RSS feed

Publications by Yngvar Gundersen

54 publications found

Original articles

Castellani JW, Spitz MG, Karis AJ, Martini S, Young AJ, Margolis LM, Phillip Karl J, Murphy NE, Xu X, Montain SJ, Bohn JA, Teien HK, Stenberg PH, Gundersen Y, Pasiakos SM (2017)
Cardiovascular and thermal strain during 3-4 days of a metabolically demanding cold-weather military operation
Extrem Physiol Med, 6, 2
DOI 10.1186/s13728-017-0056-6, PubMed 28878888

Karl JP, Margolis LM, Madslien EH, Murphy NE, Castellani JW, Gundersen Y, Hoke AV, Levangie MW, Kumar R, Chakraborty N, Gautam A, Hammamieh R, Martini S, Montain SJ, Pasiakos SM (2017)
Changes in intestinal microbiota composition and metabolism coincide with increased intestinal permeability in young adults under prolonged physiological stress
Am J Physiol Gastrointest Liver Physiol, 312 (6), G559-G571
DOI 10.1152/ajpgi.00066.2017, PubMed 28336545

Strand-Amundsen RJ, Tronstad C, Kalvøy H, Gundersen Y, Krohn CD, Aasen AO, Holhjem L, Reims HM, Martinsen ØG, Høgetveit JO, Ruud TE, Tønnessen TI (2016)
In vivo characterization of ischemic small intestine using bioimpedance measurements
Physiol Meas, 37 (2), 257-75
DOI 10.1088/0967-3334/37/2/257, PubMed 26805916

Shegarfi H, Krohn CD, Gundersen Y, Kjeldsen SF, Hviid CV, Ruud TE, Aasen AO (2015)
Regulation of CCN1 (Cyr61) in a porcine model of intestinal ischemia/reperfusion
Innate Immun, 21 (5), 453-62
DOI 10.1177/1753425915569089, PubMed 25783840

Hagemo JS, Jørgensen JJ, Ostrowski SR, Holtan A, Gundersen Y, Johansson PI, Næss PA, Gaarder C (2013)
Changes in fibrinogen availability and utilization in an animal model of traumatic coagulopathy
Scand J Trauma Resusc Emerg Med, 21, 56
DOI 10.1186/1757-7241-21-56, PubMed 23867061

Ruud TE, Gundersen Y, Krohn CD, Sveen O, Aasen AO (2013)
Effects of infliximab and hydrocortisone on in vitro cytokine responses after stimulation with lipopolysaccharide
Surg Infect (Larchmt), 14 (1), 30-4
DOI 10.1089/sur.2011.093, PubMed 23425281

Lundeland B, Osterholt H, Gundersen Y, Opstad PK, Thrane I, Zhang Y, Olaussen RW, Vaagenes P (2012)
Moderate temperature alterations affect Gram-negative immune signalling in ex vivo whole blood
Scand J Clin Lab Invest, 72 (3), 246-52
DOI 10.3109/00365513.2012.657667, PubMed 22324831

Breivik T, Gundersen Y, Gjermo P, Taylor SM, Woodruff TM, Opstad PK (2011)
Oral treatment with complement factor C5a receptor (CD88) antagonists inhibits experimental periodontitis in rats
J Periodontal Res, 46 (6), 643-7
DOI 10.1111/j.1600-0765.2011.01383.x, PubMed 21722134

Breivik T, Gundersen Y, Gjermo P, Fristad I, Opstad PK (2011)
Systemic chemical desensitization of peptidergic sensory neurons with resiniferatoxin inhibits experimental periodontitis
Open Dent J, 5, 1-6
DOI 10.2174/1874210601105010001, PubMed 21339860

Lundeland B, Gundersen Y, Opstad PK, Thrane I, Zhang Y, Olaussen RW, Vaagenes P (2010)
Severe gunshot injuries in a porcine model: impact on central markers of innate immunity
Acta Anaesthesiol Scand, 55 (1), 28-34
DOI 10.1111/j.1399-6576.2010.02351.x, PubMed 21059178

Gundersen Y, Ruud TE, Krohn CD, Sveen O, Lyngstadaas SP, Aasen AO (2010)
Impact of hypertonic saline on the release of selected cytokines after stimulation with LPS or peptidoglycan in ex vivo whole blood from healthy humans
Shock, 34 (5), 450-4
DOI 10.1097/SHK.0b013e3181e68649, PubMed 20458267

Breivik T, Gundersen Y, Gjermo P, von Hörsten S, Opstad PK (2009)
Nicotinic acetylcholine receptor activation mediates nicotine-induced enhancement of experimental periodontitis
J Periodontal Res, 44 (3), 297-304
DOI 10.1111/j.1600-0765.2009.01223.x, PubMed 19453497

