Publication list - Publika - Scientific publications from Oslo University Hospital

Publications by Frode Willoch

54 publications found

Original articles

Becker-Bense S, Willoch F, Stephan T, Brendel M, Yakushev I, Habs M, Ziegler S, Herz M, Schwaiger M, Dieterich M, Bartenstein P (2020)
Direct comparison of activation maps during galvanic vestibular stimulation: A hybrid H2[15 O] PET-BOLD MRI activation study
PLoS One, 15 (5), e0233262
DOI 10.1371/journal.pone.0233262, PubMed 32413079

Nanni C, Zanoni L, Bach-Gansmo T, Minn H, Willoch F, Bogsrud TV, Edward EP, Savir-Baruch B, Teoh E, Ingram F, Fanti S, Schuster DM (2019)
[¹⁸F]Fluciclovine PET/CT: joint EANM and SNMMI procedure guideline for prostate cancer imaging-version 1.0
Eur J Nucl Med Mol Imaging, 47 (3), 579-591
DOI 10.1007/s00259-019-04614-y, PubMed 31822959

Tulipan AJ, Hole KH, Vlatkovic L, Revheim ME, Reijnen JS, Willoch F, Seierstad T, Lilleby W (2018)
Localization of radio-recurrence within the prostate: anti-3-18F-FACBC PET/CT compared with multiparametric MRI using histopathology as reference standard
Acta Radiol, 60 (8), 1028-1038
DOI 10.1177/0284185118810977, PubMed 30379559

Tungen JE, Aursnes M, Ramon S, Colas RA, Serhan CN, Olberg DE, Nuruddin S, Willoch F, Hansen TV (2018)
Synthesis of protectin D1 analogs: novel pro-resolution and radiotracer agents
Org Biomol Chem, 16 (36), 6818-6823
DOI 10.1039/c8ob01232f, PubMed 30204204

Selnæs KM, Krüger-Stokke B, Elschot M, Willoch F, Størkersen Ø, Sandsmark E, Moestue SA, Tessem MB, Halvorsen D, Kjøbli E, Angelsen A, Langørgen S, Bertilsson H, Bathen TF (2018)
¹⁸F-Fluciclovine PET/MRI for preoperative lymph node staging in high-risk prostate cancer patients
Eur Radiol, 28 (8), 3151-3159
DOI 10.1007/s00330-017-5213-1, PubMed 29294158

Eikemo M, Biele G, Willoch F, Thomsen L, Leknes S (2017)
Opioid Modulation of Value-Based Decision-Making in Healthy Humans
Neuropsychopharmacology, 42 (9), 1833-1840
DOI 10.1038/npp.2017.58, PubMed 28294136

Bach-Gansmo T, Nanni C, Nieh PT, Zanoni L, Bogsrud TV, Sletten H, Korsan KA, Kieboom J, Tade FI, Odewole O, Chau A, Ward P, Goodman MM, Fanti S, Schuster DM, Willoch F (2016)
Multisite Experience of the Safety, Detection Rate and Diagnostic Performance of Fluciclovine (¹⁸F) Positron Emission Tomography/Computerized Tomography Imaging in the Staging of Biochemically Recurrent Prostate Cancer
J Urol, 197 (3 Pt 1), 676-683
DOI 10.1016/j.juro.2016.09.117, PubMed 27746282

Eikemo M, Løseth GE, Johnstone T, Gjerstad J, Willoch F, Leknes S (2016)
Sweet taste pleasantness is modulated by morphine and naltrexone
Psychopharmacology (Berl), 233 (21-22), 3711-3723
DOI 10.1007/s00213-016-4403-x, PubMed 27538675

Chelnokova O, Laeng B, Løseth G, Eikemo M, Willoch F, Leknes S (2016)
The µ-opioid system promotes visual attention to faces and eyes
Soc Cogn Affect Neurosci, 11 (12), 1902-1909
DOI 10.1093/scan/nsw116, PubMed 27531386

