Publications by Frode Lars Jahnsen
112 publications found
Original articles
The prognostic effect of tumor-associated macrophages in stage I-III colorectal cancer depends on T cell infiltration
Cell Oncol (Dordr) (in press)
DOI 10.1007/s13402-024-00926-w, PubMed 38407700
Allogeneic bone marrow transplantation for patients with treatment-refractory Crohn's Disease
Heliyon, 10 (1), e24026
DOI 10.1016/j.heliyon.2024.e24026, PubMed 38283244
Separate Gut Plasma Cell Populations Produce Auto-Antibodies against Transglutaminase 2 and Transglutaminase 3 in Dermatitis Herpetiformis
Adv Sci (Weinh), 10 (25), e2300401
DOI 10.1002/advs.202300401, PubMed 37424036
Human small intestine contains 2 functionally distinct regulatory T-cell subsets
J Allergy Clin Immunol, 152 (1), 278-289.e6
DOI 10.1016/j.jaci.2023.02.030, PubMed 36893861
Cellsnake: a user-friendly tool for single-cell RNA sequencing analysis
Gigascience, 12
DOI 10.1093/gigascience/giad091, PubMed 37889009
Single cell transcriptomic analysis of the immune cell compartment in the human small intestine and in Celiac disease
Nat Commun, 13 (1), 4920
DOI 10.1038/s41467-022-32691-5, PubMed 35995787
Single-cell transcriptomic analysis of human colonic macrophages reveals niche-specific subsets
J Exp Med, 219 (3)
DOI 10.1084/jem.20211846, PubMed 35139155
Calprotectin Expressing Donor-Derived Macrophages Increase in Acute Gastrointestinal Graft-Versus-Host Disease
Transplant Cell Ther, 28 (5), 248.e1-248.e8
DOI 10.1016/j.jtct.2022.01.028, PubMed 35144036
Peripheral host T cells survive hematopoietic stem cell transplantation and promote graft-versus-host disease
J Clin Invest, 130 (9), 4624-4636
DOI 10.1172/JCI129965, PubMed 32516138
CD4+ T cells persist for years in the human small intestine and display a TH1 cytokine profile
Mucosal Immunol, 14 (2), 402-410
DOI 10.1038/s41385-020-0315-5, PubMed 32572129
Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced
J Pathol Clin Res, 5 (4), 248-255
DOI 10.1002/cjp2.140, PubMed 31493350
Resident memory CD8 T cells persist for years in human small intestine
J Exp Med, 216 (10), 2412-2426
DOI 10.1084/jem.20190414, PubMed 31337737
Plasma Cells Are the Most Abundant Gluten Peptide MHC-expressing Cells in Inflamed Intestinal Tissues From Patients With Celiac Disease
Gastroenterology, 156 (5), 1428-1439.e10
DOI 10.1053/j.gastro.2018.12.013, PubMed 30593798
Monocytes accumulate in the airways of children with fatal asthma
Clin Exp Allergy, 48 (12), 1631-1639
DOI 10.1111/cea.13265, PubMed 30184280
Transcriptional profiling reveals monocyte-related macrophages phenotypically resembling DC in human intestine
Mucosal Immunol, 11 (5), 1512-1523
DOI 10.1038/s41385-018-0060-1, PubMed 30038215
Oral exposure to the free amino acid glycine inhibits the acute allergic response in a model of cow's milk allergy in mice
Nutr Res, 58, 95-105
DOI 10.1016/j.nutres.2018.07.005, PubMed 30340819
Transcriptional and functional profiling defines human small intestinal macrophage subsets
J Exp Med, 215 (2), 441-458
DOI 10.1084/jem.20170057, PubMed 29273642
Immunohistology and remodeling in fatal pediatric and adolescent asthma
Respir Res, 18 (1), 94
DOI 10.1186/s12931-017-0575-0, PubMed 28511697
Antibody-secreting plasma cells persist for decades in human intestine
J Exp Med, 214 (2), 309-317
DOI 10.1084/jem.20161590, PubMed 28104812
