Publications 2018

Aqrawi LA, Jensen JL, Øijordsbakken G, Ruus AK, Nygård S, Holden M, Jonsson R, Galtung HK, Skarstein K (2018)
Signalling pathways identified in salivary glands from primary Sjögren's syndrome patients reveal enhanced adipose tissue development
Autoimmunity, 51 (3), 135-146
DOI 10.1080/08916934.2018.1446525, PubMed 29504848

Brynildsen J, Petäjä L, Pettilä V, Nygård S, Vaara ST, Linko R, Okkonen M, Hagve TA, Soininen L, Suojaranta-Ylinen R, Lyngbakken MN, Omland T, Røsjø H (2018)
The predictive value of NT-proBNP and hs-TnT for risk of death in cardiac surgical patients
Clin Biochem, 53, 65-71
DOI 10.1016/j.clinbiochem.2018.01.012, PubMed 29371002

Braadland PR, Giskeødegård G, Sandsmark E, Bertilsson H, Euceda LR, Hansen AF, Guldvik IJ, Selnæs KM, Grytli HH, Katz B, Svindland A, Bathen TF, Eri LM, Nygård S, Berge V, Taskén KA, Tessem MB (2018)
Ex vivo metabolic fingerprinting identifies biomarkers predictive of prostate cancer recurrence following radical prostatectomy
Br J Cancer, 118 (6), e11
DOI 10.1038/bjc.2017.470, PubMed 29462127

Dominguez Del Angel V, Hjerde E, Sterck L, Capella-Gutierrez S, Notredame C, Vinnere Pettersson O, Amselem J, Bouri L, Bocs S, Klopp C, Gibrat JF, Vlasova A, Leskosek BL, Soler L, Binzer-Panchal M, Lantz H (2018)
Ten steps to get started in Genome Assembly and Annotation
F1000Res, 7
DOI 10.12688/f1000research.13598.1, PubMed 29568489

Esaiassen E, Hjerde E, Cavanagh JP, Pedersen T, Andresen JH, Rettedal SI, Støen R, Nakstad B, Willassen NP, Klingenberg C (2018)
Effects of Probiotic Supplementation on the Gut Microbiota and Antibiotic Resistome Development in Preterm Infants
Front Pediatr, 6, 347
DOI 10.3389/fped.2018.00347, PubMed 30505830

Ihle-Hansen H, Vigen T, Ihle-Hansen H, Rønning OM, Berge T, Thommessen B, Lyngbakken MN, Orstad EB, Enger S, Nygård S, Røsjø H, Tveit A (2018)
Prevalence of Carotid Plaque in a 63- to 65-Year-Old Norwegian Cohort From the General Population: The ACE (Akershus Cardiac Examination) 1950 Study
J Am Heart Assoc, 7 (10)
DOI 10.1161/JAHA.118.008562, PubMed 29739796

Kanduri C, Bock C, Gundersen S, Hovig E, Sandve GK (2018)
Colocalization analyses of genomic elements: approaches, recommendations and challenges
Bioinformatics (in press)
DOI 10.1093/bioinformatics/bty835, PubMed 30307532

Nakken S, Fournous G, Vodák D, Aasheim LB, Myklebost O, Hovig E (2018)
Personal Cancer Genome Reporter: variant interpretation report for precision oncology
Bioinformatics, 34 (10), 1778-1780
DOI 10.1093/bioinformatics/btx817, PubMed 29272339

Simovski B, Kanduri C, Gundersen S, Titov D, Domanska D, Bock C, Bossini-Castillo L, Chikina M, Favorov A, Layer RM, Mironov AA, Quinlan AR, Sheffield NC, Trynka G, Sandve GK (2018)
Coloc-stats: a unified web interface to perform colocalization analysis of genomic features
Nucleic Acids Res, 46 (W1), W186-W193
DOI 10.1093/nar/gky474, PubMed 29873782

Tekle KM, Gundersen S, Klepper K, Bongo LA, Raknes IA, Li X, Zhang W, Andreetta C, Mulugeta TD, Kalaš M, Rye MB, Hjerde E, Antony Samy JK, Fornous G, Azab A, Våge DI, Hovig E, Willassen NP, Drabløs F, Nygård S, Petersen K, Jonassen I (2018)
Norwegian e-Infrastructure for Life Sciences (NeLS)
F1000Res, 7
DOI 10.12688/f1000research.15119.1, PubMed 30271575

Tunsjø HS, Kalyanasundaram S, Charnock C, Leegaard TM, Moen AEF (2018)
Challenges in the identification of methicillin-resistant Staphylococcus argenteus by routine diagnostics
APMIS, 126 (6), 533-537
DOI 10.1111/apm.12843, PubMed 29924450

Vodák D, Lorenz S, Nakken S, Aasheim LB, Holte H, Bai B, Myklebost O, Meza-Zepeda LA, Hovig E (2018)
Sample-Index Misassignment Impacts Tumour Exome Sequencing
Sci Rep, 8 (1), 5307
DOI 10.1038/s41598-018-23563-4, PubMed 29593270

Publications 2017

Andreassen R, Woldemariam NT, Egeland IØ, Agafonov O, Sindre H, Høyheim B (2017)
Identification of differentially expressed Atlantic salmon miRNAs responding to salmonid alphavirus (SAV) infection
BMC Genomics, 18 (1), 349
DOI 10.1186/s12864-017-3741-3, PubMed 28472924

Braadland PR, Giskeødegård G, Sandsmark E, Bertilsson H, Euceda LR, Hansen AF, Guldvik IJ, Selnæs KM, Grytli HH, Katz B, Svindland A, Bathen TF, Eri LM, Nygård S, Berge V, Taskén KA, Tessem MB (2017)
Ex vivo metabolic fingerprinting identifies biomarkers predictive of prostate cancer recurrence following radical prostatectomy
Br J Cancer, 117 (11), 1656-1664
DOI 10.1038/bjc.2017.346, PubMed 28972967

de Vries EMG, Färkkilä M, Milkiewicz P, Hov JR, Eksteen B, Thorburn D, Chazouillères O, Pares A, Nygård S, Gilja OH, Wunsch E, Invernizzi P, Carbone M, Bernuzzi F, Boberg KM, Røsjø H, Rosenberg W, Beuers UH, Ponsioen CY, Karlsen TH, Vesterhus M (2017)
Enhanced liver fibrosis test predicts transplant-free survival in primary sclerosing cholangitis, a multi-centre study
Liver Int, 37 (10), 1554-1561
DOI 10.1111/liv.13402, PubMed 28267887

Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C, Norwegian Study Group on Invasive Bifidobacterial Infections (2017)
Bifidobacterium Bacteremia: Clinical Characteristics and a Genomic Approach To Assess Pathogenicity
J Clin Microbiol, 55 (7), 2234-2248
DOI 10.1128/JCM.00150-17, PubMed 28490487

Hansen MF, Johansen J, Sylvander AE, Bjørnevoll I, Talseth-Palmer BA, Lavik LAS, Xavier A, Engebretsen LF, Scott RJ, Drabløs F, Sjursen W (2017)
Use of multigene-panel identifies pathogenic variants in several CRC-predisposing genes in patients previously tested for Lynch Syndrome
Clin Genet, 92 (4), 405-414
DOI 10.1111/cge.12994, PubMed 28195393

Karlsen C, Hjerde E, Klemetsen T, Willassen NP (2017)
Pan genome and CRISPR analyses of the bacterial fish pathogen Moritella viscosa
BMC Genomics, 18 (1), 313
DOI 10.1186/s12864-017-3693-7, PubMed 28427330

Landfors M, Johansen J, Aronsen JM, Vågbø CB, Doré LC, He C, Sjaastad I, Sætrom P, Fedorcsák P, Dahl JA, Aanes H, Fußer M, Klungland A (2017)
Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation
Cell Discov, 3, 17013
DOI 10.1038/celldisc.2017.13, PubMed 28529766

Meisal R, Rounge TB, Christiansen IK, Eieland AK, Worren MM, Molden TF, Kommedal Ø, Hovig E, Leegaard TM, Ambur OH (2017)
HPV Genotyping of Modified General Primer-Amplicons Is More Analytically Sensitive and Specific by Sequencing than by Hybridization
PLoS One, 12 (1), e0169074
DOI 10.1371/journal.pone.0169074, PubMed 28045981

Myhre PL, Stridsberg M, Linko R, Okkonen M, Nygård S, Christensen G, Pettilä V, Omland T, Røsjø H, FINNALI Study Group (2017)
Circulating chromogranin B levels in patients with acute respiratory failure: data from the FINNALI Study
Biomarkers, 22 (8), 775-781
DOI 10.1080/1354750X.2016.1269200, PubMed 28049363

Olsen MB, Hildrestrand GA, Scheffler K, Vinge LE, Alfsnes K, Palibrk V, Wang J, Neurauter CG, Luna L, Johansen J, Øgaard JDS, Ohm IK, Slupphaug G, Kuśnierczyk A, Fiane AE, Brorson SH, Zhang L, Gullestad L, Louch WE, Iversen PO, Østlie I, Klungland A, Christensen G, Sjaastad I, Sætrom P et al. (2017)
NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture
Cell Rep, 18 (1), 82-92
DOI 10.1016/j.celrep.2016.12.009, PubMed 28052262

Ree AH, Russnes HG, Heinrich D, Dueland S, Boye K, Nygaard V, Silwal-Pandit L, Østrup O, Hovig E, Nygaard V, Rødland EA, Nakken S, Øien JT, Johansen C, Bergheim IR, Skarpeteig V, Sathermugathevan M, Sauer T, Lund-Iversen M, Beiske K, Nasser S, Julsrud L, Reisse CH, Ruud EA, Flørenes VA et al. (2017)
Implementing precision cancer medicine in the public health services of Norway: the diagnostic infrastructure and a cost estimate
ESMO Open, 2 (2), e000158
DOI 10.1136/esmoopen-2017-000158, PubMed 28761742

Strøm TB, Laerdahl JK, Leren TP (2017)
Mutations affecting the transmembrane domain of the LDL receptor: impact of charged residues on the membrane insertion
Hum Mol Genet, 26 (9), 1634-1642
DOI 10.1093/hmg/ddx068, PubMed 28334946

Søberg K, Moen LV, Skålhegg BS, Laerdahl JK (2017)
Evolution of the cAMP-dependent protein kinase (PKA) catalytic subunit isoforms
PLoS One, 12 (7), e0181091
DOI 10.1371/journal.pone.0181091, PubMed 28742821

Thode SK, Bækkedal C, Söderberg JJ, Hjerde E, Hansen H, Haugen P (2017)
Construction of a fur null mutant and RNA-sequencing provide deeper global understanding of the Aliivibrio salmonicida Fur regulon
PeerJ, 5, e3461
DOI 10.7717/peerj.3461, PubMed 28717590

Vesterhus M, Holm A, Hov JR, Nygård S, Schrumpf E, Melum E, Thorbjørnsen LW, Paulsen V, Lundin K, Dale I, Gilja OH, Zweers SJLB, Vatn M, Schaap FG, Jansen PLM, Ueland T, Røsjø H, Moum B, Ponsioen CY, Boberg KM, Färkkilä M, Karlsen TH, Lund-Johansen F (2017)
Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis
J Hepatol, 66 (6), 1214-1222
DOI 10.1016/j.jhep.2017.01.019, PubMed 28161472

Volchenkov R, Nygaard V, Sener Z, Skålhegg BS (2017)
Th17 Polarization under Hypoxia Results in Increased IL-10 Production in a Pathogen-Independent Manner
Front Immunol, 8, 698
DOI 10.3389/fimmu.2017.00698, PubMed 28674533

Winther JA, Brynildsen J, Høiseth AD, Strand H, Følling I, Christensen G, Nygård S, Røsjø H, Omland T (2017)
Prognostic and diagnostic significance of copeptin in acute exacerbation of chronic obstructive pulmonary disease and acute heart failure: data from the ACE 2 study
Respir Res, 18 (1), 184
DOI 10.1186/s12931-017-0665-z, PubMed 29100503

