Publications by Synne Jenum
35 publications found
Original articles
The Cyclooxygenase 2 Inhibitor Etoricoxib as Adjunctive Therapy in Tuberculosis Impairs Macrophage Control of Mycobacterial Growth
J Infect Dis, 229 (3), 888-897
DOI 10.1093/infdis/jiad390, PubMed 37721470
Whole blood RNA signatures in tuberculosis patients receiving H56:IC31 vaccine as adjunctive therapy
Front Immunol, 15, 1350593
DOI 10.3389/fimmu.2024.1350593, PubMed 38433842
The diagnostic utility of microscopic quality assessment of sputum samples in the era of rapid syndromic PCR testing
Microbiol Spectr, 11 (5), e0300223 (in press)
DOI 10.1128/spectrum.03002-23, PubMed 37772853
Gut microbiota composition during hospitalization is associated with 60-day mortality after severe COVID-19
Crit Care, 27 (1), 69
DOI 10.1186/s13054-023-04356-2, PubMed 36814280
Host blood-based biosignatures for subclinical TB and incipient TB: A prospective study of adult TB household contacts in Southern India
Front Immunol, 13, 1051963
DOI 10.3389/fimmu.2022.1051963, PubMed 36713386
Host Transcriptional Signatures Predict Etiology in Community-Acquired Pneumonia: Potential Antibiotic Stewardship Tools
Biomark Insights, 17, 11772719221099130
DOI 10.1177/11772719221099130, PubMed 35693251
Improving Assignments for Therapeutic and Prophylactic Treatment Within TB Households. A Potential for Immuno-Diagnosis?
Front Immunol, 13, 801616
DOI 10.3389/fimmu.2022.801616, PubMed 35401549
A Phase I/II randomized trial of H56:IC31 vaccination and adjunctive cyclooxygenase-2-inhibitor treatment in tuberculosis patients
Nat Commun, 12 (1), 6774
DOI 10.1038/s41467-021-27029-6, PubMed 34811370
CCL1 and IL-2Ra differentiate Tuberculosis disease from latent infection Irrespective of HIV infection in low TB burden countries
J Infect, 83 (4), 433-443
DOI 10.1016/j.jinf.2021.07.036, PubMed 34333033
Plasma LOX-Products and Monocyte Signaling Is Reduced by Adjunctive Cyclooxygenase-2 Inhibitor in a Phase I Clinical Trial of Tuberculosis Patients
Front Cell Infect Microbiol, 11, 669623
DOI 10.3389/fcimb.2021.669623, PubMed 34307194
A 2-Dose AERAS-402 Regimen Boosts CD8+ Polyfunctionality in HIV-Negative, BCG-Vaccinated Recipients
Front Immunol, 12, 673532
DOI 10.3389/fimmu.2021.673532, PubMed 34177914
Critical COVID-19 is associated with distinct leukocyte phenotypes and transcriptome patterns
J Intern Med, 290 (3), 677-692
DOI 10.1111/joim.13310, PubMed 34080738
A Plasma 5-Marker Host Biosignature Identifies Tuberculosis in High and Low Endemic Countries
Front Immunol, 12, 608846
DOI 10.3389/fimmu.2021.608846, PubMed 33732236
Host Blood RNA Transcript and Protein Signatures for Sputum-Independent Diagnostics of Tuberculosis in Adults
Front Immunol, 11, 626049
DOI 10.3389/fimmu.2020.626049, PubMed 33613569
Increased interleukin-6 and macrophage chemoattractant protein-1 are associated with respiratory failure in COVID-19
Sci Rep, 10 (1), 21697
DOI 10.1038/s41598-020-78710-7, PubMed 33303843
Elevated Levels of Anti-Inflammatory Eicosanoids and Monocyte Heterogeneity in Mycobacterium tuberculosis Infection and Disease
Front Immunol, 11, 579849
DOI 10.3389/fimmu.2020.579849, PubMed 33304347
Monocytic myeloid-derived suppressor cells reflect tuberculosis severity and are influenced by cyclooxygenase-2 inhibitors
J Leukoc Biol, 110 (1), 177-186
DOI 10.1002/JLB.4A0720-409RR, PubMed 33155730
Elevated plasma sTIM-3 levels in patients with severe COVID-19
J Allergy Clin Immunol, 147 (1), 92-98
DOI 10.1016/j.jaci.2020.09.007, PubMed 32971109
Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients
Proc Natl Acad Sci U S A, 117 (40), 25018-25025
DOI 10.1073/pnas.2010540117, PubMed 32943538
Combining host-derived biomarkers with patient characteristics improves signature performance in predicting tuberculosis treatment outcomes
Commun Biol, 3 (1), 359
DOI 10.1038/s42003-020-1087-x, PubMed 32647325
Identification of subclinical tuberculosis in household contacts using exposure scores and contact investigations
BMC Infect Dis, 20 (1), 96
DOI 10.1186/s12879-020-4800-y, PubMed 32005136
Cyclooxygenase inhibitors impair CD4 T cell immunity and exacerbate Mycobacterium tuberculosis infection in aerosol-challenged mice
Commun Biol, 2, 288
DOI 10.1038/s42003-019-0530-3, PubMed 31396568
Incidence of tuberculosis and the influence of surveillance strategy on tuberculosis case-finding and all-cause mortality: a cluster randomised trial in Indian neonates vaccinated with BCG
BMJ Open Respir Res, 5 (1), e000304
DOI 10.1136/bmjresp-2018-000304, PubMed 30397482
Clinical and bacteriological efficacy of pivmecillinam treatment for uncomplicated urinary tract infections caused by ESBL-producing Escherichia coli: a prospective, multicentre, observational cohort study
J Antimicrob Chemother, 73 (9), 2503-2509
DOI 10.1093/jac/dky230, PubMed 29982514
Novel transcriptional signatures for sputum-independent diagnostics of tuberculosis in children
Sci Rep, 7 (1), 5839
DOI 10.1038/s41598-017-05057-x, PubMed 28724962
BLR1 and FCGR1A transcripts in peripheral blood associate with the extent of intrathoracic tuberculosis in children and predict treatment outcome
Sci Rep, 6, 38841
DOI 10.1038/srep38841, PubMed 27941850
Added Value of IP-10 as a Read-Out of Mycobacterium tuberculosis: Specific Immunity in Young Children
Pediatr Infect Dis J, 35 (12), 1336-1338
DOI 10.1097/INF.0000000000001328, PubMed 27642776
Approaching a diagnostic point-of-care test for pediatric tuberculosis through evaluation of immune biomarkers across the clinical disease spectrum
Sci Rep, 6, 18520
DOI 10.1038/srep18520, PubMed 26725873
Effect of non-tuberculous Mycobacteria on host biomarkers potentially relevant for tuberculosis management
PLoS Negl Trop Dis, 8 (10), e3243
DOI 10.1371/journal.pntd.0003243, PubMed 25329719
Influence of age and nutritional status on the performance of the tuberculin skin test and QuantiFERON-TB gold in-tube in young children evaluated for tuberculosis in Southern India
Pediatr Infect Dis J, 33 (10), e260-9
DOI 10.1097/INF.0000000000000399, PubMed 24797993
The frequencies of IFNγ+IL2+TNFα+ PPD-specific CD4+CD45RO+ T-cells correlate with the magnitude of the QuantiFERON® gold in-tube response in a prospective study of healthy indian adolescents
PLoS One, 9 (7), e101224
DOI 10.1371/journal.pone.0101224, PubMed 24992314
Concordant or discordant results by the tuberculin skin test and the quantiFERON-TB test in children reflect immune biomarker profiles
Genes Immun, 15 (5), 265-74
DOI 10.1038/gene.2014.13, PubMed 24739497
Identification of biomarkers for Mycobacterium tuberculosis infection and disease in BCG-vaccinated young children in Southern India
Genes Immun, 14 (6), 356-64
DOI 10.1038/gene.2013.26, PubMed 23676757
Other articles
A man in his seventies with pleural effusion, knee pain and dysarthria following open heart surgery
Tidsskr Nor Laegeforen, 141 (18)
DOI 10.4045/tidsskr.21.0163, PubMed 34911264
KLRG1-Expressing CD4 T Cells Are Reduced in Tuberculosis Patients Compared to Healthy Mycobacterium tuberculosis-Infected Subjects, but Increase With Treatment
J Infect Dis, 220 (1), 174-176
DOI 10.1093/infdis/jiz056, PubMed 30888024