RSS feed

Publications (original articles or review articles) published in 2024 from OUS - Department of Tumor Biology

41 publications found

Akdeniz BC, Frei O, Hagen E, Filiz TT, Karthikeyan S, Pasman J, Jangmo A, Bergstedt J, Shorter JR, Zetterberg R, Meijsen J, Sønderby IE, Buil A, Tesli M, Lu Y, Sullivan P, Andreassen OA, Hovig E (2024)
COSGAP: COntainerized Statistical Genetics Analysis Pipelines
Bioinform Adv, 4 (1), vbae067
DOI 10.1093/bioadv/vbae067, PubMed 38808072

Akdeniz BC, Frei O, Shadrin A, Vetrov D, Kropotov D, Hovig E, Andreassen OA, Dale AM (2024)
Finemap-MiXeR: A variational Bayesian approach for genetic finemapping
PLoS Genet, 20 (8), e1011372
DOI 10.1371/journal.pgen.1011372, PubMed 39146375

Angulo JC, Larrinaga G, Lecumberri D, Iturregui AM, Solano-Iturri JD, Lawrie CH, Armesto M, Dorado JF, Nunes-Xavier CE, Pulido R, Manini C, López JI (2024)
Predicting Survival of Metastatic Clear Cell Renal Cell Cancer Treated with VEGFR-TKI-Based Sequential Therapy
Cancers (Basel), 16 (16)
DOI 10.3390/cancers16162786, PubMed 39199559

Bai B, Wise JF, Vodák D, Nakken S, Sharma A, Blaker YN, Brodtkorb M, Hilden V, Trøen G, Ren W, Lorenz S, Lawrence MS, Myklebost O, Kimby E, Pan-Hammarström Q, Steen CB, Meza-Zepeda LA, Beiske K, Smeland EB, Hovig E, Lingjærde OC, Holte H, Myklebust JH (2024)
Multi-omics profiling of longitudinal samples reveals early genomic changes in follicular lymphoma
Blood Cancer J, 14 (1), 147
DOI 10.1038/s41408-024-01124-5, PubMed 39191762

Bischof K, Cremaschi A, Eroukhmanoff L, Landskron J, Flage-Larsen LL, Gade A, Bjørge L, Urbanucci A, Taskén K (2024)
Patient-derived acellular ascites fluid affects drug responses in ovarian cancer cell lines through the activation of key signalling pathways
Mol Oncol (in press)
DOI 10.1002/1878-0261.13726, PubMed 39245677

Bucher-Johannessen C, Senthakumaran T, Avershina E, Birkeland E, Hoff G, Bemanian V, Tunsjø H, Rounge TB (2024)
Species-level verification of Phascolarctobacterium association with colorectal cancer
mSystems, e0073424 (in press)
DOI 10.1128/msystems.00734-24, PubMed 39287376

Cavanaugh D, Urbanucci A, Mohamed NE, Tewari AK, Figueiro M, Kyprianou N (2024)
Link between circadian rhythm and benign prostatic hyperplasia (BPH)/lower urinary tract symptoms (LUTS)
Prostate, 84 (5), 417-425
DOI 10.1002/pros.24656, PubMed 38193363

Dagenborg VJ, Brudvik KW, Lund-Andersen C, Torgunrud A, Lund-Iversen M, Flatmark K, Larsen SG, Yaqub S (2024)
Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy and Liver Resection is a Treatment Option for Patients With Peritoneal and Liver Metastases From Colorectal Cancer
Ann Surg, 280 (5), 745-52 (in press)
DOI 10.1097/SLA.0000000000006492, PubMed 39185557

Davidson B, Holth A, Lindemann K, Zahl Eriksson AG, Nilsen TA, Torgunrud A (2024)
Molecular characteristics of tubo-ovarian carcinosarcoma at different anatomic locations
Virchows Arch (in press)
DOI 10.1007/s00428-024-03821-9, PubMed 38733380

Edsjö A, Russnes HG, Lehtiö J, Tamborero D, Hovig E, Stenzinger A, Rosenquist R, PCM4EU consortium (2024)
High-throughput molecular assays for inclusion in personalised oncology trials - State-of-the-art and beyond
J Intern Med, 295 (6), 785-803
DOI 10.1111/joim.13785, PubMed 38698538

Egeland EV, Seip K, Skourti E, Øy GF, Pettersen SJ, Pandya AD, Dahle MA, Haugen MH, Kristian A, Nakken S, Engebraaten O, Mælandsmo GM, Prasmickaite L (2024)
The SRC-family serves as a therapeutic target in triple negative breast cancer with acquired resistance to chemotherapy
Br J Cancer (in press)
DOI 10.1038/s41416-024-02875-5, PubMed 39390250

