Publications by Arne Klungland
157 publications found
Original articles
Depletion of the m1A writer TRMT6/TRMT61A reduces proliferation and resistance against cellular stress in bladder cancer
Front Oncol, 13, 1334112
DOI 10.3389/fonc.2023.1334112, PubMed 38304034
CDK12/CDK13 inhibition disrupts a transcriptional program critical for glioblastoma survival
BioRxiv, 2023, 110-113
DOI 10.1101/2023.07.14.548985v1, PublikaID 442
Single-cell m6A mapping in vivo using picoMeRIP-seq
Nat Biotechnol, 42 (4), 591-596
DOI 10.1038/s41587-023-01831-7, PubMed 37349523
The RNA m6A landscape of mouse oocytes and preimplantation embryos
Nat Struct Mol Biol, 30 (5), 703-709
DOI 10.1038/s41594-023-00969-x, PubMed 37081317
Mechanical coupling of supracellular stress amplification and tissue fluidization during exit from quiescence
Proc Natl Acad Sci U S A, 119 (32), e2201328119
DOI 10.1073/pnas.2201328119, PubMed 35914175
Characterization of novel small non-coding RNAs and their modifications in bladder cancer using an updated small RNA-seq workflow
Front Mol Biosci, 9, 887686
DOI 10.3389/fmolb.2022.887686, PubMed 35923465
ALKBH5 regulates somatic cell reprogramming in a phase-specific manner
J Cell Sci, 135 (11)
DOI 10.1242/jcs.259824, PubMed 35552718
TRMT6/61A-dependent base methylation of tRNA-derived fragments regulates gene-silencing activity and the unfolded protein response in bladder cancer
Nat Commun, 13 (1), 2165
DOI 10.1038/s41467-022-29790-8, PubMed 35444240
Waves of sumoylation support transcription dynamics during adipocyte differentiation
Nucleic Acids Res, 50 (3), 1351-1369
DOI 10.1093/nar/gkac027, PubMed 35100417
Intrinsic Strand-Incision Activity of Human UNG: Implications for Nick Generation in Immunoglobulin Gene Diversification
Front Immunol, 12, 762032
DOI 10.3389/fimmu.2021.762032, PubMed 35003074
N6-methyladenosine (m6A) depletion regulates pluripotency exit by activating signaling pathways in embryonic stem cells
Proc Natl Acad Sci U S A, 118 (51)
DOI 10.1073/pnas.2105192118, PubMed 34921114
NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice
Commun Biol, 4 (1), 1354
DOI 10.1038/s42003-021-02864-x, PubMed 34857879
ALKBH7-mediated demethylation regulates mitochondrial polycistronic RNA processing
Nat Cell Biol, 23 (7), 684-691
DOI 10.1038/s41556-021-00709-7, PubMed 34253897
Alleviation of C⋅C Mismatches in DNA by the Escherichia coli Fpg Protein
Front Microbiol, 12, 608839
DOI 10.3389/fmicb.2021.608839, PubMed 34276575
Modifications and interactions at the R-loop
DNA Repair (Amst), 96, 102958
DOI 10.1016/j.dnarep.2020.102958, PubMed 32961406
Deletion of Endonuclease V suppresses chemically induced hepatocellular carcinoma
Nucleic Acids Res, 48 (8), 4463-4479
DOI 10.1093/nar/gkaa115, PubMed 32083667
KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes
Nat Cell Biol, 22 (4), 380-388
DOI 10.1038/s41556-020-0494-z, PubMed 32231309
OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation
Cell Rep, 30 (12), 4165-4178.e7
DOI 10.1016/j.celrep.2020.02.063, PubMed 32209476
The Escherichia coli alkA Gene Is Activated to Alleviate Mutagenesis by an Oxidized Deoxynucleoside
Front Microbiol, 11, 263
DOI 10.3389/fmicb.2020.00263, PubMed 32158436
N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells
Nat Genet, 52 (1), 48-55
DOI 10.1038/s41588-019-0549-x, PubMed 31844323
