Publications (original articles or review articles) published in 2019 from OUS - Department of Immunology (Div LabMed)
102 publications found
Multi-pathway Protective Effects of MicroRNAs on Human Chondrocytes in an In Vitro Model of Osteoarthritis
Mol Ther Nucleic Acids, 17, 776-790
DOI 10.1016/j.omtn.2019.07.011, PubMed 31446120
Interaction Proteomics Identifies ERbeta Association with Chromatin Repressive Complexes to Inhibit Cholesterol Biosynthesis and Exert An Oncosuppressive Role in Triple-negative Breast Cancer
Mol Cell Proteomics, 19 (2), 245-260
DOI 10.1074/mcp.RA119.001817, PubMed 31792072
Enhanced germinal center reaction by targeting vaccine antigen to major histocompatibility complex class II molecules
NPJ Vaccines, 4, 9
DOI 10.1038/s41541-019-0101-0, PubMed 30775000
Evaluation of Objective Signs and Subjective Symptoms of Dry Eye Disease in Patients with Inflammatory Bowel Disease
Biomed Res Int, 2019, 8310583
DOI 10.1155/2019/8310583, PubMed 30729131
Resident memory CD8 T cells persist for years in human small intestine
J Exp Med, 216 (10), 2412-2426
DOI 10.1084/jem.20190414, PubMed 31337737
Diagnosis and outcome of acute respiratory failure in immunocompromised patients after bronchoscopy
Eur Respir J, 54 (1)
DOI 10.1183/13993003.02442-2018, PubMed 31109985
Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses
Sci Adv, 5 (12), eaax9586
DOI 10.1126/sciadv.aax9586, PubMed 31897428
Interstitial cells in calcified aortic valves have reduced differentiation potential and stem cell-like properties
Sci Rep, 9 (1), 12934
DOI 10.1038/s41598-019-49016-0, PubMed 31506459
CD4+ T cells indirectly kill tumor cells via induction of cytotoxic macrophages in mouse models
Cancer Immunol Immunother, 68 (11), 1865-1873
DOI 10.1007/s00262-019-02374-0, PubMed 31448380
Complement C4 Prevents Viral Infection through Capsid Inactivation
Cell Host Microbe, 25 (4), 617-629.e7
DOI 10.1016/j.chom.2019.02.016, PubMed 30926239
Key role of the number of complement receptor 1 on erythrocytes for binding of Escherichia coli to erythrocytes and for leukocyte phagocytosis and oxidative burst in human whole blood
Mol Immunol, 114, 139-148
DOI 10.1016/j.molimm.2019.07.014, PubMed 31352230
EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology
SLAS Discov, 24 (3), 398-413
DOI 10.1177/2472555218816276, PubMed 30616481
Nuclear Lamin B1 Interactions With Chromatin During the Circadian Cycle Are Uncoupled From Periodic Gene Expression
Front Genet, 10, 917
DOI 10.3389/fgene.2019.00917, PubMed 31632442
[Premature infants should receive early vaccination against rotavirus]
Tidsskr Nor Laegeforen, 139 (10)
DOI 10.4045/tidsskr.19.0079, PubMed 31238656
Changes in cytokines during treatment of elderly, hospitalized psychiatric patients - a naturalistic study
Psychoneuroendocrinology, 108, 135-139
DOI 10.1016/j.psyneuen.2019.06.014, PubMed 31276906
Deciphering myeloid-derived suppressor cells: isolation and markers in humans, mice and non-human primates
Cancer Immunol Immunother, 68 (4), 687-697
DOI 10.1007/s00262-019-02302-2, PubMed 30684003
The PI3K p110δ Isoform Inhibitor Idelalisib Preferentially Inhibits Human Regulatory T Cell Function
J Immunol, 202 (5), 1397-1405
DOI 10.4049/jimmunol.1701703, PubMed 30692213
Distinct phenotype of CD4+ T cells driving celiac disease identified in multiple autoimmune conditions
Nat Med, 25 (5), 734-737
DOI 10.1038/s41591-019-0403-9, PubMed 30911136
Therapeutic and Diagnostic Implications of T Cell Scarring in Celiac Disease and Beyond
Trends Mol Med, 25 (10), 836-852
