Publications 2023

Bargheet A, Klingenberg C, Esaiassen E, Hjerde E, Cavanagh JP, Bengtsson-Palme J, Pettersen VK (2023)
Development of early life gut resistome and mobilome across gestational ages and microbiota-modifying treatments
EBioMedicine, 92, 104613
DOI 10.1016/j.ebiom.2023.104613, PubMed 37187112

Kumar A, Robertsen EM, Willassen NP, Fu J, Hjerde E (2023)
Comparative analysis of HiSeq3000 and BGISEQ-500 sequencing platform over whole genome sequencing metagenomics data
Genomics Inform, 21 (4), e49
DOI 10.5808/gi.23072, PubMed 38224716

Namløs HM, Khelik K, Nakken S, Vodák D, Hovig E, Myklebost O, Boye K, Meza-Zepeda LA (2023)
Chromosomal instability and a deregulated cell cycle are intrinsic features of high-risk gastrointestinal stromal tumours with a metastatic potential
Mol Oncol, 17 (11), 2432-2450
DOI 10.1002/1878-0261.13514, PubMed 37622176

Neves A, Cuesta I, Hjerde E, Klemetsen T, Salgado D, van Helden J, Rahman N, Fatima N, Karathanasis N, Zmora P, Åkerström WN, Grellscheid SN, Waheed Z, Blomberg N (2023)
FAIR+E pathogen data for surveillance and research: lessons from COVID-19
Front Public Health, 11, 1289945
DOI 10.3389/fpubh.2023.1289945, PubMed 38074768

Schiavi A, Salveridou E, Brinkmann V, Shaik A, Menzel R, Kalyanasundaram S, Nygård S, Nilsen H, Ventura N (2023)
Mitochondria hormesis delays aging and associated diseases in Caenorhabditis elegans impacting on key ferroptosis players
iScience, 26 (4), 106448
DOI 10.1016/j.isci.2023.106448, PubMed 37020951

Strøm TB, Asprusten E, Laerdahl JK, Øygard I, Hussain MM, Bogsrud MP, Leren TP (2023)
Missense mutation Q384K in the APOB gene affecting the large lipid transfer module of apoB reduces the secretion of apoB-100 in the liver without reducing the secretion of apoB-48 in the intestine
J Clin Lipidol, 17 (6), 800-807
DOI 10.1016/j.jacl.2023.08.009, PubMed 37718180

Verleih M, Visnovska T, Nguinkal JA, Rebl A, Goldammer T, Andreassen R (2023)
The Discovery and Characterization of Conserved and Novel miRNAs in the Different Developmental Stages and Organs of Pikeperch (Sander lucioperca)
Int J Mol Sci, 25 (1)
DOI 10.3390/ijms25010189, PubMed 38203361

Ølnes ÅS, Teigen M, Laerdahl JK, Leren TP, Strøm TB, Bjune K (2023)
Variants in the CETP gene affect levels of HDL cholesterol by reducing the amount, and not the specific lipid transfer activity, of secreted CETP
PLoS One, 18 (12), e0294764
DOI 10.1371/journal.pone.0294764, PubMed 38039300

Publications 2022

Chakraborty S, Woldemariam NT, Visnovska T, Rise ML, Boyce D, Santander J, Andreassen R (2022)
Characterization of miRNAs in Embryonic, Larval, and Adult Lumpfish Provides a Reference miRNAome for Cyclopterus lumpus
Biology (Basel), 11 (1)
DOI 10.3390/biology11010130, PubMed 35053128

Fromm B, Høye E, Domanska D, Zhong X, Aparicio-Puerta E, Ovchinnikov V, Umu SU, Chabot PJ, Kang W, Aslanzadeh M, Tarbier M, Mármol-Sánchez E, Urgese G, Johansen M, Hovig E, Hackenberg M, Friedländer MR, Peterson KJ (2022)
MirGeneDB 2.1: toward a complete sampling of all major animal phyla
Nucleic Acids Res, 50 (D1), D204-D210
DOI 10.1093/nar/gkab1101, PubMed 34850127

Lindstedt K, Buczek D, Pedersen T, Hjerde E, Raffelsberger N, Suzuki Y, Brisse S, Holt K, Samuelsen Ø, Sundsfjord A (2022)
Detection of Klebsiella pneumoniae human gut carriage: a comparison of culture, qPCR, and whole metagenomic sequencing methods
Gut Microbes, 14 (1), 2118500
DOI 10.1080/19490976.2022.2118500, PubMed 36045603

Maharajan AD, Hjerde E, Hansen H, Willassen NP (2022)
Quorum Sensing Controls the CRISPR and Type VI Secretion Systems in Aliivibrio wodanis 06/09/139
Front Vet Sci, 9, 799414
DOI 10.3389/fvets.2022.799414, PubMed 35211539

Przybyła W, Gjersvoll Paulsen KM, Mishra CK, Nygård S, Engebretsen S, Ruud E, Trøen G, Beiske K, Baumbusch LO (2022)
Whole exome sequencing of high-risk neuroblastoma identifies novel non-synonymous variants
PLoS One, 17 (8), e0273280
DOI 10.1371/journal.pone.0273280, PubMed 36037157

Shwe A, Krasnov A, Visnovska T, Ramberg S, Østbye TK, Andreassen R (2022)
Expression Analysis in Atlantic Salmon Liver Reveals miRNAs Associated with Smoltification and Seawater Adaptation
Biology (Basel), 11 (5)
DOI 10.3390/biology11050688, PubMed 35625416

Shwe A, Krasnov A, Visnovska T, Ramberg S, Østbye TK, Andreassen R (2022)
Differential Expression of miRNAs and Their Predicted Target Genes Indicates That Gene Expression in Atlantic Salmon Gill Is Post-Transcriptionally Regulated by miRNAs in the Parr-Smolt Transformation and Adaptation to Sea Water
Int J Mol Sci, 23 (15)
DOI 10.3390/ijms23158831, PubMed 35955964

Zavaleta E, Solis N, Palacios MI, Zevallos-Escobar LE, Corales EV, Bazo-Alvarez JC, Dominguez-Barrera C, Campos A, Wernhoff P, Ekstrøm PO, Møller P, Visnovska T, Hovig E, Balazar-Palacios J, Alvarez-Valenzuela K, Nakken S, Dominguez-Valentin M (2022)
Genetic Characterization in High-Risk Individuals from a Low-Resource City of Peru
Cancers (Basel), 14 (22)
DOI 10.3390/cancers14225603, PubMed 36428697

Publications 2021

Ferreira FA, Helmersen K, Visnovska T, Jørgensen SB, Aamot HV (2021)
Rapid nanopore-based DNA sequencing protocol of antibiotic-resistant bacteria for use in surveillance and outbreak investigation
Microb Genom, 7 (4)
DOI 10.1099/mgen.0.000557, PubMed 33885360

Jiang X, Bergquist A, Löscher BS, Venkatesh G, Mold JE, Holm K, Laerdahl JK, Skånland SS, Maleki KT, Cornillet M, Taskén K, Franke A, Karlsen TH, Björkström NK, Melum E (2021)
A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis
Sci Transl Med, 13 (582)
DOI 10.1126/scitranslmed.abb0036, PubMed 33627483

Lunde TM, Hjerde E, Al-Haroni M (2021)
Prevalence, diversity and transferability of the Tn916-Tn1545 family ICE in oral streptococci
J Oral Microbiol, 13 (1), 1896874
DOI 10.1080/20002297.2021.1896874, PubMed 33796228

Mygland L, Brinch SA, Strand MF, Olsen PA, Aizenshtadt A, Lund K, Solberg NT, Lycke M, Thorvaldsen TE, Espada S, Misaghian D, Page CM, Agafonov O, Nygård S, Chi NW, Lin E, Tan J, Yu Y, Costa M, Krauss S, Waaler J (2021)
Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines
iScience, 24 (7), 102807
DOI 10.1016/j.isci.2021.102807, PubMed 34337362

Quiles-Jiménez A, Gregersen I, Segers FM, Skarpengland T, Kroustallaki P, Yang K, Kong XY, Lauritzen KH, Olsen MB, Karlsen TR, Nyman TA, Sagen EL, Bjerkeli V, Suganthan R, Nygård S, Scheffler K, Prins J, Van der Veer E, Øgaard JD, Fløisand Y, Jørgensen HF, Holven KB, Biessen EA, Nilsen H, Dahl TB et al. (2021)
DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development
Atherosclerosis, 324, 123-132
DOI 10.1016/j.atherosclerosis.2021.02.023, PubMed 33714552

