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Publications (original articles or review articles) published in 2022 from OUS - Department of Pharmacology

35 publications found

Akbar R, Bashour H, Rawat P, Robert PA, Smorodina E, Cotet TS, Flem-Karlsen K, Frank R, Mehta BB, Vu MH, Zengin T, Gutierrez-Marcos J, Lund-Johansen F, Andersen JT, Greiff V (2022)
Progress and challenges for the machine learning-based design of fit-for-purpose monoclonal antibodies
MAbs, 14 (1), 2008790
DOI 10.1080/19420862.2021.2008790, PubMed 35293269

Bialer M, Johannessen SI, Koepp MJ, Levy RH, Perucca E, Perucca P, Tomson T, White HS (2022)
Progress report on new antiepileptic drugs: A summary of the Sixteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVI): I. Drugs in preclinical and early clinical development
Epilepsia, 63 (11), 2865-2882
DOI 10.1111/epi.17373, PubMed 35946083

Bialer M, Johannessen SI, Koepp MJ, Levy RH, Perucca E, Perucca P, Tomson T, White HS (2022)
Progress report on new antiepileptic drugs: A summary of the Sixteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVI): II. Drugs in more advanced clinical development
Epilepsia, 63 (11), 2883-2910
DOI 10.1111/epi.17376, PubMed 35950617

Bjørnebekk A, Scarth M, Neupane SP, Westlye LT, Hullstein IR, Thorsby PM, Halvorsen B (2022)
Use of High-Dose Androgens Is Associated with Reduced Brain-Derived Neurotrophic Factor in Male Weightlifters
Neuroendocrinology, 113 (1), 36-47
DOI 10.1159/000526418, PubMed 35944495

Brunvoll SH, Nygaard AB, Ellingjord-Dale M, Holland P, Istre MS, Kalleberg KT, Søraas CL, Holven KB, Ulven SM, Hjartåker A, Haider T, Lund-Johansen F, Dahl JA, Meyer HE, Søraas A (2022)
Prevention of covid-19 and other acute respiratory infections with cod liver oil supplementation, a low dose vitamin D supplement: quadruple blinded, randomised placebo controlled trial
BMJ, 378, e071245
DOI 10.1136/bmj-2022-071245, PubMed 36215222

Bækken LV, Holden G, Gjelstad A, Lauritzen F (2022)
Ten years of collecting hematological athlete biological passport samples-perspectives from a National Anti-doping Organization
Front Sports Act Living, 4, 954479
DOI 10.3389/fspor.2022.954479, PubMed 35928963

Calamera G, Moltzau LR, Levy FO, Andressen KW (2022)
Phosphodiesterases and Compartmentation of cAMP and cGMP Signaling in Regulation of Cardiac Contractility in Normal and Failing Hearts
Int J Mol Sci, 23 (4)
DOI 10.3390/ijms23042145, PubMed 35216259

Doglio M, Crossland RE, Alho AC, Penack O, Dickinson AM, Stary G, Lacerda JF, Eissner G, Inngjerdingen M (2022)
Cell-based therapy in prophylaxis and treatment of chronic graft-versus-host disease
Front Immunol, 13, 1045168
DOI 10.3389/fimmu.2022.1045168, PubMed 36466922

Faleeva M, Diakonov I, Srivastava P, Ramuz M, Calamera G, Andressen KW, Bork N, Tsansizi L, Cosson MV, Bernardo AS, Nikolaev V, Gorelik J (2022)
Compartmentation of cGMP Signaling in Induced Pluripotent Stem Cell Derived Cardiomyocytes during Prolonged Culture
Cells, 11 (20)
DOI 10.3390/cells11203257, PubMed 36291124

Foss S, Jonsson A, Bottermann M, Watkinson R, Lode HE, McAdam MB, Michaelsen TE, Sandlie I, James LC, Andersen JT (2022)
Potent TRIM21 and complement-dependent intracellular antiviral immunity requires the IgG3 hinge
Sci Immunol, 7 (70), eabj1640
DOI 10.1126/sciimmunol.abj1640, PubMed 35486676

Gjølberg TT, Frick R, Mester S, Foss S, Grevys A, Høydahl LS, Jørstad ØK, Schlothauer T, Sandlie I, Moe MC, Andersen JT (2022)
Biophysical differences in IgG1 Fc-based therapeutics relate to their cellular handling, interaction with FcRn and plasma half-life
Commun Biol, 5 (1), 832
DOI 10.1038/s42003-022-03787-x, PubMed 35982144

Halvorsen LV, Bergland OU, Søraas CL, Larstorp ACK, Hjørnholm U, Kjær VN, Kringen MK, Clasen PE, Haldsrud R, Kjeldsen SE, Rostrup M, Fadl Elmula FEM, Opdal MS, Høieggen A (2022)
Nonadherence by Serum Drug Analyses in Resistant Hypertension: 7-Year Follow-Up of Patients Considered Adherent by Directly Observed Therapy
J Am Heart Assoc, 11 (18), e025879
DOI 10.1161/JAHA.121.025879, PubMed 36073648