Long-term persistence of human donor alveolar macrophages in lung transplant recipients
Thorax, 71 (11), 1006-1011
DOI 10.1136/thoraxjnl-2016-208292, PubMed 27329043
CD1c-Expression by Monocytes - Implications for the Use of Commercial CD1c+ Dendritic Cell Isolation Kits
PLoS One, 11 (6), e0157387
DOI 10.1371/journal.pone.0157387, PubMed 27311059
Characterization of Regulatory T-Cell Markers in CD4+ T Cells of the Upper Airway Mucosa
PLoS One, 11 (2), e0148826
DOI 10.1371/journal.pone.0148826, PubMed 26866695
Rapid recruitment of CD14(+) monocytes in experimentally induced allergic rhinitis in human subjects
J Allergy Clin Immunol, 137 (6), 1872-1881.e12
DOI 10.1016/j.jaci.2015.11.025, PubMed 26851967
Ichthyosis prematurity syndrome caused by a novel missense mutation in FATP4 gene-a case report from India
Clin Case Rep, 4 (1), 87-9
DOI 10.1002/ccr3.462, PubMed 26783444
Insulitis and characterisation of infiltrating T cells in surgical pancreatic tail resections from patients at onset of type 1 diabetes
Diabetologia, 59 (3), 492-501
DOI 10.1007/s00125-015-3820-4, PubMed 26602422
IL-5 production by resident mucosal allergen-specific T cells in an explant model of allergic rhinitis
Clin Exp Allergy, 45 (8), 1296-304
DOI 10.1111/cea.12543, PubMed 25817862
Lung function, airway remodeling, and inflammation in infants: outcome at 8 years
Ann Allergy Asthma Immunol, 114 (2), 90-6
DOI 10.1016/j.anai.2014.09.019, PubMed 25455519
The frequencies of IFNγ+IL2+TNFα+ PPD-specific CD4+CD45RO+ T-cells correlate with the magnitude of the QuantiFERON® gold in-tube response in a prospective study of healthy indian adolescents
PLoS One, 9 (7), e101224
DOI 10.1371/journal.pone.0101224, PubMed 24992314
A thymic stromal lymphopoietin-responsive dendritic cell subset mediates allergic responses in the upper airway mucosa
J Allergy Clin Immunol, 134 (3), 613-621.e7
DOI 10.1016/j.jaci.2014.05.010, PubMed 24958565
A role for CCL28-CCR3 in T-cell homing to the human upper airway mucosa
Mucosal Immunol, 8 (1), 107-14
DOI 10.1038/mi.2014.46, PubMed 24917456
The short form of TSLP is constitutively translated in human keratinocytes and has characteristics of an antimicrobial peptide
Mucosal Immunol, 8 (1), 49-56
DOI 10.1038/mi.2014.41, PubMed 24850429
Immunological changes and increased expression of myxovirus resistance protein a in thyroid tissue of patients with recent onset and untreated Graves' disease
Thyroid, 24 (3), 537-44
DOI 10.1089/thy.2013.0287, PubMed 24032645
Mucosal cytokine response after short-term gluten challenge in celiac disease and non-celiac gluten sensitivity
Am J Gastroenterol, 108 (5), 842-50
DOI 10.1038/ajg.2013.91, PubMed 23588237
Plasmacytoid dendritic cells are scarcely represented in the human gut mucosa and are not recruited to the celiac lesion
Mucosal Immunol, 6 (5), 985-92
DOI 10.1038/mi.2012.136, PubMed 23340820
Inflammation and increased myxovirus resistance protein A expression in thyroid tissue in the early stages of Hashimoto's thyroiditis
Thyroid, 23 (3), 334-41
DOI 10.1089/thy.2012.0264, PubMed 22998463
Serum response factor controls transcriptional network regulating epidermal function and hair follicle morphogenesis
J Invest Dermatol, 133 (3), 608-617
DOI 10.1038/jid.2012.378, PubMed 23151848
Research needs in allergy: an EAACI position paper, in collaboration with EFA
