Publications (original articles or review articles) published in 2020 from OUS - Department of Immunology (Div LabMed)
74 publications found
Pancreas-on-a-Chip Technology for Transplantation Applications
Curr Diab Rep, 20 (12), 72
DOI 10.1007/s11892-020-01357-1, PubMed 33206261
Engineered albumin-functionalized nanoparticles for improved FcRn binding enhance oral delivery of insulin
J Control Release, 327, 161-173
DOI 10.1016/j.jconrel.2020.08.005, PubMed 32771477
A method for differentiating human induced pluripotent stem cells toward functional cardiomyocytes in 96-well microplates
Sci Rep, 10 (1), 18498
DOI 10.1038/s41598-020-73656-2, PubMed 33116175
Intestinal inflammatory profile shows increase in a diversity of biomarkers in irritable bowel syndrome
Scand J Gastroenterol, 55 (5), 537-542
DOI 10.1080/00365521.2020.1754455, PubMed 32329383
An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics
Sci Transl Med, 12 (565)
DOI 10.1126/scitranslmed.abb0580, PubMed 33055243
Five decades with grandparent donors: The Norwegian strategy and experience
Pediatr Transplant, 24 (6), e13751
DOI 10.1111/petr.13751, PubMed 32485019
Lamina-associated domains: peripheral matters and internal affairs
Genome Biol, 21 (1), 85
DOI 10.1186/s13059-020-02003-5, PubMed 32241294
Extensive Changes in Transcriptomic "Fingerprints" and Immunological Cells in the Large Organs of Patients Dying of Acute Septic Shock and Multiple Organ Failure Caused by Neisseria meningitidis
Front Cell Infect Microbiol, 10, 42
DOI 10.3389/fcimb.2020.00042, PubMed 32154187
A DNA Vaccine That Encodes an Antigen-Presenting Cell-Specific Heterodimeric Protein Protects against Cancer and Influenza
Mol Ther Methods Clin Dev, 17, 378-392
DOI 10.1016/j.omtm.2020.01.007, PubMed 32128342
Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity
EMBO J, 40 (5), e106228
DOI 10.15252/embj.2020106228, PubMed 33258165
Intracellular neutralisation of rotavirus by VP6-specific IgG
PLoS Pathog, 16 (8), e1008732
DOI 10.1371/journal.ppat.1008732, PubMed 32750093
Systemic Inflammation Persists the First Year after Mild Traumatic Brain Injury: Results from the Prospective Trondheim Mild Traumatic Brain Injury Study
J Neurotrauma, 37 (19), 2120-2130
DOI 10.1089/neu.2019.6963, PubMed 32326805
Methionine- and Choline-Deficient Diet Enhances Adipose Lipolysis and Leptin Release in aP2-Cre Fatp4-Knockout Mice
Mol Nutr Food Res, 64 (22), e2000361
DOI 10.1002/mnfr.202000361, PubMed 32991778
B cell tolerance and antibody production to the celiac disease autoantigen transglutaminase 2
J Exp Med, 217 (2)
DOI 10.1084/jem.20190860, PubMed 31727780
TLR8 and complement C5 induce cytokine release and thrombin activation in human whole blood challenged with Gram-positive bacteria
J Leukoc Biol, 107 (4), 673-683
DOI 10.1002/JLB.3A0120-114R, PubMed 32083344
Distinct Pattern of Endoplasmic Reticulum Protein Processing and Extracellular Matrix Proteins in Functioning and Silent Corticotroph Pituitary Adenomas
Cancers (Basel), 12 (10)
DOI 10.3390/cancers12102980, PubMed 33066652
NETs analysed by novel calprotectin-based assays in blood donors and patients with multiple myeloma or rheumatoid arthritis: A pilot study
Scand J Immunol, 91 (5), e12870
DOI 10.1111/sji.12870, PubMed 32034957
Targeting Antigens to Different Receptors on Conventional Type 1 Dendritic Cells Impacts the Immune Response
J Immunol, 205 (3), 661-673
