Publications (original articles or review articles) published in 2018 from OUS - Department of Immunology (Div LabMed)
84 publications found
Polarity of CD4+ T cells towards the antigen presenting cell is regulated by the Lck adapter TSAd
Sci Rep, 8 (1), 13319
DOI 10.1038/s41598-018-31510-6, PubMed 30190583
Pediatric red cell and platelet transfusions
Transfus Apher Sci, 57 (3), 358-362
DOI 10.1016/j.transci.2018.05.019, PubMed 29804934
Simultaneous Targeting of Multiple Hemagglutinins to APCs for Induction of Broad Immunity against Influenza
J Immunol, 200 (6), 2057-2066
DOI 10.4049/jimmunol.1701088, PubMed 29427414
Staphylococcus aureus Membrane-Derived Vesicles Promote Bacterial Virulence and Confer Protective Immunity in Murine Infection Models
Front Microbiol, 9, 262
DOI 10.3389/fmicb.2018.00262, PubMed 29515544
Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses
Nat Immunol, 19 (7), 776-786
DOI 10.1038/s41590-018-0121-3, PubMed 29784908
A Case of Posttransfusion Purpura with Severe Refractory Thrombocytopenia but No Cutaneous Manifestations
Case Rep Hematol, 2018, 8187659
DOI 10.1155/2018/8187659, PubMed 30510818
Crystal structure of an L chain optimised 14F7 anti-ganglioside Fv suggests a unique tumour-specificity through an unusual H-chain CDR3 architecture
Sci Rep, 8 (1), 10836
DOI 10.1038/s41598-018-28918-5, PubMed 30022069
Inflammation and Mechanical Stress Stimulate Osteogenic Differentiation of Human Aortic Valve Interstitial Cells
Front Physiol, 9, 1635
DOI 10.3389/fphys.2018.01635, PubMed 30524301
TRIM21 mediates antibody inhibition of adenovirus-based gene delivery and vaccination
Proc Natl Acad Sci U S A, 115 (41), 10440-10445
DOI 10.1073/pnas.1806314115, PubMed 30209217
Lamin A, Chromatin and FPLD2: Not Just a Peripheral Ménage-à-Trois
Front Cell Dev Biol, 6, 73
DOI 10.3389/fcell.2018.00073, PubMed 30057899
Laminopathy-causing lamin A mutations reconfigure lamina-associated domains and local spatial chromatin conformation
Nucleus, 9 (1), 216-226
DOI 10.1080/19491034.2018.1449498, PubMed 29517398
The lipodystrophic hotspot lamin A p.R482W mutation deregulates the mesodermal inducer T/Brachyury and early vascular differentiation gene networks
Hum Mol Genet, 27 (8), 1447-1459
DOI 10.1093/hmg/ddy055, PubMed 29438482
Lipophilic components of diesel exhaust particles induce pro-inflammatory responses in human endothelial cells through AhR dependent pathway(s)
Part Fibre Toxicol, 15 (1), 21
DOI 10.1186/s12989-018-0257-1, PubMed 29751765
The Magnitude and IgG Subclass of Antibodies Elicited by Targeted DNA Vaccines Are Influenced by Specificity for APC Surface Molecules
Immunohorizons, 2 (1), 38-53
DOI 10.4049/immunohorizons.1700038, PubMed 31022690
Cytokine profiles and diagnoses in elderly, hospitalized psychiatric patients
BMC Psychiatry, 18 (1), 315
DOI 10.1186/s12888-018-1900-y, PubMed 30261848
From Inflammasome to Exosome-Does Extracellular Vesicle Secretion Constitute an Inflammasome-Dependent Immune Response?
