Publications (original articles or review articles) published in 2021 from OUS - Institute for Cancer Research
237 publications found
Wetting regulates autophagy of phase-separated compartments and the cytosol
Nature, 591 (7848), 142-146
DOI 10.1038/s41586-020-2992-3, PubMed 33473217
Re-defining synthetic lethality by phenotypic profiling for precision oncology
Cell Chem Biol, 28 (3), 246-256
DOI 10.1016/j.chembiol.2021.01.026, PubMed 33631125
T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes
Nat Biotechnol, 40 (4), 488-498
DOI 10.1038/s41587-021-01089-x, PubMed 34873326
Autophagy in healthy aging and disease
Nat Aging, 1 (8), 634-650
DOI 10.1038/s43587-021-00098-4, PubMed 34901876
Cosegregation of asymmetric features during cell division
Open Biol, 11 (8), 210116
DOI 10.1098/rsob.210116, PubMed 34343465
The Factor VII Variant p.A354V-p.P464Hfs: Clinical versus Intracellular and Biochemical Phenotypes Induced by Chemical Chaperones
Appl. Sci.-Basel, 11 (13), 5762
DOI 10.3390/app11135762
Molecular Characterization of Two Homozygous Factor VII Variants Associated with Intracranial Bleeding
Thromb Haemost, 121 (12), 1588-1598
DOI 10.1055/a-1450-8568, PubMed 33742435
Anti-Angiogenic Treatment in Pseudomyxoma Peritonei-Still a Strong Preclinical Rationale
Cancers (Basel), 13 (11)
DOI 10.3390/cancers13112819, PubMed 34198773
Photo-enhanced toxicity of crude oil on early developmental stages of Atlantic cod (Gadus morhua)
Sci Total Environ, 807 (Pt 1), 150697
DOI 10.1016/j.scitotenv.2021.150697, PubMed 34610396
Crosstalk between microRNA expression and DNA methylation drives the hormone-dependent phenotype of breast cancer
Genome Med, 13 (1), 72
DOI 10.1186/s13073-021-00880-4, PubMed 33926515
Lack of cross-resistance between non-steroidal and steroidal aromatase inhibitors in breast cancer patients: the potential role of the adipokine leptin
Breast Cancer Res Treat, 190 (3), 435-449
DOI 10.1007/s10549-021-06399-x, PubMed 34554372
Detection of phenotype-specific therapeutic vulnerabilities in breast cells using a CRISPR loss-of-function screen
Mol Oncol, 15 (8), 2026-2045
DOI 10.1002/1878-0261.12951, PubMed 33759347
Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element
Am J Hum Genet, 108 (7), 1190-1203
DOI 10.1016/j.ajhg.2021.05.013, PubMed 34146516
miRNA normalization enables joint analysis of several datasets to increase sensitivity and to reveal novel miRNAs differentially expressed in breast cancer
PLoS Comput Biol, 17 (2), e1008608
DOI 10.1371/journal.pcbi.1008608, PubMed 33566819
Comparing the epigenetic landscape in myonuclei purified with a PCM1 antibody from a fast/glycolytic and a slow/oxidative muscle
PLoS Genet, 17 (11), e1009907
DOI 10.1371/journal.pgen.1009907, PubMed 34752468
Lung Function After Stereotactic Body Radiation Therapy for Early-Stage Non-Small Cell Lung Cancer, Changes and Predictive Markers
Front Oncol, 11, 674731
DOI 10.3389/fonc.2021.674731, PubMed 34109123
Genomic and prognostic heterogeneity among RAS/BRAFV600E /TP53 co-mutated resectable colorectal liver metastases
Mol Oncol, 15 (4), 830-845
DOI 10.1002/1878-0261.12885, PubMed 33325154
Best Practices for Spatial Profiling for Breast Cancer Research with the GeoMx® Digital Spatial Profiler
Cancers (Basel), 13 (17)
DOI 10.3390/cancers13174456, PubMed 34503266
Treatment of COVID-19 Pneumonia: the Case for Placenta-derived Cell Therapy
Stem Cell Rev Rep, 17 (1), 63-70
DOI 10.1007/s12015-020-10004-x, PubMed 32696426
Uptake of circulating extracellular vesicles from rectal cancer patients and differential responses by human monocyte cultures
FEBS Open Bio, 11 (3), 724-740
DOI 10.1002/2211-5463.13098, PubMed 33512765
Whole genome copy number analyses reveal a highly aberrant genome in TP53 mutant lung adenocarcinoma tumors
BMC Cancer, 21 (1), 1089
DOI 10.1186/s12885-021-08811-7, PubMed 34625038
Improved adaptive radiotherapy to adjust for anatomical alterations during curative treatment for locally advanced lung cancer
Phys Imaging Radiat Oncol, 18, 51-54
DOI 10.1016/j.phro.2021.04.003, PubMed 34258408
Pembrolizumab in advanced osteosarcoma: results of a single-arm, open-label, phase 2 trial
Cancer Immunol Immunother, 70 (9), 2617-2624
DOI 10.1007/s00262-021-02876-w, PubMed 33580363
Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women
N Engl J Med, 384 (5), 428-439
DOI 10.1056/NEJMoa1913948, PubMed 33471991
E-cadherin is a robust prognostic biomarker in colorectal cancer and low expression is associated with sensitivity to inhibitors of topoisomerase, aurora, and HSP90 in preclinical models
Mol Oncol, 16 (12), 2312-2329
DOI 10.1002/1878-0261.13159, PubMed 34890102
Machine Learning of Bone Marrow Histopathology Identifies Genetic and Clinical Determinants in Patients with MDS
Blood Cancer Discov, 2 (3), 238-249
DOI 10.1158/2643-3230.BCD-20-0162, PubMed 34661156
Lipotoxic stress alters the membrane lipid profile of extracellular vesicles released by Huh-7 hepatocarcinoma cells
Sci Rep, 11 (1), 4613
DOI 10.1038/s41598-021-84268-9, PubMed 33633289
Gene Regulation Network Analysis on Human Prostate Orthografts Highlights a Potential Role for the JMJD6 Regulon in Clinical Prostate Cancer
Cancers (Basel), 13 (9)
DOI 10.3390/cancers13092094, PubMed 33925994
Pharmacologic Control of CAR T Cells
