Publika - Scientific publications from Oslo University Hospital

RSS feed RSS

Publications (original articles or review articles) published in 2021 from OUS - Department of Pathology

120 publications found

Andersson Y, Fleten KG, Abrahamsen TW, Reed W, Davidson B, Flatmark K (2021)
Anti-Angiogenic Treatment in Pseudomyxoma Peritonei-Still a Strong Preclinical Rationale
Cancers (Basel), 13 (11)
DOI 10.3390/cancers13112819, PubMed 34198773

Autio M, Leivonen SK, Brück O, Mustjoki S, Mészáros Jørgensen J, Karjalainen-Lindsberg ML, Beiske K, Holte H, Pellinen T, Leppä S (2021)
Immune cell constitution in the tumor microenvironment predicts the outcome in diffuse large B-cell lymphoma
Haematologica, 106 (3), 718-729
DOI 10.3324/haematol.2019.243626, PubMed 32079690

Balta MG, Papathanasiou E, Christopoulos PF (2021)
Specialized Pro-Resolving Mediators as Potential Regulators of Inflammatory Macrophage Responses in COVID-19
Front Immunol, 12, 632238
DOI 10.3389/fimmu.2021.632238, PubMed 33717168

Bascuñana P, Brackhan M, Pahnke J (2021)
Machine Learning-Supported Analyses Improve Quantitative Histological Assessments of Amyloid-β Deposits and Activated Microglia
J Alzheimers Dis, 79 (2), 597-605
DOI 10.3233/JAD-201120, PubMed 33337377

Bascuñana P, Wolf BJ, Jahreis I, Brackhan M, García-García L, Ross TL, Bengel FM, Bankstahl M, Bankstahl JP (2021)
99mTc-HMPAO SPECT imaging reveals brain hypoperfusion during status epilepticus
Metab Brain Dis, 36 (8), 2597-2602
DOI 10.1007/s11011-021-00843-z, PubMed 34570340

Bellini A, Pötschger U, Bernard V, Lapouble E, Baulande S, Ambros PF, Auger N, Beiske K, Bernkopf M, Betts DR, Bhalshankar J, Bown N, de Preter K, Clément N, Combaret V, Font de Mora J, George SL, Jiménez I, Jeison M, Marques B, Martinsson T, Mazzocco K, Morini M, Mühlethaler-Mottet A, Noguera R et al. (2021)
Frequency and Prognostic Impact of ALK Amplifications and Mutations in the European Neuroblastoma Study Group (SIOPEN) High-Risk Neuroblastoma Trial (HR-NBL1)
J Clin Oncol, 39 (30), 3377-3390
DOI 10.1200/JCO.21.00086, PubMed 34115544

Berland S, Rustad CF, Bentsen MHL, Wollen EJ, Turowski G, Johansson S, Houge G, Haukanes BI (2021)
Double paternal uniparental isodisomy 7 and 15 presenting with Beckwith-Wiedemann spectrum features
Cold Spring Harb Mol Case Stud, 7 (6)
DOI 10.1101/mcs.a006113, PubMed 34615670

Bjaanæs MM, Nilsen G, Halvorsen AR, Russnes HG, Solberg S, Jørgensen L, Brustugun OT, Lingjærde OC, Helland Å (2021)
Whole genome copy number analyses reveal a highly aberrant genome in TP53 mutant lung adenocarcinoma tumors
BMC Cancer, 21 (1), 1089
DOI 10.1186/s12885-021-08811-7, PubMed 34625038

Blümcke I, Coras R, Busch RM, Morita-Sherman M, Lal D, Prayson R, Cendes F, Lopes-Cendes I, Rogerio F, Almeida VS, Rocha CS, Sim NS, Lee JH, Kim SH, Baulac S, Baldassari S, Adle-Biassette H, Walsh CA, Bizzotto S, Doan RN, Morillo KS, Aronica E, Mühlebner A, Becker A, Cienfuegos J et al. (2021)
Toward a better definition of focal cortical dysplasia: An iterative histopathological and genetic agreement trial
Epilepsia, 62 (6), 1416-1428
DOI 10.1111/epi.16899, PubMed 33949696

Boye K, Longhi A, Guren T, Lorenz S, Næss S, Pierini M, Taksdal I, Lobmaier I, Cesari M, Paioli A, Løndalen AM, Setola E, Hompland I, Meza-Zepeda LA, Sundby Hall K, Palmerini E (2021)
Pembrolizumab in advanced osteosarcoma: results of a single-arm, open-label, phase 2 trial
Cancer Immunol Immunother, 70 (9), 2617-2624
DOI 10.1007/s00262-021-02876-w, PubMed 33580363

Bruun J, Eide PW, Bergsland CH, Bruck O, Svindland A, Arjama M, Välimäki K, Bjørnslett M, Guren MG, Kallioniemi O, Nesbakken A, Lothe RA, Pellinen T (2021)
E-cadherin is a robust prognostic biomarker in colorectal cancer and low expression is associated with sensitivity to inhibitors of topoisomerase, aurora, and HSP90 in preclinical models
Mol Oncol, 16 (12), 2312-2329
DOI 10.1002/1878-0261.13159, PubMed 34890102

Casar-Borota O, Boldt HB, Engström BE, Andersen MS, Baussart B, Bengtsson D, Berinder K, Ekman B, Feldt-Rasmussen U, Höybye C, Jørgensen JOL, Kolnes AJ, Korbonits M, Rasmussen ÅK, Lindsay JR, Loughrey PB, Maiter D, Manojlovic-Gacic E, Pahnke J, Poliani PL, Popovic V, Ragnarsson O, Schalin-Jäntti C, Scheie D, Tóth M et al. (2021)
Corticotroph Aggressive Pituitary Tumors and Carcinomas Frequently Harbor ATRX Mutations
J Clin Endocrinol Metab, 106 (4), 1183-1194
DOI 10.1210/clinem/dgaa749, PubMed 33106857

Cederkvist H, Kolan SS, Wik JA, Sener Z, Skålhegg BS (2021)
Identification and characterization of a novel glutaminase inhibitor
FEBS Open Bio, 12 (1), 163-174
DOI 10.1002/2211-5463.13319, PubMed 34698439