Clin Transl Allergy, 2 (1), 21
DOI 10.1186/2045-7022-2-21, PubMed 23121771
Epithelial-microbial crosstalk in polymeric Ig receptor deficient mice
Eur J Immunol, 42 (11), 2959-70
DOI 10.1002/eji.201242543, PubMed 22865203
Prenatal sonographic assessment and perinatal course of ichthyosis prematurity syndrome
Ultrasound Obstet Gynecol, 39 (4), 473-7
DOI 10.1002/uog.9014, PubMed 21465607
Rapid accumulation of CD14+CD11c+ dendritic cells in gut mucosa of celiac disease after in vivo gluten challenge
PLoS One, 7 (3), e33556
DOI 10.1371/journal.pone.0033556, PubMed 22438948
Sun exposure rapidly reduces plasmacytoid dendritic cells and inflammatory dermal dendritic cells in psoriatic skin
Br J Dermatol, 165 (4), 792-801
DOI 10.1111/j.1365-2133.2011.10430.x, PubMed 21623747
Ichthyosis prematurity syndrome: clinical evaluation of 17 families with a rare disorder of lipid metabolism
J Am Acad Dermatol, 66 (4), 606-16
DOI 10.1016/j.jaad.2011.04.014, PubMed 21856041
Density of CD163+ CD11c+ dendritic cells increases and CD103+ dendritic cells decreases in the coeliac lesion
Scand J Immunol, 74 (2), 186-94
DOI 10.1111/j.1365-3083.2011.02549.x, PubMed 21392045
Depletion of murine intestinal microbiota: effects on gut mucosa and epithelial gene expression
PLoS One, 6 (3), e17996
DOI 10.1371/journal.pone.0017996, PubMed 21445311
Experimentally induced accumulation of Foxp3⁺ T cells in upper airway allergy
Clin Exp Allergy, 41 (7), 954-62
DOI 10.1111/j.1365-2222.2011.03710.x, PubMed 21418344
Assessing possible celiac disease by an HLA-DQ2-gliadin Tetramer Test
Am J Gastroenterol, 106 (7), 1318-24
DOI 10.1038/ajg.2011.23, PubMed 21364548
Sun exposure induces rapid immunological changes in skin and peripheral blood in patients with psoriasis
Br J Dermatol, 164 (2), 344-55
DOI 10.1111/j.1365-2133.2010.10149.x, PubMed 21271993
Characterisation of bronchus-associated lymphoid tissue and antigen-presenting cells in central airway mucosa of children
Thorax, 66 (2), 151-6
DOI 10.1136/thx.2010.149591, PubMed 21163807
Depletion of CD4+CD25+CD127lo regulatory T cells does not increase allergen-driven T cell activation
Clin Exp Allergy, 38 (11), 1752-9
DOI 10.1111/j.1365-2222.2008.03081.x, PubMed 18681851
Depletion of CD4+ CD25+ regulatory T cells inhibits local tumour growth in a mouse model of B cell lymphoma
Clin Exp Immunol, 152 (2), 381-7
DOI 10.1111/j.1365-2249.2008.03642.x, PubMed 18341610
Bronchial response pattern of antigen presenting cells and regulatory T cells in children less than 2 years of age
Thorax, 63 (8), 703-9
DOI 10.1136/thx.2007.082974, PubMed 18250182
Regulatory T cells in colorectal cancer patients suppress anti-tumor immune activity in a COX-2 dependent manner
Cancer Immunol Immunother, 57 (6), 813-21
DOI 10.1007/s00262-007-0417-x, PubMed 17962941
Surface expression of transglutaminase 2 by dendritic cells and its potential role for uptake and presentation of gluten peptides to T cells
Scand J Immunol, 65 (3), 213-20
DOI 10.1111/j.1365-3083.2006.01881.x, PubMed 17309775
Plasmacytoid DCs regulate recall responses by rapid induction of IL-10 in memory T cells
Blood, 109 (8), 3369-76
DOI 10.1182/blood-2006-06-031484, PubMed 17158235
Accelerated antigen sampling and transport by airway mucosal dendritic cells following inhalation of a bacterial stimulus
J Immunol, 177 (9), 5861-7
