Publication list - Publika - Scientific publications from Oslo University Hospital

Publications by Patrick J. Riss

68 publications found

Original articles

Nagachinta S, Novelli P, Joyard Y, Maindron N, Riss P, Dammicco S (2022)
Fully automated ¹⁸F-fluorination of N-succinimidyl-4-[¹⁸F]fluorobenzoate ([¹⁸F]SFB) for indirect labelling of nanobodies
Sci Rep, 12 (1), 18655
DOI 10.1038/s41598-022-23552-8, PubMed 36333403

Bow JJ, Adami V, Marasco A, Grønnevik G, Rivers DA, Alvaro G, Riss PJ (2022)
A direct fixation of CO₂ for isotopic labelling of hydantoins using iodine-phosphine charge transfer complexes
Chem Commun (Camb), 58 (54), 7546-7549
DOI 10.1039/d2cc01754g, PubMed 35704988

Pérez-García RM, Riss PJ (2022)
Mild, Organo-Catalysed Borono-Deamination as a Key to Late-Stage Pharmaceutical Precursors and ¹⁸F-Labelled Radiotracers
Front Chem, 10, 884478
DOI 10.3389/fchem.2022.884478, PubMed 35559222

Lehnert W, Riss PJ, Hurtado de Mendoza A, Lopez S, Fernandez G, Ilheu M, Amaral H, Kramer V (2022)
Whole-body biodistribution and radiation dosimetry of [¹⁸F]PR04.MZ: a new PET radiotracer for clinical management of patients with movement disorders
EJNMMI Res, 12 (1), 1
DOI 10.1186/s13550-021-00873-9, PubMed 35006412

Juri C, Kramer V, Riss PJ, Soza-Ried C, Haeger A, Pruzzo R, Rösch F, Amaral H, Chana-Cuevas P (2021)
[18F]PR04.MZ PET/CT Imaging for Evaluation of Nigrostriatal Neuron Integrity in Patients With Parkinson Disease
Clin Nucl Med, 46 (2), 119-124
DOI 10.1097/RLU.0000000000003430, PubMed 33323728

Pérez-García RM, Grønnevik G, Riss PJ (2021)
A General Protocol for Cu-Mediated Fluoro-deamination: Sandmeyer Fluorination of Diverse Aromatic Substrates
Org Lett, 23 (3), 1011-1015
DOI 10.1021/acs.orglett.0c04209, PubMed 33492972

Ott J, Spilhaug MM, Maschauer S, Rafique W, Jakobsson JE, Hartvig K, Hübner H, Gmeiner P, Prante O, Riss PJ (2020)
Pharmacological Characterization of Low-to-Moderate Affinity Opioid Receptor Agonists and Brain Imaging with ¹⁸F-Labeled Derivatives in Rats
J Med Chem, 63 (17), 9484-9499
DOI 10.1021/acs.jmedchem.0c00683, PubMed 32787100

Bekker RBW, Fjellaksel R, Hjornevik T, Nuruddin S, Rafique W, Hansen JH, Sundset R, Haraldsen IH, Riss PJ (2020)
Discovery of a Lead Brain-Penetrating Gonadotropin-Releasing Hormone Receptor Antagonist with Saturable Binding in Brain
ChemMedChem, 15 (17), 1624-1628
DOI 10.1002/cmdc.202000256, PubMed 32677155

Waersted FM, Riss PJ, Skipperud L (2020)
The effect of water exchange on the leaching of alum shale
Appl. Geochem., 119, 104610
DOI 10.1016/j.apgeochem.2020.104610

Gurin AN, Riss P, Chakrova ET, Matveyeva IV, Kadyrbaev EA (2020)
Study of the Purification of Lu-177-DOTAELA Complex
Pharm. Chem. J., 54 (1), 64-68
DOI 10.1007/s11094-020-02157-3

