Publications (original articles or review articles) published in 2023 from OUS - Division of Laboratory Medicine
341 publications found
Adipose-derived Stromal Cells Preserve Pancreatic Islet Function in A Transplantable 3d Bioprinted Scaffold
Adv Healthc Mater, e2300640 (in press)
DOI 10.1002/adhm.202300640, PubMed 37781993
hSSB1 (NABP2/OBFC2B) modulates the DNA damage and androgen-induced transcriptional response in prostate cancer
Prostate, 83 (7), 628-640
DOI 10.1002/pros.24496, PubMed 36811381
Longitudinal transcriptomic analysis of human cortical spheroids identifies axonal dysregulation in the prenatal brain as a mediator of genetic risk for schizophrenia
Biol Psychiatry (in press)
DOI 10.1016/j.biopsych.2023.08.017, PubMed 37661009
Aagenaes syndrome/lymphedema cholestasis syndrome 1 is caused by a founder variant in the 5'-untranslated region of UNC45A
J Hepatol, 79 (4), 945-954
DOI 10.1016/j.jhep.2023.05.037, PubMed 37328071
Pancreatic stellate cell-induced gemcitabine resistance in pancreatic cancer is associated with LDHA- and MCT4-mediated enhanced glycolysis
Cancer Cell Int, 23 (1), 9
DOI 10.1186/s12935-023-02852-7, PubMed 36658582
Expression of transglutaminase 2 in human gut epithelial cells: Implications for coeliac disease
PLoS One, 18 (6), e0287662
DOI 10.1371/journal.pone.0287662, PubMed 37368893
Long-term survival after liver transplantation in patients with common variable immunodeficiency
Liver Transpl, 29 (8), 894-899
DOI 10.1097/LVT.0000000000000130, PubMed 36932715
Novel enhancers of guanylyl cyclase-A activity acting via allosteric modulation
Br J Pharmacol (in press)
DOI 10.1111/bph.16203, PubMed 37522273
External multicentre validation of pseudomyxoma peritonei PSOGI-Ki67 classification
Eur J Surg Oncol, 49 (8), 1481-1488
DOI 10.1016/j.ejso.2023.03.206, PubMed 36935222
Electrical stimulation alters DNA methylation and promotes neurite outgrowth
J Cell Biochem (in press)
DOI 10.1002/jcb.30462, PubMed 37642194
Mutant P53 in the formation and progression of the tumor microenvironment: Friend or foe
Life Sci, 315, 121361
DOI 10.1016/j.lfs.2022.121361, PubMed 36608871
Schematic sectioning approaches for corneal and retinal surfaces used in ophthalmology and vision-related clinical practice and research
Exp Eye Res, 230, 109442
DOI 10.1016/j.exer.2023.109442, PubMed 36940902
Comparison of Novel Wide-Field In Vivo Corneal Confocal Microscopy With Skin Biopsy for Assessing Peripheral Neuropathy in Type 2 Diabetes
Diabetes, 72 (7), 908-917
DOI 10.2337/db22-0863, PubMed 37058418
Ocular Surface Homeostasis After Scleral Lens Usage
Eye Contact Lens (in press)
DOI 10.1097/ICL.0000000000001027, PubMed 37651199
Genome-wide analysis of anorexia nervosa and major psychiatric disorders and related traits reveals genetic overlap and identifies novel risk loci for anorexia nervosa
Transl Psychiatry, 13 (1), 291
DOI 10.1038/s41398-023-02585-1, PubMed 37658054
Time- and Sex-Dependent Effects of Fingolimod Treatment in a Mouse Model of Alzheimer's Disease
Biomolecules, 13 (2)
DOI 10.3390/biom13020331, PubMed 36830699
Functional analyses of rare germline BRCA1 variants by transcriptional activation and homologous recombination repair assays
BMC Cancer, 23 (1), 368
DOI 10.1186/s12885-023-10790-w, PubMed 37085799
The neoepitope of the complement C5b-9 Membrane Attack Complex is formed by proximity of adjacent ancillary regions of C9
Commun Biol, 6 (1), 42
DOI 10.1038/s42003-023-04431-y, PubMed 36639734
Cellular and Genomic Features of Muscle Differentiation from Isogenic Fibroblasts and Myoblasts
Cells, 12 (15)
DOI 10.3390/cells12151995, PubMed 37566074
Long-term outcome after surgical resection of non-high-risk gastrointestinal stromal tumours without adjuvant therapy
Br J Surg (in press)
DOI 10.1093/bjs/znad309, PubMed 37758514
Stochastic epithelial-mesenchymal transitions diversify non-cancerous lung cell behaviours
Transl Oncol, 37, 101760
DOI 10.1016/j.tranon.2023.101760, PubMed 37611490
Psychometric Properties and Diagnostic Associations of the Short-Form Community Assessment of Psychic Experiences in a Population-Based Sample of 29 021 Adult Men
Schizophr Bull, 49 (5), 1229-1238
DOI 10.1093/schbul/sbad074, PubMed 37262330
Wnt/β-Catenin Signaling Activation Induces Differentiation in Human Limbal Epithelial Stem Cells Cultured Ex Vivo
Biomedicines, 11 (7)
DOI 10.3390/biomedicines11071829, PubMed 37509479
Reporting a novel growth hormone receptor gene variant in an Iranian consanguineous pedigree with Laron syndrome: a case report
BMC Endocr Disord, 23 (1), 155
DOI 10.1186/s12902-023-01388-1, PubMed 37474955
Dual inhibition of complement C5 and CD14 attenuates inflammation in a cord blood model
Pediatr Res, 94 (2), 512-519
DOI 10.1038/s41390-023-02489-2, PubMed 36725909
The effects of transitioning from immediate release to extended release cysteamine therapy in Norwegian patients with nephropathic cystinosis: a retrospective study
Pediatr Nephrol, 38 (11), 3671-3679
DOI 10.1007/s00467-023-06005-w, PubMed 37219641
Prediction of Age Older than 18 Years in Sub-adults by MRI Segmentation of 1st and 2nd Molars
Int J Legal Med, 137 (5), 1515-1526
DOI 10.1007/s00414-023-03055-5, PubMed 37402013
Age prediction in sub-adults based on MRI segmentation of 3rd molar tissue volumes
Int J Legal Med, 137 (3), 753-763
DOI 10.1007/s00414-023-02977-4, PubMed 36811675
Next-generation sequencing reveals mitogenome diversity in plasma extracellular vesicles from colorectal cancer patients
BMC Cancer, 23 (1), 650
DOI 10.1186/s12885-023-11092-x, PubMed 37438741
Cytomegalovirus High-risk Kidney Transplant Recipients Show No Difference in Long-term Outcomes Following Preemptive Versus Prophylactic Management
Transplantation, 107 (8), 1846-1853
DOI 10.1097/TP.0000000000004615, PubMed 37211633
No signs of neurodegenerative effects in 15q11.2 BP1-BP2 copy number variant carriers in the UK Biobank
Transl Psychiatry, 13 (1), 61
DOI 10.1038/s41398-023-02358-w, PubMed 36807331
Beyond the Global Brain Differences: Intra-individual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers
Biol Psychiatry (in press)
DOI 10.1016/j.biopsych.2023.08.018, PubMed 37661008
Heroin metabolism in human blood and its impact for the design of an immunotherapeutic approach against heroin effects
Basic Clin Pharmacol Toxicol (in press)
DOI 10.1111/bcpt.13926, PubMed 37452619
'High proliferative cribriform prostate cancer' defines a patient subgroup with an inferior prognosis
Histopathology (in press)
DOI 10.1111/his.15012, PubMed 37501635
The association between infant salivary cortisol and parental presence in the neonatal intensive care unit during and after COVID-19 visitation restrictions: A cross-sectional study
Early Hum Dev, 182, 105788
DOI 10.1016/j.earlhumdev.2023.105788, PubMed 37224589
Improvement in Neisseria gonorrhoeae culture rates by bedside inoculation and incubation at a clinic for sexually transmitted infections
Ann Clin Microbiol Antimicrob, 22 (1), 27
DOI 10.1186/s12941-023-00576-0, PubMed 37072830
HLA-DQ2 is associated with anti-drug antibody formation to infliximab in patients with immune-mediated inflammatory diseases
J Intern Med, 293 (5), 648-655
DOI 10.1111/joim.13616, PubMed 36843323
Clinical and biochemical impact of vitamin B6 deficiency in primary sclerosing cholangitis before and after liver transplantation
J Hepatol, 79 (4), 955-966
DOI 10.1016/j.jhep.2023.05.038, PubMed 37328069
Pump-less, recirculating organ-on-a-chip (rOoC) platform
Lab Chip, 23 (4), 591-608
DOI 10.1039/d2lc00919f, PubMed 36655405
Escherichia coli-induced inflammatory responses are temperature-dependent in human whole blood ex vivo
Mol Immunol, 157, 70-77
DOI 10.1016/j.molimm.2023.03.006, PubMed 37001293
Human small intestine contains 2 functionally distinct regulatory T-cell subsets
J Allergy Clin Immunol, 152 (1), 278-289.e6
DOI 10.1016/j.jaci.2023.02.030, PubMed 36893861
CD47 and CD68 expression in breast cancer is associated with tumor-infiltrating lymphocytes, blood vessel invasion, detection mode, and prognosis
J Pathol Clin Res, 9 (3), 151-164
DOI 10.1002/cjp2.309, PubMed 36598153
The relationship between cannabis use, schizophrenia, and bipolar disorder: a genetically informed study
Lancet Psychiatry, 10 (6), 441-451
DOI 10.1016/S2215-0366(23)00143-8, PubMed 37208114
Identification of gluten T cell epitopes driving celiac disease
Sci Adv, 9 (4), eade5800
DOI 10.1126/sciadv.ade5800, PubMed 36696493
Neurological manifestations of COVID-19 in adults and children
Brain, 146 (4), 1648-1661
DOI 10.1093/brain/awac332, PubMed 36087305
The Role of Procalcitonin as an Antimicrobial Stewardship Tool in Patients Hospitalized with Seasonal Influenza
Antibiotics (Basel), 12 (3)
DOI 10.3390/antibiotics12030573, PubMed 36978440
SigH stress response mediates killing of Mycobacterium tuberculosis by activating nitronaphthofuran prodrugs via induction of Mrx2 expression
Nucleic Acids Res, 51 (1), 144-165
DOI 10.1093/nar/gkac1173, PubMed 36546765
Fourier transform infrared spectroscopy; can it be used as a rapid typing method of Neisseria gonorrhoeae?