DOI 10.4049/jimmunol.177.9.5861, PubMed 17056510
Plasmacytoid dendritic cells induce a distinct cytokine pattern in virus-specific CD4+ memory T cells that is modulated by CpG oligodeoxynucleotides
Scand J Immunol, 64 (4), 404-11
DOI 10.1111/j.1365-3083.2006.01792.x, PubMed 16970682
A unique dendritic cell subset accumulates in the celiac lesion and efficiently activates gluten-reactive T cells
Gastroenterology, 131 (2), 428-38
DOI 10.1053/j.gastro.2006.06.002, PubMed 16890596
Human dendritic cell expression of HLA-DO is subset specific and regulated by maturation
J Immunol, 176 (6), 3536-47
DOI 10.4049/jimmunol.176.6.3536, PubMed 16517722
CD11c+ dendritic cells and plasmacytoid DCs are activated by human cytomegalovirus and retain efficient T cell-stimulatory capability upon infection
Blood, 107 (5), 2022-9
DOI 10.1182/blood-2005-05-2016, PubMed 16269620
Differential capability for phagocytosis of apoptotic and necrotic leukemia cells by human peripheral blood dendritic cell subsets
J Leukoc Biol, 77 (5), 689-98
DOI 10.1189/jlb.1204711, PubMed 15728242
Cerebral thrombotic microangiopathy and antiphospholipid antibodies in Aicardi-Goutieres syndrome--report of two sisters
Neuropediatrics, 36 (1), 40-4
DOI 10.1055/s-2004-830532, PubMed 15776321
The CMRF58 antibody recognizes a subset of CD123hi dendritic cells in allergen-challenged mucosa
J Leukoc Biol, 77 (3), 344-51
DOI 10.1189/jlb.1004559, PubMed 15569693
Plasmacytoid dendritic cells activate allergen-specific TH2 memory cells: modulation by CpG oligodeoxynucleotides
J Allergy Clin Immunol, 114 (2), 436-43
DOI 10.1016/j.jaci.2004.04.035, PubMed 15316529
[Pulmonary veno-occlusive disease in a patient with scleroderma and the CREST syndrome]
Tidsskr Nor Laegeforen, 123 (23), 3391-2
PubMed 14713977
Endothelial cell diversity revealed by global expression profiling
Proc Natl Acad Sci U S A, 100 (19), 10623-8
DOI 10.1073/pnas.1434429100, PubMed 12963823
Molecular characterization of NF-HEV, a nuclear factor preferentially expressed in human high endothelial venules
Am J Pathol, 163 (1), 69-79
DOI 10.1016/S0002-9440(10)63631-0, PubMed 12819012
Bidirectional interactions between antigen-bearing respiratory tract dendritic cells (DCs) and T cells precede the late phase reaction in experimental asthma: DC activation occurs in the airway mucosa but not in the lung parenchyma
J Exp Med, 198 (1), 19-30
DOI 10.1084/jem.20021328, PubMed 12835476
Human nasal mucosa contains antigen-presenting cells of strikingly different functional phenotypes
Am J Respir Cell Mol Biol, 30 (1), 31-7
DOI 10.1165/rcmb.2002-0230OC, PubMed 12829449
Involvement of plasmacytoid dendritic cells in human diseases
Hum Immunol, 63 (12), 1201-5
DOI 10.1016/s0198-8859(02)00759-0, PubMed 12480264
A site-specific plectin mutation causes dominant epidermolysis bullosa simplex Ogna: two identical de novo mutations
J Invest Dermatol, 118 (1), 87-93
DOI 10.1046/j.0022-202x.2001.01591.x, PubMed 11851880
Rapid dendritic cell recruitment to the bronchial mucosa of patients with atopic asthma in response to local allergen challenge
Thorax, 56 (11), 823-6
DOI 10.1136/thorax.56.11.823, PubMed 11641504
Plasmacytoid dendritic cells (natural interferon- alpha/beta-producing cells) accumulate in cutaneous lupus erythematosus lesions
Am J Pathol, 159 (1), 237-43
DOI 10.1016/s0002-9440(10)61689-6, PubMed 11438470
