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Publications by Vanessa Dumeaux

60 publications found

Original articles

Lismer A, Shao X, Dumargne MC, Lafleur C, Lambrot R, Chan D, Toft G, Bonde JP, MacFarlane AJ, Bornman R, Aneck-Hahn N, Patrick S, Bailey JM, de Jager C, Dumeaux V, Trasler JM, Kimmins S (2024)
The Association between Long-Term DDT or DDE Exposures and an Altered Sperm Epigenome-a Cross-Sectional Study of Greenlandic Inuit and South African VhaVenda Men
Environ Health Perspect, 132 (1), 17008
DOI 10.1289/EHP12013, PubMed 38294233

Rowland ME, Jiang Y, Shafiq S, Ghahramani A, Pena-Ortiz MA, Dumeaux V, Bérubé NG (2023)
Systemic and intrinsic functions of ATRX in glial cell fate and CNS myelination in male mice
Nat Commun, 14 (1), 7090
DOI 10.1038/s41467-023-42752-y, PubMed 37925436

Dumeaux V, Massahi S, Bettauer V, Mottola A, Dukovny A, Khurdia SS, Costa ACBP, Omran RP, Simpson S, Xie JL, Whiteway M, Berman J, Hallett MT (2023)
Candida albicans exhibits heterogeneous and adaptive cytoprotective responses to antifungal compounds
Elife, 12
DOI 10.7554/eLife.81406, PubMed 37888959

Simpson S, Bettauer V, Ramachandran A, Kraemer S, Mahon S, Medina M, Vallès Y, Dumeaux V, Vallès H, Walsh D, Hallett MT (2023)
A metagenomic-based study of two sites from the Barbadian reef system
Coral Reefs, 42 (2), 359-366
DOI 10.1007/s00338-022-02330-y, PubMed 37009568

Jeyarajah MJ, Jaju Bhattad G, Kelly RD, Baines KJ, Jaremek A, Yang FP, Okae H, Arima T, Dumeaux V, Renaud SJ (2022)
The multifaceted role of GCM1 during trophoblast differentiation in the human placenta
Proc Natl Acad Sci U S A, 119 (49), e2203071119
DOI 10.1073/pnas.2203071119, PubMed 36442132

Bettauer V, Costa ACBP, Omran RP, Massahi S, Kirbizakis E, Simpson S, Dumeaux V, Law C, Whiteway M, Hallett MT (2022)
A Deep Learning Approach to Capture the Essence of Candida albicans Morphologies
Microbiol Spectr, 10 (5), e0147222
DOI 10.1128/spectrum.01472-22, PubMed 35972285

Pepin AS, Lafleur C, Lambrot R, Dumeaux V, Kimmins S (2022)
Sperm histone H3 lysine 4 tri-methylation serves as a metabolic sensor of paternal obesity and is associated with the inheritance of metabolic dysfunction
Mol Metab, 59, 101463
DOI 10.1016/j.molmet.2022.101463, PubMed 35183795

Parvizi Omran R, Ramírez-Zavala B, Aji Tebung W, Yao S, Feng J, Law C, Dumeaux V, Morschhäuser J, Whiteway M (2022)
The zinc cluster transcription factor Rha1 is a positive filamentation regulator in Candida albicans
Genetics, 220 (1)
DOI 10.1093/genetics/iyab155, PubMed 34849863

Lambrot R, Chan D, Shao X, Aarabi M, Kwan T, Bourque G, Moskovtsev S, Librach C, Trasler J, Dumeaux V, Kimmins S (2021)
Whole-genome sequencing of H3K4me3 and DNA methylation in human sperm reveals regions of overlap linked to fertility and development
Cell Rep, 36 (3), 109418
DOI 10.1016/j.celrep.2021.109418, PubMed 34289352

Lismer A, Lambrot R, Lafleur C, Dumeaux V, Kimmins S (2021)
ChIP-seq protocol for sperm cells and embryos to assess environmental impacts and epigenetic inheritance
STAR Protoc, 2 (2), 100602
DOI 10.1016/j.xpro.2021.100602, PubMed 34159325