Henning O, Alfstad KÅ, Johannessen Landmark C, Helmstaedter C, Lossius MI, Holth Skogan A (2022)
Use of screening tools to assess comorbidities and adverse events in patients with epilepsy. A European Reference Network for Rare and Complex Epilepsies (EpiCARE) survey
Seizure, 101, 237-243
DOI 10.1016/j.seizure.2022.09.008, PubMed 36115293

Larsen RE, Pripp AH, Krogstad T, Johannessen Landmark C, Holm LB (2022)
Development and validation of a new non-disease-specific survey tool to assess self-reported adherence to medication
Front Pharmacol, 13, 981368
DOI 10.3389/fphar.2022.981368, PubMed 36569319

Larsson D, Baftiu A, Johannessen Landmark C, von Euler M, Kumlien E, Åsberg S, Zelano J (2022)
Association Between Antiseizure Drug Monotherapy and Mortality for Patients With Poststroke Epilepsy
JAMA Neurol, 79 (2), 169-175
DOI 10.1001/jamaneurol.2021.4584, PubMed 34902006

Lemaitre F, Budde K, Van Gelder T, Bergan S, Lawson R, Noceti O, Venkataramanan R, Elens L, Moes DJAR, Hesselink DA, Pawinski T, Johnson-Davis KL, De Winter BCM, Pattanaik S, Brunet M, Masuda S, Langman LJ (2022)
Therapeutic drug monitoring and dosage adjustments of immunosuppressive drugs when combined with nirmatrelvir/ritonavir in patients with COVID-19
Ther Drug Monit (in press)
DOI 10.1097/FTD.0000000000001014, PubMed 35944126

Levay MK, Krobert KA, Vogt A, Ahmad A, Jungmann A, Neuber C, Pasch S, Hansen A, Müller OJ, Lutz S, Wieland T (2022)
RGS3L allows for an M₂ muscarinic receptor-mediated RhoA-dependent inotropy in cardiomyocytes
Basic Res Cardiol, 117 (1), 8
DOI 10.1007/s00395-022-00915-w, PubMed 35230541

Ljungblad UW, Lindberg M, Eklund EA, Sæves I, Sagredo C, Bjørke-Monsen AL, Tangeraas T (2022)
A Retrospective Evaluation of the Predictive Value of Newborn Screening for Vitamin B12 Deficiency in Symptomatic Infants Below 1 Year of Age
Int J Neonatal Screen, 8 (4)
DOI 10.3390/ijns8040066, PubMed 36547383

Manfra O, Calamera G, Froese A, Arunthavarajah D, Surdo NC, Meier S, Melleby AO, Aasrum M, Aronsen JM, Nikolaev VO, Zaccolo M, Moltzau LR, Levy FO, Andressen KW (2022)
CNP regulates cardiac contractility and increases cGMP near both SERCA and TnI: difference from BNP visualized by targeted cGMP biosensors
Cardiovasc Res, 118 (6), 1506-1519
DOI 10.1093/cvr/cvab167, PubMed 33970224

Müller LD, Føreid S (2022)
A comparison of an optimized automated sample preparation of PEth in blood pretreated by freezing versus manual preparation in whole blood, analyzing by UHPLC - MS/MS
J Pharm Biomed Anal, 212, 114635
DOI 10.1016/j.jpba.2022.114635, PubMed 35152009

Pisana A, Wettermark B, Kurdi A, Tubic B, Pontes C, Zara C, Van Ganse E, Petrova G, Mardare I, Fürst J, Roig-Izquierdo M, Melien O, Bonanno PV, Banzi R, Marković-Peković V, Mitkova Z, Godman B (2022)
Challenges and Opportunities With Routinely Collected Data on the Utilization of Cancer Medicines. Perspectives From Health Authority Personnel Across 18 European Countries
Front Pharmacol, 13, 873556
DOI 10.3389/fphar.2022.873556, PubMed 35865969

Revdal E, Morken G, Bakken IJ, Bråthen G, Landmark CJ, Brodtkorb E (2022)
Bidirectionality of antiseizure and antipsychotic treatment: A population-based study
Epilepsy Behav, 136, 108911
DOI 10.1016/j.yebeh.2022.108911, PubMed 36126553

Sand KMK, Gruber MM, Sandlie I, Mathiesen L, Andersen JT, Wadsack C (2022)
Contribution of the ex vivo placental perfusion model in understanding transplacental immunoglobulin G transfer
Placenta, 127, 77-87
DOI 10.1016/j.placenta.2022.07.019, PubMed 35981406

Scarth M, Jørstad ML, Reierstad A, Klonteig S, Torgersen S, Hullstein IR, Bjørnebekk A (2022)
Psychopathology among anabolic-androgenic steroid using and non-using female athletes in Norway
J Psychiatr Res, 155, 295-301
DOI 10.1016/j.jpsychires.2022.09.023, PubMed 36170757

