Publications by Guttorm Haraldsen
97 publications found
Original articles
Detection of native, activated Notch receptors in normal human apocrine-bearing skin and in hidradenitis suppurativa
Exp Dermatol, 33 (1), e14977
DOI 10.1111/exd.14977, PubMed 38060347
Antibody blockade of Jagged1 attenuates choroidal neovascularization
Nat Commun, 14 (1), 3109
DOI 10.1038/s41467-023-38563-w, PubMed 37253747
Hypo-osmotic stress induces the epithelial alarmin IL-33 in the colonic barrier of ulcerative colitis
Sci Rep, 12 (1), 11550
DOI 10.1038/s41598-022-15573-0, PubMed 35798804
A novel somatic mutation in GNB2 provides new insights to the pathogenesis of Sturge-Weber syndrome
Hum Mol Genet, 30 (21), 1919-1931
DOI 10.1093/hmg/ddab144, PubMed 34124757
Activated, Pro-Inflammatory Th1, Th17, and Memory CD4+ T Cells and B Cells Are Involved in Delayed-Type Hypersensitivity Arthritis (DTHA) Inflammation and Paw Swelling in Mice
Front Immunol, 12, 689057
DOI 10.3389/fimmu.2021.689057, PubMed 34408746
Inflammatory activation of endothelial cells increases glycolysis and oxygen consumption despite inhibiting cell proliferation
FEBS Open Bio, 11 (6), 1719-1730
DOI 10.1002/2211-5463.13174, PubMed 33979025
Shifts in the Skin Microbiota after UVB Treatment in Adult Atopic Dermatitis
Dermatology, 238 (1), 109-120
DOI 10.1159/000515236, PubMed 33887725
Rapid systemic surge of IL-33 after severe human trauma: a prospective observational study
Mol Med, 27 (1), 29
DOI 10.1186/s10020-021-00288-1, PubMed 33771098
Nuclear IL-33 restrains the early conversion of fibroblasts to an extracellular matrix-secreting phenotype
Sci Rep, 11 (1), 108
DOI 10.1038/s41598-020-80509-5, PubMed 33420328
Exploring the potential effect of paricalcitol on markers of inflammation in de novo renal transplant recipients
PLoS One, 15 (12), e0243759
DOI 10.1371/journal.pone.0243759, PubMed 33326471
Early transcriptional changes after UVB treatment in atopic dermatitis include inverse regulation of IL-36γ and IL-37
Exp Dermatol, 30 (2), 249-261
DOI 10.1111/exd.14217, PubMed 33067891
Lack of interleukin-33 and its receptor does not prevent calcipotriol-induced atopic dermatitis-like inflammation in mice
Sci Rep, 10 (1), 6451
DOI 10.1038/s41598-020-63410-z, PubMed 32296080
Interleukin-33 Signaling Controls the Development of Iron-Recycling Macrophages
Immunity, 52 (5), 782-793.e5
DOI 10.1016/j.immuni.2020.03.006, PubMed 32272082
3PO inhibits inflammatory NFκB and stress-activated kinase signaling in primary human endothelial cells independently of its target PFKFB3
PLoS One, 15 (3), e0229395
DOI 10.1371/journal.pone.0229395, PubMed 32130250
HMGB1 concentration measurements in trauma patients: assessment of pre-analytical conditions and sample material
Mol Med, 26 (1), 5
DOI 10.1186/s10020-019-0131-0, PubMed 31892315
Hypo-osmotic Stress Drives IL-33 Production in Human Keratinocytes-An Epidermal Homeostatic Response
J Invest Dermatol, 139 (1), 81-90
DOI 10.1016/j.jid.2018.07.023, PubMed 30120934
Inhibition of Endothelial NOTCH1 Signaling Attenuates Inflammation by Reducing Cytokine-Mediated Histone Acetylation at Inflammatory Enhancers
Arterioscler Thromb Vasc Biol, 38 (4), 854-869
DOI 10.1161/ATVBAHA.117.310388, PubMed 29449332
Early introduction of oral paricalcitol in renal transplant recipients. An open-label randomized study
Transpl Int, 30 (8), 827-840
DOI 10.1111/tri.12973, PubMed 28436117