Fjellaksel R, Moldes-Anaya A, Vasskog T, Oteiza A, Martin-Armas M, Hjelstuen OK, Hansen JH, Riss PJ, Sundset R (2020)
Evaluation by metabolic profiling and in vitro autoradiography of two promising GnRH-receptor ligands for brain SPECT imaging
J Labelled Comp Radiopharm, 63 (2), 72-84
DOI 10.1002/jlcr.3820, PubMed 31813158

Kramer V, Brooks AF, Haeger A, Kuljis RO, Rafique W, Koeppe RA, Raffel DM, Frey KA, Amaral H, Scott PJH, Riss PJ (2020)
Evaluation of [¹⁸F]-N-Methyl lansoprazole as a Tau PET Imaging Agent in First-in-Human Studies
ACS Chem Neurosci, 11 (3), 427-435
DOI 10.1021/acschemneuro.9b00639, PubMed 31898886

Alluri SR, Pitman KE, Malinen E, Riss PJ (2019)
Synthesis, radiosynthesis, and positron emission tomography neuroimaging using 5-[¹⁸ F]fluoro-L-amino suberate
J Labelled Comp Radiopharm, 63 (1), 6-14
DOI 10.1002/jlcr.3814, PubMed 31697846

Kramer V, Juri C, Riss PJ, Pruzzo R, Soza-Ried C, Flores J, Hurtado A, Rösch F, Chana-Cuevas P, Amaral H (2019)
Pharmacokinetic evaluation of [¹⁸F]PR04.MZ for PET/CT imaging and quantification of dopamine transporters in the human brain
Eur J Nucl Med Mol Imaging, 47 (8), 1927-1937
DOI 10.1007/s00259-019-04594-z, PubMed 31788709

Santangelo AM, Sawiak SJ, Fryer T, Hong Y, Shiba Y, Clarke HF, Riss PJ, Ferrari V, Tait R, Suckling J, Aigbirhio FI, Roberts AC (2019)
Insula serotonin 2A receptor binding and gene expression contribute to serotonin transporter polymorphism anxious phenotype in primates
Proc Natl Acad Sci U S A, 116 (29), 14761-14768
DOI 10.1073/pnas.1902087116, PubMed 31266890

Pitman KE, Alluri SR, Kristian A, Aarnes EK, Lyng H, Riss PJ, Malinen E (2019)
Influx rate of ¹⁸F-fluoroaminosuberic acid reflects cystine/glutamate antiporter expression in tumour xenografts
Eur J Nucl Med Mol Imaging, 46 (10), 2190-2198
DOI 10.1007/s00259-019-04375-8, PubMed 31264167

Jakobsson JE, Gourni E, Khanapur S, Brito B, Riss PJ (2019)
Synthesis and Characterization in Rodent Brain of the Subtype-Selective NR2B NMDA Receptor Ligand [¹¹C]Ro04-5595 as a Potential Radiotracer for Positron Emission Tomography
ACS Omega, 4 (6), 9925-9931
DOI 10.1021/acsomega.9b00357, PubMed 31460083

Gurin AN, Riss P, Chakrova YT, Matveyeva IV (2019)
Quality control test for Lu-177-DOTAELA
Int. J. Biol. Chem., 12 (2), 112-115
DOI 10.26577/ijbch-2019-i2-14

Fjellaksel R, Oteiza A, Martin-Armas M, Riss PJ, Hjelstuen OK, Kuttner S, Hansen JH, Sundset R (2018)
First in vivo evaluation of a potential SPECT brain radiotracer for the gonadotropin releasing hormone receptor
BMC Res Notes, 11 (1), 811
DOI 10.1186/s13104-018-3924-2, PubMed 30442192

Jakobsson JE, Gronnevik G, Rafique W, Hartvig K, Riss PJ (2018)
Formamide as an Unconventional Amine Protecting Group for PET Radiochemistry
Eur. J. Org. Chem., 2018 (27-28), 3701-3704
DOI 10.1002/ejoc.201800554

Rafique W, Kramer V, Pardo T, Smits R, Spilhaug MM, Hoepping A, Savio E, Engler H, Kuljs R, Amaral H, Riss PJ (2018)
Image-Guided Development of Heterocyclic Sulfoxides as Ligands for Tau Neurofibrillary Tangles: From First-in-Man to Second-Generation Ligands
ACS Omega, 3 (7), 7567-7579
DOI 10.1021/acsomega.8b00975, PubMed 30087917

