Publika - Scientific publications from Oslo University Hospital

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Publications by Sjur Olsnes

263 publications found

Original articles

Sletten T, Kostas M, Bober J, Sorensen V, Yadollahi M, Olsnes S, Tomala J, Otlewski J, Zakrzewska M, Wiedlocha A (2014)
Nucleolin regulates phosphorylation and nuclear export of fibroblast growth factor 1 (FGF1)
PLoS One, 9 (3), e90687
DOI 10.1371/journal.pone.0090687, PubMed 24595027

Zhen Y, Sørensen V, Skjerpen CS, Haugsten EM, Jin Y, Wälchli S, Olsnes S, Wiedlocha A (2012)
Nuclear import of exogenous FGF1 requires the ER-protein LRRC59 and the importins Kpnα1 and Kpnβ1
Traffic, 13 (5), 650-64
DOI 10.1111/j.1600-0854.2012.01341.x, PubMed 22321063

Zakrzewska M, Sørensen V, Jin Y, Wiedlocha A, Olsnes S (2011)
Translocation of exogenous FGF1 into cytosol and nucleus is a periodic event independent of receptor kinase activity
Exp Cell Res, 317 (7), 1005-15
DOI 10.1016/j.yexcr.2011.01.003, PubMed 21223966

Haugsten EM, Zakrzewska M, Brech A, Pust S, Olsnes S, Sandvig K, Wesche J (2011)
Clathrin- and dynamin-independent endocytosis of FGFR3--implications for signalling
PLoS One, 6 (7), e21708
DOI 10.1371/journal.pone.0021708, PubMed 21779335

Iglesias R, Citores L, Ferreras JM, Pérez Y, Jiménez P, Gayoso MJ, Olsnes S, Tamburino R, Di Maro A, Parente A, Girbés T (2009)
Sialic acid-binding dwarf elder four-chain lectin displays nucleic acid N-glycosidase activity
Biochimie, 92 (1), 71-80
DOI 10.1016/j.biochi.2009.09.011, PubMed 19799962

Zakrzewska M, Zhen Y, Wiedlocha A, Olsnes S, Wesche J (2009)
Size limitation in translocation of fibroblast growth factor 1 fusion proteins across the endosomal membrane
Biochemistry, 48 (30), 7209-18
DOI 10.1021/bi9007353, PubMed 19558187

Zakrzewska M, Wiedlocha A, Szlachcic A, Krowarsch D, Otlewski J, Olsnes S (2009)
Increased protein stability of FGF1 can compensate for its reduced affinity for heparin
J Biol Chem, 284 (37), 25388-403
DOI 10.1074/jbc.M109.001289, PubMed 19574212

Haugsten EM, Malecki J, Bjørklund SM, Olsnes S, Wesche J (2008)
Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosis
Mol Biol Cell, 19 (8), 3390-403
DOI 10.1091/mbc.e07-12-1219, PubMed 18480409

Sørensen V, Zhen Y, Zakrzewska M, Haugsten EM, Wälchli S, Nilsen T, Olsnes S, Wiedlocha A (2008)
Phosphorylation of fibroblast growth factor (FGF) receptor 1 at Ser777 by p38 mitogen-activated protein kinase regulates translocation of exogenous FGF1 to the cytosol and nucleus
Mol Cell Biol, 28 (12), 4129-41
DOI 10.1128/MCB.02117-07, PubMed 18411303

Nilsen T, Rosendal KR, Sørensen V, Wesche J, Olsnes S, Wiedłocha A (2007)
A nuclear export sequence located on a beta-strand in fibroblast growth factor-1
J Biol Chem, 282 (36), 26245-56
DOI 10.1074/jbc.M611234200, PubMed 17616529

Citores L, Bai L, Sørensen V, Olsnes S (2007)
Fibroblast growth factor receptor-induced phosphorylation of STAT1 at the Golgi apparatus without translocation to the nucleus
J Cell Physiol, 212 (1), 148-56
DOI 10.1002/jcp.21014, PubMed 17311277

Kurmanova A, Llorente A, Polesskaya A, Garred O, Olsnes S, Kozlov J, Sandvig K (2007)
Structural requirements for furin-induced cleavage and activation of Shiga toxin
Biochem Biophys Res Commun, 357 (1), 144-9
DOI 10.1016/j.bbrc.2007.03.110, PubMed 17407762

Zakrzewska M, Krowarsch D, Wiedlocha A, Olsnes S, Otlewski J (2006)
Structural requirements of FGF-1 for receptor binding and translocation into cells
Biochemistry, 45 (51), 15338-48
DOI 10.1021/bi0618114, PubMed 17176056

Sørensen V, Wiedlocha A, Haugsten EM, Khnykin D, Wesche J, Olsnes S (2006)
Different abilities of the four FGFRs to mediate FGF-1 translocation are linked to differences in the receptor C-terminal tail
J Cell Sci, 119 (Pt 20), 4332-41
DOI 10.1242/jcs.03209, PubMed 17003104

Khnykin D, Olsnes S (2006)
Reduced binding of FGF1 to mutant fibroblast growth factor receptor 3
Growth Factors, 24 (2), 111-9
DOI 10.1080/08977190600621388, PubMed 16801131

Wesche J, Małecki J, Wiedłocha A, Skjerpen CS, Claus P, Olsnes S (2006)
FGF-1 and FGF-2 require the cytosolic chaperone Hsp90 for translocation into the cytosol and the cell nucleus
J Biol Chem, 281 (16), 11405-12
DOI 10.1074/jbc.M600477200, PubMed 16495214

Zakrzewska M, Krowarsch D, Wiedlocha A, Olsnes S, Otlewski J (2005)
Highly stable mutants of human fibroblast growth factor-1 exhibit prolonged biological action
J Mol Biol, 352 (4), 860-75
DOI 10.1016/j.jmb.2005.07.066, PubMed 16126225

Haugsten EM, Sørensen V, Brech A, Olsnes S, Wesche J (2005)
Different intracellular trafficking of FGF1 endocytosed by the four homologous FGF receptors
J Cell Sci, 118 (Pt 17), 3869-81
DOI 10.1242/jcs.02509, PubMed 16091423

Wesche J, Małecki J, Wiedłocha A, Ehsani M, Marcinkowska E, Nilsen T, Olsnes S (2005)
Two nuclear localization signals required for transport from the cytosol to the nucleus of externally added FGF-1 translocated into cells
Biochemistry, 44 (16), 6071-80
DOI 10.1021/bi047403m, PubMed 15835896

Korobko E, Kiselev S, Olsnes S, Stenmark H, Korobko I (2005)
The Rab5 effector Rabaptin-5 and its isoform Rabaptin-5delta differ in their ability to interact with the small GTPase Rab4
FEBS J, 272 (1), 37-46
DOI 10.1111/j.1742-4658.2004.04387.x, PubMed 15634330

Wiedłocha A, Nilsen T, Wesche J, Sørensen V, Małecki J, Marcinkowska E, Olsnes S (2004)
Phosphorylation-regulated nucleocytoplasmic trafficking of internalized fibroblast growth factor-1
Mol Biol Cell, 16 (2), 794-810
DOI 10.1091/mbc.e04-05-0389, PubMed 15574884

Kourmanova AG, Soudarkina OJ, Olsnes S, Kozlov JV (2004)
Cloning and characterization of the genes encoding toxic lectins in mistletoe (Viscum album L)
Eur J Biochem, 271 (12), 2350-60
DOI 10.1111/j.1432-1033.2004.04153.x, PubMed 15182350

Sørensen V, Brech A, Khnykin D, Kolpakova E, Citores L, Olsnes S (2004)
Deletion mutant of FGFR4 induces onion-like membrane structures in the nucleus
J Cell Sci, 117 (Pt 9), 1807-19
DOI 10.1242/jcs.01047, PubMed 15075241

Małecki J, Wesche J, Skjerpen CS, Wiedłocha A, Olsnes S (2003)
Translocation of FGF-1 and FGF-2 across vesicular membranes occurs during G1-phase by a common mechanism
Mol Biol Cell, 15 (2), 801-14
DOI 10.1091/mbc.e03-08-0589, PubMed 14657241

Nilsen T, Slagsvold T, Skjerpen CS, Brech A, Stenmark H, Olsnes S (2003)
Peroxisomal targeting as a tool for assaying potein-protein interactions in the living cell: cytokine-independent survival kinase (CISK) binds PDK-1 in vivo in a phosphorylation-dependent manner
J Biol Chem, 279 (6), 4794-801
DOI 10.1074/jbc.M309653200, PubMed 14604990

Kolpakova E, Rusten TE, Olsnes S (2003)
Characterization and tissue expression of acidic fibroblast growth factor binding protein homologue in Drosophila melanogaster
Gene, 310, 185-91
DOI 10.1016/s0378-1119(03)00550-x, PubMed 12801646

Małecki J, Wiedłocha A, Wesche J, Olsnes S (2002)
Vesicle transmembrane potential is required for translocation to the cytosol of externally added FGF-1
EMBO J, 21 (17), 4480-90
DOI 10.1093/emboj/cdf472, PubMed 12198150

