Publication list - Publika - Scientific publications from Oslo University Hospital

Publications by Dzung B. Diep

125 publications found

Original articles

Reinseth I, Diep DB, Kjos M, Tønnesen HH, Carlsen H (2024)
Exploring the feasibility of bacteriocins EntK1 and EntEJ97s in treatment of systemic vancomycin resistant enterococci infections in mice
J Appl Microbiol, 135 (3)
DOI 10.1093/jambio/lxae054, PubMed 38439668

Wolden R, Ovchinnikov KV, Venter HJ, Oftedal TF, Diep DB, Cavanagh JP (2023)
The novel bacteriocin romsacin from Staphylococcus haemolyticus inhibits Gram-positive WHO priority pathogens
Microbiol Spectr, 11 (6), e0086923
DOI 10.1128/spectrum.00869-23, PubMed 37905822

Kristensen SS, Lukassen MV, Siebenhaar S, Diep DB, Morth JP, Mathiesen G (2023)
Lactiplantibacillus plantarum as a novel platform for production and purification of integral membrane proteins using RseP as the benchmark
Sci Rep, 13 (1), 14361
DOI 10.1038/s41598-023-41559-7, PubMed 37658186

Oftedal TF, Diep DB (2023)
Flow cytometric detection of vancomycin-resistant Enterococcus faecium in urine using fluorescently labelled enterocin K1
Sci Rep, 13 (1), 10930
DOI 10.1038/s41598-023-38114-9, PubMed 37414859

Ormaasen I, Rudi K, Diep DB, Snipen L (2023)
Metagenome-mining indicates an association between bacteriocin presence and strain diversity in the infant gut
BMC Genomics, 24 (1), 295
DOI 10.1186/s12864-023-09388-0, PubMed 37259063

Escobedo S, Campelo AB, Umu ÖCO, López-González MJ, Rodríguez A, Diep DB, Martínez B (2023)
Resistance to the Bacteriocin Lcn972 Deciphered by Genome Sequencing
Microorganisms, 11 (2)
DOI 10.3390/microorganisms11020501, PubMed 36838466

Ovchinnikov KV, Kranjec C, Thorstensen T, Carlsen H, Diep DB (2022)
Bacteriocins Revitalize Non-Effective Penicillin G to Overcome Methicillin-Resistant Staphylococcus pseudintermedius
Antibiotics (Basel), 11 (12)
DOI 10.3390/antibiotics11121691, PubMed 36551348

Desiderato CK, Hasenauer KM, Reich SJ, Goldbeck O, Holivololona L, Ovchinnikov KV, Reiter A, Oldiges M, Diep DB, Eikmanns BJ, Riedel CU (2022)
Garvicin Q: characterization of biosynthesis and mode of action
Microb Cell Fact, 21 (1), 236
DOI 10.1186/s12934-022-01952-9, PubMed 36368990

Kristensen SS, Oftedal TF, Røhr ÅK, Eijsink VGH, Mathiesen G, Diep DB (2022)
The extracellular domain of site-2-metalloprotease RseP is important for sensitivity to bacteriocin EntK1
J Biol Chem, 298 (11), 102593
DOI 10.1016/j.jbc.2022.102593, PubMed 36244452

Ovchinnikov KV, Oftedal TF, Reich SJ, Bar NS, Holo H, Skaugen M, Riedel CU, Diep DB (2022)
Genome-assisted Identification, Purification, and Characterization of Bacteriocins
Bio Protoc, 12 (14)
DOI 10.21769/BioProtoc.4477, PubMed 35978579

Rosenbergová Z, Oftedal TF, Ovchinnikov KV, Thiyagarajah T, Rebroš M, Diep DB (2022)
Identification of a Novel Two-Peptide Lantibiotic from Vagococcus fluvialis
Microbiol Spectr, 10 (4), e0095422
DOI 10.1128/spectrum.00954-22, PubMed 35730941

Grønseth T, Ovchinnikov KV, Carlsen H, Benth JŠ, Diep DB, von Unge M, Silvola JT (2022)
Lugol's solution and Gentian violet eradicate methicillin-resistant Staphylococcus aureus biofilm in skin wound infections
Int Wound J, 20 (1), 120-130
DOI 10.1111/iwj.13846, PubMed 35633295

Dubey S, Diep DB, Evensen Ø, Munang'andu HM (2022)
Garvicin KS, a Broad-Spectrum Bacteriocin Protects Zebrafish Larvae against Lactococcus garvieae Infection
Int J Mol Sci, 23 (5)
DOI 10.3390/ijms23052833, PubMed 35269976

Weixler D, Berghoff M, Ovchinnikov KV, Reich S, Goldbeck O, Seibold GM, Wittmann C, Bar NS, Eikmanns BJ, Diep DB, Riedel CU (2022)
Recombinant production of the lantibiotic nisin using Corynebacterium glutamicum in a two-step process
Microb Cell Fact, 21 (1), 11
DOI 10.1186/s12934-022-01739-y, PubMed 35033086

Oftedal TF, Ovchinnikov KV, Hestad KA, Goldbeck O, Porcellato D, Narvhus J, Riedel CU, Kjos M, Diep DB (2021)
Ubericin K, a New Pore-Forming Bacteriocin Targeting mannose-PTS
Microbiol Spectr, 9 (2), e0029921
DOI 10.1128/Spectrum.00299-21, PubMed 34643411