Publications 2016

Andreassen R, Rangnes F, Sivertsen M, Chiang M, Tran M, Worren MM (2016)
Discovery of miRNAs and Their Corresponding miRNA Genes in Atlantic Cod (Gadus morhua): Use of Stable miRNAs as Reference Genes Reveals Subgroups of miRNAs That Are Highly Expressed in Particular Organs
PLoS One, 11 (4), e0153324
DOI 10.1371/journal.pone.0153324, PubMed 27128807

Fang EF, Kassahun H, Croteau DL, Scheibye-Knudsen M, Marosi K, Lu H, Shamanna RA, Kalyanasundaram S, Bollineni RC, Wilson MA, Iser WB, Wollman BN, Morevati M, Li J, Kerr JS, Lu Q, Waltz TB, Tian J, Sinclair DA, Mattson MP, Nilsen H, Bohr VA (2016)
NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair
Cell Metab, 24 (4), 566-581
DOI 10.1016/j.cmet.2016.09.004, PubMed 27732836

Ferrante L, Rognum TO, Vege Å, Nygård S, Opdal SH (2016)
Altered gene expression and possible immunodeficiency in cases of sudden infant death syndrome
Pediatr Res, 80 (1), 77-84
DOI 10.1038/pr.2016.45, PubMed 26959483

Kummen M, Holm K, Anmarkrud JA, Nygård S, Vesterhus M, Høivik ML, Trøseid M, Marschall HU, Schrumpf E, Moum B, Røsjø H, Aukrust P, Karlsen TH, Hov JR (2016)
The gut microbial profile in patients with primary sclerosing cholangitis is distinct from patients with ulcerative colitis without biliary disease and healthy controls
Gut, 66 (4), 611-619
DOI 10.1136/gutjnl-2015-310500, PubMed 26887816

Lyngbakken MN, Røsjø H, Holmen OL, Nygård S, Dalen H, Hveem K, Omland T (2016)
Gender, High-Sensitivity Troponin I, and the Risk of Cardiovascular Events (from the Nord-Trøndelag Health Study)
Am J Cardiol, 118 (6), 816-821
DOI 10.1016/j.amjcard.2016.06.043, PubMed 27453509

Lyngbakken MN, Skranes JB, de Lemos JA, Nygård S, Dalen H, Hveem K, Røsjø H, Omland T (2016)
Impact of Smoking on Circulating Cardiac Troponin I Concentrations and Cardiovascular Events in the General Population: The HUNT Study (Nord-Trøndelag Health Study)
Circulation, 134 (24), 1962-1972
DOI 10.1161/CIRCULATIONAHA.116.023726, PubMed 27815376

Moen MN, Fjær R, Hamdani EH, Laerdahl JK, Menchini RJ, Vigeland MD, Sheng Y, Undlien DE, Hassel B, Salih MA, El Khashab HY, Selmer KK, Chaudhry FA (2016)
Pathogenic variants in KCTD7 perturb neuronal K+ fluxes and glutamine transport
Brain, 139 (Pt 12), 3109-3120
DOI 10.1093/brain/aww244, PubMed 27742667

Munkley J, Vodak D, Livermore KE, James K, Wilson BT, Knight B, Mccullagh P, Mcgrath J, Crundwell M, Harries LW, Leung HY, Robson CN, Mills IG, Rajan P, Elliott DJ (2016)
Glycosylation is an Androgen-Regulated Process Essential for Prostate Cancer Cell Viability
EBioMedicine, 8, 103-116
DOI 10.1016/j.ebiom.2016.04.018, PubMed 27428423

Myhre PL, Ottesen AH, Okkonen M, Linko R, Stridsberg M, Nygård S, Christensen G, Pettilä V, Omland T, Røsjø H, FINNALI Laboratory Study Group (2016)
Prognostic Value of Secretoneurin in Patients with Acute Respiratory Failure: Data from the FINNALI Study
Clin Chem, 62 (10), 1380-9
DOI 10.1373/clinchem.2016.258764, PubMed 27540029

Røsjø H, Stridsberg M, Ottesen AH, Nygård S, Christensen G, Pettilä V, Linko R, Karlsson S, Varpula T, Ruokonen E, Omland T, FINNSEPSIS and FINNALI Study Groups (2016)
Prognostic Value of Secretoneurin in Critically Ill Patients With Infections
Crit Care Med, 44 (10), 1882-90
DOI 10.1097/CCM.0000000000001832, PubMed 27414477

Tunsjø HS, Kalyanasundaram S, Worren MM, Leegaard TM, Moen AEF (2016)
High frequency of occupied attB regions in Norwegian Staphylococcus aureus isolates supports a two-step MRSA screening algorithm
Eur J Clin Microbiol Infect Dis, 36 (1), 65-74
DOI 10.1007/s10096-016-2771-0, PubMed 27638009

Williamson A, De Santi C, Altermark B, Karlsen C, Hjerde E (2016)
Complete genome sequence of Halomonas sp. R5-57
Stand Genomic Sci, 11 (1), 62
DOI 10.1186/s40793-016-0192-4, PubMed 27610212

Publications 2015

Alioto TS, Buchhalter I, Derdak S, Hutter B, Eldridge MD, Hovig E, Heisler LE, Beck TA, Simpson JT, Tonon L, Sertier AS, Patch AM, Jäger N, Ginsbach P, Drews R, Paramasivam N, Kabbe R, Chotewutmontri S, Diessl N, Previti C, Schmidt S, Brors B, Feuerbach L, Heinold M, Gröbner S et al. (2015)
A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing
Nat Commun, 6, 10001
DOI 10.1038/ncomms10001, PubMed 26647970

Hansen MF, Johansen J, Bjørnevoll I, Sylvander AE, Steinsbekk KS, Sætrom P, Sandvik AK, Drabløs F, Sjursen W (2015)
A novel POLE mutation associated with cancers of colon, pancreas, ovaries and small intestine
Fam Cancer, 14 (3), 437-48
DOI 10.1007/s10689-015-9803-2, PubMed 25860647