Experimentally induced recruitment of plasmacytoid (CD123high) dendritic cells in human nasal allergy
J Immunol, 165 (7), 4062-8
DOI 10.4049/jimmunol.165.7.4062, PubMed 11034417
Immunohistochemistry in research and diagnosis of celiac disease
Methods Mol Med, 41, 203-39
DOI 10.1385/1-59259-082-9:203, PubMed 21374442
Glucocorticosteroids inhibit mRNA expression for eotaxin, eotaxin-2, and monocyte-chemotactic protein-4 in human airway inflammation with eosinophilia
J Immunol, 163 (3), 1545-51
PubMed 10415058
Culture characterization of differentiated high endothelial venule cells from human tonsils
Lab Invest, 79 (3), 327-36
PubMed 10092069
Antigen presentation and stimulation of the immune system in human airways
Allergy, 54 Suppl 57, 37-49
DOI 10.1111/j.1398-9995.1999.tb04405.x, PubMed 10565479
Rapid secretion of prestored interleukin 8 from Weibel-Palade bodies of microvascular endothelial cells
J Exp Med, 188 (9), 1751-6
DOI 10.1084/jem.188.9.1751, PubMed 9802986
Gluten induces an intestinal cytokine response strongly dominated by interferon gamma in patients with celiac disease
Gastroenterology, 115 (3), 551-63
DOI 10.1016/s0016-5085(98)70134-9, PubMed 9721152
Cytokine profiles of cultured microvascular endothelial cells from the human intestine
Gut, 42 (5), 635-42
DOI 10.1136/gut.42.5.635, PubMed 9659156
Phenotypic distribution of T cells in human nasal mucosa differs from that in the gut
Am J Respir Cell Mol Biol, 18 (3), 392-401
DOI 10.1165/ajrcmb.18.3.2995, PubMed 9490657
Mucosal immunology of the upper airways: an overview
Ann N Y Acad Sci, 830, 1-18
DOI 10.1111/j.1749-6632.1997.tb51875.x, PubMed 9616663
Expression of functional VCAM-1 by cultured nasal polyp-derived microvascular endothelium
Am J Pathol, 150 (6), 2113-23
PubMed 9176402
Plectin abnormality in epidermolysis bullosa simplex Ogna: non-responsiveness of basal keratinocytes to some anti-rat plectin antibodies
Exp Dermatol, 6 (1), 41-8
DOI 10.1111/j.1600-0625.1997.tb00144.x, PubMed 9067706
Eosinophil infiltration is related to increased expression of vascular cell adhesion molecule-1 in nasal polyps
Am J Respir Cell Mol Biol, 12 (6), 624-32
DOI 10.1165/ajrcmb.12.6.7539273, PubMed 7539273
Immunostaining with monoclonal antibodies to eosinophil cationic protein (EG1 and EG2) does not distinguish between resting and activated eosinophils in formalin-fixed tissue specimens
Adv Exp Med Biol, 371A, 283-6
DOI 10.1007/978-1-4615-1941-6_59, PubMed 8525926
Monoclonal antibody EG2 does not provide reliable immunohistochemical discrimination between resting and activated eosinophils
J Immunol Methods, 175 (1), 23-36
DOI 10.1016/0022-1759(94)90328-x, PubMed 7930638
Differential interference contrast microscopy combined with immunofluorescence: a new method to phenotype eosinophils in situ
J Immunol Methods, 173 (1), 77-91
DOI 10.1016/0022-1759(94)90285-2, PubMed 8034989
Distribution of macrophages and granulocytes expressing L1 protein (calprotectin) in human Peyer's patches compared with normal ileal lamina propria and mesenteric lymph nodes
Gut, 34 (10), 1357-63
DOI 10.1136/gut.34.10.1357, PubMed 8244101
Review articles
A Roadmap for the Human Gut Cell Atlas
Nat Rev Gastroenterol Hepatol, 20 (9), 597-614
DOI 10.1038/s41575-023-00784-1, PubMed 37258747
Do Long-Lived Plasma Cells Maintain a Healthy Microbiota in the Gut?
