Publication list - Publika - Scientific publications from Oslo University Hospital

Publications by Roger Simm

46 publications found

Original articles

Hussain B, Simm R, Bueno J, Giannettou S, Naemi AO, Lyngstadaas SP, Haugen HJ (2024)
Biofouling on titanium implants: a novel formulation of poloxamer and peroxide for in situ removal of pellicle and multi-species oral biofilm
Regen Biomater, 11, rbae014
DOI 10.1093/rb/rbae014, PubMed 38435376

Cimdins-Ahne A, Naemi AO, Li F, Simm R, Römling U (2023)
Characterisation of Variants of Cyclic di-GMP Turnover Proteins Associated with Semi-Constitutive rdar Morphotype Expression in Commensal and Uropathogenic Escherichia coli Strains
Microorganisms, 11 (8)
DOI 10.3390/microorganisms11082048, PubMed 37630608

Munir A, Marovic D, Nogueira LP, Simm R, Naemi AO, Landrø SM, Helgerud M, Zheng K, Par M, Tauböck TT, Attin T, Tarle Z, Boccaccini AR, Haugen HJ (2022)
Using Copper-Doped Mesoporous Bioactive Glass Nanospheres to Impart Anti-Bacterial Properties to Dental Composites
Pharmaceutics, 14 (10)
DOI 10.3390/pharmaceutics14102241, PubMed 36297676

Rørvik GH, Naemi AO, Edvardsen PKT, Simm R (2021)
The c-di-AMP signaling system influences stress tolerance and biofilm formation of Streptococcus mitis
Microbiologyopen, 10 (4), e1203
DOI 10.1002/mbo3.1203, PubMed 34459556

Rørvik GH, Liskiewicz KA, Kryuchkov F, Naemi AO, Aasheim HC, Petersen FC, Küntziger TM, Simm R (2020)
Cyclic Di-adenosine Monophosphate Regulates Metabolism and Growth in the Oral Commensal Streptococcus mitis
Microorganisms, 8 (9)
DOI 10.3390/microorganisms8091269, PubMed 32825526

Kaspersen H, Fiskebeck EZ, Sekse C, Slettemeås JS, Urdahl AM, Norström M, Lagesen K, Simm R (2020)
Comparative Genome Analyses of Wild Type- and Quinolone Resistant Escherichia coli Indicate Dissemination of QREC in the Norwegian Broiler Breeding Pyramid
Front Microbiol, 11, 938
DOI 10.3389/fmicb.2020.00938, PubMed 32508776

Kaspersen H, Sekse C, Zeyl Fiskebeck E, Slettemeås JS, Simm R, Norström M, Urdahl AM, Lagesen K (2020)
Dissemination of Quinolone-Resistant Escherichia coli in the Norwegian Broiler and Pig Production Chains and Possible Persistence in the Broiler Production Environment
Appl Environ Microbiol, 86 (7)
DOI 10.1128/AEM.02769-19, PubMed 31953334

Naemi AO, Dey H, Kiran N, Sandvik ST, Slettemeås JS, Nesse LL, Simm R (2020)
NarAB Is an ABC-Type Transporter That Confers Resistance to the Polyether Ionophores Narasin, Salinomycin, and Maduramicin, but Not Monensin
Front Microbiol, 11, 104
DOI 10.3389/fmicb.2020.00104, PubMed 32117133

Simm R, Slettemeås JS, Norström M, Dean KR, Kaldhusdal M, Urdahl AM (2019)
Significant reduction of vancomycin resistant E. faecium in the Norwegian broiler population coincided with measures taken by the broiler industry to reduce antimicrobial resistant bacteria
PLoS One, 14 (12), e0226101
DOI 10.1371/journal.pone.0226101, PubMed 31830083

Paulsen B, Fredriksen KA, Petersen D, Maes L, Matheeussen A, Naemi AO, Scheie AA, Simm R, Ma R, Wan B, Franzblau S, Gundersen LL (2019)
Synthesis and antimicrobial activities of N⁶-hydroxyagelasine analogs and revision of the structure of ageloximes
Bioorg Med Chem, 27 (4), 620-629
DOI 10.1016/j.bmc.2019.01.002, PubMed 30638761