Skjerpen CS, Nilsen T, Wesche J, Olsnes S (2002)
Binding of FGF-1 variants to protein kinase CK2 correlates with mitogenicity
EMBO J, 21 (15), 4058-69
DOI 10.1093/emboj/cdf402, PubMed 12145206

Skjerpen CS, Wesche J, Olsnes S (2002)
Identification of ribosome-binding protein p34 as an intracellular protein that binds acidic fibroblast growth factor
J Biol Chem, 277 (26), 23864-71
DOI 10.1074/jbc.M112193200, PubMed 11964394

Luk'ianov EV, Viedlokha A, Kuianskaia DV, Olsnes S, Kozlov IuV (2002)
[A short form of the heparin-binding EGF-like growth factor with a changed EGF domain]
Mol Biol (Mosk), 36 (1), 76-83
PubMed 11862716

Luk'yanov EV, Viedlokha A, Kuyavskaya DV, Olsnes S, Kozlov YV (2002)
A short form of the heparin-binding EGF-like growth factor with a changed EGF domain
Mol. Biol., 36 (1), 58-64
DOI 10.1023/A:1014246423243

Olsnes S, Kozlov JV (2001)
Ricin
Toxicon, 39 (11), 1723-8
DOI 10.1016/s0041-0101(01)00158-1, PubMed 11595634

Citores L, Khnykin D, Sørensen V, Wesche J, Klingenberg O, Wiedłocha A, Olsnes S (2001)
Modulation of intracellular transport of acidic fibroblast growth factor by mutations in the cytoplasmic receptor domain
J Cell Sci, 114 (Pt 9), 1677-89
DOI 10.1242/jcs.114.9.1677, PubMed 11398757

Falnes PØ, Wesche J, Olsnes S (2001)
Ability of the Tat basic domain and VP22 to mediate cell binding, but not membrane translocation of the diphtheria toxin A-fragment
Biochemistry, 40 (14), 4349-58
DOI 10.1021/bi002443l, PubMed 11284691

Loukianov EV, Wiedlocha A, Olsnes S, Kozlov YV (2001)
Two farms of the heparin-binding EGF-like growth factor precursor, a receptor for diphtheria toxin
Mol. Biol., 35 (1), 122-129
DOI 10.1023/A:1004819321876

Luk'ianov EV, Viedlokha A, Olsnes S, Kozlov IuV (2001)
[Two forms of precursors of a heparin-binding EGF-like growth factor-diphtheria toxin receptor]
Mol Biol (Mosk), 35 (1), 136-45
PubMed 11234372

Kolpakova E, Frengen E, Stokke T, Olsnes S (2000)
Organization, chromosomal localization and promoter analysis of the gene encoding human acidic fibroblast growth factor intracellular binding protein
Biochem J, 352 Pt 3 (Pt 3), 629-35
DOI 10.1042/0264-6021:3520629, PubMed 11104667

Wesche J, Wiedłocha A, Falnes PO, Choe S, Olsnes S (2000)
Externally added aFGF mutants do not require extensive unfolding for transport to the cytosol and the nucleus in NIH/3T3 cells
Biochemistry, 39 (49), 15091-100
DOI 10.1021/bi001831k, PubMed 11106487

Day PJ, Owens SR, Wesche J, Olsnes S, Roberts LM, Lord JM (2000)
An interaction between ricin and calreticulin that may have implications for toxin trafficking
J Biol Chem, 276 (10), 7202-8
DOI 10.1074/jbc.M009499200, PubMed 11113144

Klingenberg O, Wiedlocha A, Rapak A, Khnykin D, Citores L, Olsnes S (2000)
Requirement for C-terminal end of fibroblast growth factor receptor 4 in translocation of acidic fibroblast growth factor to cytosol and nucleus
J Cell Sci, 113 ( Pt 10), 1827-38
DOI 10.1242/jcs.113.10.1827, PubMed 10769213

Falnes PO, Ariansen S, Sandvig K, Olsnes S (2000)
Requirement for prolonged action in the cytosol for optimal protein synthesis inhibition by diphtheria toxin
J Biol Chem, 275 (6), 4363-8
DOI 10.1074/jbc.275.6.4363, PubMed 10660606

Olsnes S (1999)
[The Nobel Prize in physiology and medicine]
Tidsskr Nor Laegeforen, 119 (30), 4450
PubMed 10827478

Wesche J, Rapak A, Olsnes S (1999)
Dependence of ricin toxicity on translocation of the toxin A-chain from the endoplasmic reticulum to the cytosol
J Biol Chem, 274 (48), 34443-9
DOI 10.1074/jbc.274.48.34443, PubMed 10567425

Citores L, Wesche J, Kolpakova E, Olsnes S (1999)
Uptake and intracellular transport of acidic fibroblast growth factor: evidence for free and cytoskeleton-anchored fibroblast growth factor receptors
Mol Biol Cell, 10 (11), 3835-48
DOI 10.1091/mbc.10.11.3835, PubMed 10564275

Falnes PO, Welker R, Kräusslich HG, Olsnes S (1999)
Toxins that are activated by HIV type-1 protease through removal of a signal for degradation by the N-end-rule pathway
Biochem J, 343 Pt 1 (Pt 1), 199-207
DOI 10.1042/0264-6021:3430199, PubMed 10493930

Klingenberg O, Wiedlocha A, Olsnes S (1999)
Effects of mutations of a phosphorylation site in an exposed loop in acidic fibroblast growth factor
J Biol Chem, 274 (25), 18081-6
DOI 10.1074/jbc.274.25.18081, PubMed 10364261

Kolpakova E, Wiedłocha A, Stenmark H, Klingenberg O, Falnes PO, Olsnes S (1998)
Cloning of an intracellular protein that binds selectively to mitogenic acidic fibroblast growth factor
Biochem J, 336 ( Pt 1) (Pt 1), 213-22
DOI 10.1042/bj3360213, PubMed 9806903

Wesche J, Elliott JL, Falnes PO, Olsnes S, Collier RJ (1998)
Characterization of membrane translocation by anthrax protective antigen
Biochemistry, 37 (45), 15737-46
DOI 10.1021/bi981436i, PubMed 9843379

Zalecki P, Radzikowski C, Olsnes S, Wiedłocha A (1998)
Modulation by interleukin-2 of cellular response to fibroblast growth factor-1 in F69-3 fibrosarcoma cells
Exp Cell Res, 244 (1), 61-70
DOI 10.1006/excr.1998.4187, PubMed 9770349

Loukianov EV, Loukianova T, Wiedlocha A, Olsnes S (1998)
Variation in the proregion structure of heparin-binding EGF-like growth factor precursors
Gene, 212 (1), 1-4
DOI 10.1016/s0378-1119(98)00139-5, PubMed 9661657

Klingenberg O, Widlocha A, Rapak A, Muñoz R, Falnes P, Olsnes S (1998)
Inability of the acidic fibroblast growth factor mutant K132E to stimulate DNA synthesis after translocation into cells
J Biol Chem, 273 (18), 11164-72
DOI 10.1074/jbc.273.18.11164, PubMed 9556604

Falnes PO, Olsnes S (1998)
Modulation of the intracellular stability and toxicity of diphtheria toxin through degradation by the N-end rule pathway
EMBO J, 17 (2), 615-25
DOI 10.1093/emboj/17.2.615, PubMed 9430652

Olsnes S (1998)
Shiga and Shiga-like toxins
RECENT ADVANCES IN THE PATHOGENESIS OF GASTROINTESTINAL BACTERIAL INFECTIONS, 143-153

Loukianov E, Loukianova T, Wiedlocha A, Olsnes S (1997)
Expression of mRNA for a short form of heparin-binding EGF-like growth factor
Gene, 195 (1), 81-6
DOI 10.1016/s0378-1119(97)00161-3, PubMed 9300824

Muñoz R, Klingenberg O, Wiedłocha A, Rapak A, Falnes PO, Olsnes S (1997)
Effect of mutation of cytoplasmic receptor domain and of genistein on transport of acidic fibroblast growth factor into cells
Oncogene, 15 (5), 525-36
DOI 10.1038/sj.onc.1201226, PubMed 9247306

Polesskaya AN, Garred O, Olsnes S, Kozlov YV (1997)
Self-inhibition of N-glycosidase activity of shiga toxin
Mol. Biol., 31 (3), 441-447

Garred O, Dubinina E, Polesskaya A, Olsnes S, Kozlov J, Sandvig K (1997)
Role of the disulfide bond in Shiga toxin A-chain for toxin entry into cells
J Biol Chem, 272 (17), 11414-9
DOI 10.1074/jbc.272.17.11414, PubMed 9111051

Rapak A, Falnes PO, Olsnes S (1997)
Retrograde transport of mutant ricin to the endoplasmic reticulum with subsequent translocation to cytosol
Proc Natl Acad Sci U S A, 94 (8), 3783-8
DOI 10.1073/pnas.94.8.3783, PubMed 9108055

