Publications by Françoise Dantzer
70 publications found
Original articles
PARP2 downregulation in T cells ameliorates lipopolysaccharide-induced inflammation of the large intestine
Front Immunol, 14, 1135410
DOI 10.3389/fimmu.2023.1135410, PubMed 37457706
Purification of Recombinant Human PARG and Activity Assays
Methods Mol Biol, 2609, 399-418
DOI 10.1007/978-1-0716-2891-1_25, PubMed 36515850
Purification of Recombinant Human PARP-3
Methods Mol Biol, 2609, 419-441
DOI 10.1007/978-1-0716-2891-1_26, PubMed 36515851
PARP3 supervises G9a-mediated repression of adhesion and hypoxia-responsive genes in glioblastoma cells
Sci Rep, 12 (1), 15534
DOI 10.1038/s41598-022-19525-6, PubMed 36109561
Distinct roles for PARP-1 and PARP-2 in c-Myc-driven B-cell lymphoma in mice
Blood, 139 (2), 228-239
DOI 10.1182/blood.2021012805, PubMed 34359075
Deficiency of PARP-1 and PARP-2 in the mouse uterus results in decidualization failure and pregnancy loss
Proc Natl Acad Sci U S A, 118 (40)
DOI 10.1073/pnas.2109252118, PubMed 34580230
ADP-ribosyltransferases, an update on function and nomenclature
FEBS J, 289 (23), 7399-7410
DOI 10.1111/febs.16142, PubMed 34323016
Selective modulation by PARP-1 of HIF-1α-recruitment to chromatin during hypoxia is required for tumor adaptation to hypoxic conditions
Redox Biol, 41, 101885
DOI 10.1016/j.redox.2021.101885, PubMed 33581682
Parp3 promotes astrocytic differentiation through a tight regulation of Nox4-induced ROS and mTorc2 activation
Cell Death Dis, 11 (11), 954
DOI 10.1038/s41419-020-03167-5, PubMed 33159039
Coordinated signals from PARP-1 and PARP-2 are required to establish a proper T cell immune response to breast tumors in mice
Oncogene, 39 (13), 2835-2843
DOI 10.1038/s41388-020-1175-x, PubMed 32001817
Coordinated signals from the DNA repair enzymes PARP-1 and PARP-2 promotes B-cell development and function
Cell Death Differ, 26 (12), 2667-2681
DOI 10.1038/s41418-019-0326-5, PubMed 30996287
PARP3, a new therapeutic target to alter Rictor/mTORC2 signaling and tumor progression in BRCA1-associated cancers
Cell Death Differ, 26 (9), 1615-1630
DOI 10.1038/s41418-018-0233-1, PubMed 30442946
PARP2 mediates branched poly ADP-ribosylation in response to DNA damage
Nat Commun, 9 (1), 3233
DOI 10.1038/s41467-018-05588-5, PubMed 30104678
PARP-1 protects against colorectal tumor induction, but promotes inflammation-driven colorectal tumor progression
Proc Natl Acad Sci U S A, 115 (17), E4061-E4070
DOI 10.1073/pnas.1712345115, PubMed 29632181
PARP2 deficiency affects invariant-NKT-cell maturation and protects mice from concanavalin A-induced liver injury
Am J Physiol Gastrointest Liver Physiol, 313 (5), G399-G409
DOI 10.1152/ajpgi.00436.2016, PubMed 28751426
Robust immunoglobulin class switch recombination and end joining in Parp9-deficient mice
Eur J Immunol, 47 (4), 665-676
DOI 10.1002/eji.201646757, PubMed 28105679
PARP-1/PARP-2 double deficiency in mouse T cells results in faulty immune responses and T lymphomas
Sci Rep, 7, 41962
DOI 10.1038/srep41962, PubMed 28181505
Purification of Recombinant Human PARP-3
Methods Mol Biol, 1608, 373-394
DOI 10.1007/978-1-4939-6993-7_24, PubMed 28695522
Purification of Recombinant Human PARG and Activity Assays
Methods Mol Biol, 1608, 395-413
DOI 10.1007/978-1-4939-6993-7_25, PubMed 28695523
Autophagy requires poly(adp-ribosyl)ation-dependent AMPK nuclear export
Cell Death Differ, 23 (12), 2007-2018
DOI 10.1038/cdd.2016.80, PubMed 27689873
PARP3 controls TGFβ and ROS driven epithelial-to-mesenchymal transition and stemness by stimulating a TG2-Snail-E-cadherin axis
Oncotarget, 7 (39), 64109-64123
DOI 10.18632/oncotarget.11627, PubMed 27579892
PARG deficiency is neither synthetic lethal with BRCA1 nor PTEN deficiency
Cancer Cell Int, 16, 53
DOI 10.1186/s12935-016-0333-2, PubMed 27375368
Distinct mechanisms for opposite functions of homeoproteins Cdx2 and HoxB7 in double-strand break DNA repair in colon cancer cells
Cancer Lett, 374 (2), 208-15
DOI 10.1016/j.canlet.2016.02.026, PubMed 26902420
