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Publications (original articles or review articles) published in 2022 from OUS - Department of Research and Development, Div. Clin. Neuroscience

54 publications found

Ahring PK, Liao VWY, Gardella E, Johannesen KM, Krey I, Selmer KK, Stadheim BF, Davis H, Peinhardt C, Koko M, Coorg RK, Syrbe S, Bertsche A, Santiago-Sim T, Diemer T, Fenger CD, Platzer K, Eichler EE, Lerche H, Lemke JR, Chebib M, Møller RS (2022)
Gain-of-function variants in GABRD reveal a novel pathway for neurodevelopmental disorders and epilepsy
Brain, 145 (4), 1299-1309
DOI 10.1093/brain/awab391, PubMed 34633442

Andries A, Ørstavik K, Rueegg CS, Eng S, Edvardsen E, Allen SM, Torsvik IK, Raastad T, Ruud E, Nilsen KB (2022)
Polyneuropathy in Adolescent Childhood Cancer Survivors: The PACCS Study
Pediatr Neurol, 140, 9-17
DOI 10.1016/j.pediatrneurol.2022.11.012, PubMed 36586183

Bahrami S, Hindley G, Winsvold BS, O'Connell KS, Frei O, Shadrin A, Cheng W, Bettella F, Rødevand L, Odegaard KJ, Fan CC, Pirinen MJ, Hautakangas HM, HUNT All-In Headache, Dale AM, Djurovic S, Smeland OB, Andreassen OA (2022)
Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools
Brain, 145 (1), 142-153
DOI 10.1093/brain/awab267, PubMed 34273149

Banitalebi H, Aaen J, Storheim K, Negård A, Myklebust TÅ, Grotle M, Hellum C, Espeland A, Anvar M, Indrekvam K, Weber C, Brox JI, Brisby H, Hermansen E (2022)
A novel MRI index for paraspinal muscle fatty infiltration: reliability and relation to pain and disability in lumbar spinal stenosis: results from a multicentre study
Eur Radiol Exp, 6 (1), 38
DOI 10.1186/s41747-022-00284-y, PubMed 35854201

Bardan I, Fagerli KM, Sexton J, Kvien TK, Bakland G, Mielnik P, Hu Y, Lien G, Flatø B, Molberg Ø, Kristianslund EK, Aga AB (2022)
Treatment Response to Tumor Necrosis Factor Inhibitors and Methotrexate Monotherapy in Adults With Juvenile Idiopathic Arthritis: Data From NOR-DMARD
J Rheumatol, 50 (4), 538-547
DOI 10.3899/jrheum.220645, PubMed 36379571

Bortsov AV, Parisien M, Khoury S, Martinsen AE, Lie MU, Heuch I, Hveem K, Zwart JA, Winsvold BS, Diatchenko L (2022)
Brain-specific genes contribute to chronic but not to acute back pain
Pain Rep, 7 (5), e1018
DOI 10.1097/PR9.0000000000001018, PubMed 35975136

Brune S, Høgestøl EA, de Rodez Benavent SA, Berg-Hansen P, Beyer MK, Leikfoss IS, Bos SD, Sowa P, Brunborg C, Andorra M, Pulido Valdeolivas I, Asseyer S, Brandt A, Chien C, Scheel M, Blennow K, Zetterberg H, Kerlero de Rosbo N, Paul F, Uccelli A, Villoslada P, Berge T, Harbo HF (2022)
Serum neurofilament light chain concentration predicts disease worsening in multiple sclerosis
Mult Scler, 28 (12), 1859-1870
DOI 10.1177/13524585221097296, PubMed 35658739

Bråten LCH, Grøvle L, Wigemyr M, Wilhelmsen M, Gjefsen E, Espeland A, Haugen AJ, Skouen JS, Brox JI, Zwart JA, Storheim K, Ostelo RW, Grotle M (2022)
Minimal important change was on the lower spectrum of previous estimates and responsiveness was sufficient for core outcomes in chronic low back pain
J Clin Epidemiol, 151, 75-87
DOI 10.1016/j.jclinepi.2022.07.012, PubMed 35926821

