RSS feed

Publications by Christine Ellingsen

28 publications found

Original articles

Zitzmann-Kolbe S, Kristian A, Zopf D, Kamfenkel C, Politz O, Ellingsen C, Hilbig J, Juul MU, Fonslet J, Nielsen CH, Schatz CA, Bjerke RM, Cuthbertson AS, Mumberg D, Hagemann UB (2023)
A Targeted Thorium-227 Conjugate Demonstrates Efficacy in Preclinical Models of Acquired Drug Resistance and Combination Potential with Chemotherapeutics and Antiangiogenic Therapies
Mol Cancer Ther, 22 (9), 1073-1086
DOI 10.1158/1535-7163.MCT-22-0808, PubMed 37365121

Karlsson J, Hagemann UB, Cruciani V, Schatz CA, Grant D, Ellingsen C, Kristian A, Katoozi S, Mihaylova D, Uran SR, Suominen M, Bjerke RM, Ryan OB, Cuthbertson A (2023)
Efficacy of a HER2-Targeted Thorium-227 Conjugate in a HER2-Positive Breast Cancer Bone Metastasis Model
Cancers (Basel), 15 (13)
DOI 10.3390/cancers15133419, PubMed 37444529

Broer LN, Knapen DG, Suurs FV, Moen I, Giesen D, Waaijer SJH, Indrevoll B, Ellingsen C, Kristian A, Cuthbertson AS, de Groot DA, Cole PE, de Vries EGE, Hagemann UB, Lub-de Hooge MN (2022)
⁸⁹Zr-3,2-HOPO-Mesothelin Antibody PET Imaging Reflects Tumor Uptake of Mesothelin-Targeted ²²⁷Th-Conjugate Therapy in Mice
J Nucl Med, 63 (11), 1715-1721
DOI 10.2967/jnumed.121.263079, PubMed 35422447

Hammer S, Schlicker A, Zitzmann-Kolbe S, Baumgart S, Hagemann UB, Scholz A, Haendler B, Lejeune P, Karlsson J, Ellingsen C, Hennekes H, Nielsen CH, Juul MU, Mumberg D, Schatz CA (2021)
Darolutamide Potentiates the Antitumor Efficacy of a PSMA-targeted Thorium-227 Conjugate by a Dual Mode of Action in Prostate Cancer Models
Clin Cancer Res, 27 (15), 4367-4378
DOI 10.1158/1078-0432.CCR-21-0342, PubMed 34035067

Hammer S, Hagemann UB, Zitzmann-Kolbe S, Larsen A, Ellingsen C, Geraudie S, Grant D, Indrevoll B, Smeets R, von Ahsen O, Kristian A, Lejeune P, Hennekes H, Karlsson J, Bjerke RM, Ryan OB, Cuthbertson AS, Mumberg D (2019)
Preclinical Efficacy of a PSMA-Targeted Thorium-227 Conjugate (PSMA-TTC), a Targeted Alpha Therapy for Prostate Cancer
Clin Cancer Res, 26 (8), 1985-1996
DOI 10.1158/1078-0432.CCR-19-2268, PubMed 31831560

Wickstroem K, Karlsson J, Ellingsen C, Cruciani V, Kristian A, Hagemann UB, Bjerke RM, Ryan OB, Linden L, Mumberg D, Brands M, Cuthbertson A (2019)
Synergistic Effect of a HER2 Targeted Thorium-227 Conjugate in Combination with Olaparib in a BRCA2 Deficient Xenograft Model
Pharmaceuticals (Basel), 12 (4)
DOI 10.3390/ph12040155, PubMed 31618864

Wickstroem K, Hagemann UB, Kristian A, Ellingsen C, Sommer A, Ellinger-Ziegelbauer H, Wirnitzer U, Hagelin EM, Larsen A, Smeets R, Bjerke RM, Karlsson J, Ryan OB, Wengner AM, Linden L, Mumberg D, Cuthbertson AS (2019)
Preclinical Combination Studies of an FGFR2 Targeted Thorium-227 Conjugate and the ATR Inhibitor BAY 1895344
Int J Radiat Oncol Biol Phys, 105 (2), 410-422
DOI 10.1016/j.ijrobp.2019.06.2508, PubMed 31255687