Skogestad J, Aronsen JM (2022)
Regulation of Cardiac Contractility by the Alpha 2 Subunit of the Na⁺/K⁺-ATPase
Front Physiol, 13, 827334
DOI 10.3389/fphys.2022.827334, PubMed 35812308

Sudworth A, Segers FM, Yilmaz B, Guslund NC, Macpherson AJ, Dissen E, Qiao SW, Inngjerdingen M (2022)
Innate lymphoid cell characterization in the rat and their correlation to gut commensal microbes
Eur J Immunol, 52 (5), 717-729
DOI 10.1002/eji.202149639, PubMed 35099074

Svendsen T, Brodtkorb E, Linge HL, Burns ML, Johannessen SI, Nakken KO, Lossius MI, Landmark CJ (2022)
Efficacy, tolerability and pharmacokinetic variability of brivaracetam in adults with difficult-to-treat epilepsy
Epilepsy Res, 183, 106946
DOI 10.1016/j.eplepsyres.2022.106946, PubMed 35609355

Søraas A, Grødeland G, Granerud BK, Ueland T, Lind A, Fevang B, Murphy SL, Huse C, Nygaard AB, Steffensen AK, Al-Baldawi H, Holberg-Petersen M, Andresen LL, Ågnes C, Ranheim T, Schanke Y, Istre M, Dahl JA, Chopra A, Dudman S, Kaarbø M, Andersen JT, Vaage EB, Tran TT, Vaage JT et al. (2022)
Breakthrough infections with the omicron and delta variants of SARS-CoV-2 result in similar re-activation of vaccine-induced immunity
Front Immunol, 13, 964525
DOI 10.3389/fimmu.2022.964525, PubMed 36159859

Thorstensen CW, Clasen PE, Rognstad S, Haldsrud R, Føreid S, Helstrøm T, Bergland OU, Halvorsen LV, Aune A, Olsen E, Brobak KM, Høieggen A, Gustavsen I, Larstorp ACK, Søraas CL, Opdal MS (2022)
Development of UHPLC-MS/MS methods to quantify 25 antihypertensive drugs in serum in a cohort of patients treated for hypertension
J Pharm Biomed Anal, 219, 114908
DOI 10.1016/j.jpba.2022.114908, PubMed 35803015

Tran TT, Vaage EB, Mehta A, Chopra A, Tietze L, Kolderup A, Anthi A, König M, Nygaard G, Lind A, Müller F, Nissen-Meyer LS, Magnus P, Trogstad L, Mjaaland S, Søraas A, Midtvedt K, Åsberg A, Barratt-Due A, Medhus AW, Høivik ML, Lundin K, Karlsen RF, Dahle R, Danielsson K et al. (2022)
Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants
NPJ Vaccines, 7 (1), 174
DOI 10.1038/s41541-022-00586-7, PubMed 36585405

Vethe NT, Husebye E, Andersen AM, Bergan S, Kristiansen O, Fagerland MW, Munkhaugen J (2022)
Monitoring Simvastatin Adherence in Patients With Coronary Heart Disease: A Proof-of-Concept Study Based on Pharmacokinetic Measurements in Blood Plasma
Ther Drug Monit, 44 (4), 558-567
DOI 10.1097/FTD.0000000000000992, PubMed 35482468

Westergren T, Narum S, Klemp M (2022)
Biases in reporting of adverse effects in clinical trials, and potential impact on safety assessments in systematic reviews and therapy guidelines
Basic Clin Pharmacol Toxicol, 131 (6), 465-473
DOI 10.1111/bcpt.13791, PubMed 36125975

Zakrzewicz A, Würth C, Beckert B, Feldhoff S, Vanderheyden K, Foss S, Andersen JT, Haard H, Verheesen P, Bobkov V, Tikkanen R (2022)
Stabilization of Keratinocyte Monolayer Integrity in the Presence of Anti-Desmoglein-3 Antibodies through FcRn Blockade with Efgartigimod: Novel Treatment Paradigm for Pemphigus?
Cells, 11 (6)
DOI 10.3390/cells11060942, PubMed 35326398

Åbjørsbråten KS, Skaaraas GHES, Cunen C, Bjørnstad DM, Binder KMG, Bojarskaite L, Jensen V, Nilsson LNG, Rao SB, Tang W, Hermansen GH, Nagelhus EA, Ottersen OP, Torp R, Enger R (2022)
Impaired astrocytic Ca²⁺ signaling in awake-behaving Alzheimer's disease transgenic mice
Elife, 11
DOI 10.7554/eLife.75055, PubMed 35833623

Aarsund M, Segers FM, Wu Y, Inngjerdingen M (2022)
Comparison of characteristics and tumor targeting properties of extracellular vesicles derived from primary NK cells or NK-cell lines stimulated with IL-15 or IL-12/15/18
Cancer Immunol Immunother, 71 (9), 2227-2238
DOI 10.1007/s00262-022-03161-0, PubMed 35119498