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Publications (original articles or review articles) published in 2022 from OUS - Department of Immunology (Div LabMed)

49 publications found

Akbar R, Bashour H, Rawat P, Robert PA, Smorodina E, Cotet TS, Flem-Karlsen K, Frank R, Mehta BB, Vu MH, Zengin T, Gutierrez-Marcos J, Lund-Johansen F, Andersen JT, Greiff V (2022)
Progress and challenges for the machine learning-based design of fit-for-purpose monoclonal antibodies
MAbs, 14 (1), 2008790
DOI 10.1080/19420862.2021.2008790, PubMed 35293269

Akbar R, Robert PA, Weber CR, Widrich M, Frank R, Pavlović M, Scheffer L, Chernigovskaya M, Snapkov I, Slabodkin A, Mehta BB, Miho E, Lund-Johansen F, Andersen JT, Hochreiter S, Hobæk Haff I, Klambauer G, Sandve GK, Greiff V (2022)
In silico proof of principle of machine learning-based antibody design at unconstrained scale
MAbs, 14 (1), 2031482
DOI 10.1080/19420862.2022.2031482, PubMed 35377271

Anda EE, Braaten T, Borch KB, Nøst TH, Chen SLF, Lukic M, Lund E, Forland F, Leon DA, Winje BA, Kran AB, Kalager M, Johansen FL, Sandanger TM (2022)
Seroprevalence of antibodies against SARS-CoV-2 in the adult population during the pre-vaccination period, Norway, winter 2020/21
Euro Surveill, 27 (13)
DOI 10.2807/1560-7917.ES.2022.27.13.2100376, PubMed 35362405

Bekri S, Rodney-Sandy R, Gruenstein D, Mei A, Bogen B, Castle J, Levey D, Cho HJ (2022)
Neoantigen vaccine-induced CD4 T cells confer protective immunity in a mouse model of multiple myeloma through activation of CD8 T cells against non-vaccine, tumor-associated antigens
J Immunother Cancer, 10 (2)
DOI 10.1136/jitc-2021-003572, PubMed 35190376

Bollineni RC, Tran TT, Lund-Johansen F, Olweus J (2022)
Chasing neoantigens; invite naïve T cells to the party
Curr Opin Immunol, 75, 102172
DOI 10.1016/j.coi.2022.102172, PubMed 35279483

Busek M, Aizenshtadt A, Amirola-Martinez M, Delon L, Krauss S (2022)
Academic User View: Organ-on-a-Chip Technology
Biosensors (Basel), 12 (2)
DOI 10.3390/bios12020126, PubMed 35200386

Christophersen A, Dahal-Koirala S, Chlubnová M, Jahnsen J, Lundin KEA, Sollid LM (2022)
Phenotype-Based Isolation of Antigen-Specific CD4⁺ T Cells in Autoimmunity: A Study of Celiac Disease
Adv Sci (Weinh), 9 (10), e2104766
DOI 10.1002/advs.202104766, PubMed 35119226

Ciacchi L, Farenc C, Dahal-Koirala S, Petersen J, Sollid LM, Reid HH, Rossjohn J (2022)
Structural basis of T cell receptor specificity and cross-reactivity of two HLA-DQ2.5-restricted gluten epitopes in celiac disease
J Biol Chem, 298 (3), 101619
DOI 10.1016/j.jbc.2022.101619, PubMed 35065967

Dahal-Koirala S, Balaban G, Neumann RS, Scheffer L, Lundin KEA, Greiff V, Sollid LM, Qiao SW, Sandve GK (2022)
TCRpower: quantifying the detection power of T-cell receptor sequencing with a novel computational pipeline calibrated by spike-in sequences
Brief Bioinform, 23 (2)
DOI 10.1093/bib/bbab566, PubMed 35062022

Emblem Å, Knutsen E, Jørgensen TE, Fure H, Johansen SD, Brekke OL, Mollnes TE, Karlsen BO (2022)
Blood Transcriptome Analysis of Septic Patients Reveals a Long Non-Coding Alu-RNA in the Complement C5a Receptor 1 Gene
Noncoding RNA, 8 (2)
DOI 10.3390/ncrna8020024, PubMed 35447887