DOI 10.4049/jimmunol.1901119, PubMed 32591401
Fecal microbiota transplantation in systemic sclerosis: A double-blind, placebo-controlled randomized pilot trial
PLoS One, 15 (5), e0232739
DOI 10.1371/journal.pone.0232739, PubMed 32437393
In vivo Cell Tracking Using Non-invasive Imaging of Iron Oxide-Based Particles with Particular Relevance for Stem Cell-Based Treatments of Neurological and Cardiac Disease
Mol Imaging Biol, 22 (6), 1469-1488
DOI 10.1007/s11307-019-01440-4, PubMed 31802361
Quantitative Changes in the Mitochondrial Proteome of Cerebellar Synaptosomes From Preclinical Cystatin B-Deficient Mice
Front Mol Neurosci, 13, 570640
DOI 10.3389/fnmol.2020.570640, PubMed 33281550
Anterior segment parameters associated with extramuscular manifestations in polymyositis and dermatomyositis
Int J Ophthalmol, 13 (9), 1443-1450
DOI 10.18240/ijo.2020.09.17, PubMed 32953585
Complement Activation in 22q11.2 Deletion Syndrome
J Clin Immunol, 40 (3), 515-523
DOI 10.1007/s10875-020-00766-x, PubMed 32152940
Induction of Cross-Reactive and Protective Antibody Responses After DNA Vaccination With MHCII-Targeted Stem Domain From Influenza Hemagglutinin
Front Immunol, 11, 431
DOI 10.3389/fimmu.2020.00431, PubMed 32269566
Can medicinal mushrooms have prophylactic or therapeutic effect against COVID-19 and its pneumonic superinfection and complicating inflammation?
Scand J Immunol, 93 (1), e12937
DOI 10.1111/sji.12937, PubMed 32657436
Antitumor, Anti-Inflammatory and Antiallergic Effects of Agaricus blazei Mushroom Extract and the Related Medicinal Basidiomycetes Mushrooms, Hericium erinaceus and Grifola frondosa: A Review of Preclinical and Clinical Studies
Nutrients, 12 (5)
DOI 10.3390/nu12051339, PubMed 32397163
Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients
Proc Natl Acad Sci U S A, 117 (40), 25018-25025
DOI 10.1073/pnas.2010540117, PubMed 32943538
Anti-inflammatory effects of non-statin low-density lipoprotein cholesterol-lowering drugs: an unused potential?
Scand Cardiovasc J, 54 (5), 274-279
DOI 10.1080/14017431.2020.1775878, PubMed 32500743
FcRn is a CD32a coreceptor that determines susceptibility to IgG immune complex-driven autoimmunity
J Exp Med, 217 (10)
DOI 10.1084/jem.20200359, PubMed 32658257
CD4+ T-cell killing of multiple myeloma cells is mediated by resident bone marrow macrophages
Blood Adv, 4 (12), 2595-2605
DOI 10.1182/bloodadvances.2020001434, PubMed 32544236
COVID-19: Symptoms, course of illness and use of clinical scoring systems for the first 42 patients admitted to a Norwegian local hospital
Tidsskr Nor Laegeforen, 140 (7)
DOI 10.4045/tidsskr.20.0301, PubMed 32378844
HLA and sleep parameter associations in post-H1N1 narcolepsy type 1 patients and first-degree relatives
Sleep, 43 (3)
DOI 10.1093/sleep/zsz239, PubMed 31606740
CD14 inhibition improves survival and attenuates thrombo-inflammation and cardiopulmonary dysfunction in a baboon model of Escherichia coli sepsis
J Thromb Haemost, 19 (2), 429-443
DOI 10.1111/jth.15162, PubMed 33174372
A Small-Molecule Tankyrase Inhibitor Reduces Glioma Stem Cell Proliferation and Sphere Formation
Cancers (Basel), 12 (6)
DOI 10.3390/cancers12061630, PubMed 32575464
Pancreatic cancer cells show lower oleic acid oxidation and their conditioned medium inhibits oleic acid oxidation in human myotubes
Pancreatology, 20 (4), 676-682
DOI 10.1016/j.pan.2020.04.014, PubMed 32360002