Schoultz BW, Hjørnevik T, Reed BJ, Marton J, Coello CS, Willoch F, Henriksen G (2014)
Synthesis and evaluation of three structurally related ¹⁸F-labeled orvinols of different intrinsic activities: 6-O-[¹⁸F]fluoroethyl-diprenorphine ([¹⁸F]FDPN), 6-O-[¹⁸F]fluoroethyl-buprenorphine ([¹⁸F]FBPN), and 6-O-[¹⁸F]fluoroethyl-phenethyl-orvinol ([¹⁸F]FPEO)
J Med Chem, 57 (12), 5464-9
DOI 10.1021/jm500503k, PubMed 24933507

Boardman NT, Aronsen JM, Louch WE, Sjaastad I, Willoch F, Christensen G, Sejersted O, Aasum E (2014)
Impaired left ventricular mechanical and energetic function in mice after cardiomyocyte-specific excision of Serca2
Am J Physiol Heart Circ Physiol, 306 (7), H1018-24
DOI 10.1152/ajpheart.00741.2013, PubMed 24486508

Schoultz BW, Reed BJ, Marton J, Willoch F, Henriksen G (2013)
A fully automated radiosynthesis of [18F]fluoroethyl-diprenorphine on a single module by use of SPE cartridges for preparation of high quality 2-[18F]fluoroethyl tosylate
Molecules, 18 (6), 7271-8
DOI 10.3390/molecules18067271, PubMed 23787515

Coello C, Willoch F, Selnes P, Gjerstad L, Fladby T, Skretting A (2013)
Correction of partial volume effect in (18)F-FDG PET brain studies using coregistered MR volumes: voxel based analysis of tracer uptake in the white matter
Neuroimage, 72, 183-92
DOI 10.1016/j.neuroimage.2013.01.043, PubMed 23370062

Coello C, Hjornevik T, Courivaud F, Willoch F (2011)
Anatomical standardization of small animal brain FDG-PET images using synthetic functional template: experimental comparison with anatomical template
J Neurosci Methods, 199 (1), 166-72
DOI 10.1016/j.jneumeth.2011.04.026, PubMed 21550366

Hjornevik T, Schoultz BW, Marton J, Gjerstad J, Drzezga A, Henriksen G, Willoch F (2010)
Spinal long-term potentiation is associated with reduced opioid neurotransmission in the rat brain
Clin Physiol Funct Imaging, 30 (4), 285-93
DOI 10.1111/j.1475-097X.2010.00939.x, PubMed 20662879

Schoultz BW, Hjornevik T, Willoch F, Marton J, Noda A, Murakami Y, Miyoshi S, Nishimura S, Arstad E, Drzezga A, Matsunari I, Henriksen G (2010)
Evaluation of the kappa-opioid receptor-selective tracer [(11)C]GR103545 in awake rhesus macaques
Eur J Nucl Med Mol Imaging, 37 (6), 1174-80
DOI 10.1007/s00259-010-1384-6, PubMed 20157708

Marton J, Schoultz BW, Hjørnevik T, Drzezga A, Yousefi BH, Wester HJ, Willoch F, Henriksen G (2009)
Synthesis and evaluation of a full-agonist orvinol for PET-imaging of opioid receptors: [11C]PEO
J Med Chem, 52 (18), 5586-9
DOI 10.1021/jm900892x, PubMed 19694469

Hjornevik T, Jacobsen LM, Qu H, Bjaalie JG, Gjerstad J, Willoch F (2008)
Metabolic plasticity in the supraspinal pain modulating circuitry after noxious stimulus-induced spinal cord LTP
Pain, 140 (3), 456-464
DOI 10.1016/j.pain.2008.09.029, PubMed 19004552

Schoultz BW, Arstad E, Marton J, Willoch F, Drzezga A, Wester HJ, Henriksen G (2008)
A New Method for Radiosynthesis of C-Labeled Carbamate Groups and its Application for a Highly Efficient Synthesis of the Kappa-Opioid Receptor Tracer [C]GR103545
Open Med Chem J, 2, 72-4
DOI 10.2174/1874104500802010072, PubMed 19662146