Endothelial IL-33 Expression Is Augmented by Adenoviral Activation of the DNA Damage Machinery
J Immunol, 198 (8), 3318-3325
DOI 10.4049/jimmunol.1600054, PubMed 28258201
Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy
Cancer Cell, 30 (6), 968-985
DOI 10.1016/j.ccell.2016.10.006, PubMed 27866851
Loss of interleukin 33 expression in colonic crypts - a potential marker for disease remission in ulcerative colitis
Sci Rep, 6, 35403
DOI 10.1038/srep35403, PubMed 27748438
Single Nucleotide Polymorphisms and Long-Term Clinical Outcome in Renal Transplant Patients: A Validation Study
Am J Transplant, 17 (2), 528-533
DOI 10.1111/ajt.13995, PubMed 27483393
Adoptive Transfer of Tumor-Specific Th2 Cells Eradicates Tumors by Triggering an In Situ Inflammatory Immune Response
Cancer Res, 76 (23), 6864-6876
DOI 10.1158/0008-5472.CAN-16-1219, PubMed 27634753
The biliary epithelium presents antigens to and activates natural killer T cells
Hepatology, 62 (4), 1249-59
DOI 10.1002/hep.27840, PubMed 25855031
Oligomerized, filamentous surface presentation of RANTES/CCL5 on vascular endothelial cells
Sci Rep, 5, 9261
DOI 10.1038/srep09261, PubMed 25791723
Epidermal Expression and Regulation of Interleukin-33 during Homeostasis and Inflammation: Strong Species Differences
J Invest Dermatol, 135 (7), 1771-1780
DOI 10.1038/jid.2015.85, PubMed 25739051
Expression of the T cell-specific adapter protein in human tissues
Scand J Immunol, 80 (3), 169-79
DOI 10.1111/sji.12199, PubMed 24910151
Generation and characterization of an immortalized human mesenchymal stromal cell line
Stem Cells Dev, 23 (19), 2377-89
DOI 10.1089/scd.2013.0599, PubMed 24857590
Indirect CD4+ T-cell-mediated elimination of MHC II(NEG) tumor cells is spatially restricted and fails to prevent escape of antigen-negative cells
Eur J Immunol, 44 (9), 2625-37
DOI 10.1002/eji.201444659, PubMed 24846412
Interleukin-33 drives a proinflammatory endothelial activation that selectively targets nonquiescent cells
Arterioscler Thromb Vasc Biol, 33 (2), e47-55
DOI 10.1161/ATVBAHA.112.253427, PubMed 23162017
The alarmin IL-33 is a notch target in quiescent endothelial cells
Am J Pathol, 181 (3), 1099-111
DOI 10.1016/j.ajpath.2012.06.003, PubMed 22809957
Statins affect the presentation of endothelial chemokines by targeting to multivesicular bodies
PLoS One, 7 (7), e40673
DOI 10.1371/journal.pone.0040673, PubMed 22815786
Endostatin suppresses IGF-II-mediated signaling and invasion of human extravillous trophoblasts
Endocrinology, 152 (11), 4431-42
DOI 10.1210/en.2011-1196, PubMed 21933871
Inflammation driven by tumour-specific Th1 cells protects against B-cell cancer
Nat Commun, 2, 240
DOI 10.1038/ncomms1239, PubMed 21407206
Inflammatory bowel disease-associated interleukin-33 is preferentially expressed in ulceration-associated myofibroblasts
Am J Pathol, 177 (6), 2804-15
DOI 10.2353/ajpath.2010.100378, PubMed 21037074
Genome-wide transcription profile of endothelial cells after cardiac transplantation in the rat
Am J Transplant, 10 (7), 1534-44
DOI 10.1111/j.1600-6143.2010.03157.x, PubMed 20642680
The murine IL-8 homologues KC, MIP-2, and LIX are found in endothelial cytoplasmic granules but not in Weibel-Palade bodies
J Leukoc Biol, 87 (3), 501-8
DOI 10.1189/jlb.0809532, PubMed 20007247
Liprin (beta)1 is highly expressed in lymphatic vasculature and is important for lymphatic vessel integrity
Blood, 115 (4), 906-9