Ramberg H, Richardsen E, de Souza GA, Rakaee M, Stensland ME, Braadland PR, Nygård S, Ögren O, Guldvik IJ, Berge V, Svindland A, Taskén KA, Andersen S (2021)
Proteomic analyses identify major vault protein as a prognostic biomarker for fatal prostate cancer
Carcinogenesis, 42 (5), 685-693
DOI 10.1093/carcin/bgab015, PubMed 33609362

Roliński M, Montaldo NP, Aksu ME, Fordyce Martin SL, Brambilla A, Kunath N, Johansen J, Erlandsen SE, Liabbak NB, Rian K, Bjørås M, Sætrom P, van Loon B (2021)
Loss of Mediator complex subunit 13 (MED13) promotes resistance to alkylation through cyclin D1 upregulation
Nucleic Acids Res, 49 (3), 1470-1484
DOI 10.1093/nar/gkaa1289, PubMed 33444446

Sanabria AM, Janice J, Hjerde E, Simonsen GS, Hanssen AM (2021)
Shotgun-metagenomics based prediction of antibiotic resistance and virulence determinants in Staphylococcus aureus from periprosthetic tissue on blood culture bottles
Sci Rep, 11 (1), 20848
DOI 10.1038/s41598-021-00383-7, PubMed 34675288

Publications 2020

Backe PH, Laerdahl JK, Kittelsen LS, Dalhus B, Mørkrid L, Bjørås M (2020)
Structural basis for substrate and product recognition in human phosphoglucomutase-1 (PGM1) isoform 2, a member of the α-D-phosphohexomutase superfamily
Sci Rep, 10 (1), 5656
DOI 10.1038/s41598-020-62548-0, PubMed 32221390

Ferrante L, Opdal SH, Nygård S, Vege Å, Rognum TO (2020)
Gene expression profile in cases of infectious death in infancy
Pediatr Res, 89 (3), 483-487
DOI 10.1038/s41390-020-0896-4, PubMed 32299088

Ferrante L, Opdal SH, Nygaard V (2020)
No association to sudden infant death syndrome detected by targeted amplicon sequencing of 24 genes
Acta Paediatr, 109 (12), 2636-2640
DOI 10.1111/apa.15295, PubMed 32271962

Flygel TT, Sovershaeva E, Claassen-Weitz S, Hjerde E, Mwaikono KS, Odland JØ, Ferrand RA, Mchugh G, Gutteberg TJ, Nicol MP, Cavanagh JP, Flægstad T, BREATHE Study Team (2020)
Composition of Gut Microbiota of Children and Adolescents With Perinatal Human Immunodeficiency Virus Infection Taking Antiretroviral Therapy in Zimbabwe
J Infect Dis, 221 (3), 483-492
DOI 10.1093/infdis/jiz473, PubMed 31549151

Goll R, Johnsen PH, Hjerde E, Diab J, Valle PC, Hilpusch F, Cavanagh JP (2020)
Effects of fecal microbiota transplantation in subjects with irritable bowel syndrome are mirrored by changes in gut microbiome
Gut Microbes, 12 (1), 1794263
DOI 10.1080/19490976.2020.1794263, PubMed 32991818

Ree AH, Nygaard V, Boye K, Heinrich D, Dueland S, Bergheim IR, Johansen C, Beiske K, Negård A, Lund-Iversen M, Nygaard V, Hovig E, Nakken S, Nasser S, Julsrud L, Reisse CH, Ruud EA, Kristensen VN, Flørenes VA, Geitvik GA, Lingjærde OC, Børresen-Dale AL, Russnes HG, Mælandsmo GM, Flatmark K (2020)
Molecularly matched therapy in the context of sensitivity, resistance, and safety; patient outcomes in end-stage cancer - the MetAction study
Acta Oncol, 59 (7), 733-740
DOI 10.1080/0284186X.2020.1742377, PubMed 32208873

Sanabria A, Hjerde E, Johannessen M, Sollid JE, Simonsen GS, Hanssen AM (2020)
Shotgun-Metagenomics on Positive Blood Culture Bottles Inoculated With Prosthetic Joint Tissue: A Proof of Concept Study
Front Microbiol, 11, 1687
DOI 10.3389/fmicb.2020.01687, PubMed 32765476

Woldemariam NT, Agafonov O, Sindre H, Høyheim B, Houston RD, Robledo D, Bron JE, Andreassen R (2020)
miRNAs Predicted to Regulate Host Anti-viral Gene Pathways in IPNV-Challenged Atlantic Salmon Fry Are Affected by Viral Load, and Associated With the Major IPN Resistance QTL Genotypes in Late Infection
Front Immunol, 11, 2113
DOI 10.3389/fimmu.2020.02113, PubMed 33013890

Publications 2019

Brynildsen J, Petäjä L, Myhre PL, Lyngbakken MN, Nygård S, Stridsberg M, Christensen G, Ottesen AH, Pettilä V, Omland T, Røsjø H (2019)
Circulating Secretoneurin Concentrations After Cardiac Surgery: Data From the FINNish Acute Kidney Injury Heart Study
Crit Care Med, 47 (5), e412-e419
DOI 10.1097/CCM.0000000000003670, PubMed 30730440

Flørenes VA, Flem-Karlsen K, McFadden E, Bergheim IR, Nygaard V, Nygård V, Farstad IN, Øy GF, Emilsen E, Giller-Fleten K, Ree AH, Flatmark K, Gullestad HP, Hermann R, Ryder T, Wernhoff P, Mælandsmo GM (2019)
A Three-dimensional Ex Vivo Viability Assay Reveals a Strong Correlation Between Response to Targeted Inhibitors and Mutation Status in Melanoma Lymph Node Metastases
Transl Oncol, 12 (7), 951-958
DOI 10.1016/j.tranon.2019.04.001, PubMed 31096111

Forthun RB, Hovland R, Schuster C, Puntervoll H, Brodal HP, Namløs HM, Aasheim LB, Meza-Zepeda LA, Gjertsen BT, Knappskog S, Straume O (2019)
ctDNA detected by ddPCR reveals changes in tumour load in metastatic malignant melanoma treated with bevacizumab
Sci Rep, 9 (1), 17471
DOI 10.1038/s41598-019-53917-5, PubMed 31767937

Hagberg G, Fure B, Thommessen B, Ihle-Hansen H, Øksengård AR, Nygård S, Pendlebury ST, Beyer MK, Wyller TB, Ihle-Hansen H (2019)
Predictors for Favorable Cognitive Outcome Post-Stroke: A-Seven-Year Follow-Up Study
Dement Geriatr Cogn Disord, 48 (1-2), 45-55
DOI 10.1159/000501850, PubMed 31461703

Ihle-Hansen H, Vigen T, Berge T, Hagberg G, Engedal K, Rønning OM, Thommessen B, Lyngbakken MN, Nygård S, Røsjø H, Tveit A, Ihle-Hansen H (2019)
Carotid Atherosclerosis and Cognitive Function in a General Population Aged 63-65 Years: Data from the Akershus Cardiac Examination (ACE) 1950 Study
J Alzheimers Dis, 70 (4), 1041-1049
DOI 10.3233/JAD-190327, PubMed 31306128

Kanduri C, Bock C, Gundersen S, Hovig E, Sandve GK (2019)
Colocalization analyses of genomic elements: approaches, recommendations and challenges
Bioinformatics, 35 (9), 1615-1624
DOI 10.1093/bioinformatics/bty835, PubMed 30307532

Khider M, Hjerde E, Hansen H, Willassen NP (2019)
Differential expression profiling of ΔlitR and ΔrpoQ mutants reveals insight into QS regulation of motility, adhesion and biofilm formation in Aliivibrio salmonicida
BMC Genomics, 20 (1), 220
DOI 10.1186/s12864-019-5594-4, PubMed 30876404

Le Doujet T, De Santi C, Klemetsen T, Hjerde E, Willassen NP, Haugen P (2019)
Closely-related Photobacterium strains comprise the majority of bacteria in the gut of migrating Atlantic cod (Gadus morhua)
Microbiome, 7 (1), 64
DOI 10.1186/s40168-019-0681-y, PubMed 30995938

Lie-Jensen A, Ivanauskiene K, Malerød L, Jain A, Tan KW, Laerdahl JK, Liestøl K, Stenmark H, Haglund K (2019)
Centralspindlin Recruits ALIX to the Midbody during Cytokinetic Abscission in Drosophila via a Mechanism Analogous to Virus Budding
Curr Biol, 29 (20), 3538-3548.e7
DOI 10.1016/j.cub.2019.09.025, PubMed 31607533

Lund-Andersen C, Nakken S, Nygård S, Fromm B, Aasheim LB, Davidson B, Julsrud L, Abrahamsen TW, Kristensen AT, Dybdahl B, Larsen SG, Hovig E, Flatmark K (2019)
Integrative genomic analysis of peritoneal malignant mesothelioma: understanding a case with extraordinary chemotherapy response
Cold Spring Harb Mol Case Stud, 5 (2)
DOI 10.1101/mcs.a003566, PubMed 30862609

