Publications (original articles or review articles) published in 2023 from OUS - Department of Immunology (Div LabMed)
104 publications found
Adipose-Derived Stromal Cells Preserve Pancreatic Islet Function in a Transplantable 3D Bioprinted Scaffold
Adv Healthc Mater, 12 (32), e2300640
DOI 10.1002/adhm.202300640, PubMed 37781993
Expression of transglutaminase 2 in human gut epithelial cells: Implications for coeliac disease
PLoS One, 18 (6), e0287662
DOI 10.1371/journal.pone.0287662, PubMed 37368893
The neoepitope of the complement C5b-9 Membrane Attack Complex is formed by proximity of adjacent ancillary regions of C9
Commun Biol, 6 (1), 42
DOI 10.1038/s42003-023-04431-y, PubMed 36639734
Cellular and Genomic Features of Muscle Differentiation from Isogenic Fibroblasts and Myoblasts
Cells, 12 (15)
DOI 10.3390/cells12151995, PubMed 37566074
A pan-SARS-CoV-2-specific soluble angiotensin-converting enzyme 2-albumin fusion engineered for enhanced plasma half-life and needle-free mucosal delivery
PNAS Nexus, 2 (12), pgad403
DOI 10.1093/pnasnexus/pgad403, PubMed 38077689
Wnt/β-Catenin Signaling Activation Induces Differentiation in Human Limbal Epithelial Stem Cells Cultured Ex Vivo
Biomedicines, 11 (7)
DOI 10.3390/biomedicines11071829, PubMed 37509479
Dual inhibition of complement C5 and CD14 attenuates inflammation in a cord blood model
Pediatr Res, 94 (2), 512-519
DOI 10.1038/s41390-023-02489-2, PubMed 36725909
HLA-DQ2 is associated with anti-drug antibody formation to infliximab in patients with immune-mediated inflammatory diseases
J Intern Med, 293 (5), 648-655
DOI 10.1111/joim.13616, PubMed 36843323
Neisseria meningitidis accumulate in large organs during meningococcal sepsis
Front Cell Infect Microbiol, 13, 1298360
DOI 10.3389/fcimb.2023.1298360, PubMed 38089821
Pump-less, recirculating organ-on-a-chip (rOoC) platform
Lab Chip, 23 (4), 591-608
DOI 10.1039/d2lc00919f, PubMed 36655405
Escherichia coli-induced inflammatory responses are temperature-dependent in human whole blood ex vivo
Mol Immunol, 157, 70-77
DOI 10.1016/j.molimm.2023.03.006, PubMed 37001293
Identification of gluten T cell epitopes driving celiac disease
Sci Adv, 9 (4), eade5800
DOI 10.1126/sciadv.ade5800, PubMed 36696493
Lipopolysaccharide Primes Human Macrophages for Noncanonical Inflammasome-Induced Extracellular Vesicle Secretion
J Immunol, 210 (3), 322-334
DOI 10.4049/jimmunol.2200444, PubMed 36525001
Functional Analysis of a Novel Complement C5a Receptor 1-Blocking Monoclonal Antibody
J Innate Immun, 15 (1), 836-849
DOI 10.1159/000535084, PubMed 37952515
Bacterial Brain Abscesses Expand Despite Effective Antibiotic Treatment: A Process Powered by Osmosis Due to Neutrophil Cell Death
Neurosurgery, 94 (5), 1079-87 (in press)
DOI 10.1227/neu.0000000000002792, PubMed 38084989
Separate Gut Plasma Cell Populations Produce Auto-Antibodies against Transglutaminase 2 and Transglutaminase 3 in Dermatitis Herpetiformis
Adv Sci (Weinh), 10 (25), e2300401
DOI 10.1002/advs.202300401, PubMed 37424036
XCR1+ DCs are critical for T cell-mediated immunotherapy of chronic viral infections
Cell Rep, 42 (2), 112123
DOI 10.1016/j.celrep.2023.112123, PubMed 36795562
Scandiatransplant Exchange Program (STEP): Development and Results From an International Kidney Exchange Program