Foss S, Jonsson A, Bottermann M, Watkinson R, Lode HE, McAdam MB, Michaelsen TE, Sandlie I, James LC, Andersen JT (2022)
Potent TRIM21 and complement-dependent intracellular antiviral immunity requires the IgG3 hinge
Sci Immunol, 7 (70), eabj1640
DOI 10.1126/sciimmunol.abj1640, PubMed 35486676

Giliberto M, Thimiri Govinda Raj DB, Cremaschi A, Skånland SS, Gade A, Tjønnfjord GE, Schjesvold F, Munthe LA, Taskén K (2022)
Ex vivo drug sensitivity screening in multiple myeloma identifies drug combinations that act synergistically
Mol Oncol, 16 (6), 1241-1258
DOI 10.1002/1878-0261.13191, PubMed 35148457

Grevys A, Frick R, Mester S, Flem-Karlsen K, Nilsen J, Foss S, Sand KMK, Emrich T, Fischer JAA, Greiff V, Sandlie I, Schlothauer T, Andersen JT (2022)
Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life
iScience, 25 (2), 103746
DOI 10.1016/j.isci.2022.103746, PubMed 35118359

Hajdarevic R, Lande A, Mehlsen J, Rydland A, Sosa DD, Strand EB, Mella O, Pociot F, Fluge Ø, Lie BA, Viken MK (2022)
Genetic association study in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) identifies several potential risk loci
Brain Behav Immun, 102, 362-369
DOI 10.1016/j.bbi.2022.03.010, PubMed 35318112

Harrison GF, Leaton LA, Harrison EA, Kichula KM, Viken MK, Shortt J, Gignoux CR, Lie BA, Vukcevic D, Leslie S, Norman PJ (2022)
Allele imputation for the killer cell immunoglobulin-like receptor KIR3DL1/S1
PLoS Comput Biol, 18 (2), e1009059
DOI 10.1371/journal.pcbi.1009059, PubMed 35192601

Heldal TF, Åsberg A, Ueland T, Reisaeter AV, Pischke SE, Mollnes TE, Aukrust P, Hartmann A, Heldal K, Jenssen T (2022)
Inflammation in the early phase after kidney transplantation is associated with increased long-term all-cause mortality
Am J Transplant (in press)
DOI 10.1111/ajt.17047, PubMed 35352462

Hribkova H, Svoboda O, Bartecku E, Zelinkova J, Horinkova J, Lacinova L, Piskacek M, Lipovy B, Provaznik I, Glover JC, Kasparek T, Sun YM (2022)
Clozapine Reverses Dysfunction of Glutamatergic Neurons Derived From Clozapine-Responsive Schizophrenia Patients
Front Cell Neurosci, 16, 830757
DOI 10.3389/fncel.2022.830757, PubMed 35281293

Huse C, Anstensrud AK, Michelsen AE, Ueland T, Broch K, Woxholt S, Yang K, Sharma K, Tøllefsen IM, Bendz B, Amundsen BH, Damås JK, Berg ES, Bjørkelund E, Quiles-Jiménez A, Bjerkeli V, Bendz C, Kleveland O, Stensaeth KH, Opdahl A, Kløw NE, Andersen GØ, Wiseth R, Halvorsen B, Gullestad L et al. (2022)
Interleukin-6 inhibition in ST-elevation myocardial infarction: Immune cell profile in the randomised ASSAIL-MI trial
EBioMedicine, 80, 104013 (in press)
DOI 10.1016/j.ebiom.2022.104013, PubMed 35504178

Keresztes G, Baer M, Alfenito MR, Verwoerd TC, Kovalchuk A, Wiebe MG, Andersen TK, Saloheimo M, Tchelet R, Kensinger R, Grødeland G, Emalfarb M (2022)
The Highly Productive Thermothelomyces heterothallica C1 Expression System as a Host for Rapid Development of Influenza Vaccines
Vaccines (Basel), 10 (2)
DOI 10.3390/vaccines10020148, PubMed 35214607

König M, Torgauten HM, Tran TT, Holmøy T, Vaage JT, Lund-Johansen F, Nygaard GO (2022)
Immunogenicity and Safety of a Third SARS-CoV-2 Vaccine Dose in Patients With Multiple Sclerosis and Weak Immune Response After COVID-19 Vaccination
JAMA Neurol, 79 (3), 307-309
DOI 10.1001/jamaneurol.2021.5109, PubMed 35072702