Tymoszewska A, Ovchinnikov KV, Diep DB, Słodownik M, Maron E, Martínez B, Aleksandrzak-Piekarczyk T (2021)
Lactococcus lactis Resistance to Aureocin A53- and Enterocin L50-Like Bacteriocins and Membrane-Targeting Peptide Antibiotics Relies on the YsaCB-KinG-LlrG Four-Component System
Antimicrob Agents Chemother, 65 (12), e0092121
DOI 10.1128/AAC.00921-21, PubMed 34516250

Goldbeck O, Desef DN, Ovchinnikov KV, Perez-Garcia F, Christmann J, Sinner P, Crauwels P, Weixler D, Cao P, Becker J, Kohlstedt M, Kager J, Eikmanns BJ, Seibold GM, Herwig C, Wittmann C, Bar NS, Diep DB, Riedel CU (2021)
Establishing recombinant production of pediocin PA-1 in Corynebacterium glutamicum
Metab Eng, 68, 34-45
DOI 10.1016/j.ymben.2021.09.002, PubMed 34492380

Thapa RK, Winther-Larsen HC, Ovchinnikov K, Carlsen H, Diep DB, Tønnesen HH (2021)
Hybrid hydrogels for bacteriocin delivery to infected wounds
Eur J Pharm Sci, 166, 105990
DOI 10.1016/j.ejps.2021.105990, PubMed 34481880

Desiderato CK, Sachsenmaier S, Ovchinnikov KV, Stohr J, Jacksch S, Desef DN, Crauwels P, Egert M, Diep DB, Goldbeck O, Riedel CU (2021)
Identification of Potential Probiotics Producing Bacteriocins Active against Listeria monocytogenes by a Combination of Screening Tools
Int J Mol Sci, 22 (16)
DOI 10.3390/ijms22168615, PubMed 34445321

Kranjec C, Kristensen SS, Bartkiewicz KT, Brønner M, Cavanagh JP, Srikantam A, Mathiesen G, Diep DB (2021)
A bacteriocin-based treatment option for Staphylococcus haemolyticus biofilms
Sci Rep, 11 (1), 13909
DOI 10.1038/s41598-021-93158-z, PubMed 34230527

Ovchinnikov KV, Kranjec C, Telke A, Kjos M, Thorstensen T, Scherer S, Carlsen H, Diep DB (2021)
A Strong Synergy Between the Thiopeptide Bacteriocin Micrococcin P1 and Rifampicin Against MRSA in a Murine Skin Infection Model
Front Immunol, 12, 676534
DOI 10.3389/fimmu.2021.676534, PubMed 34276663

Reinseth I, Tønnesen HH, Carlsen H, Diep DB (2021)
Exploring the Therapeutic Potenital of the Leaderless Enterocins K1 and EJ97 in the Treatment of Vancomycin-Resistant Enterococcal Infection
Front Microbiol, 12, 649339
DOI 10.3389/fmicb.2021.649339, PubMed 33679682

Kranjec C, Ovchinnikov KV, Grønseth T, Ebineshan K, Srikantam A, Diep DB (2020)
A bacteriocin-based antimicrobial formulation to effectively disrupt the cell viability of methicillin-resistant Staphylococcus aureus (MRSA) biofilms
NPJ Biofilms Microbiomes, 6 (1), 58
DOI 10.1038/s41522-020-00166-4, PubMed 33268776

Thapa RK, Winther-Larsen HC, Diep DB, Tønnesen HH (2020)
Photostability studies of GarKS peptides for topical formulation development
Eur J Pharm Sci, 158, 105652
DOI 10.1016/j.ejps.2020.105652, PubMed 33248238

Ovchinnikov KV, Kranjec C, Thorstensen T, Carlsen H, Diep DB (2020)
Successful Development of Bacteriocins into Therapeutic Formulation for Treatment of MRSA Skin Infection in a Murine Model
Antimicrob Agents Chemother, 64 (12)
DOI 10.1128/AAC.00829-20, PubMed 32958719

Reinseth IS, Ovchinnikov KV, Tønnesen HH, Carlsen H, Diep DB (2020)
The Increasing Issue of Vancomycin-Resistant Enterococci and the Bacteriocin Solution
Probiotics Antimicrob Proteins, 12 (3), 1203-1217
DOI 10.1007/s12602-019-09618-6, PubMed 31758332

Umu ÖCO, Gueimonde M, Oostindjer M, Ovchinnikov KV, de Los Reyes-Gavilán CG, Arbulu S, Hernández PE, Martínez B, Diep DB, Salazar N (2020)
Use of Fecal Slurry Cultures to Study In Vitro Effects of Bacteriocins on the Gut Bacterial Populations of Infants
Probiotics Antimicrob Proteins, 12 (3), 1218-1225
DOI 10.1007/s12602-019-09614-w, PubMed 31788767

Thapa RK, Winther-Larsen HC, Diep DB, Tønnesen HH (2020)
Preformulation studies on novel garvicin KS peptides for topical applications
Eur J Pharm Sci, 151, 105333
DOI 10.1016/j.ejps.2020.105333, PubMed 32268197