Int J Mol Sci, 22 (9)
DOI 10.3390/ijms22094320, PubMed 33919245
The Presence of Activated T Cell Subsets prior to Transplantation Is Associated with Increased Rejection Risk in Pancreas Transplant Recipients
J Immunol, 207 (10), 2501-2511
DOI 10.4049/jimmunol.2001103, PubMed 34607938
From Plant to Patient: Thapsigargin, a Tool for Understanding Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy, ATPases, Cell Death, and Drug Development
Prog Chem Org Nat Prod, 115, 59-114
DOI 10.1007/978-3-030-64853-4_2, PubMed 33797641
Reactive Species from Two-Signal Activated Macrophages Interfere with Their Oxygen Consumption Measurements
Antioxidants (Basel), 10 (7)
DOI 10.3390/antiox10071149, PubMed 34356382
Crowdsourced mapping of unexplored target space of kinase inhibitors
Nat Commun, 12 (1), 3307
DOI 10.1038/s41467-021-23165-1, PubMed 34083538
Low Concordance Between T-Cell Densities in Matched Primary Tumors and Liver Metastases in Microsatellite Stable Colorectal Cancer
Front Oncol, 11, 671629
DOI 10.3389/fonc.2021.671629, PubMed 34178659
Single PFAS and PFAS mixtures affect nuclear receptor- and oxidative stress-related pathways in precision-cut liver slices of Atlantic cod (Gadus morhua)
Sci Total Environ, 814, 152732
DOI 10.1016/j.scitotenv.2021.152732, PubMed 34974025
The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes
Nat Commun, 12 (1), 891
DOI 10.1038/s41467-020-20670-7, PubMed 33563959
Proteomics of Mouse Heart Ventricles Reveals Mitochondria and Metabolism as Major Targets of a Post-Infarction Short-Acting GLP1Ra-Therapy
Int J Mol Sci, 22 (16)
DOI 10.3390/ijms22168711, PubMed 34445425
RasV12; scrib-/- Tumors: A Cooperative Oncogenesis Model Fueled by Tumor/Host Interactions
Int J Mol Sci, 22 (16)
DOI 10.3390/ijms22168873, PubMed 34445578
Targeting KRAS mutations with HLA class II-restricted TCRs for the treatment of solid tumors
Oncoimmunology, 10 (1), 1936757
DOI 10.1080/2162402X.2021.1936757, PubMed 34235003
No Difference in Penetrance between Truncating and Missense/Aberrant Splicing Pathogenic Variants in MLH1 and MSH2: A Prospective Lynch Syndrome Database Study
J Clin Med, 10 (13)
DOI 10.3390/jcm10132856, PubMed 34203177
Intracranial effect of osimertinib in relapsed EGFR-mutated T790M-positive and -negative non-small cell lung cancer patients: results from a phase II study
Acta Oncol, 60 (12), 1565-1571
DOI 10.1080/0284186X.2021.1973092, PubMed 34486915
The chemical defensome of five model teleost fish
Sci Rep, 11 (1), 10546
DOI 10.1038/s41598-021-89948-0, PubMed 34006915
Metastatic heterogeneity of the consensus molecular subtypes of colorectal cancer
NPJ Genom Med, 6 (1), 59
DOI 10.1038/s41525-021-00223-7, PubMed 34262039
Telomerase as a Target for Therapeutic Cancer Vaccines and Considerations for Optimizing Their Clinical Potential
Front Immunol, 12, 682492
DOI 10.3389/fimmu.2021.682492, PubMed 34290704
RAB5A expression is a predictive biomarker for trastuzumab emtansine in breast cancer
Nat Commun, 12 (1), 6427
DOI 10.1038/s41467-021-26018-z, PubMed 34741021
Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles
J Extracell Vesicles, 10 (7), e12093
DOI 10.1002/jev2.12093, PubMed 34035881
Reprogrammed transsulfuration promotes basal-like breast tumor progression via realigning cellular cysteine persulfidation
Proc Natl Acad Sci U S A, 118 (45)
DOI 10.1073/pnas.2100050118, PubMed 34737229
FANCD2 modulates the mitochondrial stress response to prevent common fragile site instability
Commun Biol, 4 (1), 127
DOI 10.1038/s42003-021-01647-8, PubMed 33514811
Rapid nanopore-based DNA sequencing protocol of antibiotic-resistant bacteria for use in surveillance and outbreak investigation
Microb Genom, 7 (4)
DOI 10.1099/mgen.0.000557, PubMed 33885360
Peptide vaccine targeting mutated GNAS: a potential novel treatment for pseudomyxoma peritonei
J Immunother Cancer, 9 (10)
DOI 10.1136/jitc-2021-003109, PubMed 34711663
Oncolytic peptides DTT-205 and DTT-304 induce complete regression and protective immune response in experimental murine colorectal cancer
Sci Rep, 11 (1), 6731
DOI 10.1038/s41598-021-86239-6, PubMed 33762676
A phase 2a randomized clinical trial of intravenous vedolizumab for the treatment of steroid-refractory intestinal acute graft-versus-host disease
Bone Marrow Transplant, 56 (10), 2477-2488
DOI 10.1038/s41409-021-01356-0, PubMed 34108672
Circadian PERformance in breast cancer: a germline and somatic genetic study of PER3VNTR polymorphisms and gene co-expression
NPJ Breast Cancer, 7 (1), 118
DOI 10.1038/s41523-021-00329-2, PubMed 34508103
V-ATPase controls tumor growth and autophagy in a Drosophila model of gliomagenesis
Autophagy, 17 (12), 4442-4452
DOI 10.1080/15548627.2021.1918915, PubMed 33978540
The Immune Landscape of Human Primary Lung Tumors Is Th2 Skewed
Front Immunol, 12, 764596
DOI 10.3389/fimmu.2021.764596, PubMed 34868011
Efficient gene expression signature for a breast cancer immuno-subtype
PLoS One, 16 (1), e0245215
DOI 10.1371/journal.pone.0245215, PubMed 33434192
Impact of the APOBEC3A/B deletion polymorphism on risk of ovarian cancer
Sci Rep, 11 (1), 23463
DOI 10.1038/s41598-021-02820-z, PubMed 34873230
Kel1 is a phosphorylation-regulated noise suppressor of the pheromone signaling pathway
Cell Rep, 37 (13), 110186