Hjerde E, Karlsen C, Sørum H, Parkhill J, Willassen NP, Thomson NR (2015)
Co-cultivation and transcriptome sequencing of two co-existing fish pathogens Moritella viscosa and Aliivibrio wodanis
BMC Genomics, 16, 447
DOI 10.1186/s12864-015-1669-z, PubMed 26059548

Landin MA, Nygård S, Shabestari MG, Babaie E, Reseland JE, Osmundsen H (2015)
Mapping the global mRNA transcriptome during development of the murine first molar
Front Genet, 6, 47
DOI 10.3389/fgene.2015.00047, PubMed 25852735

Lau C, Nygård S, Fure H, Olstad OK, Holden M, Lappegård KT, Brekke OL, Espevik T, Hovig E, Mollnes TE (2015)
CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray
PLoS One, 10 (2), e0117261
DOI 10.1371/journal.pone.0117261, PubMed 25706641

Lau C, Olstad OK, Holden M, Nygård S, Fure H, Lappegård KT, Brekke OL, Espevik T, Hovig E, Mollnes TE (2015)
Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response
Genom Data, 5, 176-83
DOI 10.1016/j.gdata.2015.05.019, PubMed 26484252

Munkley J, Oltean S, Vodák D, Wilson BT, Livermore KE, Zhou Y, Star E, Floros VI, Johannessen B, Knight B, McCullagh P, McGrath J, Crundwell M, Skotheim RI, Robson CN, Leung HY, Harries LW, Rajan P, Mills IG, Elliott DJ (2015)
The androgen receptor controls expression of the cancer-associated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer
Oncotarget, 6 (33), 34358-74
DOI 10.18632/oncotarget.6024, PubMed 26452038

Omland T, de Lemos JA, Holmen OL, Dalen H, Benth JŠ, Nygård S, Hveem K, Røsjø H (2015)
Impact of sex on the prognostic value of high-sensitivity cardiac troponin I in the general population: the HUNT study
Clin Chem, 61 (4), 646-56
DOI 10.1373/clinchem.2014.234369, PubMed 25695851

Ricanek P, Lunde LK, Frye SA, Støen M, Nygård S, Morth JP, Rydning A, Vatn MH, Amiry-Moghaddam M, Tønjum T (2015)
Reduced expression of aquaporins in human intestinal mucosa in early stage inflammatory bowel disease
Clin Exp Gastroenterol, 8, 49-67
DOI 10.2147/CEG.S70119, PubMed 25624769

Ringh M, Rosenqvist M, Hollenberg J, Jonsson M, Fredman D, Nordberg P, Järnbert-Pettersson H, Hasselqvist-Ax I, Riva G, Svensson L (2015)
Mobile-phone dispatch of laypersons for CPR in out-of-hospital cardiac arrest
N Engl J Med, 372 (24), 2316-25
DOI 10.1056/NEJMoa1406038, PubMed 26061836

Rustad EH, Dai HY, Hov H, Coward E, Beisvag V, Myklebost O, Hovig E, Nakken S, Vodák D, Meza-Zepeda LA, Sandvik AK, Wader KF, Misund K, Sundan A, Aarset H, Waage A (2015)
BRAF V600E mutation in early-stage multiple myeloma: good response to broad acting drugs and no relation to prognosis
Blood Cancer J, 5, e299
DOI 10.1038/bcj.2015.24, PubMed 25794135

Sevilla LM, Latorre V, Carceller E, Boix J, Vodák D, Mills IG, Pérez P (2015)
Glucocorticoid receptor and Klf4 co-regulate anti-inflammatory genes in keratinocytes
Mol Cell Endocrinol, 412, 281-9
DOI 10.1016/j.mce.2015.05.015, PubMed 26001834

Simpson MR, Brede G, Johansen J, Johnsen R, Storrø O, Sætrom P, Øien T (2015)
Human Breast Milk miRNA, Maternal Probiotic Supplementation and Atopic Dermatitis in Offspring
PLoS One, 10 (12), e0143496
DOI 10.1371/journal.pone.0143496, PubMed 26657066

Stangeland B, Mughal AA, Grieg Z, Sandberg CJ, Joel M, Nygård S, Meling T, Murrell W, Vik Mo EO, Langmoen IA (2015)
Combined expressional analysis, bioinformatics and targeted proteomics identify new potential therapeutic targets in glioblastoma stem cells
Oncotarget, 6 (28), 26192-215
DOI 10.18632/oncotarget.4613, PubMed 26295306

Strøm TB, Laerdahl JK, Leren TP (2015)
Mutation p.L799R in the LDLR, which affects the transmembrane domain of the LDLR, prevents membrane insertion and causes secretion of the mutant LDLR
Hum Mol Genet, 24 (20), 5836-44
DOI 10.1093/hmg/ddv304, PubMed 26220972

Vesterhus M, Hov JR, Holm A, Schrumpf E, Nygård S, Godang K, Andersen IM, Naess S, Thorburn D, Saffioti F, Vatn M, Gilja OH, Lund-Johansen F, Syversveen T, Brabrand K, Parés A, Ponsioen CY, Pinzani M, Färkkilä M, Moum B, Ueland T, Røsjø H, Rosenberg W, Boberg KM, Karlsen TH (2015)
Enhanced liver fibrosis score predicts transplant-free survival in primary sclerosing cholangitis
Hepatology, 62 (1), 188-97
DOI 10.1002/hep.27825, PubMed 25833813

Williamson A, Hjerde E, Kahlke T (2015)
Analysis of the distribution and evolution of the ATP-dependent DNA ligases of bacteria delineates a distinct phylogenetic group 'Lig E'
Mol Microbiol, 99 (2), 274-90
DOI 10.1111/mmi.13229, PubMed 26412580