Transplant Direct, 9 (11), e1549
DOI 10.1097/TXD.0000000000001549, PubMed 37854025
Application and challenges of TCR and BCR sequencing to investigate T- and B-cell clonality in elastase-induced experimental murine abdominal aortic aneurysm
Front Cardiovasc Med, 10, 1221620
DOI 10.3389/fcvm.2023.1221620, PubMed 38034381
DNase analysed by a novel competitive assay in patients with complications after ChAdOx1 nCoV-19 vaccination and in normal unvaccinated blood donors
Scand J Immunol, 98 (1), e13274
DOI 10.1111/sji.13274, PubMed 37676118
Experimental validation of immunogenic SARS-CoV-2 T cell epitopes identified by artificial intelligence
Front Immunol, 14, 1265044
DOI 10.3389/fimmu.2023.1265044, PubMed 38045681
Robust spike-specific CD4+ and CD8+ T cell responses in SARS-CoV-2 vaccinated hematopoietic cell transplantation recipients: a prospective, cohort study
Front Immunol, 14, 1210899
DOI 10.3389/fimmu.2023.1210899, PubMed 37503339
Assessing developability early in the discovery process for novel biologics
MAbs, 15 (1), 2171248
DOI 10.1080/19420862.2023.2171248, PubMed 36823021
Rapid, Cost-Efficient, Enzyme-Free Passaging of Human Pluripotent Stem Cells on Feeder Cells by Ethylenediaminetetraacetic Acid-Mediated Dis-Adhesion
J Vis Exp (197)
DOI 10.3791/63788, PubMed 37486113
A systematic safety pipeline for selection of T-cell receptors to enter clinical use
NPJ Vaccines, 8 (1), 126
DOI 10.1038/s41541-023-00713-y, PubMed 37607971
PML modulates epigenetic composition of chromatin to regulate expression of pro-metastatic genes in triple-negative breast cancer
Nucleic Acids Res, 51 (20), 11024-11039
DOI 10.1093/nar/gkad819, PubMed 37823593
Comparison between articular chondrocytes and mesenchymal stromal cells for the production of articular cartilage implants
Front Bioeng Biotechnol, 11, 1116513
DOI 10.3389/fbioe.2023.1116513, PubMed 36896010
Ocrelizumab and ofatumumab, but not rituximab, trigger complement induction in vitro
Int Immunopharmacol, 124 (Pt B), 111021
DOI 10.1016/j.intimp.2023.111021, PubMed 37816262
In vitro evaluation of iron oxide nanoparticle-induced thromboinflammatory response using a combined human whole blood and endothelial cell model
Front Immunol, 14, 1101387
DOI 10.3389/fimmu.2023.1101387, PubMed 37081885
Antibody blockade of Jagged1 attenuates choroidal neovascularization
Nat Commun, 14 (1), 3109
DOI 10.1038/s41467-023-38563-w, PubMed 37253747
Progressive mitochondrial dysfunction in cerebellar synaptosomes of cystatin B-deficient mice
Front Mol Neurosci, 16, 1175851
DOI 10.3389/fnmol.2023.1175851, PubMed 37251643
Increased thromboinflammatory load in hereditary angioedema
Clin Exp Immunol, 214 (2), 170-181
DOI 10.1093/cei/uxad091, PubMed 37561062
High plasma levels of C1-inhibitor are associated with lower risk of future venous thromboembolism
J Thromb Haemost, 21 (7), 1849-1860
DOI 10.1016/j.jtha.2023.03.024, PubMed 37003465
In vitro and ex vivo proteomics of Mycobacterium marinum biofilms and the development of biofilm-binding synthetic nanobodies
mSystems, 8 (3), e0107322
DOI 10.1128/msystems.01073-22, PubMed 37184670
Scalable production of tissue-like vascularized liver organoids from human PSCs
Exp Mol Med, 55 (9), 2005-2024
DOI 10.1038/s12276-023-01074-1, PubMed 37653039