DOI 10.1016/j.celrep.2021.110186, PubMed 34965431
Assessment of Hypoxic Tissue Fraction and Prediction of Survival in Cervical Carcinoma by Dynamic Contrast-Enhanced MRI
Front Oncol, 11, 668916
DOI 10.3389/fonc.2021.668916, PubMed 34094964
Assessment of Intratumor Heterogeneity in Parametric Dynamic Contrast-Enhanced MR Images: A Comparative Study of Novel and Established Methods
Front Oncol, 11, 722773
DOI 10.3389/fonc.2021.722773, PubMed 34621674
Intravital microscopy of tumor vessel morphology and function using a standard fluorescence microscope
Eur J Nucl Med Mol Imaging, 48 (10), 3089-3100
DOI 10.1007/s00259-021-05243-0, PubMed 33606081
Clinical and molecular implications of NAB2-STAT6 fusion variants in solitary fibrous tumour
Pathology, 53 (6), 713-719
DOI 10.1016/j.pathol.2020.11.010, PubMed 33745702
Identification of a novel compound that simultaneously impairs the ubiquitin-proteasome system and autophagy
Autophagy, 18 (7), 1486-1502
DOI 10.1080/15548627.2021.1988359, PubMed 34740308
CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels
Elife, 10
DOI 10.7554/eLife.63731, PubMed 34259627
The Oslo Cyclotron Laboratory
Eur. Phys. J. Plus, 136 (2), 181
DOI 10.1140/epjp/s13360-021-01150-3
Discovery of novel candidates for anti-liposarcoma therapies by medium-scale high-throughput drug screening
PLoS One, 16 (3), e0248140
DOI 10.1371/journal.pone.0248140, PubMed 33690666
Implication of β2-adrenergic receptor and miR-196a correlation in neurite outgrowth of LNCaP prostate cancer cells
PLoS One, 16 (6), e0253828
DOI 10.1371/journal.pone.0253828, PubMed 34191854
Circulating Tumor Cell Persistence Associates with Long-Term Clinical Outcome to a Therapeutic Cancer Vaccine in Prostate Cancer
J Pers Med, 11 (7)
DOI 10.3390/jpm11070605, PubMed 34206815
Recommendations for the FAIRification of genomic track metadata
F1000Res, 10
DOI 10.12688/f1000research.28449.1, PubMed 34249331
Clinicopathological factors associated with tumour-specific mutation detection in plasma of patients with RAS-mutated or BRAF-mutated metastatic colorectal cancer
Int J Cancer, 149 (6), 1385-1397
DOI 10.1002/ijc.33672, PubMed 33961700
Survival Trends of Right- and Left-Sided Colon Cancer across Four Decades: A Norwegian Population-Based Study
Cancer Epidemiol Biomarkers Prev, 31 (2), 342-351
DOI 10.1158/1055-9965.EPI-21-0555, PubMed 34853022
Expanding roles of cell cycle checkpoint inhibitors in radiation oncology
Int J Radiat Biol, 99 (6), 941-950
DOI 10.1080/09553002.2021.1913529, PubMed 33877959
Protein Signature Predicts Response to Neoadjuvant Treatment With Chemotherapy and Bevacizumab in HER2-Negative Breast Cancers
JCO Precis Oncol, 5
DOI 10.1200/PO.20.00086, PubMed 34036235
Characterizing the Quality of Insight by Interactions: A Case Study
IEEE Trans Vis Comput Graph, 27 (8), 3410-3424
DOI 10.1109/TVCG.2020.2977634, PubMed 32142444
Impact of MDM2 promoter SNP55 (rs2870820) on risk of endometrial and ovarian cancer
Biomarkers, 26 (4), 302-308
DOI 10.1080/1354750X.2021.1891291, PubMed 33645339
Inhibition of Arenaviruses by Combinations of Orally Available Approved Drugs
Antimicrob Agents Chemother, 65 (4)
DOI 10.1128/AAC.01146-20, PubMed 33468464
Natural abundance isotope ratios to differentiate sources of carbon used during tumor growth in vivo
BMC Biol, 19 (1), 85
DOI 10.1186/s12915-021-01012-5, PubMed 33966633
Tumor Hypoxia as a Barrier in Cancer Therapy: Why Levels Matter
Cancers (Basel), 13 (3)
DOI 10.3390/cancers13030499, PubMed 33525508
True and Missed Interval Cancer in Organized Mammographic Screening: A Retrospective Review Study of Diagnostic and Prior Screening Mammograms
Acad Radiol, 29 Suppl 1, S180-S191
DOI 10.1016/j.acra.2021.03.022, PubMed 33926794
Integrating Anatomical, Molecular and Clinical Risk Factors in Gastrointestinal Stromal Tumor of the Stomach
Ann Surg Oncol, 28 (11), 6837-6845
DOI 10.1245/s10434-021-09605-8, PubMed 33651216
NIPU: a randomised, open-label, phase II study evaluating nivolumab and ipilimumab combined with UV1 vaccination as second line treatment in patients with malignant mesothelioma
J Transl Med, 19 (1), 232
DOI 10.1186/s12967-021-02905-3, PubMed 34059094
Patient-tailored design for selective co-inhibition of leukemic cell subpopulations
Sci Adv, 7 (8)
DOI 10.1126/sciadv.abe4038, PubMed 33608276
Ebulin l Is Internalized in Cells by Both Clathrin-Dependent and -Independent Mechanisms and Does Not Require Clathrin or Dynamin for Intoxication
Toxins (Basel), 13 (2)
DOI 10.3390/toxins13020102, PubMed 33573355
A simplified frailty score predicts survival and can aid treatment-intensity decisions in older patients with DLBCL
Blood Adv, 5 (22), 4771-4782
DOI 10.1182/bloodadvances.2021004777, PubMed 34543384
Multi-modal meta-analysis of cancer cell line omics profiles identifies ECHDC1 as a novel breast tumor suppressor
Mol Syst Biol, 17 (3), e9526
DOI 10.15252/msb.20209526, PubMed 33750001
The impact of tumor epithelial and microenvironmental heterogeneity on treatment responses in HER2+ breast cancer
JCI Insight, 6 (11)
DOI 10.1172/jci.insight.147617, PubMed 33886505
A Phase I/II randomized trial of H56:IC31 vaccination and adjunctive cyclooxygenase-2-inhibitor treatment in tuberculosis patients
Nat Commun, 12 (1), 6774
DOI 10.1038/s41467-021-27029-6, PubMed 34811370