Publications 2014

Bergseng E, Dørum S, Arntzen MØ, Nielsen M, Nygård S, Buus S, de Souza GA, Sollid LM (2014)
Different binding motifs of the celiac disease-associated HLA molecules DQ2.5, DQ2.2, and DQ7.5 revealed by relative quantitative proteomics of endogenous peptide repertoires
Immunogenetics, 67 (2), 73-84
DOI 10.1007/s00251-014-0819-9, PubMed 25502872

Bjerga GE, Hjerde E, De Santi C, Williamson AK, Smalås AO, Willassen NP, Altermark B (2014)
High quality draft genome sequence of Streptomyces sp. strain AW19M42 isolated from a sea squirt in Northern Norway
Stand Genomic Sci, 9 (3), 676-86
DOI 10.4056/sigs.5038901, PubMed 25197453

Bjerga GEK, Hjerde E, De Santi C, Williamson AK, Smalas AO, Willassen NP, Altermark B (2014)
High quality draft genome sequence of Streptomyces sp. strain AW19M42 isolated from a sea squirt in Northern Norway
Stand. Genomic Sci., 9 (3)

Cavanagh JP, Hjerde E, Holden MT, Kahlke T, Klingenberg C, Flægstad T, Parkhill J, Bentley SD, Sollid JU (2014)
Whole-genome sequencing reveals clonal expansion of multiresistant Staphylococcus haemolyticus in European hospitals
J Antimicrob Chemother, 69 (11), 2920-7
DOI 10.1093/jac/dku271, PubMed 25038069

Haugum K, Johansen J, Gabrielsen C, Brandal LT, Bergh K, Ussery DW, Drabløs F, Afset JE (2014)
Comparative genomics to delineate pathogenic potential in non-O157 Shiga toxin-producing Escherichia coli (STEC) from patients with and without haemolytic uremic syndrome (HUS) in Norway
PLoS One, 9 (10), e111788
DOI 10.1371/journal.pone.0111788, PubMed 25360710

Hillestad V, Espe EK, Cero F, Larsen KO, Sjaastad I, Nygård S, Skjønsberg OH, Christensen G (2014)
IL-18 neutralization during alveolar hypoxia improves left ventricular diastolic function in mice
Acta Physiol (Oxf), 213 (2), 492-504
DOI 10.1111/apha.12376, PubMed 25182570

Kashulin A, Sørum H, Hjerde E, Willassen NP (2014)
IS elements in Aliivibrio salmonicida LFI1238: occurrence, variability and impact on adaptability
Gene, 554 (1), 40-9
DOI 10.1016/j.gene.2014.10.019, PubMed 25447025

Mærk M, Johansen J, Ertesvåg H, Drabløs F, Valla S (2014)
Safety in numbers: multiple occurrences of highly similar homologs among Azotobacter vinelandii carbohydrate metabolism proteins probably confer adaptive benefits
BMC Genomics, 15, 192
DOI 10.1186/1471-2164-15-192, PubMed 24625193

Nygård S, Reitan T, Clancy T, Nygaard V, Bjørnstad J, Skrbic B, Tønnessen T, Christensen G, Hovig E (2014)
Identifying pathogenic processes by integrating microarray data with prior knowledge
BMC Bioinformatics, 15, 115
DOI 10.1186/1471-2105-15-115, PubMed 24758699

Paulsen J, Sandve GK, Gundersen S, Lien TG, Trengereid K, Hovig E (2014)
HiBrowse: multi-purpose statistical analysis of genome-wide chromatin 3D organization
Bioinformatics, 30 (11), 1620-2
DOI 10.1093/bioinformatics/btu082, PubMed 24511080

Strøm TB, Tveten K, Laerdahl JK, Leren TP (2014)
Mutation G805R in the transmembrane domain of the LDL receptor gene causes familial hypercholesterolemia by inducing ectodomain cleavage of the LDL receptor in the endoplasmic reticulum
FEBS Open Bio, 4, 321-7
DOI 10.1016/j.fob.2014.03.007, PubMed 24918045

Wollen EJ, Kwinta P, Bik-Multanowski M, Madetko-Talowska A, Sejersted Y, Wright MS, Günther CC, Nygård S, Saugstad OD, Pietrzyk JJ (2014)
Hypoxia-reoxygenation affects whole-genome expression in the newborn eye
Invest Ophthalmol Vis Sci, 55 (3), 1393-401
DOI 10.1167/iovs.13-13159, PubMed 24458145

Wu X, Sagave J, Rutkovskiy A, Haugen F, Baysa A, Nygård S, Czibik G, Dahl CP, Gullestad L, Vaage J, Valen G (2014)
Expression of bone morphogenetic protein 4 and its receptors in the remodeling heart
Life Sci, 97 (2), 145-54
DOI 10.1016/j.lfs.2013.12.030, PubMed 24398041

Zeissig S, Petersen BS, Tomczak M, Melum E, Huc-Claustre E, Dougan SK, Laerdahl JK, Stade B, Forster M, Schreiber S, Weir D, Leichtner AM, Franke A, Blumberg RS (2014)
Early-onset Crohn's disease and autoimmunity associated with a variant in CTLA-4
Gut, 64 (12), 1889-97
DOI 10.1136/gutjnl-2014-308541, PubMed 25367873

Publications 2013

Andreassen R, Worren MM, Høyheim B (2013)
Discovery and characterization of miRNA genes in Atlantic salmon (Salmo salar) by use of a deep sequencing approach
BMC Genomics, 14, 482
DOI 10.1186/1471-2164-14-482, PubMed 23865519

Backe PH, Simm R, Laerdahl JK, Dalhus B, Fagerlund A, Okstad OA, Rognes T, Alseth I, Kolstø AB, Bjørås M (2013)
A new family of proteins related to the HEAT-like repeat DNA glycosylases with affinity for branched DNA structures
J Struct Biol, 183 (1), 66-75
DOI 10.1016/j.jsb.2013.04.007, PubMed 23623903

Bjørkeng EK, Hjerde E, Pedersen T, Sundsfjord A, Hegstad K (2013)
ICESluvan, a 94-kilobase mosaic integrative conjugative element conferring interspecies transfer of VanB-type glycopeptide resistance, a novel bacitracin resistance locus, and a toxin-antitoxin stabilization system
J Bacteriol, 195 (23), 5381-90
DOI 10.1128/JB.02165-12, PubMed 24078615

