Publications by Ida Gjervold Lunde
66 publications found
Original articles
Acute heart failure: mechanisms and pre-clinical models-a Scientific Statement of the ESC Working Group on Myocardial Function
Cardiovasc Res, 119 (14), 2390-2404
DOI 10.1093/cvr/cvad088, PubMed 37967390
Temporal expression and spatial distribution of the proteoglycan versican during cardiac fibrosis development
Matrix Biol Plus, 19-20, 100135
DOI 10.1016/j.mbplus.2023.100135, PubMed 38076279
Inhibition of the extracellular enzyme A disintegrin and metalloprotease with thrombospondin motif 4 prevents cardiac fibrosis and dysfunction
Cardiovasc Res, 119 (10), 1915-1927
DOI 10.1093/cvr/cvad078, PubMed 37216909
Stretch Harmonizes Sarcomere Strain Across the Cardiomyocyte
Circ Res, 133 (3), 255-270
DOI 10.1161/CIRCRESAHA.123.322588, PubMed 37401464
Beneficial effects of exercise initiated before development of hypertrophic cardiomyopathy in genotype-positive mice
Am J Physiol Heart Circ Physiol, 324 (6), H881-H892
DOI 10.1152/ajpheart.00701.2022, PubMed 37115627
Inflammation and Syndecan-4 Shedding from Cardiac Cells in Ischemic and Non-Ischemic Heart Disease
Biomedicines, 11 (4)
DOI 10.3390/biomedicines11041066, PubMed 37189684
Prevalence and Clinical Consequences of Multiple Pathogenic Variants in Dilated Cardiomyopathy
Circ Genom Precis Med, 16 (2), e003788
DOI 10.1161/CIRCGEN.122.003788, PubMed 36971006
ADAMTSL3 knock-out mice develop cardiac dysfunction and dilatation with increased TGFβ signalling after pressure overload
Commun Biol, 5 (1), 1392
DOI 10.1038/s42003-022-04361-1, PubMed 36539599
Lumican accumulates with fibrillar collagen in fibrosis in hypertrophic cardiomyopathy
ESC Heart Fail, 10 (2), 858-871
DOI 10.1002/ehf2.14234, PubMed 36444917
Calcineurin-NFAT dynamics correspond to cardiac remodeling during aortic banding and debanding, mimicking aortic valve replacement
Front Mol Med, 2, 1-14
DOI 10.3389/fmmed.2022.980717, PublikaID 435
Cardiomyocyte-specific overexpression of syndecan-4 in mice results in activation of calcineurin-NFAT signalling and exacerbated cardiac hypertrophy
Mol Biol Rep, 49 (12), 11795-11809
DOI 10.1007/s11033-022-07985-y, PubMed 36205855
Exercise training during childhood and adolescence is associated with favorable diastolic function in hypertrophic cardiomyopathy
Int J Cardiol, 364, 65-71
DOI 10.1016/j.ijcard.2022.06.042, PubMed 35714718
Integrin α11β1 and syndecan-4 dual receptor ablation attenuate cardiac hypertrophy in the pressure overloaded heart
Am J Physiol Heart Circ Physiol, 322 (6), H1057-H1071
DOI 10.1152/ajpheart.00635.2021, PubMed 35522553
The small leucine-rich proteoglycan fibromodulin exerts anti-fibrotic effects in cultured human cardiac fibroblasts
Genet Mol Res, 21 (1), 1-15
DOI 10.4238/gmr19007, PublikaID 434
Atrial disease and heart failure: the common soil hypothesis proposed by the Heart Failure Association of the European Society of Cardiology
Eur Heart J (in press)
DOI 10.1093/eurheartj/ehab834, PubMed 34875053
The extracellular matrix glycoprotein ADAMTSL2 is increased in heart failure and inhibits TGFβ signalling in cardiac fibroblasts
Sci Rep, 11 (1), 19757
DOI 10.1038/s41598-021-99032-2, PubMed 34611183
Etiology-Dependent Impairment of Diastolic Cardiomyocyte Calcium Homeostasis in Heart Failure With Preserved Ejection Fraction
J Am Coll Cardiol, 77 (4), 405-419
DOI 10.1016/j.jacc.2020.11.044, PubMed 33509397
Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin
J Am Heart Assoc, 9 (3), e013518
DOI 10.1161/JAHA.119.013518, PubMed 32000579
Moderate Loss of the Extracellular Matrix Proteoglycan Lumican Attenuates Cardiac Fibrosis in Mice Subjected to Pressure Overload
Cardiology, 145 (3), 187-198
DOI 10.1159/000505318, PubMed 31968347
Yin Yang 1 Suppresses Dilated Cardiomyopathy and Cardiac Fibrosis Through Regulation of Bmp7 and Ctgf
Circ Res, 125 (9), 834-846
DOI 10.1161/CIRCRESAHA.119.314794, PubMed 31495264
Increased Complement Factor B and Bb Levels Are Associated with Mortality in Patients with Severe Aortic Stenosis
J Immunol, 203 (7), 1973-1980
DOI 10.4049/jimmunol.1801244, PubMed 31492744
The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload
Sci Rep, 9 (1), 9206