Kaspersen H, Urdahl AM, Simm R, Slettemeås JS, Lagesen K, Norström M (2018)
Occurrence of quinolone resistant E. coli originating from different animal species in Norway
Vet Microbiol, 217, 25-31
DOI 10.1016/j.vetmic.2018.02.022, PubMed 29615252

Cimdins A, Simm R, Li F, Lüthje P, Thorell K, Sjöling Å, Brauner A, Römling U (2017)
Alterations of c-di-GMP turnover proteins modulate semi-constitutive rdar biofilm formation in commensal and uropathogenic Escherichia coli
Microbiologyopen, 6 (5)
DOI 10.1002/mbo3.508, PubMed 28913868

Hassan KA, Fagerlund A, Elbourne LDH, Vörös A, Kroeger JK, Simm R, Tourasse NJ, Finke S, Henderson PJF, Økstad OA, Paulsen IT, Kolstø AB (2017)
The putative drug efflux systems of the Bacillus cereus group
PLoS One, 12 (5), e0176188
DOI 10.1371/journal.pone.0176188, PubMed 28472044

Simm R, Kvalvaag AS, van Deurs B, Lindbäck T, Sandvig K (2017)
Benzyl alcohol induces a reversible fragmentation of the Golgi apparatus and inhibits membrane trafficking between endosomes and the trans-Golgi network
Exp Cell Res, 357 (1), 67-78
DOI 10.1016/j.yexcr.2017.04.025, PubMed 28450044

Cimdins A, Simm R (2017)
Semiquantitative Analysis of the Red, Dry, and Rough Colony Morphology of Salmonella enterica Serovar Typhimurium and Escherichia coli Using Congo Red
Methods Mol Biol, 1657, 225-241
DOI 10.1007/978-1-4939-7240-1_18, PubMed 28889298

Kroeger JK, Hassan K, Vörös A, Simm R, Saidijam M, Bettaney KE, Bechthold A, Paulsen IT, Henderson PJ, Kolstø AB (2015)
Bacillus cereus eﬄux protein BC3310 - a multidrug transporter of the unknown major facilitator family, UMF-2
Front Microbiol, 6, 1063
DOI 10.3389/fmicb.2015.01063, PubMed 26528249

Kymre L, Simm R, Skotland T, Sandvig K (2015)
Different roles of the C-terminal end of Stx1A and Stx2A for AB5 complex integrity and retrograde transport of Stx in HeLa cells
Pathog Dis, 73 (9), ftv083
DOI 10.1093/femspd/ftv083, PubMed 26443836

Kavaliauskiene S, Skotland T, Sylvänne T, Simolin H, Klokk TI, Torgersen ML, Lingelem AB, Simm R, Ekroos K, Sandvig K (2015)
Novel actions of 2-deoxy-D-glucose: protection against Shiga toxins and changes in cellular lipids
Biochem J, 470 (1), 23-37
DOI 10.1042/BJ20141562, PubMed 26251444

Dyve Lingelem AB, Hjelseth IA, Simm R, Torgersen ML, Sandvig K (2015)
Geldanamycin Enhances Retrograde Transport of Shiga Toxin in HEp-2 Cells
PLoS One, 10 (5), e0129214
DOI 10.1371/journal.pone.0129214, PubMed 26017782

Le Guyon S, Simm R, Rehn M, Römling U (2015)
Dissecting the cyclic di-guanylate monophosphate signalling network regulating motility in Salmonella enterica serovar Typhimurium
Environ Microbiol, 17 (4), 1310-20
DOI 10.1111/1462-2920.12580, PubMed 25059628

Vörös A, Simm R, Slamti L, McKay MJ, Hegna IK, Nielsen-LeRoux C, Hassan KA, Paulsen IT, Lereclus D, Økstad OA, Molloy MP, Kolstø AB (2014)
SecDF as part of the Sec-translocase facilitates efficient secretion of Bacillus cereus toxins and cell wall-associated proteins
PLoS One, 9 (8), e103326
DOI 10.1371/journal.pone.0103326, PubMed 25083861