Lanzrein M, Falnes PO, Sand O, Olsnes S (1997)
Structure-function relationship of the ion channel formed by diphtheria toxin in Vero cell membranes
J Membr Biol, 156 (2), 141-8
DOI 10.1007/s002329900196, PubMed 9075645

Lemichez E, Bomsel M, Devilliers G, vanderSpek J, Murphy JR, Lukianov EV, Olsnes S, Boquet P (1997)
Membrane translocation of diphtheria toxin fragment A exploits early to late endosome trafficking machinery
Mol Microbiol, 23 (3), 445-57
DOI 10.1111/j.1365-2958.1997.tb02669.x, PubMed 9044279

Polesskaia AN, Garred O, Olsnes S, Kozlov IuV (1997)
[Self-inhibiting N-glycosidase activity of shigella toxin]
Mol Biol (Mosk), 31 (3), 528-35
PubMed 9297098

Waldum HL, Osmundsen H, Olsnes S, Sand O (1996)
[The Anders Jahre medical awarad 1996]
Tidsskr Nor Laegeforen, 116 (23), 2804-6
PubMed 8928170

Lanzrein M, Sand O, Olsnes S (1996)
GPI-anchored diphtheria toxin receptor allows membrane translocation of the toxin without detectable ion channel activity
EMBO J, 15 (4), 725-34
DOI 10.1002/j.1460-2075.1996.tb00408.x, PubMed 8631294

Klingenberg O, Olsnes S (1996)
Ability of methotrexate to inhibit translocation to the cytosol of dihydrofolate reductase fused to diphtheria toxin
Biochem J, 313 ( Pt 2) (Pt 2), 647-53
DOI 10.1042/bj3130647, PubMed 8573105

Wiedłocha A, Falnes PO, Rapak A, Muñoz R, Klingenberg O, Olsnes S (1996)
Stimulation of proliferation of a human osteosarcoma cell line by exogenous acidic fibroblast growth factor requires both activation of receptor tyrosine kinase and growth factor internalization
Mol Cell Biol, 16 (1), 270-80
DOI 10.1128/MCB.16.1.270, PubMed 8524304

Wiedłocha A, Falnes PO, Rapak A, Klingenberg O, Muñoz R, Olsnes S (1995)
Translocation of cytosol of exogenous, CAAX-tagged acidic fibroblast growth factor
J Biol Chem, 270 (51), 30680-5
DOI 10.1074/jbc.270.51.30680, PubMed 8530506

Falnes PO, Wiedłocha A, Rapak A, Olsnes S (1995)
Farnesylation of CaaX-tagged diphtheria toxin A-fragment as a measure of transfer to the cytosol
Biochemistry, 34 (35), 11152-9
DOI 10.1021/bi00035a021, PubMed 7669773

Falnes PO, Olsnes S (1995)
Cell-mediated reduction and incomplete membrane translocation of diphtheria toxin mutants with internal disulfides in the A fragment
J Biol Chem, 270 (35), 20787-93
DOI 10.1074/jbc.270.35.20787, PubMed 7657662

Lanzrein M, Garred O, Olsnes S, Sandvig K (1995)
Diphtheria toxin endocytosis and membrane translocation are dependent on the intact membrane-anchored receptor (HB-EGF precursor): studies on the cell-associated receptor cleaved by a metalloprotease in phorbol-ester-treated cells
Biochem J, 310 ( Pt 1) (Pt 1), 285-9
DOI 10.1042/bj3100285, PubMed 7646457

Valdizan EM, Loukianov EV, Olsnes S (1995)
Induction of toxin sensitivity in insect cells by infection with baculovirus encoding diphtheria toxin receptor
J Biol Chem, 270 (28), 16879-85
DOI 10.1074/jbc.270.28.16879, PubMed 7622504

Garred O, Dubinina E, Holm PK, Olsnes S, van Deurs B, Kozlov JV, Sandvig K (1995)
Role of processing and intracellular transport for optimal toxicity of Shiga toxin and toxin mutants
Exp Cell Res, 218 (1), 39-49
DOI 10.1006/excr.1995.1128, PubMed 7737376

Eriksen S, Olsnes S, Sandvig K, Sand O (1994)
Diphtheria toxin at low pH depolarizes the membrane, increases the membrane conductance and induces a new type of ion channel in Vero cells
EMBO J, 13 (19), 4433-9
DOI 10.1002/j.1460-2075.1994.tb06765.x, PubMed 7523112

Wiedłocha A, Falnes PO, Madshus IH, Sandvig K, Olsnes S (1994)
Dual mode of signal transduction by externally added acidic fibroblast growth factor
Cell, 76 (6), 1039-51
DOI 10.1016/0092-8674(94)90381-6, PubMed 7511061

Falnes PO, Choe S, Madshus IH, Wilson BA, Olsnes S (1994)
Inhibition of membrane translocation of diphtheria toxin A-fragment by internal disulfide bridges
J Biol Chem, 269 (11), 8402-7
PubMed 8132565

Esbensen QY, Falnes PO, Olsnes S, Madshus IH (1993)
Subcloning and characterization of the binding domain of fragment B of diphtheria toxin
Biochem J, 294 ( Pt 3) (Pt 3), 663-6
DOI 10.1042/bj2940663, PubMed 8379922

Ludt J, Sandvig K, Olsnes S (1993)
Rapid increase in pH set-point of the Na(+)-in-dependent chloride/bicarbonate antiporter in Vero cells exposed to heat shock
J Membr Biol, 134 (2), 143-53
DOI 10.1007/BF00232750, PubMed 8411117

Moskaug JO, Prydz K, Olsnes S (1993)
Rapid cellular removal of a membrane-inserted foreign polypeptide
Biochem J, 291 ( Pt 2) (Pt 2), 473-7
DOI 10.1042/bj2910473, PubMed 8484728

Melby EL, Jacobsen J, Olsnes S, Sandvig K (1993)
Entry of protein toxins in polarized epithelial cells
Cancer Res, 53 (8), 1755-60
PubMed 8467493

Aullo P, Giry M, Olsnes S, Popoff MR, Kocks C, Boquet P (1993)
A chimeric toxin to study the role of the 21 kDa GTP binding protein rho in the control of actin microfilament assembly
EMBO J, 12 (3), 921-31
DOI 10.1002/j.1460-2075.1993.tb05733.x, PubMed 8458345

Ariansen S, Afanasiev BN, Moskaug JO, Stenmark H, Madshus IH, Olsnes S (1993)
Membrane translocation of diphtheria toxin A-fragment: role of carboxy-terminal region
Biochemistry, 32 (1), 83-90
DOI 10.1021/bi00052a012, PubMed 8418864

Wiedlocha A, Madshus IH, Mach H, Middaugh CR, Olsnes S (1992)
Tight folding of acidic fibroblast growth factor prevents its translocation to the cytosol with diphtheria toxin as vector
EMBO J, 11 (13), 4835-42
DOI 10.1002/j.1460-2075.1992.tb05589.x, PubMed 1281450

Madshus IH, Olsnes S, Stenmark H (1992)
Membrane translocation of diphtheria toxin carrying passenger protein domains
Infect Immun, 60 (8), 3296-302
DOI 10.1128/iai.60.8.3296-3302.1992, PubMed 1639497

Falnes PO, Madshus IH, Sandvig K, Olsnes S (1992)
Replacement of negative by positive charges in the presumed membrane-inserted part of diphtheria toxin B fragment. Effect on membrane translocation and on formation of cation channels
J Biol Chem, 267 (17), 12284-90
PubMed 1376320

Stenmark H, Ariansen S, Afanasiev BN, Olsnes S (1992)
Interactions of diphtheria toxin B-fragment with cells. Role of amino- and carboxyl-terminal regions
J Biol Chem, 267 (13), 8957-62
PubMed 1374382

Stenmark H, Afanasiev BN, Ariansen S, Olsnes S (1992)
Association between diphtheria toxin A- and B-fragment and their fusion proteins
Biochem J, 281 ( Pt 3) (Pt 3), 619-25
DOI 10.1042/bj2810619, PubMed 1536643

Melby EL, Prydz K, Olsnes S, Sandvig K (1991)
Effect of monensin on ricin and fluid phase transport in polarized MDCK cells
J Cell Biochem, 47 (3), 251-60
DOI 10.1002/jcb.240470311, PubMed 1791187

Madshus IH, Stenmark H, Sandvig K, Olsnes S (1991)
Entry of diphtheria toxin-protein A chimeras into cells
J Biol Chem, 266 (26), 17446-53
PubMed 1894632

Stenmark H, Moskaug JO, Madshus IH, Sandvig K, Olsnes S (1991)
Peptides fused to the amino-terminal end of diphtheria toxin are translocated to the cytosol
J Cell Biol, 113 (5), 1025-32
DOI 10.1083/jcb.113.5.1025, PubMed 2040642