Histone Methylations Define Neural Stem/Progenitor Cell Subtypes in the Mouse Subventricular Zone
Mol Neurobiol, 57 (2), 997-1008
DOI 10.1007/s12035-019-01777-5, PubMed 31654318
ALKBH overexpression in head and neck cancer: potential target for novel anticancer therapy
Sci Rep, 9 (1), 13249
DOI 10.1038/s41598-019-49550-x, PubMed 31519943
5-hydroxymethylcytosine Marks Mammalian Origins Acting as a Barrier to Replication
Sci Rep, 9 (1), 11065
DOI 10.1038/s41598-019-47528-3, PubMed 31363131
Excision of uracil from DNA by hSMUG1 includes strand incision and processing
Nucleic Acids Res, 47 (2), 779-793
DOI 10.1093/nar/gky1184, PubMed 30496516
A transgenic minipig model of Huntington's disease shows early signs of behavioral and molecular pathologies
Dis Model Mech, 11 (10)
DOI 10.1242/dmm.035949, PubMed 30254085
STIM1 R304W causes muscle degeneration and impaired platelet activation in mice
Cell Calcium, 76, 87-100
DOI 10.1016/j.ceca.2018.10.001, PubMed 30390422
Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm
Mol Cell, 71 (6), 973-985.e5
DOI 10.1016/j.molcel.2018.08.011, PubMed 30197295
Increased nuclear DNA damage precedes mitochondrial dysfunction in peripheral blood mononuclear cells from Huntington's disease patients
Sci Rep, 8 (1), 9817
DOI 10.1038/s41598-018-27985-y, PubMed 29959348
Excision of the doubly methylated base N4,5-dimethylcytosine from DNA by Escherichia coli Nei and Fpg proteins
Philos Trans R Soc Lond B Biol Sci, 373 (1748)
DOI 10.1098/rstb.2017.0337, PubMed 29685966
Ythdf2-mediated m6A mRNA clearance modulates neural development in mice
Genome Biol, 19 (1), 69
DOI 10.1186/s13059-018-1436-y, PubMed 29855337
RNA m6A methylation participates in regulation of postnatal development of the mouse cerebellum
Genome Biol, 19 (1), 68
DOI 10.1186/s13059-018-1435-z, PubMed 29855379
ALKBH5-dependent m6A demethylation controls splicing and stability of long 3'-UTR mRNAs in male germ cells
Proc Natl Acad Sci U S A, 115 (2), E325-E333
DOI 10.1073/pnas.1717794115, PubMed 29279410
Metabolism and DNA repair shape a specific modification pattern in mitochondrial DNA
Mitochondrion, 40, 16-28
DOI 10.1016/j.mito.2017.09.002, PubMed 28893634
Role of the DNA repair glycosylase OGG1 in the activation of murine splenocytes
DNA Repair (Amst), 58, 13-20
DOI 10.1016/j.dnarep.2017.08.005, PubMed 28843610
ALKBH7 drives a tissue and sex-specific necrotic cell death response following alkylation-induced damage
Cell Death Dis, 8 (7), e2947
DOI 10.1038/cddis.2017.343, PubMed 28726787
No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient mice
Sci Rep, 7 (1), 4384
DOI 10.1038/s41598-017-04472-4, PubMed 28663564
Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation
Cell Discov, 3, 17013
DOI 10.1038/celldisc.2017.13, PubMed 28529766
Nucleocytoplasmic Shuttling of FTO Does Not Affect Starvation-Induced Autophagy
PLoS One, 12 (3), e0168182
DOI 10.1371/journal.pone.0168182, PubMed 28288181
Gene expression profiles in preterm infants on continuous long‑term oxygen therapy suggest reduced oxidative stress‑dependent signaling during hypoxia
Mol Med Rep, 15 (4), 1513-1526
DOI 10.3892/mmr.2017.6185, PubMed 28259955
Corrigendum: Sumoylation of Rap1 mediates the recruitment of TFIID to promote transcription of ribosomal protein genes
Genome Res, 27 (2), 334
DOI 10.1101/gr.218370.116, PubMed 28148563