Breivik T, Gundersen Y, Gjermo P, von Hörsten S, Opstad PK (2009)
Nicotinic acetylcholine receptor activation mediates nicotine-induced enhancement of experimental periodontitis
J Periodontal Res, 44 (1), 110-6
DOI 10.1111/j.1600-0765.2008.01095.x, PubMed 18973546

Gundersen Y, Vaagenes P, Thrane I, Os Ø, Pillgram-Larsen J, Sundnes KO, Aasen AO, Opstad PK (2008)
Early time course of altered leukocyte response to lipopolysaccharide and peptidoglycan in porcine gunshot injury
Acta Anaesthesiol Scand, 52 (9), 1231-7
DOI 10.1111/j.1399-6576.2008.01754.x, PubMed 18823462

Tamandl D, Jørgensen P, Gundersen Y, Fuegger R, Sautner T, Aasen AO, Goetzinger P (2008)
Nitric oxide administration restores the hepatic artery buffer response during porcine endotoxemia
J Invest Surg, 21 (4), 183-94
DOI 10.1080/08941930802130131, PubMed 18615315

Ruud TE, Gundersen Y, Wang JE, Foster SJ, Thiemermann C, Aasen AO (2007)
Activation of cytokine synthesis by systemic infusions of lipopolysaccharide and peptidoglycan in a porcine model in vivo and in vitro
Surg Infect (Larchmt), 8 (5), 495-503
DOI 10.1089/sur.2006.083, PubMed 17999582

Gundersen Y, Vaagenes P, Os Ø, Pillgram-Larsen J, Sundnes KO, Opstad PK (2007)
Capacity of glycine to modulate early inflammatory disturbances after serious gunshot injuries in the pig
Scand J Clin Lab Invest, 67 (2), 143-53
DOI 10.1080/00365510600995226, PubMed 17365994

Breivik T, Gundersen Y, Myhrer T, Fonnum F, Osmundsen H, Murison R, Gjermo P, von Hörsten S, Opstad PK (2006)
Enhanced susceptibility to periodontitis in an animal model of depression: reversed by chronic treatment with the anti-depressant tianeptine
J Clin Periodontol, 33 (7), 469-77
DOI 10.1111/j.1600-051X.2006.00935.x, PubMed 16820034

Breivik T, Gundersen Y, Osmundsen H, Fonnum F, Opstad PK (2006)
Neonatal dexamethasone and chronic tianeptine treatment inhibit ligature-induced periodontitis in adult rats
J Periodontal Res, 41 (1), 23-32
DOI 10.1111/j.1600-0765.2005.00833.x, PubMed 16409252

Gundersen Y, Vaagenes P, Thrane I, Bogen IL, Haug KH, Reistad T, Opstad PK (2005)
Response of circulating immune cells to major gunshot injury, haemorrhage, and acute surgery
Injury, 36 (8), 949-55
DOI 10.1016/j.injury.2004.09.021, PubMed 15982652

Breivik T, Gundersen Y, Opstad PK, Fonnum F (2005)
Chemical sympathectomy inhibits periodontal disease in Fischer 344 rats
J Periodontal Res, 40 (4), 325-30
DOI 10.1111/j.1600-0765.2005.00803.x, PubMed 15966910

Gundersen Y, Vaagenes P, Thrane I, Sterri SH, Opstad PK (2005)
N-Acetylcysteine administered as part of the immediate post-traumatic resuscitation regimen does not significantly influence initiation of inflammatory responses or subsequent endotoxin hyporesponsiveness
Resuscitation, 64 (3), 377-82
DOI 10.1016/j.resuscitation.2004.09.005, PubMed 15733769

Breivik T, Gundersen Y, Fonnum F, Vaagenes P, Opstad PK (2005)
Chronic glycine treatment inhibits ligature-induced periodontal disease in Wistar rats
J Periodontal Res, 40 (1), 43-7
DOI 10.1111/j.1600-0765.2004.00767.x, PubMed 15613078

Breivik T, Gundersen Y, Osmundsen H, Opstad PK, Fonnum F (2005)
Chronic treatment with the glutamate receptor antagonist MK-801 alters periodontal disease susceptibility
J Periodontal Res, 40 (1), 28-35
DOI 10.1111/j.1600-0765.2004.00765.x, PubMed 15613076

Gundersen Y, Vaagenes P, Reistad T, Opstad PK (2003)
Modest protection of early hydrocortisone treatment in a rat model of volume-controlled haemorrhage
Acta Anaesthesiol Scand, 47 (9), 1165-71
DOI 10.1034/j.1399-6576.2003.00223.x, PubMed 12969113