J Microbiol Methods, 205, 106675
DOI 10.1016/j.mimet.2023.106675, PubMed 36681126
Non-Coding RNA in Salivary Extracellular Vesicles: A New Frontier in Sjögren's Syndrome Diagnostics?
Int J Mol Sci, 24 (17)
DOI 10.3390/ijms241713409, PubMed 37686214
Lipopolysaccharide Primes Human Macrophages for Noncanonical Inflammasome-Induced Extracellular Vesicle Secretion
J Immunol, 210 (3), 322-334
DOI 10.4049/jimmunol.2200444, PubMed 36525001
Stage I epithelial or stromal type Wilms tumors are low risk tumors: An analysis of patients treated on the SIOP-WT-2001 protocol in the UK-CCLG and GPOH studies (2001-2020)
Cancer, 129 (12), 1930-1938
DOI 10.1002/cncr.34734, PubMed 36929497
Clinical and Biochemical Characteristics of Untreated Adult Patients With Resistance to Thyroid Hormone Alpha
J Endocr Soc, 7 (8), bvad089
DOI 10.1210/jendso/bvad089, PubMed 37469961
Clinical outcomes of antimicrobial resistance in cancer patients: a systematic review of multivariable models
BMC Infect Dis, 23 (1), 247
DOI 10.1186/s12879-023-08182-3, PubMed 37072711
Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry
Am J Hum Genet, 110 (7), 1200-1206
DOI 10.1016/j.ajhg.2023.05.010, PubMed 37311464
Separate Gut Plasma Cell Populations Produce Auto-Antibodies against Transglutaminase 2 and Transglutaminase 3 in Dermatitis Herpetiformis
Adv Sci (Weinh), 10 (25), e2300401
DOI 10.1002/advs.202300401, PubMed 37424036
Claudin-10 is a new candidate prognostic marker in metastatic high-grade serous carcinoma
Virchows Arch, 482 (6), 975-982
DOI 10.1007/s00428-023-03541-6, PubMed 37067588
Cancer Stem Cell Markers Are Differentially Expressed in Malignant Ovarian Germ Cell Tumors
Int J Gynecol Pathol (in press)
DOI 10.1097/PGP.0000000000000947, PubMed 37186896
Capturing the SARS-CoV-2 infection pyramid within the municipality of Rotterdam using longitudinal sewage surveillance
Sci Total Environ, 883, 163599
DOI 10.1016/j.scitotenv.2023.163599, PubMed 37100150
EYA4 promotes breast cancer progression and metastasis through its role in replication stress avoidance
Mol Cancer, 22 (1), 158
DOI 10.1186/s12943-023-01861-4, PubMed 37777742
The Local Tumor Microbiome Is Associated with Survival in Late-Stage Colorectal Cancer Patients
Microbiol Spectr, 11 (3), e0506622
DOI 10.1128/spectrum.05066-22, PubMed 37042765
Antibiotic Consumption in a Cohort of Hospitalized Adults with Viral Respiratory Tract Infection
Antibiotics (Basel), 12 (4)
DOI 10.3390/antibiotics12040788, PubMed 37107150
The microbiota of uterine biopsies, cytobrush and vaginal swabs at artificial insemination in Norwegian red cows
Theriogenology, 209, 115-125
DOI 10.1016/j.theriogenology.2023.06.024, PubMed 37390751
TNFα Activates the Liver X Receptor Signaling Pathway and Promotes Cholesterol Efflux from Human Brain Pericytes Independently of ABCA1
Int J Mol Sci, 24 (6)
DOI 10.3390/ijms24065992, PubMed 36983062
GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors
Am J Psychiatry, 180 (10), 723-738
DOI 10.1176/appi.ajp.21121266, PubMed 37777856
XCR1+ DCs are critical for T cell-mediated immunotherapy of chronic viral infections
Cell Rep, 42 (2), 112123 (in press)
DOI 10.1016/j.celrep.2023.112123, PubMed 36795562
Clinical significance of L1CAM expression in metastatic tubo-ovarian high-grade serous carcinoma
Gynecol Oncol, 176, 76-81
DOI 10.1016/j.ygyno.2023.07.004, PubMed 37478615
Molecular characteristics of low-grade serous carcinoma in effusions
Cytopathology, 34 (2), 99-105
DOI 10.1111/cyt.13207, PubMed 36609991
"Evaluation of ROS1 expression and rearrangements in a large cohort of early-stage lung cancer"
Diagn Pathol, 18 (1), 70
DOI 10.1186/s13000-023-01357-1, PubMed 37237384
Brain water content in sudden unexpected infant death
Forensic Sci Med Pathol (in press)
DOI 10.1007/s12024-023-00584-8, PubMed 36735187
Impact of KRAS and BRAF mutations on treatment efficacy and survival in high-grade gastroenteropancreatic neuroendocrine neoplasms
J Neuroendocrinol, 35 (4), e13256
DOI 10.1111/jne.13256, PubMed 37017614
Cross-Sectional Study Exploring Vision-related Quality of Life in Dry Eye Disease in a Norwegian Optometric Practice
Optom Vis Sci (in press)
DOI 10.1097/OPX.0000000000002058, PubMed 37751404
Photodynamic Effects with 5-Aminolevulinic Acid on Cytokines and Exosomes in Human Peripheral Blood Mononuclear Cells from Patients with Crohn's Disease
Int J Mol Sci, 24 (5)
DOI 10.3390/ijms24054554, PubMed 36901982
DNase analysed by a novel competitive assay in patients with complications after ChAdOx1 nCoV-19 vaccination and in normal unvaccinated blood donors
Scand J Immunol, 98 (1), e13274
DOI 10.1111/sji.13274, PubMed 37676118
Gene expression profiling of subcutaneous adipose tissue reveals new biomarkers in acromegaly
Eur J Endocrinol, 188 (3)
DOI 10.1093/ejendo/lvad031, PubMed 36895180
Physiological expression of mutated TAU impaired astrocyte activity and exacerbates β-amyloid pathology in 5xFAD mice
J Neuroinflammation, 20 (1), 174
DOI 10.1186/s12974-023-02823-9, PubMed 37496076
Robust spike-specific CD4+ and CD8+ T cell responses in SARS-CoV-2 vaccinated hematopoietic cell transplantation recipients: a prospective, cohort study
Front Immunol, 14, 1210899
DOI 10.3389/fimmu.2023.1210899, PubMed 37503339
Assessing developability early in the discovery process for novel biologics
MAbs, 15 (1), 2171248
DOI 10.1080/19420862.2023.2171248, PubMed 36823021
FANCM missense variants and breast cancer risk: a case-control association study of 75,156 European women
Eur J Hum Genet, 31 (5), 578-587
DOI 10.1038/s41431-022-01257-w, PubMed 36707629
Spectrum and Frequency of Germline FANCM Protein-Truncating Variants in 44,803 European Female Breast Cancer Cases
Cancers (Basel), 15 (13)
DOI 10.3390/cancers15133313, PubMed 37444426
Intense pulsed light treatment in meibomian gland dysfunction: Past, present, and future
Acta Ophthalmol (in press)
DOI 10.1111/aos.15759, PubMed 37702308
Rapid, Cost-Efficient, Enzyme-Free Passaging of Human Pluripotent Stem Cells on Feeder Cells by Ethylenediaminetetraacetic Acid-Mediated Dis-Adhesion
J Vis Exp (197)
DOI 10.3791/63788, PubMed 37486113
Purinergic 2X 4 (P2X4), but not P2X7, receptors increase cytosolic [Ca2+] and stimulate mucin secretion in rat conjunctival goblet cells to maintain ocular surface health
Exp Eye Res, 235, 109614
DOI 10.1016/j.exer.2023.109614, PubMed 37580003
Nausea Predicts Bacteremia in Immunocompetent Patients with Pneumococcal Community-Acquired Pneumonia: Secondary Data Analysis from a Prospective Cohort
J Clin Med, 12 (12)
DOI 10.3390/jcm12123924, PubMed 37373619
WT1 and PRAME RNA-loaded dendritic cell vaccine as maintenance therapy in de novo AML after intensive induction chemotherapy
Leukemia, 37 (9), 1842-1849
DOI 10.1038/s41375-023-01980-3, PubMed 37507426
A systematic safety pipeline for selection of T-cell receptors to enter clinical use
NPJ Vaccines, 8 (1), 126
DOI 10.1038/s41541-023-00713-y, PubMed 37607971
Shared genetic loci between Alzheimer's disease and multiple sclerosis: Crossroads between neurodegeneration and immune system
Neurobiol Dis, 183, 106174
DOI 10.1016/j.nbd.2023.106174, PubMed 37286172
OnTarget: in silico design of MiniPromoters for targeted delivery of expression
Nucleic Acids Res, 51 (W1), W379-W386
DOI 10.1093/nar/gkad375, PubMed 37166953
Comparison between articular chondrocytes and mesenchymal stromal cells for the production of articular cartilage implants
Front Bioeng Biotechnol, 11, 1116513
DOI 10.3389/fbioe.2023.1116513, PubMed 36896010
Complex interactions of cellular players in chronic Graft-versus-Host Disease
Front Immunol, 14, 1199422
DOI 10.3389/fimmu.2023.1199422, PubMed 37435079