Stenmark H, Olsnes S, Madshus IH (1991)
Elimination of the disulphide bridge in fragment B of diphtheria toxin: effect on membrane insertion, channel formation, and ATP binding
Mol Microbiol, 5 (3), 595-606
DOI 10.1111/j.1365-2958.1991.tb00730.x, PubMed 1646374

Moskaug JO, Stenmark H, Olsnes S (1991)
Insertion of diphtheria toxin B-fragment into the plasma membrane at low pH. Characterization and topology of inserted regions
J Biol Chem, 266 (4), 2652-9
PubMed 1990012

Wiedłocha A, Sandvig K, Walzel H, Radzikowsky C, Olsnes S (1991)
Internalization and action of an immunotoxin containing mistletoe lectin A-chain
Cancer Res, 51 (3), 916-20
PubMed 1988131

Ludt J, Tønnessen TI, Sandvig K, Olsnes S (1991)
Evidence for involvement of protein kinase C in regulation of intracellular pH by Cl-/HCO-3 antiport
J Membr Biol, 119 (2), 179-86
DOI 10.1007/BF01871417, PubMed 2046087

Tønnessen TI, Sandvig K, Olsnes S (1990)
Role of Na(+)-H+ and Cl(-)-HCO3- antiports in the regulation of cytosolic pH near neutrality
Am J Physiol, 258 (6 Pt 1), C1117-26
DOI 10.1152/ajpcell.1990.258.6.C1117, PubMed 2163200

Tønnessen TI, Aas AT, Ludt J, Blomhoff HK, Olsnes S (1990)
Regulation of Na+/H+ and Cl-/HCO3- antiports in Vero cells
J Cell Physiol, 143 (1), 178-87
DOI 10.1002/jcp.1041430125, PubMed 2156872

Olsnes S, Moskaug JO, Stenmark H, Sandvig K (1990)
Translocation of diphtheria toxin to the cytosol and formation of cation selective channels
J Physiol (Paris), 84 (3), 191-6
PubMed 1705980

Hansen SH, Petersen OW, Sandvig K, Olsnes S, van Deurs B (1989)
Internalized ricin and the plasma membrane glycoprotein MAM-6 colocalize in the trans-Golgi network of T47D human breast carcinoma cells
Exp Cell Res, 185 (2), 373-86
DOI 10.1016/0014-4827(89)90307-8, PubMed 2689197

Tønnessen TI, Aas AT, Sandvig K, Olsnes S (1989)
Inhibition of chloride/bicarbonate antiports in monkey kidney cells (Vero) by non-steroidal anti-inflammatory drugs
Biochem Pharmacol, 38 (20), 3583-91
DOI 10.1016/0006-2952(89)90131-7, PubMed 2818647

McGill S, Stenmark H, Sandvig K, Olsnes S (1989)
Membrane interactions of diphtheria toxin analyzed using in vitro synthesized mutants
EMBO J, 8 (10), 2843-8
DOI 10.1002/j.1460-2075.1989.tb08431.x, PubMed 2684631

Stenmark H, McGill S, Olsnes S, Sandvig K (1989)
Permeabilization of the plasma membrane by deletion mutants of diphtheria toxin
EMBO J, 8 (10), 2849-53
DOI 10.1002/j.1460-2075.1989.tb08432.x, PubMed 2479538

Moskaug JO, Sletten K, Sandvig K, Olsnes S (1989)
Translocation of diphtheria toxin A-fragment to the cytosol. Role of the site of interfragment cleavage
J Biol Chem, 264 (26), 15709-13
PubMed 2768283

Olsnes S, Stenmark H, McGill S, Hovig E, Collier RJ, Sandvig K (1989)
Formation of active diphtheria toxin in vitro based on ligated fragments of cloned mutant genes
J Biol Chem, 264 (22), 12747-51
PubMed 2753882

Moskaug JO, Sandvig K, Olsnes S (1989)
Role of anions in low pH-induced translocation of diphtheria toxin
J Biol Chem, 264 (19), 11367-72
PubMed 2500440

Sandvig K, Olsnes S, Brown JE, Petersen OW, van Deurs B (1989)
Endocytosis from coated pits of Shiga toxin: a glycolipid-binding protein from Shigella dysenteriae 1
J Cell Biol, 108 (4), 1331-43
DOI 10.1083/jcb.108.4.1331, PubMed 2564398

Tønnessen TI, Aas AT, Sandvig K, Olsnes S (1989)
Effect of anti-inflammatory analgesic drugs on the regulation of cytosolic pH by anion antiport
J Pharmacol Exp Ther, 248 (3), 1197-206
PubMed 2703970

van Deurs B, Petersen OW, Sandvig K, Olsnes S (1989)
[Endocytosis, intracellular transport and sorting of proteins]
Nord Med, 104 (1), 9-11
PubMed 2911460

Stenmark H, Olsnes S, Sandvig K (1988)
Requirement of specific receptors for efficient translocation of diphtheria toxin A fragment across the plasma membrane
J Biol Chem, 263 (26), 13449-55
PubMed 3417666

Sandvig K, Olsnes S (1988)
Diphtheria toxin-induced channels in Vero cells selective for monovalent cations
J Biol Chem, 263 (25), 12352-9
PubMed 2457582

Reinertsen KV, Tønnessen TI, Jacobsen J, Sandvig K, Olsnes S (1988)
Role of chloride/bicarbonate antiport in the control of cytosolic pH. Cell-line differences in activity and regulation of antiport
J Biol Chem, 263 (23), 11117-25
PubMed 3403517

Moskaug JO, Sandvig K, Olsnes S (1988)
Low pH-induced release of diphtheria toxin A-fragment in Vero cells. Biochemical evidence for transfer to the cytosol
J Biol Chem, 263 (5), 2518-25
PubMed 3339019

van Deurs B, Sandvig K, Petersen OW, Olsnes S, Simons K, Griffiths G (1988)
Estimation of the amount of internalized ricin that reaches the trans-Golgi network
J Cell Biol, 106 (2), 253-67
DOI 10.1083/jcb.106.2.253, PubMed 2892843

Holtskog R, Sandvig K, Olsnes S (1988)
Characterization of a toxic lectin in Iscador, a mistletoe preparation with alleged cancerostatic properties
Oncology, 45 (3), 172-9
DOI 10.1159/000226557, PubMed 3368193

Sandvig K, Olsnes S, Petersen OW, van Deurs B (1988)
Inhibition of endocytosis from coated pits by acidification of the cytosol
J Cell Biochem, 36 (1), 73-81
DOI 10.1002/jcb.240360108, PubMed 2893802

Tønnessen TI, Ludt J, Sandvig K, Olsnes S (1987)
Bicarbonate/chloride antiport in Vero cells: I. Evidence for both sodium-linked and sodium-independent exchange
J Cell Physiol, 132 (2), 183-91
DOI 10.1002/jcp.1041320202, PubMed 3624314

Sandvig K, Olsnes S, Petersen OW, van Deurs B (1987)
Acidification of the cytosol inhibits endocytosis from coated pits
J Cell Biol, 105 (2), 679-89
DOI 10.1083/jcb.105.2.679, PubMed 2887575

Olsnes S, Ludt J, Tønnessen TI, Sandvig K (1987)
Bicarbonate/chloride antiport in Vero cells: II. Mechanisms for bicarbonate-dependent regulation of intracellular pH
J Cell Physiol, 132 (2), 192-202
DOI 10.1002/jcp.1041320203, PubMed 3624315

Moskaug JO, Sandvig K, Olsnes S (1987)
Cell-mediated reduction of the interfragment disulfide in nicked diphtheria toxin. A new system to study toxin entry at low pH
J Biol Chem, 262 (21), 10339-45
PubMed 3112141

van Deurs B, Petersen OW, Olsnes S, Sandvig K (1987)
Delivery of internalized ricin from endosomes to cisternal Golgi elements is a discontinuous, temperature-sensitive process
Exp Cell Res, 171 (1), 137-52
DOI 10.1016/0014-4827(87)90257-6, PubMed 3622628

Madshus IH, Olsnes S (1987)
Selective inhibition of sodium-linked and sodium-independent bicarbonate/chloride antiport in Vero cells
J Biol Chem, 262 (16), 7486-91
PubMed 3584123

Aarnes CM, Madshus IH, Guillemot JC, Sandvig K, Olsnes S (1987)
Formation and activity of covalent conjugates of poliovirus and ligands binding to cell surface structures
Exp Cell Res, 170 (2), 483-90
DOI 10.1016/0014-4827(87)90322-3, PubMed 3036553

Olsnes S, Tønnessen TI, Ludt J, Sandvig K (1987)
Effect of intracellular pH on the rate of chloride uptake and efflux in different mammalian cell lines
Biochemistry, 26 (10), 2778-85
DOI 10.1021/bi00384a019, PubMed 3606992

Madshus IH, Sandvig K, Olsnes S, van Deurs B (1987)
Effect of reduced endocytosis induced by hypotonic shock and potassium depletion on the infection of Hep 2 cells by picornaviruses
J Cell Physiol, 131 (1), 14-22
DOI 10.1002/jcp.1041310104, PubMed 3032992