Bønes I, Karlberg AC, Liljeholm M, Fraser AN, Madsen JE, Fjalestad T (2022)
Pegs not superior to screws for fixation of fractures of the proximal humerus
J Orthop Surg Res, 17 (1), 66
DOI 10.1186/s13018-022-02947-3, PubMed 35109905

Cappelletti C, Eriksson A, Brorson IS, Leikfoss IS, Kråbøl O, Høgestøl EA, Vitelli V, Mjaavatten O, Harbo HF, Berven F, Bos SD, Berge T (2022)
Quantitative proteomics reveals protein dysregulation during T cell activation in multiple sclerosis patients compared to healthy controls
Clin Proteomics, 19 (1), 23
DOI 10.1186/s12014-022-09361-1, PubMed 35790914

Dagestad MH, Toppe MK, Kristoffersen PM, Gjefsen E, Andersen E, Assmus J, Vetti N, Espeland A (2022)
Dixon T2 imaging of vertebral bone edema: reliability and comparison with short tau inversion recovery
Acta Radiol, 65 (3), 273-283
DOI 10.1177/02841851221146130, PubMed 36560906

Dagestad MH, Vetti N, Kristoffersen PM, Zwart JA, Storheim K, Bakland G, Brox JI, Grøvle L, Marchand GH, Andersen E, Assmus J, Espeland A (2022)
Apparent diffusion coefficient values in Modic changes - interobserver reproducibility and relation to Modic type
BMC Musculoskelet Disord, 23 (1), 695
DOI 10.1186/s12891-022-05610-4, PubMed 35869480

Danielsen E, Mjåset C, Ingebrigtsen T, Gulati S, Grotle M, Rudolfsen JH, Nygaard ØP, Solberg TK (2022)
A nationwide study of patients operated for cervical degenerative disorders in public and private hospitals
Sci Rep, 12 (1), 12856
DOI 10.1038/s41598-022-17194-z, PubMed 35896806

Dunker Ø, Grotle M, Bu Kvaløy M, Uglem M, Løseth S, Hjelland IE, Kleggetveit IP, Allen SM, Dehli Vigeland M, Munk Killingmo R, Sand T, Nilsen KB (2022)
Accuracy of neuropathic pain measurements in patients with symptoms of polyneuropathy: validation of painDETECT, Self-Completed Leeds Assessment of Neuropathic Symptoms and Signs, and Douleur Neuropathique 4
Pain, 164 (5), 991-1001
DOI 10.1097/j.pain.0000000000002793, PubMed 36240023

Gheorghiu A, Brunborg C, Johannesen TB, Helseth E, Zwart JA, Wiedmann MKH (2022)
The impact of body mass index and height on risk for primary tumours of the spinal cord, spinal meninges, spinal and peripheral nerves in 1.7 million norwegian women and men: a prospective cohort study
Acta Oncol, 61 (1), 1-6
DOI 10.1080/0284186X.2021.2009562, PubMed 35001805

Hautakangas H, Winsvold BS, Ruotsalainen SE, Bjornsdottir G, Harder AVE, Kogelman LJA, Thomas LF, Noordam R, Benner C, Gormley P, Artto V, Banasik K, Bjornsdottir A, Boomsma DI, Brumpton BM, Burgdorf KS, Buring JE, Chalmer MA, de Boer I, Dichgans M, Erikstrup C, Färkkilä M, Garbrielsen ME, Ghanbari M, Hagen K et al. (2022)
Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles
Nat Genet, 54 (2), 152-160
DOI 10.1038/s41588-021-00990-0, PubMed 35115687

Hermansen E, Austevoll IM, Hellum C, Storheim K, Myklebust TÅ, Aaen J, Banitalebi H, Anvar M, Rekeland F, Brox JI, Franssen E, Weber C, Solberg TK, Furunes H, Grundnes O, Brisby H, Indrekvam K (2022)
Comparison of 3 Different Minimally Invasive Surgical Techniques for Lumbar Spinal Stenosis: A Randomized Clinical Trial
JAMA Netw Open, 5 (3), e224291
DOI 10.1001/jamanetworkopen.2022.4291, PubMed 35344046

