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Publications by Elin Bergseng

27 publications found

Original articles

Høydahl LS, Richter L, Frick R, Snir O, Gunnarsen KS, Landsverk OJB, Iversen R, Jeliazkov JR, Gray JJ, Bergseng E, Foss S, Qiao SW, Lundin KEA, Jahnsen J, Jahnsen FL, Sandlie I, Sollid LM, Løset GÅ (2018)
Plasma Cells Are the Most Abundant Gluten Peptide MHC-expressing Cells in Inflamed Intestinal Tissues From Patients With Celiac Disease
Gastroenterology, 156 (5), 1428-1439.e10
DOI 10.1053/j.gastro.2018.12.013, PubMed 30593798

Gunnarsen KS, Høydahl LS, Risnes LF, Dahal-Koirala S, Neumann RS, Bergseng E, Frigstad T, Frick R, du Pré MF, Dalhus B, Lundin KE, Qiao SW, Sollid LM, Sandlie I, Løset GÅ (2017)
A TCRα framework-centered codon shapes a biased T cell repertoire through direct MHC and CDR3β interactions
JCI Insight, 2 (17)
DOI 10.1172/jci.insight.95193, PubMed 28878121

Nguyen TB, Jayaraman P, Bergseng E, Madhusudhan MS, Kim CY, Sollid LM (2017)
Unraveling the structural basis for the unusually rich association of human leukocyte antigen DQ2.5 with class-II-associated invariant chain peptides
J Biol Chem, 292 (22), 9218-9228
DOI 10.1074/jbc.M117.785139, PubMed 28364043

Dørum S, Steinsbø Ø, Bergseng E, Arntzen MØ, de Souza GA, Sollid LM (2016)
Gluten-specific antibodies of celiac disease gut plasma cells recognize long proteolytic fragments that typically harbor T-cell epitopes
Sci Rep, 6, 25565
DOI 10.1038/srep25565, PubMed 27146306

Christophersen A, Risnes LF, Bergseng E, Lundin KE, Sollid LM, Qiao SW (2016)
Healthy HLA-DQ2.5+ Subjects Lack Regulatory and Memory T Cells Specific for Immunodominant Gluten Epitopes of Celiac Disease
J Immunol, 196 (6), 2819-26
DOI 10.4049/jimmunol.1501152, PubMed 26895834

Sollid LM, Iversen R, Steinsbø Ø, Qiao SW, Bergseng E, Dørum S, du Pré MF, Stamnaes J, Christophersen A, Cardoso I, Hnida K, Chen X, Snir O, Lundin KEA (2015)
Small bowel, celiac disease and adaptive immunity
Dig Dis, 33 (2), 115-121
DOI 10.1159/000369512, PubMed 25925911

Bergseng E, Dørum S, Arntzen MØ, Nielsen M, Nygård S, Buus S, de Souza GA, Sollid LM (2014)
Different binding motifs of the celiac disease-associated HLA molecules DQ2.5, DQ2.2, and DQ7.5 revealed by relative quantitative proteomics of endogenous peptide repertoires
Immunogenetics, 67 (2), 73-84
DOI 10.1007/s00251-014-0819-9, PubMed 25502872

Dørum S, Bodd M, Fallang LE, Bergseng E, Christophersen A, Johannesen MK, Qiao SW, Stamnaes J, de Souza GA, Sollid LM (2014)
HLA-DQ molecules as affinity matrix for identification of gluten T cell epitopes
J Immunol, 193 (9), 4497-506
DOI 10.4049/jimmunol.1301466, PubMed 25261484

Christophersen A, Ráki M, Bergseng E, Lundin KE, Jahnsen J, Sollid LM, Qiao SW (2014)
Tetramer-visualized gluten-specific CD4+ T cells in blood as a potential diagnostic marker for coeliac disease without oral gluten challenge
United European Gastroenterol J, 2 (4), 268-78
DOI 10.1177/2050640614540154, PubMed 25083284

Bodd M, Ráki M, Bergseng E, Jahnsen J, Lundin KE, Sollid LM (2013)
Direct cloning and tetramer staining to measure the frequency of intestinal gluten-reactive T cells in celiac disease
Eur J Immunol, 43 (10), 2605-12
DOI 10.1002/eji.201343382, PubMed 23775608

Bodd M, Tollefsen S, Bergseng E, Lundin KE, Sollid LM (2012)
Evidence that HLA-DQ9 confers risk to celiac disease by presence of DQ9-restricted gluten-specific T cells
Hum Immunol, 73 (4), 376-81
DOI 10.1016/j.humimm.2012.01.016, PubMed 22342873

Brottveit M, Ráki M, Bergseng E, Fallang LE, Simonsen B, Løvik A, Larsen S, Løberg EM, Jahnsen FL, Sollid LM, Lundin KE (2011)
Assessing possible celiac disease by an HLA-DQ2-gliadin Tetramer Test
Am J Gastroenterol, 106 (7), 1318-24
DOI 10.1038/ajg.2011.23, PubMed 21364548

