Publications by Therese Sørlie
97 publications found
Original articles
Rapid assessment of 3-dimensional intra-tumor heterogeneity through cycling temperature capillary electrophoresis
BMC Res Notes, 16 (1), 167
DOI 10.1186/s13104-023-06437-5, PubMed 37568187
Liver X receptors induce antiproliferative effects in basal-like breast cancer
Mol Oncol, 17 (10), 2041-2055
DOI 10.1002/1878-0261.13476, PubMed 37341140
Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer
Cancer Discov, 12 (12), 2930-2953
DOI 10.1158/2159-8290.CD-21-0865, PubMed 36108220
RNA sequencing-based single sample predictors of molecular subtype and risk of recurrence for clinical assessment of early-stage breast cancer
NPJ Breast Cancer, 8 (1), 94
DOI 10.1038/s41523-022-00465-3, PubMed 35974007
Comparative analysis of the molecular subtype landscape in canine and human mammary gland tumors
J Mammary Gland Biol Neoplasia, 27 (2), 171-183
DOI 10.1007/s10911-022-09523-9, PubMed 35932380
Sample Preparation Approach Influences PAM50 Risk of Recurrence Score in Early Breast Cancer
Cancers (Basel), 13 (23)
DOI 10.3390/cancers13236118, PubMed 34885228
Best Practices for Spatial Profiling for Breast Cancer Research with the GeoMx® Digital Spatial Profiler
Cancers (Basel), 13 (17)
DOI 10.3390/cancers13174456, PubMed 34503266
Multi-Omics Marker Analysis Enables Early Prediction of Breast Tumor Progression
Front Genet, 12, 670749
DOI 10.3389/fgene.2021.670749, PubMed 34149812
Can breast cancer be stopped? Modifiable risk factors of breast cancer among women with a prior benign or premalignant lesion
Int J Cancer, 149 (6), 1247-1256
DOI 10.1002/ijc.33680, PubMed 33990967
AXL Is a Driver of Stemness in Normal Mammary Gland and Breast Cancer
iScience, 23 (11), 101649
DOI 10.1016/j.isci.2020.101649, PubMed 33103086
Contrasting DCIS and invasive breast cancer by subtype suggests basal-like DCIS as distinct lesions
NPJ Breast Cancer, 6, 26
DOI 10.1038/s41523-020-0167-x, PubMed 32577501
Comparable cancer-relevant mutation profiles in synchronous ductal carcinoma in situ and invasive breast cancer
Cancer Rep (Hoboken), 3 (3), e1248
DOI 10.1002/cnr2.1248, PubMed 32671987
Re-definition of claudin-low as a breast cancer phenotype
Nat Commun, 11 (1), 1787
DOI 10.1038/s41467-020-15574-5, PubMed 32286297
The expression of the long NEAT1_2 isoform is associated with human epidermal growth factor receptor 2-positive breast cancers
Sci Rep, 10 (1), 1277
DOI 10.1038/s41598-020-57759-4, PubMed 31992741
An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvironment
Nat Commun, 10 (1), 5499
DOI 10.1038/s41467-019-13329-5, PubMed 31796750
A Bayesian two-way latent structure model for genomic data integration reveals few pan-genomic cluster subtypes in a breast cancer cohort
Bioinformatics, 35 (23), 4886-4897
DOI 10.1093/bioinformatics/btz381, PubMed 31077301
Claudin-low-like mouse mammary tumors show distinct transcriptomic patterns uncoupled from genomic drivers
Breast Cancer Res, 21 (1), 85
DOI 10.1186/s13058-019-1170-8, PubMed 31366361
GLI1-induced mammary gland tumours are transplantable and maintain major molecular features
Int J Cancer, 146 (4), 1125-1138
DOI 10.1002/ijc.32522, PubMed 31219615
A Longitudinal Study of the Association between Mammographic Density and Gene Expression in Normal Breast Tissue
J Mammary Gland Biol Neoplasia, 24 (2), 163-175
DOI 10.1007/s10911-018-09423-x, PubMed 30613869
The tankyrase inhibitor G007-LK inhibits small intestine LGR5+ stem cell proliferation without altering tissue morphology