Bergan J, Skotland T, Lingelem AB, Simm R, Spilsberg B, Lindbäck T, Sylvänne T, Simolin H, Ekroos K, Sandvig K (2014)
The ether lipid precursor hexadecylglycerol protects against Shiga toxins
Cell Mol Life Sci, 71 (21), 4285-300
DOI 10.1007/s00018-014-1624-1, PubMed 24740796

Vörös A, Simm R, Kroeger JK, Kolstø AB (2013)
Gene transcription from the linear plasmid pBClin15 leads to cell lysis and extracellular DNA-dependent aggregation of Bacillus cereus ATCC 14579 in response to quinolone-induced stress
Microbiology (Reading), 159 (Pt 11), 2283-2293
DOI 10.1099/mic.0.069674-0, PubMed 24002748

Kavaliauskiene S, Nymark CM, Bergan J, Simm R, Sylvänne T, Simolin H, Ekroos K, Skotland T, Sandvig K (2013)
Cell density-induced changes in lipid composition and intracellular trafficking
Cell Mol Life Sci, 71 (6), 1097-116
DOI 10.1007/s00018-013-1441-y, PubMed 23921715

Kvalvaag AS, Pust S, Sundet KI, Engedal N, Simm R, Sandvig K (2013)
The ERM proteins ezrin and moesin regulate retrograde Shiga toxin transport
Traffic, 14 (7), 839-52
DOI 10.1111/tra.12077, PubMed 23593995

Backe PH, Simm R, Laerdahl JK, Dalhus B, Fagerlund A, Okstad OA, Rognes T, Alseth I, Kolstø AB, Bjørås M (2013)
A new family of proteins related to the HEAT-like repeat DNA glycosylases with affinity for branched DNA structures
J Struct Biol, 183 (1), 66-75
DOI 10.1016/j.jsb.2013.04.007, PubMed 23623903

Simm R, Vörös A, Ekman JV, Sødring M, Nes I, Kroeger JK, Saidijam M, Bettaney KE, Henderson PJ, Salkinoja-Salonen M, Kolstø AB (2012)
BC4707 is a major facilitator superfamily multidrug resistance transport protein from Bacillus cereus implicated in fluoroquinolone tolerance
PLoS One, 7 (5), e36720
DOI 10.1371/journal.pone.0036720, PubMed 22615800

Simm R, Remminghorst U, Ahmad I, Zakikhany K, Römling U (2009)
A role for the EAL-like protein STM1344 in regulation of CsgD expression and motility in Salmonella enterica serovar Typhimurium
J Bacteriol, 191 (12), 3928-37
DOI 10.1128/JB.00290-09, PubMed 19376870

Monteiro C, Saxena I, Wang X, Kader A, Bokranz W, Simm R, Nobles D, Chromek M, Brauner A, Brown RM, Römling U (2009)
Characterization of cellulose production in Escherichia coli Nissle 1917 and its biological consequences
Environ Microbiol, 11 (5), 1105-16
DOI 10.1111/j.1462-2920.2008.01840.x, PubMed 19175667

Simm R, Morr M, Remminghorst U, Andersson M, Römling U (2008)
Quantitative determination of cyclic diguanosine monophosphate concentrations in nucleotide extracts of bacteria by matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry
Anal Biochem, 386 (1), 53-8
DOI 10.1016/j.ab.2008.12.013, PubMed 19135022

Jonas K, Edwards AN, Simm R, Romeo T, Römling U, Melefors O (2008)
The RNA binding protein CsrA controls cyclic di-GMP metabolism by directly regulating the expression of GGDEF proteins
Mol Microbiol, 70 (1), 236-57
DOI 10.1111/j.1365-2958.2008.06411.x, PubMed 18713317