Costa ACBP, Omran RP, Law C, Dumeaux V, Whiteway M (2021)
Signal-mediated localization of Candida albicans pheromone response pathway components
G3 (Bethesda), 11 (3)
DOI 10.1093/g3journal/jkaa033, PubMed 33793759

Lismer A, Dumeaux V, Lafleur C, Lambrot R, Brind'Amour J, Lorincz MC, Kimmins S (2021)
Histone H3 lysine 4 trimethylation in sperm is transmitted to the embryo and associated with diet-induced phenotypes in the offspring
Dev Cell, 56 (5), 671-686.e6
DOI 10.1016/j.devcel.2021.01.014, PubMed 33596408

Shrivastava M, Feng J, Coles M, Clark B, Islam A, Dumeaux V, Whiteway M (2021)
Modulation of the complex regulatory network for methionine biosynthesis in fungi
Genetics, 217 (2)
DOI 10.1093/genetics/iyaa049, PubMed 33724418

Lismer A, Siklenka K, Lafleur C, Dumeaux V, Kimmins S (2020)
Sperm histone H3 lysine 4 trimethylation is altered in a genetic mouse model of transgenerational epigenetic inheritance
Nucleic Acids Res, 48 (20), 11380-11393
DOI 10.1093/nar/gkaa712, PubMed 33068438

Tamming RJ, Dumeaux V, Jiang Y, Shafiq S, Langlois L, Ellegood J, Qiu LR, Lerch JP, Bérubé NG (2020)
Atrx Deletion in Neurons Leads to Sexually Dimorphic Dysregulation of miR-137 and Spatial Learning and Memory Deficits
Cell Rep, 31 (13), 107838
DOI 10.1016/j.celrep.2020.107838, PubMed 32610139

Jaju Bhattad G, Jeyarajah MJ, McGill MG, Dumeaux V, Okae H, Arima T, Lajoie P, Bérubé NG, Renaud SJ (2020)
Histone deacetylase 1 and 2 drive differentiation and fusion of progenitor cells in human placental trophoblasts
Cell Death Dis, 11 (5), 311
DOI 10.1038/s41419-020-2500-6, PubMed 32366868

Rakovitch E, Sutradhar R, Hallett M, Thompson AM, Gu S, Dumeaux V, Whelan TJ, Paszat L (2019)
The time-varying effect of radiotherapy after breast-conserving surgery for DCIS
Breast Cancer Res Treat, 178 (1), 221-230
DOI 10.1007/s10549-019-05377-8, PubMed 31368035

Costa ACBP, Omran RP, Correia-Mesquita TO, Dumeaux V, Whiteway M (2019)
Screening of Candida albicans GRACE library revealed a unique pattern of biofilm formation under repression of the essential gene ILS1
Sci Rep, 9 (1), 9187
DOI 10.1038/s41598-019-45624-y, PubMed 31235750

Fjukstad B, Dumeaux V, Hallett M, Bongo LA (2019)
Reproducible Data Analysis Pipelines for Precision Medicine
EUROMICRO WORKSHOP P, 299-306
DOI 10.1109/EMPDP.2019.8671623

Islam A, Tebbji F, Mallick J, Regan H, Dumeaux V, Omran RP, Whiteway M (2018)
Mms21: A Putative SUMO E3 Ligase in Candida albicans That Negatively Regulates Invasiveness and Filamentation, and Is Required for the Genotoxic and Cellular Stress Response
Genetics, 211 (2), 579-595
DOI 10.1534/genetics.118.301769, PubMed 30530734

Traboulsi T, El Ezzy M, Dumeaux V, Audemard E, Mader S (2018)
Role of SUMOylation in differential ERα transcriptional repression by tamoxifen and fulvestrant in breast cancer cells
Oncogene, 38 (7), 1019-1037
DOI 10.1038/s41388-018-0468-9, PubMed 30190545