Trends Immunol, 39 (3), 196-208
DOI 10.1016/j.it.2017.10.006, PubMed 29162322
Role of fatty acid transporters in epidermis: Implications for health and disease
Dermatoendocrinol, 3 (2), 53-61
DOI 10.4161/derm.3.2.14816, PubMed 21695012
Pathogenic mechanisms of allergic inflammation: atopic asthma as a paradigm
Adv Immunol, 104, 51-113
DOI 10.1016/S0065-2776(08)04003-0, PubMed 20457116
Regulation of immunological homeostasis in the respiratory tract
Nat Rev Immunol, 8 (2), 142-52
DOI 10.1038/nri2236, PubMed 18204469
Regional specialization in the mucosal immune system: what happens in the microcompartments?
Immunol Today, 20 (3), 141-51
DOI 10.1016/s0167-5699(98)01413-3, PubMed 10203706
Cellular and molecular mechanisms for induction of mucosal immunity
Dev Biol Stand, 92, 93-108
PubMed 9554262
Mucosal immunity--a major adaptive defence mechanism
Behring Inst Mitt (98), 1-23
PubMed 9382729
Immune functions and immunopathology of the mucosa of the upper respiratory pathways
Acta Otolaryngol, 116 (2), 149-59
DOI 10.3109/00016489609137812, PubMed 8725503
Other articles
Correction to: Separate Gut Plasma Cell Populations Produce Auto-Antibodies against Transglutaminase 2 and Transglutaminase 3 in Dermatitis Herpetiformis
Adv Sci (Weinh), e2400894 (in press)
DOI 10.1002/advs.202400894, PubMed 38477397
Response to Lauro and Zorzetti
Mucosal Immunol, 14 (6), 1395-1396
DOI 10.1038/s41385-021-00454-y, PubMed 34535772
Legends of allergology and immunology: Per Brandtzaeg - Pillar of mucosal immunology
Allergy, 76 (8), 2634-2635
DOI 10.1111/all.14824, PubMed 33752264
Lung CD4+ T-cells in patients with lung fibrosis produce pro-fibrotic interleukin-13 together with interferon-γ
Eur Respir J, 57 (3)
DOI 10.1183/13993003.00983-2020, PubMed 33154027
Obituary - In Memoriam Per Brandtzaeg
Scand J Immunol, 84 (6), 370-372
DOI 10.1111/sji.12505, PubMed 28025869
Ichthyosis prematurity syndrome caused by a novel fatty acid transport protein 4 gene mutation in a German infant
Arch Dermatol, 147 (6), 750-2
DOI 10.1001/archdermatol.2011.139, PubMed 21690550
Eosinophils and T cells in fatal asthma
Am J Respir Crit Care Med, 155 (3), 1167-8
DOI 10.1164/ajrccm.155.3.9117005, PubMed 9117005
Monoclonal antibody EG2 reactivity cannot be used as an immunohistochemical activation marker for eosinophils
J Leukoc Biol, 57 (3), 513-4
DOI 10.1002/jlb.57.3.513, PubMed 7884325
Erroneous immunohistochemical application of monoclonal antibody EG2 to detect cellular activation
Lancet, 344 (8935), 1514-5
DOI 10.1016/s0140-6736(94)90336-0, PubMed 7968154
Books
Hjerteinfarkt: diagnostikk og behandling
In Hjerteforum, Supplement, Norsk cardiologisk selskap, Oslo, 20(2007)nr. 1 (6. utg.), 72 s.
BIBSYS 070870217
Hjerteinfarkt: diagnostikk og behandling
In Hjerteforum, Supplement, Norsk cardiologisk selskap, Oslo, 2, 1999 (4. utg.), 80 s.
BIBSYS 990841952
Hjerteinfarkt: diagnostikk og behandling
In Hjerteforum, Supplement, Norsk cardiologisk selskap, Oslo, 2 - 1997, 55 s.
BIBSYS 97054328x
Diagnostikk og behandling av hjerteinfarkt og hjertestans
Norske Hoechst, Oslo (2. utg.), 34 s.
BIBSYS 931608015
Theses
Human mucosal eosinophils: identification and regulatory mechanisms of extravasationin the upper airways
Laboratory for Immunohistochemistry and Immunopathology, Institute of Pathology, Department Group for Laboratory Medicine, The National Hospital, Rikshospitalet, University of Oslo, Oslo, 1 b. (flere pag.)
BIBSYS 970627319, ISBN 82-7633-087-8