Campanero C, Muñoz-Atienza E, Diep DB, Feito J, Arbulu S, Del Campo R, Nes IF, Hernández PE, Herranz C, Cintas LM (2020)
Biochemical, genetic and transcriptional characterization of multibacteriocin production by the anti-pneumococcal dairy strain Streptococcus infantarius LP90
PLoS One, 15 (3), e0229417
DOI 10.1371/journal.pone.0229417, PubMed 32134941

Antonsen S, Monsen EB, Ovchinnikov K, Nolsoe JMJ, Ekeberg D, Kristiansen JE, Diep DB, Stenstrom Y (2020)
Synthesis of the Enantiomers of Thioridazine
SynOpen, 4 (1), 12-16
DOI 10.1055/s-0039-1690834

Kubašová I, Diep DB, Ovchinnikov KV, Lauková A, Strompfová V (2019)
Bacteriocin production and distribution of bacteriocin-encoding genes in enterococci from dogs
Int J Antimicrob Agents, 55 (2), 105859
DOI 10.1016/j.ijantimicag.2019.11.016, PubMed 31794868

Gomez-Sala B, Munoz-Atienza E, Diep DB, Feito J, del Campo R, Nes IF, Herranz C, Hernandez PE, Cintas LM (2019)
Biotechnological potential and in vitro safety assessment of Lactobacillus curvatus BCS35, a multibacteriocinogenic strain isolated from dry-salted cod (Gadus morhua)
LWT-Food Sci. Technol., 112, 108219
DOI 10.1016/j.lwt.2019.05.117

Hagbø M, Ravi A, Angell IL, Sunde M, Ludvigsen J, Diep DB, Foley SL, Vento M, Collado MC, Perez-Martinez G, Rudi K (2019)
Experimental support for multidrug resistance transfer potential in the preterm infant gut microbiota
Pediatr Res, 88 (1), 57-65
DOI 10.1038/s41390-019-0491-8, PubMed 31261372

Telke AA, Ovchinnikov KV, Vuoristo KS, Mathiesen G, Thorstensen T, Diep DB (2019)
Over 2000-Fold Increased Production of the Leaderless Bacteriocin Garvicin KS by Increasing Gene Dose and Optimization of Culture Conditions
Front Microbiol, 10, 389
DOI 10.3389/fmicb.2019.00389, PubMed 30891018

Crauwels P, Schäfer L, Weixler D, Bar NS, Diep DB, Riedel CU, Seibold GM (2018)
Intracellular pHluorin as Sensor for Easy Assessment of Bacteriocin-Induced Membrane-Damage in Listeria monocytogenes
Front Microbiol, 9, 3038
DOI 10.3389/fmicb.2018.03038, PubMed 30619129

Tymoszewska A, Diep DB, Aleksandrzak-Piekarczyk T (2018)
The extracellular loop of Man-PTS subunit IID is responsible for the sensitivity of Lactococcus garvieae to garvicins A, B and C
Sci Rep, 8 (1), 15790
DOI 10.1038/s41598-018-34087-2, PubMed 30361679

Tymoszewska A, Diep DB, Wirtek P, Aleksandrzak-Piekarczyk T (2017)
The Non-Lantibiotic Bacteriocin Garvicin Q Targets Man-PTS in a Broad Spectrum of Sensitive Bacterial Genera
Sci Rep, 7 (1), 8359
DOI 10.1038/s41598-017-09102-7, PubMed 28827688

Bäuerl C, Umu ÖCO, Hernandez PE, Diep DB, Pérez-Martínez G (2017)
A Method to Assess Bacteriocin Effects on the Gut Microbiota of Mice
J Vis Exp (125)
DOI 10.3791/56053, PubMed 28784971

Ovchinnikov KV, Kristiansen PE, Straume D, Jensen MS, Aleksandrzak-Piekarczyk T, Nes IF, Diep DB (2017)
The Leaderless Bacteriocin Enterocin K1 Is Highly Potent against Enterococcus faecium: A Study on Structure, Target Spectrum and Receptor
Front Microbiol, 8, 774
DOI 10.3389/fmicb.2017.00774, PubMed 28515717

Mehmeti I, Bytyqi H, Muji S, Nes IF, Diep DB (2017)
The prevalence of Listeria monocytogenes and Staphylococcus aureus and their virulence genes in bulk tank milk in Kosovo
J Infect Dev Ctries, 11 (3), 247-254
DOI 10.3855/jidc.8256, PubMed 28368859

Mehmeti I, Behluli B, Mestani M, Ademi A, Nes IF, Diep DB (2016)
Antimicrobial resistance levels amongst staphylococci isolated from clinical cases of bovine mastitis in Kosovo
J Infect Dev Ctries, 10 (10), 1081-1087
DOI 10.3855/jidc.7912, PubMed 27801370

Umu ÖC, Bäuerl C, Oostindjer M, Pope PB, Hernández PE, Pérez-Martínez G, Diep DB (2016)
The Potential of Class II Bacteriocins to Modify Gut Microbiota to Improve Host Health
PLoS One, 11 (10), e0164036
DOI 10.1371/journal.pone.0164036, PubMed 27695121

Miljkovic M, Uzelac G, Mirkovic N, Devescovi G, Diep DB, Venturi V, Kojic M (2016)
LsbB Bacteriocin Interacts with the Third Transmembrane Domain of the YvjB Receptor
Appl Environ Microbiol, 82 (17), 5364-74
DOI 10.1128/AEM.01293-16, PubMed 27342562

