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Publications by Iris Bigalke

13 publications found

Original articles

Maggadottir SM, Dueland S, Mensali N, Hamre H, Andresen PA, Myhre MR, Juul HV, Bigalke I, Lundby M, Hønnåshagen TK, Sæbøe-Larssen S, Josefsen D, Hagtvedt T, Wälchli S, Kvalheim G, Inderberg EM (2024)
Transient TCR-based T cell therapy in a patient with advanced treatment-resistant MSI-high colorectal cancer
Mol Ther (in press)
DOI 10.1016/j.ymthe.2024.04.009, PubMed 38582964

Fløisand Y, Remberger M, Bigalke I, Josefsen D, Vålerhaugen H, Inderberg EM, Olaussen RW, Gjertsen BT, Goedkoop R, Geiger C, Prinz PU, Schnorfeil FM, Pinkernell K, Schendel DJ, Kvalheim G (2023)
WT1 and PRAME RNA-loaded dendritic cell vaccine as maintenance therapy in de novo AML after intensive induction chemotherapy
Leukemia, 37 (9), 1842-1849
DOI 10.1038/s41375-023-01980-3, PubMed 37507426

Thomsen LCV, Honoré A, Reisæter LAR, Almås B, Børretzen A, Helle SI, Førde K, Kristoffersen EK, Kaada SH, Melve GK, Haslerud TM, Biermann M, Bigalke I, Kvalheim G, Azeem W, Olsen JR, Gabriel B, Knappskog S, Halvorsen OJ, Akslen LA, Bahn D, Pantel K, Riethdorf S, Ragde H, Gjertsen BT et al. (2023)
A phase I prospective, non-randomized trial of autologous dendritic cell-based cryoimmunotherapy in patients with metastatic castration-resistant prostate cancer
Cancer Immunol Immunother, 72 (7), 2357-2373
DOI 10.1007/s00262-023-03421-7, PubMed 36939854

Tryggestad AMA, Axcrona K, Axcrona U, Bigalke I, Brennhovd B, Inderberg EM, Hønnåshagen TK, Skoge LJ, Solum G, Saebøe-Larssen S, Josefsen D, Olaussen RW, Aamdal S, Skotheim RI, Myklebust TÅ, Schendel DJ, Lilleby W, Dueland S, Kvalheim G (2021)
Long-term first-in-man Phase I/II study of an adjuvant dendritic cell vaccine in patients with high-risk prostate cancer after radical prostatectomy
Prostate, 82 (2), 245-253
DOI 10.1002/pros.24267, PubMed 34762317

Lichtenegger FS, Schnorfeil FM, Rothe M, Deiser K, Altmann T, Bücklein VL, Köhnke T, Augsberger C, Konstandin NP, Spiekermann K, Moosmann A, Boehm S, Boxberg M, Heemskerk MH, Goerlich D, Wittmann G, Wagner B, Hiddemann W, Schendel DJ, Kvalheim G, Bigalke I, Subklewe M (2020)
Toll-like receptor 7/8-matured RNA-transduced dendritic cells as post-remission therapy in acute myeloid leukaemia: results of a phase I trial
Clin Transl Immunology, 9 (3), e1117
DOI 10.1002/cti2.1117, PubMed 32153780

Kolb HJ, Schmetzer H, Schmid C, Bigalke I, Buhmann R, Moosmann A, Falk C, Reuther S, Schuster F, Borkhardt A (2014)
Mechanisms of graft-versus-leukemia effects after allogeneic stem cell transplantation: effects on the leukemia stem cell?
Leuk Suppl, 3 (Suppl 1), S16-7
DOI 10.1038/leusup.2014.9, PubMed 27175264

Spranger S, Javorovic M, Bürdek M, Wilde S, Mosetter B, Tippmer S, Bigalke I, Geiger C, Schendel DJ, Frankenberger B (2010)
Generation of Th1-polarizing dendritic cells using the TLR7/8 agonist CL075
J Immunol, 185 (1), 738-47
DOI 10.4049/jimmunol.1000060, PubMed 20511554

Moosmann A, Bigalke I, Tischer J, Schirrmann L, Kasten J, Tippmer S, Leeping M, Prevalsek D, Jaeger G, Ledderose G, Mautner J, Hammerschmidt W, Schendel DJ, Kolb HJ (2010)
Effective and long-term control of EBV PTLD after transfer of peptide-selected T cells
Blood, 115 (14), 2960-70
DOI 10.1182/blood-2009-08-236356, PubMed 20103780

Zobywalski A, Javorovic M, Frankenberger B, Pohla H, Kremmer E, Bigalke I, Schendel DJ (2007)
Generation of clinical grade dendritic cells with capacity to produce biologically active IL-12p70
J Transl Med, 5, 18
DOI 10.1186/1479-5876-5-18, PubMed 17430585

Offner FA, Schiefer J, Wirtz HC, Bigalke I, Pavelka M, Hollweg G, Ensinger C, Klosterhalfen B, Mittermayer C, Kirkpatrick CJ (1996)
Tumour-cell-endothelial interactions: free radicals are mediators of melanoma-induced endothelial cell damage
Virchows Arch, 428 (2), 99-106
DOI 10.1007/BF00193937, PubMed 8925131

Offner FA, Bigalke I, Schiefer J, Wirtz HC, Klosterhalfen B, Feichtinger H, Kirkpatrick CJ (1993)
Interaction of human malignant melanoma tumor spheroids with endothelium and reconstituted basement membrane: modulation by RGDS
Int J Cancer, 54 (3), 506-12
DOI 10.1002/ijc.2910540325, PubMed 8509226

Offner FA, Wirtz HC, Schiefer J, Bigalke I, Klosterhalfen B, Bittinger F, Mittermayer C, Kirkpatrick CJ (1992)
Interaction of human malignant melanoma (ST-ML-12) tumor spheroids with endothelial cell monolayers. Damage to endothelium by oxygen-derived free radicals
Am J Pathol, 141 (3), 601-10
PubMed 1519667

Review articles

Subklewe M, Geiger C, Lichtenegger FS, Javorovic M, Kvalheim G, Schendel DJ, Bigalke I (2014)
New generation dendritic cell vaccine for immunotherapy of acute myeloid leukemia
Cancer Immunol Immunother, 63 (10), 1093-103
DOI 10.1007/s00262-014-1600-5, PubMed 25186611