Fjellaksel R, Dugalic D, Demissie TB, Riss PJ, Hjelstuen OK, Sundset R, Hansen JH (2018)
An acylation-Finkelstein approach to radioiodination of bioactives: The role of amide group anchimeric assistance
J. Phys. Org. Chem., 31 (7), e3835
DOI 10.1002/poc.3835

Fjellaksel R, Sundset R, Riss PJ, Hansen JH (2018)
Copper-Mediated Late-Stage Iodination and I-123-Labelling of Triazole-benzimidazole Bioactives
Synlett, 29 (11), 1491-1495
DOI 10.1055/s-0036-1591985

Jakobsson JE, Riss PJ (2018)
Transition metal free, late-stage, regiospecific, aromatic fluorination on a preparative scale using a KF/crypt-222 complex
RSC Adv, 8 (38), 21288-21291
DOI 10.1039/c8ra03757d, PubMed 35539958

Alluri SR, Riss PJ (2018)
Stereospecific radiosynthesis of 3-fluoro amino acids: access to enantiomerically pure radioligands for positron emission tomography
Org Biomol Chem, 16 (13), 2219-2224
DOI 10.1039/C8OB00184G, PubMed 29546903

Alluri SR, Riss PJ (2018)
Poly(ADP-ribose) Polymerase in Neurodegeneration: Radiosynthesis and Radioligand Binding in ARC-SWE tg Mice
ACS Chem Neurosci, 9 (6), 1259-1263
DOI 10.1021/acschemneuro.8b00053, PubMed 29544053

Jakobsson JE, Grønnevik G, Riss PJ (2017)
Organocatalyst-assisted Ar-¹⁸F bond formation: a universal procedure for direct aromatic radiofluorination
Chem Commun (Camb), 53 (96), 12906-12909
DOI 10.1039/c7cc07211b, PubMed 29143838

Fjellaksel R, Boomgaren M, Sundset R, Haraldsen IH, Hansen JH, Riss PJ (2017)
Small molecule piperazinyl-benzimidazole antagonists of the gonadotropin-releasing hormone (GnRH) receptor
Medchemcomm, 8 (10), 1965-1969
DOI 10.1039/c7md00320j, PubMed 30108717

Rafique W, Khanapur S, Spilhaug MM, Riss PJ (2017)
Reaching out for Sensitive Evaluation of the Mu Opioid Receptor in Vivo: Positron Emission Tomography Imaging of the Agonist [¹¹C]AH7921
ACS Chem Neurosci, 8 (9), 1847-1852
DOI 10.1021/acschemneuro.7b00075, PubMed 28590714

Munthe E, Riss PJ, Saga TA, Haraldsen I, Grad I, Bogsrud TV, Bach-Gansmo T (2016)
FDG-based quantitative comparison of glucose metabolism in vitro, exemplified by a head-to-head comparison between a triple-negative breast cancer cell line and a non-malignant foetal cell line
Clin Physiol Funct Imaging, 38 (1), 34-37
DOI 10.1111/cpf.12378, PubMed 27297457

Maschauer S, Haller A, Riss PJ, Kuwert T, Prante O, Cumming P (2015)
Specific binding of [(18)F]fluoroethyl-harmol to monoamine oxidase A in rat brain cryostat sections, and compartmental analysis of binding in living brain
J Neurochem, 135 (5), 908-17
DOI 10.1111/jnc.13370, PubMed 26386360

Sommer T, Bjerregaard-Andersen K, Simensen SM, Jensen JK, Jochimsen B, Riss PJ, Etzerodt M, Morth JP (2015)
Enzymatic detection and quantification assay of isatin, a putative stress biomarker in blood
ACS Chem Neurosci, 6 (8), 1353-60
DOI 10.1021/cn500346x, PubMed 25891478