Autoantibody binding and unique enzyme-substrate intermediate conformation of human transglutaminase 3
Nat Commun, 14 (1), 6216
DOI 10.1038/s41467-023-42004-z, PubMed 37798283
Human thymic putative CD8αα precursors exhibit a biased TCR repertoire in single cell AIRR-seq
Sci Rep, 13 (1), 17714
DOI 10.1038/s41598-023-44693-4, PubMed 37853083
Systemic inflammation early after kidney transplantation is associated with long-term graft loss: a cohort study
Front Immunol, 14, 1253991
DOI 10.3389/fimmu.2023.1253991, PubMed 37849758
A tumor microenvironment model of chronic lymphocytic leukemia enables drug sensitivity testing to guide precision medicine
Cell Death Discov, 9 (1), 125
DOI 10.1038/s41420-023-01426-w, PubMed 37055391
Humoral vaccine response and breakthrough infections in kidney transplant recipients during the COVID-19 pandemic: a nationwide cohort study
EClinicalMedicine, 60, 102035
DOI 10.1016/j.eclinm.2023.102035, PubMed 37362086
Functional SARS-CoV-2 cross-reactive CD4+ T cells established in early childhood decline with age
Proc Natl Acad Sci U S A, 120 (12), e2220320120
DOI 10.1073/pnas.2220320120, PubMed 36917669
Safe Blood Donation from Donors Using Antihypertensive Medication. A Multi-Center Retrospective Quality Study from South-East Norway
J Blood Med, 14, 337-343
DOI 10.2147/JBM.S390609, PubMed 37163174
Humoral immune response to SARS-CoV-2 vaccination in patients with inflammatory bowel disease on immunosuppressive medication: association to serum drug levels and disease type
Scand J Gastroenterol, 58 (8), 874-882
DOI 10.1080/00365521.2023.2177884, PubMed 36788656
Pharmaceutical compounding and storage of faricimab in a syringe for intravitreal injection do not impair stability and bi-specific binding properties
Int J Retina Vitreous, 9 (1), 65
DOI 10.1186/s40942-023-00507-3, PubMed 37936232
Towards optimised extracellular vesicle proteomics from cerebrospinal fluid
Sci Rep, 13 (1), 9564
DOI 10.1038/s41598-023-36706-z, PubMed 37308520
Hybrid and SARS-CoV-2-vaccine immunity in kidney transplant recipients
EBioMedicine, 97, 104833
DOI 10.1016/j.ebiom.2023.104833, PubMed 37844534
Toward real-world automated antibody design with combinatorial Bayesian optimization
Cell Rep Methods, 3 (1), 100374
DOI 10.1016/j.crmeth.2022.100374, PubMed 36814835
EMD originates from hyaluronan-induced homophilic interactions of CD44 variant-expressing MM cells under shear stress
Blood Adv, 7 (4), 508-524
DOI 10.1182/bloodadvances.2022007291, PubMed 35930695
Kidney-transplanted Adolescents-Nonadherence and Graft Outcomes During the Transition Phase: A Nationwide Analysis, 2000-2020
Transplantation, 107 (5), 1206-1212
DOI 10.1097/TP.0000000000004431, PubMed 36476728
Vasa, Piwi, and Pl10 Expression during Sexual Maturation and Asexual Reproduction in the Annelid Pristina longiseta
J Dev Biol, 11 (3)
DOI 10.3390/jdb11030034, PubMed 37606490
SENP2 knockdown in human adipocytes reduces glucose metabolism and lipid accumulation, while increases lipid oxidation
Metabol Open, 18, 100234
DOI 10.1016/j.metop.2023.100234, PubMed 37013149
Characterization of Mechanical and Cellular Effects of Rhythmic Vertical Vibrations on Adherent Cell Cultures
Bioengineering (Basel), 10 (7)
DOI 10.3390/bioengineering10070811, PubMed 37508838