PD-1 Blockade Reinvigorates Bone Marrow CD8+ T Cells from Patients with Multiple Myeloma in the Presence of TGFβ Inhibitors
Clin Cancer Res, 26 (7), 1644-1655
DOI 10.1158/1078-0432.CCR-19-0267, PubMed 31941832
Human Leukocyte Antigen alleles associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Sci Rep, 10 (1), 5267
DOI 10.1038/s41598-020-62157-x, PubMed 32210306
NHDL, a recombinant VL/VH hybrid antibody control for IgG2/4 antibodies
MAbs, 12 (1), 1686319
DOI 10.1080/19420862.2019.1686319, PubMed 31671278
Disease-specific phenotypes in iPSC-derived neural stem cells with POLG mutations
EMBO Mol Med, 12 (10), e12146
DOI 10.15252/emmm.202012146, PubMed 32840960
N-acetylcysteine amide ameliorates mitochondrial dysfunction and reduces oxidative stress in hiPSC-derived dopaminergic neurons with POLG mutation
Exp Neurol, 337, 113536
DOI 10.1016/j.expneurol.2020.113536, PubMed 33264635
Absence of NLRP3 Inflammasome in Hematopoietic Cells Reduces Adverse Remodeling After Experimental Myocardial Infarction
JACC Basic Transl Sci, 5 (12), 1210-1224
DOI 10.1016/j.jacbts.2020.09.013, PubMed 33426377
Gut Microbiota-Dependent Trimethylamine N-Oxide Associates With Inflammation in Common Variable Immunodeficiency
Front Immunol, 11, 574500
DOI 10.3389/fimmu.2020.574500, PubMed 33042155
Function and Regulation of Noncanonical Caspase-4/5/11 Inflammasome
J Immunol, 204 (12), 3063-3069
DOI 10.4049/jimmunol.2000373, PubMed 32513874
Polymorphisms in human immunoglobulin heavy chain variable genes and their upstream regions
Nucleic Acids Res, 48 (10), 5499-5510
DOI 10.1093/nar/gkaa310, PubMed 32365177
Complement in sepsis-when science meets clinics
FEBS Lett, 594 (16), 2621-2632
DOI 10.1002/1873-3468.13881, PubMed 32621378
National Early Warning Score 2 (NEWS2) on admission predicts severe disease and in-hospital mortality from Covid-19 - a prospective cohort study
Scand J Trauma Resusc Emerg Med, 28 (1), 66
DOI 10.1186/s13049-020-00764-3, PubMed 32660623
An intact C-terminal end of albumin is required for its long half-life in humans
Commun Biol, 3 (1), 181
DOI 10.1038/s42003-020-0903-7, PubMed 32313072
Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis
EBioMedicine, 60, 102985
DOI 10.1016/j.ebiom.2020.102985, PubMed 32927275
A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity
J Immunol, 205 (8), 2287-2300
DOI 10.4049/jimmunol.2000752, PubMed 32938727
Sjögren syndrome/scleroderma autoantigen 1 is a direct Tankyrase binding partner in cancer cells
Commun Biol, 3 (1), 123
DOI 10.1038/s42003-020-0851-2, PubMed 32170109
Intravenous Cyclophosphamide in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. An Open-Label Phase II Study
Front Med (Lausanne), 7, 162
DOI 10.3389/fmed.2020.00162, PubMed 32411717
Mechanical loading prevents bone destruction and exerts anti-tumor effects in the MOPC315.BM.Luc model of myeloma bone disease
Acta Biomater, 119, 247-258
DOI 10.1016/j.actbio.2020.10.041, PubMed 33130307
Growth Mode and Physiological State of Cells Prior to Biofilm Formation Affect Immune Evasion and Persistence of Staphylococcus aureus
Microorganisms, 8 (1)
DOI 10.3390/microorganisms8010106, PubMed 31940921
Platelets mediate serological memory to neutralize viruses in vitro and in vivo
Blood Adv, 4 (16), 3971-3976
DOI 10.1182/bloodadvances.2020001786, PubMed 32841338
Complement component C3 and the TLR co-receptor CD14 are not involved in angiotensin II induced cardiac remodelling