Malt EA, Juhasz K, Frengen A, Wangensteen T, Emilsen NM, Hansen B, Agafonov O, Nilsen HL (2019)
Neuropsychiatric phenotype in relation to gene variants in the hemizygous allele in 3q29 deletion carriers: A case series
Mol Genet Genomic Med, 7 (9), e889
DOI 10.1002/mgg3.889, PubMed 31347308

Mohammadzadeh N, Lunde IG, Andenæs K, Strand ME, Aronsen JM, Skrbic B, Marstein HS, Bandlien C, Nygård S, Gorham J, Sjaastad I, Chakravarti S, Christensen G, Engebretsen KVT, Tønnessen T (2019)
The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload
Sci Rep, 9 (1), 9206
DOI 10.1038/s41598-019-45651-9, PubMed 31235849

Nygård S, Lingjærde OC, Caldas C, Hovig E, Børresen-Dale AL, Helland Å, Haakensen VD (2019)
PathTracer: High-sensitivity detection of differential pathway activity in tumours
Sci Rep, 9 (1), 16332
DOI 10.1038/s41598-019-52529-3, PubMed 31704995

Ree AH, Nygaard V, Russnes HG, Heinrich D, Nygaard V, Johansen C, Bergheim IR, Hovig E, Beiske K, Negård A, Børresen-Dale AL, Flatmark K, Mælandsmo GM (2019)
Responsiveness to PD-1 Blockade in End-Stage Colon Cancer with Gene Locus 9p24.1 Copy-Number Gain
Cancer Immunol Res, 7 (5), 701-706
DOI 10.1158/2326-6066.CIR-18-0777, PubMed 30804006

Strøm TB, Vinje T, Bjune K, da Costa LT, Laerdahl JK, Leren TP (2019)
Lysosomal acid lipase does not have a propeptide and should not be considered being a proprotein
Proteins, 88 (3), 440-448
DOI 10.1002/prot.25821, PubMed 31587363

Söderberg JJ, Grgic M, Hjerde E, Haugen P (2019)
Aliivibrio wodanis as a production host: development of genetic tools for expression of cold-active enzymes
Microb Cell Fact, 18 (1), 197
DOI 10.1186/s12934-019-1247-1, PubMed 31711487

Vinje T, Laerdahl JK, Bjune K, Leren TP, Strøm TB (2019)
Characterization of the mechanisms by which missense mutations in the lysosomal acid lipase gene disrupt enzymatic activity
Hum Mol Genet, 28 (18), 3043-3052
DOI 10.1093/hmg/ddz114, PubMed 31131398

Visnovska T, Biggs PJ, Schmeier S, Frizelle FA, Purcell RV (2019)
Metagenomics and transcriptomics data from human colorectal cancer
Sci Data, 6 (1), 116
DOI 10.1038/s41597-019-0117-3, PubMed 31278253

Woldemariam NT, Agafonov O, Høyheim B, Houston RD, Taggart JB, Andreassen R (2019)
Expanding the miRNA Repertoire in Atlantic Salmon; Discovery of IsomiRs and miRNAs Highly Expressed in Different Tissues and Developmental Stages
Cells, 8 (1)
DOI 10.3390/cells8010042, PubMed 30641951

Xavier A, Olsen MF, Lavik LA, Johansen J, Singh AK, Sjursen W, Scott RJ, Talseth-Palmer BA (2019)
Comprehensive mismatch repair gene panel identifies variants in patients with Lynch-like syndrome
Mol Genet Genomic Med, 7 (8), e850
DOI 10.1002/mgg3.850, PubMed 31297992

Publications 2018

Aqrawi LA, Jensen JL, Øijordsbakken G, Ruus AK, Nygård S, Holden M, Jonsson R, Galtung HK, Skarstein K (2018)
Signalling pathways identified in salivary glands from primary Sjögren's syndrome patients reveal enhanced adipose tissue development
Autoimmunity, 51 (3), 135-146
DOI 10.1080/08916934.2018.1446525, PubMed 29504848

Brynildsen J, Petäjä L, Pettilä V, Nygård S, Vaara ST, Linko R, Okkonen M, Hagve TA, Soininen L, Suojaranta-Ylinen R, Lyngbakken MN, Omland T, Røsjø H (2018)
The predictive value of NT-proBNP and hs-TnT for risk of death in cardiac surgical patients
Clin Biochem, 53, 65-71
DOI 10.1016/j.clinbiochem.2018.01.012, PubMed 29371002

Braadland PR, Giskeødegård G, Sandsmark E, Bertilsson H, Euceda LR, Hansen AF, Guldvik IJ, Selnæs KM, Grytli HH, Katz B, Svindland A, Bathen TF, Eri LM, Nygård S, Berge V, Taskén KA, Tessem MB (2018)
Ex vivo metabolic fingerprinting identifies biomarkers predictive of prostate cancer recurrence following radical prostatectomy
Br J Cancer, 118 (6), e11
DOI 10.1038/bjc.2017.470, PubMed 29462127

Dominguez Del Angel V, Hjerde E, Sterck L, Capella-Gutierrez S, Notredame C, Vinnere Pettersson O, Amselem J, Bouri L, Bocs S, Klopp C, Gibrat JF, Vlasova A, Leskosek BL, Soler L, Binzer-Panchal M, Lantz H (2018)
Ten steps to get started in Genome Assembly and Annotation
F1000Res, 7
DOI 10.12688/f1000research.13598.1, PubMed 29568489

Esaiassen E, Hjerde E, Cavanagh JP, Pedersen T, Andresen JH, Rettedal SI, Støen R, Nakstad B, Willassen NP, Klingenberg C (2018)
Effects of Probiotic Supplementation on the Gut Microbiota and Antibiotic Resistome Development in Preterm Infants
Front Pediatr, 6, 347
DOI 10.3389/fped.2018.00347, PubMed 30505830

Ihle-Hansen H, Vigen T, Ihle-Hansen H, Rønning OM, Berge T, Thommessen B, Lyngbakken MN, Orstad EB, Enger S, Nygård S, Røsjø H, Tveit A (2018)
Prevalence of Carotid Plaque in a 63- to 65-Year-Old Norwegian Cohort From the General Population: The ACE (Akershus Cardiac Examination) 1950 Study
J Am Heart Assoc, 7 (10)
DOI 10.1161/JAHA.118.008562, PubMed 29739796

Simovski B, Kanduri C, Gundersen S, Titov D, Domanska D, Bock C, Bossini-Castillo L, Chikina M, Favorov A, Layer RM, Mironov AA, Quinlan AR, Sheffield NC, Trynka G, Sandve GK (2018)
Coloc-stats: a unified web interface to perform colocalization analysis of genomic features
Nucleic Acids Res, 46 (W1), W186-W193
DOI 10.1093/nar/gky474, PubMed 29873782

Tekle KM, Gundersen S, Klepper K, Bongo LA, Raknes IA, Li X, Zhang W, Andreetta C, Mulugeta TD, Kalaš M, Rye MB, Hjerde E, Antony Samy JK, Fornous G, Azab A, Våge DI, Hovig E, Willassen NP, Drabløs F, Nygård S, Petersen K, Jonassen I (2018)
Norwegian e-Infrastructure for Life Sciences (NeLS)
F1000Res, 7
DOI 10.12688/f1000research.15119.1, PubMed 30271575

Tunsjø HS, Kalyanasundaram S, Charnock C, Leegaard TM, Moen AEF (2018)
Challenges in the identification of methicillin-resistant Staphylococcus argenteus by routine diagnostics
APMIS, 126 (6), 533-537
DOI 10.1111/apm.12843, PubMed 29924450

Vodák D, Lorenz S, Nakken S, Aasheim LB, Holte H, Bai B, Myklebost O, Meza-Zepeda LA, Hovig E (2018)
Sample-Index Misassignment Impacts Tumour Exome Sequencing
Sci Rep, 8 (1), 5307
DOI 10.1038/s41598-018-23563-4, PubMed 29593270

Publications 2017

Andreassen R, Woldemariam NT, Egeland IØ, Agafonov O, Sindre H, Høyheim B (2017)
Identification of differentially expressed Atlantic salmon miRNAs responding to salmonid alphavirus (SAV) infection
BMC Genomics, 18 (1), 349
DOI 10.1186/s12864-017-3741-3, PubMed 28472924