Hagemann UB, Ellingsen C, Schuhmacher J, Kristian A, Mobergslien A, Cruciani V, Wickstroem K, Schatz CA, Kneip C, Golfier S, Smeets R, Uran S, Hennekes H, Karlsson J, Bjerke RM, Ryan OB, Mumberg D, Ziegelbauer K, Cuthbertson AS (2019)
Mesothelin-Targeted Thorium-227 Conjugate (MSLN-TTC): Preclinical Evaluation of a New Targeted Alpha Therapy for Mesothelin-Positive Cancers
Clin Cancer Res, 25 (15), 4723-4734
DOI 10.1158/1078-0432.CCR-18-3476, PubMed 31064781

Wickstroem K, Hagemann UB, Cruciani V, Wengner AM, Kristian A, Ellingsen C, Siemeister G, Bjerke RM, Karlsson J, Ryan OB, Linden L, Mumberg D, Ziegelbauer K, Cuthbertson AS (2019)
Synergistic Effect of a Mesothelin-Targeted ²²⁷Th Conjugate in Combination with DNA Damage Response Inhibitors in Ovarian Cancer Xenograft Models
J Nucl Med, 60 (9), 1293-1300
DOI 10.2967/jnumed.118.223701, PubMed 30850485

Rofstad EK, Simonsen TG, Huang R, Andersen LM, Galappathi K, Ellingsen C, Wegner CS, Hauge A, Gaustad JV (2016)
Patient-derived xenograft models of squamous cell carcinoma of the uterine cervix
Cancer Lett, 373 (2), 147-55
DOI 10.1016/j.canlet.2016.01.047, PubMed 26828134

Ellingsen C, Andersen LM, Galappathi K, Rofstad EK (2015)
Hypoxia biomarkers in squamous cell carcinoma of the uterine cervix
BMC Cancer, 15, 805
DOI 10.1186/s12885-015-1828-2, PubMed 26502718

Gorad SS, Ellingsen C, Bathen TF, Mathiesen BS, Moestue SA, Rofstad EK (2015)
Identification of Metastasis-Associated Metabolic Profiles of Tumors by (1)H-HR-MAS-MRS
Neoplasia, 17 (10), 767-75
DOI 10.1016/j.neo.2015.10.001, PubMed 26585232

Hompland T, Lund KV, Ellingsen C, Kristensen GB, Rofstad EK (2014)
Peritumoral interstitial fluid flow velocity predicts survival in cervical carcinoma
Radiother Oncol, 113 (1), 132-8
DOI 10.1016/j.radonc.2014.09.011, PubMed 25443501

Hompland T, Ellingsen C, Galappathi K, Rofstad EK (2014)
DW-MRI in assessment of the hypoxic fraction, interstitial fluid pressure, and metastatic propensity of melanoma xenografts
BMC Cancer, 14, 92
DOI 10.1186/1471-2407-14-92, PubMed 24528854

Ellingsen C, Hompland T, Galappathi K, Mathiesen B, Rofstad EK (2013)
DCE-MRI of the hypoxic fraction, radioresponsiveness, and metastatic propensity of cervical carcinoma xenografts
Radiother Oncol, 110 (2), 335-41
DOI 10.1016/j.radonc.2013.10.018, PubMed 24231244

Ellingsen C, Walenta S, Hompland T, Mueller-Klieser W, Rofstad EK (2013)
The Microenvironment of Cervical Carcinoma Xenografts: Associations with Lymph Node Metastasis and Its Assessment by DCE-MRI
Transl Oncol, 6 (5), 607-17
DOI 10.1593/tlo.13313, PubMed 24151541

Hompland T, Ellingsen C, Galappathi K, Rofstad EK (2013)
Connective tissue of cervical carcinoma xenografts: associations with tumor hypoxia and interstitial fluid pressure and its assessment by DCE-MRI and DW-MRI
Acta Oncol, 53 (1), 6-15
DOI 10.3109/0284186X.2013.773073, PubMed 23445339