Chen Y, Klingen TA, Aas H, Wik E, Akslen LA (2021)
Tumor-associated lymphocytes and macrophages are related to stromal elastosis and vascular invasion in breast cancer
J Pathol Clin Res, 7 (5), 517-527
DOI 10.1002/cjp2.226, PubMed 34076969

Christensen E, Foss OA, Quist-Paulsen P, Staur I, Pettersen F, Holien T, Juzenas P, Peng Q (2021)
Application of Photodynamic Therapy with 5-Aminolevulinic Acid to Extracorporeal Photopheresis in the Treatment of Patients with Chronic Graft-versus-Host Disease: A First-in-Human Study
Pharmaceutics, 13 (10)
DOI 10.3390/pharmaceutics13101558, PubMed 34683851

Christopoulos PF (2021)
The future of tumor vaccines in the post-COVID-19 era-Current challenges
Immun Inflamm Dis, 9 (4), 1795-1797
DOI 10.1002/iid3.521, PubMed 34473900

Christopoulos PF, Gjølberg TT, Krüger S, Haraldsen G, Andersen JT, Sundlisæter E (2021)
Targeting the Notch Signaling Pathway in Chronic Inflammatory Diseases
Front Immunol, 12, 668207
DOI 10.3389/fimmu.2021.668207, PubMed 33912195

Christopoulos PF, Grigalavicius M, Corthay A, Berg K, Theodossiou TA (2021)
Reactive Species from Two-Signal Activated Macrophages Interfere with Their Oxygen Consumption Measurements
Antioxidants (Basel), 10 (7)
DOI 10.3390/antiox10071149, PubMed 34356382

Corthay A, Bakacs T, Thangavelu G, Anderson CC (2021)
Tackling cancer cell dormancy: Insights from immune models, and transplantation
Semin Cancer Biol, 78, 5-16
DOI 10.1016/j.semcancer.2021.02.002, PubMed 33582171

Dagenborg VJ, Marshall SE, Grzyb K, Fretland ÅA, Lund-Iversen M, Mælandsmo GM, Ree AH, Edwin B, Yaqub S, Flatmark K (2021)
Low Concordance Between T-Cell Densities in Matched Primary Tumors and Liver Metastases in Microsatellite Stable Colorectal Cancer
Front Oncol, 11, 671629
DOI 10.3389/fonc.2021.671629, PubMed 34178659

Dalmasso B, Pastorino L, Nathan V, Shah NN, Palmer JM, Howlie M, Johansson PA, Freedman ND, Carter BD, Beane-Freeman L, Hicks B, Molven A, Helgadottir H, Sankar A, Tsao H, Stratigos AJ, Helsing P, Van Doorn R, Gruis NA, Visser M, Wadt KAW, Mann G, Holland EA, Nagore E, Potrony M et al. (2021)
Germline ATM variants predispose to melanoma: a joint analysis across the GenoMEL and MelaNostrum consortia
Genet Med, 23 (11), 2087-2095
DOI 10.1038/s41436-021-01240-8, PubMed 34262154

Davidson B, Kleinberg L, Børresen IM, Slettevoll F, Fangberget A, Hindosh D, Zahl Eriksson AG, Bjerkehagen B (2021)
Primary uterine ectomesenchymoma harboring a DICER1 mutation: case report with molecular analysis
Virchows Arch, 479 (2), 419-424
DOI 10.1007/s00428-021-03057-x, PubMed 33595736

DE Angelis PM, Dorg L, Pham S, Andersen SN (2021)
DNA Repair Protein Expression and Oxidative/Nitrosative Stress in Ulcerative Colitis and Sporadic Colorectal Cancer
Anticancer Res, 41 (7), 3261-3270
DOI 10.21873/anticanres.15112, PubMed 34230120

Dib S, Pahnke J, Gosselet F (2021)
Role of ABCA7 in Human Health and in Alzheimer's Disease
Int J Mol Sci, 22 (9)
DOI 10.3390/ijms22094603, PubMed 33925691

Djirackor L, Halldorsson S, Niehusmann P, Leske H, Capper D, Kuschel LP, Pahnke J, Due-Tønnessen BJ, Langmoen IA, Sandberg CJ, Euskirchen P, Vik-Mo EO (2021)
Intraoperative DNA methylation classification of brain tumors impacts neurosurgical strategy
Neurooncol Adv, 3 (1), vdab149
DOI 10.1093/noajnl/vdab149, PubMed 34729487

Engebraaten O, Yau C, Berg K, Borgen E, Garred Ø, Berstad MEB, Fremstedal ASV, DeMichele A, Veer LV', Esserman L, Weyergang A (2021)
RAB5A expression is a predictive biomarker for trastuzumab emtansine in breast cancer
Nat Commun, 12 (1), 6427
DOI 10.1038/s41467-021-26018-z, PubMed 34741021

Eriksson AGZ, Davidson B, Bjerre Trent P, Eyjólfsdóttir B, Dahl GF, Wang Y, Staff AC (2021)
Update on Sentinel Lymph Node Biopsy in Surgical Staging of Endometrial Carcinoma
J Clin Med, 10 (14)
DOI 10.3390/jcm10143094, PubMed 34300260

Eriksson AM, Leikfoss IS, Abrahamsen G, Sundvold V, Isom MM, Keshari PK, Rognes T, Landsverk OJB, Bos SD, Harbo HF, Spurkland A, Berge T (2021)
Exploring the role of the multiple sclerosis susceptibility gene CLEC16A in T cells
Scand J Immunol, 94 (1), e13050
DOI 10.1111/sji.13050, PubMed 34643957

Fjær R, Marciniak K, Sundnes O, Hjorthaug H, Sheng Y, Hammarström C, Sitek JC, Vigeland MD, Backe PH, Øye AM, Fosse JH, Stav-Noraas TE, Uchiyama Y, Matsumoto N, Comi A, Pevsner J, Haraldsen G, Selmer KK (2021)
A novel somatic mutation in GNB2 provides new insights to the pathogenesis of Sturge-Weber syndrome
Hum Mol Genet, 30 (21), 1919-1931
DOI 10.1093/hmg/ddab144, PubMed 34124757