Li J, Li YR, Glessner JT, Yang J, March ME, Kao C, Vaccaro CN, Bradfield JP, Li J, Mentch FD, Qu H, Qi X, Chang X, Hou C, Abrams DJ, Qiu H, Wei Z, Connolly JJ, Wang F, Snyder J, Flatø B, Thompson SD, Langefeld CD, Lie BA, Munro JE et al. (2022)
Identification of Novel Loci Shared by Juvenile Idiopathic Arthritis Subtypes through Integrative Genetic Analysis
Arthritis Rheumatol (in press)
DOI 10.1002/art.42129, PubMed 35347896

Li J, Zaslavsky M, Su Y, Guo J, Sikora MJ, van Unen V, Christophersen A, Chiou SH, Chen L, Li J, Ji X, Wilhelmy J, McSween AM, Palanski BA, Mallajosyula VVA, Bracey NA, Dhondalay GKR, Bhamidipati K, Pai J, Kipp LB, Dunn JE, Hauser SL, Oksenberg JR, Satpathy AT, Robinson WH et al. (2022)
KIR⁺CD8⁺ T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19
Science, 376 (6590), eabi9591
DOI 10.1126/science.abi9591, PubMed 35258337

Lindeman I, Polak J, Qiao SW, Holmøy T, Høglund RA, Vartdal F, Berg-Hansen P, Sollid LM, Lossius A (2022)
Stereotyped B-cell responses are linked to IgG constant region polymorphisms in multiple sclerosis
Eur J Immunol, 52 (4), 550-565
DOI 10.1002/eji.202149576, PubMed 35094395

Lindstad CB, du Pré MF, Stamnaes J, Sollid LM (2022)
Injection of prototypic celiac anti-transglutaminase 2 antibodies in mice does not cause enteropathy
PLoS One, 17 (4), e0266543
DOI 10.1371/journal.pone.0266543, PubMed 35385534

Lund Berven L, Selvakumar J, Havdal L, Stiansen-Sonerud T, Einvik G, Leegaard TM, Tjade T, Michelsen AE, Mollnes TE, Wyller VBB (2022)
Inflammatory Markers, Pulmonary Function, and Clinical Symptoms in Acute COVID-19 Among Non-Hospitalized Adolescents and Young Adults
Front Immunol, 13, 837288
DOI 10.3389/fimmu.2022.837288, PubMed 35222429

Madsen-Østerbye J, Abdelhalim M, Baudement MO, Collas P (2022)
Local euchromatin enrichment in lamina-associated domains anticipates their repositioning in the adipogenic lineage
Genome Biol, 23 (1), 91
DOI 10.1186/s13059-022-02662-6, PubMed 35410387

Medeiros PMC, Schjalm C, Christiansen D, Sokolova M, Pischke SE, Würzner R, Mollnes TE, Barratt-Due A (2022)
Vitamin C, Hydrocortisone, and the Combination Thereof Significantly Inhibited Two of Nine Inflammatory Markers Induced by Escherichia Coli But Not by Staphylococcus Aureus - When Incubated in Human Whole Blood
Shock, 57 (1), 72-80
DOI 10.1097/SHK.0000000000001834, PubMed 34265830

Mollnes TE, Storm BS, Brekke OL, Nilsson PH, Lambris JD (2022)
Application of the C3 inhibitor compstatin in a human whole blood model designed for complement research - 20 years of experience and future perspectives
Semin Immunol, 101604 (in press)
DOI 10.1016/j.smim.2022.101604, PubMed 35570131

Mørtberg TV, Zhi H, Vidarsson G, Foss S, Lissenberg-Thunnissen S, Wuhrer M, Michaelsen TE, Skogen B, Stuge TB, Andersen JT, Newman PJ, Ahlen MT (2022)
Prevention of Fetal/Neonatal Alloimmune Thrombocytopenia in Mice: Biochemical and Cell Biological Characterization of Isoforms of a Human Monoclonal Antibody
Immunohorizons, 6 (1), 90-103
DOI 10.4049/immunohorizons.2100097, PubMed 35074850

Nguyen THP, Hokstad I, Fagerland MW, Mollnes TE, Hollan I, Feinberg MW, Hjeltnes G, Eilertsen GØ, Mikkelsen K, Agewall S (2022)
Antirheumatic therapy is associated with reduced complement activation in rheumatoid arthritis
PLoS One, 17 (2), e0264628
DOI 10.1371/journal.pone.0264628, PubMed 35213675