Clancy T, Rødland EA, Nygard S, Hovig E (2013)
Predicting physical interactions between protein complexes
Mol Cell Proteomics, 12 (6), 1723-34
DOI 10.1074/mcp.O112.019828, PubMed 23438732

Ellinghaus D, Folseraas T, Holm K, Ellinghaus E, Melum E, Balschun T, Laerdahl JK, Shiryaev A, Gotthardt DN, Weismüller TJ, Schramm C, Wittig M, Bergquist A, Björnsson E, Marschall HU, Vatn M, Teufel A, Rust C, Gieger C, Wichmann HE, Runz H, Sterneck M, Rupp C, Braun F, Weersma RK et al. (2013)
Genome-wide association analysis in primary sclerosing cholangitis and ulcerative colitis identifies risk loci at GPR35 and TCF4
Hepatology, 58 (3), 1074-83
DOI 10.1002/hep.25977, PubMed 22821403

Hjerde E, Pierechod MM, Williamson AK, Bjerga GE, Willassen NP, Smalås AO, Altermark B (2013)
Draft Genome Sequence of the Actinomycete Rhodococcus sp. Strain AW25M09, Isolated from the Hadsel Fjord, Northern Norway
Genome Announc, 1 (2), e0005513
DOI 10.1128/genomeA.00055-13, PubMed 23516194

Lewin A, Johansen J, Wentzel A, Kotlar HK, Drabløs F, Valla S (2013)
The microbial communities in two apparently physically separated deep subsurface oil reservoirs show extensive DNA sequence similarities
Environ Microbiol, 16 (2), 545-58
DOI 10.1111/1462-2920.12181, PubMed 23827055

Sandve GK, Gundersen S, Johansen M, Glad IK, Gunathasan K, Holden L, Holden M, Liestøl K, Nygård S, Nygaard V, Paulsen J, Rydbeck H, Trengereid K, Clancy T, Drabløs F, Ferkingstad E, Kalas M, Lien T, Rye MB, Frigessi A, Hovig E (2013)
The Genomic HyperBrowser: an analysis web server for genome-scale data
Nucleic Acids Res, 41 (Web Server issue), W133-41
DOI 10.1093/nar/gkt342, PubMed 23632163

Schee K, Lorenz S, Worren MM, Günther CC, Holden M, Hovig E, Fodstad O, Meza-Zepeda LA, Flatmark K (2013)
Deep Sequencing the MicroRNA Transcriptome in Colorectal Cancer
PLoS One, 8 (6), e66165
DOI 10.1371/journal.pone.0066165, PubMed 23824282

Søberg K, Jahnsen T, Rognes T, Skålhegg BS, Laerdahl JK (2013)
Evolutionary paths of the cAMP-dependent protein kinase (PKA) catalytic subunits
PLoS One, 8 (4), e60935
DOI 10.1371/journal.pone.0060935, PubMed 23593352

Vistnes M, Høiseth AD, Røsjø H, Nygård S, Pettersen E, Søyseth V, Hurlen P, Christensen G, Omland T (2013)
Lack of pro-inflammatory cytokine mobilization predicts poor prognosis in patients with acute heart failure
Cytokine, 61 (3), 962-9
DOI 10.1016/j.cyto.2013.01.006, PubMed 23415671

Wollen EJ, Sejersted Y, Wright MS, Bik-Multanowski M, Madetko-Talowska A, Günther CC, Nygård S, Kwinta P, Pietrzyk JJ, Saugstad OD (2013)
Transcriptome profiling of the newborn mouse lung after hypoxia and reoxygenation: hyperoxic reoxygenation affects mTOR signaling pathway, DNA repair, and JNK-pathway regulation
Pediatr Res, 74 (5), 536-44
DOI 10.1038/pr.2013.140, PubMed 23999071

Wollen EJ, Sejersted Y, Wright MS, Madetko-Talowska A, Bik-Multanowski M, Kwinta P, Günther CC, Nygård S, Løberg EM, Ystgaard MB, Pietrzyk JJ, Saugstad OD (2013)
Transcriptome profiling of the newborn mouse brain after hypoxia-reoxygenation: hyperoxic reoxygenation induces inflammatory and energy failure responsive genes
Pediatr Res, 75 (4), 517-26
DOI 10.1038/pr.2013.249, PubMed 24375083

Zegeye ED, Balasingham SV, Laerdahl JK, Homberset H, Kristiansen PE, Tønjum T (2013)
Effects of conserved residues and naturally occurring mutations on Mycobacterium tuberculosis RecG helicase activity
Microbiology, 160 (Pt 1), 217-227
DOI 10.1099/mic.0.072140-0, PubMed 24169816

Publications 2012

Ahmad R, Hansen GÅ, Hansen H, Hjerde E, Pedersen HL, Paulsen SM, Nyrud ML, Strauss A, Willassen NP, Haugen P (2012)
Prediction, microarray and northern blot analyses identify new intergenic small RNAs in Aliivibrio salmonicida
J Mol Microbiol Biotechnol, 22 (6), 352-60
DOI 10.1159/000345769, PubMed 23295256

Balasingham SV, Zegeye ED, Homberset H, Rossi ML, Laerdahl JK, Bohr VA, Tønjum T (2012)
Enzymatic activities and DNA substrate specificity of Mycobacterium tuberculosis DNA helicase XPB
PLoS One, 7 (5), e36960
DOI 10.1371/journal.pone.0036960, PubMed 22615856

Bjornsdottir B, Hjerde E, Bragason BT, Gudmundsdottir T, Willassen NP, Gudmundsdottir BK (2012)
Identification of type VI secretion systems in Moritella viscosa
Vet Microbiol, 158 (3-4), 436-42
DOI 10.1016/j.vetmic.2012.02.030, PubMed 22425489

