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Publications by Jens Henrik Norum

18 publications found

Original articles

Połeć A, Ekstrøm PO, Fougner C, Sørlie T, Norum JH (2023)
Rapid assessment of 3-dimensional intra-tumor heterogeneity through cycling temperature capillary electrophoresis
BMC Res Notes, 16 (1), 167
DOI 10.1186/s13104-023-06437-5, PubMed 37568187

Oksvold MP, Berglund UW, Gad H, Bai B, Stokke T, Rein ID, Pham T, Sanjiv K, Øy GF, Norum JH, Smeland EB, Myklebust JH, Helleday T, Våtsveen TK (2021)
Karonudib has potent anti-tumor effects in preclinical models of B-cell lymphoma
Sci Rep, 11 (1), 6317
DOI 10.1038/s41598-021-85613-8, PubMed 33737576

Fougner C, Bergholtz H, Norum JH, Sørlie T (2020)
Re-definition of claudin-low as a breast cancer phenotype
Nat Commun, 11 (1), 1787
DOI 10.1038/s41467-020-15574-5, PubMed 32286297

Fougner C, Bergholtz H, Kuiper R, Norum JH, Sørlie T (2019)
Claudin-low-like mouse mammary tumors show distinct transcriptomic patterns uncoupled from genomic drivers
Breast Cancer Res, 21 (1), 85
DOI 10.1186/s13058-019-1170-8, PubMed 31366361

Norum JH, Frings O, Kasper M, Bergholtz H, Zell Thime H, Bergström Å, Andersson A, Kuiper R, Fredlund E, Sørlie T, Toftgård R (2019)
GLI1-induced mammary gland tumours are transplantable and maintain major molecular features
Int J Cancer, 146 (4), 1125-1138
DOI 10.1002/ijc.32522, PubMed 31219615

Norum JH, Skarpen E, Brech A, Kuiper R, Waaler J, Krauss S, Sørlie T (2018)
The tankyrase inhibitor G007-LK inhibits small intestine LGR5⁺ stem cell proliferation without altering tissue morphology
Biol Res, 51 (1), 3
DOI 10.1186/s40659-017-0151-6, PubMed 29316982

Norum JH, Bergström Å, Andersson AB, Kuiper RV, Hoelzl MA, Sørlie T, Toftgård R (2015)
A conditional transgenic mouse line for targeted expression of the stem cell marker LGR5
Dev Biol, 404 (2), 35-48
DOI 10.1016/j.ydbio.2015.05.002, PubMed 26003047

Goel HL, Gritsko T, Pursell B, Chang C, Shultz LD, Greiner DL, Norum JH, Toftgard R, Shaw LM, Mercurio AM (2014)
Regulated splicing of the α6 integrin cytoplasmic domain determines the fate of breast cancer stem cells
Cell Rep, 7 (3), 747-61
DOI 10.1016/j.celrep.2014.03.059, PubMed 24767994

Goel HL, Pursell B, Chang C, Shaw LM, Mao J, Simin K, Kumar P, Vander Kooi CW, Shultz LD, Greiner DL, Norum JH, Toftgard R, Kuperwasser C, Mercurio AM (2013)
GLI1 regulates a novel neuropilin-2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation
EMBO Mol Med, 5 (4), 488-508
DOI 10.1002/emmm.201202078, PubMed 23436775

Aesoy R, Sanchez BC, Norum JH, Lewensohn R, Viktorsson K, Linderholm B (2008)
An autocrine VEGF/VEGFR2 and p38 signaling loop confers resistance to 4-hydroxytamoxifen in MCF-7 breast cancer cells
Mol Cancer Res, 6 (10), 1630-8
DOI 10.1158/1541-7786.MCR-07-2172, PubMed 18922978

Norum JH, Dawood H, Mattingly RR, Sandnes D, Levy FO (2006)
Epac- and Rap- independent ERK1/2 phosphorylation induced by Gs-coupled receptor stimulation in HEK293 cells
FEBS Lett, 581 (1), 15-20
DOI 10.1016/j.febslet.2006.11.069, PubMed 17174312

Andressen KW, Norum JH, Levy FO, Krobert KA (2005)
Activation of adenylyl cyclase by endogenous G(s)-coupled receptors in human embryonic kidney 293 cells is attenuated by 5-HT(7) receptor expression
Mol Pharmacol, 69 (1), 207-15
DOI 10.1124/mol.105.015396, PubMed 16189297

Norum JH, Méthi T, Mattingly RR, Levy FO (2005)
Endogenous expression and protein kinase A-dependent phosphorylation of the guanine nucleotide exchange factor Ras-GRF1 in human embryonic kidney 293 cells
FEBS J, 272 (9), 2304-16
DOI 10.1111/j.1742-4658.2005.04658.x, PubMed 15853814

Norum JH, Hart K, Levy FO (2002)
Ras-dependent ERK activation by the human G(s)-coupled serotonin receptors 5-HT4(b) and 5-HT7(a)
J Biol Chem, 278 (5), 3098-104
DOI 10.1074/jbc.M206237200, PubMed 12446729

Ostvold AC, Norum JH, Mathiesen S, Wanvik B, Sefland I, Grundt K (2001)
Molecular cloning of a mammalian nuclear phosphoprotein NUCKS, which serves as a substrate for Cdk1 in vivo
Eur J Biochem, 268 (8), 2430-40
DOI 10.1046/j.1432-1327.2001.02120.x, PubMed 11298763

Review articles

Byrne AT, Alférez DG, Amant F, Annibali D, Arribas J, Biankin AV, Bruna A, Budinská E, Caldas C, Chang DK, Clarke RB, Clevers H, Coukos G, Dangles-Marie V, Eckhardt SG, Gonzalez-Suarez E, Hermans E, Hidalgo M, Jarzabek MA, de Jong S, Jonkers J, Kemper K, Lanfrancone L, Mælandsmo GM, Marangoni E et al. (2017)
Interrogating open issues in cancer precision medicine with patient-derived xenografts
Nat Rev Cancer, 17 (4), 254-268
DOI 10.1038/nrc.2016.140, PubMed 28104906

Norum JH, Andersen K, Sørlie T (2014)
Lessons learned from the intrinsic subtypes of breast cancer in the quest for precision therapy
Br J Surg, 101 (8), 925-38
DOI 10.1002/bjs.9562, PubMed 24849143

Other articles

Byrne AT, Alférez DG, Amant F, Annibali D, Arribas J, Biankin AV, Bruna A, Budinská E, Caldas C, Chang DK, Clarke RB, Clevers H, Coukos G, Dangles-Marie V, Eckhardt SG, Gonzalez-Suarez E, Hermans E, Hidalgo M, Jarzabek MA, de Jong S, Jonkers J, Kemper K, Lanfrancone L, Mælandsmo GM, Marangoni E et al. (2017)
Interrogating open issues in cancer medicine with patient-derived xenografts
Nat Rev Cancer, 17 (10), 632 (in press)
DOI 10.1038/nrc.2017.85, PubMed 28912576