Madshus IH, Tønnessen TI, Olsnes S, Sandvig K (1987)
Effect of potassium depletion of Hep 2 cells on intracellular pH and on chloride uptake by anion antiport
J Cell Physiol, 131 (1), 6-13
DOI 10.1002/jcp.1041310103, PubMed 3571337

Sandvig K, Tønnessen TI, Olsnes S (1986)
Ability of inhibitors of glycosylation and protein synthesis to sensitize cells to abrin, ricin, Shigella toxin, and Pseudomonas toxin
Cancer Res, 46 (12 Pt 1), 6418-22
PubMed 3096563

Sandvig K, Tønnessen TI, Sand O, Olsnes S (1986)
Requirement of a transmembrane pH gradient for the entry of diphtheria toxin into cells at low pH
J Biol Chem, 261 (25), 11639-44
PubMed 3745160

SANDVIG K, TONNESSEN TI, SAND O, OLSNES S (1986)
REQUIREMENT OF A TRANSMEMBRANE PH GRADIENT FOR THE ENTRY OF DIPHTHERIA-TOXIN INTO CELLS AT LOW PH
J. Biol. Chem., 261 (25), 1639-1644

Olsnes S, Tønnessen TI, Sandvig K (1986)
pH-regulated anion antiport in nucleated mammalian cells
J Cell Biol, 102 (3), 967-71
DOI 10.1083/jcb.102.3.967, PubMed 3949885

Olsnes S, Sandvig K (1986)
Interactions between diphtheria toxin entry and anion transport in Vero cells. I. Anion antiport in Vero cells
J Biol Chem, 261 (4), 1542-52
PubMed 3944100

Olsnes S, Carvajal E, Sandvig K (1986)
Interactions between diphtheria toxin entry and anion transport in vero cells. III. Effect on toxin binding and anion transport of tumor-promoting phorbol esters, vanadate, fluoride, and salicylate
J Biol Chem, 261 (4), 1562-9
PubMed 3632976

Olsnes S, Sandvig K (1986)
Interactions between diphtheria toxin entry and anion transport in Vero cells. II. Inhibition of anion antiport by diphtheria toxin
J Biol Chem, 261 (4), 1553-61
PubMed 3944101

Sandvig K, Olsnes S (1986)
Interactions between diphtheria toxin entry and anion transport in Vero cells. IV. Evidence that entry of diphtheria toxin is dependent on efficient anion transport
J Biol Chem, 261 (4), 1570-5
PubMed 2418015

van Deurs B, Tønnessen TI, Petersen OW, Sandvig K, Olsnes S (1986)
Routing of internalized ricin and ricin conjugates to the Golgi complex
J Cell Biol, 102 (1), 37-47
DOI 10.1083/jcb.102.1.37, PubMed 3001103

Stirpe F, Barbieri L, Abbondanza A, Falasca AI, Brown AN, Sandvig K, Olsnes S, Pihl A (1985)
Properties of volkensin, a toxic lectin from Adenia volkensii
J Biol Chem, 260 (27), 14589-95
PubMed 3932357

Olsnes S, Carvajal E, Sundan A, Sandvig K (1985)
Evidence that membrane phospholipids and protein are required for binding of diphtheria toxin in Vero cells
Biochim Biophys Acta, 846 (3), 334-41
DOI 10.1016/0167-4889(85)90003-5, PubMed 4041483

van Deurs B, Pedersen LR, Sundan A, Olsnes S, Sandvig K (1985)
Receptor-mediated endocytosis of a ricin-colloidal gold conjugate in vero cells. Intracellular routing to vacuolar and tubulo-vesicular portions of the endosomal system
Exp Cell Res, 159 (2), 287-304
DOI 10.1016/s0014-4827(85)80003-3, PubMed 2863159

Sandvig K, Sundan A, Olsnes S (1985)
Effect of potassium depletion of cells on their sensitivity to diphtheria toxin and pseudomonas toxin
J Cell Physiol, 124 (1), 54-60
DOI 10.1002/jcp.1041240110, PubMed 3930519

Sandvig K, Olsnes S (1985)
Effect of the chaotropic anions thiocyanate and perchlorate on the entry of ricin into Vero cells
Biochem J, 228 (2), 521-3
DOI 10.1042/bj2280521, PubMed 2990449

Guillemot JC, Sundan A, Olsnes S, Sandvig K (1985)
Entry of diphtheria toxin linked to concanavalin A into primate and murine cells
J Cell Physiol, 122 (2), 193-9
DOI 10.1002/jcp.1041220205, PubMed 3844014

OLSNES S, SANDVIG K, MADSHUS IH, SUNDAN A (1985)
ENTRY MECHANISMS OF PROTEIN TOXINS AND PICORNAVIRUSES
Biochem. Soc. Symp. (50), 171-191

STIRPE F, BARBIERI L, ABBONDANZA A, FALASCA AI, BROWN ANF, SANDVIG K, OLSNES S, PIHL A (1985)
PROPERTIES OF VOLKENSIN, A TOXIC LECTIN FROM ADENIA-VOLKENSII
J. Biol. Chem., 260 (27), 4589-4595

Madshus IH, Olsnes S, Sandvig K (1984)
Different pH requirements for entry of the two picornaviruses, human rhinovirus 2 and murine encephalomyocarditis virus
Virology, 139 (2), 346-57
DOI 10.1016/0042-6822(84)90380-5, PubMed 6097029

Sundan A, Sandvig K, Olsnes S (1984)
Effect of malignant transformation, retinoic acid, trifluoperazine, and N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W7) on the sensitivity of rodent cells to Pseudomonas toxin
Cancer Res, 44 (11), 4919-23
PubMed 6435858

Madshus IH, Olsnes S, Sandvig K (1984)
Requirements for entry of poliovirus RNA into cells at low pH
EMBO J, 3 (9), 1945-50
DOI 10.1002/j.1460-2075.1984.tb02074.x, PubMed 6092049

Sandvig K, Madshus IH, Olsnes S (1984)
Dimethyl sulphoxide protects cells against polypeptide toxins and poliovirus
Biochem J, 219 (3), 935-40
DOI 10.1042/bj2190935, PubMed 6331401

Sundan A, Sandvig K, Olsnes S (1984)
Calmodulin antagonists sensitize cells to pseudomonas toxin
J Cell Physiol, 119 (1), 15-22
DOI 10.1002/jcp.1041190104, PubMed 6707099

Sandvig K, Olsnes S (1984)
Anion requirement and effect of anion transport inhibitors on the response of vero cells to diphtheria toxin and modeccin
J Cell Physiol, 119 (1), 7-14
DOI 10.1002/jcp.1041190103, PubMed 6707104

Madshus IH, Olsnes S, Sandvig K (1984)
Mechanism of entry into the cytosol of poliovirus type 1: requirement for low pH
J Cell Biol, 98 (4), 1194-200
DOI 10.1083/jcb.98.4.1194, PubMed 6325467

Sandvig K, Sundan A, Olsnes S (1984)
Evidence that diphtheria toxin and modeccin enter the cytosol from different vesicular compartments
J Cell Biol, 98 (3), 963-70
DOI 10.1083/jcb.98.3.963, PubMed 6699094

Sandvig K, Olsnes S (1984)
Receptor-mediated entry of protein toxins into cells
Acta Histochem Suppl, 29, 79-94
PubMed 6144140

Sundan A, Sandvig K, Olsnes S (1983)
Preparation and properties of a hybrid toxin of modeccin A-chain and ricin B-chain
Biochim Biophys Acta, 761 (3), 296-302
DOI 10.1016/0304-4165(83)90080-6, PubMed 6652111

Sundan A, Sandvig K, Olsnes S (1983)
Dansylcadaverine eliminates calmodulin stimulation of phosphodiesterase
Biochem Biophys Res Commun, 117 (2), 562-7
DOI 10.1016/0006-291x(83)91237-8, PubMed 6318763

Eiklid K, Olsnes S (1983)
Entry of Shigella dysenteriae toxin into HeLa cells
Infect Immun, 42 (2), 771-7
DOI 10.1128/iai.42.2.771-777.1983, PubMed 6358031

Eiklid K, Olsnes S (1983)
Animal toxicity of Shigella dysenteriae cytotoxin: evidence that the neurotoxic, enterotoxic, and cytotoxic activities are due to one toxin
J Immunol, 130 (1), 380-4
PubMed 6336624

Olsnes S, Stirpe F, Sandvig K, Pihl A (1982)
Isolation and characterization of viscumin, a toxic lectin from Viscum album L. (mistletoe)
J Biol Chem, 257 (22), 13263-70
PubMed 7142144

Stirpe F, Sandvig K, Olsnes S, Pihl A (1982)
Action of viscumin, a toxic lectin from mistletoe, on cells in culture
J Biol Chem, 257 (22), 13271-7
PubMed 7142145