Ovchinnikov KV, Chi H, Mehmeti I, Holo H, Nes IF, Diep DB (2016)
Novel Group of Leaderless Multipeptide Bacteriocins from Gram-Positive Bacteria
Appl Environ Microbiol, 82 (17), 5216-24
DOI 10.1128/AEM.01094-16, PubMed 27316965

Arbulu S, Jimenez JJ, Borrero J, Sánchez J, Frantzen C, Herranz C, Nes IF, Cintas LM, Diep DB, Hernández PE (2016)
Draft Genome Sequence of the Bacteriocinogenic Strain Enterococcus faecalis DBH18, Isolated from Mallard Ducks (Anas platyrhynchos)
Genome Announc, 4 (4)
DOI 10.1128/genomeA.00663-16, PubMed 27417838

Mirkovic N, Polovic N, Vukotic G, Jovcic B, Miljkovic M, Radulovic Z, Diep DB, Kojic M (2016)
Lactococcus lactis LMG2081 Produces Two Bacteriocins, a Nonlantibiotic and a Novel Lantibiotic
Appl Environ Microbiol, 82 (8), 2555-2562
DOI 10.1128/AEM.03988-15, PubMed 26896142

Arbulu S, Frantzen C, Lohans CT, Cintas LM, Herranz C, Holo H, Diep DB, Vederas JC, Hernández PE (2016)
Draft Genome Sequence of the Bacteriocin-Producing Strain Enterococcus faecium M3K31, Isolated from Griffon Vultures (Gyps fulvus subsp. fulvus)
Genome Announc, 4 (2)
DOI 10.1128/genomeA.00055-16, PubMed 27013035

Askarian F, Ajayi C, Hanssen AM, van Sorge NM, Pettersen I, Diep DB, Sollid JU, Johannessen M (2016)
The interaction between Staphylococcus aureus SdrD and desmoglein 1 is important for adhesion to host cells
Sci Rep, 6, 22134
DOI 10.1038/srep22134, PubMed 26924733

Jiménez JJ, Diep DB, Borrero J, Gútiez L, Arbulu S, Nes IF, Herranz C, Cintas LM, Hernández PE (2015)
Cloning strategies for heterologous expression of the bacteriocin enterocin A by Lactobacillus sakei Lb790, Lb. plantarum NC8 and Lb. casei CECT475
Microb Cell Fact, 14, 166
DOI 10.1186/s12934-015-0346-x, PubMed 26471395

Hassan M, Brede DA, Diep DB, Nes IF, Lotfipour F, Hojabri Z (2015)
Efficient Inactivation of Multi-Antibiotics Resistant Nosocomial Enterococci by Purified Hiracin Bacteriocin
Adv Pharm Bull, 5 (3), 393-401
DOI 10.15171/apb.2015.054, PubMed 26504762

Mehmeti I, Muji S, Diep DB, Nes IF (2015)
High frequency of the potential pathogen Lactococcus garvieae in raw milk from Kosovo
Food Control, 53, 189-194
DOI 10.1016/j.foodcont.2015.01.024

Umu ÖC, Frank JA, Fangel JU, Oostindjer M, da Silva CS, Bolhuis EJ, Bosch G, Willats WG, Pope PB, Diep DB (2015)
Resistant starch diet induces change in the swine microbiome and a predominance of beneficial bacterial populations
Microbiome, 3, 16
DOI 10.1186/s40168-015-0078-5, PubMed 25905018

Porcellato D, Frantzen C, Rangberg A, Umu OC, Gabrielsen C, Nes IF, Amdam GV, Diep DB (2015)
Draft Genome Sequence of Lactobacillus kunkeei AR114 Isolated from Honey Bee Gut
Genome Announc, 3 (2)
DOI 10.1128/genomeA.00144-15, PubMed 25792062

La Rosa SL, Snipen LG, Murray BE, Willems RJ, Gilmore MS, Diep DB, Nes IF, Brede DA (2015)
A genomic virulence reference map of Enterococcus faecalis reveals an important contribution of phage03-like elements in nosocomial genetic lineages to pathogenicity in a Caenorhabditis elegans infection model
Infect Immun, 83 (5), 2156-67
DOI 10.1128/IAI.02801-14, PubMed 25776747

Dundar H, Brede DA, La Rosa SL, El-Gendy AO, Diep DB, Nes IF (2015)
The fsr Quorum-Sensing System and Cognate Gelatinase Orchestrate the Expression and Processing of Proprotein EF_1097 into the Mature Antimicrobial Peptide Enterocin O16
J Bacteriol, 197 (13), 2112-2121
DOI 10.1128/JB.02513-14, PubMed 25733609

La Rosa SL, Solheim M, Diep DB, Nes IF, Brede DA (2015)
Bioluminescence based biosensors for quantitative detection of enterococcal peptide-pheromone activity reveal inter-strain telesensing in vivo during polymicrobial systemic infection
Sci Rep, 5, 8339
DOI 10.1038/srep08339, PubMed 25661457

Rangberg A, Mathiesen G, Amdam GV, Diep DB (2015)
The paratransgenic potential of Lactobacillus kunkeei in the honey bee Apis mellifera
Benef Microbes, 6 (4), 513-23
DOI 10.3920/BM2014.0115, PubMed 25609652