TORC1-dependent sumoylation of Rpc82 promotes RNA polymerase III assembly and activity
Proc Natl Acad Sci U S A, 114 (5), 1039-1044
DOI 10.1073/pnas.1615093114, PubMed 28096404
NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture
Cell Rep, 18 (1), 82-92
DOI 10.1016/j.celrep.2016.12.009, PubMed 28052262
Reversible RNA modifications in meiosis and pluripotency
Nat Methods, 14 (1), 18-22
DOI 10.1038/nmeth.4111, PubMed 28032624
ALKBH1-Mediated tRNA Demethylation Regulates Translation
Cell, 167 (7), 1897
DOI 10.1016/j.cell.2016.11.045, PubMed 27984735
Removal of aquaporin-4 from glial and ependymal membranes causes brain water accumulation
Mol Cell Neurosci, 77, 47-52
DOI 10.1016/j.mcn.2016.10.004, PubMed 27751903
ALKBH1-Mediated tRNA Demethylation Regulates Translation
Cell, 167 (3), 816-828.e16
DOI 10.1016/j.cell.2016.09.038, PubMed 27745969
Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition
Nature, 537 (7621), 548-552
DOI 10.1038/nature19360, PubMed 27626377
A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain
Neurobiol Aging, 48, 34-47
DOI 10.1016/j.neurobiolaging.2016.08.005, PubMed 27639119
Effects of Anthocyanins on CAG Repeat Instability and Behaviour in Huntington's Disease R6/1 Mice
PLoS Curr, 8
DOI 10.1371/currents.hd.58d04209ab6d5de0844db7ef5628ff67, PubMed 27540492
Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells
Epigenetics Chromatin, 9, 21
DOI 10.1186/s13072-016-0070-8, PubMed 27252783
Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism
Nat Commun, 7, 10806
DOI 10.1038/ncomms10806, PubMed 26932196
DNA base modifications in honey bee and fruit fly genomes suggest an active demethylation machinery with species- and tissue-specific turnover rates
Biochem Biophys Rep, 6, 9-15
DOI 10.1016/j.bbrep.2016.02.011, PubMed 28955859
DNA base modifications in honey bee and fruit fly genomes suggest an active demethylation machinery with species- and tissue-specific turnover rates
Biochemistry and Biophysics Reports, 6, 9-15
DOI 10.1016/j.bbrep.2016.02.011, PublikaID 234
Sequencing of FTO and ALKBH5 in men undergoing infertility work-up identifies an infertility-associated variant and two missense mutations
Fertil Steril, 105 (5), 1170-1179.e5
DOI 10.1016/j.fertnstert.2016.01.002, PubMed 26820768
Role of ALKBH1 in the Core Transcriptional Network of Embryonic Stem Cells
Cell Physiol Biochem, 38 (1), 173-84
DOI 10.1159/000438619, PubMed 26765775
Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice
Cell Rep, 13 (12), 2671-8
DOI 10.1016/j.celrep.2015.12.001, PubMed 26711335
Base-excision repair and beyond —A short summary attributed to scientific achievements of Tomas Lindahl, Nobel Prize Laureate in Chemistry 2015
Science China Life Sciences, 59 (1), 89-92
DOI 10.1007/s11427-015-4983-4, PublikaID 237
Lysine Methylation of the Valosin-Containing Protein (VCP) Is Dispensable for Development and Survival of Mice
PLoS One, 10 (11), e0141472
DOI 10.1371/journal.pone.0141472, PubMed 26544960
A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation
Genes Dev, 29 (19), 2037-53
DOI 10.1101/gad.269415.115, PubMed 26404942
Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure
Am J Physiol Heart Circ Physiol, 309 (3), H434-49
DOI 10.1152/ajpheart.00253.2014, PubMed 26055793
Sumoylation of Rap1 mediates the recruitment of TFIID to promote transcription of ribosomal protein genes