Front Immunol, 9, 2188
DOI 10.3389/fimmu.2018.02188, PubMed 30319640
Discriminative T-cell receptor recognition of highly homologous HLA-DQ2-bound gluten epitopes
J Biol Chem, 294 (3), 941-952
DOI 10.1074/jbc.RA118.005736, PubMed 30455354
Identification of MHC Class Ib Ligands for Stimulatory and Inhibitory Ly49 Receptors and Induction of Potent NK Cell Alloresponses in Rats
J Immunol, 200 (8), 2847-2859
DOI 10.4049/jimmunol.1701464, PubMed 29531166
High-resolution antibody array analysis of proteins from primary human keratinocytes and leukocytes
PLoS One, 13 (12), e0209271
DOI 10.1371/journal.pone.0209271, PubMed 30589857
Microthrombotic renal involvement in an SLE patient with concomitant catastrophic antiphospholipid syndrome: the beneficial effect of rituximab treatment
Lupus, 27 (9), 1552-1558
DOI 10.1177/0961203318768890, PubMed 29635999
Monocytes accumulate in the airways of children with fatal asthma
Clin Exp Allergy, 48 (12), 1631-1639
DOI 10.1111/cea.13265, PubMed 30184280
Tumor Killing by CD4+ T Cells Is Mediated via Induction of Inducible Nitric Oxide Synthase-Dependent Macrophage Cytotoxicity
Front Immunol, 9, 1684
DOI 10.3389/fimmu.2018.01684, PubMed 30083157
Normal development of mice lacking PAXX, the paralogue of XRCC4 and XLF
FEBS Open Bio, 8 (3), 426-434
DOI 10.1002/2211-5463.12381, PubMed 29511619
Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population
Front Immunol, 9, 2664
DOI 10.3389/fimmu.2018.02664, PubMed 30515158
Wilhelm His' lasting insights into hindbrain and cranial ganglia development and evolution
Dev Biol, 444 Suppl 1 (Suppl 1), S14-S24
DOI 10.1016/j.ydbio.2018.02.001, PubMed 29447907
A human endothelial cell-based recycling assay for screening of FcRn targeted molecules
Nat Commun, 9 (1), 621
DOI 10.1038/s41467-018-03061-x, PubMed 29434196
Corneal Involvement of Patients with Polymyositis and Dermatomyositis
Ocul Immunol Inflamm, 28 (1), 58-66
DOI 10.1080/09273948.2018.1547407, PubMed 30444429
Lack of Association among Peptidyl Arginine Deiminase Type 4 Autoantibodies, PADI4 Polymorphisms, and Clinical Characteristics in Rheumatoid Arthritis
J Rheumatol, 45 (9), 1211-1219
DOI 10.3899/jrheum.170769, PubMed 29858238
Soluble T-cell receptor design influences functional yield in an E. coli chaperone-assisted expression system
PLoS One, 13 (4), e0195868
DOI 10.1371/journal.pone.0195868, PubMed 29649333
Exploration of 27 plasma immune markers: a cross-sectional comparison of 64 old psychiatric inpatients having unipolar major depression and 18 non-depressed old persons
BMC Geriatr, 18 (1), 149
DOI 10.1186/s12877-018-0836-x, PubMed 29940870
The Palliative Radiotherapy and Inflammation Study (PRAIS) - protocol for a longitudinal observational multicenter study on patients with cancer induced bone pain
BMC Palliat Care, 17 (1), 110
DOI 10.1186/s12904-018-0362-9, PubMed 30266081
Granulocyte and monocyte CD11b expression during plasma separation is dependent on complement factor 5 (C5) - an ex vivo study with blood from a C5-deficient individual
APMIS, 126 (4), 342-352
DOI 10.1111/apm.12821, PubMed 29575196
Cryopreservation of primary B cells minimally influences their signaling responses
Sci Rep, 8 (1), 17651
DOI 10.1038/s41598-018-36121-9, PubMed 30518828
Associations between complement pathways activity, mannose-binding lectin, and odds of unprovoked venous thromboembolism
Thromb Res, 169, 50-56
DOI 10.1016/j.thromres.2018.06.019, PubMed 30015228
Plasma Cells Are the Most Abundant Gluten Peptide MHC-expressing Cells in Inflamed Intestinal Tissues From Patients With Celiac Disease
Gastroenterology, 156 (5), 1428-1439.e10
DOI 10.1053/j.gastro.2018.12.013, PubMed 30593798
mRNA vaccination with charge-altering releasable transporters elicits human T cell responses and cures established tumors in mice
Proc Natl Acad Sci U S A, 115 (39), E9153-E9161
DOI 10.1073/pnas.1810002115, PubMed 30201728
CD4+ T-cell-Mediated Rejection of MHC Class II-Positive Tumor Cells Is Dependent on Antigen Secretion and Indirect Presentation on Host APCs
Cancer Res, 78 (16), 4573-4585
DOI 10.1158/0008-5472.CAN-17-2426, PubMed 29752262
One-step generation of monoclonal B cell receptor mice capable of isotype switching and somatic hypermutation
J Exp Med, 215 (10), 2686-2695