Is a Single Nephrographic Phase Computed Tomography Sufficient for Detecting Urothelial Carcinoma in Patients with Visible Haematuria? A Prospective Paired Noninferiority Comparison
Eur Urol Open Sci, 55, 1-10
DOI 10.1016/j.euros.2023.06.005, PubMed 37693732
A single amino acid deletion in the ER Ca2+ sensor STIM1 reverses the in vitro and in vivo effects of the Stormorken syndrome-causing R304W mutation
Sci Signal, 16 (771), eadd0509
DOI 10.1126/scisignal.add0509, PubMed 36749824
In vitro evaluation of iron oxide nanoparticle-induced thromboinflammatory response using a combined human whole blood and endothelial cell model
Front Immunol, 14, 1101387
DOI 10.3389/fimmu.2023.1101387, PubMed 37081885
Longitudinal changes of serum cytokines in patients with chronic low back pain and Modic changes
Osteoarthritis Cartilage, 31 (4), 543-547
DOI 10.1016/j.joca.2023.01.001, PubMed 36640896
Crash-involved THC-positive drivers in Norway have a high frequency of polysubstance use
Drug Alcohol Depend, 244, 109800
DOI 10.1016/j.drugalcdep.2023.109800, PubMed 36774807
Prevalence of alcohol and drugs among drivers killed in road traffic crashes in Norway during 2011-2020
Traffic Inj Prev, 24 (3), 256-261
DOI 10.1080/15389588.2023.2174801, PubMed 36763459
Legal limits for driving under the influence of illicit drugs: large variations between jurisdictions
Forensic Sci Int Rep, 8, 100336
DOI 10.1016/j.fsir.2023.100336, PublikaID 443
Antibody blockade of Jagged1 attenuates choroidal neovascularization
Nat Commun, 14 (1), 3109
DOI 10.1038/s41467-023-38563-w, PubMed 37253747
Progressive mitochondrial dysfunction in cerebellar synaptosomes of cystatin B-deficient mice
Front Mol Neurosci, 16, 1175851
DOI 10.3389/fnmol.2023.1175851, PubMed 37251643
Linking Laboratory Testing to Clinical Outcomes: Bridging the Gap through Outcome-Based Studies in Laboratory Medicine
Clin Chem (in press)
DOI 10.1093/clinchem/hvad132, PubMed 37688514
Increased thromboinflammatory load in hereditary angioedema
Clin Exp Immunol (in press)
DOI 10.1093/cei/uxad091, PubMed 37561062
High plasma levels of C1-inhibitor are associated with lower risk of future venous thromboembolism
J Thromb Haemost, 21 (7), 1849-1860
DOI 10.1016/j.jtha.2023.03.024, PubMed 37003465
Prevalence of Dry Eye Disease Among Individuals Scheduled for Cataract Surgery in a Norwegian Cataract Clinic
Clin Ophthalmol, 17, 1233-1243
DOI 10.2147/OPTH.S407805, PubMed 37138823
The Histopathology of Cold Agglutinin Disease-Associated B-Cell Lymphoproliferative Disease
Am J Clin Pathol, 160 (3), 229-237
DOI 10.1093/ajcp/aqad048, PubMed 37253147
Restraint stress during neonatal hypoxia-ischemia alters brain injury following normothermia and hypothermia
Physiol Rep, 11 (1), e15562
DOI 10.14814/phy2.15562, PubMed 36636750
Sex-specific microglia state in the Neuroligin-4 knock-out mouse model of autism spectrum disorder
Brain Behav Immun, 111, 61-75
DOI 10.1016/j.bbi.2023.03.023, PubMed 37001827
[Not Available]
Tidsskr Nor Laegeforen, 143 (13)
DOI 10.4045/tidsskr.23.0482, PubMed 37753769
Nucleated red blood cells explain most of the association between DNA methylation and gestational age
Commun Biol, 6 (1), 224
DOI 10.1038/s42003-023-04584-w, PubMed 36849614
Spatial cumulant models enable spatially informed treatment strategies and analysis of local interactions in cancer systems
J Math Biol, 86 (5), 68
DOI 10.1007/s00285-023-01903-x, PubMed 37017776
In vitro and ex vivo proteomics of Mycobacterium marinum biofilms and the development of biofilm-binding synthetic nanobodies
mSystems, 8 (3), e0107322
DOI 10.1128/msystems.01073-22, PubMed 37184670
Associations between psychiatric comorbid disorders and executive dysfunctions in hypocretin-1 deficient pediatric narcolepsy type1
Sleep Med, 109, 149-157
DOI 10.1016/j.sleep.2023.06.021, PubMed 37442017
Scalable production of tissue-like vascularized liver organoids from human PSCs
Exp Mol Med (in press)
DOI 10.1038/s12276-023-01074-1, PubMed 37653039
Middle-Aged and Older Patients With Left Ventricular Hypertrophy: Higher Mortality With Drug Treated Systolic Blood Pressure Below 130 mm Hg
Hypertension, 80 (8), 1739-1748
DOI 10.1161/HYPERTENSIONAHA.123.21454, PubMed 37350267
Multimodal human thymic profiling reveals trajectories and cellular milieu for T agonist selection
Front Immunol, 13, 1092028
DOI 10.3389/fimmu.2022.1092028, PubMed 36741401
A tumor microenvironment model of chronic lymphocytic leukemia enables drug sensitivity testing to guide precision medicine
Cell Death Discov, 9 (1), 125
DOI 10.1038/s41420-023-01426-w, PubMed 37055391
siRNA screening reveals that SNAP29 contributes to exosome release
Cell Mol Life Sci, 80 (7), 177
DOI 10.1007/s00018-023-04822-8, PubMed 37285022
Report on 4 cases with decreased recovery due to neutralizing antibodies specific for PEGylated recombinant factor VIII
J Thromb Haemost, 21 (10), 2771-2775
DOI 10.1016/j.jtha.2023.07.019, PubMed 37543216
Ex Vivo Pig Eye Model for Studying Diffusion of Acylcarnitines with Different Physicochemical Properties
J Ocul Pharmacol Ther, 39 (5), 324-331
DOI 10.1089/jop.2022.0159, PubMed 37219540
Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders
Psychoneuroendocrinology, 157, 106368
DOI 10.1016/j.psyneuen.2023.106368, PubMed 37659117
Multivariate genetic analysis of personality and cognitive traits reveals abundant pleiotropy
Nat Hum Behav, 7 (9), 1584-1600
DOI 10.1038/s41562-023-01630-9, PubMed 37365406
Impulsivity across severe mental disorders: a cross-sectional study of immune markers and psychopharmacotherapy
BMC Psychiatry, 23 (1), 659
DOI 10.1186/s12888-023-05154-4, PubMed 37674162
A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation
Hepatology, 77 (3), 715-728
DOI 10.1002/hep.32773, PubMed 36056902
Genome-wide analyses reveal novel opioid use disorder loci and genetic overlap with schizophrenia, bipolar disorder, and major depression
Addict Biol, 28 (6), e13282
DOI 10.1111/adb.13282, PubMed 37252880
Bidirectional genetic overlap between autism spectrum disorder and cognitive traits
Transl Psychiatry, 13 (1), 295
DOI 10.1038/s41398-023-02563-7, PubMed 37709755
Humoral vaccine response and breakthrough infections in kidney transplant recipients during the COVID-19 pandemic: a nationwide cohort study
EClinicalMedicine, 60, 102035
DOI 10.1016/j.eclinm.2023.102035, PubMed 37362086
Functional Analyses of Rare Germline Missense BRCA1 Variants Located within and outside Protein Domains with Known Functions
Genes (Basel), 14 (2)
DOI 10.3390/genes14020262, PubMed 36833189
Circulating tumour DNA alterations: emerging biomarker in head and neck squamous cell carcinoma
J Biomed Sci, 30 (1), 65
DOI 10.1186/s12929-023-00953-z, PubMed 37559138
Functional SARS-CoV-2 cross-reactive CD4+ T cells established in early childhood decline with age
Proc Natl Acad Sci U S A, 120 (12), e2220320120
DOI 10.1073/pnas.2220320120, PubMed 36917669
A comparison between hyaluronic acid and other single ingredient eye drops for dry eye, a review
Acta Ophthalmol (in press)
DOI 10.1111/aos.15675, PubMed 37042308
Quantitative PCR analysis of bloodstains of different ages
Forensic Sci Int, 350, 111785
DOI 10.1016/j.forsciint.2023.111785, PubMed 37527614
Rise and fall of SARS-CoV-2 variants in Rotterdam: Comparison of wastewater and clinical surveillance
Sci Total Environ, 873, 162209
DOI 10.1016/j.scitotenv.2023.162209, PubMed 36796689
Genome-wide Association Analysis of Schizophrenia and Vitamin D Levels Shows Shared Genetic Architecture and Identifies Novel Risk Loci
Schizophr Bull (in press)
DOI 10.1093/schbul/sbad063, PubMed 37163672
Associations Between Symptoms of Premenstrual Disorders and Polygenic Liability for Major Psychiatric Disorders