Braadland PR, Giskeødegård G, Sandsmark E, Bertilsson H, Euceda LR, Hansen AF, Guldvik IJ, Selnæs KM, Grytli HH, Katz B, Svindland A, Bathen TF, Eri LM, Nygård S, Berge V, Taskén KA, Tessem MB (2017)
Ex vivo metabolic fingerprinting identifies biomarkers predictive of prostate cancer recurrence following radical prostatectomy
Br J Cancer, 117 (11), 1656-1664
DOI 10.1038/bjc.2017.346, PubMed 28972967

Casabona MG, Kneuper H, Alferes de Lima D, Harkins CP, Zoltner M, Hjerde E, Holden MTG, Palmer T (2017)
Haem-iron plays a key role in the regulation of the Ess/type VII secretion system of Staphylococcus aureus RN6390
Microbiology (Reading), 163 (12), 1839-1850
DOI 10.1099/mic.0.000579, PubMed 29171824

de Vries EMG, Färkkilä M, Milkiewicz P, Hov JR, Eksteen B, Thorburn D, Chazouillères O, Pares A, Nygård S, Gilja OH, Wunsch E, Invernizzi P, Carbone M, Bernuzzi F, Boberg KM, Røsjø H, Rosenberg W, Beuers UH, Ponsioen CY, Karlsen TH, Vesterhus M (2017)
Enhanced liver fibrosis test predicts transplant-free survival in primary sclerosing cholangitis, a multi-centre study
Liver Int, 37 (10), 1554-1561
DOI 10.1111/liv.13402, PubMed 28267887

Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C, Norwegian Study Group on Invasive Bifidobacterial Infections (2017)
Bifidobacterium Bacteremia: Clinical Characteristics and a Genomic Approach To Assess Pathogenicity
J Clin Microbiol, 55 (7), 2234-2248
DOI 10.1128/JCM.00150-17, PubMed 28490487

Hansen MF, Johansen J, Sylvander AE, Bjørnevoll I, Talseth-Palmer BA, Lavik LAS, Xavier A, Engebretsen LF, Scott RJ, Drabløs F, Sjursen W (2017)
Use of multigene-panel identifies pathogenic variants in several CRC-predisposing genes in patients previously tested for Lynch Syndrome
Clin Genet, 92 (4), 405-414
DOI 10.1111/cge.12994, PubMed 28195393

Karlsen C, Hjerde E, Klemetsen T, Willassen NP (2017)
Pan genome and CRISPR analyses of the bacterial fish pathogen Moritella viscosa
BMC Genomics, 18 (1), 313
DOI 10.1186/s12864-017-3693-7, PubMed 28427330

Landfors M, Johansen J, Aronsen JM, Vågbø CB, Doré LC, He C, Sjaastad I, Sætrom P, Fedorcsák P, Dahl JA, Aanes H, Fußer M, Klungland A (2017)
Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation
Cell Discov, 3, 17013
DOI 10.1038/celldisc.2017.13, PubMed 28529766

Meisal R, Rounge TB, Christiansen IK, Eieland AK, Worren MM, Molden TF, Kommedal Ø, Hovig E, Leegaard TM, Ambur OH (2017)
HPV Genotyping of Modified General Primer-Amplicons Is More Analytically Sensitive and Specific by Sequencing than by Hybridization
PLoS One, 12 (1), e0169074
DOI 10.1371/journal.pone.0169074, PubMed 28045981

Myhre PL, Stridsberg M, Linko R, Okkonen M, Nygård S, Christensen G, Pettilä V, Omland T, Røsjø H, FINNALI Study Group (2017)
Circulating chromogranin B levels in patients with acute respiratory failure: data from the FINNALI Study
Biomarkers, 22 (8), 775-781
DOI 10.1080/1354750X.2016.1269200, PubMed 28049363

Olsen MB, Hildrestrand GA, Scheffler K, Vinge LE, Alfsnes K, Palibrk V, Wang J, Neurauter CG, Luna L, Johansen J, Øgaard JDS, Ohm IK, Slupphaug G, Kuśnierczyk A, Fiane AE, Brorson SH, Zhang L, Gullestad L, Louch WE, Iversen PO, Østlie I, Klungland A, Christensen G, Sjaastad I, Sætrom P et al. (2017)
NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture
Cell Rep, 18 (1), 82-92
DOI 10.1016/j.celrep.2016.12.009, PubMed 28052262

Ree AH, Russnes HG, Heinrich D, Dueland S, Boye K, Nygaard V, Silwal-Pandit L, Østrup O, Hovig E, Nygaard V, Rødland EA, Nakken S, Øien JT, Johansen C, Bergheim IR, Skarpeteig V, Sathermugathevan M, Sauer T, Lund-Iversen M, Beiske K, Nasser S, Julsrud L, Reisse CH, Ruud EA, Flørenes VA et al. (2017)
Implementing precision cancer medicine in the public health services of Norway: the diagnostic infrastructure and a cost estimate
ESMO Open, 2 (2), e000158
DOI 10.1136/esmoopen-2017-000158, PubMed 28761742

Strøm TB, Laerdahl JK, Leren TP (2017)
Mutations affecting the transmembrane domain of the LDL receptor: impact of charged residues on the membrane insertion
Hum Mol Genet, 26 (9), 1634-1642
DOI 10.1093/hmg/ddx068, PubMed 28334946

Søberg K, Moen LV, Skålhegg BS, Laerdahl JK (2017)
Evolution of the cAMP-dependent protein kinase (PKA) catalytic subunit isoforms
PLoS One, 12 (7), e0181091
DOI 10.1371/journal.pone.0181091, PubMed 28742821

Thode SK, Bækkedal C, Söderberg JJ, Hjerde E, Hansen H, Haugen P (2017)
Construction of a fur null mutant and RNA-sequencing provide deeper global understanding of the Aliivibrio salmonicida Fur regulon
PeerJ, 5, e3461
DOI 10.7717/peerj.3461, PubMed 28717590

Vesterhus M, Holm A, Hov JR, Nygård S, Schrumpf E, Melum E, Thorbjørnsen LW, Paulsen V, Lundin K, Dale I, Gilja OH, Zweers SJLB, Vatn M, Schaap FG, Jansen PLM, Ueland T, Røsjø H, Moum B, Ponsioen CY, Boberg KM, Färkkilä M, Karlsen TH, Lund-Johansen F (2017)
Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis
J Hepatol, 66 (6), 1214-1222
DOI 10.1016/j.jhep.2017.01.019, PubMed 28161472

Volchenkov R, Nygaard V, Sener Z, Skålhegg BS (2017)
Th17 Polarization under Hypoxia Results in Increased IL-10 Production in a Pathogen-Independent Manner
Front Immunol, 8, 698
DOI 10.3389/fimmu.2017.00698, PubMed 28674533

Winther JA, Brynildsen J, Høiseth AD, Strand H, Følling I, Christensen G, Nygård S, Røsjø H, Omland T (2017)
Prognostic and diagnostic significance of copeptin in acute exacerbation of chronic obstructive pulmonary disease and acute heart failure: data from the ACE 2 study
Respir Res, 18 (1), 184
DOI 10.1186/s12931-017-0665-z, PubMed 29100503

Publications 2016

Andreassen R, Rangnes F, Sivertsen M, Chiang M, Tran M, Worren MM (2016)
Discovery of miRNAs and Their Corresponding miRNA Genes in Atlantic Cod (Gadus morhua): Use of Stable miRNAs as Reference Genes Reveals Subgroups of miRNAs That Are Highly Expressed in Particular Organs
PLoS One, 11 (4), e0153324
DOI 10.1371/journal.pone.0153324, PubMed 27128807

Esaiassen E, Cavanagh P, Hjerde E, Simonsen GS, Støen R, Klingenberg C (2016)
Bifidobacterium longum Subspecies infantis Bacteremia in 3 Extremely Preterm Infants Receiving Probiotics
Emerg Infect Dis, 22 (9), 1664-6
DOI 10.3201/eid2209.160033, PubMed 27532215

Fang EF, Kassahun H, Croteau DL, Scheibye-Knudsen M, Marosi K, Lu H, Shamanna RA, Kalyanasundaram S, Bollineni RC, Wilson MA, Iser WB, Wollman BN, Morevati M, Li J, Kerr JS, Lu Q, Waltz TB, Tian J, Sinclair DA, Mattson MP, Nilsen H, Bohr VA (2016)
NAD⁺ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair
Cell Metab, 24 (4), 566-581
DOI 10.1016/j.cmet.2016.09.004, PubMed 27732836

Ferrante L, Rognum TO, Vege Å, Nygård S, Opdal SH (2016)
Altered gene expression and possible immunodeficiency in cases of sudden infant death syndrome
Pediatr Res, 80 (1), 77-84
DOI 10.1038/pr.2016.45, PubMed 26959483