Ovchinnikov KV, Kristiansen PE, Uzelac G, Topisirovic L, Kojic M, Nissen-Meyer J, Nes IF, Diep DB (2014)
Defining the structure and receptor binding domain of the leaderless bacteriocin LsbB
J Biol Chem, 289 (34), 23838-45
DOI 10.1074/jbc.M114.579698, PubMed 24993828

Kjos M, Oppegård C, Diep DB, Nes IF, Veening JW, Nissen-Meyer J, Kristensen T (2014)
Sensitivity to the two-peptide bacteriocin lactococcin G is dependent on UppP, an enzyme involved in cell-wall synthesis
Mol Microbiol, 92 (6), 1177-87
DOI 10.1111/mmi.12632, PubMed 24779486

Gabrielsen C, Brede DA, Salehian Z, Nes IF, Diep DB (2013)
Functional genetic analysis of the GarML gene cluster in Lactococcus garvieae DCC43 gives new insights into circular bacteriocin biosynthesis
J Bacteriol, 196 (5), 911-9
DOI 10.1128/JB.01115-13, PubMed 24336941

Uzelac G, Kojic M, Lozo J, Aleksandrzak-Piekarczyk T, Gabrielsen C, Kristensen T, Nes IF, Diep DB, Topisirovic L (2013)
A Zn-dependent metallopeptidase is responsible for sensitivity to LsbB, a class II leaderless bacteriocin of Lactococcus lactis subsp. lactis BGMN1-5
J Bacteriol, 195 (24), 5614-21
DOI 10.1128/JB.00859-13, PubMed 24123824

Jiménez JJ, Borrero J, Diep DB, Gútiez L, Nes IF, Herranz C, Cintas LM, Hernández PE (2013)
Cloning, production, and functional expression of the bacteriocin sakacin A (SakA) and two SakA-derived chimeras in lactic acid bacteria (LAB) and the yeasts Pichia pastoris and Kluyveromyces lactis
J Ind Microbiol Biotechnol, 40 (9), 977-93
DOI 10.1007/s10295-013-1302-6, PubMed 23794087

La Rosa SL, Casey PG, Hill C, Diep DB, Nes IF, Brede DA (2013)
In vivo assessment of growth and virulence gene expression during commensal and pathogenic lifestyles of luxABCDE-tagged Enterococcus faecalis strains in murine gastrointestinal and intravenous infection models
Appl Environ Microbiol, 79 (13), 3986-97
DOI 10.1128/AEM.00831-13, PubMed 23603680

Gabrielsen C, Brede DA, Hernández PE, Nes IF, Diep DB (2012)
Genome sequence of the bacteriocin-producing strain Lactococcus garvieae DCC43
J Bacteriol, 194 (24), 6976-7
DOI 10.1128/JB.01864-12, PubMed 23209230

La Rosa SL, Diep DB, Nes IF, Brede DA (2012)
Construction and application of a luxABCDE reporter system for real-time monitoring of Enterococcus faecalis gene expression and growth
Appl Environ Microbiol, 78 (19), 7003-11
DOI 10.1128/AEM.02018-12, PubMed 22843522

Rangberg A, Diep DB, Rudi K, Amdam GV (2012)
Paratransgenesis: an approach to improve colony health and molecular insight in honey bees (Apis mellifera)?
Integr Comp Biol, 52 (1), 89-99
DOI 10.1093/icb/ics089, PubMed 22659204

Hassan M, Diep DB, Javadzadeh Y, Dastmalchi S, Nes IF, Sharifi Y, Yari S, Farajnia S, Lotfipour F (2012)
Prevalence of bacteriocin activities and bacteriocin-encoding genes in enterococcal clinical isolates in Iran
Can J Microbiol, 58 (4), 359-68
DOI 10.1139/w11-136, PubMed 22414091

Gabrielsen C, Brede DA, Hernández PE, Nes IF, Diep DB (2012)
The maltose ABC transporter in Lactococcus lactis facilitates high-level sensitivity to the circular bacteriocin garvicin ML
Antimicrob Agents Chemother, 56 (6), 2908-15
DOI 10.1128/AAC.00314-12, PubMed 22411612

Kjos M, Nes IF, Diep DB (2011)
Mechanisms of resistance to bacteriocins targeting the mannose phosphotransferase system
Appl Environ Microbiol, 77 (10), 3335-42
DOI 10.1128/AEM.02602-10, PubMed 21421780

Borrero J, Brede DA, Skaugen M, Diep DB, Herranz C, Nes IF, Cintas LM, Hernández PE (2010)
Characterization of garvicin ML, a novel circular bacteriocin produced by Lactococcus garvieae DCC43, isolated from mallard ducks (Anas platyrhynchos)
Appl Environ Microbiol, 77 (1), 369-73
DOI 10.1128/AEM.01173-10, PubMed 21057028

Kjos M, Salehian Z, Nes IF, Diep DB (2010)
An extracellular loop of the mannose phosphotransferase system component IIC is responsible for specific targeting by class IIa bacteriocins
J Bacteriol, 192 (22), 5906-13
DOI 10.1128/JB.00777-10, PubMed 20870773

Bøhle LA, Brede DA, Diep DB, Holo H, Nes IF (2010)
Specific degradation of the mucus adhesion-promoting protein (MapA) of Lactobacillus reuteri to an antimicrobial peptide
Appl Environ Microbiol, 76 (21), 7306-9
DOI 10.1128/AEM.01423-10, PubMed 20833791