Sundan A, Olsnes S, Sandvig K, Pihl A (1982)
Preparation and properties of chimeric toxins prepared from the constituent polypeptides of diphtheria toxin and ricin. Evidence for entry of ricin A-chain via the diphtheria toxin pathway
J Biol Chem, 257 (16), 9733-9
PubMed 7107588

Sandvig K, Olsnes S (1982)
Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. II. Effect of pH, metabolic inhibitors, and ionophores and evidence for toxin penetration from endocytotic vesicles
J Biol Chem, 257 (13), 7504-13
PubMed 7085634

Sandvig K, Olsnes S (1982)
Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. I. Requirement for calcium
J Biol Chem, 257 (13), 7495-503
PubMed 6806276

Olsnes S, Haylett T, Sandvig K (1982)
The toxic lectin modeccin
Methods Enzymol, 83, 357-62
DOI 10.1016/0076-6879(82)83030-9, PubMed 6178935

Sandvig K, Olsnes S (1981)
Rapid entry of nicked diphtheria toxin into cells at low pH. Characterization of the entry process and effects of low pH on the toxin molecule
J Biol Chem, 256 (17), 9068-76
PubMed 7263699

Godal A, Olsnes S, Pihl A (1981)
Radioimmunoassays of abrin and ricin in blood
J Toxicol Environ Health, 8 (3), 409-17
DOI 10.1080/15287398109530079, PubMed 7345165

Reisbig R, Olsnes S, Eiklid K (1981)
The cytotoxic activity of Shigella toxin. Evidence for catalytic inactivation of the 60 S ribosomal subunit
J Biol Chem, 256 (16), 8739-44
PubMed 6894922

Olsnes S, Reisbig R, Eiklid K (1981)
Subunit structure of Shigella cytotoxin
J Biol Chem, 256 (16), 8732-8
PubMed 7021550

Sandvig K, Olsnes S (1981)
Effects of retinoids and phorbol esters on the sensitivity of different cell lines to the polypeptide toxins modeccin, abrin, ricin and diphtheria toxin
Biochem J, 194 (3), 821-7
DOI 10.1042/bj1940821, PubMed 7306026

Tveit KM, Fodstad O, Olsnes S, Pihl A (1980)
In vitro sensitivity of human melanoma xenografts to cytotoxic drugs. Correlation with in vivo chemosensitivity
Int J Cancer, 26 (6), 717-22
DOI 10.1002/ijc.2910260604, PubMed 7216540

Gonatas J, Stieber A, Olsnes S, Gonatas NK (1980)
Pathways involved in fluid phase and adsorptive endocytosis in neuroblastoma
J Cell Biol, 87 (3 Pt 1), 579-88
DOI 10.1083/jcb.87.3.579, PubMed 7462317

Stirpe F, Olsnes S, Pihl A (1980)
Gelonin, a new inhibitor of protein synthesis, nontoxic to intact cells. Isolation, characterization, and preparation of cytotoxic complexes with concanavalin A
J Biol Chem, 255 (14), 6947-53
PubMed 7391060

Tveit KM, Fodstad O, Johannessen JV, Olsnes S (1980)
A human melanoma cell line established from xenograft in athymic mice
Br J Cancer, 41 (5), 724-33
DOI 10.1038/bjc.1980.134, PubMed 7426299

Eiklid K, Olsnes S, Pihl A (1980)
Entry of lethal doses of abrin, ricin and modeccin into the cytosol of HeLa cells
Exp Cell Res, 126 (2), 321-6
DOI 10.1016/0014-4827(80)90270-0, PubMed 7363949

Tveit KM, Fodstad O, Brøgger A, Olsnes S (1980)
Human embryonal carcinoma grown in athymic mice and in vitro
Cancer Res, 40 (3), 949-53
PubMed 7471109

Olsnes S, Eiklid K (1980)
Isolation and characterization of Shigella shigae cytotoxin
J Biol Chem, 255 (1), 284-9
PubMed 7350160

Eiklid K, Olsnes S (1980)
Interaction of Shigella shigae cytotoxin with receptors on sensitive and insensitive cells
J Recept Res, 1 (2), 199-213
DOI 10.3109/10799898009044098, PubMed 6895387

Sandvig K, Olsnes S, Pihl A (1979)
Inhibitory effect of ammonium chloride and chloroquine on the entry of the toxic lectin modeccin into HeLa cells
Biochem Biophys Res Commun, 90 (2), 648-55
DOI 10.1016/0006-291x(79)91284-1, PubMed 508328

Sandvig K, Olsnes S (1979)
Effect of temperature on the uptake, excretion and degradation of abrin and ricin by HeLa cells
Exp Cell Res, 121 (1), 15-25
DOI 10.1016/0014-4827(79)90439-7, PubMed 446525

Abraham AK, Olsnes S, Pihl A (1979)
Fidelity of protein synthesis in vitro is increased in the presence of spermidine
FEBS Lett, 101 (1), 93-6
DOI 10.1016/0014-5793(79)81302-2, PubMed 446744

Olsnes S, Abraham AK (1979)
Elongation-factor-2-induced sensitization of ribosomes to modeccin. Evidence for specific binding of elongation factor 2 to ribosomes in the absence of nucleotides
Eur J Biochem, 93 (3), 447-52
DOI 10.1111/j.1432-1033.1979.tb12842.x, PubMed 421687

Olsnes S, Tveit KM (1978)
[Teratocarcinoma as a model system in studies of malignancy and differentiation]
Tidsskr Nor Laegeforen, 98 (22), 998-1001
PubMed 684708

Olsnes S, Haylett T, Refsnes K (1978)
Purification and characterization of the highly toxic lectin modeccin
J Biol Chem, 253 (14), 5069-73
PubMed 97288

Olsnes S, Refsnes K (1978)
On the mechanism of toxin resistance in cell variants resistant to abrin and ricin
Eur J Biochem, 88 (1), 7-15
DOI 10.1111/j.1432-1033.1978.tb12417.x, PubMed 566668

Sandvig K, Olsnes S, Pihl A (1978)
Interactions between abrus lectins and Sephadex particles possessing immobilized desialylated fetuin. Model studies of the interaction of lectins with cell surface receptors
Eur J Biochem, 88 (1), 307-13
DOI 10.1111/j.1432-1033.1978.tb12451.x, PubMed 78847

Sandvig K, Olsnes S, Pihl A (1978)
Chemical modifications of the toxic lectins abrin and ricin
Eur J Biochem, 84 (2), 323-31
DOI 10.1111/j.1432-1033.1978.tb12171.x, PubMed 639792

Sandvig K, Olsnes S, Pihl A (1978)
Binding, uptake and degradation of the toxic proteins abrin and ricin by toxin-resistant cell variants
Eur J Biochem, 82 (1), 13-23
DOI 10.1111/j.1432-1033.1978.tb11992.x, PubMed 620666

Olsnes S, Sandvig K, Eiklid K, Pihl A (1978)
Properties and action mechanism of the toxic lectin modeccin: interaction with cell lines resistant to modeccin, abrin, and ricin
J Supramol Struct, 9 (1), 15-25
DOI 10.1002/jss.400090103, PubMed 732310

Olsnes S (1978)
Toxic and nontoxic lectins from Abrus precatorius
Methods Enzymol, 50, 323-30
DOI 10.1016/0076-6879(78)50036-0, PubMed 661585

OLSNES S, PIHL A (1978)
ABRIN AND RICIN-2 TOXIC LECTINS
Trends Biochem.Sci., 3 (1), 7-10
DOI 10.1016/S0968-0004(78)92494-5

Olsnes S (1978)
Ricin and ricinus agglutinin, toxic lectins from castor bean
Methods Enzymol, 50, 330-5
DOI 10.1016/0076-6879(78)50037-2, PubMed 661586

Refsnes K, Haylett T, Sandvig K, Olsnes S (1977)
Modeccin--a plant toxin inhibiting protein synthesis
Biochem Biophys Res Commun, 79 (4), 1176-83
DOI 10.1016/0006-291x(77)91130-5, PubMed 603653

Fodstad O, Olsnes S, Pihl A (1977)
Inhibitory effect of abrin and ricin on the growth of transplantable murine tumors and of abrin on human cancers in nude mice
Cancer Res, 37 (12), 4559-67
PubMed 922739

Skorve J, Abraham AK, Olsnes S, Pihl A (1977)
Effect of abrin on peptide chain initiation
Eur J Biochem, 79 (2), 559-64
DOI 10.1111/j.1432-1033.1977.tb11840.x, PubMed 243461

Fodstad O, Olsnes S (1977)
Studies on the accessability of ribosomes to inactivation by the toxic lectins abrin and ricin
Eur J Biochem, 74 (2), 209-15
DOI 10.1111/j.1432-1033.1977.tb11383.x, PubMed 856578

Fodstad O, Olsnes S, Pihl A (1976)
Toxicity, distribution and elimination of the cancerostatic lectins abrin and ricin after parenteral injection into mice
Br J Cancer, 34 (4), 418-25
DOI 10.1038/bjc.1976.187, PubMed 974006