Li L, Shao X, Cole EL, Ohnmacht SA, Ferrari V, Hong YT, Williamson DJ, Fryer TD, Quesada CA, Sherman P, Riss PJ, Scott PJ, Aigbirhio FI (2015)
Synthesis and Initial in Vivo Studies with [(11)C]SB-216763: The First Radiolabeled Brain Penetrative Inhibitor of GSK-3
ACS Med Chem Lett, 6 (5), 548-52
DOI 10.1021/acsmedchemlett.5b00044, PubMed 26005531

Cumming P, Maschauer S, Riss PJ, Grill E, Pischetsrieder M, Kuwert T, Prante O (2014)
Perturbed Development of Striatal Dopamine Transporters in Fatty Versus Lean Zucker Rats: a Follow-up Small Animal PET Study
Mol Imaging Biol, 17 (4), 521-8
DOI 10.1007/s11307-014-0811-7, PubMed 25537092

Kristian A, Riss P, Qu H, Milde M, Schoultz BW, Engebraaten O, Mælandsmo GM, Malinen E (2014)
Positron emission tomography and pharmacokinetics of 2-[18F]-fluoroethyl choline for metabolic studies in breast cancer xenografts
Acta Oncol, 53 (8), 1086-92
DOI 10.3109/0284186X.2014.934398, PubMed 25017377

Rühl T, Rafique W, Lien VT, Riss PJ (2014)
Cu(I)-mediated (18)F-trifluoromethylation of arenes: rapid synthesis of (18)F-labeled trifluoromethyl arenes
Chem Commun (Camb), 50 (45), 6056-9
DOI 10.1039/c4cc01641f, PubMed 24769775

Cumming P, Maschauer S, Riss PJ, Tschammer N, Fehler SK, Heinrich MR, Kuwert T, Prante O (2014)
Radiosynthesis and validation of ¹⁸F-FP-CMT, a phenyltropane with superior properties for imaging the dopamine transporter in living brain
J Cereb Blood Flow Metab, 34 (7), 1148-56
DOI 10.1038/jcbfm.2014.63, PubMed 24714035

Riss PJ, Brichard L, Ferrari V, Williamson DJ, Fryer TD, Hong YT, Baron JC, Aigbirhio FI (2013)
Radiosynthesis and characterization of astemizole derivatives as lead compounds toward PET imaging of tau-pathology
MedChemComm, 4 (5), 852-855
DOI 10.1039/c3md00017f

Riss PJ, Hoehnemann S, Piel M, Roesch F (2013)
Two-step radiosynthesis of 18)F]FE-β-CIT and [18F]PR04.MZ
J Labelled Comp Radiopharm, 56 (7), 356-9
DOI 10.1002/jlcr.3032, PubMed 24285439

Riss PJ, Hong YT, Marton J, Caprioli D, Williamson DJ, Ferrari V, Saigal N, Roth BL, Henriksen G, Fryer TD, Dalley JW, Aigbirhio FI (2013)
Synthesis and evaluation of 18F-FE-PEO in rodents: an 18F-labeled full agonist for opioid receptor imaging
J Nucl Med, 54 (2), 299-305
DOI 10.2967/jnumed.112.108688, PubMed 23297076

Martins AF, Prata MI, Rodrigues SP, Geraldes CF, Riss PJ, Amor-Coarasa A, Burchardt C, Kroll C, Roesch F (2013)
Spectroscopic, radiochemical, and theoretical studies of the Ga3+-N-2-hydroxyethyl piperazine-N'-2-ethanesulfonic acid (HEPES buffer) system: evidence for the formation of Ga3+ - HEPES complexes in (68) Ga labeling reactions
Contrast Media Mol Imaging, 8 (3), 265-73
DOI 10.1002/cmmi.1517, PubMed 23606430

Zoller F, Riss PJ, Montforts FP, Kelleher DK, Eppard E, Rösch F (2012)
Radiolabelling and preliminary evaluation of 68Ga-tetrapyrrole derivatives as potential tracers for PET
Nucl Med Biol, 40 (2), 280-8
DOI 10.1016/j.nucmedbio.2012.11.006, PubMed 23265666