Folseraas T, Melum E, Rausch P, Juran BD, Ellinghaus E, Shiryaev A, Laerdahl JK, Ellinghaus D, Schramm C, Weismüller TJ, Gotthardt DN, Hov JR, Clausen OP, Weersma RK, Janse M, Boberg KM, Björnsson E, Marschall HU, Cleynen I, Rosenstiel P, Holm K, Teufel A, Rust C, Gieger C, Wichmann HE et al. (2012)
Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci
J Hepatol, 57 (2), 366-75
DOI 10.1016/j.jhep.2012.03.031, PubMed 22521342

Hansen GA, Ahmad R, Hjerde E, Fenton CG, Willassen NP, Haugen P (2012)
Expression profiling reveals Spot 42 small RNA as a key regulator in the central metabolism of Aliivibrio salmonicida
BMC Genomics, 13, 37
DOI 10.1186/1471-2164-13-37, PubMed 22272603

Kahlke T, Goesmann A, Hjerde E, Willassen NP, Haugen P (2012)
Unique core genomes of the bacterial family vibrionaceae: insights into niche adaptation and speciation
BMC Genomics, 13, 179
DOI 10.1186/1471-2164-13-179, PubMed 22574681

Korvald H, Falnes PØ, Laerdahl JK, Bjørås M, Alseth I (2012)
The Schizosaccharomyces pombe AlkB homolog Abh1 exhibits AP lyase activity but no demethylase activity
DNA Repair (Amst), 11 (5), 453-62
DOI 10.1016/j.dnarep.2012.01.014, PubMed 22365419

Lindell K, Fahlgren A, Hjerde E, Willassen NP, Fällman M, Milton DL (2012)
Lipopolysaccharide O-antigen prevents phagocytosis of Vibrio anguillarum by rainbow trout (Oncorhynchus mykiss) skin epithelial cells
PLoS One, 7 (5), e37678
DOI 10.1371/journal.pone.0037678, PubMed 22662189

Pietrzyk JJ, Kwinta P, Bik-Multanowski M, Madetko-Talowska A, Jagła M, Tomasik T, Mitkowska Z, Wollen EJ, Nygård S, Saugstad OD (2012)
New insight into the pathogenesis of retinopathy of prematurity: assessment of whole-genome expression
Pediatr Res, 73 (4 Pt 1), 476-83
DOI 10.1038/pr.2012.195, PubMed 23269122

Rutkovskiy A, Mariero LH, Nygård S, Stensløkken KO, Valen G, Vaage J (2012)
Transient hyperosmolality modulates expression of cardiac aquaporins
Biochem Biophys Res Commun, 425 (1), 70-5
DOI 10.1016/j.bbrc.2012.07.052, PubMed 22820194

Røsjø H, Nygård S, Kaukonen KM, Karlsson S, Stridsberg M, Ruokonen E, Pettilä V, Omland T, FINNSEPSIS Study Group (2012)
Prognostic value of chromogranin A in severe sepsis: data from the FINNSEPSIS study
Intensive Care Med, 38 (5), 820-9
DOI 10.1007/s00134-012-2546-8, PubMed 22491939

Røsjø H, Tamm NN, Kravdal G, Seferian KR, Høiseth AD, Nygård S, Badr P, Røysland R, Omland T (2012)
Diagnostic utility of a single-epitope sandwich B-type natriuretic peptide assay in stable coronary artery disease: data from the Akershus Cardiac Examination (ACE) 1 Study
Clin Biochem, 45 (16-17), 1269-75
DOI 10.1016/j.clinbiochem.2012.05.010, PubMed 22609895

Røysland R, Kravdal G, Høiseth AD, Nygård S, Badr P, Hagve TA, Omland T, Røsjø H (2012)
Cardiac troponin T levels and exercise stress testing in patients with suspected coronary artery disease: the Akershus Cardiac Examination (ACE) 1 study
Clin Sci (Lond), 122 (12), 599-606
DOI 10.1042/CS20110557, PubMed 22239123

Skrbic B, Bjørnstad JL, Marstein HS, Carlson CR, Sjaastad I, Nygård S, Bjørnstad S, Christensen G, Tønnessen T (2012)
Differential regulation of extracellular matrix constituents in myocardial remodeling with and without heart failure following pressure overload
Matrix Biol, 32 (2), 133-42
DOI 10.1016/j.matbio.2012.11.011, PubMed 23220517

Søberg K, Larsen AC, Diskar M, Backe PH, Bjørås M, Jahnsen T, Laerdahl JK, Rognes T, Herberg FW, Skålhegg BS (2012)
Identification and characterization of novel mutations in the human gene encoding the catalytic subunit Calpha of protein kinase A (PKA)
PLoS One, 7 (4), e34838
DOI 10.1371/journal.pone.0034838, PubMed 22514673

Waehre A, Vistnes M, Sjaastad I, Nygård S, Husberg C, Lunde IG, Aukrust P, Yndestad A, Vinge LE, Behmen D, Neukamm C, Brun H, Thaulow E, Christensen G (2012)
Chemokines regulate small leucine-rich proteoglycans in the extracellular matrix of the pressure-overloaded right ventricle
J Appl Physiol (1985), 112 (8), 1372-82
DOI 10.1152/japplphysiol.01350.2011, PubMed 22345433

Zegeye ED, Balasingham SV, Laerdahl JK, Homberset H, Tønjum T (2012)
Mycobacterium tuberculosis RecG binds and unwinds model DNA substrates with a preference for Holliday junctions
Microbiology, 158 (Pt 8), 1982-93
DOI 10.1099/mic.0.058693-0, PubMed 22628485

Publications 2011

Finsen AV, Lunde IG, Sjaastad I, Østli EK, Lyngra M, Jarstadmarken HO, Hasic A, Nygård S, Wilcox-Adelman SA, Goetinck PF, Lyberg T, Skrbic B, Florholmen G, Tønnessen T, Louch WE, Djurovic S, Carlson CR, Christensen G (2011)
Syndecan-4 is essential for development of concentric myocardial hypertrophy via stretch-induced activation of the calcineurin-NFAT pathway
PLoS One, 6 (12), e28302
DOI 10.1371/journal.pone.0028302, PubMed 22164265