DOI 10.1084/jem.20172064, PubMed 30181412
Expression of inflammatory cytokines in mesenchymal stromal cells is sensitive to culture conditions and simple cell manipulations
Exp Cell Res, 374 (1), 122-127
DOI 10.1016/j.yexcr.2018.11.014, PubMed 30496759
Uhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a
Nat Commun, 9 (1), 2583
DOI 10.1038/s41467-018-04818-0, PubMed 29968706
Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction
Int J Cardiol, 271, 1-7
DOI 10.1016/j.ijcard.2018.04.136, PubMed 29961572
Locomotor central pattern generator excitability states and serotonin sensitivity after spontaneous recovery from a neonatal lumbar spinal cord injury
Brain Res, 1708, 10-19
DOI 10.1016/j.brainres.2018.12.001, PubMed 30521786
Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Controls Fibroblast Growth Factor Receptor (FGFR) 1 Activity and Influences Sensitivity to FGFR Kinase Inhibitors
Mol Cell Proteomics, 17 (5), 850-870
DOI 10.1074/mcp.RA117.000538, PubMed 29371290
HLA -A, -C, -B, -DRB1, -DQB1 and -DPB1 allele and haplotype frequencies in 4514 healthy Norwegians
Hum Immunol, 79 (7), 527-529
DOI 10.1016/j.humimm.2018.04.012, PubMed 29684411
Complement component 5 does not interfere with physiological hemostasis but is essential for Escherichia coli-induced coagulation accompanied by Toll-like receptor 4
Clin Exp Immunol, 196 (1), 97-110
DOI 10.1111/cei.13240, PubMed 30444525
Advances in stem cell therapy for amyotrophic lateral sclerosis
Expert Opin Biol Ther, 18 (8), 865-881
DOI 10.1080/14712598.2018.1503248, PubMed 30025485
Minimal residual disease quantification by flow cytometry provides reliable risk stratification in T-cell acute lymphoblastic leukemia
Leukemia, 33 (6), 1324-1336
DOI 10.1038/s41375-018-0307-6, PubMed 30552401
Patterns of Invasive Growth in Malignant Gliomas-The Hippocampus Emerges as an Invasion-Spared Brain Region
Neoplasia, 20 (7), 643-656
DOI 10.1016/j.neo.2018.04.001, PubMed 29793116
Single cell profiling of phospho-protein levels in chronic lymphocytic leukemia
Oncotarget, 9 (10), 9273-9284
DOI 10.18632/oncotarget.23949, PubMed 29507689
Corneal Manifestations of Systemic Sclerosis
Ocul Immunol Inflamm, 27 (6), 968-977
DOI 10.1080/09273948.2018.1489556, PubMed 30015530
Splicing of platelet resident pre-mRNAs upon activation by physiological stimuli results in functionally relevant proteome modifications
Sci Rep, 8 (1), 498
DOI 10.1038/s41598-017-18985-5, PubMed 29323256
Human and mouse albumin bind their respective neonatal Fc receptors differently
Sci Rep, 8 (1), 14648
DOI 10.1038/s41598-018-32817-0, PubMed 30279529
Animal models for evaluation of albumin-based therapeutics
Curr. Opin. Chem. Eng., 19, 68-76
DOI 10.1016/j.coche.2017.11.007
Donor health assessment - When is blood donation safe?
Transfus Apher Sci, 58 (1), 113-116
DOI 10.1016/j.transci.2018.12.016, PubMed 30630765
The tankyrase inhibitor G007-LK inhibits small intestine LGR5+ stem cell proliferation without altering tissue morphology
Biol Res, 51 (1), 3
DOI 10.1186/s40659-017-0151-6, PubMed 29316982
Acute heart failure following myocardial infarction: complement activation correlates with the severity of heart failure in patients developing cardiogenic shock
ESC Heart Fail, 5 (3), 292-301
DOI 10.1002/ehf2.12266, PubMed 29424484
IL-6 Receptor Inhibition by Tocilizumab Attenuated Expression of C5a Receptor 1 and 2 in Non-ST-Elevation Myocardial Infarction
Front Immunol, 9, 2035
DOI 10.3389/fimmu.2018.02035, PubMed 30258440
Soluble IL-1 receptor 2 is associated with left ventricular remodelling in patients with ST-elevation myocardial infarction
Int J Cardiol, 268, 187-192
DOI 10.1016/j.ijcard.2018.05.032, PubMed 29853279
Current use of biosimilar G-CSF for haematopoietic stem cell mobilisation
Bone Marrow Transplant, 54 (6), 858-866
DOI 10.1038/s41409-018-0350-y, PubMed 30283148
Predictors of chronic fatigue in adolescents six months after acute Epstein-Barr virus infection: A prospective cohort study
Brain Behav Immun, 75, 94-100
DOI 10.1016/j.bbi.2018.09.023, PubMed 30261303
Directed reprogramming of comprehensively characterized dental pulp stem cells extracted from natal tooth
Sci Rep, 8 (1), 6168
DOI 10.1038/s41598-018-24421-z, PubMed 29670257