DOI 10.1182/blood-2009-03-212274, PubMed 19965622
Family-with-sequence-similarity-46, member A (Fam46a) gene is expressed in developing tooth buds
Arch Oral Biol, 54 (11), 1002-7
DOI 10.1016/j.archoralbio.2009.08.005, PubMed 19740458
Molecular requirements for sorting of the chemokine interleukin-8/CXCL8 to endothelial Weibel-Palade bodies
J Biol Chem, 284 (35), 23532-9
DOI 10.1074/jbc.M900874200, PubMed 19578117
Nuclear interleukin-33 is generally expressed in resting endothelium but rapidly lost upon angiogenic or proinflammatory activation
Am J Pathol, 173 (4), 1229-42
DOI 10.2353/ajpath.2008.080014, PubMed 18787100
Cytokine secretion depends on Galalpha(1,3)Gal expression in a pig-to-human whole blood model
J Immunol, 180 (9), 6346-53
DOI 10.4049/jimmunol.180.9.6346, PubMed 18424758
A potential role of the CXC chemokine GROalpha in atherosclerosis and plaque destabilization: downregulatory effects of statins
Arterioscler Thromb Vasc Biol, 28 (5), 1005-11
DOI 10.1161/ATVBAHA.108.162305, PubMed 18276907
The HUVEC/Matrigel assay: an in vivo assay of human angiogenesis suitable for drug validation
Methods Mol Biol, 360, 253-68
DOI 10.1385/1-59745-165-7:253, PubMed 17172733
Human complement-activating immunoglobulin (Ig)G3 antibodies are essential for porcine endothelial cell activation
Xenotransplantation, 13 (3), 215-23
DOI 10.1111/j.1399-3089.2006.00289.x, PubMed 16756564
Characterization of a novel chemokine-containing storage granule in endothelial cells: evidence for preferential exocytosis mediated by protein kinase A and diacylglycerol
J Immunol, 175 (8), 5358-69
DOI 10.4049/jimmunol.175.8.5358, PubMed 16210642
Low mannose-binding lectin and increased complement activation correlate to allograft vasculopathy, ischaemia, and rejection after human heart transplantation
Eur Heart J, 26 (16), 1660-5
DOI 10.1093/eurheartj/ehi198, PubMed 15821010
Disparate lymphoid chemokine expression in mice and men: no evidence of CCL21 synthesis by human high endothelial venules
Blood, 106 (2), 444-6
DOI 10.1182/blood-2004-11-4353, PubMed 15863780
A role for CCR4 in development of mature circulating cutaneous T helper memory cell populations
J Exp Med, 201 (7), 1045-51
DOI 10.1084/jem.20041059, PubMed 15795234
Primary antitumor immune response mediated by CD4+ T cells
Immunity, 22 (3), 371-83
DOI 10.1016/j.immuni.2005.02.003, PubMed 15780993
Tissue transglutaminase-mediated formation and cleavage of histamine-gliadin complexes: biological effects and implications for celiac disease
J Immunol, 174 (3), 1657-63
DOI 10.4049/jimmunol.174.3.1657, PubMed 15661929
Endostatin dramatically inhibits endothelial cell migration, vascular morphogenesis, and perivascular cell recruitment in vivo
Blood, 105 (3), 1044-51
DOI 10.1182/blood-2004-03-1164, PubMed 15466935
Monocyte-like and mature macrophages produce CXCL13 (B cell-attracting chemokine 1) in inflammatory lesions with lymphoid neogenesis
Blood, 104 (10), 3021-7
DOI 10.1182/blood-2004-02-0701, PubMed 15284119
Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments
Blood, 104 (2), 314-20
DOI 10.1182/blood-2003-08-2891, PubMed 15044249
Plasticity of endothelial cells: rapid dedifferentiation of freshly isolated high endothelial venule endothelial cells outside the lymphoid tissue microenvironment
Blood, 103 (11), 4164-72
DOI 10.1182/blood-2003-10-3537, PubMed 14976058
Endothelial cell diversity revealed by global expression profiling