Dumeaux V, Fjukstad B, Fjosne HE, Frantzen JO, Holmen MM, Rodegerdts E, Schlichting E, Børresen-Dale AL, Bongo LA, Lund E, Hallett M (2017)
Interactions between the tumor and the blood systemic response of breast cancer patients
PLoS Comput Biol, 13 (9), e1005680
DOI 10.1371/journal.pcbi.1005680, PubMed 28957325

Paquet ER, Lesurf R, Tofigh A, Dumeaux V, Hallett MT (2017)
Erratum to: Detecting gene signature activation in breast cancer in an absolute, single-patient manner
Breast Cancer Res, 19 (1), 48
DOI 10.1186/s13058-017-0842-5, PubMed 28407814

Paquet ER, Lesurf R, Tofigh A, Dumeaux V, Hallett MT (2017)
Detecting gene signature activation in breast cancer in an absolute, single-patient manner
Breast Cancer Res, 19 (1), 32
DOI 10.1186/s13058-017-0824-7, PubMed 28327201

Fjukstad B, Dumeaux V, Olsen KS, Lund E, Hallett M, Bongo LA (2017)
Building Applications for Interactive Data Exploration in Systems Biology
ACM-BCB' 2017: PROCEEDINGS OF THE 8TH ACM INTERNATIONAL CONFERENCE ON BIOINFORMATICS, COMPUTATIONAL BIOLOGY,AND HEALTH INFORMATICS, 556-561
DOI 10.1145/3107411.3107481

Tofigh A, Suderman M, Paquet ER, Livingstone J, Bertos N, Saleh SM, Zhao H, Souleimanova M, Cory S, Lesurf R, Shahalizadeh S, Garcia Lopez N, Riazalhosseini Y, Omeroglu A, Ursini-Siegel J, Park M, Dumeaux V, Hallett M (2014)
The prognostic ease and difficulty of invasive breast carcinoma
Cell Rep, 9 (1), 129-142
DOI 10.1016/j.celrep.2014.08.073, PubMed 25284793

Dumeaux V, Ursini-Siegel J, Flatberg A, Fjosne HE, Frantzen JO, Holmen MM, Rodegerdts E, Schlichting E, Lund E (2014)
Peripheral blood cells inform on the presence of breast cancer: a population-based case-control study
Int J Cancer, 136 (3), 656-67
DOI 10.1002/ijc.29030, PubMed 24931809

Gavrilyuk O, Braaten T, Skeie G, Weiderpass E, Dumeaux V, Lund E (2014)
High coffee consumption and different brewing methods in relation to postmenopausal endometrial cancer risk in the Norwegian women and cancer study: a population-based prospective study
BMC Womens Health, 14, 48
DOI 10.1186/1472-6874-14-48, PubMed 24666820

Ritte R, Tikk K, Lukanova A, Tjønneland A, Olsen A, Overvad K, Dossus L, Fournier A, Clavel-Chapelon F, Grote V, Boeing H, Aleksandrova K, Trichopoulou A, Lagiou P, Trichopoulos D, Palli D, Berrino F, Mattiello A, Tumino R, Sacerdote C, Quirós JR, Buckland G, Molina-Montes E, Chirlaque MD, Ardanaz E et al. (2013)
Reproductive factors and risk of hormone receptor positive and negative breast cancer: a cohort study
BMC Cancer, 13, 584
DOI 10.1186/1471-2407-13-584, PubMed 24321460

Landmark-Høyvik H, Dumeaux V, Nebdal D, Lund E, Tost J, Kamatani Y, Renault V, Børresen-Dale AL, Kristensen V, Edvardsen H (2013)
Genome-wide association study in breast cancer survivors reveals SNPs associated with gene expression of genes belonging to MHC class I and II
Genomics, 102 (4), 278-87
DOI 10.1016/j.ygeno.2013.07.006, PubMed 23880221