High neopterin and IP-10 levels in cerebrospinal fluid are associated with neurotoxic tryptophan metabolites in acute central nervous system infections
J Neuroinflammation, 15 (1), 327
DOI 10.1186/s12974-018-1366-3, PubMed 30470234
Recellularization of Decellularized Venous Grafts Using Peripheral Blood: A Critical Evaluation
EBioMedicine, 32, 215-222
DOI 10.1016/j.ebiom.2018.05.012, PubMed 29779699
Disease-driving CD4+ T cell clonotypes persist for decades in celiac disease
J Clin Invest, 128 (6), 2642-2650
DOI 10.1172/JCI98819, PubMed 29757191
The SysteMHC Atlas project
Nucleic Acids Res, 46 (D1), D1237-D1247
DOI 10.1093/nar/gkx664, PubMed 28985418
A high-throughput pipeline for validation of antibodies
Nat Methods, 15 (11), 909-912
DOI 10.1038/s41592-018-0179-8, PubMed 30377371
Low Levels of Immunoglobulins and Mannose-Binding Lectin Are Not Associated With Etiology, Severity, or Outcome in Community-Acquired Pneumonia
Open Forum Infect Dis, 5 (2), ofy002
DOI 10.1093/ofid/ofy002, PubMed 29410975
Pharmaceutical compounding of aflibercept in prefilled syringes does not affect structural integrity, stability or VEGF and Fc binding properties
Sci Rep, 8 (1), 2101
DOI 10.1038/s41598-018-20525-8, PubMed 29391560
Staphylococcus aureus-induced complement activation promotes tissue factor-mediated coagulation
J Thromb Haemost, 16 (5), 905-918
DOI 10.1111/jth.13979, PubMed 29437288
Dystonia-deafness syndrome caused by ACTB p.Arg183Trp heterozygosity shows striatal dopaminergic dysfunction and response to pallidal stimulation
J Neurodev Disord, 10 (1), 17
DOI 10.1186/s11689-018-9235-z, PubMed 29788902
Ultracentrifugation versus kit exosome isolation: nanoLC-MS and other tools reveal similar performance biomarkers, but also contaminations
Future Sci OA, 5 (1), FSO359
DOI 10.4155/fsoa-2018-0088, PubMed 30652024
C-C Motif Ligand 20 (CCL20) and C-C Motif Chemokine Receptor 6 (CCR6) in Human Peripheral Blood Mononuclear Cells: Dysregulated in Ulcerative Colitis and a Potential Role for CCL20 in IL-1β Release
Int J Mol Sci, 19 (10)
DOI 10.3390/ijms19103257, PubMed 30347808
Human IgG lacking effector functions demonstrate lower FcRn-binding and reduced transplacental transport
Mol Immunol, 95, 1-9
DOI 10.1016/j.molimm.2018.01.006, PubMed 29367080
Prenatal iron exposure and childhood type 1 diabetes
Sci Rep, 8 (1), 9067
DOI 10.1038/s41598-018-27391-4, PubMed 29899542
Effect of Genetic and Laboratory Findings on Clinical Course of Antisynthetase Syndrome in a Hungarian Cohort
Biomed Res Int, 2018, 6416378
DOI 10.1155/2018/6416378, PubMed 30498759
Determination of fetal RHD type in plasma of RhD negative pregnant women
Scand J Clin Lab Invest, 78 (5), 411-416
DOI 10.1080/00365513.2018.1475681, PubMed 29869532
Combined Inhibition of C5 and CD14 Attenuates Systemic Inflammation in a Piglet Model of Meconium Aspiration Syndrome
Neonatology, 113 (4), 322-330
DOI 10.1159/000486542, PubMed 29486477
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for pseudomyxoma peritonei in a liver-transplanted patient: a case report
World J Surg Oncol, 16 (1), 180
DOI 10.1186/s12957-018-1482-7, PubMed 30185175
G1m1 predominance of intrathecal virus-specific antibodies in multiple sclerosis
Ann Clin Transl Neurol, 5 (10), 1303-1309
DOI 10.1002/acn3.642, PubMed 30349866
Characterization of the Small Intestinal Lesion in Celiac Disease by Label-Free Quantitative Mass Spectrometry
Am J Pathol, 188 (7), 1563-1579
DOI 10.1016/j.ajpath.2018.03.017, PubMed 29684362
Ribosomal DNA copy loss and repeat instability in ATRX-mutated cancers
Proc Natl Acad Sci U S A, 115 (18), 4737-4742
DOI 10.1073/pnas.1720391115, PubMed 29669917
Addressing Ethical and Procedural Principles for Unrelated Allogeneic Hematopoietic Progenitor Cell Donation in a Changing Medical Environment
Biol Blood Marrow Transplant, 24 (5), 887-894
DOI 10.1016/j.bbmt.2018.01.018, PubMed 29410372
Cytokine profiling and post-transfusion haemoglobin increment in patients with haematological diseases
Vox Sang, 113 (7), 657-668
DOI 10.1111/vox.12703, PubMed 30159896
Iron oxide nanoparticles enhance Toll-like receptor-induced cytokines in a particle size- and actin-dependent manner in human blood
Nanomedicine (Lond), 13 (14), 1773-1785
DOI 10.2217/nnm-2017-0362, PubMed 30084726