Genome Res, 25 (6), 897-906
DOI 10.1101/gr.185793.114, PubMed 25800674
Micro chromatin immunoprecipitation (μChIP) from early mammalian embryos
Methods Mol Biol, 1222, 227-45
DOI 10.1007/978-1-4939-1594-1_17, PubMed 25287350
Endonuclease G preferentially cleaves 5-hydroxymethylcytosine-modified DNA creating a substrate for recombination
Nucleic Acids Res, 42 (21), 13280-93
DOI 10.1093/nar/gku1032, PubMed 25355512
ALKBH4 depletion in mice leads to spermatogenic defects
PLoS One, 9 (8), e105113
DOI 10.1371/journal.pone.0105113, PubMed 25153837
Protozoan ALKBH8 oxygenases display both DNA repair and tRNA modification activities
PLoS One, 9 (6), e98729
DOI 10.1371/journal.pone.0098729, PubMed 24914785
Dynamic RNA modifications in disease
Curr Opin Genet Dev, 26, 47-52
DOI 10.1016/j.gde.2014.05.006, PubMed 25005745
Oxidative stress causes DNA triplet expansion in Huntington's disease mouse embryonic stem cells
Stem Cell Res, 11 (3), 1264-71
DOI 10.1016/j.scr.2013.08.010, PubMed 24041806
Deletion of mouse Alkbh7 leads to obesity
J Mol Cell Biol, 5 (3), 194-203
DOI 10.1093/jmcb/mjt012, PubMed 23572141
Tzfp represses the androgen receptor in mouse testis
PLoS One, 8 (4), e62314
DOI 10.1371/journal.pone.0062314, PubMed 23634227
ALKBH4-dependent demethylation of actin regulates actomyosin dynamics
Nat Commun, 4, 1832
DOI 10.1038/ncomms2863, PubMed 23673617
ALKBH1 is a histone H2A dioxygenase involved in neural differentiation
Stem Cells, 30 (12), 2672-82
DOI 10.1002/stem.1228, PubMed 22961808
ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility
Mol Cell, 49 (1), 18-29
DOI 10.1016/j.molcel.2012.10.015, PubMed 23177736
Alkbh1 and Tzfp repress a non-repeat piRNA cluster in pachytene spermatocytes
Nucleic Acids Res, 40 (21), 10950-63
DOI 10.1093/nar/gks839, PubMed 22965116
Neil1 is a genetic modifier of somatic and germline CAG trinucleotide repeat instability in R6/1 mice
Hum Mol Genet, 21 (22), 4939-47
DOI 10.1093/hmg/dds337, PubMed 22914735
Kinetics of endogenous mouse FEN1 in base excision repair
Nucleic Acids Res, 40 (18), 9044-59
DOI 10.1093/nar/gks673, PubMed 22810208
DNA repair is indispensable for survival after acute inflammation
J Clin Invest, 122 (7), 2680-9
DOI 10.1172/JCI63338, PubMed 22684101
The DNA dioxygenase ALKBH2 protects Arabidopsis thaliana against methylation damage
Nucleic Acids Res, 40 (14), 6620-31
DOI 10.1093/nar/gks327, PubMed 22532610
Pull-down of 5-hydroxymethylcytosine DNA using JBP1-coated magnetic beads
Nat Protoc, 7 (2), 340-50
DOI 10.1038/nprot.2011.443, PubMed 22281869
Glial-conditional deletion of aquaporin-4 (Aqp4) reduces blood-brain water uptake and confers barrier function on perivascular astrocyte endfeet
Proc Natl Acad Sci U S A, 108 (43), 17815-20
DOI 10.1073/pnas.1110655108, PubMed 21990350
X-linked Angelman-like syndrome caused by Slc9a6 knockout in mice exhibits evidence of endosomal-lysosomal dysfunction
Brain, 134 (Pt 11), 3369-83
DOI 10.1093/brain/awr250, PubMed 21964919
Evidence that compromised K+ spatial buffering contributes to the epileptogenic effect of mutations in the human Kir4.1 gene (KCNJ10)
Glia, 59 (11), 1635-42
DOI 10.1002/glia.21205, PubMed 21748805
The presence of 5-hydroxymethylcytosine at the gene promoter and not in the gene body negatively regulates gene expression
Biochem Biophys Res Commun, 411 (1), 40-3
DOI 10.1016/j.bbrc.2011.06.077, PubMed 21703242