Fjell AM, Walhovd KB, Amlien I, Bjørnerud A, Reinvang I, Gjerstad L, Cappelen T, Willoch F, Due-Tønnessen P, Grambaite R, Skinningsrud A, Stenset V, Fladby T (2008)
Morphometric changes in the episodic memory network and tau pathologic features correlate with memory performance in patients with mild cognitive impairment
AJNR Am J Neuroradiol, 29 (6), 1183-9
DOI 10.3174/ajnr.A1059, PubMed 18544670

Hjornevik T, Leergaard TB, Darine D, Moldestad O, Dale AM, Willoch F, Bjaalie JG (2007)
Three-dimensional atlas system for mouse and rat brain imaging data
Front Neuroinform, 1, 4
DOI 10.3389/neuro.11.004.2007, PubMed 18974799

Wagner KJ, Sprenger T, Kochs EF, Tölle TR, Valet M, Willoch F (2007)
Imaging human cerebral pain modulation by dose-dependent opioid analgesia: a positron emission tomography activation study using remifentanil
Anesthesiology, 106 (3), 548-56
DOI 10.1097/00000542-200703000-00020, PubMed 17325514

Teipel SJ, Willoch F, Ishii K, Bürger K, Drzezga A, Engel R, Bartenstein P, Möller HJ, Schwaiger M, Hampel H (2006)
Resting state glucose utilization and the CERAD cognitive battery in patients with Alzheimer's disease
Neurobiol Aging, 27 (5), 681-90
DOI 10.1016/j.neurobiolaging.2005.03.015, PubMed 15908048

Sprenger T, Willoch F, Miederer M, Schindler F, Valet M, Berthele A, Spilker ME, Förderreuther S, Straube A, Stangier I, Wester HJ, Tölle TR (2006)
Opioidergic changes in the pineal gland and hypothalamus in cluster headache: a ligand PET study
Neurology, 66 (7), 1108-10
DOI 10.1212/01.wnl.0000204225.15947.f8, PubMed 16606930

Sprenger T, Valet M, Boecker H, Henriksen G, Spilker ME, Willoch F, Wagner KJ, Wester HJ, Tölle TR (2006)
Opioidergic activation in the medial pain system after heat pain
Pain, 122 (1-2), 63-7
DOI 10.1016/j.pain.2006.01.003, PubMed 16527398

Henriksen G, Platzer S, Hauser A, Willoch F, Berthele A, Schwaiger M, Wester HJ (2005)
18F-labeled sufentanil for PET-imaging of mu-opioid receptors
Bioorg Med Chem Lett, 15 (7), 1773-7
DOI 10.1016/j.bmcl.2005.02.049, PubMed 15780604

Valet M, Sprenger T, Boecker H, Willoch F, Rummeny E, Conrad B, Erhard P, Tolle TR (2004)
Distraction modulates connectivity of the cingulo-frontal cortex and the midbrain during pain--an fMRI analysis
Pain, 109 (3), 399-408
DOI 10.1016/j.pain.2004.02.033, PubMed 15157701

Willoch F, Schindler F, Wester HJ, Empl M, Straube A, Schwaiger M, Conrad B, Tölle TR (2004)
Central poststroke pain and reduced opioid receptor binding within pain processing circuitries: a [11C]diprenorphine PET study
Pain, 108 (3), 213-220
DOI 10.1016/j.pain.2003.08.014, PubMed 15030940

Drzezga A, Lautenschlager N, Siebner H, Riemenschneider M, Willoch F, Minoshima S, Schwaiger M, Kurz A (2003)
Cerebral metabolic changes accompanying conversion of mild cognitive impairment into Alzheimer's disease: a PET follow-up study
Eur J Nucl Med Mol Imaging, 30 (8), 1104-13
DOI 10.1007/s00259-003-1194-1, PubMed 12764551