Holla ØL, Cameron J, Tveten K, Strøm TB, Berge KE, Laerdahl JK, Leren TP (2011)
Role of the C-terminal domain of PCSK9 in degradation of the LDL receptors
J Lipid Res, 52 (10), 1787-94
DOI 10.1194/jlr.M018093, PubMed 21771976

Kotlar HK, Lewin A, Johansen J, Throne-Holst M, Haverkamp T, Markussen S, Winnberg A, Ringrose P, Aakvik T, Ryeng E, Jakobsen K, Drabløs F, Valla S (2011)
High coverage sequencing of DNA from microorganisms living in an oil reservoir 2.5 kilometres subsurface
Environ Microbiol Rep, 3 (6), 674-81
DOI 10.1111/j.1758-2229.2011.00279.x, PubMed 23761356

Sandve GK, Ferkingstad E, Nygård S (2011)
Sequential Monte Carlo multiple testing
Bioinformatics, 27 (23), 3235-41
DOI 10.1093/bioinformatics/btr568, PubMed 21998154

Star B, Nederbragt AJ, Jentoft S, Grimholt U, Malmstrøm M, Gregers TF, Rounge TB, Paulsen J, Solbakken MH, Sharma A, Wetten OF, Lanzén A, Winer R, Knight J, Vogel JH, Aken B, Andersen O, Lagesen K, Tooming-Klunderud A, Edvardsen RB, Tina KG, Espelund M, Nepal C, Previti C, Karlsen BO et al. (2011)
The genome sequence of Atlantic cod reveals a unique immune system
Nature, 477 (7363), 207-10
DOI 10.1038/nature10342, PubMed 21832995

Sztromwasser P, Puntervoll P, Petersen K (2011)
Data partitioning enables the use of standard SOAP Web Services in genome-scale workflows
J Integr Bioinform, 8 (2), 163
DOI 10.2390/biecoll-jib-2011-163, PubMed 21788681

Tveten K, Holla ØL, Cameron J, Strøm TB, Berge KE, Laerdahl JK, Leren TP (2011)
Interaction between the ligand-binding domain of the LDL receptor and the C-terminal domain of PCSK9 is required for PCSK9 to remain bound to the LDL receptor during endosomal acidification
Hum Mol Genet, 21 (6), 1402-9
DOI 10.1093/hmg/ddr578, PubMed 22156580

Waehre A, Halvorsen B, Yndestad A, Husberg C, Sjaastad I, Nygård S, Dahl CP, Ahmed MS, Finsen AV, Reims H, Louch WE, Hilfiker-Kleiner D, Vinge LE, Roald B, Attramadal H, Lipp M, Gullestad L, Aukrust P, Christensen G (2011)
Lack of chemokine signaling through CXCR5 causes increased mortality, ventricular dilatation and deranged matrix during cardiac pressure overload
PLoS One, 6 (4), e18668
DOI 10.1371/journal.pone.0018668, PubMed 21533157

Weber B, Lindell K, El Qaidi S, Hjerde E, Willassen NP, Milton DL (2011)
The phosphotransferase VanU represses expression of four qrr genes antagonizing VanO-mediated quorum-sensing regulation in Vibrio anguillarum
Microbiology, 157 (Pt 12), 3324-39
DOI 10.1099/mic.0.051011-0, PubMed 21948044

Publications 2010

Bratlie MS, Johansen J, Drabløs F (2010)
Relationship between operon preference and functional properties of persistent genes in bacterial genomes
BMC Genomics, 11, 71
DOI 10.1186/1471-2164-11-71, PubMed 20109203

Bratlie MS, Johansen J, Sherman BT, Huang da W, Lempicki RA, Drabløs F (2010)
Gene duplications in prokaryotes can be associated with environmental adaptation
BMC Genomics, 11, 588
DOI 10.1186/1471-2164-11-588, PubMed 20961426

Hougen K, Aronsen JM, Stokke MK, Enger U, Nygard S, Andersson KB, Christensen G, Sejersted OM, Sjaastad I (2010)
Cre-loxP DNA recombination is possible with only minimal unspecific transcriptional changes and without cardiomyopathy in Tg(alphaMHC-MerCreMer) mice
Am J Physiol Heart Circ Physiol, 299 (5), H1671-8
DOI 10.1152/ajpheart.01155.2009, PubMed 20802136

Publications 2009

Bjerner J, Theodorsson E, Hovig E, Kallner A (2009)
Non-parametric estimation of reference intervals in small non-Gaussian sample sets
Accredit. Qual. Assur., 14 (4), 185-192

Trösse C, Waagbø R, Breck O, Stavrum AK, Petersen K, Olsvik PA (2009)
Genome-wide transcription analysis of histidine-related cataract in Atlantic salmon (Salmo salar L)
Mol Vis, 15, 1332-50
PubMed 19597568

van Beijnum JR, Petersen K, Griffioen AW (2009)
Tumor endothelium is characterized by a matrix remodeling signature
Front Biosci (Schol Ed), 1, 216-25
PubMed 19482697

Publications 2008

Klepper K, Sandve GK, Abul O, Johansen J, Drablos F (2008)
Assessment of composite motif discovery methods
BMC Bioinformatics, 9, 123
DOI 10.1186/1471-2105-9-123, PubMed 18302777

Olsvik PA, Lie KK, Mykkeltvedt E, Samuelsen OB, Petersen K, Stavrum AK, Lunestad BT (2008)
Pharmacokinetics and transcriptional effects of the anti-salmon lice drug emamectin benzoate in Atlantic salmon (Salmo salar L.)
BMC Pharmacol, 8, 16
DOI 10.1186/1471-2210-8-16, PubMed 18786259

Stavrum AK, Petersen K, Jonassen I, Dysvik B (2008)
Analysis of gene-expression data using J-Express
Curr Protoc Bioinformatics, Chapter 7, Unit 7.3
DOI 10.1002/0471250953.bi0703s21, PubMed 18428687