Heuch I, Heuch I, Hagen K, Storheim K, Zwart JA (2022)
Does the risk of chronic low back pain depend on age at menarche or menopause? A population-based cross-sectional and cohort study: the Trøndelag Health Study
BMJ Open, 12 (2), e055118
DOI 10.1136/bmjopen-2021-055118, PubMed 35210341

Ho KKN, Skarpsno ES, Nilsen KB, Ferreira PH, Pinheiro MB, Hopstock LA, Johnsen MB, Steingrímsdóttir ÓA, Nielsen CS, Stubhaug A, Simic M (2022)
A bidirectional study of the association between insomnia, high-sensitivity C-reactive protein, and comorbid low back pain and lower limb pain
Scand J Pain, 23 (1), 110-125
DOI 10.1515/sjpain-2021-0197, PubMed 35420264

Ingebrigtsen T, Guldhaugen KA, Kristiansen JA, Kloster R, Grotle M, Solberg TK (2022)
Cervical spine surgery in the Northern Norway Regional Health Authority area in 2014-18
Tidsskr Nor Laegeforen, 142 (4)
DOI 10.4045/tidsskr.21.0628, PubMed 35239272

Jahre H, Grotle M, Smedbråten K, Richardsen KR, Côté P, Steingrímsdóttir ÓA, Nielsen C, Storheim K, Småstuen M, Stensland SØ, Øiestad BE (2022)
Low social acceptance among peers increases the risk of persistent musculoskeletal pain in adolescents. Prospective data from the Fit Futures Study
BMC Musculoskelet Disord, 23 (1), 44
DOI 10.1186/s12891-022-04995-6, PubMed 35027018

Khoury S, Parisien M, Thompson SJ, Vachon-Presseau E, Roy M, Martinsen AE, Winsvold BS, HUNT All-In Pain, Mundal IP, Zwart JA, Kania A, Mogil JS, Diatchenko L (2022)
Genome-wide analysis identifies impaired axonogenesis in chronic overlapping pain conditions
Brain, 145 (3), 1111-1123
DOI 10.1093/brain/awab359, PubMed 34788396

Killingmo RM, Chiarotto A, van der Windt DA, Storheim K, Bierma-Zeinstra SMA, Småstuen MC, Zolic-Karlsson Z, Vigdal ØN, Koes BW, Grotle M (2022)
Modifiable prognostic factors of high costs related to healthcare utilization among older people seeking primary care due to back pain: an identification and replication study
BMC Health Serv Res, 22 (1), 793
DOI 10.1186/s12913-022-08180-2, PubMed 35717179

Killingmo RM, Storheim K, van der Windt D, Zolic-Karlsson Z, Vigdal ØN, Kretz L, Småstuen MC, Grotle M (2022)
Healthcare utilization and related costs among older people seeking primary care due to back pain: findings from the BACE-N cohort study
BMJ Open, 12 (6), e057778
DOI 10.1136/bmjopen-2021-057778, PubMed 35725262

Kjønø LG, Killingmo RM, Vigdal ØN, Grotle M, Storheim K (2022)
Assessing physical workload among people with musculoskeletal disorders: validity and reliability of the physical workload questionnaire
BMC Musculoskelet Disord, 23 (1), 282
DOI 10.1186/s12891-022-05222-y, PubMed 35331205

Kristoffersen PM, Vetti N, Grøvle L, Brox JI, Haugli Bråten LC, Grotle M, Julsrud Haugen A, Rolfsen MP, Froholdt A, Skouen JS, Lutro O, Marchand GH, Anke A, Zwart JA, Storheim K, Assmus J, Espeland A (2022)
Amoxicillin Did Not Reduce Modic Change Edema in Patients With Chronic Low Back Pain: Subgroup Analyses of a Randomised Trial (the AIM Study)
Spine (Phila Pa 1976), 48 (3), 147-154
DOI 10.1097/BRS.0000000000004513, PubMed 36223435