Biochem Biophys Res Commun, 523 (4), 867-873
DOI 10.1016/j.bbrc.2020.01.018, PubMed 31955888
Sputter Deposition of Titanium on Poly(Methyl Methacrylate) Enhances Corneal Biocompatibility
Transl Vis Sci Technol, 9 (13), 41
DOI 10.1167/tvst.9.13.41, PubMed 33442495
Avoiding ambient air in test tubes during incubations of human whole-blood minimizes complement background activation
J Immunol Methods, 487, 112876
DOI 10.1016/j.jim.2020.112876, PubMed 33031792
Second-Tier Next Generation Sequencing Integrated in Nationwide Newborn Screening Provides Rapid Molecular Diagnostics of Severe Combined Immunodeficiency
Front Immunol, 11, 1417
DOI 10.3389/fimmu.2020.01417, PubMed 32754152
[Oncorheumatology: relationship between malignancies and musculoskeletal diseases]
Orv Hetil, 161 (28), 1151-1165
DOI 10.1556/650.2020.31800, PubMed 32609623
Eight pillars of oncorheumatology: Crossroads between malignancies and musculoskeletal diseases
Autoimmun Rev, 19 (11), 102658
DOI 10.1016/j.autrev.2020.102658, PubMed 32942035
Respiratory chain signalling is essential for adaptive remodelling following cardiac ischaemia
J Cell Mol Med, 24 (6), 3534-3548
DOI 10.1111/jcmm.15043, PubMed 32040259
Maternal Microchimerism in Cord Blood and Risk of Celiac Disease in Childhood
J Pediatr Gastroenterol Nutr, 71 (3), 321-327
DOI 10.1097/MPG.0000000000002811, PubMed 32833392
A molecular basis for the T cell response in HLA-DQ2.2 mediated celiac disease
Proc Natl Acad Sci U S A, 117 (6), 3063-3073
DOI 10.1073/pnas.1914308117, PubMed 31974305
Onecut-dependent Nkx6.2 transcription factor expression is required for proper formation and activity of spinal locomotor circuits
Sci Rep, 10 (1), 996
DOI 10.1038/s41598-020-57945-4, PubMed 31969659
Cardiorespiratory fitness on a treadmill in an adult cystic fibrosis population
BMJ Open Sport Exerc Med, 6 (1), e000765
DOI 10.1136/bmjsem-2020-000765, PubMed 32843991
Choice of immunoassay to evaluate porcine cytokine levels
Vet Immunol Immunopathol, 230, 110129
DOI 10.1016/j.vetimm.2020.110129, PubMed 33059181
Unrestrained ESCRT-III drives micronuclear catastrophe and chromosome fragmentation
Nat Cell Biol, 22 (7), 856-867
DOI 10.1038/s41556-020-0537-5, PubMed 32601372
Tankyrase inhibition ameliorates lipid disorder via suppression of PGC-1α PARylation in db/db mice
Int J Obes (Lond), 44 (8), 1691-1702
DOI 10.1038/s41366-020-0573-z, PubMed 32317752
Repurposed Antiviral Drugs for Covid-19 - Interim WHO Solidarity Trial Results
N Engl J Med, 384 (6), 497-511
DOI 10.1056/NEJMoa2023184, PubMed 33264556
Preclinical Lead Optimization of a 1,2,4-Triazole Based Tankyrase Inhibitor
J Med Chem, 63 (13), 6834-6846
DOI 10.1021/acs.jmedchem.0c00208, PubMed 32511917
Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models
Commun Biol, 3 (1), 196
DOI 10.1038/s42003-020-0916-2, PubMed 32332858
Soluble collectin-12 mediates C3-independent docking of properdin that activates the alternative pathway of complement
Elife, 9
DOI 10.7554/eLife.60908, PubMed 32909942
An Early Myeloma Bone Disease Model in Skeletally Mature Mice as a Platform for Biomaterial Characterization of the Extracellular Matrix
J Oncol, 2020, 3985315
DOI 10.1155/2020/3985315, PubMed 32684931
Intestinal Epithelial Cells Express Immunomodulatory ISG15 During Active Ulcerative Colitis and Crohn's Disease
J Crohns Colitis, 14 (7), 920-934
DOI 10.1093/ecco-jcc/jjaa022, PubMed 32020185