Vaagenes P, Gundersen Y, Opstad PK (2003)
Rapid rewarming after mild hypothermia accentuates the inflammatory response after acute volume controlled haemorrhage in spontaneously breathing rats
Resuscitation, 58 (1), 103-12
DOI 10.1016/s0300-9572(03)00102-3, PubMed 12867316

Gundersen Y, Vaagenes P, Myhre O, Andersen JM (2003)
[Pharmacological modulation of the inflammatory response after gunshot injuries in the pig]
Tidsskr Nor Laegeforen, 123 (8), 1054-7
PubMed 12760219

Gundersen Y, Vaagenes P, Myhre O, Andersen JM, Pharo A, Haugen AH, Valoe E, Opstad PK (2003)
Hydrocortisone and the mitogen-activated protein kinase inhibitor U0126 acutely suppress reactive oxygen species generation from circulating granulocytes after gunshot injuries in the pig
Crit Care Med, 31 (1), 166-70
DOI 10.1097/00003246-200301000-00026, PubMed 12545011

Jørgensen PF, Götzinger P, Scholz T, Gundersen Y, Sautner T, Függer R, Lilleaasen P, Aasen AO (2001)
The role of Kupffer cell inhibition in porcine endotoxemia
Shock, 16 (6), 466-72
DOI 10.1097/00024382-200116060-00011, PubMed 11770046

Gundersen Y, Vaagenes P, Pharo A, Valø ET, Opstad PK (2001)
Moderate hypothermia blunts the inflammatory response and reduces organ injury after acute haemorrhage
Acta Anaesthesiol Scand, 45 (8), 994-1001
DOI 10.1034/j.1399-6576.2001.450812.x, PubMed 11576051

Gundersen Y, Vaagenes P (2001)
[Steroid treatment of shock lung--tune for re-evaluation?]
Tidsskr Nor Laegeforen, 121 (13), 1596-8
PubMed 11446045

Saetre T, Hovig T, Røger M, Gundersen Y, Aasen AO (2001)
Hepatocellular damage in porcine endotoxemia: beneficial effects of selective versus non-selective nitric oxide synthase inhibition?
Scand J Clin Lab Invest, 61 (7), 503-12
DOI 10.1080/003655101753218265, PubMed 11763408

Gundersen Y, Saetre T, Scholz T, Hovig T, Lilleaasen P, Aasen AO (1999)
Selective inhibition of inducible nitric oxide synthase maintains haemodynamic stability without untoward consequences for hepatic function or morphology
Eur J Surg, 165 (12), 1167-74
DOI 10.1080/110241599750007711, PubMed 10636552

Gundersen Y, Corso CO, Leiderer R, Dörger M, Lilleaasen P, Aasen AO, Messmer K (1998)
The nitric oxide donor sodium nitroprusside protects against hepatic microcirculatory dysfunction in early endotoxaemia
Intensive Care Med, 24 (12), 1257-63
DOI 10.1007/s001340050759, PubMed 9885877

Saetre T, Gundersen Y, Smiseth OA, Scholz T, Carlsen H, Nordsletten L, Lilleaasen P, Sautner T, Függer R, Aasen AO (1998)
Hepatic oxygen metabolism in porcine endotoxemia: the effect of nitric oxide synthase inhibition
Am J Physiol, 275 (6), G1377-85
DOI 10.1152/ajpgi.1998.275.6.G1377, PubMed 9843775

Saetre T, Gundersen Y, Thiemermann C, Lilleaasen P, Aasen AO (1998)
Aminoethyl-isothiourea, a selective inhibitor of inducible nitric oxide synthase activity, improves liver circulation and oxygen metabolism in a porcine model of endotoxemia
Shock, 9 (2), 109-15
DOI 10.1097/00024382-199802000-00006, PubMed 9488255

Corso CO, Gundersen Y, Dörger M, Lilleaasen P, Aasen AO, Messmer K (1998)
Effects of the nitric oxide synthase inhibitors N(G)-nitro-L-arginine methyl ester and aminoethyl-isothiourea on the liver microcirculation in rat endotoxemia
J Hepatol, 28 (1), 61-9
DOI 10.1016/s0168-8278(98)80203-1, PubMed 9537865

Gundersen Y, Corso CO, Leiderer R, Dörger M, Lilleaasen P, Aasen AO, Messmer K (1997)
Use of selective and nonselective nitric oxide synthase inhibitors in rat endotoxemia: effects on hepatic morphology and function
Shock, 8 (5), 368-72
DOI 10.1097/00024382-199711000-00009, PubMed 9361348

Gundersen Y, Saetre T, Carlsen H, Scholz T, Lilleaasen P, Aasen AO (1997)
Modulators of nitric oxide in porcine endotoxemia: effects on hepatic oxygen delivery and consumption
Eur Surg Res, 29 (4), 237-45
DOI 10.1159/000129529, PubMed 9257095