DOI 10.1016/j.molmed.2019.05.009, PubMed 31331739
Noninvasive fetal RHD genotyping to guide targeted anti-D prophylaxis-an external quality assessment workshop
Vox Sang, 114 (4), 386-393
DOI 10.1111/vox.12768, PubMed 30834546
Finding Friends in the Crowd: Three-Dimensional Cliques of Topological Genomic Domains
Front Genet, 10, 602
DOI 10.3389/fgene.2019.00602, PubMed 31275364
Corneal Manifestations of Inflammatory Bowel Disease
Semin Ophthalmol, 34 (7-8), 543-550
DOI 10.1080/08820538.2019.1684525, PubMed 31657260
On the immune response to barley in celiac disease: Biased and public T-cell receptor usage to a barley unique and immunodominant gluten epitope
Eur J Immunol, 50 (2), 256-269
DOI 10.1002/eji.201948253, PubMed 31628754
Elevated Complement C3 and C4 Levels are Associated with Postnatal Pregnancy-Related Venous Thrombosis
Thromb Haemost, 119 (9), 1481-1488
DOI 10.1055/s-0039-1692426, PubMed 31254974
Single-cell TCR sequencing of gut intraepithelial γδ T cells reveals a vast and diverse repertoire in celiac disease
Mucosal Immunol, 13 (2), 313-321
DOI 10.1038/s41385-019-0222-9, PubMed 31728027
Deep sequencing of a recurrent oligodendroglioma and the derived xenografts reveals new insights into the evolution of human oligodendroglioma and candidate driver genes
Oncotarget, 10 (38), 3641-3653
DOI 10.18632/oncotarget.26950, PubMed 31217899
Interplay of lamin A and lamin B LADs on the radial positioning of chromatin
Nucleus, 10 (1), 7-20
DOI 10.1080/19491034.2019.1570810, PubMed 30663495
TRIM21-From Intracellular Immunity to Therapy
Front Immunol, 10, 2049
DOI 10.3389/fimmu.2019.02049, PubMed 31555278
Mosaic deletion patterns of the human antibody heavy chain gene locus shown by Bayesian haplotyping
Nat Commun, 10 (1), 628
DOI 10.1038/s41467-019-08489-3, PubMed 30733445
Cytokine release and gastrointestinal symptoms after gluten challenge in celiac disease
Sci Adv, 5 (8), eaaw7756
DOI 10.1126/sciadv.aaw7756, PubMed 31457091
The synthetic antimicrobial peptide LTX21 induces inflammatory responses in a human whole blood model and a murine peritoneum model
APMIS, 127 (6), 475-483
DOI 10.1111/apm.12946, PubMed 30916807
Cholesterol Crystals Induce Coagulation Activation through Complement-Dependent Expression of Monocytic Tissue Factor
J Immunol, 203 (4), 853-863
DOI 10.4049/jimmunol.1900503, PubMed 31270150
Targeting of HA to chemokine receptors induces strong and cross-reactive T cell responses after DNA vaccination in pigs
Vaccine, 38 (6), 1280-1285
DOI 10.1016/j.vaccine.2019.11.084, PubMed 31836256
Endocytosis Deficient Murine Xcl1-Fusion Vaccine Enhances Protective Antibody Responses in Mice
Front Immunol, 10, 1086
DOI 10.3389/fimmu.2019.01086, PubMed 31156636
Perioperative Infusion of Glucagon-Like Peptide-1 Prevents Insulin Resistance After Surgical Trauma in Female Pigs
Endocrinology, 160 (12), 2892-2902
DOI 10.1210/en.2019-00374, PubMed 31589305
Comparison of cytokine changes in three different lipoprotein apheresis systems in an ex vivo whole blood model
J Clin Apher, 35 (2), 104-116
DOI 10.1002/jca.21765, PubMed 31782556
Structural and Functional Dynamics of Staphylococcus aureus Biofilms and Biofilm Matrix Proteins on Different Clinical Materials
Microorganisms, 7 (12)
DOI 10.3390/microorganisms7120584, PubMed 31756969
Tumor necrosis factor inhibitors are associated with reduced complement activation in spondylarthropathies: An observational study
PLoS One, 14 (7), e0220079
DOI 10.1371/journal.pone.0220079, PubMed 31335881