Uracil-DNA glycosylase of Thermoplasma acidophilum directs long-patch base excision repair, which is promoted by deoxynucleoside triphosphates and ATP/ADP, into short-patch repair
J Bacteriol, 193 (17), 4495-508
DOI 10.1128/JB.00233-11, PubMed 21665970
Mitochondrial DNA toxicity compromises mitochondrial dynamics and induces hippocampal antioxidant defenses
DNA Repair (Amst), 10 (6), 639-53
DOI 10.1016/j.dnarep.2011.04.011, PubMed 21550321
Modeling the impact of mitochondrial DNA damage in forebrain neurons and beyond
Mech Ageing Dev, 132 (8-9), 424-8
DOI 10.1016/j.mad.2011.02.006, PubMed 21354441
A novel method for the efficient and selective identification of 5-hydroxymethylcytosine in genomic DNA
Nucleic Acids Res, 39 (8), e55
DOI 10.1093/nar/gkr051, PubMed 21300643
ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA
Nat Commun, 2, 172
DOI 10.1038/ncomms1173, PubMed 21285950
Critical role of aquaporin-4 (AQP4) in astrocytic Ca2+ signaling events elicited by cerebral edema
Proc Natl Acad Sci U S A, 108 (2), 846-51
DOI 10.1073/pnas.1015217108, PubMed 21187412
Continuous and periodic expansion of CAG repeats in Huntington's disease R6/1 mice
PLoS Genet, 6 (12), e1001242
DOI 10.1371/journal.pgen.1001242, PubMed 21170307
Spontaneous mutagenesis in Csb(m/m)Ogg1⁻(/)⁻ mice is attenuated by dietary resveratrol
Carcinogenesis, 32 (1), 80-5
DOI 10.1093/carcin/bgq196, PubMed 21062970
Mice lacking Alkbh1 display sex-ratio distortion and unilateral eye defects
PLoS One, 5 (11), e13827
DOI 10.1371/journal.pone.0013827, PubMed 21072209
The hyperthermophilic euryarchaeon Archaeoglobus fulgidus repairs uracil by single-nucleotide replacement
J Bacteriol, 192 (21), 5755-66
DOI 10.1128/JB.00135-10, PubMed 20453094
Histone H3 lysine 27 methylation asymmetry on developmentally-regulated promoters distinguish the first two lineages in mouse preimplantation embryos
PLoS One, 5 (2), e9150
DOI 10.1371/journal.pone.0009150, PubMed 20161773
Mammalian ALKBH8 possesses tRNA methyltransferase activity required for the biogenesis of multiple wobble uridine modifications implicated in translational decoding
Mol Cell Biol, 30 (7), 1814-27
DOI 10.1128/MCB.01602-09, PubMed 20123966
Mitochondrial DNA toxicity in forebrain neurons causes apoptosis, neurodegeneration, and impaired behavior
Mol Cell Biol, 30 (6), 1357-67
DOI 10.1128/MCB.01149-09, PubMed 20065039
Bioinformatics and functional analysis define four distinct groups of AlkB DNA-dioxygenases in bacteria
Nucleic Acids Res, 37 (21), 7124-36
DOI 10.1093/nar/gkp774, PubMed 19786499
8-Oxoguanine-mediated transcriptional mutagenesis causes Ras activation in mammalian cells
Proc Natl Acad Sci U S A, 105 (48), 18877-82
DOI 10.1073/pnas.0806464105, PubMed 19020090
Early-onset lymphoma and extensive embryonic apoptosis in two domain-specific Fen1 mice mutants
Cancer Res, 68 (12), 4571-9
DOI 10.1158/0008-5472.CAN-08-0168, PubMed 18559501
AlkB homologue 2-mediated repair of ethenoadenine lesions in mammalian DNA
Cancer Res, 68 (11), 4142-9
DOI 10.1158/0008-5472.CAN-08-0796, PubMed 18519673
Mutations in the RAD27 and SGS1 genes differentially affect the chronological and replicative lifespan of yeast cells growing on glucose and glycerol
FEMS Yeast Res, 7 (6), 848-59
DOI 10.1111/j.1567-1364.2007.00248.x, PubMed 17506834
OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells
Nature, 447 (7143), 447-52
DOI 10.1038/nature05778, PubMed 17450122
Structural basis for enzymatic excision of N1-methyladenine and N3-methylcytosine from DNA
EMBO J, 26 (8), 2206-17
DOI 10.1038/sj.emboj.7601662, PubMed 17396151
Repeated inhalations of diesel exhaust particles and oxidatively damaged DNA in young oxoguanine DNA glycosylase (OGG1) deficient mice
Free Radic Res, 41 (2), 172-81
DOI 10.1080/10715760601024122, PubMed 17364943
Genome instability and DNA damage accumulation in gene-targeted mice
Neuroscience, 145 (4), 1309-17
DOI 10.1016/j.neuroscience.2006.10.059, PubMed 17218062
Deficiency of the Cockayne syndrome B (CSB) gene aggravates the genomic instability caused by endogenous oxidative DNA base damage in mice
Oncogene, 26 (27), 4044-8
DOI 10.1038/sj.onc.1210167, PubMed 17213818
Repair of methyl lesions in DNA and RNA by oxidative demethylation
Neuroscience, 145 (4), 1222-32
DOI 10.1016/j.neuroscience.2006.11.018, PubMed 17175108
Oxidative damage to purines in DNA: role of mammalian Ogg1
DNA Repair (Amst), 6 (4), 481-8
DOI 10.1016/j.dnarep.2006.10.012, PubMed 17127104
A novel splice site mutation in the Cockayne syndrome group A gene in two siblings with Cockayne syndrome
Neuroscience, 145 (4), 1397-406
DOI 10.1016/j.neuroscience.2006.09.025, PubMed 17084038
Deficiency in OGG1 protects against inflammation and mutagenic effects associated with H. pylori infection in mouse
Helicobacter, 11 (5), 494-505
DOI 10.1111/j.1523-5378.2006.00442.x, PubMed 16961812
Repair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNA
EMBO J, 25 (10), 2189-98
DOI 10.1038/sj.emboj.7601109, PubMed 16642038
Repair and mutagenesis at oxidized DNA lesions in the developing brain of wild-type and Ogg1-/- mice
Oncogene, 25 (17), 2425-32
DOI 10.1038/sj.onc.1209284, PubMed 16369492
Substantial decrease of urinary 8-oxo-7,8-dihydroguanine, a product of the base excision repair pathway, in DNA glycosylase defective mice
Int J Biochem Cell Biol, 37 (6), 1331-6
DOI 10.1016/j.biocel.2005.01.001, PubMed 15778095
Tolerated wobble mutations in siRNAs decrease specificity, but can enhance activity in vivo
Nucleic Acids Res, 33 (15), 4704-10
DOI 10.1093/nar/gki785, PubMed 16113241
Transcription activities at 8-oxoG lesions in DNA
DNA Repair (Amst), 3 (11), 1457-68
DOI 10.1016/j.dnarep.2004.06.008, PubMed 15380101
Diet is not responsible for the presence of several oxidatively damaged DNA lesions in mouse urine
Free Radic Res, 38 (11), 1201-5
DOI 10.1080/10715760400017350, PubMed 15621697
Urinary excretion of DNA repair products correlates with metabolic rates as well as with maximum life spans of different mammalian species
Free Radic Biol Med, 37 (9), 1449-54
DOI 10.1016/j.freeradbiomed.2004.07.014, PubMed 15454284
Better late than never for repair of miscoding lesions within a transcribed template
Mol Cell, 12 (4), 799-800
DOI 10.1016/s1097-2765(03)00403-9, PubMed 14580331
Proliferation failure and gamma radiation sensitivity of Fen1 null mutant mice at the blastocyst stage
Mol Cell Biol, 23 (15), 5346-53
DOI 10.1128/MCB.23.15.5346-5353.2003, PubMed 12861020
Reversible inactivation of E. coli endonuclease III via modification of its [4Fe-4S] cluster by nitric oxide
DNA Repair (Amst), 2 (7), 809-17
DOI 10.1016/s1568-7864(03)00065-x, PubMed 12826281