Sandvig K, Olsnes S, Pihl A (1976)
Kinetics of binding of the toxic lectins abrin and ricin to surface receptors of human cells
J Biol Chem, 251 (13), 3977-84
PubMed 6468

Olsnes S, Sandvig K, Refsnes K, Pihl A (1976)
Rates of different steps involved in the inhibition of protein synthesis by the toxic lectins abrin and ricin
J Biol Chem, 251 (13), 3985-92
PubMed 932017

Fernandez-Puentes C, Benson S, Olsnes S, Pihl A (1976)
Protective effect of elongation factor 2 on the inactivation of ribosomes by the toxic lectins abrin and ricin
Eur J Biochem, 64 (2), 437-43
DOI 10.1111/j.1432-1033.1976.tb10320.x, PubMed 1278169

OLSNES S (1976)
ABRIN AND RICIN - STRUCTURE AND MECHANISM OF ACTION OF 2 TOXIC LECTINS
Bull. Inst. Pasteur, 74 (1), 85-99

Olsnes S, Fernandez-Puentes C, Carrasco L, Vazquez D (1975)
Ribosome inactivation by the toxic lectins abrin and ricin. Kinetics of the enzymic activity of the toxin A-chains
Eur J Biochem, 60 (1), 281-8
DOI 10.1111/j.1432-1033.1975.tb21001.x, PubMed 1204642

Benson S, Olsnes S, Pihl A, Skorve J, Abraham AK (1975)
On the mechanism of protein-synthesis inhibition by abrin and ricin. Inhibition of the GTP-hydrolysis site on the 60-S ribosomal subunit
Eur J Biochem, 59 (2), 573-80
DOI 10.1111/j.1432-1033.1975.tb02484.x, PubMed 128455

Closs O, Saltvedt E, Olsnes S (1975)
Stimulation of human lymphocytes by galactose-specific abrus and ricinus lectins
J Immunol, 115 (4), 1045-8
PubMed 1176765

Kozlov JV, Olsnes S, Brogger A, Pihl A (1975)
Cleavage of adenovirus-5 DNA by an endonuclease from Haemophilus parainfluenzae
FEBS Lett, 57 (2), 153-7
DOI 10.1016/0014-5793(75)80705-8, PubMed 1175785

Olsnes S, Refsnes K, Christensen TB, Pihl A (1975)
Studies on the structure and properties of the lectins from Abrus precatorius and Ricinus communis
Biochim Biophys Acta, 405 (1), 1-10
DOI 10.1016/0005-2795(75)90308-6, PubMed 1174560

Olsnes S, Saltvedt E (1975)
Conformation-dependent antigenic determinants in the toxic lectin ricin
J Immunol, 114 (6), 1743-8
PubMed 47877

HARBOE M, SALTVEDT E, CLOSS O, OLSNES S (1975)
INTERACTIONS BETWEEN RICINUS AGGLUTININ AND HUMAN PLASMA-PROTEINS
Scand. J. Immunol. (2), 125-134

Saltvedt E, Harboe M, Følling I, Olsnes S (1975)
Interactions between ricinus agglutinin and human IgM and IgG
Scand J Immunol, 4 (3), 287-94
DOI 10.1111/j.1365-3083.1975.tb02628.x, PubMed 1080291

Olsnes S, Pihl A (1974)
Clinical significance of estrogen receptors in human breast cancer
Biomedicine, 20 (6), 377-83
PubMed 4376029

Pappenheimer AM, Olsnes S, Harper AA (1974)
Lectins from Abrus precatorius and Ricinus communis. I. Immunochemical relationships between toxins and agglutinins
J Immunol, 113 (3), 835-41
PubMed 4213214

Olsnes S, Pappenheimer AM, Meren R (1974)
Lectins from Abrus precatorius and Ricinus communis. II. Hybrid toxins and their interaction with chain-specific antibodies
J Immunol, 113 (3), 842-7
PubMed 4414071

Olsnes S, Refsnes K, Pihl A (1974)
Mechanism of action of the toxic lectins abrin and ricin
Nature, 249 (458), 627-31
DOI 10.1038/249627a0, PubMed 4857870

Refsnes K, Olsnes S, Pihl A (1974)
On the toxic proteins abrin and ricin. Studies of their binding to and entry into Ehrlich ascites cells
J Biol Chem, 249 (11), 3557-62
PubMed 4208663

Olsnes S, Saltvedt E, Pihl A (1974)
Isolation and comparison of galactose-binding lectins from Abrus precatorius and Ricinus communis
J Biol Chem, 249 (3), 803-10
PubMed 4811904

REFSNES K, OLSNES S, PIHL A (1974)
TOXIC PROTEINS ABRIN AND RICIN - STUDIES OF THEIR BINDING TO AND ENTRY INTO EHRLICH ASCITES-CELLS
J. Biol. Chem., 249 (11), 3557-3562

Olsnes S, Pihl A (1973)
Different biological properties of the two constituent peptide chains of ricin, a toxic protein inhibiting protein synthesis
Biochemistry, 12 (16), 3121-6
DOI 10.1021/bi00740a028, PubMed 4730499

Olsnes S, Heiberg R, Pihl A (1973)
Inactivation of eucaryotic ribosomes by the toxic plant proteins abrin and ricin
Mol Biol Rep, 1 (1), 15-20
DOI 10.1007/BF00357400, PubMed 24197425

Spaeren U, Olsnes S, Brennhovd I, Efskind J, Pihl A (1973)
Content of estrogen receptors in human breast cancer
Eur J Cancer (1965), 9 (5), 353-7
DOI 10.1016/0014-2964(73)90050-9, PubMed 4355726

Olsnes S, Pihl A (1973)
Isolation and properties of abrin: a toxic protein inhibiting protein synthesis. Evidence for different biological functions of its two constituent-peptide chains
Eur J Biochem, 35 (1), 179-85
DOI 10.1111/j.1432-1033.1973.tb02823.x, PubMed 4123356

Olsnes S (1973)
[Diphtheria toxin--a specific inhibitor of protein synthesis]
Tidsskr Nor Laegeforen, 93 (4), 223-7
PubMed 4691026

Lukanidin EM, Olsnes S, Pihl A (1972)
Antigenic difference between informofers and protein bound to polyribosomal mRNA from rat liver
Nat New Biol, 240 (98), 90-2
DOI 10.1038/newbio240090a0, PubMed 4117892

Olsnes S, Pihl A (1972)
Treatment of abrin and ricin with -mercaptoethanol opposite effects on their toxicity in mice and their ability to inhibit protein synthesis in a cell-free system
FEBS Lett, 28 (1), 48-50
DOI 10.1016/0014-5793(72)80674-4, PubMed 4646874

Olsnes S (1972)
Toxic proteins inhibiting protein synthesis
Naturwissenschaften, 59 (11), 497-502
DOI 10.1007/BF00609814, PubMed 4657651

Olsnes S, Spaeren U, Heiberg R, Pihl A (1972)
Protein synthesis in the presence of non-ionic detergents in a cell-free system from rabbit reticulocytes
Biochem J, 130 (1), 297-9
DOI 10.1042/bj1300297, PubMed 4655435

Heiberg R, Spaeren U, Olsnes S, Pihl A (1972)
Binding of rat liver ribosomes to nuclear complementary RNA
Biochim Biophys Acta, 281 (2), 270-6
DOI 10.1016/0005-2787(72)90179-7, PubMed 4629425

Olsnes S, Pihl A (1972)
Inhibition of peptide chain elongation
Nature, 238 (5365), 459-61
DOI 10.1038/238459a0, PubMed 4561855

Spaeren U, Olsnes S, Pihl A (1972)
Translation of mouse globin mRNA by isolated ribosomal subunits from rabbit reticulocytes
Biochim Biophys Acta, 272 (4), 663-6
DOI 10.1016/0005-2787(72)90525-4, PubMed 5050924

Olsnes S, Heiberg R, Pihl A (1972)
Deoxycholate-induced release of monosomes from rat liver polyribosomes
Biochim Biophys Acta, 272 (1), 75-80
DOI 10.1016/0005-2787(72)90035-4, PubMed 5043716

Olsnes S, Pihl A (1972)
Ricin - a potent inhibitor of protein synthesis
FEBS Lett, 20 (3), 327-329
DOI 10.1016/0014-5793(72)80098-x, PubMed 11946449

Olsnes S, Pihl A (1972)
Possible function of the protein bound to nuclear complementary RNA
FEBS Lett, 20 (2), 181-183
DOI 10.1016/0014-5793(72)80788-9, PubMed 11946410

Olsnes S (1971)
Further studies on the protein bound to the messenger RNA in mammalian polysomes
Eur J Biochem, 23 (3), 557-63
DOI 10.1111/j.1432-1033.1971.tb01654.x, PubMed 5003111

Olsnes S (1971)
Evidence that protein is bound to the rapidly labelled RNA in polyribosomes in vivo
Eur J Biochem, 23 (2), 248-52
DOI 10.1111/j.1432-1033.1971.tb01615.x, PubMed 5003205

