Publications (original articles or review articles) published in 2024 from OUS - Institute for Cancer Research
57 publications found
Integrated drug profiling and CRISPR screening identify BCR::ABL1-independent vulnerabilities in chronic myeloid leukemia
Cell Rep Med, 101521 (in press)
DOI 10.1016/j.xcrm.2024.101521, PubMed 38653245
Machine Learning Made Easy (MLme): a comprehensive toolkit for machine learning-driven data analysis
Gigascience, 13
DOI 10.1093/gigascience/giad111, PubMed 38206587
Ipilimumab and nivolumab combined with anthracycline-based chemotherapy in metastatic hormone receptor-positive breast cancer: a randomized phase 2b trial
J Immunother Cancer, 12 (1)
DOI 10.1136/jitc-2023-007990, PubMed 38242720
Multi-omics analysis reveals epigenetically regulated processes and patient classification in lung adenocarcinoma
Int J Cancer (in press)
DOI 10.1002/ijc.34915, PubMed 38489486
Bi-allelic variants in SNF8 cause a disease spectrum ranging from severe developmental and epileptic encephalopathy to syndromic optic atrophy
Am J Hum Genet, 111 (3), 594-613
DOI 10.1016/j.ajhg.2024.02.005, PubMed 38423010
Efficient CAR T cell targeting of the CA125 extracellular repeat domain of MUC16
J Immunother Cancer, 12 (4)
DOI 10.1136/jitc-2023-008179, PubMed 38604812
Link between circadian rhythm and benign prostatic hyperplasia (BPH)/lower urinary tract symptoms (LUTS)
Prostate, 84 (5), 417-425
DOI 10.1002/pros.24656, PubMed 38193363
Peripheral immune cells in metastatic breast cancer patients display a systemic immunosuppressed signature consistent with chronic inflammation
NPJ Breast Cancer, 10 (1), 30
DOI 10.1038/s41523-024-00638-2, PubMed 38653982
Impact of Rare Structural Variant Events in Newly Diagnosed Multiple Myeloma
Clin Cancer Res, 30 (3), 575-585
DOI 10.1158/1078-0432.CCR-23-1045, PubMed 37939148
Characterization of a selective, iron-chelating antifungal compound that disrupts fungal metabolism and synergizes with fluconazole
Microbiol Spectr, 12 (2), e0259423
DOI 10.1128/spectrum.02594-23, PubMed 38230926
Ciliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubules
Science, 384 (6694), eadf5489
DOI 10.1126/science.adf5489, PubMed 38662826
Evaluation of NTRK expression and fusions in a large cohort of early-stage lung cancer
Clin Exp Med, 24 (1), 10
DOI 10.1007/s10238-023-01273-0, PubMed 38240952
Discovery and technical validation of high-performance methylated DNA markers for the detection of cervical lesions at risk of malignant progression in low- and middle-income countries
Clin Epigenetics, 16 (1), 56
DOI 10.1186/s13148-024-01669-z, PubMed 38643219
The impact of level of documentation on the accessibility and affordability of new drugs in Norway
Front Pharmacol, 15, 1338541
DOI 10.3389/fphar.2024.1338541, PubMed 38420198
Systematic evaluation of donor-KIR/recipient-HLA interactions in HLA-matched hematopoietic cell transplantation for AML
Blood Adv, 8 (3), 581-590
DOI 10.1182/bloodadvances.2023011622, PubMed 38052043
Incidence and Factors Associated With Second Primary Invasive Melanoma in Norway
JAMA Dermatol, 160 (4), 402-408
DOI 10.1001/jamadermatol.2023.6251, PubMed 38416466
ALDH1A1 drives prostate cancer metastases and radioresistance by interplay with AR- and RAR-dependent transcription
Theranostics, 14 (2), 714-737
DOI 10.7150/thno.88057, PubMed 38169509
T cells with increased responsiveness cause obesity in mice without diet intervention
iScience, 27 (4), 109471
DOI 10.1016/j.isci.2024.109471, PubMed 38551005