Kummen M, Holm K, Anmarkrud JA, Nygård S, Vesterhus M, Høivik ML, Trøseid M, Marschall HU, Schrumpf E, Moum B, Røsjø H, Aukrust P, Karlsen TH, Hov JR (2016)
The gut microbial profile in patients with primary sclerosing cholangitis is distinct from patients with ulcerative colitis without biliary disease and healthy controls
Gut, 66 (4), 611-619
DOI 10.1136/gutjnl-2015-310500, PubMed 26887816

Lyngbakken MN, Røsjø H, Holmen OL, Nygård S, Dalen H, Hveem K, Omland T (2016)
Gender, High-Sensitivity Troponin I, and the Risk of Cardiovascular Events (from the Nord-Trøndelag Health Study)
Am J Cardiol, 118 (6), 816-821
DOI 10.1016/j.amjcard.2016.06.043, PubMed 27453509

Lyngbakken MN, Skranes JB, de Lemos JA, Nygård S, Dalen H, Hveem K, Røsjø H, Omland T (2016)
Impact of Smoking on Circulating Cardiac Troponin I Concentrations and Cardiovascular Events in the General Population: The HUNT Study (Nord-Trøndelag Health Study)
Circulation, 134 (24), 1962-1972
DOI 10.1161/CIRCULATIONAHA.116.023726, PubMed 27815376

Moen MN, Fjær R, Hamdani EH, Laerdahl JK, Menchini RJ, Vigeland MD, Sheng Y, Undlien DE, Hassel B, Salih MA, El Khashab HY, Selmer KK, Chaudhry FA (2016)
Pathogenic variants in KCTD7 perturb neuronal K+ fluxes and glutamine transport
Brain, 139 (Pt 12), 3109-3120
DOI 10.1093/brain/aww244, PubMed 27742667

Munkley J, Vodak D, Livermore KE, James K, Wilson BT, Knight B, Mccullagh P, Mcgrath J, Crundwell M, Harries LW, Leung HY, Robson CN, Mills IG, Rajan P, Elliott DJ (2016)
Glycosylation is an Androgen-Regulated Process Essential for Prostate Cancer Cell Viability
EBioMedicine, 8, 103-116
DOI 10.1016/j.ebiom.2016.04.018, PubMed 27428423

Myhre PL, Ottesen AH, Okkonen M, Linko R, Stridsberg M, Nygård S, Christensen G, Pettilä V, Omland T, Røsjø H, FINNALI Laboratory Study Group (2016)
Prognostic Value of Secretoneurin in Patients with Acute Respiratory Failure: Data from the FINNALI Study
Clin Chem, 62 (10), 1380-9
DOI 10.1373/clinchem.2016.258764, PubMed 27540029

Røsjø H, Stridsberg M, Ottesen AH, Nygård S, Christensen G, Pettilä V, Linko R, Karlsson S, Varpula T, Ruokonen E, Omland T, FINNSEPSIS and FINNALI Study Groups (2016)
Prognostic Value of Secretoneurin in Critically Ill Patients With Infections
Crit Care Med, 44 (10), 1882-90
DOI 10.1097/CCM.0000000000001832, PubMed 27414477

Tunsjø HS, Kalyanasundaram S, Worren MM, Leegaard TM, Moen AEF (2016)
High frequency of occupied attB regions in Norwegian Staphylococcus aureus isolates supports a two-step MRSA screening algorithm
Eur J Clin Microbiol Infect Dis, 36 (1), 65-74
DOI 10.1007/s10096-016-2771-0, PubMed 27638009

Williamson A, De Santi C, Altermark B, Karlsen C, Hjerde E (2016)
Complete genome sequence of Halomonas sp. R5-57
Stand Genomic Sci, 11 (1), 62
DOI 10.1186/s40793-016-0192-4, PubMed 27610212

Publications 2015

Alioto TS, Buchhalter I, Derdak S, Hutter B, Eldridge MD, Hovig E, Heisler LE, Beck TA, Simpson JT, Tonon L, Sertier AS, Patch AM, Jäger N, Ginsbach P, Drews R, Paramasivam N, Kabbe R, Chotewutmontri S, Diessl N, Previti C, Schmidt S, Brors B, Feuerbach L, Heinold M, Gröbner S et al. (2015)
A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing
Nat Commun, 6, 10001
DOI 10.1038/ncomms10001, PubMed 26647970

Hansen MF, Johansen J, Bjørnevoll I, Sylvander AE, Steinsbekk KS, Sætrom P, Sandvik AK, Drabløs F, Sjursen W (2015)
A novel POLE mutation associated with cancers of colon, pancreas, ovaries and small intestine
Fam Cancer, 14 (3), 437-48
DOI 10.1007/s10689-015-9803-2, PubMed 25860647

Hjerde E, Karlsen C, Sørum H, Parkhill J, Willassen NP, Thomson NR (2015)
Co-cultivation and transcriptome sequencing of two co-existing fish pathogens Moritella viscosa and Aliivibrio wodanis
BMC Genomics, 16 (1), 447
DOI 10.1186/s12864-015-1669-z, PubMed 26059548

Landin MA, Nygård S, Shabestari MG, Babaie E, Reseland JE, Osmundsen H (2015)
Mapping the global mRNA transcriptome during development of the murine first molar
Front Genet, 6, 47
DOI 10.3389/fgene.2015.00047, PubMed 25852735

Lau C, Nygård S, Fure H, Olstad OK, Holden M, Lappegård KT, Brekke OL, Espevik T, Hovig E, Mollnes TE (2015)
CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray
PLoS One, 10 (2), e0117261
DOI 10.1371/journal.pone.0117261, PubMed 25706641

Lau C, Olstad OK, Holden M, Nygård S, Fure H, Lappegård KT, Brekke OL, Espevik T, Hovig E, Mollnes TE (2015)
Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response
Genom Data, 5, 176-83
DOI 10.1016/j.gdata.2015.05.019, PubMed 26484252

Munkley J, Oltean S, Vodák D, Wilson BT, Livermore KE, Zhou Y, Star E, Floros VI, Johannessen B, Knight B, McCullagh P, McGrath J, Crundwell M, Skotheim RI, Robson CN, Leung HY, Harries LW, Rajan P, Mills IG, Elliott DJ (2015)
The androgen receptor controls expression of the cancer-associated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer
Oncotarget, 6 (33), 34358-74
DOI 10.18632/oncotarget.6024, PubMed 26452038

Omland T, de Lemos JA, Holmen OL, Dalen H, Benth JŠ, Nygård S, Hveem K, Røsjø H (2015)
Impact of sex on the prognostic value of high-sensitivity cardiac troponin I in the general population: the HUNT study
Clin Chem, 61 (4), 646-56
DOI 10.1373/clinchem.2014.234369, PubMed 25695851

Ricanek P, Lunde LK, Frye SA, Støen M, Nygård S, Morth JP, Rydning A, Vatn MH, Amiry-Moghaddam M, Tønjum T (2015)
Reduced expression of aquaporins in human intestinal mucosa in early stage inflammatory bowel disease
Clin Exp Gastroenterol, 8, 49-67
DOI 10.2147/CEG.S70119, PubMed 25624769

Ringh M, Rosenqvist M, Hollenberg J, Jonsson M, Fredman D, Nordberg P, Järnbert-Pettersson H, Hasselqvist-Ax I, Riva G, Svensson L (2015)
Mobile-phone dispatch of laypersons for CPR in out-of-hospital cardiac arrest
N Engl J Med, 372 (24), 2316-25
DOI 10.1056/NEJMoa1406038, PubMed 26061836

Rustad EH, Dai HY, Hov H, Coward E, Beisvag V, Myklebost O, Hovig E, Nakken S, Vodák D, Meza-Zepeda LA, Sandvik AK, Wader KF, Misund K, Sundan A, Aarset H, Waage A (2015)
BRAF V600E mutation in early-stage multiple myeloma: good response to broad acting drugs and no relation to prognosis
Blood Cancer J, 5 (3), e299
DOI 10.1038/bcj.2015.24, PubMed 25794135

Sevilla LM, Latorre V, Carceller E, Boix J, Vodák D, Mills IG, Pérez P (2015)
Glucocorticoid receptor and Klf4 co-regulate anti-inflammatory genes in keratinocytes
Mol Cell Endocrinol, 412, 281-9
DOI 10.1016/j.mce.2015.05.015, PubMed 26001834

Simpson MR, Brede G, Johansen J, Johnsen R, Storrø O, Sætrom P, Øien T (2015)
Human Breast Milk miRNA, Maternal Probiotic Supplementation and Atopic Dermatitis in Offspring
PLoS One, 10 (12), e0143496
DOI 10.1371/journal.pone.0143496, PubMed 26657066