Emaldi M, Alamillo-Maeso P, Rey-Iborra E, Mosteiro L, Lecumberri D, Pulido R, López JI, Nunes-Xavier CE (2024)
A functional role for glycosylated B7-H5/VISTA immune checkpoint protein in metastatic clear cell renal cell carcinoma
iScience, 27 (9), 110587
DOI 10.1016/j.isci.2024.110587, PubMed 39262813

Esperon P, Neffa F, Pavicic W, Spirandelli F, Alvarez K, Mullins MJ, Rossi BM, Góngora E Silva RF, Vaccaro C, Lopéz-Köstner F, Rugeles J, Valle AD, Dominguez-Valentin M (2024)
A comprehensive characterization of the spectrum of MUTYH germline pathogenic variants in Latin America
Fam Cancer (in press)
DOI 10.1007/s10689-024-00382-3, PubMed 38687439

Fleischer T, Haugen MH, Ankill J, Silwal-Pandit L, Børresen-Dale AL, Hedenfalk I, Hatschek T, Tost J, Engebraaten O, Kristensen VN (2024)
An integrated omics approach highlights how epigenetic events can explain and predict response to neoadjuvant chemotherapy and bevacizumab in breast cancer
Mol Oncol, 18 (8), 2042-2059
DOI 10.1002/1878-0261.13656, PubMed 38671580

Foote JB, Mattox TE, Keeton AB, Chen X, Smith F, Berry KL, Holmes T, Wang J, Huang CH, Ward AB, Mitra AK, Ramirez-Alcantara V, Hardy C, Fleten KG, Flatmark K, Yoon KJ, Sarvesh S, Nagaraju GP, Maxuitenko Y, Valiyaveettil J, Carstens JL, Buchsbaum DJ, Yang J, Zhou G, Nurmemmedov E et al. (2024)
A Novel Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth in Mouse Models of GI Cancer
bioRxiv
DOI 10.1101/2023.05.17.541233, PubMed 38328254

Guldvik IJ, Ramberg H, Kristensen G, Røder A, Mills IG, Lilleby W, Taskén KA (2024)
Systemic interrogation of immune-oncology-related proteins in patients with locally advanced prostate cancer undergoing androgen deprivation and intensity-modulated radiotherapy
World J Urol, 42 (1), 95
DOI 10.1007/s00345-024-04787-8, PubMed 38386171

Heinrich MC, Jones RL, George S, Gelderblom H, Schöffski P, von Mehren M, Zalcberg JR, Kang YK, Razak AA, Trent J, Attia S, Le Cesne A, Siontis BL, Goldstein D, Boye K, Sanchez C, Steeghs N, Rutkowski P, Druta M, Serrano C, Somaiah N, Chi P, Reichmann W, Sprott K, Achour H et al. (2024)
Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial
Nat Med, 30 (2), 498-506
DOI 10.1038/s41591-023-02734-5, PubMed 38182785

Istvan P, Birkeland E, Avershina E, Kværner AS, Bemanian V, Pardini B, Tarallo S, de Vos WM, Rognes T, Berstad P, Rounge TB (2024)
Exploring the gut DNA virome in fecal immunochemical test stool samples reveals associations with lifestyle in a large population-based study
Nat Commun, 15 (1), 1791
DOI 10.1038/s41467-024-46033-0, PubMed 38424056

Kandathil SA, Akhondi A, Kadletz-Wanke L, Heiduschka G, Engedal N, Brkic FF (2024)
The dual role of autophagy in HPV-positive head and neck squamous cell carcinoma: a systematic review
J Cancer Res Clin Oncol, 150 (2), 56
DOI 10.1007/s00432-023-05514-3, PubMed 38291202

Kotsopoulos J, Lubinski J, Huzarski T, Bychkovsky BL, Moller P, Kim RH, Tung N, Eisen A, Foulkes W, Singer CF, Aeilts A, Neuhausen SL, Bordeleau L, Karlan B, Fruscio R, Eng C, Olopade O, Zakalik D, Couch F, Y Cajal TR, Sun P, Gronwald J, Narod SA (2024)
Incidence of endometrial cancer in BRCA mutation carriers
Gynecol Oncol, 189, 148-155
DOI 10.1016/j.ygyno.2024.07.687, PubMed 39173195

Kurganovs NJ, Engedal N (2024)
To eat or not to eat: a critical review on the role of autophagy in prostate carcinogenesis and prostate cancer therapeutics
Front Pharmacol, 15, 1419806
DOI 10.3389/fphar.2024.1419806, PubMed 38910881