Selective and marked decrease of complement receptor C5aR2 in human thoracic aortic aneurysms: a dysregulation with potential inflammatory effects
Open Heart, 6 (2), e001098
DOI 10.1136/openhrt-2019-001098, PubMed 31798913
Epitope Selection for HLA-DQ2 Presentation: Implications for Celiac Disease and Viral Defense
J Immunol, 202 (9), 2558-2569
DOI 10.4049/jimmunol.1801454, PubMed 30926644
B cell receptor ligation induces display of V-region peptides on MHC class II molecules to T cells
Proc Natl Acad Sci U S A, 116 (51), 25850-25859
DOI 10.1073/pnas.1902836116, PubMed 31796587
Complement activation assessed by the plasma terminal complement complex and future risk of venous thromboembolism
J Thromb Haemost, 17 (6), 934-943
DOI 10.1111/jth.14438, PubMed 30920726
Targeting the MHC Ligandome by Use of TCR-Like Antibodies
Antibodies (Basel), 8 (2)
DOI 10.3390/antib8020032, PubMed 31544838
Local Delivery of Ox40l, Cd80, and Cd86 mRNA Kindles Global Anticancer Immunity
Cancer Res, 79 (7), 1624-1634
DOI 10.1158/0008-5472.CAN-18-2867, PubMed 30692215
3D bioprinting of hydrogel constructs with cell and material gradients for the regeneration of full-thickness chondral defect using a microfluidic printing head
Biofabrication, 11 (4), 044101
DOI 10.1088/1758-5090/ab2622, PubMed 31151123
Effects of gamma radiation sterilization on the structural and biological properties of decellularized corneal xenografts
Acta Biomater, 96, 330-344
DOI 10.1016/j.actbio.2019.07.002, PubMed 31284096
Efficient T cell-B cell collaboration guides autoantibody epitope bias and onset of celiac disease
Proc Natl Acad Sci U S A, 116 (30), 15134-15139
DOI 10.1073/pnas.1901561116, PubMed 31285344
IgE-sensitization to food and inhalant allergens in IBD patients compared with normal blood donors at Oslo University Hospital, Norway
Scand J Gastroenterol, 54 (9), 1107-1110
DOI 10.1080/00365521.2019.1663445, PubMed 31524013
Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
Sci Rep, 9 (1), 167 (Retracted)
DOI 10.1038/s41598-018-35367-7, PubMed 30655568
Single-Cell RNA Sequencing of In Vitro Expanded Chondrocytes: MSC-Like Cells With No Evidence of Distinct Subsets
Cartilage, 13 (2_suppl), 774S-784S
DOI 10.1177/1947603519847746, PubMed 31072202
Robust profiling of microRNAs and isomiRs in human plasma exosomes across 46 individuals
Sci Rep, 9 (1), 19999
DOI 10.1038/s41598-019-56593-7, PubMed 31882820
Ocular manifestations of rheumatic diseases
Int Ophthalmol, 40 (2), 503-510
DOI 10.1007/s10792-019-01183-9, PubMed 31583550
HLA-DRB3*01:01 exhibits a dose-dependent impact on HPA-1a antibody levels in HPA-1a-immunized women
Blood Adv, 3 (7), 945-951
DOI 10.1182/bloodadvances.2019032227, PubMed 30923048
3D bioprinted hydrogel model incorporating β-tricalcium phosphate for calcified cartilage tissue engineering
Biofabrication, 11 (3), 035016
DOI 10.1088/1758-5090/ab15cb, PubMed 30943457
Pseudo-anaphylaxis to Polyethylene Glycol (PEG)-Coated Liposomes: Roles of Anti-PEG IgM and Complement Activation in a Porcine Model of Human Infusion Reactions
ACS Nano, 13 (8), 9315-9324
DOI 10.1021/acsnano.9b03942, PubMed 31348638
Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection
EMBO J, 38 (21), e101365
DOI 10.15252/embj.2018101365, PubMed 31468569
Plasma levels of mannose-binding lectin and future risk of venous thromboembolism
J Thromb Haemost, 17 (10), 1661-1669
DOI 10.1111/jth.14539, PubMed 31220397
3D cell culture models and organ-on-a-chip: Meet separation science and mass spectrometry
Electrophoresis, 41 (1-2), 56-64
DOI 10.1002/elps.201900170, PubMed 31544246
