, Smart CE, Beshyah SA, Habeb A, Kalra S, Al Alwan I, Babiker A, Al Amoudi R, Pulungan AB, Humayun K, Issa U, Jalaludin MY, Sanhay R, Akanov Z, Krogvold L, de Beaufort C (2019)
ISPAD Clinical Practice Consensus Guidelines: Fasting during Ramadan by young people with diabetes
Pediatr Diabetes, 21 (1), 5-17
DOI 10.1111/pedi.12920, PubMed 31659852

Krogvold L, Wathne KO (2004)
[Treatment of serious infectious diseases in children]
Tidsskr Nor Laegeforen, 124 (4), 484-7
PubMed 14983194