Willoch F, Gamringer U, Medele R, Steude U, Tölle TR, PET activation study (2003)
Analgesia by electrostimulation of the trigeminal ganglion in patients with trigeminopathic pain: a PET activation study
Pain, 103 (1-2), 119-30
DOI 10.1016/s0304-3959(02)00423-2, PubMed 12749966

Wagner KJ, Willoch F, Kochs EF, Siessmeier T, Tölle TR, Schwaiger M, Bartenstein P (2001)
Dose-dependent regional cerebral blood flow changes during remifentanil infusion in humans: a positron emission tomography study
Anesthesiology, 94 (5), 732-9
DOI 10.1097/00000542-200105000-00008, PubMed 11388521

Ishii K, Willoch F, Minoshima S, Drzezga A, Ficaro EP, Cross DJ, Kuhl DE, Schwaiger M (2001)
Statistical brain mapping of 18F-FDG PET in Alzheimer's disease: validation of anatomic standardization for atrophied brains
J Nucl Med, 42 (4), 548-57
PubMed 11337540

Siebner H, Peller M, Bartenstein P, Willoch F, Rossmeier C, Schwaiger M, Conrad B (2001)
Activation of frontal premotor areas during suprathreshold transcranial magnetic stimulation of the left primary sensorimotor cortex: a glucose metabolic PET study
Hum Brain Mapp, 12 (3), 157-67
DOI 10.1002/1097-0193(200103)12:3<157::aid-hbm1012>3.0.co;2-v, PubMed 11170307

Rosén G, Willoch F, Bartenstein P, Berner N, Røsjø S (2001)
Neurophysiological processes underlying the phantom limb pain experience and the use of hypnosis in its clinical management: an intensive examination of two patients
Int J Clin Exp Hypn, 49 (1), 38-55
DOI 10.1080/00207140108410378, PubMed 11190791

Willoch F, Rosen G, Tölle TR, Oye I, Wester HJ, Berner N, Schwaiger M, Bartenstein P (2000)
Phantom limb pain in the human brain: unraveling neural circuitries of phantom limb sensations using positron emission tomography
Ann Neurol, 48 (6), 842-9
PubMed 11117540

Wester HJ, Willoch F, Tölle TR, Munz F, Herz M, Oye I, Schadrack J, Schwaiger M, Bartenstein P (2000)
6-O-(2-[18F]fluoroethyl)-6-O-desmethyldiprenorphine ([18F]DPN): synthesis, biologic evaluation, and comparison with [11C]DPN in humans
J Nucl Med, 41 (7), 1279-86
PubMed 10914922

Wester HJ, Willoch F, Tolle TR, Munz F, Herz M, Oye I, Schadrack J, Schwaiger M, Bartenstein P (2000)
6-O-(2-[F-18]Fluoroethyl)-6-O-desmethyldiprenorphine ([F-18]DPN): Synthesis, biologic evaluation, and comparison with [C-11]DPN in humans
J. Nucl. Med., 41 (7), 1279-1286

Siebner HR, Peller M, Willoch F, Minoshima S, Boecker H, Auer C, Drzezga A, Conrad B, Bartenstein P (2000)
Lasting cortical activation after repetitive TMS of the motor cortex: a glucose metabolic study
Neurology, 54 (4), 956-63
DOI 10.1212/wnl.54.4.956, PubMed 10690992

Siebner HR, Peller M, Willoch F, Auer C, Bartenstein P, Drzezga A, Schwaiger M, Conrad B (1999)
Imaging functional activation of the auditory cortex during focal repetitive transcranial magnetic stimulation of the primary motor cortex in normal subjects
Neurosci Lett, 270 (1), 37-40
DOI 10.1016/s0304-3940(99)00454-1, PubMed 10454140

Willoch F, Tölle TR, Wester HJ, Munz F, Petzold A, Schwaiger M, Conrad B, Bartenstein P (1999)
Central pain after pontine infarction is associated with changes in opioid receptor binding: a PET study with 11C-diprenorphine
AJNR Am J Neuroradiol, 20 (4), 686-90
PubMed 10319982