Mass spectrometry reveals that oxysterols are secreted from non-alcoholic fatty liver disease induced organoids
J Steroid Biochem Mol Biol, 232, 106355
DOI 10.1016/j.jsbmb.2023.106355, PubMed 37380087
Quantitative chemometric phenotyping of three-dimensional liver organoids by Raman spectral imaging
Cell Rep Methods, 3 (4), 100440
DOI 10.1016/j.crmeth.2023.100440, PubMed 37159662
Interplay between Cultured Human Osteoblastic and Skeletal Muscle Cells: Effects of Conditioned Media on Glucose and Fatty Acid Metabolism
Biomedicines, 11 (11)
DOI 10.3390/biomedicines11112908, PubMed 38001909
Disruption of the sialic acid/Siglec-9 axis improves antibody-mediated neutrophil cytotoxicity towards tumor cells
Front Immunol, 14, 1178817
DOI 10.3389/fimmu.2023.1178817, PubMed 37346044
Gene Regulatory Interactions at Lamina-Associated Domains
Genes (Basel), 14 (2)
DOI 10.3390/genes14020334, PubMed 36833261
Assessing IgE sensitization profiles to birch and timothy grass pollen allergens in birch pollen allergic blood donors using an oligoplex specific IgE assay
Scand J Clin Lab Invest, 83 (7), 444-447
DOI 10.1080/00365513.2023.2255972, PubMed 37737679
Iatrogenic air embolism: pathoanatomy, thromboinflammation, endotheliopathy, and therapies
Front Immunol, 14, 1230049
DOI 10.3389/fimmu.2023.1230049, PubMed 37795086
Preclinical Evaluation of a 64Cu-Based Theranostic Approach in a Murine Model of Multiple Myeloma
Pharmaceutics, 15 (7)
DOI 10.3390/pharmaceutics15071817, PubMed 37514004
Prevalent and immunodominant CD8 T cell epitopes are conserved in SARS-CoV-2 variants
Cell Rep, 42 (1), 111995
DOI 10.1016/j.celrep.2023.111995, PubMed 36656713
Effects of storage on quality and function of acid-treated platelets with reduced HLA Class I surface expression
Transfus Med, 33 (4), 329-336
DOI 10.1111/tme.12983, PubMed 37356816
A homozygous POLR1A variant causes leukodystrophy and affects protein homeostasis
Brain, 146 (8), 3513-3527
DOI 10.1093/brain/awad086, PubMed 36917474
Cytosolic antibody receptor TRIM21 is required for effective tau immunotherapy in mouse models
Science, 379 (6639), 1336-1341
DOI 10.1126/science.abn1366, PubMed 36996217
Circulating markers of extracellular matrix remodelling in severe COVID-19 patients
J Intern Med, 294 (6), 784-797
DOI 10.1111/joim.13725, PubMed 37718572
H2S-Enriched Flush out Does Not Increase Donor Organ Quality in a Porcine Kidney Perfusion Model
Antioxidants (Basel), 12 (3)
DOI 10.3390/antiox12030749, PubMed 36978997
Quartz Crystal Microbalance Platform for SARS-CoV-2 Immuno-Diagnostics
Int J Mol Sci, 24 (23)
DOI 10.3390/ijms242316705, PubMed 38069027
Convalescent plasma from Norwegian blood donors to treat COVID-19
Tidsskr Nor Laegeforen, 143 (11)
DOI 10.4045/tidsskr.22.0180, PubMed 37589362
Characterizations of a neutralizing antibody broadly reactive to multiple gluten peptide:HLA-DQ2.5 complexes in the context of celiac disease
Nat Commun, 14 (1), 8502
DOI 10.1038/s41467-023-44083-4, PubMed 38135691
Simultaneous LC-MS determination of glucose regulatory peptides secreted by stem cell-derived islet organoids
Electrophoresis, 44 (21-22), 1682-1697
DOI 10.1002/elps.202300095, PubMed 37574258
Single-cell transcriptomics combined with proteomics of intrathecal IgG reveal transcriptional heterogeneity of oligoclonal IgG-secreting cells in multiple sclerosis