Heiberg R, Olsnes S, Pihl A (1971)
On the mechanism of the inhibiting effect of aurin tricarboxylic acid on the binding of ribosomes to ribonucleic acids
FEBS Lett, 18 (1), 169-171
DOI 10.1016/0014-5793(71)80436-2, PubMed 11946112

Olsnes S (1971)
The isolation of polysomes from rat liver. Contamination by membrane proteins with high affinity to ribosomes
Biochim Biophys Acta, 232 (4), 705-16
PubMed 5556851

Olsnes S (1971)
Characterization of the complex containing rapidly labelled RNA in EDTA-treated polyribosomes from rat liver
Eur J Biochem, 18 (2), 242-51
DOI 10.1111/j.1432-1033.1971.tb01237.x, PubMed 5541508

Olsnes S (1970)
Characterization of protein bound to rapidly-labelled RNA in polyribosomes from rat liver
Eur J Biochem, 15 (3), 464-71
DOI 10.1111/j.1432-1033.1970.tb01029.x, PubMed 4989503

Olsnes S (1970)
The isolation of polysomes from rat liver. Contamination of polysomes by ribonucleoprotein of nuclear origin
Biochim Biophys Acta, 213 (1), 149-58
DOI 10.1016/0005-2787(70)90016-x, PubMed 4992322

Olsnes S (1970)
Removal of structural proteins from ribosomes by treatment with sodium deoxycholate in the presence of EDTA
FEBS Lett, 7 (3), 211-213
DOI 10.1016/0014-5793(70)80162-4, PubMed 11947473

Olsnes S, Hauge JG (1968)
Amino acid control of RNA synthesis in T4-infected Escherichia coli
Eur J Biochem, 7 (1), 128-36
DOI 10.1111/j.1432-1033.1968.tb19583.x, PubMed 4884582

Review articles

Haugsten EM, Wiedlocha A, Olsnes S, Wesche J (2010)
Roles of fibroblast growth factor receptors in carcinogenesis
Mol Cancer Res, 8 (11), 1439-52
DOI 10.1158/1541-7786.MCR-10-0168, PubMed 21047773

Høiseth G, Olsnes S (2005)
[Ricin--a therapeutic agent and a biological weapon]
Tidsskr Nor Laegeforen, 125 (18), 2477-9
PubMed 16186864

Olsnes S (2004)
The history of ricin, abrin and related toxins
Toxicon, 44 (4), 361-70
DOI 10.1016/j.toxicon.2004.05.003, PubMed 15302520

Johnson HM, Subramaniam PS, Olsnes S, Jans DA (2004)
Trafficking and signaling pathways of nuclear localizing protein ligands and their receptors
Bioessays, 26 (9), 993-1004
DOI 10.1002/bies.20086, PubMed 15351969

Olsnes S, Klingenberg O, Wiedłocha A (2003)
Transport of exogenous growth factors and cytokines to the cytosol and to the nucleus
Physiol Rev, 83 (1), 163-82
DOI 10.1152/physrev.00021.2002, PubMed 12506129

Klingenberg O, Wiedocha A, Citores L, Olsnes S (2000)
Requirement of phosphatidylinositol 3-kinase activity for translocation of exogenous aFGF to the cytosol and nucleus
J Biol Chem, 275 (16), 11972-80
DOI 10.1074/jbc.275.16.11972, PubMed 10766827

Olsnes S, van Deurs B, Sandvig K (1993)
Protein toxins acting on intracellular targets: cellular uptake and translocation to the cytosol
Med Microbiol Immunol, 182 (2), 51-61
DOI 10.1007/BF00189373, PubMed 8392658

O'Brien AD, Tesh VL, Donohue-Rolfe A, Jackson MP, Olsnes S, Sandvig K, Lindberg AA, Keusch GT (1992)
Shiga toxin: biochemistry, genetics, mode of action, and role in pathogenesis
Curr Top Microbiol Immunol, 180, 65-94
DOI 10.1007/978-3-642-77238-2_4, PubMed 1324134

Olsnes S, Frankel AE (1992)
Genetically engineered toxins in perspective
Targeted Diagn Ther, 7, 465-77
PubMed 1633307

Olsnes S, Kozlov JV, van Deurs B, Sandvig K (1991)
Bacterial protein toxins acting on intracellular targets
Semin Cell Biol, 2 (1), 7-14
PubMed 1954345

Olsnes S, Stenmark H, Moskaug JO, McGill S, Madshus IH, Sandvig K (1990)
Protein toxins with intracellular targets
Microb Pathog, 8 (3), 163-8
DOI 10.1016/0882-4010(90)90043-p, PubMed 1696341

Olsnes S, Sandvig K, Petersen OW, van Deurs B (1989)
Immunotoxins--entry into cells and mechanisms of action
Immunol Today, 10 (9), 291-5
PubMed 2686677

van Deurs B, Petersen OW, Olsnes S, Sandvig K (1989)
The ways of endocytosis
Int Rev Cytol, 117, 131-77
DOI 10.1016/s0074-7696(08)61336-4, PubMed 2573583

Sandvig K, Olsnes S, Petersen OW, Van Deurs B (1989)
Control of coated-pit function by cytoplasmic pH
Methods Cell Biol, 32, 365-82
DOI 10.1016/s0091-679x(08)61181-4, PubMed 2575206

Olsnes S, Moskaug JO, Stenmark H, Sandvig K (1988)
Diphtheria toxin entry: protein translocation in the reverse direction
Trends Biochem Sci, 13 (9), 348-51
DOI 10.1016/0968-0004(88)90105-3, PubMed 3072713

Olsnes S, Sandvig K (1988)
How protein toxins enter and kill cells
Cancer Treat Res, 37, 39-73
DOI 10.1007/978-1-4613-1083-9_4, PubMed 2908634

Olsnes S, Sandvig K, Madshus IH, Sundan A (1985)
Entry mechanisms of protein toxins and picornaviruses
Biochem Soc Symp, 50, 171-91
PubMed 3915869

Olsnes S, Pihl A (1981)
Chimeric toxins
Pharmacol Ther, 15 (3), 355-81
DOI 10.1016/0163-7258(81)90050-4, PubMed 7345440

Olsnes S (1973)
[Gene activation and mRNA synthesis in higher organisms]
Tidsskr Nor Laegeforen, 93 (16), 1230-5
PubMed 4356591

Other articles

Olsnes S, Wesche J (2001)
Microbiology. Fighting anthrax with a mutant toxin
Science, 292 (5517), 647-8
DOI 10.1126/science.1060857, PubMed 11330322

Olsnes S, Falnes PO (2000)
Probing pores with peptide plugs. Topology of membrane-inserted diphtheria toxin
J Gen Physiol, 115 (4), 417-20
DOI 10.1085/jgp.115.4.417, PubMed 10736309

ERIKSEN S, SAND O, LANZREIN M, SANDVIG K, OLSNES S (1995)
CELL PENETRATION OF BACTERIAL PROTEIN TOXINS - RESPONSE
Trends Microbiol., 3 (5), 167-168
DOI 10.1016/S0966-842X(00)88912-X

Loukianov EV, Olsnes S (1993)
New cloning opportunities with the use of noncomplementary SfiI adaptors
Biotechniques, 15 (6), 980-2
PubMed 8292350

OLSNES S, STENMARK H, MCGILL S, HOVIG E, COLLIER RJ, SANDVIG K (1989)
FORMATION OF ACTIVE DIPHTHERIA-TOXIN INVITRO BASED ON LIGATED FRAGMENTS OF CLONED MUTANT-GENES
J. Biol. Chem., 264 (22), 12749-12751

Olsnes S (1987)
Closing in on ricin action
Nature, 328 (6130), 474-5
DOI 10.1038/328474b0, PubMed 3614350

Madshus IH, Sandvig K, Olsnes S (1985)
Tumor-promoting phorbol esters and vanadate alter the sensitivity of HeLa S3 cells to poliovirus type 1
Exp Cell Res, 160 (1), 240-4
DOI 10.1016/0014-4827(85)90253-8, PubMed 2995095

Olsnes S (1981)
Directing toxins to cancer cells
Nature, 290 (5802), 84
DOI 10.1038/290084a0, PubMed 7207602

Sandvig K, Olsnes S (1980)
Diphtheria toxin entry into cells is facilitated by low pH
J Cell Biol, 87 (3 Pt 1), 828-32
DOI 10.1083/jcb.87.3.828, PubMed 7462324

Book chapters

Nilsen T, Skjerpen CS, Olsnes S (2006)
Peroxisomal Targeting as a Tool to Assess Protein-Protein-Interactions
In Cell biology: A laboratory handbook (Celis JE, ed.), Elsevier Science, Amsterdam, 1, 275-278
PublikaID 31

Theses

Olsnes S (1971)
Studies on the complex of messenger-RNA and protein in mammalian cells: a comparative study between the complex of complementary RNA and protein in the cell nucleus and the ribonucleoproteincontaining rapidly labelled RNA in polyribosomes
Universitetsforlaget, [Oslo], 1 b. (flere pag.)
BIBSYS 931318157

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