Stangeland B, Mughal AA, Grieg Z, Sandberg CJ, Joel M, Nygård S, Meling T, Murrell W, Vik Mo EO, Langmoen IA (2015)
Combined expressional analysis, bioinformatics and targeted proteomics identify new potential therapeutic targets in glioblastoma stem cells
Oncotarget, 6 (28), 26192-215
DOI 10.18632/oncotarget.4613, PubMed 26295306

Strøm TB, Laerdahl JK, Leren TP (2015)
Mutation p.L799R in the LDLR, which affects the transmembrane domain of the LDLR, prevents membrane insertion and causes secretion of the mutant LDLR
Hum Mol Genet, 24 (20), 5836-44
DOI 10.1093/hmg/ddv304, PubMed 26220972

Vesterhus M, Hov JR, Holm A, Schrumpf E, Nygård S, Godang K, Andersen IM, Naess S, Thorburn D, Saffioti F, Vatn M, Gilja OH, Lund-Johansen F, Syversveen T, Brabrand K, Parés A, Ponsioen CY, Pinzani M, Färkkilä M, Moum B, Ueland T, Røsjø H, Rosenberg W, Boberg KM, Karlsen TH (2015)
Enhanced liver fibrosis score predicts transplant-free survival in primary sclerosing cholangitis
Hepatology, 62 (1), 188-97
DOI 10.1002/hep.27825, PubMed 25833813

Williamson A, Hjerde E, Kahlke T (2015)
Analysis of the distribution and evolution of the ATP-dependent DNA ligases of bacteria delineates a distinct phylogenetic group 'Lig E'
Mol Microbiol, 99 (2), 274-90
DOI 10.1111/mmi.13229, PubMed 26412580

Publications 2014

Bergseng E, Dørum S, Arntzen MØ, Nielsen M, Nygård S, Buus S, de Souza GA, Sollid LM (2014)
Different binding motifs of the celiac disease-associated HLA molecules DQ2.5, DQ2.2, and DQ7.5 revealed by relative quantitative proteomics of endogenous peptide repertoires
Immunogenetics, 67 (2), 73-84
DOI 10.1007/s00251-014-0819-9, PubMed 25502872

Bjerga GE, Hjerde E, De Santi C, Williamson AK, Smalås AO, Willassen NP, Altermark B (2014)
High quality draft genome sequence of Streptomyces sp. strain AW19M42 isolated from a sea squirt in Northern Norway
Stand Genomic Sci, 9 (3), 676-86
DOI 10.4056/sigs.5038901, PubMed 25197453

Bjerga GEK, Hjerde E, De Santi C, Williamson AK, Smalas AO, Willassen NP, Altermark B (2014)
High quality draft genome sequence of Streptomyces sp. strain AW19M42 isolated from a sea squirt in Northern Norway
Stand. Genomic Sci., 9 (3)
DOI 10.4056/sigs.5039801

Cavanagh JP, Hjerde E, Holden MT, Kahlke T, Klingenberg C, Flægstad T, Parkhill J, Bentley SD, Sollid JU (2014)
Whole-genome sequencing reveals clonal expansion of multiresistant Staphylococcus haemolyticus in European hospitals
J Antimicrob Chemother, 69 (11), 2920-7
DOI 10.1093/jac/dku271, PubMed 25038069

Haugum K, Johansen J, Gabrielsen C, Brandal LT, Bergh K, Ussery DW, Drabløs F, Afset JE (2014)
Comparative genomics to delineate pathogenic potential in non-O157 Shiga toxin-producing Escherichia coli (STEC) from patients with and without haemolytic uremic syndrome (HUS) in Norway
PLoS One, 9 (10), e111788
DOI 10.1371/journal.pone.0111788, PubMed 25360710

Hillestad V, Espe EK, Cero F, Larsen KO, Sjaastad I, Nygård S, Skjønsberg OH, Christensen G (2014)
IL-18 neutralization during alveolar hypoxia improves left ventricular diastolic function in mice
Acta Physiol (Oxf), 213 (2), 492-504
DOI 10.1111/apha.12376, PubMed 25182570

Kashulin A, Sørum H, Hjerde E, Willassen NP (2014)
IS elements in Aliivibrio salmonicida LFI1238: occurrence, variability and impact on adaptability
Gene, 554 (1), 40-9
DOI 10.1016/j.gene.2014.10.019, PubMed 25447025

Mærk M, Johansen J, Ertesvåg H, Drabløs F, Valla S (2014)
Safety in numbers: multiple occurrences of highly similar homologs among Azotobacter vinelandii carbohydrate metabolism proteins probably confer adaptive benefits
BMC Genomics, 15 (1), 192
DOI 10.1186/1471-2164-15-192, PubMed 24625193

Nygård S, Reitan T, Clancy T, Nygaard V, Bjørnstad J, Skrbic B, Tønnessen T, Christensen G, Hovig E (2014)
Identifying pathogenic processes by integrating microarray data with prior knowledge
BMC Bioinformatics, 15, 115
DOI 10.1186/1471-2105-15-115, PubMed 24758699

Paulsen J, Sandve GK, Gundersen S, Lien TG, Trengereid K, Hovig E (2014)
HiBrowse: multi-purpose statistical analysis of genome-wide chromatin 3D organization
Bioinformatics, 30 (11), 1620-2
DOI 10.1093/bioinformatics/btu082, PubMed 24511080

Strøm TB, Tveten K, Laerdahl JK, Leren TP (2014)
Mutation G805R in the transmembrane domain of the LDL receptor gene causes familial hypercholesterolemia by inducing ectodomain cleavage of the LDL receptor in the endoplasmic reticulum
FEBS Open Bio, 4, 321-7
DOI 10.1016/j.fob.2014.03.007, PubMed 24918045

Wollen EJ, Kwinta P, Bik-Multanowski M, Madetko-Talowska A, Sejersted Y, Wright MS, Günther CC, Nygård S, Saugstad OD, Pietrzyk JJ (2014)
Hypoxia-reoxygenation affects whole-genome expression in the newborn eye
Invest Ophthalmol Vis Sci, 55 (3), 1393-401
DOI 10.1167/iovs.13-13159, PubMed 24458145

Wu X, Sagave J, Rutkovskiy A, Haugen F, Baysa A, Nygård S, Czibik G, Dahl CP, Gullestad L, Vaage J, Valen G (2014)
Expression of bone morphogenetic protein 4 and its receptors in the remodeling heart
Life Sci, 97 (2), 145-54
DOI 10.1016/j.lfs.2013.12.030, PubMed 24398041

Zeissig S, Petersen BS, Tomczak M, Melum E, Huc-Claustre E, Dougan SK, Laerdahl JK, Stade B, Forster M, Schreiber S, Weir D, Leichtner AM, Franke A, Blumberg RS (2014)
Early-onset Crohn's disease and autoimmunity associated with a variant in CTLA-4
Gut, 64 (12), 1889-97
DOI 10.1136/gutjnl-2014-308541, PubMed 25367873

Publications 2013

Andreassen R, Worren MM, Høyheim B (2013)
Discovery and characterization of miRNA genes in Atlantic salmon (Salmo salar) by use of a deep sequencing approach
BMC Genomics, 14, 482
DOI 10.1186/1471-2164-14-482, PubMed 23865519

Backe PH, Simm R, Laerdahl JK, Dalhus B, Fagerlund A, Okstad OA, Rognes T, Alseth I, Kolstø AB, Bjørås M (2013)
A new family of proteins related to the HEAT-like repeat DNA glycosylases with affinity for branched DNA structures
J Struct Biol, 183 (1), 66-75
DOI 10.1016/j.jsb.2013.04.007, PubMed 23623903

Bjørkeng EK, Hjerde E, Pedersen T, Sundsfjord A, Hegstad K (2013)
ICESluvan, a 94-kilobase mosaic integrative conjugative element conferring interspecies transfer of VanB-type glycopeptide resistance, a novel bacitracin resistance locus, and a toxin-antitoxin stabilization system
J Bacteriol, 195 (23), 5381-90
DOI 10.1128/JB.02165-12, PubMed 24078615

Clancy T, Rødland EA, Nygard S, Hovig E (2013)
Predicting physical interactions between protein complexes
Mol Cell Proteomics, 12 (6), 1723-34
DOI 10.1074/mcp.O112.019828, PubMed 23438732

Ellinghaus D, Folseraas T, Holm K, Ellinghaus E, Melum E, Balschun T, Laerdahl JK, Shiryaev A, Gotthardt DN, Weismüller TJ, Schramm C, Wittig M, Bergquist A, Björnsson E, Marschall HU, Vatn M, Teufel A, Rust C, Gieger C, Wichmann HE, Runz H, Sterneck M, Rupp C, Braun F, Weersma RK et al. (2013)
Genome-wide association analysis in primary sclerosing cholangitis and ulcerative colitis identifies risk loci at GPR35 and TCF4
Hepatology, 58 (3), 1074-83
DOI 10.1002/hep.25977, PubMed 22821403