Basanta A, Gómez-Sala B, Sánchez J, Diep DB, Herranz C, Hernández PE, Cintas LM (2010)
Use of the yeast Pichia pastoris as an expression host for secretion of enterocin L50, a leaderless two-peptide (L50A and L50B) bacteriocin from Enterococcus faecium L50
Appl Environ Microbiol, 76 (10), 3314-24
DOI 10.1128/AEM.02206-09, PubMed 20348300

Kjos M, Snipen L, Salehian Z, Nes IF, Diep DB (2010)
The abi proteins and their involvement in bacteriocin self-immunity
J Bacteriol, 192 (8), 2068-76
DOI 10.1128/JB.01553-09, PubMed 20154137

Straume D, Johansen RF, Bjørås M, Nes IF, Diep DB (2009)
DNA binding kinetics of two response regulators, PlnC and PlnD, from the bacteriocin regulon of Lactobacillus plantarum C11
BMC Biochem, 10, 17
DOI 10.1186/1471-2091-10-17, PubMed 19519894

Kjos M, Nes IF, Diep DB (2009)
Class II one-peptide bacteriocins target a phylogenetically defined subgroup of mannose phosphotransferase systems on sensitive cells
Microbiology (Reading), 155 (Pt 9), 2949-2961
DOI 10.1099/mic.0.030015-0, PubMed 19477899

Hildrestrand GA, Neurauter CG, Diep DB, Castellanos CG, Krauss S, Bjørås M, Luna L (2009)
Expression patterns of Neil3 during embryonic brain development and neoplasia
BMC Neurosci, 10, 45
DOI 10.1186/1471-2202-10-45, PubMed 19426544

Kjos M, Straume D, Nes IF, Diep DB (2008)
Transposition of IS10R in Lactococcus lactis
J Appl Microbiol, 106 (1), 288-95
DOI 10.1111/j.1365-2672.2008.04002.x, PubMed 19120617

Straume D, Kjos M, Nes IF, Diep DB (2007)
Quorum-sensing based bacteriocin production is down-regulated by N-terminally truncated species of gene activators
Mol Genet Genomics, 278 (3), 283-93
DOI 10.1007/s00438-007-0251-z, PubMed 17576598

Sánchez J, Diep DB, Herranz C, Nes IF, Cintas LM, Hernández PE (2007)
Amino acid and nucleotide sequence, adjacent genes, and heterologous expression of hiracin JM79, a sec-dependent bacteriocin produced by Enterococcus hirae DCH5, isolated from Mallard ducks (Anas platyrhynchos)
FEMS Microbiol Lett, 270 (2), 227-36
DOI 10.1111/j.1574-6968.2007.00673.x, PubMed 17326750

Diep DB, Skaugen M, Salehian Z, Holo H, Nes IF (2007)
Common mechanisms of target cell recognition and immunity for class II bacteriocins
Proc Natl Acad Sci U S A, 104 (7), 2384-9
DOI 10.1073/pnas.0608775104, PubMed 17284603

Hildrestrand GA, Diep DB, Kunke D, Bolstad N, Bjørås M, Krauss S, Luna L (2007)
The capacity to remove 8-oxoG is enhanced in newborn neural stem/progenitor cells and decreases in juvenile mice and upon cell differentiation
DNA Repair (Amst), 6 (6), 723-32
DOI 10.1016/j.dnarep.2006.12.008, PubMed 17236821

Fujimura N, Vacik T, Machon O, Vlcek C, Scalabrin S, Speth M, Diep D, Krauss S, Kozmik Z (2006)
Wnt-mediated down-regulation of Sp1 target genes by a transcriptional repressor Sp5
J Biol Chem, 282 (2), 1225-37
DOI 10.1074/jbc.M605851200, PubMed 17090534

Criado R, Diep DB, Aakra A, Gutiérrez J, Nes IF, Hernández PE, Cintas LM (2006)
Complete sequence of the enterocin Q-encoding plasmid pCIZ2 from the multiple bacteriocin producer Enterococcus faecium L50 and genetic characterization of enterocin Q production and immunity
Appl Environ Microbiol, 72 (10), 6653-66
DOI 10.1128/AEM.00859-06, PubMed 17021217

Diep DB, Godager L, Brede D, Nes IF (2006)
Data mining and characterization of a novel pediocin-like bacteriocin system from the genome of Pediococcus pentosaceus ATCC 25745
Microbiology (Reading), 152 (Pt 6), 1649-1659
DOI 10.1099/mic.0.28794-0, PubMed 16735728

Straume D, Axelsson L, Nes IF, Diep DB (2006)
Improved expression and purification of the correctly folded response regulator PlnC from lactobacilli
J Microbiol Methods, 67 (2), 193-201
DOI 10.1016/j.mimet.2006.03.022, PubMed 16712990

Diep DB, Hoen N, Backman M, Machon O, Krauss S (2004)
Characterisation of the Wnt antagonists and their response to conditionally activated Wnt signalling in the developing mouse forebrain
Brain Res Dev Brain Res, 153 (2), 261-70
DOI 10.1016/j.devbrainres.2004.09.008, PubMed 15527894