A new method for pharmaceutical compounding and storage of anti-VEGF biologics for intravitreal use in silicone oil-free prefilled plastic syringes
Sci Rep, 9 (1), 18021
DOI 10.1038/s41598-019-54226-7, PubMed 31792234
Molecular Profiling Defines Evolutionarily Conserved Transcription Factor Signatures of Major Vestibulospinal Neuron Groups
eNeuro, 6 (1)
DOI 10.1523/ENEURO.0475-18.2019, PubMed 30899776
Legumain is upregulated in acute cardiovascular events and associated with improved outcome - potentially related to anti-inflammatory effects on macrophages
Atherosclerosis, 296, 74-82
DOI 10.1016/j.atherosclerosis.2019.12.008, PubMed 31870625
Dendritic cell targeted Ccl3- and Xcl1-fusion DNA vaccines differ in induced immune responses and optimal delivery site
Sci Rep, 9 (1), 1820
DOI 10.1038/s41598-018-38080-7, PubMed 30755656
Impaired HDL Function Amplifies Systemic Inflammation in Common Variable Immunodeficiency
Sci Rep, 9 (1), 9427
DOI 10.1038/s41598-019-45861-1, PubMed 31263122
Functional design of pH-responsive folate-targeted polymer-coated gold nanoparticles for drug delivery and in vivo therapy in breast cancer
Int J Nanomedicine, 14, 8285-8302
DOI 10.2147/IJN.S215142, PubMed 31802866
Agaricus blazei-Based Mushroom Extract Supplementation to Birch Allergic Blood Donors: A Randomized Clinical Trial
Nutrients, 11 (10)
DOI 10.3390/nu11102339, PubMed 31581605
'Stealth' corporate innovation: an emerging threat for therapeutic drug development
Nat Immunol, 20 (11), 1409-1413
DOI 10.1038/s41590-019-0503-1, PubMed 31562490
The cardiac syndecan-4 interactome reveals a role for syndecan-4 in nuclear translocation of muscle LIM protein (MLP)
J Biol Chem, 294 (22), 8717-8731
DOI 10.1074/jbc.RA118.006423, PubMed 30967474
Single-Cell Transcriptomics of Regulatory T Cells Reveals Trajectories of Tissue Adaptation
Immunity, 50 (2), 493-504.e7
DOI 10.1016/j.immuni.2019.01.001, PubMed 30737144
Needle-free delivery of DNA: Targeting of hemagglutinin to MHC class II molecules protects rhesus macaques against H1N1 influenza
Vaccine, 37 (6), 817-826
DOI 10.1016/j.vaccine.2018.12.049, PubMed 30638800
B cell depletion in the treatment of multiple sclerosis
Expert Opin Biol Ther, 19 (3), 261-271
DOI 10.1080/14712598.2019.1568407, PubMed 30632834
Targeting B-cell malignancies with the beta-emitting anti-CD37 radioimmunoconjugate 177Lu-NNV003
Eur J Nucl Med Mol Imaging, 46 (11), 2311-2321
DOI 10.1007/s00259-019-04417-1, PubMed 31309259
The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei
Sci Data, 6 (1), 173
DOI 10.1038/s41597-019-0179-2, PubMed 31527615
Inhibition of histone methyltransferase DOT1L silences ERα gene and blocks proliferation of antiestrogen-resistant breast cancer cells
Sci Adv, 5 (2), eaav5590
DOI 10.1126/sciadv.aav5590, PubMed 30775443
Biphasic Release of the Alarmin High Mobility Group Box 1 Protein Early After Trauma Predicts Poor Clinical Outcome
Crit Care Med, 47 (8), e614-e622
DOI 10.1097/CCM.0000000000003800, PubMed 31162203
Long-range interactions between topologically associating domains shape the four-dimensional genome during differentiation
Nat Genet, 51 (5), 835-843
DOI 10.1038/s41588-019-0392-0, PubMed 31011212
Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model
PLoS One, 14 (6), e0218624
DOI 10.1371/journal.pone.0218624, PubMed 31247004
Differential Levels and Phosphorylation of Type 1 Inositol 1,4,5-Trisphosphate Receptor in Four Different Murine Models of Huntington Disease
J Huntingtons Dis, 8 (3), 271-289
DOI 10.3233/JHD-180301, PubMed 31256144
The Neonatal Fc Receptor (FcRn): A Misnomer?