Proc Natl Acad Sci U S A, 100 (19), 10623-8
DOI 10.1073/pnas.1434429100, PubMed 12963823
Molecular characterization of NF-HEV, a nuclear factor preferentially expressed in human high endothelial venules
Am J Pathol, 163 (1), 69-79
DOI 10.1016/S0002-9440(10)63631-0, PubMed 12819012
Human serum-induced porcine endothelial cell E-selectin expression is associated with IgG3 and IgM anti-Gal antibodies
Xenotransplantation, 9 (5), 350-8
DOI 10.1034/j.1399-3089.2002.01094.x, PubMed 12199866
B cell attracting chemokine 1 (CXCL13) and its receptor CXCR5 are expressed in normal and aberrant gut associated lymphoid tissue
Gut, 51 (3), 364-71
DOI 10.1136/gut.51.3.364, PubMed 12171958
CD38 is a marker of human lacteals
Virchows Arch, 441 (6), 605-13
DOI 10.1007/s00428-002-0679-9, PubMed 12461619
Vascular morphogenesis and differentiation after adoptive transfer of human endothelial cells to immunodeficient mice
Am J Pathol, 160 (5), 1629-37
DOI 10.1016/S0002-9440(10)61110-8, PubMed 12000715
Human serum-induced expression of E-selectin on porcine aortic endothelial cells in vitro is totally complement mediated
Transplantation, 72 (12), 1967-73
DOI 10.1097/00007890-200112270-00017, PubMed 11773897
The CCR7 ligand elc (CCL19) is transcytosed in high endothelial venules and mediates T cell recruitment
J Exp Med, 193 (9), 1105-12
DOI 10.1084/jem.193.9.1105, PubMed 11342595
C1-inhibitor attenuates human serum induced E-selectin expression of pig aortic endothelial cells
Transplant Proc, 33 (1-2), 789-90
DOI 10.1016/s0041-1345(00)02256-9, PubMed 11267073
Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: Epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity
J Exp Med, 192 (5), 761-8
DOI 10.1084/jem.192.5.761, PubMed 10974041
Human intestinal endothelium shows high susceptibility to cytomegalovirus and altered expression of adhesion molecules after infection
Scand J Immunol, 51 (4), 354-60
DOI 10.1046/j.1365-3083.2000.00676.x, PubMed 10736107
Heterogeneity of endothelial cells: the specialized phenotype of human high endothelial venules characterized by suppression subtractive hybridization
Am J Pathol, 155 (6), 2043-55
DOI 10.1016/S0002-9440(10)65523-X, PubMed 10595934
The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells
Nature, 400 (6746), 776-80
DOI 10.1038/23495, PubMed 10466728
New insights into the immunopathology of human inflammatory bowel disease
Drugs Today, 35 A, 33-70
Culture characterization of differentiated high endothelial venule cells from human tonsils
Lab Invest, 79 (3), 327-36
PubMed 10092069
Microvascular endothelial cells and leukocyte emigration
FALK SYMP, 110, 383-400
Rapid secretion of prestored interleukin 8 from Weibel-Palade bodies of microvascular endothelial cells
J Exp Med, 188 (9), 1751-6
DOI 10.1084/jem.188.9.1751, PubMed 9802986
Cytokine profiles of cultured microvascular endothelial cells from the human intestine
Gut, 42 (5), 635-42
DOI 10.1136/gut.42.5.635, PubMed 9659156
Major histocompatibility complex class II-dependent antigen presentation by human intestinal endothelial cells
Gastroenterology, 114 (4), 649-56
DOI 10.1016/s0016-5085(98)70578-5, PubMed 9516385
Cellular and molecular mechanisms for induction of mucosal immunity
Dev. Biols, 92, 93-108
Mucosal immunology of the upper airways: an overview
Ann N Y Acad Sci, 830, 1-18
DOI 10.1111/j.1749-6632.1997.tb51875.x, PubMed 9616663