Riss PJ, Ferrari V, Brichard L, Burke P, Smith R, Aigbirhio FI (2012)
Direct, nucleophilic radiosynthesis of [18F]trifluoroalkyl tosylates: improved labelling procedures
Org Biomol Chem, 10 (34), 6980-6
DOI 10.1039/c2ob25802a, PubMed 22833145

Riss PJ, Lu S, Telu S, Aigbirhio FI, Pike VW (2012)
Cu(I)-catalyzed (11)C carboxylation of boronic acid esters: a rapid and convenient entry to (11)C-labeled carboxylic acids, esters, and amides
Angew Chem Int Ed Engl, 51 (11), 2698-702
DOI 10.1002/anie.201107263, PubMed 22308017

Riss PJ, Hooker JM, Shea C, Xu Y, Carter P, Warner D, Ferrari V, Kim SW, Aigbirhio FI, Fowler JS, Roesch F (2011)
Characterisation of [¹¹C]PR04.MZ in Papio anubis baboon: a selective high-affinity radioligand for quantitative imaging of the dopamine transporter
Bioorg Med Chem Lett, 22 (1), 679-82
DOI 10.1016/j.bmcl.2011.10.053, PubMed 22082561

Riss PJ, Aigbirhio FI (2011)
A simple, rapid procedure for nucleophilic radiosynthesis of aliphatic [18F]trifluoromethyl groups
Chem Commun (Camb), 47 (43), 11873-5
DOI 10.1039/c1cc15342k, PubMed 21987078

Riss PJ, Hong YT, Williamson D, Caprioli D, Sitnikov S, Ferrari V, Sawiak SJ, Baron JC, Dalley JW, Fryer TD, Aigbirhio FI (2011)
Validation and quantification of [18F]altanserin binding in the rat brain using blood input and reference tissue modeling
J Cereb Blood Flow Metab, 31 (12), 2334-42
DOI 10.1038/jcbfm.2011.94, PubMed 21750562

Riss PJ, Burchardt C, Roesch F (2011)
A methodical 68Ga-labelling study of DO2A-(butyl-L-tyrosine)2 with cation-exchanger post-processed 68Ga: practical aspects of radiolabelling
Contrast Media Mol Imaging, 6 (6), 492-8
DOI 10.1002/cmmi.451, PubMed 22144027

Riss PJ, Piel M, Bockhart V, Bausbacher N, Buchholz HG, Lueddens H, Roesch F (2010)
The DAT ligand [(18)F]PR17.MZ mirrors the in vivo pharmacokinetic profile of [(11)C]cocaine with significantly improved monoamine transporter selectivity
ChemMedChem, 5 (10), 1686-8
DOI 10.1002/cmdc.201000237, PubMed 20830722

Notni J, Hermann P, Havlícková J, Kotek J, Kubícek V, Plutnar J, Loktionova N, Riss PJ, Rösch F, Lukes I (2010)
A triazacyclononane-based bifunctional phosphinate ligand for the preparation of multimeric 68Ga tracers for positron emission tomography
Chemistry, 16 (24), 7174-85
DOI 10.1002/chem.200903281, PubMed 20461824

Riss PJ, Roesch F (2009)
Efficient microwave-assisted direct radiosynthesis of [(18)F]PR04.MZ and [(18)F]LBT999: selective dopamine transporter ligands for quantitative molecular imaging by means of PET
Bioorg Med Chem, 17 (22), 7630-4
DOI 10.1016/j.bmc.2009.09.054, PubMed 19846314

Riss PJ, Debus F, Hummerich R, Schmidt U, Schloss P, Lueddens H, Roesch F (2009)
Ex vivo and in vivo evaluation of [18F]PR04.MZ in rodents: a selective dopamine transporter imaging agent
ChemMedChem, 4 (9), 1480-7
DOI 10.1002/cmdc.200900177, PubMed 19588472