Biol Res, 51 (1), 3
DOI 10.1186/s40659-017-0151-6, PubMed 29316982
Intrinsic subtypes and benefit from postmastectomy radiotherapy in node-positive premenopausal breast cancer patients who received adjuvant chemotherapy - results from two independent randomized trials
Acta Oncol, 57 (1), 38-43
DOI 10.1080/0284186X.2017.1401735, PubMed 29172851
Prognostic value of PAM50 and risk of recurrence score in patients with early-stage breast cancer with long-term follow-up
Breast Cancer Res, 19 (1), 120
DOI 10.1186/s13058-017-0911-9, PubMed 29137653
Immune Escape in Breast Cancer During In Situ to Invasive Carcinoma Transition
Cancer Discov, 7 (10), 1098-1115
DOI 10.1158/2159-8290.CD-17-0222, PubMed 28652380
Molecular Features of Subtype-Specific Progression from Ductal Carcinoma In Situ to Invasive Breast Cancer
Cell Rep, 16 (4), 1166-1179
DOI 10.1016/j.celrep.2016.06.051, PubMed 27396337
The prognostic role of HER2 expression in ductal breast carcinoma in situ (DCIS); a population-based cohort study
BMC Cancer, 15, 468
DOI 10.1186/s12885-015-1479-3, PubMed 26062614
A conditional transgenic mouse line for targeted expression of the stem cell marker LGR5
Dev Biol, 404 (2), 35-48
DOI 10.1016/j.ydbio.2015.05.002, PubMed 26003047
Glycan-related gene expression signatures in breast cancer subtypes; relation to survival
Mol Oncol, 9 (4), 861-76
DOI 10.1016/j.molonc.2014.12.013, PubMed 25655580
Differential in vivo tumorigenicity of distinct subpopulations from a luminal-like breast cancer xenograft
PLoS One, 9 (11), e113278
DOI 10.1371/journal.pone.0113278, PubMed 25419568
Development and validation of a gene profile predicting benefit of postmastectomy radiotherapy in patients with high-risk breast cancer: a study of gene expression in the DBCG82bc cohort
Clin Cancer Res, 20 (20), 5272-80
DOI 10.1158/1078-0432.CCR-14-0458, PubMed 25149560
Relationship between the prognostic and predictive value of the intrinsic subtypes and a validated gene profile predictive of loco-regional control and benefit from post-mastectomy radiotherapy in patients with high-risk breast cancer
Acta Oncol, 53 (10), 1337-46
DOI 10.3109/0284186X.2014.925580, PubMed 24957550
Systematic assessment of prognostic gene signatures for breast cancer shows distinct influence of time and ER status
BMC Cancer, 14, 211
DOI 10.1186/1471-2407-14-211, PubMed 24645668
Interplay of choline metabolites and genes in patient-derived breast cancer xenografts
Breast Cancer Res, 16 (1), R5
DOI 10.1186/bcr3597, PubMed 24447408
Mutation screening of the TP53 gene by temporal temperature gel electrophoresis (TTGE)
Methods Mol Biol, 1105, 315-24
DOI 10.1007/978-1-62703-739-6_25, PubMed 24623239
Molecular subtypes in ductal carcinoma in situ of the breast and their relation to prognosis: a population-based cohort study
BMC Cancer, 13, 512
DOI 10.1186/1471-2407-13-512, PubMed 24171825
Reliable PCR quantitation of estrogen, progesterone and ERBB2 receptor mRNA from formalin-fixed, paraffin-embedded tissue is independent of prior macro-dissection
Virchows Arch, 463 (6), 775-86
DOI 10.1007/s00428-013-1486-1, PubMed 24100522
Influence of DNA copy number and mRNA levels on the expression of breast cancer related proteins
Mol Oncol, 7 (3), 704-18
DOI 10.1016/j.molonc.2013.02.018, PubMed 23562353
Different labour outcomes in primiparous women that have been subjected to childhood sexual abuse or rape in adulthood: a case-control study in a clinical cohort