Lamsal A, Andersen SB, Johansson I, Desgarnier MD, Wolowczyk C, Engedal N, Vietri M, Bjørkøy G, Giambelluca MS, Pettersen K (2024)
Elucidating the power of arginine restriction: taming type I interferon response in breast cancer via selective autophagy
Cell Commun Signal, 22 (1), 481
DOI 10.1186/s12964-024-01858-6, PubMed 39380098

Lund-Andersen C, Torgunrud A, Kanduri C, Dagenborg VJ, Frøysnes IS, Larsen MM, Davidson B, Larsen SG, Flatmark K (2024)
Novel drug resistance mechanisms and drug targets in BRAF-mutated peritoneal metastasis from colorectal cancer
J Transl Med, 22 (1), 646
DOI 10.1186/s12967-024-05467-2, PubMed 38982444

Mattavelli D, Wichmann G, Smussi D, Paderno A, Plana MS, Mesia RN, Compagnoni M, Medda A, Chiocca S, Calza S, Zhan Y, Rognoni C, Tarricone R, Stucchi E, Lorini L, Gurizzan C, Khelik K, Hovig E, Dietz A, Piazza C, Bossi P (2024)
Is precision medicine the solution to improve organ preservation in laryngeal/hypopharyngeal cancer? A position paper by the Preserve Research Group
Front Oncol, 14, 1433333
DOI 10.3389/fonc.2024.1433333, PubMed 39165689

Møller P, Haupt S, Ahadova A, Kloor M, Sampson JR, Sunde L, Seppälä T, Burn J, Bernstein I, Capella G, Evans DG, Lindblom A, Winship I, Macrae F, Katz L, Laish I, Vainer E, Monahan K, Half E, Horisberger K, da Silva LA, Heuveline V, Therkildsen C, Lautrup C, Klarskov LL et al. (2024)
Incidences of colorectal adenomas and cancers under colonoscopy surveillance suggest an accelerated "Big Bang" pathway to CRC in three of the four Lynch syndromes
Hered Cancer Clin Pract, 22 (1), 6
DOI 10.1186/s13053-024-00279-3, PubMed 38741120

Møller P, Seppälä TT, Domiguez-Valentin M, Sampson J (2024)
Commentary on Estimating cancer risk in carriers of Lynch syndrome variants in UK Biobank
J Med Genet (in press)
DOI 10.1136/jmg-2024-110385, PubMed 39375027

Narod SA, Gronwald J, Karlan B, Moller P, Huzarski T, Tung N, Aeilts A, Eisen A, Randall Armel S, Singer CF, Foulkes WD, Neuhausen SL, Olopade O, Pal T, Fruscio R, Metcalfe K, Raj R, Jacobson M, Sun P, Lubinski J, Kotsopoulos J (2024)
Incidence of Peritoneal Cancer Following Oophorectomy among BRCA1 and BRCA2 Mutation Carriers
J Natl Cancer Inst (in press)
DOI 10.1093/jnci/djae151, PubMed 38937272

Nikolski M, Hovig E, Al-Shahrour F, Blomberg N, Scollen S, Valencia A, Saunders G (2024)
Roadmap for a European cancer data management and precision medicine infrastructure
Nat Cancer, 5 (3), 367-372
DOI 10.1038/s43018-023-00717-6, PubMed 38321342

Patrick-Brown TDJH, Bourner J, Kali S, Trøseid M, Yazdanpanah Y, Olliaro P, Olsen IC (2024)
Experiences and challenges with the new European Clinical Trials Regulation
Trials, 25 (1), 3
DOI 10.1186/s13063-023-07869-x, PubMed 38167484

Pulido R, López JI, Nunes-Xavier CE (2024)
B7-H3: a robust target for immunotherapy in prostate cancer
Trends Cancer, 10 (7), 584-587
DOI 10.1016/j.trecan.2024.05.003, PubMed 38839545

Ranji P, Jonasson E, Andersson L, Filges S, Luna Santamaría M, Vannas C, Dolatabadi S, Gustafsson A, Myklebost O, Håkansson J, Fagman H, Landberg G, Åman P, Ståhlberg A (2024)
Deciphering the role of FUS::DDIT3 expression and tumor microenvironment in myxoid liposarcoma development
J Transl Med, 22 (1), 389
DOI 10.1186/s12967-024-05211-w, PubMed 38671504

Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Chèneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A (2024)
JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles
Nucleic Acids Res, 52 (D1), D174-D182
DOI 10.1093/nar/gkad1059, PubMed 37962376