Front Cell Neurosci, 17, 1189709
DOI 10.3389/fncel.2023.1189709, PubMed 37362001
Defining and Studying B Cell Receptor and TCR Interactions
J Immunol, 211 (3), 311-322
DOI 10.4049/jimmunol.2300136, PubMed 37459189
Determinants of humoral and cellular immune responses to three doses of mRNA SARS-CoV-2 vaccines in older adults: a longitudinal cohort study
Lancet Healthy Longev, 4 (5), e188-e199
DOI 10.1016/S2666-7568(23)00055-7, PubMed 37148891
Safety of hypoxic red blood cell administration in patients with transfusion-dependent hematological malignancies: An interim analysis
Transfus Apher Sci, 62 (5), 103755
DOI 10.1016/j.transci.2023.103755, PubMed 37423867
Active maintenance of CD8+ T cell naivety through regulation of global genome architecture
Cell Rep, 42 (10), 113301
DOI 10.1016/j.celrep.2023.113301, PubMed 37858463
Local Postoperative Graft Inflammation in Pancreas Transplant Patients With Early Graft Thrombosis
Transplant Direct, 10 (1), e1567
DOI 10.1097/TXD.0000000000001567, PubMed 38094132
Thromboinflammatory response is increased in pancreas transplant alone versus simultaneous pancreas-kidney transplantation and early pancreas graft thrombosis is associated with complement activation
Front Immunol, 14, 1044444
DOI 10.3389/fimmu.2023.1044444, PubMed 37063904
Small extracellular vesicles have distinct CD81 and CD9 tetraspanin expression profiles in plasma from rheumatoid arthritis patients
Clin Exp Med, 23 (6), 2867-2875
DOI 10.1007/s10238-023-01024-1, PubMed 36826611
Identifying a core protein signature of small extracellular vesicles derived from B-cell precursor acute lymphoblastic leukaemia
Scand J Immunol, 99 (3), e13341
DOI 10.1111/sji.13341, PubMed 38441169
Plasma Inflammatory Biomarkers Are Associated With Poststroke Cognitive Impairment: The Nor-COAST Study
Stroke, 54 (5), 1303-1311
DOI 10.1161/STROKEAHA.122.041965, PubMed 37026459
Prevalence and Characteristics Associated With Post-COVID-19 Condition Among Nonhospitalized Adolescents and Young Adults
JAMA Netw Open, 6 (3), e235763
DOI 10.1001/jamanetworkopen.2023.5763, PubMed 36995712
Predicting the immune escape of SARS-CoV-2 neutralizing antibodies upon mutation
Biochim Biophys Acta Mol Basis Dis, 1870 (2), 166959
DOI 10.1016/j.bbadis.2023.166959, PubMed 37967796
A role for the terminal C5-C9 complement pathway in idiopathic pulmonary fibrosis
Front Med (Lausanne), 10, 1236495
DOI 10.3389/fmed.2023.1236495, PubMed 37621463
Complement factors B, D, C3bBbP and risk of future venous thromboembolism
Clin Immunol, 249, 109278
DOI 10.1016/j.clim.2023.109278, PubMed 36894046
Transdiagnostic Associations between Anger Hostility and Chemokine Interferon-gamma Inducible Protein 10
Clin Psychopharmacol Neurosci, 22 (2), 285-294
DOI 10.9758/cpn.23.1091, PubMed 38627075
Inflammatory markers and pulmonary function in adolescents and young adults 6 months after mild COVID-19
Front Immunol, 13, 1081718
DOI 10.3389/fimmu.2022.1081718, PubMed 36685555
Terminating Routine Cord Blood RhD Typing of the Newborns to Guide Postnatal Anti-D Immunoglobulin Prophylaxis Based on the Results of Fetal RHD Genotyping
Fetal Diagn Ther, 50 (4), 276-281
DOI 10.1159/000531694, PubMed 37379821