Parp3 negatively regulates immunoglobulin class switch recombination
PLoS Genet, 11 (5), e1005240
DOI 10.1371/journal.pgen.1005240, PubMed 26000965
PARG is dispensable for recovery from transient replicative stress but required to prevent detrimental accumulation of poly(ADP-ribose) upon prolonged replicative stress
Nucleic Acids Res, 42 (12), 7776-92
DOI 10.1093/nar/gku505, PubMed 24906880
NAD(+)-dependent activation of Sirt1 corrects the phenotype in a mouse model of mitochondrial disease
Cell Metab, 19 (6), 1042-9
DOI 10.1016/j.cmet.2014.04.001, PubMed 24814483
Poly(ADP-ribose) polymerase 1 (PARP1) associates with E3 ubiquitin-protein ligase UHRF1 and modulates UHRF1 biological functions
J Biol Chem, 289 (23), 16223-38
DOI 10.1074/jbc.M113.527424, PubMed 24782312
PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways
Nucleic Acids Res, 42 (9), 5616-32
DOI 10.1093/nar/gku174, PubMed 24598253
Cell death associated with abnormal mitosis observed by confocal imaging in live cancer cells
J Vis Exp (78), e50568
DOI 10.3791/50568, PubMed 23995751
Parp-2 is required to maintain hematopoiesis following sublethal γ-irradiation in mice
Blood, 122 (1), 44-54
DOI 10.1182/blood-2012-12-472845, PubMed 23678004
The level of Ets-1 protein is regulated by poly(ADP-ribose) polymerase-1 (PARP-1) in cancer cells to prevent DNA damage
PLoS One, 8 (2), e55883
DOI 10.1371/journal.pone.0055883, PubMed 23405229
Decreasing Poly(ADP-Ribose) Polymerase Activity Restores ΔF508 CFTR Trafficking
Front Pharmacol, 3, 165
DOI 10.3389/fphar.2012.00165, PubMed 22988441
A phenanthrene derived PARP inhibitor is an extra-centrosomes de-clustering agent exclusively eradicating human cancer cells
BMC Cancer, 11, 412
DOI 10.1186/1471-2407-11-412, PubMed 21943092
Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression
Proc Natl Acad Sci U S A, 108 (7), 2783-8
DOI 10.1073/pnas.1016574108, PubMed 21270334
Purification of recombinant poly(ADP-ribose) polymerases
Methods Mol Biol, 780, 135-52
DOI 10.1007/978-1-61779-270-0_9, PubMed 21870259
Phenotypic characterization of Parp-1 and Parp-2 deficient mice and cells
Methods Mol Biol, 780, 313-36
DOI 10.1007/978-1-61779-270-0_19, PubMed 21870269
Functional interplay between Parp-1 and SirT1 in genome integrity and chromatin-based processes
Cell Mol Life Sci, 66 (19), 3219-34
DOI 10.1007/s00018-009-0105-4, PubMed 19672559
Parp2 is required for the differentiation of post-meiotic germ cells: identification of a spermatid-specific complex containing Parp1, Parp2, TP2 and HSPA2
Exp Cell Res, 315 (16), 2824-34
DOI 10.1016/j.yexcr.2009.07.003, PubMed 19607827
Radiation-induced mitotic catastrophe in PARG-deficient cells
J Cell Sci, 122 (Pt 12), 1990-2002
DOI 10.1242/jcs.039115, PubMed 19454480
Parp1 facilitates alternative NHEJ, whereas Parp2 suppresses IgH/c-myc translocations during immunoglobulin class switch recombination
J Exp Med, 206 (5), 1047-56
DOI 10.1084/jem.20082468, PubMed 19364882
A selective eradication of human nonhereditary breast cancer cells by phenanthridine-derived polyADP-ribose polymerase inhibitors
Breast Cancer Res, 11 (6), R78
DOI 10.1186/bcr2445, PubMed 19891779
Detection of the nuclear poly(ADP-ribose)-metabolizing enzymes and activities in response to DNA damage
Methods Mol Biol, 464, 267-83
DOI 10.1007/978-1-60327-461-6_15, PubMed 18951190
Hsp70 translocates to the nuclei and nucleoli, binds to XRCC1 and PARP-1, and protects HeLa cells from single-strand DNA breaks
Cell Stress Chaperones, 14 (4), 391-406
DOI 10.1007/s12192-008-0093-6, PubMed 19089598
Poly(ADP-ribose) polymerase-1 (Parp-1)-deficient mice demonstrate abnormal antibody responses
Immunology, 127 (2), 178-86
DOI 10.1111/j.1365-2567.2008.02921.x, PubMed 18778284
The histone subcode: poly(ADP-ribose) polymerase-1 (Parp-1) and Parp-2 control cell differentiation by regulating the transcriptional intermediary factor TIF1beta and the heterochromatin protein HP1alpha
FASEB J, 22 (11), 3853-65
DOI 10.1096/fj.08-113464, PubMed 18676401
Poly(ADP-ribose) polymerase-2 contributes to the fidelity of male meiosis I and spermiogenesis