DOI 10.1038/s41598-019-45651-9, PubMed 31235849
Genetic Variants Associated With Cancer Therapy-Induced Cardiomyopathy
Circulation, 140 (1), 31-41
DOI 10.1161/CIRCULATIONAHA.118.037934, PubMed 30987448
Secretoneurin Is an Endogenous Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor That Attenuates Ca2+-Dependent Arrhythmia
Circ Arrhythm Electrophysiol, 12 (4), e007045
DOI 10.1161/CIRCEP.118.007045, PubMed 30943765
Towards better definition, quantification and treatment of fibrosis in heart failure. A scientific roadmap by the Committee of Translational Research of the Heart Failure Association (HFA) of the European Society of Cardiology
Eur J Heart Fail, 21 (3), 272-285
DOI 10.1002/ejhf.1406, PubMed 30714667
Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin
Sci Transl Med, 11 (476)
DOI 10.1126/scitranslmed.aat1199, PubMed 30674652
Trifecta has lower gradient and less prosthesis-patient mismatch than Mosaic Ultra in the aortic position: A prospective randomized study
J Thorac Cardiovasc Surg, 158 (4), 1032-1039
DOI 10.1016/j.jtcvs.2018.11.020, PubMed 30635187
Myocardial Fibrosis
Tidsskr. Nor. Laegeforen., 138 (16), 1533-1539
A novel method for high precision aortic constriction that allows for generation of specific cardiac phenotypes in mice
Cardiovasc Res, 114 (12), 1680-1690
DOI 10.1093/cvr/cvy141, PubMed 29878127
The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling
PLoS One, 13 (7), e0201422
DOI 10.1371/journal.pone.0201422, PubMed 30052659
Sweet, yet underappreciated: Proteoglycans and extracellular matrix remodeling in heart disease
Matrix Biol, 75-76, 286-299
DOI 10.1016/j.matbio.2018.01.001, PubMed 29337052
The autonomic nervous system as a therapeutic target in heart failure: a scientific position statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology
Eur J Heart Fail, 19 (11), 1361-1378
DOI 10.1002/ejhf.921, PubMed 28949064
Wnt5a is associated with right ventricular dysfunction and adverse outcome in dilated cardiomyopathy
Sci Rep, 7 (1), 3490
DOI 10.1038/s41598-017-03625-9, PubMed 28615692
Bigger is not better: cortisol-induced cardiac growth and dysfunction in salmonids
J Exp Biol, 220 (Pt 14), 2545-2553
DOI 10.1242/jeb.135046, PubMed 28476893
The Notch Ligands DLL1 and Periostin Are Associated with Symptom Severity and Diastolic Function in Dilated Cardiomyopathy
J Cardiovasc Transl Res, 10 (4), 401-410
DOI 10.1007/s12265-017-9748-y, PubMed 28474304
Wnt5a is elevated in heart failure and affects cardiac fibroblast function
J Mol Med (Berl), 95 (7), 767-777
DOI 10.1007/s00109-017-1529-1, PubMed 28357477
The Heparan Sulfate Proteoglycan Glypican-6 Is Upregulated in the Failing Heart, and Regulates Cardiomyocyte Growth through ERK1/2 Signaling
PLoS One, 11 (10), e0165079
DOI 10.1371/journal.pone.0165079, PubMed 27768722
Exercise training increases protein O-GlcNAcylation in rat skeletal muscle
Physiol Rep, 4 (18)
DOI 10.14814/phy2.12896, PubMed 27664189
Increased hypertrophic response with increased mechanical load in skeletal muscles receiving identical activity patterns
Am J Physiol Cell Physiol, 311 (4), C616-C629
DOI 10.1152/ajpcell.00016.2016, PubMed 27488660
Shedding of syndecan-4 promotes immune cell recruitment and mitigates cardiac dysfunction after lipopolysaccharide challenge in mice
J Mol Cell Cardiol, 88, 133-44
DOI 10.1016/j.yjmcc.2015.10.003, PubMed 26449522
Absence of the inflammasome adaptor ASC reduces hypoxia-induced pulmonary hypertension in mice
Am J Physiol Lung Cell Mol Physiol, 309 (4), L378-87
DOI 10.1152/ajplung.00342.2014, PubMed 26071556
Lack of collagen VIII reduces fibrosis and promotes early mortality and cardiac dilatation in pressure overload in mice
Cardiovasc Res, 106 (1), 32-42
DOI 10.1093/cvr/cvv041, PubMed 25694587
Exhausting treadmill running causes dephosphorylation of sMLC2 and reduced level of myofilament MLCK2 in slow twitch rat soleus muscle
Physiol Rep, 3 (2)
DOI 10.14814/phy2.12285, PubMed 25713325
Syndecan-4 is a key determinant of collagen cross-linking and passive myocardial stiffness in the pressure-overloaded heart
Cardiovasc Res, 106 (2), 217-26
DOI 10.1093/cvr/cvv002, PubMed 25587045
Molecular basis of calpain cleavage and inactivation of the sodium-calcium exchanger 1 in heart failure