Flatmark K, Torgunrud A, Fleten KG, Davidson B, Juul HV, Mensali N, Lund-Andersen C, Inderberg EM (2021)
Peptide vaccine targeting mutated GNAS: a potential novel treatment for pseudomyxoma peritonei
J Immunother Cancer, 9 (10)
DOI 10.1136/jitc-2021-003109, PubMed 34711663

Fosheim IK, Johnsen GM, Alnaes-Katjavivi P, Turowski G, Sugulle M, Staff AC (2021)
Decidua basalis and acute atherosis: Expression of atherosclerotic foam cell associated proteins
Placenta, 107, 1-7
DOI 10.1016/j.placenta.2021.03.001, PubMed 33725567

Fosse JH, Haraldsen G, Falk K, Edelmann R (2021)
Endothelial Cells in Emerging Viral Infections
Front Cardiovasc Med, 8, 619690
DOI 10.3389/fcvm.2021.619690, PubMed 33718448

Frafjord A, Buer L, Hammarström C, Aamodt H, Woldbæk PR, Brustugun OT, Helland Å, Øynebråten I, Corthay A (2021)
The Immune Landscape of Human Primary Lung Tumors Is Th2 Skewed
Front Immunol, 12, 764596
DOI 10.3389/fimmu.2021.764596, PubMed 34868011

Frerker N, Karlsen TA, Lilledahl MB, Brorson SH, Tibballs JE, Brinchmann JE (2021)
Scaffold-Free Engineering of Human Cartilage Implants
Cartilage, 13 (1_suppl), 1237S-1249S
DOI 10.1177/19476035211007923, PubMed 33858229

Følling I, Wennerstrøm AB, Eide TJ, Nilsen HL (2021)
Phaeochromocytomas overexpress insulin transcript and produce insulin
Endocr Connect, 10 (8), 815-824
DOI 10.1530/EC-21-0269, PubMed 34170845

García de Jalón E, Kleinmanns K, Fosse V, Davidson B, Bjørge L, Haug BE, McCormack E (2021)
Comparison of Five Near-Infrared Fluorescent Folate Conjugates in an Ovarian Cancer Model
Mol Imaging Biol, 25 (1), 144-155
DOI 10.1007/s11307-021-01685-y, PubMed 34888759

Gatti F, Mia S, Hammarström C, Frerker N, Fosby B, Wang J, Pietka W, Sundnes O, Hol J, Kasprzycka M, Haraldsen G (2021)
Nuclear IL-33 restrains the early conversion of fibroblasts to an extracellular matrix-secreting phenotype
Sci Rep, 11 (1), 108
DOI 10.1038/s41598-020-80509-5, PubMed 33420328

Georgiesh T, Namløs HM, Sharma N, Lorenz S, Myklebost O, Bjerkehagen B, Meza-Zepeda LA, Boye K (2021)
Clinical and molecular implications of NAB2-STAT6 fusion variants in solitary fibrous tumour
Pathology, 53 (6), 713-719
DOI 10.1016/j.pathol.2020.11.010, PubMed 33745702

Golburean O, Hagen MH, Uncuta D, Tighineanu M, Manrikyan G, Vardanian I, Andresen C, Singh B, Porosencova T, Ivasiuc I, Cheptanaru O, Markaryan M, Shakavets N, Sapkota D, Søland TM, Costea DE, Özkaya F (2021)
Knowledge, opinions, and practices related to oral cancer prevention and oral mucosal examination among dentists in Moldova, Belarus and Armenia: a multi-country cross-sectional study
BMC Oral Health, 21 (1), 652
DOI 10.1186/s12903-021-02011-2, PubMed 34922498

Hartkopf AD, Brucker SY, Taran FA, Harbeck N, von Au A, Naume B, Pierga JY, Hoffmann O, Beckmann MW, Rydén L, Fehm T, Aft R, Solà M, Walter V, Rack B, Schuetz F, Borgen E, Ta MH, Bittner AK, Fasching PA, Fernö M, Krawczyk N, Weilbaecher K, Margelí M, Hahn M et al. (2021)
Disseminated tumour cells from the bone marrow of early breast cancer patients: Results from an international pooled analysis
Eur J Cancer, 154, 128-137
DOI 10.1016/j.ejca.2021.06.028, PubMed 34265505

Haugen MH, Lingjærde OC, Hedenfalk I, Garred Ø, Borgen E, Loman N, Hatschek T, Børresen-Dale AL, Naume B, Mills GB, Mælandsmo GM, Engebraaten O (2021)
Protein Signature Predicts Response to Neoadjuvant Treatment With Chemotherapy and Bevacizumab in HER2-Negative Breast Cancers
JCO Precis Oncol, 5
DOI 10.1200/PO.20.00086, PubMed 34036235

Hemsing AL, Gjertsen BT, Spetalen S, Helgeland L, Reikvam H (2021)
Favorable outcome of a patient with an unclassifiable myelodysplastic syndrome/myeloproliferative neoplasm treated with allogeneic hematopoietic stem cell transplantation
SAGE Open Med Case Rep, 9, 2050313X20988413
DOI 10.1177/2050313X20988413, PubMed 33628448

Hermansen JU, Wojcik DM, Robinson N, Pahnke J, Haugland HK, Jamtøy AH, Flaegstad T, Halvorsen H, Lund B, Baumbusch LO, Munthe-Kaas MC (2021)
The Norwegian childhood cancer biobank
Cancer Rep (Hoboken), 5 (8), e1555
DOI 10.1002/cnr2.1555, PubMed 34541832

Hole KH, Tulipan AJ, Reijnen JS, Hernes E, Vlatkovic L, Lie AK, Revheim ME, Seierstad T (2021)
Localization of primary prostate cancer: FACBC PET/CT compared with multiparametric MRI using histopathology as reference standard
Am J Nucl Med Mol Imaging, 11 (5), 387-394
PubMed 34754609

Hompland I, Ferrari S, Bielack S, Palmerini E, Hall KS, Picci P, Hecker-Nolting S, Donati DM, Blattmann C, Bjerkehagen B, Staals E, Kager L, Gambarotti M, Kühne T, Eriksson M, Ferraresi V, Kevric M, Biagini R, Baumhoer D, Brosjø O, Comandone A, Schwarz R, Bertulli R, Kessler T, Hansson L et al. (2021)
Outcome in dedifferentiated chondrosarcoma for patients treated with multimodal therapy: Results from the EUROpean Bone Over 40 Sarcoma Study
Eur J Cancer, 151, 150-158
DOI 10.1016/j.ejca.2021.04.017, PubMed 33990016

