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Publications by Ephrem Debebe Zegeye

17 publications found

Original articles

Zegeye ED, Aspholm M (2022)
Efficient Electrotransformation of Bacillus thuringiensis for Gene Manipulation and Expression
Curr Protoc, 2 (11), e588
DOI 10.1002/cpz1.588, PubMed 36350250

Zegeye ED, Diaz Y, Puntervoll P (2022)
Vaccine Candidate Double Mutant Variants of Enterotoxigenic Escherichia coli Heat-Stable Toxin
Vaccines (Basel), 10 (2)
DOI 10.3390/vaccines10020241, PubMed 35214698

Pradhan B, Liedtke J, Sleutel M, Lindbäck T, Zegeye ED, O Sullivan K, Llarena AK, Brynildsrud O, Aspholm M, Remaut H (2021)
Endospore Appendages: a novel pilus superfamily from the endospores of pathogenic Bacilli
EMBO J, 40 (17), e106887
DOI 10.15252/embj.2020106887, PubMed 34031903

Yimer SA, Kalayou S, Homberset H, Birhanu AG, Riaz T, Zegeye ED, Lutter T, Abebe M, Holm-Hansen C, Aseffa A, Tønjum T (2020)
Lineage-Specific Proteomic Signatures in the Mycobacterium tuberculosis Complex Reveal Differential Abundance of Proteins Involved in Virulence, DNA Repair, CRISPR-Cas, Bioenergetics and Lipid Metabolism
Front Microbiol, 11, 550760
DOI 10.3389/fmicb.2020.550760, PubMed 33072011

Diaz Y, Govasli ML, Zegeye ED, Sommerfelt H, Steinsland H, Puntervoll P (2019)
Immunizations with Enterotoxigenic Escherichia coli Heat-Stable Toxin Conjugates Engender Toxin-Neutralizing Antibodies in Mice That Also Cross-React with Guanylin and Uroguanylin
Infect Immun, 87 (7)
DOI 10.1128/IAI.00099-19, PubMed 31061144

Birhanu AG, Yimer SA, Kalayou S, Riaz T, Zegeye ED, Holm-Hansen C, Norheim G, Aseffa A, Abebe M, Tønjum T (2019)
Ample glycosylation in membrane and cell envelope proteins may explain the phenotypic diversity and virulence in the Mycobacterium tuberculosis complex
Sci Rep, 9 (1), 2927
DOI 10.1038/s41598-019-39654-9, PubMed 30814666

Govasli ML, Diaz Y, Zegeye ED, Darbakk C, Taxt AM, Puntervoll P (2018)
Purification and Characterization of Native and Vaccine Candidate Mutant Enterotoxigenic Escherichia coli Heat-Stable Toxins
Toxins (Basel), 10 (7)
DOI 10.3390/toxins10070274, PubMed 29970812

Yimer SA, Birhanu AG, Kalayou S, Riaz T, Zegeye ED, Beyene GT, Holm-Hansen C, Norheim G, Abebe M, Aseffa A, Tønjum T (2017)
Comparative Proteomic Analysis of Mycobacterium tuberculosis Lineage 7 and Lineage 4 Strains Reveals Differentially Abundant Proteins Linked to Slow Growth and Virulence
Front Microbiol, 8, 795
DOI 10.3389/fmicb.2017.00795, PubMed 28536560

Castañeda-García A, Prieto AI, Rodríguez-Beltrán J, Alonso N, Cantillon D, Costas C, Pérez-Lago L, Zegeye ED, Herranz M, Plociński P, Tonjum T, García de Viedma D, Paget M, Waddell SJ, Rojas AM, Doherty AJ, Blázquez J (2017)
A non-canonical mismatch repair pathway in prokaryotes
Nat Commun, 8, 14246
DOI 10.1038/ncomms14246, PubMed 28128207

Yimer SA, Namouchi A, Zegeye ED, Holm-Hansen C, Norheim G, Abebe M, Aseffa A, Tønjum T (2016)
Deciphering the recent phylogenetic expansion of the originally deeply rooted Mycobacterium tuberculosis lineage 7
BMC Evol Biol, 16 (1), 146
DOI 10.1186/s12862-016-0715-z, PubMed 27363525

Yimer SA, Norheim G, Namouchi A, Zegeye ED, Kinander W, Tønjum T, Bekele S, Mannsåker T, Bjune G, Aseffa A, Holm-Hansen C (2015)
Mycobacterium tuberculosis lineage 7 strains are associated with prolonged patient delay in seeking treatment for pulmonary tuberculosis in Amhara Region, Ethiopia
J Clin Microbiol, 53 (4), 1301-9
DOI 10.1128/JCM.03566-14, PubMed 25673798

Zegeye ED, Balasingham SV, Laerdahl JK, Homberset H, Kristiansen PE, Tønjum T (2013)
Effects of conserved residues and naturally occurring mutations on Mycobacterium tuberculosis RecG helicase activity
Microbiology (Reading), 160 (Pt 1), 217-227
DOI 10.1099/mic.0.072140-0, PubMed 24169816

Zegeye ED, Balasingham SV, Laerdahl JK, Homberset H, Tønjum T (2012)
Mycobacterium tuberculosis RecG binds and unwinds model DNA substrates with a preference for Holliday junctions
Microbiology (Reading), 158 (Pt 8), 1982-1993
DOI 10.1099/mic.0.058693-0, PubMed 22628485

Balasingham SV, Zegeye ED, Homberset H, Rossi ML, Laerdahl JK, Bohr VA, Tønjum T (2012)
Enzymatic activities and DNA substrate specificity of Mycobacterium tuberculosis DNA helicase XPB
PLoS One, 7 (5), e36960
DOI 10.1371/journal.pone.0036960, PubMed 22615856

Olsen I, Balasingham SV, Davidsen T, Debebe E, Rødland EA, van Soolingen D, Kremer K, Alseth I, Tønjum T (2009)
Characterization of the major formamidopyrimidine-DNA glycosylase homolog in Mycobacterium tuberculosis and its linkage to variable tandem repeats
FEMS Immunol Med Microbiol, 56 (2), 151-61
DOI 10.1111/j.1574-695X.2009.00562.x, PubMed 19496823

Review articles

Zegeye ED, Pradhan B, Llarena AK, Aspholm M (2021)
Enigmatic Pilus-Like Endospore Appendages of Bacillus cereus Group Species
Int J Mol Sci, 22 (22)
DOI 10.3390/ijms222212367, PubMed 34830248

Zegeye ED, Govasli ML, Sommerfelt H, Puntervoll P (2018)
Development of an enterotoxigenic Escherichia coli vaccine based on the heat-stable toxin
Hum Vaccin Immunother, 15 (6), 1379-1388
DOI 10.1080/21645515.2018.1496768, PubMed 30081709