Hjerde E, Pierechod MM, Williamson AK, Bjerga GE, Willassen NP, Smalås AO, Altermark B (2013)
Draft Genome Sequence of the Actinomycete Rhodococcus sp. Strain AW25M09, Isolated from the Hadsel Fjord, Northern Norway
Genome Announc, 1 (2), e0005513
DOI 10.1128/genomeA.00055-13, PubMed 23516194

Lewin A, Johansen J, Wentzel A, Kotlar HK, Drabløs F, Valla S (2013)
The microbial communities in two apparently physically separated deep subsurface oil reservoirs show extensive DNA sequence similarities
Environ Microbiol, 16 (2), 545-58
DOI 10.1111/1462-2920.12181, PubMed 23827055

Sandve GK, Gundersen S, Johansen M, Glad IK, Gunathasan K, Holden L, Holden M, Liestøl K, Nygård S, Nygaard V, Paulsen J, Rydbeck H, Trengereid K, Clancy T, Drabløs F, Ferkingstad E, Kalas M, Lien T, Rye MB, Frigessi A, Hovig E (2013)
The Genomic HyperBrowser: an analysis web server for genome-scale data
Nucleic Acids Res, 41 (Web Server issue), W133-41
DOI 10.1093/nar/gkt342, PubMed 23632163

Schee K, Lorenz S, Worren MM, Günther CC, Holden M, Hovig E, Fodstad O, Meza-Zepeda LA, Flatmark K (2013)
Deep Sequencing the MicroRNA Transcriptome in Colorectal Cancer
PLoS One, 8 (6), e66165
DOI 10.1371/journal.pone.0066165, PubMed 23824282

Subramanian S, Sztromwasser P, Puntervoll P, Petersen K (2013)
Pipelined data-flow delegated orchestration for data-intensive eScience workflows
Int. J. Web Inf. Syst., 9 (3), 204-+
DOI 10.1108/IJWIS-05-2013-0012

Søberg K, Jahnsen T, Rognes T, Skålhegg BS, Laerdahl JK (2013)
Evolutionary paths of the cAMP-dependent protein kinase (PKA) catalytic subunits
PLoS One, 8 (4), e60935
DOI 10.1371/journal.pone.0060935, PubMed 23593352

Vistnes M, Høiseth AD, Røsjø H, Nygård S, Pettersen E, Søyseth V, Hurlen P, Christensen G, Omland T (2013)
Lack of pro-inflammatory cytokine mobilization predicts poor prognosis in patients with acute heart failure
Cytokine, 61 (3), 962-9
DOI 10.1016/j.cyto.2013.01.006, PubMed 23415671

Wollen EJ, Sejersted Y, Wright MS, Bik-Multanowski M, Madetko-Talowska A, Günther CC, Nygård S, Kwinta P, Pietrzyk JJ, Saugstad OD (2013)
Transcriptome profiling of the newborn mouse lung after hypoxia and reoxygenation: hyperoxic reoxygenation affects mTOR signaling pathway, DNA repair, and JNK-pathway regulation
Pediatr Res, 74 (5), 536-44
DOI 10.1038/pr.2013.140, PubMed 23999071

Wollen EJ, Sejersted Y, Wright MS, Madetko-Talowska A, Bik-Multanowski M, Kwinta P, Günther CC, Nygård S, Løberg EM, Ystgaard MB, Pietrzyk JJ, Saugstad OD (2013)
Transcriptome profiling of the newborn mouse brain after hypoxia-reoxygenation: hyperoxic reoxygenation induces inflammatory and energy failure responsive genes
Pediatr Res, 75 (4), 517-26
DOI 10.1038/pr.2013.249, PubMed 24375083

Zegeye ED, Balasingham SV, Laerdahl JK, Homberset H, Kristiansen PE, Tønjum T (2013)
Effects of conserved residues and naturally occurring mutations on Mycobacterium tuberculosis RecG helicase activity
Microbiology (Reading), 160 (Pt 1), 217-227
DOI 10.1099/mic.0.072140-0, PubMed 24169816

Publications 2012

Ahmad R, Hansen GÅ, Hansen H, Hjerde E, Pedersen HL, Paulsen SM, Nyrud ML, Strauss A, Willassen NP, Haugen P (2012)
Prediction, microarray and northern blot analyses identify new intergenic small RNAs in Aliivibrio salmonicida
J Mol Microbiol Biotechnol, 22 (6), 352-60
DOI 10.1159/000345769, PubMed 23295256

Balasingham SV, Zegeye ED, Homberset H, Rossi ML, Laerdahl JK, Bohr VA, Tønjum T (2012)
Enzymatic activities and DNA substrate specificity of Mycobacterium tuberculosis DNA helicase XPB
PLoS One, 7 (5), e36960
DOI 10.1371/journal.pone.0036960, PubMed 22615856

Bjornsdottir B, Hjerde E, Bragason BT, Gudmundsdottir T, Willassen NP, Gudmundsdottir BK (2012)
Identification of type VI secretion systems in Moritella viscosa
Vet Microbiol, 158 (3-4), 436-42
DOI 10.1016/j.vetmic.2012.02.030, PubMed 22425489

Folseraas T, Melum E, Rausch P, Juran BD, Ellinghaus E, Shiryaev A, Laerdahl JK, Ellinghaus D, Schramm C, Weismüller TJ, Gotthardt DN, Hov JR, Clausen OP, Weersma RK, Janse M, Boberg KM, Björnsson E, Marschall HU, Cleynen I, Rosenstiel P, Holm K, Teufel A, Rust C, Gieger C, Wichmann HE et al. (2012)
Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci
J Hepatol, 57 (2), 366-75
DOI 10.1016/j.jhep.2012.03.031, PubMed 22521342

Hansen GA, Ahmad R, Hjerde E, Fenton CG, Willassen NP, Haugen P (2012)
Expression profiling reveals Spot 42 small RNA as a key regulator in the central metabolism of Aliivibrio salmonicida
BMC Genomics, 13, 37
DOI 10.1186/1471-2164-13-37, PubMed 22272603

Kahlke T, Goesmann A, Hjerde E, Willassen NP, Haugen P (2012)
Unique core genomes of the bacterial family vibrionaceae: insights into niche adaptation and speciation
BMC Genomics, 13, 179
DOI 10.1186/1471-2164-13-179, PubMed 22574681

Korvald H, Falnes PØ, Laerdahl JK, Bjørås M, Alseth I (2012)
The Schizosaccharomyces pombe AlkB homolog Abh1 exhibits AP lyase activity but no demethylase activity
DNA Repair (Amst), 11 (5), 453-62
DOI 10.1016/j.dnarep.2012.01.014, PubMed 22365419

Lindell K, Fahlgren A, Hjerde E, Willassen NP, Fällman M, Milton DL (2012)
Lipopolysaccharide O-antigen prevents phagocytosis of Vibrio anguillarum by rainbow trout (Oncorhynchus mykiss) skin epithelial cells
PLoS One, 7 (5), e37678
DOI 10.1371/journal.pone.0037678, PubMed 22662189

Pietrzyk JJ, Kwinta P, Bik-Multanowski M, Madetko-Talowska A, Jagła M, Tomasik T, Mitkowska Z, Wollen EJ, Nygård S, Saugstad OD (2012)
New insight into the pathogenesis of retinopathy of prematurity: assessment of whole-genome expression
Pediatr Res, 73 (4 Pt 1), 476-83
DOI 10.1038/pr.2012.195, PubMed 23269122

Rutkovskiy A, Mariero LH, Nygård S, Stensløkken KO, Valen G, Vaage J (2012)
Transient hyperosmolality modulates expression of cardiac aquaporins
Biochem Biophys Res Commun, 425 (1), 70-5
DOI 10.1016/j.bbrc.2012.07.052, PubMed 22820194

Røsjø H, Nygård S, Kaukonen KM, Karlsson S, Stridsberg M, Ruokonen E, Pettilä V, Omland T, FINNSEPSIS Study Group (2012)
Prognostic value of chromogranin A in severe sepsis: data from the FINNSEPSIS study
Intensive Care Med, 38 (5), 820-9
DOI 10.1007/s00134-012-2546-8, PubMed 22491939

Røsjø H, Tamm NN, Kravdal G, Seferian KR, Høiseth AD, Nygård S, Badr P, Røysland R, Omland T (2012)
Diagnostic utility of a single-epitope sandwich B-type natriuretic peptide assay in stable coronary artery disease: data from the Akershus Cardiac Examination (ACE) 1 Study
Clin Biochem, 45 (16-17), 1269-75
DOI 10.1016/j.clinbiochem.2012.05.010, PubMed 22609895