Nielsen EW, Miller Y, Brekke OL, Grond J, Duong AH, Fure H, Ludviksen JK, Pettersen K, Reubsaet L, Solberg R, Johansen HT, Mollnes TE (2022)
A Novel Porcine Model of Ischemia-Reperfusion Injury After Cross-Clamping the Thoracic Aorta Revealed Substantial Cardiopulmonary, Thromboinflammatory and Biochemical Changes Without Effect of C1-Inhibitor Treatment
Front Immunol, 13, 852119
DOI 10.3389/fimmu.2022.852119, PubMed 35432333

Paulsen J, Collas P (2022)
Modeling the 3D Genome Using Hi-C and Nuclear Lamin-Genome Contacts
Methods Mol Biol, 2301, 337-352
DOI 10.1007/978-1-0716-1390-0_18, PubMed 34415545

Quach HQ, Johnson C, Ekholt K, Islam R, Mollnes TE, Nilsson PH (2022)
Platelet-Depletion of Whole Blood Reveals That Platelets Potentiate the Release of IL-8 From Leukocytes Into Plasma in a Thrombin-Dependent Manner
Front Immunol, 13, 865386
DOI 10.3389/fimmu.2022.865386, PubMed 35444648

Riise J, Meyer S, Blaas I, Chopra A, Tran TT, Delic-Sarac M, Hestdalen ML, Brodin E, Rustad EH, Dai KZ, Vaage JT, Nissen-Meyer LSH, Sund F, Wader KF, Bjornevik AT, Meyer PA, Nygaard GO, König M, Smeland S, Lund-Johansen F, Olweus J, Kolstad A (2022)
Rituximab-treated patients with lymphoma develop strong CD8 T-cell responses following COVID-19 vaccination
Br J Haematol (in press)
DOI 10.1111/bjh.18149, PubMed 35254660

Rotevatn TA, Elstrøm P, Greve-Isdahl M, Surén P, Johansen TKB, Astrup E (2022)
School Closure Versus Targeted Control Measures for SARS-CoV-2 Infection
Pediatrics, 149 (5)
DOI 10.1542/peds.2021-055071, PubMed 35274128

Saevarsdottir S, Stefansdottir L, Sulem P, Thorleifsson G, Ferkingstad E, Rutsdottir G, Glintborg B, Westerlind H, Grondal G, Loft IC, Sorensen SB, Lie BA, Brink M, Ärlestig L, Arnthorsson AO, Baecklund E, Banasik K, Bank S, Bjorkman LI, Ellingsen T, Erikstrup C, Frei O, Gjertsson I, Gudbjartsson DF, Gudjonsson SA et al. (2022)
Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset
Ann Rheum Dis (in press)
DOI 10.1136/annrheumdis-2021-221754, PubMed 35470158

Skånland SS, Inngjerdingen M, Bendiksen H, York J, Spetalen S, Munthe LA, Tjønnfjord GE (2022)
Functional testing of relapsed chronic lymphocytic leukemia guides precision medicine and maps response and resistance mechanisms. An index case
Haematologica (in press)
DOI 10.3324/haematol.2021.280393, PubMed 35236056

Sollid LM (2022)
Epstein-Barr virus as a driver of multiple sclerosis
Sci Immunol, 7 (70), eabo7799
DOI 10.1126/sciimmunol.abo7799, PubMed 35363541

Soloey-Nilsen H, Nygaard-Odeh K, Kristiansen MG, Brekke OL, Mollnes TE, Reitan SK, Oiesvold T (2022)
Association between brain-derived neurotropic factor (BDNF), high-sensitivity C-reactive protein (hs-CRP) and psychiatric symptoms in medicated and unmedicated patients
BMC Psychiatry, 22 (1), 84
DOI 10.1186/s12888-022-03744-2, PubMed 35114967

Storm BS, Ludviksen JK, Christiansen D, Fure H, Pettersen K, Landsem A, Nilsen BA, Dybwik K, Braaten T, Nielsen EW, Mollnes TE (2022)
Venous Air Embolism Activates Complement C3 Without Corresponding C5 Activation and Trigger Thromboinflammation in Pigs
Front Immunol, 13, 839632
DOI 10.3389/fimmu.2022.839632, PubMed 35371063