Incision at hypoxanthine residues in DNA by a mammalian homologue of the Escherichia coli antimutator enzyme endonuclease V
Nucleic Acids Res, 31 (14), 3893-900
DOI 10.1093/nar/gkg472, PubMed 12853604
Comparative analysis of 8-oxoG:C, 8-oxoG:A, A:C and C:C DNA repair in extracts from wild type or 8-oxoG DNA glycosylase deficient mammalian and bacterial cells
DNA Repair (Amst), 2 (6), 707-18
DOI 10.1016/s1568-7864(03)00041-7, PubMed 12767349
A global DNA repair mechanism involving the Cockayne syndrome B (CSB) gene product can prevent the in vivo accumulation of endogenous oxidative DNA base damage
Oncogene, 21 (54), 8232-9
DOI 10.1038/sj.onc.1206027, PubMed 12447686
Methylpurine DNA glycosylase of the hyperthermophilic archaeon Archaeoglobus fulgidus
Biochemistry, 41 (42), 12697-705
DOI 10.1021/bi020334w, PubMed 12379112
Excision of uracil from DNA by the hyperthermophilic Afung protein is dependent on the opposite base and stimulated by heat-induced transition to a more open structure
Mutat Res, 487 (3-4), 173-90
DOI 10.1016/s0921-8777(01)00115-x, PubMed 11738943
Repair of 8-oxodeoxyguanosine lesions in mitochondrial dna depends on the oxoguanine dna glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial dna of OGG1-defective mice
Cancer Res, 61 (14), 5378-81
PubMed 11454679
5-Formyluracil and its nucleoside derivatives confer toxicity and mutagenicity to mammalian cells by interfering with normal RNA and DNA metabolism
Toxicol Lett, 119 (1), 71-8
DOI 10.1016/s0378-4274(00)00308-8, PubMed 11275423
[Life without DNA repair]
Tidsskr Nor Laegeforen, 121 (1), 41-9
PubMed 12013614
Transcription coupled repair of 8-oxoguanine in murine cells: the ogg1 protein is required for repair in nontranscribed sequences but not in transcribed sequences
Proc Natl Acad Sci U S A, 97 (15), 8397-402
DOI 10.1073/pnas.140137297, PubMed 10890888
Base removers and strand scissors: different strategies employed in base excision and strand incision at modified base residues in DNA
Cold Spring Harb Symp Quant Biol, 65, 135-42
DOI 10.1101/sqb.2000.65.135, PubMed 12760028
Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage
Proc Natl Acad Sci U S A, 96 (23), 13300-5
DOI 10.1073/pnas.96.23.13300, PubMed 10557315
Base excision repair of oxidative DNA damage activated by XPG protein
Mol Cell, 3 (1), 33-42
DOI 10.1016/s1097-2765(00)80172-0, PubMed 10024877
Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase
Proc Natl Acad Sci U S A, 94 (15), 8016-20
DOI 10.1073/pnas.94.15.8016, PubMed 9223306
Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1)
EMBO J, 16 (11), 3341-8
DOI 10.1093/emboj/16.11.3341, PubMed 9214649
Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein
EMBO J, 15 (23), 6662-70
PubMed 8978692
Spectrum of mutations induced by methyl and ethyl methanesulfonate at the hprt locus of normal and tag expressing Chinese hamster fibroblasts
Carcinogenesis, 16 (6), 1281-5
DOI 10.1093/carcin/16.6.1281, PubMed 7788844
Purification and properties of the alkylation repair DNA glycosylase encoded the MAG gene from Saccharomyces cerevisiae
Biochemistry, 34 (14), 4577-82
DOI 10.1021/bi00014a010, PubMed 7718559
Increased removal of 3-alkyladenine reduces the frequencies of hprt mutations induced by methyl- and ethylmethanesulfonate in Chinese hamster fibroblast cells
Nucleic Acids Res, 22 (9), 1670-4
DOI 10.1093/nar/22.9.1670, PubMed 8202370