Squamous cell carcinoma of the ear treated by photochemical internalization
Photodiagnosis Photodyn Ther, 36, 102528
DOI 10.1016/j.pdpdt.2021.102528, PubMed 34509683
A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis
Sci Transl Med, 13 (582)
DOI 10.1126/scitranslmed.abb0036, PubMed 33627483
COVID-19 in Cancer Patients, Risk Factors for Disease and Adverse Outcome, a Population-Based Study From Norway
Front Oncol, 11, 652535
DOI 10.3389/fonc.2021.652535, PubMed 33842366
In modern times, how important are breast cancer stage, grade and receptor subtype for survival: a population-based cohort study
Breast Cancer Res, 23 (1), 17
DOI 10.1186/s13058-021-01393-z, PubMed 33526044
Preclinical and Clinical Status of PSMA-Targeted Alpha Therapy for Metastatic Castration-Resistant Prostate Cancer
Cancers (Basel), 13 (4)
DOI 10.3390/cancers13040779, PubMed 33668474
Plasma LOX-Products and Monocyte Signaling Is Reduced by Adjunctive Cyclooxygenase-2 Inhibitor in a Phase I Clinical Trial of Tuberculosis Patients
Front Cell Infect Microbiol, 11, 669623
DOI 10.3389/fcimb.2021.669623, PubMed 34307194
A Nationwide Study of GATA2 Deficiency in Norway-the Majority of Patients Have Undergone Allo-HSCT
J Clin Immunol, 42 (2), 404-420
DOI 10.1007/s10875-021-01189-y, PubMed 34893945
MapToCleave: High-throughput profiling of microRNA biogenesis in living cells
Cell Rep, 37 (7), 110015
DOI 10.1016/j.celrep.2021.110015, PubMed 34788611
EMT-Derived Alterations in Glutamine Metabolism Sensitize Mesenchymal Breast Cells to mTOR Inhibition
Mol Cancer Res, 19 (9), 1546-1558
DOI 10.1158/1541-7786.MCR-20-0962, PubMed 34088869
Argininosuccinate lyase is a metabolic vulnerability in breast development and cancer
NPJ Syst Biol Appl, 7 (1), 36
DOI 10.1038/s41540-021-00195-5, PubMed 34535676
Analysing the attributes of Comprehensive Cancer Centres and Cancer Centres across Europe to identify key hallmarks
Mol Oncol, 15 (5), 1277-1288
DOI 10.1002/1878-0261.12950, PubMed 33734563
Host autophagy mediates organ wasting and nutrient mobilization for tumor growth
EMBO J, 40 (18), e107336
DOI 10.15252/embj.2020107336, PubMed 34309071
High expression of SCHLAP1 in primary prostate cancer is an independent predictor of biochemical recurrence, despite substantial heterogeneity
Neoplasia, 23 (6), 634-641
DOI 10.1016/j.neo.2021.05.012, PubMed 34107378
Weight Gain and the Risk of Ovarian Cancer in BRCA1 and BRCA2 Mutation Carriers
Cancer Epidemiol Biomarkers Prev, 30 (11), 2038-2043
DOI 10.1158/1055-9965.EPI-21-0296, PubMed 34426412
Early detection of complications in pancreas transplants by microdialysis catheters, an observational feasibility study
PLoS One, 16 (3), e0247615
DOI 10.1371/journal.pone.0247615, PubMed 33705460
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
Autophagy, 17 (1), 1-382
DOI 10.1080/15548627.2020.1797280, PubMed 33634751
Autophagy in major human diseases
EMBO J, 40 (19), e108863
DOI 10.15252/embj.2021108863, PubMed 34459017
PRDX-1 Supports the Survival and Antitumor Activity of Primary and CAR-Modified NK Cells under Oxidative Stress
Cancer Immunol Res, 10 (2), 228-244
DOI 10.1158/2326-6066.CIR-20-1023, PubMed 34853030
Extracellular Vesicles and Renal Fibrosis: An Odyssey toward a New Therapeutic Approach
Int J Mol Sci, 22 (8)
DOI 10.3390/ijms22083887, PubMed 33918699
Increased sensitivity to SMAC mimetic LCL161 identified by longitudinal ex vivo pharmacogenomics of recurrent, KRAS mutated rectal cancer liver metastases
J Transl Med, 19 (1), 384
DOI 10.1186/s12967-021-03062-3, PubMed 34496878
Baseline microvessel density predicts response to neoadjuvant bevacizumab treatment of locally advanced breast cancer
Sci Rep, 11 (1), 3388
DOI 10.1038/s41598-021-81914-0, PubMed 33564016
Fibroblast Growth Factor 2 Conjugated with Monomethyl Auristatin E Inhibits Tumor Growth in a Mouse Model
Biomacromolecules, 22 (10), 4169-4180
DOI 10.1021/acs.biomac.1c00662, PubMed 34542998
Chromatin and Epigenetic Dysregulation of Prostate Cancer Development, Progression, and Therapeutic Response
Cancers (Basel), 13 (13)
DOI 10.3390/cancers13133325, PubMed 34283056
The CRCbiome study: a large prospective cohort study examining the role of lifestyle and the gut microbiome in colorectal cancer screening participants
BMC Cancer, 21 (1), 930
DOI 10.1186/s12885-021-08640-8, PubMed 34407780
Bioinformatic Analysis Reveals Central Role for Tumor-Infiltrating Immune Cells in Uveal Melanoma Progression
J Immunol Res, 2021, 9920234
DOI 10.1155/2021/9920234, PubMed 34195299
A scalable solver for a stochastic, hybrid cellular automaton model of personalized breast cancer therapy
Int J Numer Method Biomed Eng, 38 (1), e3542
DOI 10.1002/cnm.3542, PubMed 34716985
New link between the RNA polymerase II-CTD and replication stress
Mol Cell Oncol, 8 (3), 1910008
DOI 10.1080/23723556.2021.1910008, PubMed 34027044
An extended APOBEC3A mutation signature in cancer
Nat Commun, 12 (1), 1602
DOI 10.1038/s41467-021-21891-0, PubMed 33707442
(Pro)renin Receptor Is a Novel Independent Prognostic Marker in Invasive Urothelial Carcinoma of the Bladder
Cancers (Basel), 13 (22)
DOI 10.3390/cancers13225642, PubMed 34830803
Impact of KRAS, BRAF and microsatellite instability status after cytoreductive surgery and HIPEC in a national cohort of colorectal peritoneal metastasis patients