JAMA Psychiatry, 80 (7), 738-742
DOI 10.1001/jamapsychiatry.2023.1137, PubMed 37163253
The spectrum of pyridoxine dependent epilepsy across the age span: A nationwide retrospective observational study
Epilepsy Res, 190, 107099
DOI 10.1016/j.eplepsyres.2023.107099, PubMed 36731270
Elevated Systemic Levels of Markers Reflecting Intestinal Barrier Dysfunction and Inflammasome Activation Are Correlated in Severe Mental Illness
Schizophr Bull, 49 (3), 635-645
DOI 10.1093/schbul/sbac191, PubMed 36462169
GWAS on retinal vasculometry phenotypes
PLoS Genet, 19 (2), e1010583
DOI 10.1371/journal.pgen.1010583, PubMed 36757925
Human cytomegalovirus infection perturbs neural progenitor cell fate via the expression of viral microRNAs
J Med Virol, 95 (2), e28574
DOI 10.1002/jmv.28574, PubMed 36772841
A Comparison of Risk Classification Systems of Colorectal Adenomas: A Case-Cohort Study
Gastroenterology, 165 (2), 483-491.e7
DOI 10.1053/j.gastro.2023.04.028, PubMed 37146913
Pharmacological aspects of antiseizure medications: From basic mechanisms to clinical considerations of drug interactions and use of therapeutic drug monitoring
Epileptic Disord, 25 (4), 454-471
DOI 10.1002/epd2.20069, PubMed 37259844
Body Fluid Identification in Samples Collected after Intimate and Social Contact: A Comparison of Two mRNA Profiling Methods and the Additional Information Gained by cSNP Genotypes
Genes (Basel), 14 (3)
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Safe Blood Donation from Donors Using Antihypertensive Medication. A Multi-Center Retrospective Quality Study from South-East Norway
J Blood Med, 14, 337-343
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A preclinical model to investigate normal tissue damage following fractionated radiotherapy to the head and neck
J Radiat Res, 64 (1), 44-52
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Larger hypothalamic volume in narcolepsy type 1
Sleep (in press)
DOI 10.1093/sleep/zsad173, PubMed 37463428
Adalimumab serum levels and anti-drug antibodies: associations to treatment response and drug survival in inflammatory joint diseases
Rheumatology (Oxford) (in press)
DOI 10.1093/rheumatology/kead525, PubMed 37773994
Humoral immune response to SARS-CoV-2 vaccination in patients with inflammatory bowel disease on immunosuppressive medication: association to serum drug levels and disease type
Scand J Gastroenterol, 58 (8), 874-882
DOI 10.1080/00365521.2023.2177884, PubMed 36788656
Towards optimised extracellular vesicle proteomics from cerebrospinal fluid
Sci Rep, 13 (1), 9564
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Identification of novel genomic risk loci shared between common epilepsies and psychiatric disorders
Brain, 146 (8), 3392-3403
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Toward real-world automated antibody design with combinatorial Bayesian optimization
Cell Rep Methods, 3 (1), 100374
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EMD originates from hyaluronan-induced homophilic interactions of CD44 variant-expressing MM cells under shear stress
Blood Adv, 7 (4), 508-524
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Kidney-transplanted Adolescents-Nonadherence and Graft Outcomes During the Transition Phase: A Nationwide Analysis, 2000-2020
Transplantation, 107 (5), 1206-1212
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Mutation Spectrum in Liquid Versus Solid Biopsies From Patients With Advanced Gastroenteropancreatic Neuroendocrine Carcinoma
JCO Precis Oncol, 7, e2200336
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Association of pro-inflammatory cytokines with trauma and post-traumatic stress disorder visiting a tertiary care hospital in Kathmandu
PLoS One, 18 (2), e0281125
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Impact of glaucoma medications on the ocular surface and how ocular surface disease can influence glaucoma treatment
Ocul Surf, 29, 456-468
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TGFBR3L is associated with gonadotropin production in non-functioning gonadotroph pituitary neuroendocrine tumours
Pituitary, 26 (2), 227-236
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Rare CNVs and phenome-wide profiling highlight brain structural divergence and phenotypical convergence
Nat Hum Behav, 7 (6), 1001-1017
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Vasa, Piwi, and Pl10 Expression during Sexual Maturation and Asexual Reproduction in the Annelid Pristina longiseta
J Dev Biol, 11 (3)
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SENP2 knockdown in human adipocytes reduces glucose metabolism and lipid accumulation, while increases lipid oxidation
Metabol Open, 18, 100234
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Comparative Evaluation of Carboxyhemoglobin Quantification in Postmortem Whole Blood by CO-Oximetry and Headspace Gas Chromatography with Flame Ionization Detection and Atom Absorption Spectrophotometry
J Anal Toxicol, 47 (3), 311-316
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Subcortical Brain Alterations in Carriers of Genomic Copy Number Variants
Am J Psychiatry, 180 (9), 685-698
DOI 10.1176/appi.ajp.20220304, PubMed 37434504
Intraindividual Variability in Absolute Bioavailability and Clearance of Midazolam in Healthy Individuals
Clin Pharmacokinet, 62 (7), 981-987
DOI 10.1007/s40262-023-01257-z, PubMed 37162619
Characterization of Mechanical and Cellular Effects of Rhythmic Vertical Vibrations on Adherent Cell Cultures
Bioengineering (Basel), 10 (7)
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Mass spectrometry reveals that oxysterols are secreted from non-alcoholic fatty liver disease induced organoids
J Steroid Biochem Mol Biol, 232, 106355
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Quantitative chemometric phenotyping of three-dimensional liver organoids by Raman spectral imaging
Cell Rep Methods, 3 (4), 100440
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Atorvastatin Metabolite Pattern in Skeletal Muscle and Blood from Patients with Coronary Heart Disease and Statin-Associated Muscle Symptoms
Clin Pharmacol Ther, 113 (4), 887-895
DOI 10.1002/cpt.2844, PubMed 36622792
Comparative basal transcriptome profiles of the olfactory rosette and gills of Atlantic salmon (Salmo salar) unveil shared and distinct immunological features
Genomics, 115 (3), 110632
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TiSA: TimeSeriesAnalysis-a pipeline for the analysis of longitudinal transcriptomics data
NAR Genom Bioinform, 5 (1), lqad020
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Characterization and clinical impact of the tumor microenvironment in post-transplant aggressive B-cell lymphomas
Haematologica (in press)
DOI 10.3324/haematol.2023.282831, PubMed 37259566
Therapeutic Drug Monitoring and Dosage Adjustments of Immunosuppressive Drugs When Combined With Nirmatrelvir/Ritonavir in Patients With COVID-19
Ther Drug Monit, 45 (2), 191-199
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MGMT methylation pattern of long-term and short-term survivors of glioblastoma reveals CpGs of the enhancer region to be of high prognostic value
Acta Neuropathol Commun, 11 (1), 139
DOI 10.1186/s40478-023-01622-w, PubMed 37641156
Evaluation of European-based polygenic risk score for breast cancer in Ashkenazi Jewish women in Israel
J Med Genet (in press)
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Analysis of Spatial Molecular Data
Methods Mol Biol, 2614, 349-356
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Can acetate via FFA receptors contribute to the diabetogenic effect of statins?