J Biol Chem, 289 (49), 33984-98
DOI 10.1074/jbc.M114.602581, PubMed 25336645
Pentosan polysulfate decreases myocardial expression of the extracellular matrix enzyme ADAMTS4 and improves cardiac function in vivo in rats subjected to pressure overload by aortic banding
PLoS One, 9 (3), e89621
DOI 10.1371/journal.pone.0089621, PubMed 24595230
Lumican is increased in experimental and clinical heart failure, and its production by cardiac fibroblasts is induced by mechanical and proinflammatory stimuli
FEBS J, 280 (10), 2382-98
DOI 10.1111/febs.12235, PubMed 23480731
Innate immune signaling induces expression and shedding of the heparan sulfate proteoglycan syndecan-4 in cardiac fibroblasts and myocytes, affecting inflammation in the pressure-overloaded heart
FEBS J, 280 (10), 2228-47
DOI 10.1111/febs.12161, PubMed 23374111
Syndecan-4 signaling via NFAT regulates extracellular matrix production and cardiac myofibroblast differentiation in response to mechanical stress
J Mol Cell Cardiol, 54, 73-81
DOI 10.1016/j.yjmcc.2012.11.006, PubMed 23178899
Chemokines regulate small leucine-rich proteoglycans in the extracellular matrix of the pressure-overloaded right ventricle
J Appl Physiol (1985), 112 (8), 1372-82
DOI 10.1152/japplphysiol.01350.2011, PubMed 22345433
Endothelin-1 in the human myocardium and circulating plasma: evaluation before, during and after correction of aortic stenosis with aortic valve replacement
Cardiology, 123 (1), 1-10
DOI 10.1159/000339756, PubMed 22907118
Cardiac O-GlcNAc signaling is increased in hypertrophy and heart failure
Physiol Genomics, 44 (2), 162-72
DOI 10.1152/physiolgenomics.00016.2011, PubMed 22128088
Cortisol response to stress is associated with myocardial remodeling in salmonid fishes
J Exp Biol, 214 (Pt 8), 1313-21
DOI 10.1242/jeb.053058, PubMed 21430209
Angiotensin II and norepinephrine activate specific calcineurin-dependent NFAT transcription factor isoforms in cardiomyocytes
J Appl Physiol (1985), 111 (5), 1278-89
DOI 10.1152/japplphysiol.01383.2010, PubMed 21474694
Hypoxia inducible factor 1 links fast-patterned muscle activity and fast muscle phenotype in rats
J Physiol, 589 (Pt 6), 1443-54
DOI 10.1113/jphysiol.2010.202762, PubMed 21262877
Syndecan-4 is essential for development of concentric myocardial hypertrophy via stretch-induced activation of the calcineurin-NFAT pathway
PLoS One, 6 (12), e28302
DOI 10.1371/journal.pone.0028302, PubMed 22164265
Trophic structure and community stability in an overfished ecosystem
Science, 329 (5989), 333-6
DOI 10.1126/science.1190708, PubMed 20647468
Elevated temperature reduces the respiratory scope of coral reef fishes
Glob. Change Biol., 15 (6), 1405-1412
DOI 10.1111/j.1365-2486.2008.01767.x
PPARdelta expression is influenced by muscle activity and induces slow muscle properties in adult rat muscles after somatic gene transfer
J Physiol, 582 (Pt 3), 1277-87
DOI 10.1113/jphysiol.2007.133025, PubMed 17463039
Review articles
Emerging roles for the ADAMTS-like family of matricellular proteins in cardiovascular disease through regulation of the extracellular microenvironment
Mol Biol Rep, 51 (1), 280
DOI 10.1007/s11033-024-09255-5, PubMed 38324186
The continuous heart failure spectrum: moving beyond an ejection fraction classification
Eur Heart J, 40 (26), 2155-2163
DOI 10.1093/eurheartj/ehz158, PubMed 30957868
Heart failure and diabetes: metabolic alterations and therapeutic interventions: a state-of-the-art review from the Translational Research Committee of the Heart Failure Association-European Society of Cardiology
Eur Heart J, 39 (48), 4243-4254
DOI 10.1093/eurheartj/ehy596, PubMed 30295797
Myocardial fibrosis
Tidsskr Nor Laegeforen, 138 (16)
DOI 10.4045/tidsskr.17.1027, PubMed 30344312
The Soft- and Hard-Heartedness of Cardiac Fibroblasts: Mechanotransduction Signaling Pathways in Fibrosis of the Heart
J Clin Med, 6 (5)
DOI 10.3390/jcm6050053, PubMed 28534817
Syndecans in heart fibrosis
Cell Tissue Res, 365 (3), 539-52
DOI 10.1007/s00441-016-2454-2, PubMed 27411689
Other articles
[Espeland and co-workers respond]
Tidsskr Nor Laegeforen, 138 (19)
DOI 10.4045/tidsskr.18.0865, PubMed 30497251