Gundersen Y, Saetre T, Scholz T, Carlsen H, Kjekshus H, Smiseth OA, Lilleaasen P, Aasen AO (1996)
The NO donor sodium nitroprusside reverses the negative effects on hepatic arterial flow induced by endotoxin and the NO synthase inhibitor L-NAME
Eur Surg Res, 28 (5), 323-32
DOI 10.1159/000129473, PubMed 8880121

Gundersen Y, Saetre T, Scholz T, Lilleaasen P, Aasen AO (1996)
Pre-treatment with the selective nitric oxide synthase inhibitor aminoethyl-isothiourea in porcine endotoxemia
4TH INTERNATIONAL CONGRESS ON THE IMMUNE CONSEQUENCES OF TRAUMA, SHOCK AND SEPSIS: MECHANISMS AND THERAPEUTIC APPROACHES, 975-978

Tølløfsrud SG, Gundersen Y, Andersen R (1984)
Peroperative hypothermia
Acta Anaesthesiol Scand, 28 (5), 511-5
DOI 10.1111/j.1399-6576.1984.tb02109.x, PubMed 6496010

Gundersen Y, Andersen R, Alver T (1984)
[Early postoperative treatment of pain with buprenorphine]
Tidsskr Nor Laegeforen, 104 (25), 1717-20
PubMed 6385337

Review articles

Gundersen Y, Vaagenes P, Reistad T, Opstad PK (2005)
[Brominated flame retardants may cause brain injuries in the fetus and the newborn]
Tidsskr Nor Laegeforen, 125 (22), 3098-100
PubMed 16299563

Gundersen Y, Vaagenes P, Dreiem A, Fonnum F (2004)
[Glycine]
Tidsskr Nor Laegeforen, 124 (6), 773-5
PubMed 15039805

Other articles

Gundersen Y, Vaagenes P (2003)
Re: Omert LA et al. Harbingers of poor outcome the day after severe brain injury: hypothermia, hypoxia, and hypoperfusion
J Trauma, 55 (2), 388-9
DOI 10.1097/01.TA.0000079248.12022.AF, PubMed 12913660

Books

Gundersen Y (2008)
Tidlige funksjonsendringer i sirkulerende hvite blodlegemer etter skuddskader hos gris: en kartlegging av tidsforløpet i ex vivo fullblod
FFI, Kjeller, 17 s.
BIBSYS 080375235, ISBN 978-82-464-1328-0

Gundersen Y (2008)
Markører for overbelastning under en fem-dagers fysisk krevende militærøvelse
Forsvarets forskningsinstitutt, Kjeller, 20 s.
BIBSYS 080973183, ISBN 978-82-464-1383-9

Gundersen Y (2007)
Hvordan påvirker temperaturen funksjonen i sirkulerende hvite blodlegemer
Forsvarets forskningsinstitutt, Kjeller, 15 s.
BIBSYS 080322921, ISBN 978-82-464-1308-2

Gundersen Y, Vaagenes P, Andersen JM, Dreiem A, Haugen AH, Myhre O, Reistad T, Sterri S, Thrane I (2003)
Glysin som del av det akutte resusciteringsregimet etter skuddskader hos gris: modulering av den tidlige inflammatoriske responsen
FFI, Kjeller, 20 s.
BIBSYS 030747864, ISBN 82-464-0696-5

Gundersen Y, Vaagenes P, Haugen AH, Pharo A, Valø ET, Myhre O, Andersen JM, Sundnes KO, Os Ø, Pillgram-Larsen J (2002)
Tidlig behandling med hydrokortison og/eller U-0126 hemmer syntesen av frie oksygenradikaler etter skuddskader hos gris
FFI, Kjeller, 16 s.
BIBSYS 020531664, ISBN 82-464-0581-0

Vaagenes P, Gundersen Y, Ærø CE (2000)
Aksidentell hypotermi og bruk av rotte som eksperimentellmodell
FFI, Kjeller, 18 s.
BIBSYS 00188624x, ISBN 82-464-0467-9

Gundersen Y (2000)
Kontrollert mild/moderat hypotermi ved blødningssjokk
FFI, Kjeller, 16 s.
BIBSYS 001886045, ISBN 82-464-0465-2

Theses

Gundersen Y (1999)
Modulation of nitric oxide values in endotoxaemia: an experimental study with special emphasis on liver circulation and function
Institute for Surgical Research, Klinikum Grosshadern, Ludwig-Maximilians-University, Munich, 1 b. (flere pag.)
BIBSYS 990901874, ISBN 82-7722-114-2