Outcomes of 10 years of PSA screening for prostate cancer in Norwegian men with Lynch syndrome
Prostate (in press)
DOI 10.1002/pros.24711, PubMed 38629217
Systemic interrogation of immune-oncology-related proteins in patients with locally advanced prostate cancer undergoing androgen deprivation and intensity-modulated radiotherapy
World J Urol, 42 (1), 95
DOI 10.1007/s00345-024-04787-8, PubMed 38386171
Lung cancer reirradiation: Exploring modifications to utilization, treatment modalities and factors associated with outcomes
J Med Imaging Radiat Sci (in press)
DOI 10.1016/j.jmir.2024.02.004, PubMed 38429174
Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity
Nat Immunol (in press)
DOI 10.1038/s41590-024-01802-3, PubMed 38561495
Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial
Nat Med, 30 (2), 498-506
DOI 10.1038/s41591-023-02734-5, PubMed 38182785
[Not Available]
Tidsskr Nor Laegeforen, 144 (1)
DOI 10.4045/tidsskr.23.0740, PubMed 38258713
Chronic fatigue in long-term survivors of head and neck cancer treated with radiotherapy
Radiother Oncol, 195, 110231 (in press)
DOI 10.1016/j.radonc.2024.110231, PubMed 38518958
UV1 telomerase vaccine with ipilimumab and nivolumab as second line treatment for pleural mesothelioma - A phase II randomised trial
Eur J Cancer, 202, 113973
DOI 10.1016/j.ejca.2024.113973, PubMed 38447379
Exploring the gut DNA virome in fecal immunochemical test stool samples reveals associations with lifestyle in a large population-based study
Nat Commun, 15 (1), 1791
DOI 10.1038/s41467-024-46033-0, PubMed 38424056
Comparative Evaluation of STEAP1 Targeting Chimeric Antigen Receptors with Different Costimulatory Domains and Spacers
Int J Mol Sci, 25 (1)
DOI 10.3390/ijms25010586, PubMed 38203757
The dual role of autophagy in HPV-positive head and neck squamous cell carcinoma: a systematic review
J Cancer Res Clin Oncol, 150 (2), 56
DOI 10.1007/s00432-023-05514-3, PubMed 38291202
Clathrin controls bidirectional communication between T cells and antigen presenting cells
Bioessays, 46 (4), e2300230
DOI 10.1002/bies.202300230, PubMed 38412391
An Immune Gene Expression Risk Score for Distant Metastases after Radiotherapy for Cervical Cancer
Clin Cancer Res, 30 (6), 1200-1207
DOI 10.1158/1078-0432.CCR-23-2085, PubMed 38180733
A federated learning system for precision oncology in Europe: DigiONE
Nat Med, 30 (2), 334-337
DOI 10.1038/s41591-023-02715-8, PubMed 38195748
The prognostic effect of tumor-associated macrophages in stage I-III colorectal cancer depends on T cell infiltration
Cell Oncol (Dordr) (in press)
DOI 10.1007/s13402-024-00926-w, PubMed 38407700
Engineering immune-evasive allogeneic cellular immunotherapies
Nat Rev Immunol (in press)
DOI 10.1038/s41577-024-01022-8, PubMed 38658708
Disruption of KLHL6 Fuels Oncogenic Antigen Receptor Signaling in B-cell Lymphoma
Blood Cancer Discov (in press)
DOI 10.1158/2643-3230.BCD-23-0182, PubMed 38630892
Gender Difference in sidE eFfects of ImmuNotherapy: a possible clue to optimize cancEr tReatment (G-DEFINER): study protocol of an observational prospective multicenter study
Acta Oncol, 63, 213-219
DOI 10.2340/1651-226X.2024.24179, PubMed 38647024
Kinase-impaired BTK mutations are susceptible to clinical-stage BTK and IKZF1/3 degrader NX-2127
Science, 383 (6682), eadi5798
DOI 10.1126/science.adi5798, PubMed 38301010
Roadmap for a European cancer data management and precision medicine infrastructure
Nat Cancer, 5 (3), 367-372
DOI 10.1038/s43018-023-00717-6, PubMed 38321342