Hopland OA, Fosså SD, Ottosson F, Brennhovd B, Svindland A, Hole KH, Hernes E, Eri LM, Diep LM, Berge V (2021)
Robotic salvage pelvic lymph node dissection for locoregional recurrence after radical prostatectomy: a single institution experience
Scand J Urol, 55 (4), 287-292
DOI 10.1080/21681805.2021.1946135, PubMed 34196594

Hugenschmidt H, Labori KJ, Borgen E, Brunborg C, Schirmer CB, Seeberg LT, Naume B, Wiedswang G (2021)
Preoperative CTC-Detection by CellSearch® Is Associated with Early Distant Metastasis and Impaired Survival in Resected Pancreatic Cancer
Cancers (Basel), 13 (3)
DOI 10.3390/cancers13030485, PubMed 33513877

Hølmebakk T, Wiedswang AM, Meza-Zepeda LA, Hompland I, Lobmaier IVK, Berner JM, Stoldt S, Boye K (2021)
Integrating Anatomical, Molecular and Clinical Risk Factors in Gastrointestinal Stromal Tumor of the Stomach
Ann Surg Oncol, 28 (11), 6837-6845
DOI 10.1245/s10434-021-09605-8, PubMed 33651216

Høydahl LS, Frigstad T, Rasmussen IB, Øynebråten I, Schjetne KW, Andersen JT, Michaelsen TE, Lunde E, Bogen B, Sandlie I (2021)
Antibody-mediated delivery of T-cell epitopes to antigen-presenting cells induce strong CD4 and CD8 T-cell responses
Vaccine, 39 (11), 1583-1592
DOI 10.1016/j.vaccine.2021.02.012, PubMed 33612340

Islam R, Islam MM, Nilsson PH, Mohlin C, Hagen KT, Paschalis EI, Woods RL, Bhowmick SC, Dohlman CH, Espevik T, Chodosh J, Gonzalez-Andrades M, Mollnes TE (2021)
Combined blockade of complement C5 and TLR co-receptor CD14 synergistically inhibits pig-to-human corneal xenograft induced innate inflammatory responses
Acta Biomater, 127, 169-179
DOI 10.1016/j.actbio.2021.03.047, PubMed 33785451

Jacobs Catane L, Moshel O, Smith Y, Davidson B, Reich R (2021)
Splice-Variant Knock-Out of TGFβ Receptors Perturbates the Proteome of Ovarian Carcinoma Cells
Int J Mol Sci, 22 (23)
DOI 10.3390/ijms222312647, PubMed 34884451

Janiszewska M, Stein S, Metzger Filho O, Eng J, Kingston NL, Harper NW, Rye IH, Alečković M, Trinh A, Murphy KC, Marangoni E, Cristea S, Oakes B, Winer EP, Krop IE, Russnes HG, Spellman PT, Bucher E, Hu Z, Chin K, Gray JW, Michor F, Polyak K (2021)
The impact of tumor epithelial and microenvironmental heterogeneity on treatment responses in HER2+ breast cancer
JCI Insight, 6 (11)
DOI 10.1172/jci.insight.147617, PubMed 33886505

Jaroy EG, Emblem R, Reims HM, Mai TT, Risa GT, Ougland R (2021)
Evaluation of diagnostic factors used to refer children with constipation for rectal biopsies
Int J Colorectal Dis, 37 (3), 597-605
DOI 10.1007/s00384-021-04069-4, PubMed 34882271

Jodal HC, Klotz D, Herfindal M, Barua I, Tag P, Helsingen LM, Refsum E, Holme Ø, Adami HO, Bretthauer M, Kalager M, Løberg M (2021)
Long-term colorectal cancer incidence and mortality after adenoma removal in women and men
Aliment Pharmacol Ther, 55 (4), 412-421
DOI 10.1111/apt.16686, PubMed 34716941

Johansson ALV, Trewin CB, Fredriksson I, Reinertsen KV, Russnes H, Ursin G (2021)
In modern times, how important are breast cancer stage, grade and receptor subtype for survival: a population-based cohort study
Breast Cancer Res, 23 (1), 17
DOI 10.1186/s13058-021-01393-z, PubMed 33526044

Juraleviciute M, Nsengimana J, Newton-Bishop J, Hendriks GJ, Slipicevic A (2021)
MX2 mediates establishment of interferon response profile, regulates XAF1, and can sensitize melanoma cells to targeted therapy
Cancer Med, 10 (8), 2840-2854
DOI 10.1002/cam4.3846, PubMed 33734579

Jørgensen SF, Buechner J, Myhre AE, Galteland E, Spetalen S, Kulseth MA, Sorte HS, Holla ØL, Lundman E, Alme C, Heier I, Flægstad T, Fløisand Y, Benneche A, Fevang B, Aukrust P, Stray-Pedersen A, Gedde-Dahl T, Nordøy I (2021)
A Nationwide Study of GATA2 Deficiency in Norway-the Majority of Patients Have Undergone Allo-HSCT
J Clin Immunol, 42 (2), 404-420
DOI 10.1007/s10875-021-01189-y, PubMed 34893945

Kalogirou EM, Tosios KI, Christopoulos PF (2021)
The Role of Macrophages in Oral Squamous Cell Carcinoma
Front Oncol, 11, 611115
DOI 10.3389/fonc.2021.611115, PubMed 33816242

Kidd SG, Carm KT, Bogaard M, Olsen LG, Bakken AC, Løvf M, Lothe RA, Axcrona K, Axcrona U, Skotheim RI (2021)
High expression of SCHLAP1 in primary prostate cancer is an independent predictor of biochemical recurrence, despite substantial heterogeneity
Neoplasia, 23 (6), 634-641
DOI 10.1016/j.neo.2021.05.012, PubMed 34107378

Klingen TA, Chen Y, Aas H, Wik E, Akslen LA (2021)
Fibulin-2 expression associates with vascular invasion and patient survival in breast cancer
PLoS One, 16 (4), e0249767
DOI 10.1371/journal.pone.0249767, PubMed 33836007

Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM et al. (2021)
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
Autophagy, 17 (1), 1-382
DOI 10.1080/15548627.2020.1797280, PubMed 33634751

Kromp F, Fischer L, Bozsaky E, Ambros IM, Dorr W, Beiske K, Ambros PF, Hanbury A, Taschner-Mandl S (2021)
Evaluation of Deep Learning Architectures for Complex Immunofluorescence Nuclear Image Segmentation
IEEE Trans Med Imaging, 40 (7), 1934-1949
DOI 10.1109/TMI.2021.3069558, PubMed 33784615

Krüger K, Silwal-Pandit L, Wik E, Straume O, Stefansson IM, Borgen E, Garred Ø, Naume B, Engebraaten O, Akslen LA (2021)
Baseline microvessel density predicts response to neoadjuvant bevacizumab treatment of locally advanced breast cancer
Sci Rep, 11 (1), 3388
DOI 10.1038/s41598-021-81914-0, PubMed 33564016

Leske H, Dalgleish R, Lazar AJ, Reifenberger G, Cree IA (2021)
A common classification framework for histone sequence alterations in tumours: an expert consensus proposal
J Pathol, 254 (2), 109-120
DOI 10.1002/path.5666, PubMed 33779999

Li G, Kolan SS, Guo S, Marciniak K, Kolan P, Malachin G, Grimolizzi F, Haraldsen G, Skålhegg BS (2021)
Activated, Pro-Inflammatory Th1, Th17, and Memory CD4+ T Cells and B Cells Are Involved in Delayed-Type Hypersensitivity Arthritis (DTHA) Inflammation and Paw Swelling in Mice
Front Immunol, 12, 689057
DOI 10.3389/fimmu.2021.689057, PubMed 34408746

Li J, Fang K, Choppavarapu L, Yang K, Yang Y, Wang J, Cao R, Jatoi I, Jin VX (2021)
Hi-C profiling of cancer spheroids identifies 3D-growth-specific chromatin interactions in breast cancer endocrine resistance
Clin Epigenetics, 13 (1), 175
DOI 10.1186/s13148-021-01167-6, PubMed 34535185

Lien TG, Ohnstad HO, Lingjærde OC, Vallon-Christersson J, Aaserud M, Sveli MAT, Borg Å, Osbreac OBO, Garred Ø, Borgen E, Naume B, Russnes H, Sørlie T (2021)
Sample Preparation Approach Influences PAM50 Risk of Recurrence Score in Early Breast Cancer
Cancers (Basel), 13 (23)
DOI 10.3390/cancers13236118, PubMed 34885228

Lorvik KB, Meyer-Myklestad MH, Kushekar K, Handeland C, Medhus AW, Lund-Iversen M, Stiksrud B, Kvale D, Dyrhol-Riise AM, Taskén K, Reikvam DH (2021)
Enhanced Gut-Homing Dynamics and Pronounced Exhaustion of Mucosal and Blood CD4+ T Cells in HIV-Infected Immunological Non-Responders
Front Immunol, 12, 744155
DOI 10.3389/fimmu.2021.744155, PubMed 34691047

Lossius AH, Sundnes O, Ingham AC, Edslev SM, Bjørnholt JV, Lilje B, Bradley M, Asad S, Haraldsen G, Skytt-Andersen P, Holm JØ, Berents TL (2021)
Shifts in the Skin Microbiota after UVB Treatment in Adult Atopic Dermatitis
Dermatology, 238 (1), 109-120
DOI 10.1159/000515236, PubMed 33887725

Mitlid-Mork B, Turowski G, Bowe S, Staff AC, Sugulle M (2021)
Circulating angiogenic profiles and histo-morphological placental characteristics of uncomplicated post-date pregnancies
Placenta, 109, 55-63
DOI 10.1016/j.placenta.2021.04.017, PubMed 33990027

Munthe-Kaas MC, Forthun RB, Brendehaug A, Eek AK, Høysæter T, Osnes LTN, Prescott T, Spetalen S, Hovland R (2021)
Partial Response to Sorafenib in a Child With a Myeloid/Lymphoid Neoplasm, Eosinophilia, and a ZMYM2-FLT3 Fusion
J Pediatr Hematol Oncol, 43 (4), e508-e511
DOI 10.1097/MPH.0000000000001890, PubMed 32852395

Möhle L, Bascuñana P, Brackhan M, Pahnke J (2021)
Development of deep learning models for microglia analyses in brain tissue using DeePathology™ STUDIO
J Neurosci Methods, 364, 109371
DOI 10.1016/j.jneumeth.2021.109371, PubMed 34592173

Möhle L, Brackhan M, Bascuñana P, Pahnke J (2021)
Dimethyl fumarate does not mitigate cognitive decline and β-amyloidosis in female APPPS1 mice
Brain Res, 1768, 147579
DOI 10.1016/j.brainres.2021.147579, PubMed 34233173

Namasivayam V, Silbermann K, Pahnke J, Wiese M, Stefan SM (2021)
Scaffold fragmentation and substructure hopping reveal potential, robustness, and limits of computer-aided pattern analysis (C@PA)
Comput Struct Biotechnol J, 19, 3269-3283
DOI 10.1016/j.csbj.2021.05.018, PubMed 34141145

Namasivayam V, Silbermann K, Wiese M, Pahnke J, Stefan SM (2021)
C@PA: Computer-Aided Pattern Analysis to Predict Multitarget ABC Transporter Inhibitors
J Med Chem, 64 (6), 3350-3366
DOI 10.1021/acs.jmedchem.0c02199, PubMed 33724808

Namasivayam V, Stefan K, Pahnke J, Stefan SM (2021)
Binding mode analysis of ABCA7 for the prediction of novel Alzheimer's disease therapeutics
Comput Struct Biotechnol J, 19, 6490-6504
DOI 10.1016/j.csbj.2021.11.035, PubMed 34976306