Røysland R, Kravdal G, Høiseth AD, Nygård S, Badr P, Hagve TA, Omland T, Røsjø H (2012)
Cardiac troponin T levels and exercise stress testing in patients with suspected coronary artery disease: the Akershus Cardiac Examination (ACE) 1 study
Clin Sci (Lond), 122 (12), 599-606
DOI 10.1042/CS20110557, PubMed 22239123

Skrbic B, Bjørnstad JL, Marstein HS, Carlson CR, Sjaastad I, Nygård S, Bjørnstad S, Christensen G, Tønnessen T (2012)
Differential regulation of extracellular matrix constituents in myocardial remodeling with and without heart failure following pressure overload
Matrix Biol, 32 (2), 133-42
DOI 10.1016/j.matbio.2012.11.011, PubMed 23220517

Søberg K, Larsen AC, Diskar M, Backe PH, Bjørås M, Jahnsen T, Laerdahl JK, Rognes T, Herberg FW, Skålhegg BS (2012)
Identification and characterization of novel mutations in the human gene encoding the catalytic subunit Calpha of protein kinase A (PKA)
PLoS One, 7 (4), e34838
DOI 10.1371/journal.pone.0034838, PubMed 22514673

Waehre A, Vistnes M, Sjaastad I, Nygård S, Husberg C, Lunde IG, Aukrust P, Yndestad A, Vinge LE, Behmen D, Neukamm C, Brun H, Thaulow E, Christensen G (2012)
Chemokines regulate small leucine-rich proteoglycans in the extracellular matrix of the pressure-overloaded right ventricle
J Appl Physiol (1985), 112 (8), 1372-82
DOI 10.1152/japplphysiol.01350.2011, PubMed 22345433

Zegeye ED, Balasingham SV, Laerdahl JK, Homberset H, Tønjum T (2012)
Mycobacterium tuberculosis RecG binds and unwinds model DNA substrates with a preference for Holliday junctions
Microbiology (Reading), 158 (Pt 8), 1982-1993
DOI 10.1099/mic.0.058693-0, PubMed 22628485

Publications 2011

Finsen AV, Lunde IG, Sjaastad I, Østli EK, Lyngra M, Jarstadmarken HO, Hasic A, Nygård S, Wilcox-Adelman SA, Goetinck PF, Lyberg T, Skrbic B, Florholmen G, Tønnessen T, Louch WE, Djurovic S, Carlson CR, Christensen G (2011)
Syndecan-4 is essential for development of concentric myocardial hypertrophy via stretch-induced activation of the calcineurin-NFAT pathway
PLoS One, 6 (12), e28302
DOI 10.1371/journal.pone.0028302, PubMed 22164265

Holla ØL, Cameron J, Tveten K, Strøm TB, Berge KE, Laerdahl JK, Leren TP (2011)
Role of the C-terminal domain of PCSK9 in degradation of the LDL receptors
J Lipid Res, 52 (10), 1787-94
DOI 10.1194/jlr.M018093, PubMed 21771976

Kotlar HK, Lewin A, Johansen J, Throne-Holst M, Haverkamp T, Markussen S, Winnberg A, Ringrose P, Aakvik T, Ryeng E, Jakobsen K, Drabløs F, Valla S (2011)
High coverage sequencing of DNA from microorganisms living in an oil reservoir 2.5 kilometres subsurface
Environ Microbiol Rep, 3 (6), 674-81
DOI 10.1111/j.1758-2229.2011.00279.x, PubMed 23761356

Sandve GK, Ferkingstad E, Nygård S (2011)
Sequential Monte Carlo multiple testing
Bioinformatics, 27 (23), 3235-41
DOI 10.1093/bioinformatics/btr568, PubMed 21998154

Star B, Nederbragt AJ, Jentoft S, Grimholt U, Malmstrøm M, Gregers TF, Rounge TB, Paulsen J, Solbakken MH, Sharma A, Wetten OF, Lanzén A, Winer R, Knight J, Vogel JH, Aken B, Andersen O, Lagesen K, Tooming-Klunderud A, Edvardsen RB, Tina KG, Espelund M, Nepal C, Previti C, Karlsen BO et al. (2011)
The genome sequence of Atlantic cod reveals a unique immune system
Nature, 477 (7363), 207-10
DOI 10.1038/nature10342, PubMed 21832995

Sztromwasser P, Puntervoll P, Petersen K (2011)
Data partitioning enables the use of standard SOAP Web Services in genome-scale workflows
J Integr Bioinform, 8 (2), 163
DOI 10.2390/biecoll-jib-2011-163, PubMed 21788681

Tveten K, Holla ØL, Cameron J, Strøm TB, Berge KE, Laerdahl JK, Leren TP (2011)
Interaction between the ligand-binding domain of the LDL receptor and the C-terminal domain of PCSK9 is required for PCSK9 to remain bound to the LDL receptor during endosomal acidification
Hum Mol Genet, 21 (6), 1402-9
DOI 10.1093/hmg/ddr578, PubMed 22156580

Waehre A, Halvorsen B, Yndestad A, Husberg C, Sjaastad I, Nygård S, Dahl CP, Ahmed MS, Finsen AV, Reims H, Louch WE, Hilfiker-Kleiner D, Vinge LE, Roald B, Attramadal H, Lipp M, Gullestad L, Aukrust P, Christensen G (2011)
Lack of chemokine signaling through CXCR5 causes increased mortality, ventricular dilatation and deranged matrix during cardiac pressure overload
PLoS One, 6 (4), e18668
DOI 10.1371/journal.pone.0018668, PubMed 21533157

Weber B, Lindell K, El Qaidi S, Hjerde E, Willassen NP, Milton DL (2011)
The phosphotransferase VanU represses expression of four qrr genes antagonizing VanO-mediated quorum-sensing regulation in Vibrio anguillarum
Microbiology (Reading), 157 (Pt 12), 3324-3339
DOI 10.1099/mic.0.051011-0, PubMed 21948044

Publications 2010

Bratlie MS, Johansen J, Drabløs F (2010)
Relationship between operon preference and functional properties of persistent genes in bacterial genomes
BMC Genomics, 11, 71
DOI 10.1186/1471-2164-11-71, PubMed 20109203

Bratlie MS, Johansen J, Sherman BT, Huang da W, Lempicki RA, Drabløs F (2010)
Gene duplications in prokaryotes can be associated with environmental adaptation
BMC Genomics, 11, 588
DOI 10.1186/1471-2164-11-588, PubMed 20961426

Hougen K, Aronsen JM, Stokke MK, Enger U, Nygard S, Andersson KB, Christensen G, Sejersted OM, Sjaastad I (2010)
Cre-loxP DNA recombination is possible with only minimal unspecific transcriptional changes and without cardiomyopathy in Tg(alphaMHC-MerCreMer) mice
Am J Physiol Heart Circ Physiol, 299 (5), H1671-8
DOI 10.1152/ajpheart.01155.2009, PubMed 20802136

Publications 2009

Bjerner J, Theodorsson E, Hovig E, Kallner A (2009)
Non-parametric estimation of reference intervals in small non-Gaussian sample sets
Accredit. Qual. Assur., 14 (4), 185-192
DOI 10.1007/s00769-009-0490-2

Trösse C, Waagbø R, Breck O, Stavrum AK, Petersen K, Olsvik PA (2009)
Genome-wide transcription analysis of histidine-related cataract in Atlantic salmon (Salmo salar L)
Mol Vis, 15, 1332-50
PubMed 19597568

van Beijnum JR, Petersen K, Griffioen AW (2009)
Tumor endothelium is characterized by a matrix remodeling signature
Front Biosci (Schol Ed), 1 (1), 216-25
DOI 10.2741/S21, PubMed 19482697

Publications 2008

Klepper K, Sandve GK, Abul O, Johansen J, Drablos F (2008)
Assessment of composite motif discovery methods
BMC Bioinformatics, 9, 123
DOI 10.1186/1471-2105-9-123, PubMed 18302777

Olsvik PA, Lie KK, Mykkeltvedt E, Samuelsen OB, Petersen K, Stavrum AK, Lunestad BT (2008)
Pharmacokinetics and transcriptional effects of the anti-salmon lice drug emamectin benzoate in Atlantic salmon (Salmo salar L.)
BMC Pharmacol, 8, 16
DOI 10.1186/1471-2210-8-16, PubMed 18786259

Stavrum AK, Petersen K, Jonassen I, Dysvik B (2008)
Analysis of gene-expression data using J-Express
Curr Protoc Bioinformatics, Chapter 7, Unit 7.3
DOI 10.1002/0471250953.bi0703s21, PubMed 18428687