Publications (original articles or review articles) published in 2023 from OUS - Department of Pharmacology
28 publications found
Novel enhancers of guanylyl cyclase-A activity acting via allosteric modulation
Br J Pharmacol, 180 (24), 3254-3270
DOI 10.1111/bph.16203, PubMed 37522273
Effectiveness and safety of everolimus treatment in patients with tuberous sclerosis complex in real-world clinical practice
Orphanet J Rare Dis, 18 (1), 377
DOI 10.1186/s13023-023-02982-1, PubMed 38042867
Complex interactions of cellular players in chronic Graft-versus-Host Disease
Front Immunol, 14, 1199422
DOI 10.3389/fimmu.2023.1199422, PubMed 37435079
Antibody blockade of Jagged1 attenuates choroidal neovascularization
Nat Commun, 14 (1), 3109
DOI 10.1038/s41467-023-38563-w, PubMed 37253747
Pharmacokinetic Variability of Sulthiame: The Impact of Age, Drug-Drug Interactions, and Biochemical Markers of Toxicity in Patients with Epilepsy
Ther Drug Monit, 46 (2), 237-245
DOI 10.1097/FTD.0000000000001146, PubMed 38158595
Middle-Aged and Older Patients With Left Ventricular Hypertrophy: Higher Mortality With Drug Treated Systolic Blood Pressure Below 130 mm Hg
Hypertension, 80 (8), 1739-1748
DOI 10.1161/HYPERTENSIONAHA.123.21454, PubMed 37350267
A two-sample approach to retrograde extrapolation of blood THC concentrations - Is it feasible?
Forensic Sci Int, 352, 111833
DOI 10.1016/j.forsciint.2023.111833, PubMed 37793282
Pharmacological aspects of antiseizure medications: From basic mechanisms to clinical considerations of drug interactions and use of therapeutic drug monitoring
Epileptic Disord, 25 (4), 454-471
DOI 10.1002/epd2.20069, PubMed 37259844
Pharmaceutical compounding and storage of faricimab in a syringe for intravitreal injection do not impair stability and bi-specific binding properties
Int J Retina Vitreous, 9 (1), 65
DOI 10.1186/s40942-023-00507-3, PubMed 37936232
Intraindividual Variability in Absolute Bioavailability and Clearance of Midazolam in Healthy Individuals
Clin Pharmacokinet, 62 (7), 981-987
DOI 10.1007/s40262-023-01257-z, PubMed 37162619
Atorvastatin Metabolite Pattern in Skeletal Muscle and Blood from Patients with Coronary Heart Disease and Statin-Associated Muscle Symptoms
Clin Pharmacol Ther, 113 (4), 887-895
DOI 10.1002/cpt.2844, PubMed 36622792
Therapeutic Drug Monitoring and Dosage Adjustments of Immunosuppressive Drugs When Combined With Nirmatrelvir/Ritonavir in Patients With COVID-19
Ther Drug Monit, 45 (2), 191-199
DOI 10.1097/FTD.0000000000001014, PubMed 35944126
Can acetate via FFA receptors contribute to the diabetogenic effect of statins?
Naunyn Schmiedebergs Arch Pharmacol, 397 (2), 1245-1248
DOI 10.1007/s00210-023-02647-7, PubMed 37642662
Disruption of the sialic acid/Siglec-9 axis improves antibody-mediated neutrophil cytotoxicity towards tumor cells
Front Immunol, 14, 1178817
DOI 10.3389/fimmu.2023.1178817, PubMed 37346044
Cytosolic antibody receptor TRIM21 is required for effective tau immunotherapy in mouse models
Science, 379 (6639), 1336-1341
DOI 10.1126/science.abn1366, PubMed 36996217
Clinical efficacy of buprenorphine after oral dosing in rats undergoing major surgery
Lab Anim, 58 (1), 34-43
DOI 10.1177/00236772231178417, PubMed 37669442
Therapeutic Salivary Monitoring of Perampanel in Patients with Epilepsy Using a Volumetric Absorptive Microsampling Technique
Pharmaceutics, 15 (8)
DOI 10.3390/pharmaceutics15082030, PubMed 37631244
Decreased serum concentrations of antiseizure medications in children with drug resistant epilepsy following treatment with ketogenic diet
Epilepsia Open, 8 (3), 858-866
DOI 10.1002/epi4.12746, PubMed 37057954
N-acetyl cysteine turns EPAC activators into potent killers of acute lymphoblastic leukemia cells
J Biol Chem, 300 (1), 105509
DOI 10.1016/j.jbc.2023.105509, PubMed 38042493
Supraphysiological testosterone levels from anabolic steroid use and reduced sensitivity to negative facial expressions in men
Psychopharmacology (Berl), 241 (4), 701-715
DOI 10.1007/s00213-023-06497-2, PubMed 37993638
Disruption of Phosphodiesterase 3A Binding to SERCA2 Increases SERCA2 Activity and Reduces Mortality in Mice With Chronic Heart Failure
Circulation, 147 (16), 1221-1236
DOI 10.1161/CIRCULATIONAHA.121.054168, PubMed 36876489
Effect of CYP2D6 and CYP2C19 genotypes on atomoxetine serum levels: A study based on therapeutic drug monitoring data
Br J Clin Pharmacol, 89 (7), 2246-2253
DOI 10.1111/bcp.15706, PubMed 36851891
Contrast Enhanced Magnetic Resonance Imaging of Amyloid-β Plaques in a Murine Alzheimer's Disease Model
J Alzheimers Dis, 93 (2), 411-419
DOI 10.3233/JAD-220198, PubMed 37038807
Plasma concentration of atorvastatin metabolites correlates with low-density lipoprotein cholesterol reduction in patients with coronary heart disease
Pharmacol Res Perspect, 11 (3), e01089
DOI 10.1002/prp2.1089, PubMed 37186070
Clinical performance of volumetric finger-prick sampling for the monitoring of tacrolimus, creatinine and haemoglobin in kidney transplant recipients
Br J Clin Pharmacol, 89 (12), 3690-3701
DOI 10.1111/bcp.15870, PubMed 37537150
Cysteine-lowering treatment with mesna against obesity: Proof of concept and results from a human phase I, dose-finding study
Diabetes Obes Metab, 25 (11), 3161-3170
DOI 10.1111/dom.15210, PubMed 37435697
Inhibition of the extracellular enzyme A disintegrin and metalloprotease with thrombospondin motif 4 prevents cardiac fibrosis and dysfunction
Cardiovasc Res, 119 (10), 1915-1927
DOI 10.1093/cvr/cvad078, PubMed 37216909
Cryo-EM of Aβ fibrils from mouse models find tg-APPArcSwe fibrils resemble those found in patients with sporadic Alzheimer's disease
Nat Neurosci, 26 (12), 2073-2080
DOI 10.1038/s41593-023-01484-4, PubMed 37973869