Nast A, Smith C, Spuls PI, Avila Valle G, Bata-Csörgö Z, Boonen H, De Jong E, Garcia-Doval I, Gisondi P, Kaur-Knudsen D, Mahil S, Mälkönen T, Maul JT, Mburu S, Mrowietz U, Reich K, Remenyik E, Rønholt KM, Sator PG, Schmitt-Egenolf M, Sikora M, Strömer K, Sundnes O, Trigos D, Van Der Kraaij G et al. (2021)
EuroGuiDerm Guideline on the systemic treatment of Psoriasis vulgaris - Part 2: specific clinical and comorbid situations
J Eur Acad Dermatol Venereol, 35 (2), 281-317
DOI 10.1111/jdv.16926, PubMed 33547728

Nedberg NH, Turowski G, Guz K, Przytuła E, Uhrynowska M, Roald B, Husebekk A, Sitras V, Nystad M, Dębska M, Brojer E, Tiller H (2021)
Platelet alloimmunization is associated with low grade chronic histiocytic intervillositis - A new link to a rare placental lesion?
Placenta, 112, 89-96
DOI 10.1016/j.placenta.2021.07.291, PubMed 34329972

Nikolic S, Ghorbani P, Pozzi Mucelli R, Ghazi S, Baldaque-Silva F, Del Chiaro M, Sparrelid E, Verbeke CS, Löhr JM, Vujasinovic M (2021)
Surgery in Autoimmune Pancreatitis
Dig Surg, 39 (1), 32-41
DOI 10.1159/000521490, PubMed 34915509

Nobre AR, Risson E, Singh DK, Di Martino JS, Cheung JF, Wang J, Johnson J, Russnes HG, Bravo-Cordero JJ, Birbrair A, Naume B, Azhar M, Frenette PS, Aguirre-Ghiso JA (2021)
Bone marrow NG2+/Nestin+ mesenchymal stem cells drive DTC dormancy via TGFβ2
Nat Cancer, 2 (3), 327-339
DOI 10.1038/s43018-021-00179-8, PubMed 34993493

Nordeng J, Schandiz H, Solheim S, Åkra S, Hoffman P, Roald B, Bendz B, Arnesen H, Helseth R, Seljeflot I (2021)
The Inflammasome Signaling Pathway Is Actively Regulated and Related to Myocardial Damage in Coronary Thrombi from Patients with STEMI
Mediators Inflamm, 2021, 5525917
DOI 10.1155/2021/5525917, PubMed 34135690

Pahnke J, Bascuñana P, Brackhan M, Stefan K, Namasivayam V, Koldamova R, Wu J, Möhle L, Stefan SM (2021)
Strategies to gain novel Alzheimer's disease diagnostics and therapeutics using modulators of ABCA transporters
Free Neuropathol, 2
DOI 10.17879/freeneuropathology-2021-3528, PubMed 34977908

Panagopoulos I, Andersen K, Ramslien LF, Ikonomou IM, Micci F, Heim S (2021)
Therapy-related Myeloid Leukemia With the Translocation t(8;19)(p11;q13) Leading to a KAT6A-LEUTX Fusion Gene
Anticancer Res, 41 (4), 1753-1760
DOI 10.21873/anticanres.14940, PubMed 33813379

Panagopoulos I, Gorunova L, Andersen K, Lobmaier I, Heim S (2021)
Several Fusion Genes Identified in a Spermatic Cord Leiomyoma With Rearrangements of Chromosome Arms 3p and 21q
Cancer Genomics Proteomics, 18 (4), 531-542
DOI 10.21873/cgp.20278, PubMed 34183386

Panagopoulos I, Gorunova L, Andersen K, Lund-Iversen M, Tafjord S, Micci F, Heim S (2021)
Fusion of the Paired Box 3 (PAX3) and Myocardin (MYOCD) Genes in Pediatric Rhabdomyosarcoma
Cancer Genomics Proteomics, 18 (6), 723-734
DOI 10.21873/cgp.20293, PubMed 34697065

Panagopoulos I, Gorunova L, Lund-Iversen M, Heim S (2021)
Monosomy 13 in Mammary Myofibroblastoma
Anticancer Res, 41 (8), 3747-3751
DOI 10.21873/anticanres.15166, PubMed 34281833

Pandey S, Søland TM, Bjerkli IH, Sand LP, Petersen FC, Costea DE, Senguven B, Sapkota D (2021)
Combined loss of expression of involucrin and cytokeratin 13 is associated with poor prognosis in squamous cell carcinoma of mobile tongue
Head Neck, 43 (11), 3374-3385
DOI 10.1002/hed.26826, PubMed 34338386

Rasmussen LG, Verbeke CS, Sørensen MD, Pfeiffer P, Tan Q, Mortensen MB, Fristrup C, Detlefsen S (2021)
Gene expression profiling of morphologic subtypes of pancreatic ductal adenocarcinoma using surgical and EUS-FNB specimens
Pancreatology, 21 (3), 530-543
DOI 10.1016/j.pan.2021.01.025, PubMed 33637450

Reimers A, Hummel CA, Eis-Hübinger AM, Surges R, Niehusmann P, Schoch S, Becker AJ, Pitsch J (2021)
Analysis of autoantibody spectrum and human herpesvirus 6 in adult patients with 'early' versus 'late' diagnosis of 'possible limbic encephalitis'
Epilepsy Res, 176, 106698
DOI 10.1016/j.eplepsyres.2021.106698, PubMed 34246119

Rinkevich B, Ballarin L, Martinez P, Somorjai I, Ben-Hamo O, Borisenko I, Berezikov E, Ereskovsky A, Gazave E, Khnykin D, Manni L, Petukhova O, Rosner A, Röttinger E, Spagnuolo A, Sugni M, Tiozzo S, Hobmayer B (2021)
A pan-metazoan concept for adult stem cells: the wobbling Penrose landscape
Biol Rev Camb Philos Soc, 97 (1), 299-325
DOI 10.1111/brv.12801, PubMed 34617397

Ruiz de Garibay G, García de Jalón E, Stigen E, Lund KB, Popa M, Davidson B, Safont MM, Rygh CB, Espedal H, Barrett TM, Haug BE, McCormack E (2021)
Repurposing 18F-FMISO as a PET tracer for translational imaging of nitroreductase-based gene directed enzyme prodrug therapy
Theranostics, 11 (12), 6044-6057
DOI 10.7150/thno.55092, PubMed 33897898