Br J Cancer, 126 (5), 726-735
DOI 10.1038/s41416-021-01620-6, PubMed 34887523
Proteogenomics of non-small cell lung cancer reveals molecular subtypes associated with specific therapeutic targets and immune evasion mechanisms
Nat Cancer, 2 (11), 1224-1242
DOI 10.1038/s43018-021-00259-9, PubMed 34870237
First international workshop of the ATM and cancer risk group (4-5 December 2019)
Fam Cancer, 21 (2), 211-227
DOI 10.1007/s10689-021-00248-y, PubMed 34125377
Assessing heterogeneity in spatial data using the HTA index with applications to spatial transcriptomics and imaging
Bioinformatics, 37 (21), 3796-3804
DOI 10.1093/bioinformatics/btab569, PubMed 34358288
Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants
Genet Med, 24 (1), 119-129
DOI 10.1016/j.gim.2021.08.016, PubMed 34906479
A Novel Single-Step-Labeled 212Pb-CaCO3 Microparticle for Internal Alpha Therapy: Preparation, Stability, and Preclinical Data from Mice
Materials (Basel), 14 (23)
DOI 10.3390/ma14237130, PubMed 34885283
Improved Formulation of 224Ra-Labeled Calcium Carbonate Microparticles by Surface Layer Encapsulation and Addition of EDTMP
Pharmaceutics, 13 (5)
DOI 10.3390/pharmaceutics13050634, PubMed 33946852
Calcium Carbonate Microparticles as Carriers of 224Ra: Impact of Specific Activity in Mice with Intraperitoneal Ovarian Cancer
Curr Radiopharm, 14 (2), 145-153
DOI 10.2174/1874471013666201201102056, PubMed 33261548
Sample Preparation Approach Influences PAM50 Risk of Recurrence Score in Early Breast Cancer
Cancers (Basel), 13 (23)
DOI 10.3390/cancers13236118, PubMed 34885228
Can breast cancer be stopped? Modifiable risk factors of breast cancer among women with a prior benign or premalignant lesion
Int J Cancer, 149 (6), 1247-1256
DOI 10.1002/ijc.33680, PubMed 33990967
Tailored graphical lasso for data integration in gene network reconstruction
BMC Bioinformatics, 22 (1), 498
DOI 10.1186/s12859-021-04413-z, PubMed 34654363
Systems approach reveals distinct and shared signaling networks of the four PGE2 receptors in T cells
Sci Signal, 14 (703), eabc8579
DOI 10.1126/scisignal.abc8579, PubMed 34609894
Phosphoproteomics-Based Characterization of Prostaglandin E2 Signaling in T Cells
Mol Pharmacol, 99 (5), 370-382
DOI 10.1124/molpharm.120.000170, PubMed 33674363
Enhanced Gut-Homing Dynamics and Pronounced Exhaustion of Mucosal and Blood CD4+ T Cells in HIV-Infected Immunological Non-Responders
Front Immunol, 12, 744155
DOI 10.3389/fimmu.2021.744155, PubMed 34691047
A global analysis of the reconstitution of PTEN function by translational readthrough of PTEN pathogenic premature termination codons
Hum Mutat, 42 (5), 551-566
DOI 10.1002/humu.24186, PubMed 33600059
Omics analyses in peritoneal metastasis-utility in the management of peritoneal metastases from colorectal cancer and pseudomyxoma peritonei: a narrative review
J Gastrointest Oncol, 12 (Suppl 1), S191-S203
DOI 10.21037/jgo-20-136, PubMed 33968437
Copy number signatures predict chromothripsis and clinical outcomes in newly diagnosed multiple myeloma
Nat Commun, 12 (1), 5172
DOI 10.1038/s41467-021-25469-8, PubMed 34453055
Implementing a Functional Precision Medicine Tumor Board for Acute Myeloid Leukemia
Cancer Discov, 12 (2), 388-401
DOI 10.1158/2159-8290.CD-21-0410, PubMed 34789538
Metastases in locally advanced rectal cancer undergoing curatively intended treatment
Eur J Surg Oncol, 47 (9), 2377-2383
DOI 10.1016/j.ejso.2021.04.023, PubMed 34049768
The genetic structure of Norway
Eur J Hum Genet, 29 (11), 1710-1718
DOI 10.1038/s41431-021-00899-6, PubMed 34002043
Chromothripsis as a pathogenic driver of multiple myeloma
Semin Cell Dev Biol, 123, 115-123
DOI 10.1016/j.semcdb.2021.04.014, PubMed 33958284
Advances in immune therapies in hematological malignancies
J Intern Med, 292 (2), 205-220
DOI 10.1111/joim.13395, PubMed 34624160
The circulating soluble form of the CD40 costimulatory immune checkpoint receptor and liver metastasis risk in rectal cancer
Br J Cancer, 125 (2), 240-246
DOI 10.1038/s41416-021-01377-y, PubMed 33837301
Mcl-1 and Bcl-xL levels predict responsiveness to dual MEK/Bcl-2 inhibition in B-cell malignancies
Mol Oncol, 16 (5), 1153-1170
DOI 10.1002/1878-0261.13153, PubMed 34861096
"Built-in" PD-1 blocker to rescue NK-92 activity from PD-L1-mediated tumor escape mechanisms
FASEB J, 35 (9), e21750
DOI 10.1096/fj.202100025R, PubMed 34424568
Extended plasma half-life of albumin-binding domain fused human IgA upon pH-dependent albumin engagement of human FcRn in vitro and in vivo
MAbs, 13 (1), 1893888
DOI 10.1080/19420862.2021.1893888, PubMed 33691596
Integrating Serum Biomarkers into Prediction Models for Biochemical Recurrence Following Radical Prostatectomy
Cancers (Basel), 13 (16)
DOI 10.3390/cancers13164162, PubMed 34439316
De novo transcriptomic subtyping of colorectal cancer liver metastases in the context of tumor heterogeneity
Genome Med, 13 (1), 143
DOI 10.1186/s13073-021-00956-1, PubMed 34470666
Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment
Breast Cancer Res, 23 (1), 86
DOI 10.1186/s13058-021-01450-7, PubMed 34407845
GAK and PRKCD are positive regulators of PRKN-independent mitophagy
Nat Commun, 12 (1), 6101
DOI 10.1038/s41467-021-26331-7, PubMed 34671015
Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines
iScience, 24 (7), 102807
DOI 10.1016/j.isci.2021.102807, PubMed 34337362
Genetic variants associated with methotrexate-induced mucositis in cancer treatment: A systematic review and meta-analysis
Crit Rev Oncol Hematol, 161, 103312
DOI 10.1016/j.critrevonc.2021.103312, PubMed 33794308
The Quandary of DNA-Based Treatment Assessment in De Novo Metastatic Prostate Cancer in the Era of Precision Oncology
J Pers Med, 11 (5)
DOI 10.3390/jpm11050330, PubMed 33922147
Cancer Predisposition Sequencing Reporter (CPSR): A flexible variant report engine for high-throughput germline screening in cancer
Int J Cancer, 149 (11), 1955-1960
DOI 10.1002/ijc.33749, PubMed 34310709
Radon-220 diffusion from 224Ra-labeled calcium carbonate microparticles: Some implications for radiotherapeutic use
PLoS One, 16 (3), e0248133
DOI 10.1371/journal.pone.0248133, PubMed 33662039
An improved in vitro photochemical internalization protocol for 3D spheroid cultures
Lasers Med Sci, 36 (8), 1567-1571
DOI 10.1007/s10103-021-03332-y, PubMed 34185168
MicroRNA in combination with HER2-targeting drugs reduces breast cancer cell viability in vitro
Sci Rep, 11 (1), 10893
DOI 10.1038/s41598-021-90385-2, PubMed 34035375
Effects of a Unique Combination of the Whole-Body Low Dose Radiotherapy with Inactivation of Two Immune Checkpoints and/or a Heat Shock Protein on the Transplantable Lung Cancer in Mice
Int J Mol Sci, 22 (12)
DOI 10.3390/ijms22126309, PubMed 34208396
Immune checkpoint B7-H3 protein expression is associated with poor outcome and androgen receptor status in prostate cancer
Prostate, 81 (12), 838-848
DOI 10.1002/pros.24180, PubMed 34125445
Protein Tyrosine Phosphatases in Neuroblastoma: Emerging Roles as Biomarkers and Therapeutic Targets
Front Cell Dev Biol, 9, 811297
DOI 10.3389/fcell.2021.811297, PubMed 34957126
Karonudib has potent anti-tumor effects in preclinical models of B-cell lymphoma
Sci Rep, 11 (1), 6317
DOI 10.1038/s41598-021-85613-8, PubMed 33737576
Photochemical Internalization Enhanced Vaccination Is Safe, and Gives Promising Cellular Immune Responses to an HPV Peptide-Based Vaccine in a Phase I Clinical Study in Healthy Volunteers
Front Immunol, 11, 576756
DOI 10.3389/fimmu.2020.576756, PubMed 33488576
Biodistribution of Poly(alkyl cyanoacrylate) Nanoparticles in Mice and Effect on Tumor Infiltration of Macrophages into a Patient-Derived Breast Cancer Xenograft
Nanomaterials (Basel), 11 (5)
DOI 10.3390/nano11051140, PubMed 33924869
Gene-Environment Interactions Relevant to Estrogen and Risk of Breast Cancer: Can Gene-Environment Interactions Be Detected Only among Candidate SNPs from Genome-Wide Association Studies?
Cancers (Basel), 13 (10)
DOI 10.3390/cancers13102370, PubMed 34069208
The immuneML ecosystem for machine learning analysis of adaptive immune receptor repertoires
Nat Mach Intell, 3 (11), 936-944
DOI 10.1038/s42256-021-00413-z, PubMed 37396030
Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden
Nat Commun, 12 (1), 3230
DOI 10.1038/s41467-021-23445-w, PubMed 34050156
Identification of 22 susceptibility loci associated with testicular germ cell tumors
Nat Commun, 12 (1), 4487
DOI 10.1038/s41467-021-24334-y, PubMed 34301922
DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development
Atherosclerosis, 324, 123-132
DOI 10.1016/j.atherosclerosis.2021.02.023, PubMed 33714552
Proteomic analyses identify major vault protein as a prognostic biomarker for fatal prostate cancer
Carcinogenesis, 42 (5), 685-693
DOI 10.1093/carcin/bgab015, PubMed 33609362
Extracellular vesicles as a source of prostate cancer biomarkers in liquid biopsies: a decade of research
Br J Cancer, 126 (3), 331-350
DOI 10.1038/s41416-021-01610-8, PubMed 34811504
Potential of miRNAs in urinary extracellular vesicles for management of active surveillance in prostate cancer patients
Br J Cancer, 126 (3), 492-501
DOI 10.1038/s41416-021-01598-1, PubMed 34811506
The phosphatidylinositol 3-phosphate-binding protein SNX4 controls ATG9A recycling and autophagy
J Cell Sci, 134 (3)
DOI 10.1242/jcs.250670, PubMed 33468622
Rapid genome editing by CRISPR-Cas9-POLD3 fusion
Elife, 10
DOI 10.7554/eLife.75415, PubMed 34898428
Superior Graft-versus-Host Disease-Free Relapse-Free Survival in Matched Unrelated Donor Hematopoietic Stem Cell Transplantation with Anti-Thymocyte Globulin (ATG) Compared to Matched Related Donor without ATG
Transplant Cell Ther, 27 (7), 621.e1-621.e3
DOI 10.1016/j.jtct.2021.03.019, PubMed 33895156
Structural Analysis of Toxin-Neutralizing, Single-Domain Antibodies that Bridge Ricin's A-B Subunit Interface
J Mol Biol, 433 (15), 167086
DOI 10.1016/j.jmb.2021.167086, PubMed 34089718
mmsig: a fitting approach to accurately identify somatic mutational signatures in hematological malignancies
Commun Biol, 4 (1), 424
DOI 10.1038/s42003-021-01938-0, PubMed 33782531
Breast cancer metastasis: immune profiling of lymph nodes reveals exhaustion of effector T cells and immunosuppression
Mol Oncol, 16 (1), 88-103
DOI 10.1002/1878-0261.13047, PubMed 34165864
Differential Effects of Combined ATR/WEE1 Inhibition in Cancer Cells
Cancers (Basel), 13 (15)
DOI 10.3390/cancers13153790, PubMed 34359691
bayesynergy: flexible Bayesian modelling of synergistic interaction effects in in vitro drug combination experiments