Proc Natl Acad Sci U S A, 103 (40), 14854-9
DOI 10.1073/pnas.0604252103, PubMed 17001008
Control of AIF-mediated cell death by the functional interplay of SIRT1 and PARP-1 in response to DNA damage
Cell Cycle, 5 (8), 873-7
DOI 10.4161/cc.5.8.2690, PubMed 16628003
PARP1 Is a TRF2-associated poly(ADP-ribose)polymerase and protects eroded telomeres
Mol Biol Cell, 17 (4), 1686-96
DOI 10.1091/mbc.e05-07-0672, PubMed 16436506
Poly(ADP-ribose) polymerase-1 activation during DNA damage and repair
Methods Enzymol, 409, 493-510
DOI 10.1016/S0076-6879(05)09029-4, PubMed 16793420
Dynamic relocalization of hOGG1 during the cell cycle is disrupted in cells harbouring the hOGG1-Cys326 polymorphic variant
Nucleic Acids Res, 33 (6), 1813-24
DOI 10.1093/nar/gki325, PubMed 15800211
Functional interaction between poly(ADP-Ribose) polymerase 2 (PARP-2) and TRF2: PARP activity negatively regulates TRF2
Mol Cell Biol, 24 (4), 1595-607
DOI 10.1128/MCB.24.4.1595-1607.2004, PubMed 14749375
Comparative analysis of 8-oxoG:C, 8-oxoG:A, A:C and C:C DNA repair in extracts from wild type or 8-oxoG DNA glycosylase deficient mammalian and bacterial cells
DNA Repair (Amst), 2 (6), 707-18
DOI 10.1016/s1568-7864(03)00041-7, PubMed 12767349
Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse
EMBO J, 22 (9), 2255-63
DOI 10.1093/emboj/cdg206, PubMed 12727891
Human OGG1 undergoes serine phosphorylation and associates with the nuclear matrix and mitotic chromatin in vivo
Nucleic Acids Res, 30 (11), 2349-57
DOI 10.1093/nar/30.11.2349, PubMed 12034821
Review articles
PARP1 and Poly(ADP-ribosyl)ation Signaling during Autophagy in Response to Nutrient Deprivation
Oxid Med Cell Longev, 2019, 2641712
DOI 10.1155/2019/2641712, PubMed 31281570
PARP3 comes to light as a prime target in cancer therapy
Cell Cycle, 18 (12), 1295-1301
DOI 10.1080/15384101.2019.1617454, PubMed 31095444
[From poly(ADP-ribose) discovery to PARP inhibitors in cancer therapy]
Bull Cancer, 102 (10), 863-73
DOI 10.1016/j.bulcan.2015.07.012, PubMed 26384693
Poly(ADP-ribose) polymerases in double-strand break repair: focus on PARP1, PARP2 and PARP3
Exp Cell Res, 329 (1), 18-25
DOI 10.1016/j.yexcr.2014.07.003, PubMed 25017100
The expanding role of PARPs in the establishment and maintenance of heterochromatin
FEBS J, 280 (15), 3508-18
DOI 10.1111/febs.12368, PubMed 23731385
Functional aspects of PARylation in induced and programmed DNA repair processes: preserving genome integrity and modulating physiological events
Mol Aspects Med, 34 (6), 1138-52
DOI 10.1016/j.mam.2013.02.001, PubMed 23454615
New readers and interpretations of poly(ADP-ribosyl)ation
Trends Biochem Sci, 37 (9), 381-90
DOI 10.1016/j.tibs.2012.06.001, PubMed 22766145
The diverse roles and clinical relevance of PARPs in DNA damage repair: current state of the art
Biochem Pharmacol, 84 (2), 137-46
DOI 10.1016/j.bcp.2012.03.018, PubMed 22469522
[PARP inhibitors: significant progress in cancer therapy]
Bull Cancer, 98 (3), 277-90
DOI 10.1684/bdc.2011.1330, PubMed 21459712
The expanding field of poly(ADP-ribosyl)ation reactions. 'Protein Modifications: Beyond the Usual Suspects' Review Series
EMBO Rep, 9 (11), 1094-100
DOI 10.1038/embor.2008.191, PubMed 18927583
The role of poly(ADP-ribosyl)ation in epigenetic events
Int J Biochem Cell Biol, 41 (1), 60-5
DOI 10.1016/j.biocel.2008.07.023, PubMed 18775502
Toward specific functions of poly(ADP-ribose) polymerase-2
Trends Mol Med, 14 (4), 169-78
DOI 10.1016/j.molmed.2008.02.003, PubMed 18353725
Poly(ADP-ribose): novel functions for an old molecule
Nat Rev Mol Cell Biol, 7 (7), 517-28
DOI 10.1038/nrm1963, PubMed 16829982
Other articles
Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts
bioRxiv
DOI 10.1101/2024.03.12.584665, PubMed 38559022
[Not Available]
Bull Cancer, 107 (2), 283-287
DOI 10.1016/j.bulcan.2020.01.003, PubMed 32014246
PARP-3, a DNA-dependent PARP with emerging roles in double-strand break repair and mitotic progression
Cell Cycle, 10 (7), 1023-4
DOI 10.4161/cc.10.7.15169, PubMed 21358266