Ree AH, Høye E, Esbensen Y, Beitnes AR, Negård A, Bernklev L, Tetlie LK, Fretland ÅA, Hamre HM, Kersten C, Hofsli E, Guren MG, Sorbye H, Nilsen HL, Flatmark K, Meltzer S (2024)
Complete response of metastatic microsatellite-stable BRAF V600E colorectal cancer to first-line oxaliplatin-based chemotherapy and immune checkpoint blockade
Oncoimmunology, 13 (1), 2372886
DOI 10.1080/2162402X.2024.2372886, PubMed 38952672

Ree AH, Šaltytė Benth J, Hamre HM, Kersten C, Hofsli E, Guren MG, Sorbye H, Johansen C, Negård A, Bjørnetrø T, Nilsen HL, Berg JP, Flatmark K, Meltzer S (2024)
First-line oxaliplatin-based chemotherapy and nivolumab for metastatic microsatellite-stable colorectal cancer-the randomised METIMMOX trial
Br J Cancer, 130 (12), 1921-1928
DOI 10.1038/s41416-024-02696-6, PubMed 38664577

Reppe S, Gundersen S, Sandve GK, Wang Y, Andreassen OA, Medina-Gomez C, Rivadeneira F, Utheim TP, Hovig E, Gautvik KM (2024)
Identification of Transcripts with Shared Roles in the Pathogenesis of Postmenopausal Osteoporosis and Cardiovascular Disease
Int J Mol Sci, 25 (10)
DOI 10.3390/ijms25105554, PubMed 38791593

Sveen A, Johannessen B, Klokkerud SM, Kraggerud SM, Meza-Zepeda LA, Bjørnslett M, Bischof K, Myklebost O, Taskén K, Skotheim RI, Dørum A, Davidson B, Lothe RA (2024)
Evolutionary mode and timing of dissemination of high-grade serous carcinomas
JCI Insight, 9 (3)
DOI 10.1172/jci.insight.170423, PubMed 38175731

Torices L, Nunes-Xavier CE, Mingo J, Luna S, Erramuzpe A, Cortés JM, Pulido R (2024)
Induction of Translational Readthrough on Protein Tyrosine Phosphatases Targeted by Premature Termination Codon Mutations in Human Disease
Methods Mol Biol, 2743, 1-19
DOI 10.1007/978-1-0716-3569-8_1, PubMed 38147205

Torices L, Nunes-Xavier CE, Pulido R (2024)
Potentiation by Protein Synthesis Inducers of Translational Readthrough of Pathogenic Premature Termination Codons in PTEN Isoforms
Cancers (Basel), 16 (16)
DOI 10.3390/cancers16162836, PubMed 39199607

Valsalakumari R, Pandya AD, Prasmickaite L, Kvalvaag A, Myrann AG, Åslund AKO, Kjos MS, Fontecha-Cuenca C, Haroon HB, Ribeiro ARS, Horejs-Hoeck J, Moghimi SM, Mørch Ý, Skotland T, Sandvig K, Mælandsmo GM, Iversen TG (2024)
Preclinical Efficacy of Cabazitaxel Loaded Poly(2-alkyl cyanoacrylate) Nanoparticle Variants
Int J Nanomedicine, 19, 3009-3029
DOI 10.2147/IJN.S450283, PubMed 38562610

van der Werf-'t Lam AS, Rodriguez-Girondo M, Villasmil M, Tops CM, van Hest L, Gille HJP, Duijkers FAM, Wagner A, Eikenboom E, Letteboer TGW, de Jong MM, Bajwa-Ten Broeke SW, Bleeker F, Gomez Garcia EB, Dominguez-Valentin M, Møller P, Suerink M, Nielsen M (2024)
Delineating genotype and parent-of-origin effect on the phenotype in MSH6-associated Lynch syndrome
Genes Chromosomes Cancer, 63 (5), e23237
DOI 10.1002/gcc.23237, PubMed 38722212

Zhou Y, Ray PS, Zhu J, Stein F, Rettel M, Sekaran T, Sahadevan S, Perez-Perri JI, Roth EK, Myklebost O, Meza-Zepeda LA, von Deimling A, Fu C, Brosig AN, Boye K, Nathrath M, Blattmann C, Lehner B, Hentze MW, Kulozik AE (2024)
Systematic analysis of RNA-binding proteins identifies targetable therapeutic vulnerabilities in osteosarcoma
Nat Commun, 15 (1), 2810
DOI 10.1038/s41467-024-47031-y, PubMed 38561347