Brief Bioinform, 22 (6)
DOI 10.1093/bib/bbab251, PubMed 34308471
The Protein Toxins Ricin and Shiga Toxin as Tools to Explore Cellular Mechanisms of Internalization and Intracellular Transport
Toxins (Basel), 13 (6)
DOI 10.3390/toxins13060377, PubMed 34070659
MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia
Cancer Res, 81 (22), 5733-5744
DOI 10.1158/0008-5472.CAN-21-0061, PubMed 34593524
The phosphoinositide coincidence detector Phafin2 promotes macropinocytosis by coordinating actin organisation at forming macropinosomes
Nat Commun, 12 (1), 6577
DOI 10.1038/s41467-021-26775-x, PubMed 34772942
ALK inhibition activates LC3B-independent, protective autophagy in EML4-ALK positive lung cancer cells
Sci Rep, 11 (1), 9011
DOI 10.1038/s41598-021-87966-6, PubMed 33907223
Uptake of hysterectomy and bilateral salpingo-oophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
Eur J Cancer, 148, 124-133
DOI 10.1016/j.ejca.2021.02.022, PubMed 33743481
European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender
Br J Surg, 108 (5), 484-498
DOI 10.1002/bjs.11902, PubMed 34043773
System-Wide Pollution of Biomedical Data: Consequence of the Search for Hub Genes of Hepatocellular Carcinoma Without Spatiotemporal Consideration
Mol Diagn Ther, 25 (1), 9-27
DOI 10.1007/s40291-020-00505-3, PubMed 33475988
Autophagy modulates cell fate decisions during lineage commitment
Autophagy, 18 (8), 1915-1931
DOI 10.1080/15548627.2021.2008691, PubMed 34923909
Novel Small Molecule Hsp90/Cdc37 Interface Inhibitors Indirectly Target K-Ras-Signaling
Cancers (Basel), 13 (4)
DOI 10.3390/cancers13040927, PubMed 33672199
Characterization of mechanisms positioning costimulatory complexes in immune synapses
iScience, 24 (10), 103100
DOI 10.1016/j.isci.2021.103100, PubMed 34622155
RNA Interference: Story and Mechanisms
Methods Mol Biol, 2282, 1-15
DOI 10.1007/978-1-0716-1298-9_1, PubMed 33928566
Evaluation of In Vitro Phototoxicity of a Minibody-IR700 Conjugate Using Cell Monolayer and Multicellular Tumor Spheroid Models
Cancers (Basel), 13 (13)
DOI 10.3390/cancers13133356, PubMed 34283089
Transport of nanoparticles across the endothelial cell layer
Nano Today, 36, 101029
DOI 10.1016/j.nantod.2020.101029
Overcoming resistance to targeted therapies in chronic lymphocytic leukemia
Blood Adv, 5 (1), 334-343
DOI 10.1182/bloodadvances.2020003423, PubMed 33570649
Treatment outcomes and prognostic factors after chemoradiotherapy for anal cancer
Acta Oncol, 60 (7), 921-930
DOI 10.1080/0284186X.2021.1918763, PubMed 33966592
Progress and challenges in mass spectrometry-based analysis of antibody repertoires
Trends Biotechnol, 40 (4), 463-481
DOI 10.1016/j.tibtech.2021.08.006, PubMed 34535228
Challenges to Bringing Personalized Medicine to a Low-Resource Setting in Peru
Int J Environ Res Public Health, 18 (4)
DOI 10.3390/ijerph18041470, PubMed 33557277
What It Takes to Transform a T Cell
Cancer Res, 81 (12), 3160-3161
DOI 10.1158/0008-5472.CAN-21-0784, PubMed 34224376
Methylation-dependent SUMOylation of the architectural transcription factor HMGA2
Biochem Biophys Res Commun, 552, 91-97
DOI 10.1016/j.bbrc.2021.02.099, PubMed 33744765
The landscape of tumor cell states and ecosystems in diffuse large B cell lymphoma
Cancer Cell, 39 (10), 1422-1437.e10
DOI 10.1016/j.ccell.2021.08.011, PubMed 34597589
Evaluation of the PSMA-Binding Ligand 212Pb-NG001 in Multicellular Tumour Spheroid and Mouse Models of Prostate Cancer
Int J Mol Sci, 22 (9)
DOI 10.3390/ijms22094815, PubMed 34062920
Breast cancer risk after age 60 among BRCA1 and BRCA2 mutation carriers
Breast Cancer Res Treat, 187 (2), 515-523
DOI 10.1007/s10549-020-06072-9, PubMed 33423179
Natural killer cell receptors regulate responses of HLA-E-restricted T cells
Sci Immunol, 6 (58)
DOI 10.1126/sciimmunol.abe9057, PubMed 33893172
The expressed mutational landscape of microsatellite stable colorectal cancers
Genome Med, 13 (1), 142
DOI 10.1186/s13073-021-00955-2, PubMed 34470667
Novel human melanoma brain metastasis models in athymic nude fox1nu mice: Site-specific metastasis patterns reflecting their clinical origin
Cancer Med, 10 (23), 8604-8613
DOI 10.1002/cam4.4334, PubMed 34612023
Negative Regulation of FGFR (Fibroblast Growth Factor Receptor) Signaling
Cells, 10 (6)
DOI 10.3390/cells10061342, PubMed 34071546
Perturbation of Cellular Redox Homeostasis Dictates Divergent Effects of Polybutyl Cyanoacrylate (PBCA) Nanoparticles on Autophagy
Cells, 10 (12)
DOI 10.3390/cells10123432, PubMed 34943939
Trafficking of Full-Length and N-Terminally Truncated Cathepsin B in Human Colorectal Carcinoma Cells
Appl. Sci.-Basel, 11 (24), 11936
DOI 10.3390/app112411936
JIP4 is recruited by the phosphoinositide-binding protein Phafin2 to promote recycling tubules on macropinosomes
J Cell Sci, 134 (14)
DOI 10.1242/jcs.258495, PubMed 34109410
Artificial intelligence, machine learning, and drug repurposing in cancer
Expert Opin Drug Discov, 16 (9), 977-989
DOI 10.1080/17460441.2021.1883585, PubMed 33543671
High-throughput proteomics of breast cancer interstitial fluid: identification of tumor subtype-specific serologically relevant biomarkers
Mol Oncol, 15 (2), 429-461
DOI 10.1002/1878-0261.12850, PubMed 33176066
Increased Local Inflammatory Response to MOC31PE Immunotoxin After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