Syversen SW, Jyssum I, Tveter AT, Tran TT, Sexton J, Provan SA, Mjaaland S, Warren DJ, Kvien TK, Grødeland G, Nissen-Meyer LSH, Ricanek P, Chopra A, Andersson AM, Kro GB, Jahnsen J, Munthe LA, Haavardsholm EA, Vaage JT, Lund-Johansen F, Jørgensen KK, Goll GL (2022)
Immunogenicity and Safety of Standard and Third Dose SARS-CoV-2 Vaccination in Patients on Immunosuppressive Therapy
Arthritis Rheumatol (in press)
DOI 10.1002/art.42153, PubMed 35507355

Sørensen K, Stjern HE, Karlsen BAG, Tomter G, Ystad I, Herud I, Baevre MS, Llohn AH, Akkök ÇA (2022)
Following targeted routine antenatal anti-D prophylaxis, almost half of the pregnant women had undetectable anti-D prophylaxis at delivery
Acta Obstet Gynecol Scand, 101 (4), 431-440
DOI 10.1111/aogs.14328, PubMed 35224728

Tesfaye DY, Bobic S, Lysén A, Huszthy PC, Gudjonsson A, Braathen R, Bogen B, Fossum E (2022)
Targeting Xcr1 on Dendritic Cells Rapidly Induce Th1-Associated Immune Responses That Contribute to Protection Against Influenza Infection
Front Immunol, 13, 752714
DOI 10.3389/fimmu.2022.752714, PubMed 35296089

Udugama M, Vinod B, Chan FL, Hii L, Garvie A, Collas P, Kalitsis P, Steer D, Das PP, Tripathi P, Mann JR, Voon HPJ, Wong LH (2022)
Histone H3.3 phosphorylation promotes heterochromatin formation by inhibiting H3K9/K36 histone demethylase
Nucleic Acids Res (in press)
DOI 10.1093/nar/gkac259, PubMed 35451487

Ueland T, Hausberg I, Mørtberg TV, Dahl TB, Lerum TV, Michelsen A, Ranheim T, Nezvalova Henriksen K, Dyrhol-Riise AM, Holme PA, Aaløkken TM, Skjønsberg OH, Barratt-Due A, Ahlén MT, Aukrust P, Halvorsen B (2022)
Anti-PF4/polyanion antibodies in COVID-19 patients are associated with disease severity and pulmonary pathology
Platelets, 33 (4), 640-644
DOI 10.1080/09537104.2022.2042238, PubMed 35225150

Vaksdal HH, Grødeland G (2022)
Efficacy of three doses of COVID-19 vaccine
Tidsskr Nor Laegeforen, 142 (5)
DOI 10.4045/tidsskr.22.0096, PubMed 35324133

Vestad B, Ueland T, Lerum TV, Dahl TB, Holm K, Barratt-Due A, Kåsine T, Dyrhol-Riise AM, Stiksrud B, Tonby K, Hoel H, Olsen IC, Henriksen KN, Tveita A, Manotheepan R, Haugli M, Eiken R, Berg Å, Halvorsen B, Lekva T, Ranheim T, Michelsen AE, Kildal AB, Johannessen A, Thoresen L et al. (2022)
Respiratory dysfunction three months after severe COVID-19 is associated with gut microbiota alterations
J Intern Med, 291 (6), 801-812
DOI 10.1111/joim.13458, PubMed 35212063

Witczak BN, Schwartz T, Barth Z, Taraldsrud E, Lund MB, Aaløkken TM, Flatø B, Sjaastad I, Sanner H (2022)
Associations between cardiac and pulmonary involvement in patients with juvenile dermatomyositis-a cross-sectional study
Rheumatol Int
DOI 10.1007/s00296-021-05071-3, PubMed 34984516

Zakrzewicz A, Würth C, Beckert B, Feldhoff S, Vanderheyden K, Foss S, Andersen JT, Haard H, Verheesen P, Bobkov V, Tikkanen R (2022)
Stabilization of Keratinocyte Monolayer Integrity in the Presence of Anti-Desmoglein-3 Antibodies through FcRn Blockade with Efgartigimod: Novel Treatment Paradigm for Pemphigus?
Cells, 11 (6)
DOI 10.3390/cells11060942, PubMed 35326398