Bodd M, Ráki M, Tollefsen S, Fallang LE, Bergseng E, Lundin KE, Sollid LM (2010)
HLA-DQ2-restricted gluten-reactive T cells produce IL-21 but not IL-17 or IL-22
Mucosal Immunol, 3 (6), 594-601
DOI 10.1038/mi.2010.36, PubMed 20571486

Fallang LE, Bergseng E, Hotta K, Berg-Larsen A, Kim CY, Sollid LM (2009)
Differences in the risk of celiac disease associated with HLA-DQ2.5 or HLA-DQ2.2 are related to sustained gluten antigen presentation
Nat Immunol, 10 (10), 1096-101
DOI 10.1038/ni.1780, PubMed 19718029

Bethune MT, Crespo-Bosque M, Bergseng E, Mazumdar K, Doyle L, Sestak K, Sollid LM, Khosla C (2009)
Noninflammatory gluten peptide analogs as biomarkers for celiac sprue
Chem Biol, 16 (8), 868-81
DOI 10.1016/j.chembiol.2009.07.009, PubMed 19716477

Jüse U, Fleckenstein B, Bergseng E, Sollid LM (2008)
Soluble HLA-DQ2 expressed in S2 cells copurifies with a high affinity insect cell derived protein
Immunogenetics, 61 (2), 81-9
DOI 10.1007/s00251-008-0338-7, PubMed 18987854

Fallang LE, Roh S, Holm A, Bergseng E, Yoon T, Fleckenstein B, Bandyopadhyay A, Mellins ED, Sollid LM (2008)
Complexes of two cohorts of CLIP peptides and HLA-DQ2 of the autoimmune DR3-DQ2 haplotype are poor substrates for HLA-DM
J Immunol, 181 (8), 5451-5461
DOI 10.4049/jimmunol.181.8.5451, PubMed 18832702

Bergseng E, Sidney J, Sette A, Sollid LM (2008)
Analysis of the binding of gluten T-cell epitopes to various human leukocyte antigen class II molecules
Hum Immunol, 69 (2), 94-100
DOI 10.1016/j.humimm.2008.01.002, PubMed 18361933

Xia J, Bergseng E, Fleckenstein B, Siegel M, Kim CY, Khosla C, Sollid LM (2007)
Cyclic and dimeric gluten peptide analogues inhibiting DQ2-mediated antigen presentation in celiac disease
Bioorg Med Chem, 15 (20), 6565-73
DOI 10.1016/j.bmc.2007.07.001, PubMed 17681795

Ráki M, Fallang LE, Brottveit M, Bergseng E, Quarsten H, Lundin KE, Sollid LM (2007)
Tetramer visualization of gut-homing gluten-specific T cells in the peripheral blood of celiac disease patients
Proc Natl Acad Sci U S A, 104 (8), 2831-6
DOI 10.1073/pnas.0608610104, PubMed 17307878

Xia J, Siegel M, Bergseng E, Sollid LM, Khosla C (2006)
Inhibition of HLA-DQ2-mediated antigen presentation by analogues of a high affinity 33-residue peptide from alpha2-gliadin
J Am Chem Soc, 128 (6), 1859-67
DOI 10.1021/ja056423o, PubMed 16464085

Qiao SW, Bergseng E, Molberg O, Jung G, Fleckenstein B, Sollid LM (2005)
Refining the rules of gliadin T cell epitope binding to the disease-associated DQ2 molecule in celiac disease: importance of proline spacing and glutamine deamidation
J Immunol, 175 (1), 254-61
DOI 10.4049/jimmunol.175.1.254, PubMed 15972656

Bergseng E, Xia J, Kim CY, Khosla C, Sollid LM (2005)
Main chain hydrogen bond interactions in the binding of proline-rich gluten peptides to the celiac disease-associated HLA-DQ2 molecule
J Biol Chem, 280 (23), 21791-6
DOI 10.1074/jbc.M501558200, PubMed 15826953

Qiao SW, Bergseng E, Molberg Ø, Xia J, Fleckenstein B, Khosla C, Sollid LM (2004)
Antigen presentation to celiac lesion-derived T cells of a 33-mer gliadin peptide naturally formed by gastrointestinal digestion
J Immunol, 173 (3), 1757-62
DOI 10.4049/jimmunol.173.3.1757, PubMed 15265905

Kim CY, Quarsten H, Bergseng E, Khosla C, Sollid LM (2004)
Structural basis for HLA-DQ2-mediated presentation of gluten epitopes in celiac disease
Proc Natl Acad Sci U S A, 101 (12), 4175-9
DOI 10.1073/pnas.0306885101, PubMed 15020763

Theses

Bergseng E (2008)
Peptide binding to HLA-DQ2 and development of blocking agents for the treatment of celiac disease
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 673, 1 b. (flere pag.)
BIBSYS 082424977, ISBN 978-82-8072-750-3

Bergseng E (2002)
Formulering av et hydrokortisonpreparat med tids-kontrollert frisetting
E. Bergseng, Oslo, VI, 85 s.
BIBSYS 022346899