Meissner A, Wild V, Simm R, Rohde M, Erck C, Bredenbruch F, Morr M, Römling U, Häussler S (2007)
Pseudomonas aeruginosa cupA-encoded fimbriae expression is regulated by a GGDEF and EAL domain-dependent modulation of the intracellular level of cyclic diguanylate
Environ Microbiol, 9 (10), 2475-85
DOI 10.1111/j.1462-2920.2007.01366.x, PubMed 17803773

Rahman M, Simm R, Kader A, Basseres E, Römling U, Möllby R (2007)
The role of c-di-GMP signaling in an Aeromonas veronii biovar sobria strain
FEMS Microbiol Lett, 273 (2), 172-9
DOI 10.1111/j.1574-6968.2007.00803.x, PubMed 17573931

Simm R, Lusch A, Kader A, Andersson M, Römling U (2007)
Role of EAL-containing proteins in multicellular behavior of Salmonella enterica serovar Typhimurium
J Bacteriol, 189 (9), 3613-23
DOI 10.1128/JB.01719-06, PubMed 17322315

Ryjenkov DA, Simm R, Römling U, Gomelsky M (2006)
The PilZ domain is a receptor for the second messenger c-di-GMP: the PilZ domain protein YcgR controls motility in enterobacteria
J Biol Chem, 281 (41), 30310-4
DOI 10.1074/jbc.C600179200, PubMed 16920715

Kader A, Simm R, Gerstel U, Morr M, Römling U (2006)
Hierarchical involvement of various GGDEF domain proteins in rdar morphotype development of Salmonella enterica serovar Typhimurium
Mol Microbiol, 60 (3), 602-16
DOI 10.1111/j.1365-2958.2006.05123.x, PubMed 16629664

Simm R, Fetherston JD, Kader A, Römling U, Perry RD (2005)
Phenotypic convergence mediated by GGDEF-domain-containing proteins
J Bacteriol, 187 (19), 6816-23
DOI 10.1128/JB.187.19.6816-6823.2005, PubMed 16166544

Römling U, Kader A, Sriramulu DD, Simm R, Kronvall G (2005)
Worldwide distribution of Pseudomonas aeruginosa clone C strains in the aquatic environment and cystic fibrosis patients
Environ Microbiol, 7 (7), 1029-38
DOI 10.1111/j.1462-2920.2005.00780.x, PubMed 15946300

Simm R, Morr M, Kader A, Nimtz M, Römling U (2004)
GGDEF and EAL domains inversely regulate cyclic di-GMP levels and transition from sessility to motility
Mol Microbiol, 53 (4), 1123-34
DOI 10.1111/j.1365-2958.2004.04206.x, PubMed 15306016

Review articles

Frederiksen RF, Slettemeås JS, Granstad S, Lagesen K, Pikkemaat MG, Urdahl AM, Simm R (2024)
Polyether ionophore resistance in a one health perspective
Front Microbiol, 15, 1347490
DOI 10.3389/fmicb.2024.1347490, PubMed 38351920

Vestby LK, Grønseth T, Simm R, Nesse LL (2020)
Bacterial Biofilm and its Role in the Pathogenesis of Disease
Antibiotics (Basel), 9 (2)
DOI 10.3390/antibiotics9020059, PubMed 32028684

Nesse LL, Simm R (2018)
Biofilm: A Hotspot for Emerging Bacterial Genotypes
Adv Appl Microbiol, 103, 223-246
DOI 10.1016/bs.aambs.2018.01.003, PubMed 29914658

Simm R, Ahmad I, Rhen M, Le Guyon S, Römling U (2014)
Regulation of biofilm formation in Salmonella enterica serovar Typhimurium
Future Microbiol, 9 (11), 1261-82
DOI 10.2217/fmb.14.88, PubMed 25437188

Bergan J, Dyve Lingelem AB, Simm R, Skotland T, Sandvig K (2012)
Shiga toxins
Toxicon, 60 (6), 1085-107
DOI 10.1016/j.toxicon.2012.07.016, PubMed 22960449

Römling U, Simm R (2009)
Prevailing concepts of c-di-GMP signaling
Contrib Microbiol, 16, 161-181
DOI 10.1159/000219379, PubMed 19494585