Naunyn Schmiedebergs Arch Pharmacol (in press)
DOI 10.1007/s00210-023-02647-7, PubMed 37642662
Single-cell m6A mapping in vivo using picoMeRIP-seq
Nat Biotechnol (in press)
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A loss-of-function mutation in human Oxidation Resistance 1 disrupts the spatial-temporal regulation of histone arginine methylation in neurodevelopment
Genome Biol, 24 (1), 216
DOI 10.1186/s13059-023-03037-1, PubMed 37773136
DNA Glycosylases Define the Outcome of Endogenous Base Modifications
Int J Mol Sci, 24 (12)
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Disruption of the sialic acid/Siglec-9 axis improves antibody-mediated neutrophil cytotoxicity towards tumor cells
Front Immunol, 14, 1178817
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Anti-Inflammatory and Pro-resolving Actions of the N-Terminal Peptides Ac2-26, Ac2-12, and Ac9-25 of Annexin A1 on Conjunctival Goblet Cell Function
Am J Pathol (in press)
DOI 10.1016/j.ajpath.2023.05.020, PubMed 37423551
Late-onset sensory-motor axonal neuropathy, a novel SLC12A6-related phenotype
Brain, 146 (3), 912-922
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Gene Regulatory Interactions at Lamina-Associated Domains
Genes (Basel), 14 (2)
DOI 10.3390/genes14020334, PubMed 36833261
Assessing IgE sensitization profiles to birch and timothy grass pollen allergens in birch pollen allergic blood donors using an oligoplex specific IgE assay
Scand J Clin Lab Invest, 1-4 (in press)
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[11C]metoclopramide is a sensitive radiotracer to measure moderate decreases in P-glycoprotein function at the blood-brain barrier
J Cereb Blood Flow Metab, 271678X231202336 (in press)
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Associations between Serial Intravitreal Injections and Dry Eye
Ophthalmology, 130 (5), 509-515
DOI 10.1016/j.ophtha.2023.01.009, PubMed 36693594
MicroRNA-143-5p Suppresses ER-Positive Breast Cancer Development by Targeting Oncogenic HMGA2
Clin Breast Cancer, 23 (7), e480-e490.e3
DOI 10.1016/j.clbc.2023.07.011, PubMed 37596147
Genome-wide association study of hemolytic uremic syndrome causing Shiga toxin-producing Escherichia coli from Sweden, 1994-2018
Eur J Clin Microbiol Infect Dis, 42 (6), 771-779
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Bone mineral density loci specific to the skull portray potential pleiotropic effects on craniosynostosis
Commun Biol, 6 (1), 691
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Preclinical Evaluation of a 64Cu-Based Theranostic Approach in a Murine Model of Multiple Myeloma
Pharmaceutics, 15 (7)
DOI 10.3390/pharmaceutics15071817, PubMed 37514004
Prevalent and immunodominant CD8 T cell epitopes are conserved in SARS-CoV-2 variants
Cell Rep, 42 (1), 111995
DOI 10.1016/j.celrep.2023.111995, PubMed 36656713
Effects of storage on quality and function of acid-treated platelets with reduced HLA Class I surface expression
Transfus Med, 33 (4), 329-336
DOI 10.1111/tme.12983, PubMed 37356816
A homozygous POLR1A variant causes leukodystrophy and affects protein homeostasis
Brain, 146 (8), 3513-3527
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Telomere length and verbal learning in bipolar disorders
J Affect Disord, 339, 555-560
DOI 10.1016/j.jad.2023.07.087, PubMed 37459977
MRI Assessment of Changes in Tumor Vascularization during Neoadjuvant Anti-Angiogenic Treatment in Locally Advanced Breast Cancer Patients
Cancers (Basel), 15 (18)
DOI 10.3390/cancers15184662, PubMed 37760629
Stress biomarkers in adult patients with drug-resistant epilepsy on a modified Atkins diet: A prospective study
Epilepsia Open (in press)
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The impact of coding germline variants on contralateral breast cancer risk and survival
Am J Hum Genet, 110 (3), 475-486
DOI 10.1016/j.ajhg.2023.02.003, PubMed 36827971
Association of the CHEK2 c.1100delC variant, radiotherapy, and systemic treatment with contralateral breast cancer risk and breast cancer-specific survival
Cancer Med, 12 (15), 16142-16162
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The work-related burden of dry eye
Ocul Surf, 28, 30-36
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Improved computations for relationship inference using low-coverage sequencing data
BMC Bioinformatics, 24 (1), 90
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Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry
Genome Med, 15 (1), 7
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Cytosolic antibody receptor TRIM21 is required for effective tau immunotherapy in mouse models
Science, 379 (6639), 1336-1341
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Osteocyte-Like Cells Differentiated From Primary Osteoblasts in an Artificial Human Bone Tissue Model
JBMR Plus, 7 (9), e10792
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PREDICT validity for prognosis of breast cancer patients with pathogenic BRCA1/2 variants
NPJ Breast Cancer, 9 (1), 37
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Circulating markers of extracellular matrix remodelling in severe COVID-19 patients
J Intern Med (in press)
DOI 10.1111/joim.13725, PubMed 37718572
Anterior blepharitis is associated with elevated plectin levels consistent with a pronounced intracellular response
Ocul Surf, 29, 444-455
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ABC Transporter C1 Prevents Dimethyl Fumarate from Targeting Alzheimer's Disease
Biology (Basel), 12 (7)
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H2S-Enriched Flush out Does Not Increase Donor Organ Quality in a Porcine Kidney Perfusion Model
Antioxidants (Basel), 12 (3)
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Hemicolectomy versus appendectomy for patients with appendiceal neuroendocrine tumours 1-2 cm in size: a retrospective, Europe-wide, pooled cohort study
Lancet Oncol, 24 (2), 187-194
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The relationship between sedentary behavior and dry eye disease
Ocul Surf, 28, 11-17
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The Significance of Inter-Eye Osmolarity Difference in Dry Eye Diagnostics
Clin Ophthalmol, 17, 829-835
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COVID-19 patients treated with convalescent plasma
Tidsskr Nor Laegeforen, 143 (11)
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Convalescent plasma from Norwegian blood donors to treat COVID-19
Tidsskr Nor Laegeforen, 143 (11)
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Clinical efficacy of buprenorphine after oral dosing in rats undergoing major surgery
Lab Anim, 236772231178417 (in press)
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High-throughput screen in vitro identifies dasatinib as a candidate for combinatorial treatment with HER2-targeting drugs in breast cancer
PLoS One, 18 (1), e0280507
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A PRRX1 Signature Identifies TIM-3 and VISTA as Potential Immune Checkpoint Targets in a Subgroup of Microsatellite Stable Colorectal Cancer Liver Metastases
Cancer Res Commun, 3 (2), 235-244
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Polygenic overlap with body-mass index improves prediction of treatment-resistant schizophrenia
Psychiatry Res, 325, 115217
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Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality
Nat Commun, 14 (1), 3453
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Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy
Nat Commun, 14 (1), 2709
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Simultaneous LC-MS determination of glucose regulatory peptides secreted by stem cell-derived islet organoids
Electrophoresis (in press)
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No impact of prenatal paracetamol and folic acid exposure on cord blood DNA methylation in children with attention-deficit/hyperactivity disorder
Front Genet, 14, 1204879