Lie MU, Pedersen LM, Heuch I, Winsvold B, Gjerstad J, Hasvik E, Nygaard ØP, Grotle M, Matre D, Zwart JA, Nilsen KB (2022)
Low Back Pain With Persistent Radiculopathy; the Clinical Role of Genetic Variants in the Genes SOX5, CCDC26/GSDMC and DCC
Front Genet, 12, 757632
DOI 10.3389/fgene.2021.757632, PubMed 35140737

Major DH, Røe Y, Småstuen MC, van der Windt D, Sandbakk TB, Jæger M, Grotle M (2022)
Fear of movement and emotional distress as prognostic factors for disability in patients with shoulder pain: a prospective cohort study
BMC Musculoskelet Disord, 23 (1), 183
DOI 10.1186/s12891-022-05139-6, PubMed 35219313

Mishra A, Malik R, Hachiya T, Jürgenson T, Namba S, Posner DC, Kamanu FK, Koido M, Le Grand Q, Shi M, He Y, Georgakis MK, Caro I, Krebs K, Liaw YC, Vaura FC, Lin K, Winsvold BS, Srinivasasainagendra V, Parodi L, Bae HJ, Chauhan G, Chong MR, Tomppo L, Akinyemi R et al. (2022)
Stroke genetics informs drug discovery and risk prediction across ancestries
Nature, 611 (7934), 115-123
DOI 10.1038/s41586-022-05165-3, PubMed 36180795

Mjåset C, Solberg TK, Zwart JA, Småstuen MC, Kolstad F, Grotle M (2022)
Anterior surgical treatment for cervical degenerative radiculopathy: a prediction model for non-success
Acta Neurochir (Wien), 165 (1), 145-157
DOI 10.1007/s00701-022-05440-2, PubMed 36481873

Mjåset C, Zwart JA, Kolstad F, Solberg T, Grotle M (2022)
Clinical improvement after surgery for degenerative cervical myelopathy; A comparison of Patient-Reported Outcome Measures during 12-month follow-up
PLoS One, 17 (3), e0264954
DOI 10.1371/journal.pone.0264954, PubMed 35259164

Molteberg E, Taubøll E, Kverneland M, Iversen PO, Selmer KK, Nakken KO, Hofoss D, Thorsby PM (2022)
Substantial early changes in bone and calcium metabolism among adult pharmacoresistant epilepsy patients on a modified Atkins diet
Epilepsia, 63 (4), 880-891
DOI 10.1111/epi.17169, PubMed 35092022

Mørk M, Hoksrud AF, Soberg HL, Zucknick M, Heide M, Groven KS, Røe C (2022)
"Psychometric properties of the Norwegian foot function index revised short form"
BMC Musculoskelet Disord, 23 (1), 416
DOI 10.1186/s12891-022-05374-x, PubMed 35505330

Nustad HE, Steinsland I, Ollikainen M, Cazaly E, Kaprio J, Benjamini Y, Gervin K, Lyle R (2022)
Modeling dependency structures in 450k DNA methylation data
Bioinformatics, 38 (4), 885-891
DOI 10.1093/bioinformatics/btab774, PubMed 34788815

Olstad EW, Nordeng HME, Sandve GK, Lyle R, Gervin K (2022)
Low reliability of DNA methylation across Illumina Infinium platforms in cord blood: implications for replication studies and meta-analyses of prenatal exposures
Clin Epigenetics, 14 (1), 80
DOI 10.1186/s13148-022-01299-3, PubMed 35765087

Pedersen S, Kverneland M, Nakken KO, Rudi K, Iversen PO, Gervin K, Selmer KK (2022)
Genome-wide decrease in DNA methylation in adults with epilepsy treated with modified ketogenic diet: A prospective study
Epilepsia, 63 (9), 2413-2426
DOI 10.1111/epi.17351, PubMed 35762681

Porcheret K, Stensland SØ, Wentzel-Larsen T, Dyb G (2022)
Insomnia in survivors 8.5 years after the Utøya Island terrorist attack: transition from late adolescence to early adulthood - the Utøya study
Eur J Psychotraumatol, 13 (1), 2020472
DOI 10.1080/20008198.2021.2020472, PubMed 35096287