Rye IH, Huse K, Josefsson SE, Kildal W, Danielsen HE, Schlichting E, Garred Ø, Riis ML, Osbreac, Lingjaerde OC, Myklebust JH, Russnes HG (2021)
Breast cancer metastasis: immune profiling of lymph nodes reveals exhaustion of effector T cells and immunosuppression
Mol Oncol, 16 (1), 88-103
DOI 10.1002/1878-0261.13047, PubMed 34165864

Sahakyan MA, Verbeke CS, Tholfsen T, Ignjatovic D, Kleive D, Buanes T, Lassen K, Røsok BI, Labori KJ, Edwin B (2021)
Prognostic Impact of Resection Margin Status in Distal Pancreatectomy for Ductal Adenocarcinoma
Ann Surg Oncol, 29 (1), 366-375
DOI 10.1245/s10434-021-10464-6, PubMed 34296358

Sanegre S, Eritja N, de Andrea C, Diaz-Martin J, Diaz-Lagares Á, Jácome MA, Salguero-Aranda C, García Ros D, Davidson B, Lopez R, Melero I, Navarro S, Ramon Y Cajal S, de Alava E, Matias-Guiu X, Noguera R (2021)
Characterizing the Invasive Tumor Front of Aggressive Uterine Adenocarcinoma and Leiomyosarcoma
Front Cell Dev Biol, 9, 670185
DOI 10.3389/fcell.2021.670185, PubMed 34150764

Sántha P, Lenggenhager D, Finstadsveen A, Dorg L, Tøndel K, Amrutkar M, Gladhaug IP, Verbeke C (2021)
Morphological Heterogeneity in Pancreatic Cancer Reflects Structural and Functional Divergence
Cancers (Basel), 13 (4)
DOI 10.3390/cancers13040895, PubMed 33672734

Sapkota D, Sharma S, Søland TM, Braz-Silva PH, Teh MT (2021)
Expression profile of SARS-CoV-2 cellular entry proteins in normal oral mucosa and oral squamous cell carcinoma
Clin Exp Dent Res, 8 (1), 117-122
DOI 10.1002/cre2.510, PubMed 34726347

Sioud M, Juzenas P, Zhang Q, Kleinauskas A, Peng Q (2021)
Evaluation of In Vitro Phototoxicity of a Minibody-IR700 Conjugate Using Cell Monolayer and Multicellular Tumor Spheroid Models
Cancers (Basel), 13 (13)
DOI 10.3390/cancers13133356, PubMed 34283089

Slørdahl KS, Klotz D, Olsen JÅ, Skovlund E, Undseth C, Abildgaard HL, Brændengen M, Nesbakken A, Larsen SG, Hanekamp BA, Holmboe L, Tvedt R, Sveen A, Lothe RA, Malinen E, Kaasa S, Guren MG (2021)
Treatment outcomes and prognostic factors after chemoradiotherapy for anal cancer
Acta Oncol, 60 (7), 921-930
DOI 10.1080/0284186X.2021.1918763, PubMed 33966592

Soer EC, Verbeke CS (2021)
Pathology reporting of margin status in locally advanced pancreatic cancer: challenges and uncertainties
J Gastrointest Oncol, 12 (5), 2512-2520
DOI 10.21037/jgo-20-391, PubMed 34790412

Solhaug MB, Schreurs O, Schenck K, Blix IJ, Baekkevold ES (2021)
Origin of langerin (CD207)-expressing antigen presenting cells in the normal oral mucosa and in oral lichen planus lesions
Eur J Oral Sci, 130 (1), e12835
DOI 10.1111/eos.12835, PubMed 34935212

Stenberg VY, Larsen RH, Ma LW, Peng Q, Juzenas P, Bruland ØS, Juzeniene A (2021)
Evaluation of the PSMA-Binding Ligand 212Pb-NG001 in Multicellular Tumour Spheroid and Mouse Models of Prostate Cancer
Int J Mol Sci, 22 (9)
DOI 10.3390/ijms22094815, PubMed 34062920

Sundnes O, Ottestad W, Schjalm C, Lundbäck P, la Cour Poulsen L, Mollnes TE, Haraldsen G, Eken T (2021)
Rapid systemic surge of IL-33 after severe human trauma: a prospective observational study
Mol Med, 27 (1), 29
DOI 10.1186/s10020-021-00288-1, PubMed 33771098

Svendsen HA, Meling TR, Nygaard V, Waagene S, Russnes H, Juell S, Rogne SG, Pahnke J, Helseth E, Fodstad Ø, Maelandsmo GM (2021)
Novel human melanoma brain metastasis models in athymic nude fox1nu mice: Site-specific metastasis patterns reflecting their clinical origin
Cancer Med, 10 (23), 8604-8613
DOI 10.1002/cam4.4334, PubMed 34612023

Switlyk MD, Niehusmann P, Sprauten M, Magelssen H, Aarhus M, Rasmussen FØ, Knutstad K, Brandal P (2021)
Neurosarcoidosis resembling multiple meningiomas: A misleading presentation of the disease and diagnostic challenge
Acta Radiol Open, 10 (7), 20584601211036550
DOI 10.1177/20584601211036550, PubMed 34377543

Szodoray P, Andersen TK, Heinzelbecker J, Imbery JF, Huszthy PC, Stanford SM, Bogen B, Landsverk OB, Bottini N, Tveita A, Munthe LA, Nakken B (2021)
Integration of T helper and BCR signals governs enhanced plasma cell differentiation of memory B cells by regulation of CD45 phosphatase activity
Cell Rep, 36 (6), 109525
DOI 10.1016/j.celrep.2021.109525, PubMed 34380042

Søfteland S, Sebitloane MH, Taylor M, Roald BB, Holmen S, Galappaththi-Arachchige HN, Gundersen SG, Kjetland EF (2021)
A systematic review of handheld tools in lieu of colposcopy for cervical neoplasia and female genital schistosomiasis
Int J Gynaecol Obstet, 153 (2), 190-199
DOI 10.1002/ijgo.13538, PubMed 33316096