Expression of the E.coli 3-methyladenine DNA glycosylase I gene in mammalian cells reduces the toxic and mutagenic effects of methylating agents
EMBO J, 11 (12), 4439-44
DOI 10.1002/j.1460-2075.1992.tb05544.x, PubMed 1425578
Review articles
RNA m6A modifications in mammalian gametogenesis and pregnancy
Reproduction, 165 (1), R1-R8
DOI 10.1530/REP-22-0112, PubMed 36194446
"Too much guts and not enough brains": (epi)genetic mechanisms and future therapies of Hirschsprung disease - a review
Clin Epigenetics, 11 (1), 135
DOI 10.1186/s13148-019-0718-x, PubMed 31519213
Oxidized C5-methyl cytosine bases in DNA: 5-Hydroxymethylcytosine; 5-formylcytosine; and 5-carboxycytosine
Free Radic Biol Med, 107, 62-68
DOI 10.1016/j.freeradbiomed.2016.11.038, PubMed 27890639
ALKBHs-facilitated RNA modifications and de-modifications
DNA Repair (Amst), 44, 87-91
DOI 10.1016/j.dnarep.2016.05.026, PubMed 27237585
Non-homologous functions of the AlkB homologs
J Mol Cell Biol, 7 (6), 494-504
DOI 10.1093/jmcb/mjv029, PubMed 26003568
DNA repair in mammalian cells: Base excision repair: the long and short of it
Cell Mol Life Sci, 66 (6), 981-93
DOI 10.1007/s00018-009-8736-z, PubMed 19153658
Organ and cell specificity of base excision repair mutants in mice
Mutat Res, 614 (1-2), 56-68
DOI 10.1016/j.mrfmmm.2006.01.023, PubMed 16765995
Repair and processing events at DNA ends
Ciba Found Symp, 211, 198-205; discussion 205-8
DOI 10.1002/9780470515433.ch13, PubMed 9524759
Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks
Trends Biochem Sci, 20 (10), 405-11
DOI 10.1016/s0968-0004(00)89089-1, PubMed 8533153
Other articles
Studies on Protein-RNA:DNA Hybrid Interactions by Microscale Thermophoresis (MST)
Methods Mol Biol, 2528, 239-251
DOI 10.1007/978-1-0716-2477-7_15, PubMed 35704195
Positioning Europe for the EPITRANSCRIPTOMICS challenge
RNA Biol, 15 (6), 829-831
DOI 10.1080/15476286.2018.1460996, PubMed 29671387
Base-excision repair and beyond --A short summary attributed to scientific achievements of Tomas Lindahl, Nobel Prize Laureate in Chemistry 2015
Sci China Life Sci, 59 (1), 89-92
DOI 10.1007/s11427-015-4983-4, PubMed 26676642
Endogenous DNA Damage and Repair Enzymes: -A short summary of the scientific achievements of Tomas Lindahl, Nobel Laureate in Chemistry 2015
Genomics Proteomics Bioinformatics, 14 (3), 122-125
DOI 10.1016/j.gpb.2015.11.001, PubMed 26689322
DNA metabolism: bases of DNA repair and regulation
Nat Chem Biol, 10 (7), 487-8
DOI 10.1038/nchembio.1553, PubMed 24937064
Sprouts of RNA epigenetics: the discovery of mammalian RNA demethylases
RNA Biol, 10 (6), 915-8
DOI 10.4161/rna.24711, PubMed 23619745
[Nobel Prize for genetic modification]
Tidsskr Nor Laegeforen, 127 (23), 3054
PubMed 18049491
Book chapters
OGG1: From Structural Analysis to the Knockout Mouse
In Oxidative Damage to Nucleic Acids (Evans MD, Cooke MS, eds.), Landes Bioscience and Springer Science+Business Media, 67-80
DOI 10.1007/978-0-387-72974-9_5, PublikaID 44, ISBN 978-0-387-72973-2
Theses
Properties and biological effects of alkylbase DNA glycosylases
Norwegian Cancer Society : Biotechnology Centre of Oslo and Department of Biology, University of Oslo, Oslo, 1 b. (flere pag.)
BIBSYS 942916395, ISBN 82-91493-00-6
Virkning av gibrellinsyre (GA3) i normale og mutante byggfrø (Hordeum) vulgare L.) under spiring
A. Klungland, Oslo, 137 s.
BIBSYS 961060832