BJOG, 120 (4), 487-95
DOI 10.1111/1471-0528.12053, PubMed 23157417
Subtype-specific response to bevacizumab is reflected in the metabolome and transcriptome of breast cancer xenografts
Mol Oncol, 7 (1), 130-42
DOI 10.1016/j.molonc.2012.10.005, PubMed 23142657
Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity
Proc Natl Acad Sci U S A, 109 (16), 6124-9
DOI 10.1073/pnas.1203203109, PubMed 22454501
Integrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signaling
Proc Natl Acad Sci U S A, 109 (8), 2802-7
DOI 10.1073/pnas.1108781108, PubMed 21908711
How to personalise treatment in early breast cancer
Eur J Cancer, 47 Suppl 3, S310-1
DOI 10.1016/S0959-8049(11)70182-4, PubMed 21943994
Ischemia caused by time to freezing induces systematic microRNA and mRNA responses in cancer tissue
Mol Oncol, 5 (6), 564-76
DOI 10.1016/j.molonc.2011.08.004, PubMed 21917534
Glomeruloid microvascular proliferation is associated with lack of response to chemotherapy in breast cancer
Br J Cancer, 105 (1), 9-12
DOI 10.1038/bjc.2011.203, PubMed 21673677
Combining gene signatures improves prediction of breast cancer survival
PLoS One, 6 (3), e17845
DOI 10.1371/journal.pone.0017845, PubMed 21423775
In silico ascription of gene expression differences to tumor and stromal cells in a model to study impact on breast cancer outcome
PLoS One, 5 (11), e14002
DOI 10.1371/journal.pone.0014002, PubMed 21124964
Merging transcriptomics and metabolomics--advances in breast cancer profiling
BMC Cancer, 10, 628
DOI 10.1186/1471-2407-10-628, PubMed 21080935
Genomic architecture characterizes tumor progression paths and fate in breast cancer patients
Sci Transl Med, 2 (38), 38ra47
DOI 10.1126/scitranslmed.3000611, PubMed 20592421
Molecular diversity in ductal carcinoma in situ (DCIS) and early invasive breast cancer
Mol Oncol, 4 (4), 357-68
DOI 10.1016/j.molonc.2010.06.007, PubMed 20663721
Frequent aberrant DNA methylation of ABCB1, FOXC1, PPP2R2B and PTEN in ductal carcinoma in situ and early invasive breast cancer
Breast Cancer Res, 12 (1), R3
DOI 10.1186/bcr2466, PubMed 20056007
Molecular profiling and characterization of luminal-like and basal-like in vivo breast cancer xenograft models
Mol Oncol, 3 (5-6), 469-82
DOI 10.1016/j.molonc.2009.07.003, PubMed 19713161
Integrative analysis of cyclin protein levels identifies cyclin b1 as a classifier and predictor of outcomes in breast cancer
Clin Cancer Res, 15 (11), 3654-62
DOI 10.1158/1078-0432.CCR-08-3293, PubMed 19470724
Data integration from two microarray platforms identifies bi-allelic genetic inactivation of RIC8A in a breast cancer cell line
BMC Med Genomics, 2, 26
DOI 10.1186/1755-8794-2-26, PubMed 19432969
Full sequencing of TP53 identifies identical mutations within in situ and invasive components in breast cancer suggesting clonal evolution
Mol Oncol, 3 (3), 214-9
DOI 10.1016/j.molonc.2009.03.001, PubMed 19403344
Pathway based analysis of SNPs with relevance to 5-FU therapy: relation to intratumoral mRNA expression and survival
Int J Cancer, 123 (3), 577-85
DOI 10.1002/ijc.23541, PubMed 18498133
Extracellular matrix signature identifies breast cancer subgroups with different clinical outcome
J Pathol, 214 (3), 357-67
DOI 10.1002/path.2278, PubMed 18044827
Presence of bone marrow micrometastasis is associated with different recurrence risk within molecular subtypes of breast cancer
Mol Oncol, 1 (2), 160-71
DOI 10.1016/j.molonc.2007.03.004, PubMed 19383292
Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene-expression subtypes of breast cancer
Genes Chromosomes Cancer, 45 (11), 1033-40
DOI 10.1002/gcc.20366, PubMed 16897746
Gene expression profiles do not consistently predict the clinical treatment response in locally advanced breast cancer
Mol Cancer Ther, 5 (11), 2914-8
DOI 10.1158/1535-7163.MCT-06-0126, PubMed 17121939
Distinct molecular mechanisms underlying clinically relevant subtypes of breast cancer: gene expression analyses across three different platforms
BMC Genomics, 7, 127
DOI 10.1186/1471-2164-7-127, PubMed 16729877
Genetic variation in putative regulatory loci controlling gene expression in breast cancer
Proc Natl Acad Sci U S A, 103 (20), 7735-40
DOI 10.1073/pnas.0601893103, PubMed 16684880
Evaluation of MetriGenix custom 4D arrays applied for detection of breast cancer subtypes
BMC Cancer, 6, 59
DOI 10.1186/1471-2407-6-59, PubMed 16536878
Effects of anastrozole on the intratumoral gene expression in locally advanced breast cancer
J Steroid Biochem Mol Biol, 95 (1-5), 105-11
DOI 10.1016/j.jsbmb.2005.04.028, PubMed 16023338
Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival
Proc Natl Acad Sci U S A, 102 (10), 3738-43
DOI 10.1073/pnas.0409462102, PubMed 15701700
Gene expression profiling of breast cancer in relation to estrogen receptor status and estrogen-metabolizing enzymes: clinical implications
Clin Cancer Res, 11 (2 Pt 2), 878s-83s
PubMed 15701881
Mutation screening of the TP53 gene by temporal temperature gradient gel electrophoresis
Methods Mol Biol, 291, 207-16
DOI 10.1385/1-59259-840-4:207, PubMed 15502225
Cell-type-specific responses to chemotherapeutics in breast cancer
Cancer Res, 64 (12), 4218-26
DOI 10.1158/0008-5472.CAN-04-0107, PubMed 15205334
Gene expression patterns in ovarian carcinomas
Mol Biol Cell, 14 (11), 4376-86
DOI 10.1091/mbc.e03-05-0279, PubMed 12960427
Repeated observation of breast tumor subtypes in independent gene expression data sets
Proc Natl Acad Sci U S A, 100 (14), 8418-23
DOI 10.1073/pnas.0932692100, PubMed 12829800
Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors
Proc Natl Acad Sci U S A, 99 (20), 12963-8
DOI 10.1073/pnas.162471999, PubMed 12297621
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
Proc Natl Acad Sci U S A, 98 (19), 10869-74
DOI 10.1073/pnas.191367098, PubMed 11553815
Microarrays in primary breast cancer--lessons from chemotherapy studies
Endocr Relat Cancer, 8 (3), 259-63
DOI 10.1677/erc.0.0080259, PubMed 11566617
Molecular portraits of human breast tumours
Nature, 406 (6797), 747-52
DOI 10.1038/35021093, PubMed 10963602
Chromosome band 9p21 is frequently altered in malignant peripheral nerve sheath tumors: studies of CDKN2A and other genes of the pRB pathway
Genes Chromosomes Cancer, 26 (2), 151-60
DOI 10.1002/(SICI)1098-2264(199910)26:2<151::AID-GCC7>3.0.CO;2-A, PubMed 10469453
Analysis of p53, p16MTS, p21WAF1 and H-ras in archived bladder tumours from workers exposed to aromatic amines
Br J Cancer, 77 (10), 1573-9
DOI 10.1038/bjc.1998.259, PubMed 9635831
Mutation screening of BRCA1 using PTT and LOH analysis at 17q21 in breast carcinomas from familial and non-familial cases
Breast Cancer Res Treat, 48 (3), 259-64
DOI 10.1023/a:1005953519972, PubMed 9598872
Truncating somatic mutation in exon 15 of the APC gene is a rare event in human breast carcinomas. Mutations in brief no. 179. Online
Hum Mutat, 12 (3), 215
PubMed 10660330
Database of p53 gene somatic mutations in human tumors and cell lines