Hompland T, Ellingsen C, Rofstad EK (2012)
Preclinical evaluation of Gd-DTPA and gadomelitol as contrast agents in DCE-MRI of cervical carcinoma interstitial fluid pressure
BMC Cancer, 12, 544
DOI 10.1186/1471-2407-12-544, PubMed 23173554

Hompland T, Gulliksrud K, Ellingsen C, Rofstad EK (2012)
Assessment of the interstitial fluid pressure of tumors by dynamic contrast-enhanced magnetic resonance imaging with contrast agents of different molecular weights
Acta Oncol, 52 (3), 627-35
DOI 10.3109/0284186X.2012.737931, PubMed 23126523

Hompland T, Ellingsen C, Øvrebø KM, Rofstad EK (2012)
Interstitial fluid pressure and associated lymph node metastasis revealed in tumors by dynamic contrast-enhanced MRI
Cancer Res, 72 (19), 4899-908
DOI 10.1158/0008-5472.CAN-12-0903, PubMed 23027087

Øvrebø KM, Ellingsen C, Hompland T, Rofstad EK (2012)
Dynamic contrast-enhanced magnetic resonance imaging of the metastatic potential of tumors: a preclinical study of cervical carcinoma and melanoma xenografts
Acta Oncol, 52 (3), 604-11
DOI 10.3109/0284186X.2012.689851, PubMed 22671573

Ovrebø KM, Ellingsen C, Galappathi K, Rofstad EK (2012)
Dynamic contrast-enhanced magnetic resonance imaging of the metastatic potential of melanoma xenografts
Int J Radiat Oncol Biol Phys, 83 (1), e121-7
DOI 10.1016/j.ijrobp.2011.12.019, PubMed 22381901

Ellingsen C, Hompland T, Mathiesen B, Rofstad EK (2012)
Microenvironment-associated lymph node metastasis of human cervical carcinoma xenografts
Acta Oncol, 51 (4), 465-72
DOI 10.3109/0284186X.2011.636751, PubMed 22292610

Ellingsen C, Ovrebø KM, Galappathi K, Mathiesen B, Rofstad EK (2012)
pO₂ fluctuation pattern and cycling hypoxia in human cervical carcinoma and melanoma xenografts
Int J Radiat Oncol Biol Phys, 83 (4), 1317-23
DOI 10.1016/j.ijrobp.2011.09.037, PubMed 22270159

Ellingsen C, Egeland TA, Galappathi K, Rofstad EK (2010)
Dynamic contrast-enhanced magnetic resonance imaging of human cervical carcinoma xenografts: pharmacokinetic analysis and correlation to tumor histomorphology
Radiother Oncol, 97 (2), 217-24
DOI 10.1016/j.radonc.2010.06.011, PubMed 20656365

Egeland TA, Simonsen TG, Gaustad JV, Gulliksrud K, Ellingsen C, Rofstad EK (2009)
Dynamic contrast-enhanced magnetic resonance imaging of tumors: preclinical validation of parametric images
Radiat Res, 172 (3), 339-47
DOI 10.1667/RR1787.1, PubMed 19708783

Ellingsen C, Egeland TA, Gulliksrud K, Gaustad JV, Mathiesen B, Rofstad EK (2009)
Assessment of hypoxia in human cervical carcinoma xenografts by dynamic contrast-enhanced magnetic resonance imaging
Int J Radiat Oncol Biol Phys, 73 (3), 838-45
DOI 10.1016/j.ijrobp.2008.10.062, PubMed 19215820

Ellingsen C, Natvig I, Gaustad JV, Gulliksrud K, Egeland TA, Rofstad EK (2009)
Human cervical carcinoma xenograft models for studies of the physiological microenvironment of tumors
J Cancer Res Clin Oncol, 135 (9), 1177-84
DOI 10.1007/s00432-009-0558-8, PubMed 19214568