Effect of Intraperitoneal 224Radium-Labelled Microparticles on Compartmentalized Inflammation After Cytoreductive Surgery and Hypertherm Intraperitoneal Chemotherapy
Technol Cancer Res Treat, 22, 15330338231192902
DOI 10.1177/15330338231192902, PubMed 37574949
Design and preclinical testing of an anti-CD41 CAR T cell for the treatment of acute megakaryoblastic leukaemia
J Cell Mol Med, 27 (19), 2864-2875
DOI 10.1111/jcmm.17810, PubMed 37667538
RNA sequencing suggests that non-coding RNAs play a role in the development of acquired haemophilia
J Cell Mol Med, 27 (13), 1790-1796
DOI 10.1111/jcmm.17741, PubMed 37317065
Pathology and Molecular Biology of Melanoma
Curr Issues Mol Biol, 45 (7), 5575-5597
DOI 10.3390/cimb45070352, PubMed 37504268
Trimeric, APC-Targeted Subunit Vaccines Protect Mice against Seasonal and Pandemic Influenza
J Virol, 97 (2), e0169422
DOI 10.1128/jvi.01694-22, PubMed 36719241
Efficacy and safety of baricitinib in hospitalized adults with severe or critical COVID-19 (Bari-SolidAct): a randomised, double-blind, placebo-controlled phase 3 trial
Crit Care, 27 (1), 9
DOI 10.1186/s13054-022-04205-8, PubMed 36627655
A Mouse Model for the Rapid and Binomial Assessment of Putative WNT/β-Catenin Signalling Inhibitors
Biomedicines, 11 (10)
DOI 10.3390/biomedicines11102719, PubMed 37893093
Phage display assisted discovery of a pH-dependent anti-α-cobratoxin antibody from a natural variable domain library
Protein Sci, 32 (12), e4821
DOI 10.1002/pro.4821, PubMed 37897425
Coagulopathy and adverse outcomes in hospitalized patients with COVID-19: results from the NOR-Solidarity trial
Res Pract Thromb Haemost, 8 (1), 102289
DOI 10.1016/j.rpth.2023.102289, PubMed 38292350
Increased muscle activity during sleep and more RBD symptoms in H1N1-(Pandemrix)-vaccinated narcolepsy type 1 patients compared with their non-narcoleptic siblings
Sleep, 46 (3)
DOI 10.1093/sleep/zsac316, PubMed 36562330
Pediatric glioma histone H3.3 K27M/G34R mutations drive abnormalities in PML nuclear bodies
Genome Biol, 24 (1), 284
DOI 10.1186/s13059-023-03122-5, PubMed 38066546
Liquid Biopsy in Organ Damage: small extracellular vesicle chip-based assessment of polytrauma
Front Immunol, 14, 1279496
DOI 10.3389/fimmu.2023.1279496, PubMed 38035093
Neuraminidase delivered as an APC-targeted DNA vaccine induces protective antibodies against influenza
Mol Ther, 31 (7), 2188-2205
DOI 10.1016/j.ymthe.2023.03.012, PubMed 36926694
Id-neoantigen vaccine induces therapeutic CD8+ T cells against multiple myeloma: H chain-loss escapees cause FLC MM
J Immunother Cancer, 11 (8)
DOI 10.1136/jitc-2023-006944, PubMed 37607769
Characterization of human stem cell-derived hepatic stellate cells and liver sinusoidal endothelial cells during extended in vitro culture
Front Bioeng Biotechnol, 11, 1223737
DOI 10.3389/fbioe.2023.1223737, PubMed 37560536
T cell responses to SARS-CoV-2 vaccination differ by disease-modifying therapy for multiple sclerosis
JCI Insight, 8 (12)
DOI 10.1172/jci.insight.165111, PubMed 37159281
Distinct microRNA and protein profiles of extracellular vesicles secreted from myotubes from morbidly obese donors with type 2 diabetes in response to electrical pulse stimulation
Front Physiol, 14, 1143966
DOI 10.3389/fphys.2023.1143966, PubMed 37064893