Publications by Terhi Kärpänen
27 publications found
Original articles
A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo
Nat Cancer, 4 (10), 1474-1490
DOI 10.1038/s43018-023-00642-8, PubMed 37783807
Efficient activation of the lymphangiogenic growth factor VEGF-C requires the C-terminal domain of VEGF-C and the N-terminal domain of CCBE1
Sci Rep, 7 (1), 4916
DOI 10.1038/s41598-017-04982-1, PubMed 28687807
An Evolutionarily Conserved Role for Polydom/Svep1 During Lymphatic Vessel Formation
Circ Res, 120 (8), 1263-1275
DOI 10.1161/CIRCRESAHA.116.308813, PubMed 28179432
The zebrafish common cardinal veins develop by a novel mechanism: lumen ensheathment
Development, 140 (13), 2776-86
DOI 10.1242/dev.091876, PubMed 23698350
CCBE1 is essential for mammalian lymphatic vascular development and enhances the lymphangiogenic effect of vascular endothelial growth factor-C in vivo
Circ Res, 109 (5), 486-91
DOI 10.1161/CIRCRESAHA.111.250738, PubMed 21778431
Notch restricts lymphatic vessel sprouting induced by vascular endothelial growth factor
Blood, 118 (4), 1154-62
DOI 10.1182/blood-2010-11-317800, PubMed 21566091
Zebrafish provides a novel model for lymphatic vascular research
Methods Cell Biol, 105, 223-38
DOI 10.1016/B978-0-12-381320-6.00009-6, PubMed 21951532
miR-31 functions as a negative regulator of lymphatic vascular lineage-specific differentiation in vitro and vascular development in vivo
Mol Cell Biol, 30 (14), 3620-34
DOI 10.1128/MCB.00185-10, PubMed 20479124
Targeting lymphatic vessel activation and CCL21 production by vascular endothelial growth factor receptor-3 inhibition has novel immunomodulatory and antiarteriosclerotic effects in cardiac allografts
Circulation, 121 (12), 1413-22
DOI 10.1161/CIRCULATIONAHA.109.910703, PubMed 20231530
Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy
Circ Res, 103 (9), 1018-26
DOI 10.1161/CIRCRESAHA.108.178459, PubMed 18757827
Enhanced capillary formation stimulated by a chimeric vascular endothelial growth factor/vascular endothelial growth factor-C silk domain fusion protein
Circ Res, 100 (10), 1460-7
DOI 10.1161/01.RES.0000269042.58594.f6, PubMed 17478734
Lymphangiogenic growth factor responsiveness is modulated by postnatal lymphatic vessel maturation
Am J Pathol, 169 (2), 708-18
DOI 10.2353/ajpath.2006.051200, PubMed 16877368
Functional interaction of VEGF-C and VEGF-D with neuropilin receptors
FASEB J, 20 (9), 1462-72
DOI 10.1096/fj.05-5646com, PubMed 16816121
Vascular endothelial growth factor (VEGF)/VEGF-C mosaic molecules reveal specificity determinants and feature novel receptor binding patterns
J Biol Chem, 281 (17), 12187-95
DOI 10.1074/jbc.M511593200, PubMed 16505489
Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis
Nat Med, 10 (9), 974-81
DOI 10.1038/nm1094, PubMed 15322537
PDGF-D induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis
Blood, 104 (10), 3198-204
DOI 10.1182/blood-2004-04-1485, PubMed 15271796
Antitumor activity of a homing peptide that targets tumor lymphatics and tumor cells
Proc Natl Acad Sci U S A, 101 (25), 9381-6
DOI 10.1073/pnas.0403317101, PubMed 15197262
Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling
J Natl Cancer Inst, 94 (11), 819-25
DOI 10.1093/jnci/94.11.819, PubMed 12048269
VEGF-C induced lymphangiogenesis is associated with lymph node metastasis in orthotopic MCF-7 tumors
Int J Cancer, 98 (6), 946-51
DOI 10.1002/ijc.10283, PubMed 11948478
Vascular endothelial growth factor ligands and receptors that regulate human cytotrophoblast survival are dysregulated in severe preeclampsia and hemolysis, elevated liver enzymes, and low platelets syndrome
Am J Pathol, 160 (4), 1405-23
DOI 10.1016/S0002-9440(10)62567-9, PubMed 11943725
Review articles
A Literature Review on Cognitive Accessibility
Stud Health Technol Inform, 282, 259-270
DOI 10.3233/SHTI210402, PubMed 34085974
The Potential of Donor T-Cell Repertoires in Neoantigen-Targeted Cancer Immunotherapy
Front Immunol, 8, 1718
DOI 10.3389/fimmu.2017.01718, PubMed 29321773
T-cell receptor gene therapy--ready to go viral?
Mol Oncol, 9 (10), 2019-42
DOI 10.1016/j.molonc.2015.10.006, PubMed 26548533
Molecular biology and pathology of lymphangiogenesis
Annu Rev Pathol, 3, 367-97
DOI 10.1146/annurev.pathmechdis.3.121806.151515, PubMed 18039141
Regulation of lymphangiogenesis--from cell fate determination to vessel remodeling
Exp Cell Res, 312 (5), 575-83
DOI 10.1016/j.yexcr.2005.10.034, PubMed 16343484
Role of lymphangiogenic factors in tumor metastasis
Biochim Biophys Acta, 1654 (1), 3-12
DOI 10.1016/j.bbcan.2003.07.003, PubMed 14984763
Other articles
VEGF-D: a modifier of embryonic lymphangiogenesis
Blood, 112 (5), 1547-8
DOI 10.1182/blood-2008-06-159343, PubMed 18725566