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Effects of prenatal exposure to (es)citalopram and maternal depression during pregnancy on DNA methylation and child neurodevelopment
Transl Psychiatry, 13 (1), 149
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Hepcidin analysis in pneumonia: Comparison of immunoassay and LC-MS/MS
Ann Clin Biochem, 45632231159529 (in press)
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Transcriptional and functional effects of lithium in bipolar disorder iPSC-derived cortical spheroids
Mol Psychiatry (in press)
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Therapeutic Salivary Monitoring of Perampanel in Patients with Epilepsy Using a Volumetric Absorptive Microsampling Technique
Pharmaceutics, 15 (8)
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Genetic Pathways in Peritoneal Mesothelioma Tumorigenesis
Cancer Genomics Proteomics, 20 (4), 363-374
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Fusion of the High-mobility Group AT-Hook 2 (HMGA2) and the Gelsolin (GSN) Genes in Lipomas With t(9;12)(q33;q14) Chromosomal Translocation
In Vivo, 37 (2), 524-530
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Chromosome Translocation t(10;19)(q26;q13) in a CIC-sarcoma
In Vivo, 37 (1), 57-69
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Recurrent 8q11-13 Aberrations Leading to PLAG1 Rearrangements, Including Novel Chimeras HNRNPA2B1::PLAG1 and SDCBP::PLAG1, in Lipomatous Tumors
Cancer Genomics Proteomics, 20 (2), 171-181
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Genetic Overlap Between Global Cortical Brain Structure, C-Reactive Protein, and White Blood Cell Counts
Biol Psychiatry (in press)
DOI 10.1016/j.biopsych.2023.06.008, PubMed 37348803
Psychiatric disorders and brain white matter exhibit genetic overlap implicating developmental and neural cell biology
Mol Psychiatry (in press)
DOI 10.1038/s41380-023-02264-z, PubMed 37759039
Decreased serum concentrations of antiseizure medications in children with drug resistant epilepsy following treatment with ketogenic diet
Epilepsia Open, 8 (3), 858-866
DOI 10.1002/epi4.12746, PubMed 37057954
Injuries associated with mechanical chest compressions and active decompressions after out-of-hospital cardiac arrest: A subgroup analysis of non-survivors from a randomized study
Resusc Plus, 13, 100362
DOI 10.1016/j.resplu.2023.100362, PubMed 36798487
Ghrelin is related to lower brain reward activation during touch
Psychophysiology, e14443 (in press)
DOI 10.1111/psyp.14443, PubMed 37737514
Single-cell transcriptomics combined with proteomics of intrathecal IgG reveal transcriptional heterogeneity of oligoclonal IgG-secreting cells in multiple sclerosis
Front Cell Neurosci, 17, 1189709
DOI 10.3389/fncel.2023.1189709, PubMed 37362001
Machine learning-based immune phenotypes correlate with STK11/KEAP1 co-mutations and prognosis in resectable NSCLC: a sub-study of the TNM-I trial
Ann Oncol, 34 (7), 578-588
DOI 10.1016/j.annonc.2023.04.005, PubMed 37100205
Maintaining transcriptional homeostasis during cell cycle
Transcription, 1-21 (in press)
DOI 10.1080/21541264.2023.2246868, PubMed 37655806
Mitotic chromosome condensation resets chromatin to safeguard transcriptional homeostasis during interphase
Proc Natl Acad Sci U S A, 120 (4), e2210593120
DOI 10.1073/pnas.2210593120, PubMed 36656860
Defining and Studying B Cell Receptor and TCR Interactions
J Immunol, 211 (3), 311-322
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A Transcriptomic Appreciation of Childhood Meningococcal and Polymicrobial Sepsis from a Pro-inflammatory and Trajectorial Perspective, a Role for VEGF-A and VEGF-B Modulation?
Shock (in press)
DOI 10.1097/SHK.0000000000002192, PubMed 37553892
Alpha-B-Crystallin overexpression is sufficient to promote tumorigenesis and metastasis in mice
Exp Hematol Oncol, 12 (1), 4
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A fast, low-cost, robust and high-throughput method for viral nucleic acid isolation based on NAxtra magnetic nanoparticles
Sci Rep, 13 (1), 11714
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Determinants of humoral and cellular immune responses to three doses of mRNA SARS-CoV-2 vaccines in older adults: a longitudinal cohort study
Lancet Healthy Longev, 4 (5), e188-e199
DOI 10.1016/S2666-7568(23)00055-7, PubMed 37148891
Safety of hypoxic red blood cell administration in patients with transfusion-dependent hematological malignancies: An interim analysis
Transfus Apher Sci, 103755 (in press)
DOI 10.1016/j.transci.2023.103755, PubMed 37423867
Identification of Mycobacterium abscessus Subspecies by MALDI-TOF Mass Spectrometry and Machine Learning
J Clin Microbiol, 61 (1), e0111022
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AXIN2-related oligodontia-colorectal cancer syndrome with cleft palate as a possible new feature
Mol Genet Genomic Med, 11 (6), e2157
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The X-factor in ART: does the use of assisted reproductive technologies influence DNA methylation on the X chromosome?
Hum Genomics, 17 (1), 35
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Fipronil affects cockroach behavior and olfactory memory
J Exp Biol, 226 (8)
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Thromboinflammatory response is increased in pancreas transplant alone versus simultaneous pancreas-kidney transplantation and early pancreas graft thrombosis is associated with complement activation
Front Immunol, 14, 1044444
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Small extracellular vesicles have distinct CD81 and CD9 tetraspanin expression profiles in plasma from rheumatoid arthritis patients
Clin Exp Med, 23 (6), 2867-2875
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Characterizing the Shared Genetic Underpinnings of Schizophrenia and Cardiovascular Disease Risk Factors
Am J Psychiatry, appiajp20220660 (in press)
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Renal function, sex and age influence purines and pyrimidines in urine and could lead to diagnostic misinterpretation
Mol Genet Metab, 140 (3), 107649 (in press)
DOI 10.1016/j.ymgme.2023.107649, PubMed 37517327
Increased Sphingomyelin and Free Sialic Acid in Cerebrospinal Fluid of Kearns-Sayre Syndrome: New Findings Using Untargeted Metabolomics
Pediatr Neurol, 143, 68-76
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Plasma Inflammatory Biomarkers Are Associated With Poststroke Cognitive Impairment: The Nor-COAST Study
Stroke, 54 (5), 1303-1311
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Design, Synthesis, and Evaluation of Novel Δ2-Thiazolino 2-Pyridone Derivatives That Potentiate Isoniazid Activity in an Isoniazid-Resistant Mycobacterium tuberculosis Mutant
J Med Chem, 66 (16), 11056-11077
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The expanding organelle lipidomes: current knowledge and challenges
Cell Mol Life Sci, 80 (8), 237
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Subtypes of high-grade breast ductal carcinoma in situ (DCIS): incidence and potential clinical impact
Breast Cancer Res Treat, 201 (2), 329-338
DOI 10.1007/s10549-023-07016-9, PubMed 37453021
Mitochondria hormesis delays aging and associated diseases in Caenorhabditis elegans impacting on key ferroptosis players
iScience, 26 (4), 106448
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LDL cholesterol targets rarely achieved in familial hypercholesterolemia patients: A sex and gender-specific analysis
Atherosclerosis (in press)
DOI 10.1016/j.atherosclerosis.2023.03.022, PubMed 37080805
High-throughput quantification of emerging ''nitazene'' benzimidazole opioid analogs by microextraction and UHPLC-MS/MS
J Anal Toxicol (in press)
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Prevalence and Characteristics Associated With Post-COVID-19 Condition Among Nonhospitalized Adolescents and Young Adults
JAMA Netw Open, 6 (3), e235763
DOI 10.1001/jamanetworkopen.2023.5763, PubMed 36995712
Cortactin expression in a Norwegian cohort of human papilloma virus negative oral squamous cell carcinomas of the mobile tongue