Schadrack J, Willoch F, Platzer S, Bartenstein P, Mahal B, Dworzak D, Wester HJ, Zieglgänsberger W, Tölle TR (1999)
Opioid receptors in the human cerebellum: evidence from [11C]diprenorphine PET, mRNA expression and autoradiography
Neuroreport, 10 (3), 619-24
DOI 10.1097/00001756-199902250-00032, PubMed 10208600

Tölle TR, Kaufmann T, Siessmeier T, Lautenbacher S, Berthele A, Munz F, Zieglgänsberger W, Willoch F, Schwaiger M, Conrad B, Bartenstein P (1999)
Region-specific encoding of sensory and affective components of pain in the human brain: a positron emission tomography correlation analysis
Ann Neurol, 45 (1), 40-7
DOI 10.1002/1531-8249(199901)45:1<40::aid-art8>3.0.co;2-l, PubMed 9894875

Schadrack J, Neto FL, Ableitner A, Castro-Lopes JM, Willoch F, Bartenstein P, Zieglgänsberger W, Tölle TR (1999)
Metabolic activity changes in the rat spinal cord during adjuvant monoarthritis
Neuroscience, 94 (2), 595-605
DOI 10.1016/s0306-4522(99)00186-4, PubMed 10579220

Kurz A, Riemenschneider M, Buch K, Willoch F, Bartenstein P, Müller U, Guder W (1998)
Tau protein in cerebrospinal fluid is significantly increased at the earliest clinical stage of Alzheimer disease
Alzheimer Dis Assoc Disord, 12 (4), 372-7
DOI 10.1097/00002093-199812000-00020, PubMed 9876968

Buch K, Riemenschneider M, Bartenstein P, Willoch F, Müller U, Schmolke M, Nolde T, Steinmann C, Guder WG, Kurz A (1998)
[Tau protein. A potential biological indicator for early detection of Alzheimer disease]
Nervenarzt, 69 (5), 379-85
DOI 10.1007/s001150050286, PubMed 9629553

Siebner HR, Willoch F, Peller M, Auer C, Boecker H, Conrad B, Bartenstein P (1998)
Imaging brain activation induced by long trains of repetitive transcranial magnetic stimulation
Neuroreport, 9 (5), 943-8
DOI 10.1097/00001756-199803300-00033, PubMed 9579695

Bartenstein P, Minoshima S, Hirsch C, Buch K, Willoch F, Mösch D, Schad D, Schwaiger M, Kurz A (1997)
Quantitative assessment of cerebral blood flow in patients with Alzheimer's disease by SPECT
J Nucl Med, 38 (7), 1095-101
PubMed 9225797

Hirsch C, Bartenstein P, Minoshima S, Mösch D, Willoch F, Buch K, Schad D, Schwaiger M, Kurz A (1997)
Reduction of regional cerebral blood flow and cognitive impairment in patients with Alzheimer's disease: evaluation of an observer-independent analytic approach
Dement Geriatr Cogn Disord, 8 (2), 98-104
DOI 10.1159/000106613, PubMed 9065322

Review articles

Boecker H, Henriksen G, Sprenger T, Miederer I, Willoch F, Valet M, Berthele A, Tölle TR (2008)
Positron emission tomography ligand activation studies in the sports sciences: measuring neurochemistry in vivo
Methods, 45 (4), 307-18
DOI 10.1016/j.ymeth.2008.07.003, PubMed 18674621

Henriksen G, Willoch F (2007)
Imaging of opioid receptors in the central nervous system
Brain, 131 (Pt 5), 1171-96
DOI 10.1093/brain/awm255, PubMed 18048446

Henriksen G, Willoch F, Talbot PS, Wester HJ (2006)
Recent development and potential use of mu- and kappa-opioid receptor ligands in positron emission tomography studies
Drug Dev. Res., 67 (12), 890-904
DOI 10.1002/ddr.20161