Nucleic Acids Res, 22 (17), 3551-5
PubMed 7937055
Review articles
Imagine beyond: recent breakthroughs and next challenges in mammary gland biology and breast cancer research
J Mammary Gland Biol Neoplasia, 28 (1), 17
DOI 10.1007/s10911-023-09544-y, PubMed 37450065
From autonomy to community; new perspectives on tumorigenicity and therapy resistance
Cancer Treat Rev, 41 (10), 809-13
DOI 10.1016/j.ctrv.2015.10.004, PubMed 26519005
Lessons learned from the intrinsic subtypes of breast cancer in the quest for precision therapy
Br J Surg, 101 (8), 925-38
DOI 10.1002/bjs.9562, PubMed 24849143
Molecular subclasses of breast cancer: how do we define them? The IMPAKT 2012 Working Group Statement
Ann Oncol, 23 (12), 2997-3006
DOI 10.1093/annonc/mds586, PubMed 23166150
Triple-negative breast cancer: present challenges and new perspectives
Mol Oncol, 4 (3), 209-29
DOI 10.1016/j.molonc.2010.04.006, PubMed 20537966
Glycan gene expression signatures in normal and malignant breast tissue; possible role in diagnosis and progression
Mol Oncol, 4 (2), 98-118
DOI 10.1016/j.molonc.2009.12.001, PubMed 20060370
Molecular classification of breast tumors: toward improved diagnostics and treatments
Methods Mol Biol, 360, 91-114
DOI 10.1385/1-59745-165-7:91, PubMed 17172726
NMD microarray analysis for rapid genome-wide screen of mutated genes in cancer
Cell Oncol, 27 (3), 169-73
DOI 10.1155/2005/478316, PubMed 16037637
NMD microarray analysis for rapid genome-wide screen of mutated genes in cancer
Cell. Oncol., 27 (3), 169-173
Genomics in breast cancer-therapeutic implications
Nat Clin Pract Oncol, 2 (1), 26-33
DOI 10.1038/ncponc0072, PubMed 16264853
Molecular portraits of breast cancer: tumour subtypes as distinct disease entities
Eur J Cancer, 40 (18), 2667-75
DOI 10.1016/j.ejca.2004.08.021, PubMed 15571950
[Microarray technology--potential in cancer research]
Tidsskr Nor Laegeforen, 121 (21), 2498-503
PubMed 11875927
Screening for p53 gene mutations in archived tumors of workers occupationally exposed to carcinogens: examples from analysis of bladder tumors
J Occup Environ Med, 37 (1), 59-68
DOI 10.1097/00043764-199501000-00009, PubMed 7620944
Other articles
The Impact of Gene Expression Patterns in Breast Cancer
Clin Chem, 62 (8), 1150-1
DOI 10.1373/clinchem.2015.253229, PubMed 27022070
The importance of gene-centring microarray data
Lancet Oncol, 11 (8), 719-20; author reply 720-1
DOI 10.1016/S1470-2045(10)70174-1, PubMed 20688275
On the molecular biology of breast cancer
Mol Oncol, 4 (3), 171-3
DOI 10.1016/j.molonc.2010.04.007, PubMed 20483673
Presence of bone marrow micrometastasis is associated with different recurrence risk within molecular subtypes of breast cancer (vol 1, pg 160, 2007)
Mol. Oncol., 4 (2), 169
DOI 10.1016/j.molonc.2010.01.003
Introducing molecular subtyping of breast cancer into the clinic?
J Clin Oncol, 27 (8), 1153-4
DOI 10.1200/JCO.2008.20.6276, PubMed 19204193
Book chapters
Expression profiling of breast cancer: From molecular portraits to clinical utility.
In Oncogenomics: Molecular approaches to cancer (Brenner C, Duggan DJ, eds.), John Wiley & Sons, Inc., New York
PublikaID 67, ISBN 0-471-22592-4
Theses
Tumor genotypes and phenotypes associated with exposure, aggressiveness and clinical outcome: methodological approoaches [sic]
Department of Genetics, The Norwegian Radium Hospital, Department Group of Laboratory Medicine, Oslo, 1 b. (flere pag.)
BIBSYS 001846469, ISBN 82-7633-157-2