Eur J Oral Sci, 131 (2), e12925
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A role for the terminal C5-C9 complement pathway in idiopathic pulmonary fibrosis
Front Med (Lausanne), 10, 1236495
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Clusters of healthcare-associated SARS-CoV-2 infections in Norwegian hospitals detected by a fully automatic register-based surveillance system
J Hosp Infect, 135, 50-54
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Prostate cancer radiogenomics reveals proliferative gene expression programs associated with distinct MRI-based hypoxia levels
Radiother Oncol, 188, 109875 (in press)
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Complement factors B, D, C3bBbP and risk of future venous thromboembolism
Clin Immunol, 249, 109278
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Disruption of Phosphodiesterase 3A Binding to SERCA2 Increases SERCA2 Activity and Reduces Mortality in Mice With Chronic Heart Failure
Circulation, 147 (16), 1221-1236
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Dried blood spot analysis with liquid chromatography and mass spectrometry: Trends in clinical chemistry
J Sep Sci, 46 (15), e2300210
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Conductive vial electromembrane extraction of opioids from oral fluid
Anal Bioanal Chem, 415 (22), 5323-5335
DOI 10.1007/s00216-023-04807-3, PubMed 37386201
Determination of amphetamine enantiomers in urine by conductive vial electromembrane extraction and ultra-high performance supercritical fluid chromatography tandem mass spectrometry
Drug Test Anal, 15 (8), 909-918
DOI 10.1002/dta.3487, PubMed 37114617
Targeted Central Nervous System Irradiation with Proton Microbeam Induces Mitochondrial Changes in Caenorhabditis elegans
Biology (Basel), 12 (6)
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Effect of CYP2D6 and CYP2C19 genotypes on atomoxetine serum levels: A study based on therapeutic drug monitoring data
Br J Clin Pharmacol, 89 (7), 2246-2253
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Navigation-Assisted Surgery for Locally Advanced Primary and Recurrent Rectal Cancer
Ann Surg Oncol (in press)
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ASO Visual Abstract: Navigation-Assisted Surgery for Locally Advanced Primary and Recurrent Rectal Cancer
Ann Surg Oncol (in press)
DOI 10.1245/s10434-023-14105-y, PubMed 37589802
Impact of age, sex and cytochrome P450 genotype on quetiapine and N-desalkylquetiapine serum concentrations: A study based on real-world data from 8118 patients
Br J Clin Pharmacol (in press)
DOI 10.1111/bcp.15849, PubMed 37438870
Inflammatory markers and pulmonary function in adolescents and young adults 6 months after mild COVID-19
Front Immunol, 13, 1081718
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Diversity of intratumoral regulatory T cells in B-cell non-Hodgkin lymphoma
Blood Adv (in press)
DOI 10.1182/bloodadvances.2023010158, PubMed 37695745
Multi-omics approach reveals dysregulated genes during hESCs neuronal differentiation exposure to paracetamol
iScience, 26 (10), 107755
DOI 10.1016/j.isci.2023.107755, PubMed 37731623
A convolutional neural network STIFMap reveals associations between stromal stiffness and EMT in breast cancer
Nat Commun, 14 (1), 3561
DOI 10.1038/s41467-023-39085-1, PubMed 37322009
Profiling Cellular Ecosystems at Single-Cell Resolution and at Scale with EcoTyper
Methods Mol Biol, 2629, 43-71
DOI 10.1007/978-1-0716-2986-4_4, PubMed 36929073
Shared Genetic Loci Between Schizophrenia and White Blood Cell Counts Suggest Genetically Determined Systemic Immune Abnormalities
Schizophr Bull, 49 (5), 1345-1354
DOI 10.1093/schbul/sbad082, PubMed 37319439
Terminating routine cord blood RhD typing of the newborns to guide postnatal anti-D immunoglobulin prophylaxis based on the results of fetal RHD genotyping
Fetal Diagn Ther (in press)
DOI 10.1159/000531694, PubMed 37379821
Effects of faecal microbiota transplantation on the small intestinal mucosa in systemic sclerosis
Rheumatology (Oxford), 62 (8), 2918-2929
DOI 10.1093/rheumatology/kead014, PubMed 36688692
Driving under the influence of zopiclone: Elimination between two consecutive blood samples
Forensic Sci Int, 349, 111764
DOI 10.1016/j.forsciint.2023.111764, PubMed 37352736
Nystagmus among suspected amphetamine impaired drivers
J Forensic Leg Med, 95, 102502
DOI 10.1016/j.jflm.2023.102502, PubMed 36924680
Missense mutation Q384K in the APOB gene affecting the large lipid transfer module of apoB reduces the secretion of apoB-100 in the liver without reducing the secretion of apoB-48 in the intestine
J Clin Lipidol (in press)
DOI 10.1016/j.jacl.2023.08.009, PubMed 37718180
Contrast Enhanced Magnetic Resonance Imaging of Amyloid-β Plaques in a Murine Alzheimer's Disease Model
J Alzheimers Dis, 93 (2), 411-419
DOI 10.3233/JAD-220198, PubMed 37038807
Plasma concentration of atorvastatin metabolites correlates with low-density lipoprotein cholesterol reduction in patients with coronary heart disease
Pharmacol Res Perspect, 11 (3), e01089
DOI 10.1002/prp2.1089, PubMed 37186070
Multi-parametric MRI without artificial erection for preoperative assessment of primary penile carcinoma: A pilot study on the correlation between imaging and histopathological findings
Eur J Radiol Open, 10, 100478
DOI 10.1016/j.ejro.2023.100478, PubMed 36793771
Optimization of the Hemolysis Assay for the Assessment of Cytotoxicity
Int J Mol Sci, 24 (3)
DOI 10.3390/ijms24032914, PubMed 36769243
Psychosocial working conditions and sickness absence among younger employees in Denmark: a register-based cohort study using job exposure matrices
Scand J Work Environ Health, 49 (4), 249-258
DOI 10.5271/sjweh.4083, PubMed 36871249
BCKDK deficiency: a treatable neurodevelopmental disease amenable to newborn screening
Brain, 146 (7), 3003-3013
DOI 10.1093/brain/awad010, PubMed 36729635
Fasting and non-fasting plasma levels of monomethyl branched chain fatty acids: Implications for maple syrup urine disease
JIMD Rep, 64 (5), 360-366
DOI 10.1002/jmd2.12380, PubMed 37701324
Vitamin B12 Deficiency (Un-)Detected Using Newborn Screening in Norway
Int J Neonatal Screen, 9 (1)
DOI 10.3390/ijns9010003, PubMed 36648770
Shared genetic architecture between irritable bowel syndrome and psychiatric disorders reveals molecular pathways of the gut-brain axis
Genome Med, 15 (1), 60
DOI 10.1186/s13073-023-01212-4, PubMed 37528461
Oxycodone, Morphine, and Fentanyl in Patients With Chronic Pain: Proposal of Dose-Specific Concentration Ranges
Ther Drug Monit (in press)
DOI 10.1097/FTD.0000000000001112, PubMed 37296504
Survival of Escherichia coli after high-antibiotic stress is dependent on both the pregrown physiological state and incubation conditions
Front Microbiol, 14, 1149978
DOI 10.3389/fmicb.2023.1149978, PubMed 36970700
Effect of Intraperitoneal 224Radium-Labelled Microparticles on Compartmentalized Inflammation After Cytoreductive Surgery and Hypertherm Intraperitoneal Chemotherapy
Technol Cancer Res Treat, 22, 15330338231192902
DOI 10.1177/15330338231192902, PubMed 37574949
Design and preclinical testing of an anti-CD41 CAR T cell for the treatment of acute megakaryoblastic leukaemia
J Cell Mol Med, 27 (19), 2864-2875
DOI 10.1111/jcmm.17810, PubMed 37667538
RNA sequencing suggests that non-coding RNAs play a role in the development of acquired haemophilia
J Cell Mol Med, 27 (13), 1790-1796
DOI 10.1111/jcmm.17741, PubMed 37317065
Pathology and Molecular Biology of Melanoma
Curr Issues Mol Biol, 45 (7), 5575-5597
DOI 10.3390/cimb45070352, PubMed 37504268
The Glioblastoma CircularRNAome
International Journal of Molecular Sciences, 2023 (24(19)), 14545
DOI 10.3390/ijms241914545, PublikaID 444
Early response evaluation by single cell signaling profiling in acute myeloid leukemia
Nat Commun, 14 (1), 115
DOI 10.1038/s41467-022-35624-4, PubMed 36611026
Trimeric, APC-Targeted Subunit Vaccines Protect Mice against Seasonal and Pandemic Influenza
J Virol, 97 (2), e0169422
DOI 10.1128/jvi.01694-22, PubMed 36719241