González CA, Megraud F, Buissonniere A, Lujan Barroso L, Agudo A, Duell EJ, Boutron-Ruault MC, Clavel-Chapelon F, Palli D, Krogh V, Mattiello A, Tumino R, Sacerdote C, Quirós JR, Sanchez-Cantalejo E, Navarro C, Barricarte A, Dorronsoro M, Khaw KT, Wareham N, Allen NE, Tsilidis KK, Bas Bueno-de-Mesquita H, Jeurnink SM, Numans ME et al. (2011)
Helicobacter pylori infection assessed by ELISA and by immunoblot and noncardia gastric cancer risk in a prospective study: the Eurgast-EPIC project
Ann Oncol, 23 (5), 1320-1324
DOI 10.1093/annonc/mdr384, PubMed 21917738

Rylander C, Dumeaux V, Olsen KS, Waaseth M, Sandanger TM, Lund E (2011)
Using blood gene signatures for assessing effects of exposure to perfluoroalkyl acids (PFAAs) in humans: the NOWAC postgenome study
Int J Mol Epidemiol Genet, 2 (3), 207-16
PubMed 21915359

Waaseth M, Olsen KS, Rylander C, Lund E, Dumeaux V (2011)
Sex hormones and gene expression signatures in peripheral blood from postmenopausal women - the NOWAC postgenome study
BMC Med Genomics, 4, 29
DOI 10.1186/1755-8794-4-29, PubMed 21453500

Bakken K, Fournier A, Lund E, Waaseth M, Dumeaux V, Clavel-Chapelon F, Fabre A, Hémon B, Rinaldi S, Chajes V, Slimani N, Allen NE, Reeves GK, Bingham S, Khaw KT, Olsen A, Tjønneland A, Rodriguez L, Sánchez MJ, Etxezarreta PA, Ardanaz E, Tormo MJ, Peeters PH, van Gils CH, Steffen A et al. (2011)
Menopausal hormone therapy and breast cancer risk: impact of different treatments. The European Prospective Investigation into Cancer and Nutrition
Int J Cancer, 128 (1), 144-56
DOI 10.1002/ijc.25314, PubMed 20232395

Landmark-Høyvik H, Dumeaux V, Reinertsen KV, Edvardsen H, Fosså SD, Børresen-Dale AL (2010)
Blood gene expression profiling of breast cancer survivors experiencing fibrosis
Int J Radiat Oncol Biol Phys, 79 (3), 875-83
DOI 10.1016/j.ijrobp.2010.09.052, PubMed 21129856

Leufkens AM, Van Duijnhoven FJ, Siersema PD, Boshuizen HC, Vrieling A, Agudo A, Gram IT, Weiderpass E, Dahm C, Overvad K, Tjønneland A, Olsen A, Boutron-Ruault MC, Clavel-Chapelon F, Morois S, Palli D, Grioni S, Tumino R, Sacerdote C, Mattiello A, Herman S, Kaaks R, Steffen A, Boeing H, Trichopoulou A et al. (2010)
Cigarette smoking and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition study
Clin Gastroenterol Hepatol, 9 (2), 137-44
DOI 10.1016/j.cgh.2010.10.012, PubMed 21029790

Gu F, Schumacher FR, Canzian F, Allen NE, Albanes D, Berg CD, Berndt SI, Boeing H, Bueno-de-Mesquita HB, Buring JE, Chabbert-Buffet N, Chanock SJ, Clavel-Chapelon F, Dumeaux V, Gaziano JM, Giovannucci EL, Haiman CA, Hankinson SE, Hayes RB, Henderson BE, Hunter DJ, Hoover RN, Johansson M, Key TJ, Khaw KT et al. (2010)
Eighteen insulin-like growth factor pathway genes, circulating levels of IGF-I and its binding protein, and risk of prostate and breast cancer
Cancer Epidemiol Biomarkers Prev, 19 (11), 2877-87
DOI 10.1158/1055-9965.EPI-10-0507, PubMed 20810604