Talwelkar SS, Mäyränpää MI, Søraas L, Potdar S, Bao J, Hemmes A, Linnavirta N, Lømo J, Räsänen J, Knuuttila A, Wennerberg K, Verschuren EW (2021)
Functional diagnostics using fresh uncultured lung tumor cells to guide personalized treatments
Cell Rep Med, 2 (8), 100373
DOI 10.1016/j.xcrm.2021.100373, PubMed 34467250

Tryggestad AMA, Axcrona K, Axcrona U, Bigalke I, Brennhovd B, Inderberg EM, Hønnåshagen TK, Skoge LJ, Solum G, Saebøe-Larssen S, Josefsen D, Olaussen RW, Aamdal S, Skotheim RI, Myklebust TÅ, Schendel DJ, Lilleby W, Dueland S, Kvalheim G (2021)
Long-term first-in-man Phase I/II study of an adjuvant dendritic cell vaccine in patients with high-risk prostate cancer after radical prostatectomy
Prostate, 82 (2), 245-253
DOI 10.1002/pros.24267, PubMed 34762317

Tulipan AJ, Salberg UB, Hole KH, Vlatkovic L, Aarnes EK, Revheim ME, Lyng H, Seierstad T (2021)
Amino acid transporter expression and 18F-FACBC uptake at PET in primary prostate cancer
Am J Nucl Med Mol Imaging, 11 (4), 250-259
PubMed 34513278

Upīte J, Brüning T, Möhle L, Brackhan M, Bascuñana P, Jansone B, Pahnke J (2021)
A New Tool for the Analysis of the Effect of Intracerebrally Injected Anti-Amyloid-β Compounds
J Alzheimers Dis, 84 (4), 1677-1690
DOI 10.3233/JAD-215180, PubMed 34719500

Venizelos A, Elvebakken H, Perren A, Nikolaienko O, Deng W, Lothe IMB, Couvelard A, Hjortland GO, Sundlöv A, Svensson J, Garresori H, Kersten C, Hofsli E, Detlefsen S, Krogh M, Sorbye H, Knappskog S (2021)
The molecular characteristics of high-grade gastroenteropancreatic neuroendocrine neoplasms
Endocr Relat Cancer, 29 (1), 1-14
DOI 10.1530/ERC-21-0152, PubMed 34647903

Verbeke C, Webster F, Brosens L, Campbell F, Del Chiaro M, Esposito I, Feakins RM, Fukushima N, Gill AJ, Kakar S, Kench JG, Krasinskas AM, van Laethem JL, Schaeffer DF, Washington K (2021)
Dataset for the reporting of carcinoma of the exocrine pancreas: recommendations from the International Collaboration on Cancer Reporting (ICCR)
Histopathology, 79 (6), 902-912
DOI 10.1111/his.14540, PubMed 34379823

Vujanić GM, D'Hooghe E, Graf N, Vokuhl C, Al-Saadi R, Chowdhury T, Pritchard-Jones K, Furtwängler R (2021)
Prognostic significance of histopathological response to preoperative chemotherapy in unilateral Wilms' tumor: An analysis of 899 patients treated on the SIOP WT 2001 protocol in the UK-CCLG and GPOH studies
Int J Cancer, 149 (6), 1332-1340
DOI 10.1002/ijc.33707, PubMed 34109628

Vujanić GM, D'Hooghe E, Vokuhl C, Collini P (2021)
Dataset for the reporting of nephrectomy specimens for Wilms' tumour treated with preoperative chemotherapy: recommendations from the International Society of Paediatric Oncology Renal Tumour Study Group
Histopathology, 79 (5), 678-686
DOI 10.1111/his.14394, PubMed 33942359

Wahl SGF, Dai HY, Emdal EF, Berg T, Halvorsen TO, Ottestad AL, Lund-Iversen M, Brustugun OT, Førde D, Paulsen EE, Donnem T, Andersen S, Grønberg BH, Richardsen E (2021)
The Prognostic Effect of KRAS Mutations in Non-Small Cell Lung Carcinoma Revisited: A Norwegian Multicentre Study
Cancers (Basel), 13 (17)
DOI 10.3390/cancers13174294, PubMed 34503114

Wiedmann M, Skattør T, Stray-Pedersen A, Romundstad L, Antal EA, Marthinsen PB, Sørvoll IH, Leiknes Ernstsen S, Lund CG, Holme PA, Johansen TO, Brunborg C, Aamodt AH, Schultz NH, Skagen K, Skjelland M (2021)
Vaccine Induced Immune Thrombotic Thrombocytopenia Causing a Severe Form of Cerebral Venous Thrombosis With High Fatality Rate: A Case Series
Front Neurol, 12, 721146
DOI 10.3389/fneur.2021.721146, PubMed 34393988

Wik JA, Phung D, Kolan S, Haraldsen G, Skålhegg BS, Hol Fosse J (2021)
Inflammatory activation of endothelial cells increases glycolysis and oxygen consumption despite inhibiting cell proliferation
FEBS Open Bio, 11 (6), 1719-1730
DOI 10.1002/2211-5463.13174, PubMed 33979025

Zhou W, Xu C, Dong G, Qiao H, Yang J, Liu H, Ding L, Sun K, Zhao W (2021)
Development of phenyltriazole thiol-based derivatives as highly potent inhibitors of DCN1-UBC12 interaction
Eur J Med Chem, 217, 113326
DOI 10.1016/j.ejmech.2021.113326, PubMed 33756127

Zosen D, Austdal LPE, Bjørnstad S, Lumor JS, Paulsen RE (2021)
Antiepileptic drugs lamotrigine and valproate differentially affect neuronal maturation in the developing chick embryo, yet with PAX6 as a potential common mediator
Neurotoxicol Teratol, 90, 107057
DOI 10.1016/j.ntt.2021.107057, PubMed 34942343

Aamdal E, Jacobsen KD, Straume O, Kersten C, Herlofsen O, Karlsen J, Hussain I, Amundsen A, Dalhaug A, Nyakas M, Schuster C, Hagene KT, Holmsen K, Russnes HG, Skovlund E, Kaasa S, Aamdal S, Kyte JA, Guren TK (2021)
Ipilimumab in a real-world population: A prospective Phase IV trial with long-term follow-up
Int J Cancer, 150 (1), 100-111
DOI 10.1002/ijc.33768, PubMed 34449877

0.18s