Rappa G, Kunke D, Holter J, Diep DB, Meyer J, Baum C, Fodstad O, Krauss S, Lorico A (2004)
Efficient expansion and gene transduction of mouse neural stem/progenitor cells on recombinant fibronectin
Neuroscience, 124 (4), 823-30
DOI 10.1016/j.neuroscience.2003.11.030, PubMed 15026123

Johnsborg O, Diep DB, Nes IF (2003)
Structural analysis of the peptide pheromone receptor PlnB, a histidine protein kinase from Lactobacillus plantarum
J Bacteriol, 185 (23), 6913-20
DOI 10.1128/JB.185.23.6913-6920.2003, PubMed 14617655

Diep DB, Myhre R, Johnsborg O, Aakra A, Nes IF (2003)
Inducible bacteriocin production in Lactobacillus is regulated by differential expression of the pln operons and by two antagonizing response regulators, the activity of which is enhanced upon phosphorylation
Mol Microbiol, 47 (2), 483-94
DOI 10.1046/j.1365-2958.2003.03310.x, PubMed 12519198

Burr SE, Diep DB, Buckley JT (2001)
Type II secretion by Aeromonas salmonicida: evidence for two periplasmic pools of proaerolysin
J Bacteriol, 183 (20), 5956-63
DOI 10.1128/JB.183.20.5956-5963.2001, PubMed 11566995

Diep DB, Johnsborg O, Risøen PA, Nes IF (2001)
Evidence for dual functionality of the operon plnABCD in the regulation of bacteriocin production in Lactobacillus plantarum
Mol Microbiol, 41 (3), 633-44
DOI 10.1046/j.1365-2958.2001.02533.x, PubMed 11532131

Risøen PA, Johnsborg O, Diep DB, Hamoen L, Venema G, Nes IF (2001)
Regulation of bacteriocin production in Lactobacillus plantarum depends on a conserved promoter arrangement with consensus binding sequence
Mol Genet Genomics, 265 (1), 198-206
DOI 10.1007/s004380000397, PubMed 11370867

Diep DB, Axelsson L, Grefsli C, Nes IF (2000)
The synthesis of the bacteriocin sakacin A is a temperature-sensitive process regulated by a pheromone peptide through a three-component regulatory system
Microbiology (Reading), 146 ( Pt 9), 2155-2160
DOI 10.1099/00221287-146-9-2155, PubMed 10974103

Diep DB, Nelson KL, Lawrence TS, Sellman BR, Tweten RK, Buckley JT (1999)
Expression and properties of an aerolysin--Clostridium septicum alpha toxin hybrid protein
Mol Microbiol, 31 (3), 785-94
DOI 10.1046/j.1365-2958.1999.01217.x, PubMed 10048023

Diep DB, Lawrence TS, Ausio J, Howard SP, Buckley JT (1998)
Secretion and properties of the large and small lobes of the channel-forming toxin aerolysin
Mol Microbiol, 30 (2), 341-52
DOI 10.1046/j.1365-2958.1998.01068.x, PubMed 9791179

Risøen PA, Håvarstein LS, Diep DB, Nes IF (1998)
Identification of the DNA-binding sites for two response regulators involved in control of bacteriocin synthesis in Lactobacillus plantarum C11
Mol Gen Genet, 259 (2), 224-32
DOI 10.1007/pl00008627, PubMed 9747714

Anderssen EL, Diep DB, Nes IF, Eijsink VG, Nissen-Meyer J (1998)
Antagonistic activity of Lactobacillus plantarum C11: two new two-peptide bacteriocins, plantaricins EF and JK, and the induction factor plantaricin A
Appl Environ Microbiol, 64 (6), 2269-72
DOI 10.1128/AEM.64.6.2269-2272.1998, PubMed 9603847

Diep DB, Nelson KL, Raja SM, Pleshak EN, Buckley JT (1998)
Glycosylphosphatidylinositol anchors of membrane glycoproteins are binding determinants for the channel-forming toxin aerolysin
J Biol Chem, 273 (4), 2355-60
DOI 10.1074/jbc.273.4.2355, PubMed 9442081

Nes IF, Diep DB, Håvarstein LS, Brurberg MB, Eijsink V, Holo H (1996)
Biosynthesis of bacteriocins in lactic acid bacteria
Antonie Van Leeuwenhoek, 70 (2-4), 113-28
DOI 10.1007/BF00395929, PubMed 8879403

Diep DB, Håvarstein LS, Nes IF (1996)
Characterization of the locus responsible for the bacteriocin production in Lactobacillus plantarum C11
J Bacteriol, 178 (15), 4472-83
DOI 10.1128/jb.178.15.4472-4483.1996, PubMed 8755874

Diep DB, Håvarstein LS, Nes IF (1995)
A bacteriocin-like peptide induces bacteriocin synthesis in Lactobacillus plantarum C11
Mol Microbiol, 18 (4), 631-9
DOI 10.1111/j.1365-2958.1995.mmi_18040631.x, PubMed 8817486

Håvarstein LS, Diep DB, Nes IF (1995)
A family of bacteriocin ABC transporters carry out proteolytic processing of their substrates concomitant with export
Mol Microbiol, 16 (2), 229-40
DOI 10.1111/j.1365-2958.1995.tb02295.x, PubMed 7565085