Dossus L, Allen N, Kaaks R, Bakken K, Lund E, Tjonneland A, Olsen A, Overvad K, Clavel-Chapelon F, Fournier A, Chabbert-Buffet N, Boeing H, Schütze M, Trichopoulou A, Trichopoulos D, Lagiou P, Palli D, Krogh V, Tumino R, Vineis P, Mattiello A, Bueno-de-Mesquita HB, Onland-Moret NC, Peeters PH, Dumeaux V et al. (2010)
Reproductive risk factors and endometrial cancer: the European Prospective Investigation into Cancer and Nutrition
Int J Cancer, 127 (2), 442-51
DOI 10.1002/ijc.25050, PubMed 19924816

Landmark-Høyvik H, Reinertsen KV, Loge JH, Kristensen VN, Dumeaux V, Fosså SD, Børresen-Dale AL, Edvardsen H (2010)
The genetics and epigenetics of fatigue
PM R, 2 (5), 456-65
DOI 10.1016/j.pmrj.2010.04.003, PubMed 20656628

Rinaldi S, Cleveland R, Norat T, Biessy C, Rohrmann S, Linseisen J, Boeing H, Pischon T, Panico S, Agnoli C, Palli D, Tumino R, Vineis P, Peeters PH, van Gils CH, Bueno-de-Mesquita BH, Vrieling A, Allen NE, Roddam A, Bingham S, Khaw KT, Manjer J, Borgquist S, Dumeaux V, Torhild Gram I et al. (2010)
Serum levels of IGF-I, IGFBP-3 and colorectal cancer risk: results from the EPIC cohort, plus a meta-analysis of prospective studies
Int J Cancer, 126 (7), 1702-15
DOI 10.1002/ijc.24927, PubMed 19810099

Dumeaux V, Olsen KS, Nuel G, Paulssen RH, Børresen-Dale AL, Lund E (2010)
Deciphering normal blood gene expression variation--The NOWAC postgenome study
PLoS Genet, 6 (3), e1000873
DOI 10.1371/journal.pgen.1000873, PubMed 20300640

Aarøe J, Lindahl T, Dumeaux V, Saebø S, Tobin D, Hagen N, Skaane P, Lönneborg A, Sharma P, Børresen-Dale AL (2010)
Gene expression profiling of peripheral blood cells for early detection of breast cancer
Breast Cancer Res, 12 (1), R7
DOI 10.1186/bcr2472, PubMed 20078854

Hoeft B, Linseisen J, Beckmann L, Müller-Decker K, Canzian F, Hüsing A, Kaaks R, Vogel U, Jakobsen MU, Overvad K, Hansen RD, Knüppel S, Boeing H, Trichopoulou A, Koumantaki Y, Trichopoulos D, Berrino F, Palli D, Panico S, Tumino R, Bueno-de-Mesquita HB, van Duijnhoven FJ, van Gils CH, Peeters PH, Dumeaux V et al. (2009)
Polymorphisms in fatty-acid-metabolism-related genes are associated with colorectal cancer risk
Carcinogenesis, 31 (3), 466-72
DOI 10.1093/carcin/bgp325, PubMed 20042636

Landmark-Høyvik H, Reinertsen KV, Loge JH, Fosså SD, Børresen-Dale AL, Dumeaux V (2009)
Alterations of gene expression in blood cells associated with chronic fatigue in breast cancer survivors
Pharmacogenomics J, 9 (5), 333-40
DOI 10.1038/tpj.2009.27, PubMed 19546881

Huttenhower C, Haley EM, Hibbs MA, Dumeaux V, Barrett DR, Coller HA, Troyanskaya OG (2009)
Exploring the human genome with functional maps
Genome Res, 19 (6), 1093-106
DOI 10.1101/gr.082214.108, PubMed 19246570

Barutcuoglu Z, Airoldi EM, Dumeaux V, Schapire RE, Troyanskaya OG (2008)
Aneuploidy prediction and tumor classification with heterogeneous hidden conditional random fields
Bioinformatics, 25 (10), 1307-13
DOI 10.1093/bioinformatics/btn585, PubMed 19052061

Lund E, Dumeaux V (2008)
Systems epidemiology in cancer
Cancer Epidemiol Biomarkers Prev, 17 (11), 2954-7
DOI 10.1158/1055-9965.EPI-08-0519, PubMed 18990736