Experiences and challenges with the new European Clinical Trials Regulation
Trials, 25 (1), 3
DOI 10.1186/s13063-023-07869-x, PubMed 38167484
Transmembrane domain-driven PD-1 dimers mediate T cell inhibition
Sci Immunol, 9 (93), eade6256
DOI 10.1126/sciimmunol.ade6256, PubMed 38457513
JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles
Nucleic Acids Res, 52 (D1), D174-D182
DOI 10.1093/nar/gkad1059, PubMed 37962376
First-line oxaliplatin-based chemotherapy and nivolumab for metastatic microsatellite-stable colorectal cancer-the randomised METIMMOX trial
Br J Cancer (in press)
DOI 10.1038/s41416-024-02696-6, PubMed 38664577
Strategies to decrease inequalities in cancer therapeutics, care and prevention: Proceedings on a conference organized by the Pontifical Academy of Sciences and the European Academy of Cancer Sciences, Vatican City, February 23-24, 2023
Mol Oncol, 18 (2), 245-279
DOI 10.1002/1878-0261.13575, PubMed 38135904
MRI-guided dynamic risk assessment in cervical cancer based on tumor hypoxia at diagnosis and volume response at brachytherapy
Radiother Oncol, 195, 110263 (in press)
DOI 10.1016/j.radonc.2024.110263, PubMed 38556173
Prostate cancer: Molecular aspects, consequences, and opportunities of the multifocal nature
Biochim Biophys Acta Rev Cancer, 1879 (2), 189080
DOI 10.1016/j.bbcan.2024.189080, PubMed 38272101
Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia
J Clin Invest, 134 (8)
DOI 10.1172/JCI168536, PubMed 38618957
Evolutionary mode and timing of dissemination of high-grade serous carcinomas
JCI Insight, 9 (3)
DOI 10.1172/jci.insight.170423, PubMed 38175731
Induction of Translational Readthrough on Protein Tyrosine Phosphatases Targeted by Premature Termination Codon Mutations in Human Disease
Methods Mol Biol, 2743, 1-19
DOI 10.1007/978-1-0716-3569-8_1, PubMed 38147205
The E3 ubiquitin ligase ITCH negatively regulates intercellular communication via gap junctions by targeting connexin43 for lysosomal degradation
Cell Mol Life Sci, 81 (1), 171
DOI 10.1007/s00018-024-05165-8, PubMed 38597989
Preclinical Efficacy of Cabazitaxel Loaded Poly(2-alkyl cyanoacrylate) Nanoparticle Variants
Int J Nanomedicine, 19, 3009-3029
DOI 10.2147/IJN.S450283, PubMed 38562610
A TEMPORAL DEVELOPMENTAL MAP SEPARATES HUMAN NK CELLS FROM NON-CYTOTOXIC ILCS THROUGH CLONAL AND SINGLE-CELL ANALYSIS
Blood Adv (in press)
DOI 10.1182/bloodadvances.2023011909, PubMed 38484189
Meeting Summary of The NYO3 5th NO-Age/AD Meeting and the 1st Norway-UK Joint Meeting on Aging and Dementia: Recent Progress on the Mechanisms and Interventional Strategies
J Gerontol A Biol Sci Med Sci, 79 (4)
DOI 10.1093/gerona/glae029, PubMed 38289789
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
J Extracell Vesicles, 13 (2), e12404
DOI 10.1002/jev2.12404, PubMed 38326288
Intercellular transfer of cancer cell invasiveness via endosome-mediated protease shedding
Nat Commun, 15 (1), 1277
DOI 10.1038/s41467-024-45558-8, PubMed 38341434
Using birth-death processes to infer tumor subpopulation structure from live-cell imaging drug screening data
PLoS Comput Biol, 20 (3), e1011888
DOI 10.1371/journal.pcbi.1011888, PubMed 38446830
Tutorial on survival modeling with applications to omics data
Bioinformatics, 40 (3)
DOI 10.1093/bioinformatics/btae132, PubMed 38445722
Systematic analysis of RNA-binding proteins identifies targetable therapeutic vulnerabilities in osteosarcoma
Nat Commun, 15 (1), 2810
DOI 10.1038/s41467-024-47031-y, PubMed 38561347