Mechanism for enhanced external transfer of dimeric IgA over pentameric IgM: studies of diffusion, binding to the human polymeric Ig receptor, and epithelial transcytosis
J Immunol, 159 (9), 4330-40
PubMed 9379029
Expression of functional VCAM-1 by cultured nasal polyp-derived microvascular endothelium
Am J Pathol, 150 (6), 2113-23
PubMed 9176402
Immunopathological mechanisms in inflammatory bowel disease
FALK SYMP, 91, 15-51
Cytokine-regulated expression of E-selectin, intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1) in human microvascular endothelial cells
J Immunol, 156 (7), 2558-65
PubMed 8786319
Respiratory burst of intestinal macrophages in inflammatory bowel disease is mainly caused by CD14+L1+ monocyte derived cells
Gut, 37 (3), 367-73
DOI 10.1136/gut.37.3.367, PubMed 7590432
Isolation and longterm culture of human intestinal microvascular endothelial cells
Gut, 37 (2), 225-34
DOI 10.1136/gut.37.2.225, PubMed 7557573
Eosinophil infiltration is related to increased expression of vascular cell adhesion molecule-1 in nasal polyps
Am J Respir Cell Mol Biol, 12 (6), 624-32
DOI 10.1165/ajrcmb.12.6.7539273, PubMed 7539273
Differential interference contrast microscopy combined with immunofluorescence: a new method to phenotype eosinophils in situ
J Immunol Methods, 173 (1), 77-91
DOI 10.1016/0022-1759(94)90285-2, PubMed 8034989
Review articles
Targeting the Notch Signaling Pathway in Chronic Inflammatory Diseases
Front Immunol, 12, 668207
DOI 10.3389/fimmu.2021.668207, PubMed 33912195
Endothelial Cells in Emerging Viral Infections
Front Cardiovasc Med, 8, 619690
DOI 10.3389/fcvm.2021.619690, PubMed 33718448
Tenascins in fibrotic disorders-from bench to bedside
Cell Adh Migr, 9 (1-2), 83-9
DOI 10.4161/19336918.2014.994901, PubMed 25793575
Interleukin-33 - cytokine of dual function or novel alarmin?
Trends Immunol, 30 (5), 227-33
DOI 10.1016/j.it.2009.03.003, PubMed 19359217
Cellular and molecular mechanisms for induction of mucosal immunity
Dev Biol Stand, 92, 93-108
PubMed 9554262
Mucosal immunity--a major adaptive defence mechanism
Behring Inst Mitt (98), 1-23
PubMed 9382729
Immunopathology of human inflammatory bowel disease
Springer Semin Immunopathol, 18 (4), 555-89
DOI 10.1007/BF00824058, PubMed 9144870
Other articles
Obituary - In Memoriam Per Brandtzaeg
Scand J Immunol, 84 (6), 370-372
DOI 10.1111/sji.12505, PubMed 28025869
Coy decoy with a new ploy: interceptor controls the levels of homeostatic chemokines
Eur J Immunol, 36 (7), 1659-61
DOI 10.1002/eji.200636327, PubMed 16791884
Regional specialization in the mucosal immune system: primed cells do not always home along the same track
Immunol Today, 20 (6), 267-77
DOI 10.1016/s0167-5699(99)01468-1, PubMed 10354552
Immunopathology of human inflammatory bowel disease (vol 18, pg 555, 1997)
Springer Semin. Immunopathol., 19 (2), 269
DOI 10.1007/BF00870274
Immunofluorescent evidence for presence of interleukin-1 in normal and diseased human skeletal muscle
Muscle Nerve, 11 (8), 890-2
DOI 10.1002/mus.880110814, PubMed 3050511
Theses
Functional studies of cultured human gut endothelium: characterization of biological properties with special reference to inflammatory bowel disease
Laboratory for Immunohistochemistry and Immunopathology, Institute of Pathology, Department Group for Laboratory Medicine, Faculty of Medicine, Rikshospitalet, University of Oslo, Oslo, 1 b. (flere pag.)
BIBSYS 970155921, ISBN 82-7633-085-1