Ann Surg Oncol, 28 (9), 5252-5262
DOI 10.1245/s10434-021-10022-0, PubMed 34019185
MMADHC premature termination codons in the pathogenesis of cobalamin D disorder: Potential of translational readthrough reconstitution
Mol Genet Metab Rep, 26, 100710
DOI 10.1016/j.ymgmr.2021.100710, PubMed 33552904
Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T-Cell Prolymphocytic Leukemia
J Med Chem, 64 (12), 8486-8509
DOI 10.1021/acs.jmedchem.1c00420, PubMed 34101461
Long-term first-in-man Phase I/II study of an adjuvant dendritic cell vaccine in patients with high-risk prostate cancer after radical prostatectomy
Prostate, 82 (2), 245-253
DOI 10.1002/pros.24267, PubMed 34762317
Amino acid transporter expression and 18F-FACBC uptake at PET in primary prostate cancer
Am J Nucl Med Mol Imaging, 11 (4), 250-259
PubMed 34513278
Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse
Nat Commun, 12 (1), 5307
DOI 10.1038/s41467-021-25624-1, PubMed 34489465
Adaptation to hypoxia in Drosophila melanogaster requires autophagy
Autophagy, 18 (4), 909-920
DOI 10.1080/15548627.2021.1991191, PubMed 34793268
Mechanism of cellular uptake and cytotoxicity of paclitaxel loaded lipid nanocapsules in breast cancer cells
Int J Pharm, 597, 120217
DOI 10.1016/j.ijpharm.2021.120217, PubMed 33486035
Benefit-Risk Assessment of Off-Label Drug Use in Children: The Bravo Framework
Clin Pharmacol Ther, 110 (4), 952-965
DOI 10.1002/cpt.2336, PubMed 34145575
Early and accurate detection of cholangiocarcinoma in patients with primary sclerosing cholangitis by methylation markers in bile
Hepatology, 75 (1), 59-73
DOI 10.1002/hep.32125, PubMed 34435693
Efficacy and Selectivity of FGF2-Saporin Cytosolically Delivered by PCI in Cells Overexpressing FGFR1
Cells, 10 (6)
DOI 10.3390/cells10061476, PubMed 34204611
The Prognostic Effect of KRAS Mutations in Non-Small Cell Lung Carcinoma Revisited: A Norwegian Multicentre Study
Cancers (Basel), 13 (17)
DOI 10.3390/cancers13174294, PubMed 34503114
In silico investigations of intratumoral heterogeneous interstitial fluid pressure
J Theor Biol, 526, 110787
DOI 10.1016/j.jtbi.2021.110787, PubMed 34087266
AKIP1 promotes tumor progression by cancer-related pathways and predicts prognosis in tongue squamous cell carcinoma
Am J Transl Res, 13 (11), 12338-12351
PubMed 34956456
Modeling drug combination effects via latent tensor reconstruction
Bioinformatics, 37 (Suppl_1), i93-i101
DOI 10.1093/bioinformatics/btab308, PubMed 34252952
Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition
Cell Rep, 35 (13), 109291
DOI 10.1016/j.celrep.2021.109291, PubMed 34192548
Inhibiting autophagy increases the efficacy of low-dose photodynamic therapy
Biochem Pharmacol, 194, 114837
DOI 10.1016/j.bcp.2021.114837, PubMed 34780750
Bayesian multi-source regression and monocyte-associated gene expression predict BCL-2 inhibitor resistance in acute myeloid leukemia
NPJ Precis Oncol, 5 (1), 71
DOI 10.1038/s41698-021-00209-9, PubMed 34302041
Drug Combinations as a First Line of Defense against Coronaviruses and Other Emerging Viruses
mBio, 12 (6), e0334721
DOI 10.1128/mbio.03347-21, PubMed 34933447
Drug Combinations as a First Line of Defense against Coronaviruses and Other Emerging Viruses
mBio, 12 (6), e03347-21
Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity
J Mol Biol, 433 (13), 166987
DOI 10.1016/j.jmb.2021.166987, PubMed 33845085
Harnessing features of adaptive NK cells to generate iPSC-derived NK cells for enhanced immunotherapy
Cell Stem Cell, 28 (12), 2062-2075.e5
DOI 10.1016/j.stem.2021.08.013, PubMed 34525347
Light-controlled elimination of PD-L1+ cells
J Photochem Photobiol B, 225, 112355
DOI 10.1016/j.jphotobiol.2021.112355, PubMed 34768077
Multi-Omics Marker Analysis Enables Early Prediction of Breast Tumor Progression
Front Genet, 12, 670749
DOI 10.3389/fgene.2021.670749, PubMed 34149812
The GAS6-AXL signaling pathway triggers actin remodeling that drives membrane ruffling, macropinocytosis, and cancer-cell invasion
Proc Natl Acad Sci U S A, 118 (28)
DOI 10.1073/pnas.2024596118, PubMed 34244439
Sealing holes in cellular membranes
EMBO J, 40 (7), e106922
DOI 10.15252/embj.2020106922, PubMed 33644904
Dynamic changes in the T cell receptor repertoire during treatment with radiotherapy combined with an immune checkpoint inhibitor
Mol Oncol, 15 (11), 2958-2968
DOI 10.1002/1878-0261.13082, PubMed 34402187
Cabazitaxel-loaded poly(alkyl cyanoacrylate) nanoparticles: toxicity and changes in the proteome of breast, colon and prostate cancer cells
Nanotoxicology, 15 (7), 865-884
DOI 10.1080/17435390.2021.1924888, PubMed 34047629
Combining a Universal Telomerase Based Cancer Vaccine With Ipilimumab in Patients With Metastatic Melanoma - Five-Year Follow Up of a Phase I/IIa Trial
Front Immunol, 12, 663865
DOI 10.3389/fimmu.2021.663865, PubMed 34046035
Ipilimumab in a real-world population: A prospective Phase IV trial with long-term follow-up
Int J Cancer, 150 (1), 100-111
DOI 10.1002/ijc.33768, PubMed 34449877
Prognostic role of tumour-infiltrating lymphocytes and macrophages in relation to MSI, CDX2 and BRAF status: a population-based study of metastatic colorectal cancer patients
Br J Cancer, 126 (1), 48-56
DOI 10.1038/s41416-021-01586-5, PubMed 34671130