Rajan DS, Kour S, Fortuna TR, Cousin MA, Barnett SS, Niu Z, Babovic-Vuksanovic D, Klee EW, Kirmse B, Innes M, Rydning SL, Selmer KK, Vigeland MD, Erichsen AK, Nemeth AH, Millan F, DeVile C, Fawcett K, Legendre A, Sims D, Schnekenberg RP, Burglen L, Mercier S, Bakhtiari S, Francisco-Velilla R et al. (2022)
Autosomal Recessive Cerebellar Atrophy and Spastic Ataxia in Patients With Pathogenic Biallelic Variants in GEMIN5
Front Cell Dev Biol, 10, 783762
DOI 10.3389/fcell.2022.783762, PubMed 35295849

Rise HH, Brune S, Chien C, Berge T, Bos SD, Andorrà M, Valdeolivas IP, Beyer MK, Sowa P, Scheel M, Brandt AU, Asseyer S, Blennow K, Pedersen ML, Zetterberg H, de Schotten MT, Cellerino M, Uccelli A, Paul F, Villoslada P, Harbo HF, Westlye LT, Høgestøl EA (2022)
Brain disconnectome mapping derived from white matter lesions and serum neurofilament light levels in multiple sclerosis: A longitudinal multicenter study
Neuroimage Clin, 35, 103099
DOI 10.1016/j.nicl.2022.103099, PubMed 35772194

Rysstad T, Grotle M, Aasdahl L, Dunn KM, Tveter AT (2022)
Identification and Characterisation of Trajectories of Sickness Absence Due to Musculoskeletal Pain: A 1-Year Population-based Study
J Occup Rehabil, 33 (2), 277-287
DOI 10.1007/s10926-022-10070-7, PubMed 36103063

Rysstad T, Grotle M, Aasdahl L, Hill JC, Dunn KM, Tingulstad A, Tveter AT (2022)
Stratifying workers on sick leave due to musculoskeletal pain: translation, cross-cultural adaptation and construct validity of the Norwegian Keele STarT MSK tool
Scand J Pain, 22 (2), 325-335
DOI 10.1515/sjpain-2021-0144, PubMed 35148473

Samara A, Spildrejorde M, Sharma A, Falck M, Leithaug M, Modafferi S, Bjørnstad PM, Acharya G, Gervin K, Lyle R, Eskeland R (2022)
A multi-omics approach to visualize early neuronal differentiation from hESCs in 4D
iScience, 25 (11), 105279
DOI 10.1016/j.isci.2022.105279, PubMed 36304110

Saunders GRB, Wang X, Chen F, Jang SK, Liu M, Wang C, Gao S, Jiang Y, Khunsriraksakul C, Otto JM, Addison C, Akiyama M, Albert CM, Aliev F, Alonso A, Arnett DK, Ashley-Koch AE, Ashrani AA, Barnes KC, Barr RG, Bartz TM, Becker DM, Bielak LF, Benjamin EJ, Bis JC et al. (2022)
Genetic diversity fuels gene discovery for tobacco and alcohol use
Nature, 612 (7941), 720-724
DOI 10.1038/s41586-022-05477-4, PubMed 36477530

Shakeshaft A, Panjwani N, Collingwood A, Crudgington H, Hall A, Andrade DM, Beier CP, Fong CY, Gardella E, Gesche J, Greenberg DA, Hamandi K, Koht J, Lim KS, Møller RS, Ng CC, Orsini A, Rees MI, Rubboli G, Selmer KK, Striano P, Syvertsen M, Thomas RH, Zarubova J, Richardson MP et al. (2022)
Sex-specific disease modifiers in juvenile myoclonic epilepsy
Sci Rep, 12 (1), 2785
DOI 10.1038/s41598-022-06324-2, PubMed 35190554

Smedbråten K, Grotle M, Jahre H, Richardsen KR, Côté P, Steingrímsdóttir ÓA, Storheim K, Nielsen CS, Øiestad BE (2022)
Accumulation of health complaints is associated with persistent musculoskeletal pain two years later in adolescents: The Fit Futures study
PLoS One, 17 (12), e0278906
DOI 10.1371/journal.pone.0278906, PubMed 36580469