Front Immunol, 10, 1540
DOI 10.3389/fimmu.2019.01540, PubMed 31354709
Two novel HLA-DQ2.5-restricted gluten T cell epitopes in the DQ2.5-glia-γ4 epitope family
Immunogenetics, 71 (10), 665-667
DOI 10.1007/s00251-019-01138-5, PubMed 31673720
Mitochondrial stress response triggered by defects in protein synthesis quality control
Life Sci Alliance, 2 (1)
DOI 10.26508/lsa.201800219, PubMed 30683687
Growth Mode and Carbon Source Impact the Surfaceome Dynamics of Lactobacillus rhamnosus GG
Front Microbiol, 10, 1272
DOI 10.3389/fmicb.2019.01272, PubMed 31231350
Increased Complement Factor B and Bb Levels Are Associated with Mortality in Patients with Severe Aortic Stenosis
J Immunol, 203 (7), 1973-1980
DOI 10.4049/jimmunol.1801244, PubMed 31492744
Binding to nanopatterned antigens is dominated by the spatial tolerance of antibodies
Nat Nanotechnol, 14 (2), 184-190
DOI 10.1038/s41565-018-0336-3, PubMed 30643273
Phagocytosis of live and dead Escherichia coli and Staphylococcus aureus in human whole blood is markedly reduced by combined inhibition of C5aR1 and CD14
Mol Immunol, 112, 131-139
DOI 10.1016/j.molimm.2019.03.014, PubMed 31102985
An in vitro assay for biomarker discovery and dose prediction applied to ibrutinib plus venetoclax treatment of CLL
Leukemia, 34 (2), 478-487
DOI 10.1038/s41375-019-0569-7, PubMed 31471562
Transcriptional profiling of human intestinal plasma cells reveals effector functions beyond antibody production
United European Gastroenterol J, 7 (10), 1399-1407
DOI 10.1177/2050640619862461, PubMed 31839965
NLRP3 Inflammasome: A Novel Player in Metabolically Induced Inflammation-Potential Influence on the Myocardium
J Cardiovasc Pharmacol, 74 (4), 276-284
DOI 10.1097/FJC.0000000000000704, PubMed 31584530
MEK Inhibition Induces Canonical WNT Signaling through YAP in KRAS Mutated HCT-15 Cells, and a Cancer Preventive FOXO3/FOXM1 Ratio in Combination with TNKS Inhibition
Cancers (Basel), 11 (2)
DOI 10.3390/cancers11020164, PubMed 30717152
Update 2020: nomenclature and listing of celiac disease-relevant gluten epitopes recognized by CD4+ T cells
Immunogenetics, 72 (1-2), 85-88
DOI 10.1007/s00251-019-01141-w, PubMed 31735991
PML modulates H3.3 targeting to telomeric and centromeric repeats in mouse fibroblasts
Biochem Biophys Res Commun, 511 (4), 882-888
DOI 10.1016/j.bbrc.2019.02.087, PubMed 30850162
Impact of humanised isolation and culture conditions on stemness and osteogenic potential of bone marrow derived mesenchymal stromal cells
Sci Rep, 9 (1), 16031
DOI 10.1038/s41598-019-52442-9, PubMed 31690774
A Wide Spectrum of Ocular Manifestations Signify Patients with Systemic Sclerosis
Ocul Immunol Inflamm, 29 (1), 81-89
DOI 10.1080/09273948.2019.1657467, PubMed 31577461
Maternal microchimerism in cord blood and risk of childhood-onset type 1 diabetes
Pediatr Diabetes, 20 (6), 728-735
DOI 10.1111/pedi.12875, PubMed 31173445
Maternal and Newborn Vitamin D-Binding Protein, Vitamin D Levels, Vitamin D Receptor Genotype, and Childhood Type 1 Diabetes
Diabetes Care, 42 (4), 553-559
DOI 10.2337/dc18-2176, PubMed 30692241
Targeting Conventional Dendritic Cells to Fine-Tune Antibody Responses
Front Immunol, 10, 1529
DOI 10.3389/fimmu.2019.01529, PubMed 31333661
Complement Component C5 and TLR Molecule CD14 Mediate Heme-Induced Thromboinflammation in Human Blood
J Immunol, 203 (6), 1571-1578
DOI 10.4049/jimmunol.1900047, PubMed 31413105
The Role of Complement in Liver Injury, Regeneration, and Transplantation
Hepatology, 70 (2), 725-736
DOI 10.1002/hep.30508, PubMed 30653682
Fetal and neonatal alloimmune thrombocytopenia - The Norwegian management model
Transfus Apher Sci, 59 (1), 102711
DOI 10.1016/j.transci.2019.102711, PubMed 31911047
Persistence of intrathecal oligoclonal B cells and IgG in multiple sclerosis
J Neuroimmunol, 333, 576966
DOI 10.1016/j.jneuroim.2019.576966, PubMed 31153015
Cytokine release after gluten ingestion differentiates coeliac disease from self-reported gluten sensitivity
United European Gastroenterol J, 8 (1), 108-118
DOI 10.1177/2050640619874173, PubMed 32213060
Low Cellular NAD+ Compromises Lipopolysaccharide-Induced Inflammatory Responses via Inhibiting TLR4 Signal Transduction in Human Monocytes
J Immunol, 203 (6), 1598-1608
DOI 10.4049/jimmunol.1801382, PubMed 31427442
Evaluating plasma extracellular vesicle microRNAs as possible biomarkers for osteoarthritis
Osteoarthr Cartil Open, 1 (3-4), 100018
DOI 10.1016/j.ocarto.2019.100018, PubMed 36475003