Dumeaux V, Lund E, Børresen-Dale AL (2008)
Comparison of globin RNA processing methods for genome-wide transcriptome analysis from whole blood
Biomark Med, 2 (1), 11-21
DOI 10.2217/17520363.2.1.11, PubMed 20477359

Waaseth M, Bakken K, Dumeaux V, Olsen KS, Rylander C, Figenschau Y, Lund E (2008)
Hormone replacement therapy use and plasma levels of sex hormones in the Norwegian Women and Cancer postgenome cohort - a cross-sectional analysis
BMC Womens Health, 8, 1
DOI 10.1186/1472-6874-8-1, PubMed 18194511

Dumeaux V, Børresen-Dale AL, Frantzen JO, Kumle M, Kristensen VN, Lund E (2008)
Gene expression analyses in breast cancer epidemiology: the Norwegian Women and Cancer postgenome cohort study
Breast Cancer Res, 10 (1), R13
DOI 10.1186/bcr1859, PubMed 18271962

Lund E, Bakken K, Dumeaux V, Andersen V, Kumle M (2007)
Hormone replacement therapy and breast cancer in former users of oral contraceptives--The Norwegian Women and Cancer study
Int J Cancer, 121 (3), 645-8
DOI 10.1002/ijc.22699, PubMed 17372914

Lund E, Dumeaux V, Braaten T, Hjartåker A, Engeset D, Skeie G, Kumle M (2007)
Cohort profile: The Norwegian Women and Cancer Study--NOWAC--Kvinner og kreft
Int J Epidemiol, 37 (1), 36-41
DOI 10.1093/ije/dym137, PubMed 17644530

Dumeaux V, Johansen J, Børresen-Dale AL, Lund E (2006)
Gene expression profiling of whole-blood samples from women exposed to hormone replacement therapy
Mol Cancer Ther, 5 (4), 868-76
DOI 10.1158/1535-7163.MCT-05-0329, PubMed 16648556

Kringen P, Wang Y, Dumeaux V, Nesland JM, Kristensen G, Borresen-Dale AL, Dorum A (2005)
TP53 mutations in ovarian carcinomas from sporadic cases and carriers of two distinct BRCA1 founder mutations; relation to age at diagnosis and survival
BMC Cancer, 5, 134
DOI 10.1186/1471-2407-5-134, PubMed 16229746

Dumeaux V, Fournier A, Lund E, Clavel-Chapelon F (2005)
Previous oral contraceptive use and breast cancer risk according to hormone replacement therapy use among postmenopausal women
Cancer Causes Control, 16 (5), 537-44
DOI 10.1007/s10552-004-8024-z, PubMed 15986108

Dumeaux V, Lund E, Hjartåker A (2004)
Use of oral contraceptives, alcohol, and risk for invasive breast cancer
Cancer Epidemiol Biomarkers Prev, 13 (8), 1302-7
PubMed 15298950

Dumeaux V, Alsaker E, Lund E (2003)
Breast cancer and specific types of oral contraceptives: a large Norwegian cohort study
Int J Cancer, 105 (6), 844-50
DOI 10.1002/ijc.11167, PubMed 12767072

Review articles

Lund E, Dumeaux V (2010)
Towards a more functional concept of causality in cancer research
Int J Mol Epidemiol Genet, 1 (2), 124-33
PubMed 21537385

Lönneborg A, Aarøe J, Dumeaux V, Børresen-Dale AL (2009)
Found in transcription: gene expression and other novel blood biomarkers for the early detection of breast cancer
Expert Rev Anticancer Ther, 9 (8), 1115-23
DOI 10.1586/era.09.31, PubMed 19671031

Theses

Dumeaux V (2005)
Exposure to exogenous hormones in women: risk factors for breast cancer and molecular signature
In ISM skriftserie, Universitetet i Tromsø, Institutt for samfunnsmedisin, Tromsø, nr 82, 1 b. (flere pag.)
BIBSYS 052159507, ISBN 82-90262-92-2