Kjærulff S, Diep DB, Okkels JS, Scheller HV, Ormerod JG (1994)
Highly efficient integration of foreign DNA into the genome of the green sulfur bacterium,Chlorobium vibrioforme by homologous recombination
Photosynth Res, 41 (1), 277-83
DOI 10.1007/BF02184168, PubMed 24310034

Diep DB, Håvarstein LS, Nissen-Meyer J, Nes IF (1994)
The gene encoding plantaricin A, a bacteriocin from Lactobacillus plantarum C11, is located on the same transcription unit as an agr-like regulatory system
Appl Environ Microbiol, 60 (1), 160-6
DOI 10.1128/aem.60.1.160-166.1994, PubMed 8117074

Review articles

Kristensen SS, Diep DB, Kjos M, Mathiesen G (2023)
The role of site-2-proteases in bacteria: a review on physiology, virulence, and therapeutic potential
Microlife, 4, uqad025
DOI 10.1093/femsml/uqad025, PubMed 37223736

Kumar V, Singh B, van Belkum MJ, Diep DB, Chikindas ML, Ermakov AM, Tiwari SK (2021)
Halocins, natural antimicrobials of Archaea: Exotic or special or both?
Biotechnol Adv, 53, 107834
DOI 10.1016/j.biotechadv.2021.107834, PubMed 34509601

Thapa RK, Diep DB, Tonnesen HH (2021)
Nanomedicine-based antimicrobial peptide delivery for bacterial infections: recent advances and future prospects
J. Pharm. Investig., 51 (4), 377-398
DOI 10.1007/s40005-021-00525-z

Kranjec C, Morales Angeles D, Torrissen Mårli M, Fernández L, García P, Kjos M, Diep DB (2021)
Staphylococcal Biofilms: Challenges and Novel Therapeutic Perspectives
Antibiotics (Basel), 10 (2)
DOI 10.3390/antibiotics10020131, PubMed 33573022

Thapa RK, Diep DB, Tønnesen HH (2019)
Topical antimicrobial peptide formulations for wound healing: Current developments and future prospects
Acta Biomater, 103, 52-67
DOI 10.1016/j.actbio.2019.12.025, PubMed 31874224

Umu ÖCO, Rudi K, Diep DB (2017)
Modulation of the gut microbiota by prebiotic fibres and bacteriocins
Microb Ecol Health Dis, 28 (1), 1348886
DOI 10.1080/16512235.2017.1348886, PubMed 28959178

Gabrielsen C, Brede DA, Nes IF, Diep DB (2014)
Circular bacteriocins: biosynthesis and mode of action
Appl Environ Microbiol, 80 (22), 6854-62
DOI 10.1128/AEM.02284-14, PubMed 25172850

Umu OC, Oostindjer M, Pope PB, Svihus B, Egelandsdal B, Nes IF, Diep DB (2013)
Potential applications of gut microbiota to control human physiology
Antonie Van Leeuwenhoek, 104 (5), 609-18
DOI 10.1007/s10482-013-0008-0, PubMed 23975514

Hassan M, Kjos M, Nes IF, Diep DB, Lotfipour F (2012)
Natural antimicrobial peptides from bacteria: characteristics and potential applications to fight against antibiotic resistance
J Appl Microbiol, 113 (4), 723-36
DOI 10.1111/j.1365-2672.2012.05338.x, PubMed 22583565

Kjos M, Borrero J, Opsata M, Birri DJ, Holo H, Cintas LM, Snipen L, Hernández PE, Nes IF, Diep DB (2011)
Target recognition, resistance, immunity and genome mining of class II bacteriocins from Gram-positive bacteria
Microbiology (Reading), 157 (Pt 12), 3256-3267
DOI 10.1099/mic.0.052571-0, PubMed 21980118

Diep DB, Straume D, Kjos M, Torres C, Nes IF (2009)
An overview of the mosaic bacteriocin pln loci from Lactobacillus plantarum
Peptides, 30 (8), 1562-74
DOI 10.1016/j.peptides.2009.05.014, PubMed 19465075

Diep DB, Mathiesen G, Eijsink VG, Nes IF (2009)
Use of lactobacilli and their pheromone-based regulatory mechanism in gene expression and drug delivery
Curr Pharm Biotechnol, 10 (1), 62-73
DOI 10.2174/138920109787048571, PubMed 19149590

Nes IF, Yoon SS, Diep DB (2007)
Ribosomally synthesiszed antimicrobial peptides (Bacteriocins) in lactic acid bacteria: A review
Food Sci. Biotechnol., 16 (5), 675-690

Nes IF, Diep DB, Holo H (2006)
Bacteriocin diversity in Streptococcus and Enterococcus
J Bacteriol, 189 (4), 1189-98
DOI 10.1128/JB.01254-06, PubMed 17098898

Eijsink VG, Axelsson L, Diep DB, Håvarstein LS, Holo H, Nes IF (2002)
Production of class II bacteriocins by lactic acid bacteria; an example of biological warfare and communication
Antonie Van Leeuwenhoek, 81 (1-4), 639-54
DOI 10.1023/a:1020582211262, PubMed 12448760

Diep DB, Nes IF (2002)
Ribosomally synthesized antibacterial peptides in Gram positive bacteria
Curr Drug Targets, 3 (2), 107-22
DOI 10.2174/1389450024605409, PubMed 11958295