Patients with schizophrenia and bipolar disorder display a similar global gene expression signature in whole blood that reflects elevated proportion of immature neutrophil cells with association to lipid changes
Transl Psychiatry, 13 (1), 147
DOI 10.1038/s41398-023-02442-1, PubMed 37147304
Efficacy and safety of baricitinib in hospitalized adults with severe or critical COVID-19 (Bari-SolidAct): a randomised, double-blind, placebo-controlled phase 3 trial
Crit Care, 27 (1), 9
DOI 10.1186/s13054-022-04205-8, PubMed 36627655
Gut microbiota composition during hospitalization is associated with 60-day mortality after severe COVID-19
Crit Care, 27 (1), 69
DOI 10.1186/s13054-023-04356-2, PubMed 36814280
An open chat with…Simon Rayner
FEBS Open Bio, 13 (2), 214-216
DOI 10.1002/2211-5463.13543, PubMed 36562681
[Not Available]
Tidsskr Nor Laegeforen, 143 (13)
DOI 10.4045/tidsskr.23.0496, PubMed 37753760
NKG2A discriminates natural killer cells with a suppressed phenotype in pediatric acute leukemia
J Leukoc Biol (in press)
DOI 10.1093/jleuko/qiad112, PubMed 37738462
High-resolution alignment of single-cell and spatial transcriptomes with CytoSPACE
Nat Biotechnol (in press)
DOI 10.1038/s41587-023-01697-9, PubMed 36879008
Future directions in managing aniridia-associated keratopathy
Surv Ophthalmol, 68 (5), 940-956
DOI 10.1016/j.survophthal.2023.04.003, PubMed 37146692
Germline pathogenic variants in patients with high-grade gastroenteropancreatic neuroendocrine neoplasms
Endocr Relat Cancer, 30 (10)
DOI 10.1530/ERC-23-0057, PubMed 37410378
Germline homozygous missense DEPDC5 variants cause severe refractory early-onset epilepsy, macrocephaly and bilateral polymicrogyria
Hum Mol Genet, 32 (4), 580-594
DOI 10.1093/hmg/ddac225, PubMed 36067010
Clinical performance of volumetric finger-prick sampling for the monitoring of tacrolimus, creatinine and haemoglobin in kidney transplant recipients
Br J Clin Pharmacol (in press)
DOI 10.1111/bcp.15870, PubMed 37537150
Two-locus identity coefficients in pedigrees
G3 (Bethesda), 13 (2)
DOI 10.1093/g3journal/jkac326, PubMed 36525359
Long-Term Use of Amoxicillin Is Associated with Changes in Gene Expression and DNA Methylation in Patients with Low Back Pain and Modic Changes
Antibiotics (Basel), 12 (7)
DOI 10.3390/antibiotics12071217, PubMed 37508313
Cysteine-lowering treatment with mesna against obesity: Proof of concept and results from a human phase I, dose-finding study
Diabetes Obes Metab (in press)
DOI 10.1111/dom.15210, PubMed 37435697
Increased muscle activity during sleep and more RBD symptoms in H1N1-(Pandemrix)-vaccinated narcolepsy type 1 patients compared with their non-narcoleptic siblings
Sleep, 46 (3)
DOI 10.1093/sleep/zsac316, PubMed 36562330
Inhibition of the extracellular enzyme A disintegrin and metalloprotease with thrombospondin motif 4 prevents cardiac fibrosis and dysfunction
Cardiovasc Res, 119 (10), 1915-1927
DOI 10.1093/cvr/cvad078, PubMed 37216909
Transcriptomic pan-cancer analysis using rank-based Bayesian inference
Mol Oncol, 17 (4), 548-563
DOI 10.1002/1878-0261.13354, PubMed 36562628
Quantification of Analgesic and Anti-Inflammatory Lipid Mediators in Long-Term Cryopreserved and Freeze-Dried Preserved Human Amniotic Membrane
Bioengineering (Basel), 10 (6)
DOI 10.3390/bioengineering10060740, PubMed 37370671
The RNA m6A landscape of mouse oocytes and preimplantation embryos
Nat Struct Mol Biol, 30 (5), 703-709
DOI 10.1038/s41594-023-00969-x, PubMed 37081317
Cerebrospinal fluid quinolinic acid is strongly associated with delirium and mortality in hip-fracture patients
J Clin Invest, 133 (2)
DOI 10.1172/JCI163472, PubMed 36409557
SOX2 downregulation of PML increases HCMV gene expression and growth of glioma cells
PLoS Pathog, 19 (4), e1011316
DOI 10.1371/journal.ppat.1011316, PubMed 37058447
Neuraminidase delivered as an APC-targeted DNA vaccine induces protective antibodies against influenza
Mol Ther, 31 (7), 2188-2205
DOI 10.1016/j.ymthe.2023.03.012, PubMed 36926694
Id-neoantigen vaccine induces therapeutic CD8+ T cells against multiple myeloma: H chain-loss escapees cause FLC MM
J Immunother Cancer, 11 (8)
DOI 10.1136/jitc-2023-006944, PubMed 37607769
Whole-exome sequencing in moyamoya patients of Northern-European origin identifies gene variants involved in Nitric Oxide metabolism: A pilot study
Brain Spine, 3, 101745
DOI 10.1016/j.bas.2023.101745, PubMed 37383439
Switching from intravenous to subcutaneous vedolizumab maintenance treatment in patients with inflammatory bowel disease followed by therapeutic drug monitoring
Scand J Gastroenterol, 58 (8), 863-873
DOI 10.1080/00365521.2023.2176252, PubMed 36799155
Characterization of human stem cell-derived hepatic stellate cells and liver sinusoidal endothelial cells during extended in vitro culture
Front Bioeng Biotechnol, 11, 1223737
DOI 10.3389/fbioe.2023.1223737, PubMed 37560536
T cell responses to SARS-CoV-2 vaccination differ by disease-modifying therapy for multiple sclerosis
JCI Insight, 8 (12)
DOI 10.1172/jci.insight.165111, PubMed 37159281
Identifying functional regulatory mutation blocks by integrating genome sequencing and transcriptome data
iScience, 26 (8), 107266
DOI 10.1016/j.isci.2023.107266, PubMed 37520692
Recombinant irisin enhances the extracellular matrix formation, remodeling potential, and differentiation of human periodontal ligament cells cultured in 3D
J Periodontal Res, 58 (2), 336-349
DOI 10.1111/jre.13094, PubMed 36625247
Tear film lipid layer and corneal oxygenation: a new function?
Eye (Lond) (in press)
DOI 10.1038/s41433-023-02557-1, PubMed 37138094
Lowering of Circulating Sclerostin May Increase Risk of Atherosclerosis and Its Risk Factors: Evidence From a Genome-Wide Association Meta-Analysis Followed by Mendelian Randomization
Arthritis Rheumatol, 75 (10), 1781-1792
DOI 10.1002/art.42538, PubMed 37096546
A Roadmap for the Human Gut Cell Atlas
Nat Rev Gastroenterol Hepatol, 20 (9), 597-614
DOI 10.1038/s41575-023-00784-1, PubMed 37258747
Acute normal tissue responses in a murine model following fractionated irradiation of the head and neck with protons or X-rays
Acta Oncol, 1-7 (in press)
DOI 10.1080/0284186X.2023.2254481, PubMed 37703217
Antidepressants escitalopram and venlafaxine up-regulate BDNF promoter IV but down-regulate neurite outgrowth in differentiating SH-SY5Y neurons
Neurochem Int, 169, 105571
DOI 10.1016/j.neuint.2023.105571, PubMed 37451345
Comparative Study of Postmortem Concentrations of Benzodiazepines and Z-Hypnotics in Several Different Matrices
J Anal Toxicol, 47 (3), 287-298
DOI 10.1093/jat/bkac106, PubMed 36542823
Immunogenicity and safety of a two-dose regimen with hepatitis E virus vaccine in healthy adults in rural Bangladesh: A randomized, double-blind, controlled, phase 2/pilot trial
Vaccine, 41 (5), 1059-1066
DOI 10.1016/j.vaccine.2022.12.064, PubMed 36599736
Maternal prenatal cholesterol levels predict offspring weight trajectories during childhood in the Norwegian Mother, Father and Child Cohort Study
BMC Med, 21 (1), 43
DOI 10.1186/s12916-023-02742-9, PubMed 36747215
Plasma-Metanephrines in Patients with Autoimmune Addison's Disease with and without Residual Adrenocortical Function
J Clin Med, 12 (10)
DOI 10.3390/jcm12103602, PubMed 37240708
A new blood based epigenetic age predictor for adolescents and young adults
Sci Rep, 13 (1), 2303
DOI 10.1038/s41598-023-29381-7, PubMed 36759656
Expression of ANK3 moderates the association between childhood trauma and affective traits in severe mental disorders
Sci Rep, 13 (1), 13845
DOI 10.1038/s41598-023-40310-6, PubMed 37620394
Distinct microRNA and protein profiles of extracellular vesicles secreted from myotubes from morbidly obese donors with type 2 diabetes in response to electrical pulse stimulation
Front Physiol, 14, 1143966
DOI 10.3389/fphys.2023.1143966, PubMed 37064893
Humoral Response After 6 or More Successive Doses of SARS-CoV-2 mRNA Vaccines in Kidney Transplant Recipients-Should We Keep Vaccinating?
Transplantation, 107 (10), e279-e280
DOI 10.1097/TP.0000000000004732, PubMed 37496122