Riss PJ, Hooker JM, Alexoff D, Kim SW, Fowler JS, Rösch F (2009)
[(11)C]PR04.MZ, a promising DAT ligand for low concentration imaging: Synthesis, efficient (11)C-O-methylation and initial small animal PET studies
Bioorg Med Chem Lett, 19 (15), 4343-5
DOI 10.1016/j.bmcl.2009.05.090, PubMed 19525112

Burchardt C, Riss PJ, Zoller F, Maschauer S, Prante O, Kuwert T, Roesch F (2009)
[(68)Ga]Ga-DO(2)A-(OBu-l-tyr)(2): synthesis, (68)Ga-radiolabeling and in vitro studies of a novel (68)Ga-DO(2)A-tyrosine conjugate as potential tumor tracer for PET
Bioorg Med Chem Lett, 19 (13), 3498-501
DOI 10.1016/j.bmcl.2009.05.001, PubMed 19477125

Riss PJ, Hummerich R, Schloss P (2009)
Synthesis and monoamine uptake inhibition of conformationally constrained 2beta-carbomethoxy-3beta-phenyl tropanes
Org Biomol Chem, 7 (13), 2688-98
DOI 10.1039/b902863c, PubMed 19532984

Herth MM, Kramer V, Piel M, Palner M, Riss PJ, Knudsen GM, Rösch F (2009)
Synthesis and in vitro affinities of various MDL 100907 derivatives as potential 18F-radioligands for 5-HT2A receptor imaging with PET
Bioorg Med Chem, 17 (8), 2989-3002
DOI 10.1016/j.bmc.2009.03.021, PubMed 19329329

Riss PJ, Rösch F (2008)
A convenient chemo-enzymatic synthesis and 18F-labelling of both enantiomers of trans-1-toluenesulfonyloxymethyl-2-fluoromethyl-cyclopropane
Org Biomol Chem, 6 (24), 4567-74
DOI 10.1039/b812777h, PubMed 19039365

Riss PJ, Kroll C, Nagel V, Rösch F (2008)
NODAPA-OH and NODAPA-(NCS)n: synthesis, 68Ga-radiolabelling and in vitro characterisation of novel versatile bifunctional chelators for molecular imaging
Bioorg Med Chem Lett, 18 (20), 5364-7
DOI 10.1016/j.bmcl.2008.09.054, PubMed 18835159

Review articles

Tukun FL, Olberg DE, Riss PJ, Haraldsen I, Kaass A, Klaveness J (2017)
Recent Development of Non-Peptide GnRH Antagonists
Molecules, 22 (12)
DOI 10.3390/molecules22122188, PubMed 29232843

Lien VT, Riss PJ (2014)
Radiosynthesis of [18)F]trifluoroalkyl groups: scope and limitations
Biomed Res Int, 2014, 380124
DOI 10.1155/2014/380124, PubMed 25110676

Riss PJ, Stockhofe K, Roesch F (2013)
Tropane-derived (11) C-labelled and (18) F-labelled DAT ligands
J Labelled Comp Radiopharm, 56 (3-4), 149-58
DOI 10.1002/jlcr.3018, PubMed 24285320

Virdee K, Cumming P, Caprioli D, Jupp B, Rominger A, Aigbirhio FI, Fryer TD, Riss PJ, Dalley JW (2012)
Applications of positron emission tomography in animal models of neurological and neuropsychiatric disorders
Neurosci Biobehav Rev, 36 (4), 1188-216
DOI 10.1016/j.neubiorev.2012.01.009, PubMed 22342372

Buell AK, Esbjörner EK, Riss PJ, White DA, Aigbirhio FI, Toth G, Welland ME, Dobson CM, Knowles TP (2011)
Probing small molecule binding to amyloid fibrils
Phys Chem Chem Phys, 13 (45), 20044-52
DOI 10.1039/c1cp22283j, PubMed 22006124

Roesch F, Riss PJ (2010)
The renaissance of the ⁶⁸Ge/⁶⁸Ga radionuclide generator initiates new developments in ⁶⁸Ga radiopharmaceutical chemistry
Curr Top Med Chem, 10 (16), 1633-68
DOI 10.2174/156802610793176738, PubMed 20583984