Smedbråten K, Grotle M, Jahre H, Richardsen KR, Småstuen MC, Skillgate E, Øiestad BE (2022)
Lifestyle behaviour in adolescence and musculoskeletal pain 11 years later: The Trøndelag Health Study
Eur J Pain, 26 (9), 1910-1922
DOI 10.1002/ejp.2012, PubMed 35851511

Stangeland H, Handal M, Skurtveit SO, Aakvaag HF, Dyb G, Wentzel-Larsen T, Baumann-Larsen M, Zwart JA, Storheim K, Stensland SØ (2022)
Killing pain?: a population-based registry study of the use of prescription analgesics, anxiolytics, and hypnotics among all children, adolescents and young adults in Norway from 2004 to 2019
Eur Child Adolesc Psychiatry, 32 (11), 2259-2270
DOI 10.1007/s00787-022-02066-8, PubMed 36030342

Stenshorne I, Syvertsen M, Ramm-Pettersen A, Henning S, Weatherup E, Bjørnstad A, Brüggemann N, Spetalen T, Selmer KK, Koht J (2022)
Monogenic developmental and epileptic encephalopathies of infancy and childhood, a population cohort from Norway
Front Pediatr, 10, 965282
DOI 10.3389/fped.2022.965282, PubMed 35979408

Taso M, Sommernes JH, Bjorland S, Zwart JA, Engebretsen KB, Sundseth J, Pripp AH, Kolstad F, Brox JI (2022)
What is success of treatment? Expected outcome scores in cervical radiculopathy patients were much higher than the previously reported cut-off values for success
Eur Spine J, 31 (10), 2761-2768
DOI 10.1007/s00586-022-07234-7, PubMed 35551484

Vigdal ØN, Storheim K, Killingmo RM, Småstuen MC, Grotle M (2022)
The one-year clinical course of back-related disability and the prognostic value of comorbidity among older adults with back pain in primary care
Pain, 164 (4), e207-e216
DOI 10.1097/j.pain.0000000000002779, PubMed 36083174

Vigeland MD, Flåm ST, Vigeland MD, Espeland A, Kristoffersen PM, Vetti N, Wigemyr M, Bråten LCH, Gjefsen E, Schistad EI, Haugen AJ, Froholdt A, Skouen JS, Zwart JA, Storheim K, Pedersen LM, Lie BA, AIM Study Group (2022)
Correlation between gene expression and MRI STIR signals in patients with chronic low back pain and Modic changes indicates immune involvement
Sci Rep, 12 (1), 215
DOI 10.1038/s41598-021-04189-5, PubMed 34997115

Yengo L, Vedantam S, Marouli E, Sidorenko J, Bartell E, Sakaue S, Graff M, Eliasen AU, Jiang Y, Raghavan S, Miao J, Arias JD, Graham SE, Mukamel RE, Spracklen CN, Yin X, Chen SH, Ferreira T, Highland HH, Ji Y, Karaderi T, Lin K, Lüll K, Malden DE, Medina-Gomez C et al. (2022)
A saturated map of common genetic variants associated with human height
Nature, 610 (7933), 704-712
DOI 10.1038/s41586-022-05275-y, PubMed 36224396

Aaen J, Banitalebi H, Austevoll IM, Hellum C, Storheim K, Myklebust TÅ, Anvar M, Weber C, Solberg T, Grundnes O, Brisby H, Indrekvam K, Hermansen E (2022)
The association between preoperative MRI findings and clinical improvement in patients included in the NORDSTEN spinal stenosis trial
Eur Spine J, 31 (10), 2777-2785
DOI 10.1007/s00586-022-07317-5, PubMed 35930062

Aanesen F, Grotle M, Rysstad TL, Tveter AT, Tingulstad A, Løchting I, Småstuen MC, van Tulder MW, Berg R, Foster NE, Wynne-Jones G, Sowden G, Fors E, Bagøien G, Hagen R, Storheim K, Øiestad BE (2022)
Effectiveness of adding motivational interviewing or a stratified vocational advice intervention to usual case management on return to work for people with musculoskeletal disorders: the MI-NAV randomised controlled trial
Occup Environ Med, 80 (1), 42-50
DOI 10.1136/oemed-2022-108637, PubMed 36428098